LOC102551027

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression LOC102551027 0.17 0.09 1.9e-03 0.13 0.05 0 0.11 5.3e-04 2.4e-02 2.5e-01 1.3e-03
2 Liver intron excision ratio chr2_30728561_30732053 0.08 0.03 2.6e-11 0.05 0.07 0.07 0.05 1.4e-06 3.3e-08 1.5e-08 2.3e-06
3 Liver intron excision ratio chr2_30728561_30805282 0.04 0.03 1.2e-03 0.01 0.02 0.03 0.03 8.9e-03 1.6e-03 8.6e-04 5.7e-04
4 IC gene expression LOC102551027 0.15 0.1 7.4e-04 0.07 0.08 0.07 0.07 4.7e-04 2.2e-04 8.8e-04 9.0e-04
5 Liver isoform ratio XR_351292.4 0.05 0.03 1.8e-04 0.01 0.03 0.02 0.02 3.1e-02 2.6e-04 2.5e-03 2.5e-03
6 Liver isoform ratio XR_010063712.1 0.05 0.03 8.3e-04 0.01 0.03 0.02 0.02 4.1e-02 3.2e-04 4.8e-03 3.3e-03
7 Liver intron excision ratio chr2_30728561_30731932 0.08 0.04 8.4e-05 0.02 0.03 0.03 0.03 2.6e-03 3.4e-04 2.7e-04 8.3e-04
8 PL gene expression LOC102551027 0.07 0.03 1.2e-04 0.01 0.03 0.04 0.03 7.1e-03 2.9e-04 6.5e-05 1.1e-04
9 Liver gene expression LOC102551027 0.19 0.06 0.0e+00 0.13 0.17 0.17 0.16 6.7e-14 4.2e-18 1.2e-18 1.4e-17
10 Liver intron excision ratio chr2_30728561_30731503 0.09 0.04 6.0e-07 0.05 0.06 0.05 0.06 6.1e-06 8.8e-07 6.1e-06 3.2e-07
11 Liver mRNA stability LOC102551027 0.07 0.04 1.2e-04 0.01 0.04 0.04 0.02 1.6e-02 5.7e-05 6.7e-05 2.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.10.30.5-0.30.30.10.5-0.6-0.30.30.4-0.50.0
Area under the delay curve0.30.41.3-1.11.0-0.50.8-0.30.30.4-0.00.70.40.8
BMI with tail1.03.66.2-2.52.3-2.22.3-2.12.12.1-1.20.61.70.1
BMI without tail0.52.96.6-2.32.0-1.51.7-1.61.72.6-1.60.71.3-0.7
Body weight0.93.815.9-4.02.9-1.42.3-1.21.22.0-0.31.80.30.6
Weight adjusted by age0.92.66.20.4-0.0-1.1-0.2-2.22.31.3-1.5-2.42.5-1.3
Bone surface0.10.10.6-0.50.4-0.00.50.1-0.1-0.00.20.50.10.7
Bone volume0.10.20.80.9-0.40.5-0.30.4-0.4-0.50.3-0.1-0.50.5
Breakpoint value in progressive ratio session0.20.30.80.6-0.1-0.10.40.6-0.6-0.50.70.9-0.60.0
Number of licking bursts0.30.94.9-0.2-0.71.1-0.30.8-0.70.9-0.80.2-0.3-2.2
Context. condit. distance diff. score0.81.02.61.1-1.30.7-1.5-0.00.1-0.0-0.6-1.5-0.0-1.6
Locomotion velocity, session 10.80.92.30.7-0.91.5-1.10.9-0.80.3-0.40.1-1.1-1.3
Locomotion distance, session 10.91.12.90.9-1.11.7-1.31.3-1.2-0.3-0.20.1-1.0-1.2
Locomotion velocity, session 20.40.52.10.0-0.31.4-0.80.8-0.60.4-0.70.1-0.9-0.3
Locomotion distance, session 21.62.25.21.7-1.92.3-1.81.7-1.6-0.2-0.4-0.4-1.1-1.5
Locomotion velocity, session 31.11.33.50.2-0.81.4-1.70.10.10.9-1.6-1.30.7-1.9
Locomotion distance, session 30.60.72.50.1-0.71.1-1.60.10.10.3-0.9-1.20.5-0.9
Stereotopy head waving bouts, day 31.21.52.50.6-1.21.6-1.21.6-1.5-1.01.10.4-1.5-0.7
Stereotopy head waving duration, day 30.70.92.3-0.50.20.10.50.9-1.0-1.01.51.5-1.20.7
Locomotion velocity, session 71.41.55.30.7-0.8-0.3-1.2-1.21.40.9-1.3-2.31.0-1.4
Locomotion distance, session 70.20.31.20.0-0.00.3-0.3-0.30.40.9-1.1-0.50.4-0.5
Stereotopy head waving bouts, day 71.21.46.00.4-1.61.5-1.50.5-0.30.4-0.4-1.30.1-2.4
Stereotopy head waving duration, day 70.30.42.2-0.0-0.60.3-0.7-0.20.30.3-0.0-0.90.1-1.5
Locomotion velocity, session 82.22.76.72.4-2.21.9-2.60.7-0.5-0.3-0.4-2.1-1.2-1.4
Locomotion distance, session 81.42.05.21.4-1.51.5-2.00.10.10.8-1.7-1.80.3-2.3
Degree of sensitization distance0.10.20.50.5-0.0-0.30.70.1-0.20.10.20.5-0.70.3
Degree of sensitization stereotypy1.11.35.30.3-1.10.7-1.1-0.30.40.8-1.0-1.70.9-2.3
Conditioned locomotion0.10.10.4-0.10.2-0.30.5-0.1-0.1-0.50.60.20.20.7
Cocaine response after cond. corrected0.20.41.1-0.20.6-0.20.3-0.60.60.9-1.1-0.10.80.0
Cocaine response after cond. not corrected0.40.51.5-0.30.6-0.40.3-0.80.91.2-1.2-0.30.8-0.3
Cocaine response before conditioning0.20.31.10.2-0.4-0.1-0.5-0.50.60.4-0.4-1.00.3-0.9
Saline control response0.71.02.1-0.31.0-1.41.2-1.51.40.6-0.4-0.50.90.7
Bone: connectivity density0.20.31.4-0.80.30.00.70.5-0.6-0.20.31.2-0.10.2
Bone: cortical apparent density1.01.63.71.7-1.70.9-1.90.00.1-0.3-0.4-1.90.5-1.6
Bone: cortical area1.62.68.72.0-0.2-1.6-0.3-1.10.9-2.02.1-1.60.42.9
Bone: cortical porosity0.10.10.40.5-0.20.4-0.10.3-0.30.10.30.2-0.5-0.7
Bone: cortical porosity0.30.31.21.1-0.70.3-0.40.3-0.4-0.30.6-0.3-0.5-0.5
Bone: cortical thickness1.42.47.22.7-1.1-1.2-0.9-1.11.0-1.81.5-2.30.61.6
Bone: cortical thickness1.31.63.90.20.9-1.60.3-2.02.00.5-0.2-1.51.11.4
Bone: cortical tissue density1.01.53.81.6-1.71.1-1.90.1-0.0-0.2-0.5-1.80.4-1.7
Condit. Reinf. active minus inactive responses1.31.54.60.1-0.0-0.20.2-1.01.11.7-2.1-1.11.7-1.6
Condit. Reinf. active-inactive response ratio1.51.64.30.10.2-1.10.5-1.61.61.2-1.7-1.22.1-1.0
Condit. Reinf. active responses1.21.65.6-0.00.10.30.1-0.80.92.1-2.4-0.91.3-1.8
Condit. Reinf. inactive responses0.20.21.0-0.20.30.6-0.10.00.11.0-0.9-0.0-0.2-0.3
Incentive salience index mean1.01.34.5-0.70.50.30.5-0.60.72.0-2.1-0.21.2-1.6
Condit. Reinf. lever presses0.40.61.8-0.70.11.1-0.10.5-0.41.1-1.00.5-0.2-1.3
Condit. Reinf. active minus inactive responses1.01.63.71.5-0.4-0.8-0.4-1.31.30.8-1.9-1.81.6-0.4
Condit. Reinf. active-inactive response ratio0.20.41.00.9-0.2-0.5-0.1-0.60.70.5-1.0-0.70.5-0.2
Condit. Reinf. active responses1.21.74.11.6-0.7-0.6-0.8-1.21.30.9-1.9-2.01.6-0.9
Condit. Reinf. inactive responses0.50.71.7-0.30.5-0.70.3-1.01.01.0-1.2-0.61.3-0.3
Condit. Reinf. lever presses0.50.72.01.4-0.5-0.3-0.5-0.60.70.5-1.2-1.20.7-0.8
Condit. Reinf. lever reinforcers received1.11.63.41.5-0.6-0.6-0.7-1.21.30.9-1.8-1.91.5-0.9
Conditioned reinforcement - actives0.31.13.0-0.91.2-1.71.3-1.00.90.00.40.60.31.7
Conditioned reinforcement - inactives0.10.20.50.4-0.3-0.5-0.2-0.30.2-0.70.2-0.6-0.10.7
Conditioned locomotion0.40.52.90.3-0.0-0.7-0.4-0.40.3-1.00.8-0.5-0.31.7
Patch foraging indifference point 0 sec0.41.13.2-1.81.4-0.40.7-0.91.01.5-1.0-0.10.80.1
Patch foraging indifference point AUC0.30.73.6-0.80.7-0.10.90.8-0.9-0.40.21.9-0.51.0
Delay disc. indifference point, 0s delay0.60.61.80.7-0.60.0-0.5-0.60.60.3-1.3-1.11.0-1.0
Delay disc. indifference point, 16s delay0.40.52.5-0.50.8-0.70.5-0.20.2-0.51.10.50.01.6
Delay disc. indifference point, 2s delay0.20.20.6-0.40.1-0.3-0.0-0.60.70.8-0.5-0.50.6-0.0
Delay disc. indifference point, 24s delay0.91.45.5-2.31.6-0.31.5-0.30.31.4-1.21.20.70.1
Delay disc. indifference point, 4s delay0.30.31.0-0.4-0.01.0-0.10.7-0.60.3-0.60.8-0.1-0.6
Delay disc. indifference point, 8s delay0.61.02.6-1.61.5-0.81.4-0.60.61.0-0.20.80.50.7
Indifference point function ln k0.10.20.70.40.2-0.3-0.2-0.80.80.3-0.1-0.80.4-0.0
Indifference point function log k0.10.20.70.40.2-0.3-0.2-0.80.80.3-0.1-0.80.4-0.0
Patch foraging total patch changes 0 sec0.41.03.3-1.81.5-0.30.7-0.80.91.5-0.90.10.70.2
Patch foraging total patch changes 12 sec0.60.83.1-1.81.1-0.51.0-0.50.51.1-0.80.70.7-0.1
Patch foraging total patch changes 18 sec0.20.50.9-1.00.7-0.90.4-0.80.90.8-0.8-0.30.70.4
Patch foraging total patch changes 24 sec0.41.32.7-1.61.4-1.40.9-1.31.30.8-0.6-0.11.30.9
Patch foraging total patch changes 6 sec0.71.24.6-2.11.6-0.11.2-0.10.21.3-1.01.20.5-0.1
Patch foraging time to switch 0 sec0.10.61.9-0.0-0.3-0.7-0.1-1.11.10.5-0.2-1.40.5-0.8
Patch foraging water rate 0 sec0.10.40.9-0.80.60.8-0.10.7-0.6-0.00.30.9-0.50.3
Patch foraging water rate 12 sec0.31.35.41.5-1.00.3-1.5-0.91.00.3-0.0-2.30.5-1.2
Patch foraging water rate 18 sec0.30.71.7-0.20.2-0.90.0-1.31.30.7-0.4-1.01.1-0.6
Patch foraging water rate 24 sec0.40.51.6-0.81.3-0.40.7-0.80.80.9-0.30.20.50.9
Patch foraging water rate 6 sec0.91.32.41.2-0.81.1-1.50.9-0.9-1.41.4-0.5-1.41.1
Seeking ratio, delayed vs. immediate footshock0.40.61.4-0.30.21.20.60.9-0.91.0-0.81.1-0.1-0.7
Distance traveled before self-admin0.10.21.3-0.7-0.00.10.30.2-0.20.50.20.5-0.1-1.1
Distance traveled after self-admin0.61.03.2-1.41.2-0.01.1-0.40.51.8-1.20.70.8-0.9
Extensor digitorum longus weight0.00.20.4-0.30.10.3-0.20.4-0.4-0.50.70.2-0.60.5
Bone: elastic displacement1.82.33.91.8-1.71.0-1.41.6-1.7-1.92.00.2-1.8-0.1
Bone: elastic work1.62.16.21.4-1.10.8-0.71.5-1.6-1.92.50.6-1.80.8
Bone: endosteal estimation0.10.31.3-0.60.9-0.60.4-0.60.60.30.0-0.10.31.1
Bone: endosteal perimeter0.20.41.20.00.7-1.00.5-0.80.70.10.2-0.40.61.1
Epididymis fat weight0.73.47.5-2.72.0-1.61.7-2.02.12.6-1.60.21.5-0.4
Delta time in closed arm before/after self-admin0.70.61.60.8-1.00.4-0.40.9-1.0-1.01.30.4-0.50.2
Delta time in open arm before/after self-admin2.73.26.20.20.4-1.30.2-2.42.51.7-2.5-2.32.3-1.3
Diff in mean of infusions in LGA sessions0.81.54.30.8-0.40.0-0.11.2-1.4-1.92.11.2-1.21.1
Delay discount exponential model param0.40.51.71.3-1.00.5-0.90.2-0.2-0.50.1-0.8-0.3-0.7
Extinction: sum of active levers before priming0.50.83.50.0-0.1-0.10.3-0.70.71.1-1.3-0.60.8-1.9
Active lever presses in extinction session 60.60.62.0-0.90.60.40.30.7-0.7-0.31.21.4-0.40.6
Bone: final force0.50.81.91.2-0.3-1.1-0.1-0.80.7-0.91.0-1.10.21.4
Bone: final moment0.50.82.21.0-0.2-1.0-0.1-0.70.6-0.91.2-0.90.11.5
Food consumed during 24 hour testing period2.04.112.2-0.30.5-1.70.6-2.42.42.2-2.8-1.83.5-1.2
Glucose1.01.56.72.6-1.70.6-1.7-0.10.1-0.6-0.5-1.80.3-0.2
Heart weight1.32.04.0-1.81.4-1.71.8-1.61.62.0-0.90.41.0-0.5
Delay discount hyperbolic model param0.30.41.41.2-0.90.3-0.80.1-0.1-0.50.1-0.8-0.3-0.6
Intermittent access intake day 1-15 change0.10.30.90.9-0.9-0.0-0.80.0-0.1-0.50.1-0.8-0.50.2
Intermittent access intake escalation0.10.30.90.9-1.00.1-0.80.2-0.2-0.70.1-0.7-0.50.1
Intermittent access intake escalation 20.20.31.10.7-0.5-0.4-0.30.0-0.1-1.00.8-0.4-0.50.7
Intermitt. access day 1 inactive lever presses0.22.04.01.9-2.00.8-2.00.7-0.7-2.01.4-1.6-0.90.2
Intermitt. access day 15 inactive lever presses0.42.25.71.1-2.42.0-2.31.2-1.1-0.6-0.2-1.2-0.5-1.9
Intermitt. access escalation Index0.30.92.70.8-1.01.6-1.60.7-0.5-0.5-0.1-0.4-0.2-1.4
Intermittent access day 1 total infusions0.61.75.6-2.41.5-1.31.3-1.11.11.8-0.60.90.7-0.1
Intermittent access day 15 total infusions0.20.61.2-0.60.2-1.10.3-1.01.01.1-1.0-0.50.6-0.1
Intermittent access terminal intake (last 3 days)0.20.31.1-0.50.0-1.00.3-0.80.70.8-0.6-0.30.30.1
Intermittent access total infusions0.81.02.4-1.10.7-1.30.8-1.21.21.5-1.0-0.10.70.1
Intermittent access day 1 locomotion0.40.71.4-1.10.9-1.21.0-0.70.60.60.30.6-0.01.2
Intermittent access day 15 total locomotion0.52.07.5-1.21.2-2.71.5-1.81.70.6-0.10.00.61.7
Intermittent access total locomotion0.40.51.5-0.70.5-1.20.4-0.90.80.40.2-0.1-0.01.2
Intermittent access standard deviation0.00.20.8-0.2-0.4-0.2-0.3-0.30.30.7-0.6-0.60.4-0.9
Left kidney weight1.612.734.4-5.95.0-3.34.6-2.92.94.1-1.72.52.00.8
Right kidney weight1.913.629.8-5.55.1-3.94.7-3.33.34.0-2.02.22.51.6
Cocaine induced anxiety0.10.30.7-0.50.6-0.30.80.1-0.2-0.40.40.80.20.5
Post-drug Anxiety0.60.71.6-1.31.1-0.91.2-0.40.30.30.21.10.50.8
Baseline Anxiety0.10.21.2-0.5-0.10.3-0.2-0.00.11.1-0.4-0.1-0.2-0.2
Tail length0.21.25.1-2.31.80.00.9-0.30.51.5-0.41.1-0.30.1
Length with tail0.52.410.9-3.32.4-0.41.5-0.20.31.00.71.8-0.91.4
Length without tail0.31.45.6-2.41.8-0.41.4-0.50.50.70.71.0-0.41.4
Times rat made contact with spout3.43.98.1-1.01.3-2.01.8-2.22.22.6-2.4-0.42.9-1.4
Lifetime Intake0.50.72.3-1.30.7-0.80.7-0.80.81.5-0.70.30.40.0
Liver weight, left2.94.98.3-2.22.5-2.52.3-2.82.82.9-2.1-0.21.9-0.1
Liver weight, right1.11.96.2-2.52.1-0.71.5-1.01.11.8-1.00.70.70.4
Locomotor activity0.71.22.6-0.10.1-0.4-0.1-1.21.31.6-1.5-1.31.2-1.2
Locomotor testing distance2.04.910.4-0.91.5-2.61.0-3.23.22.4-2.1-1.93.0-0.3
Locomotor testing rearing1.24.69.3-0.61.5-2.81.5-3.13.02.0-1.8-1.72.90.3
Locomotion in novel chamber0.20.30.80.9-0.70.3-0.6-0.10.10.4-0.7-0.60.3-0.4
Locomotion in novel chamber post-restriction0.61.94.4-0.4-0.32.0-0.12.1-2.10.20.51.9-1.9-0.4
Fecal boli incidents, locomotor time 10.41.14.3-1.1-0.40.40.21.1-1.1-0.82.11.3-1.20.4
Change in fecal boli incidents, locomotor task0.20.20.60.4-0.40.8-0.40.3-0.30.3-0.1-0.3-0.6-0.7
Time >=10cm from walls, locomotor time 12.73.48.80.7-1.11.5-1.12.2-2.2-2.63.01.2-2.20.8
Bouts of movement, locomotor time 10.50.61.70.10.7-1.30.9-1.31.30.5-0.1-0.30.4-0.2
Total resting periods, locomotor time 10.40.51.4-0.10.8-1.21.0-1.11.00.40.0-0.00.30.1
Rest time, locomotor task time 10.40.72.20.7-1.10.9-0.90.3-0.21.1-0.7-0.8-0.6-1.5
Distance moved, locomotor task time 10.41.02.3-0.81.4-1.11.0-1.21.20.2-0.8-0.21.50.9
Vertical activity count, locomotor time 10.21.22.7-0.41.5-1.41.1-1.21.1-0.20.00.11.41.6
Time >=10cm from walls, locomotor time 20.10.20.8-0.5-0.00.9-0.30.6-0.6-0.10.40.5-0.2-0.1
Bouts of movement, locomotor time 20.10.20.5-0.3-0.30.7-0.50.6-0.6-0.3-0.40.60.2-0.4
Total resting periods, locomotor time 20.10.30.8-0.0-0.60.8-0.70.7-0.6-0.1-0.60.40.1-0.9
Rest time, locomotor task time 20.81.33.31.5-1.4-0.3-0.7-0.70.70.6-1.1-1.80.9-1.7
Distance moved, locomotor task time 21.11.42.7-1.11.6-1.00.9-1.41.41.0-1.5-0.31.50.7
Vertical activity count, locomotor time 20.41.01.8-0.31.2-0.70.6-1.31.31.3-1.1-0.41.30.6
Light reinforcement 10.31.43.5-1.01.9-1.31.6-1.00.90.9-0.60.81.01.2
Light reinforcement 20.30.72.8-1.20.40.20.60.9-1.0-0.41.01.7-0.40.3
Bone: marrow area0.10.31.3-0.70.8-0.50.4-0.50.60.30.0-0.10.21.1
Bone: maximum diameter0.91.77.70.01.1-1.91.0-1.21.1-0.71.1-0.30.82.8
Bone: maximum force0.51.02.10.90.0-1.40.0-1.31.2-0.50.6-1.20.71.5
Bone: maximum moment0.50.92.40.70.1-1.30.0-1.21.1-0.50.8-1.10.51.5
Mean time between licks in bursts0.10.61.7-0.30.5-1.01.0-0.1-0.0-0.81.00.8-0.51.3
Mean num. licks in bursts1.02.76.7-0.21.4-2.61.4-2.42.20.7-0.7-0.72.31.4
Cd content in liver0.91.02.31.00.1-1.10.2-1.51.40.4-0.4-1.51.20.1
Co content in liver1.21.43.50.20.8-1.00.3-1.81.91.4-0.8-1.31.4-0.5
Cu content in liver0.10.10.50.0-0.40.2-0.10.2-0.2-0.10.40.0-0.4-0.7
Fe content in liver0.70.81.91.4-1.10.8-0.70.8-0.8-1.11.0-0.4-1.20.1
K content in liver0.80.81.5-0.81.2-0.61.2-0.80.81.0-0.70.20.71.0
Mg content in liver0.30.31.01.0-0.80.0-0.4-0.20.1-0.50.4-1.00.00.5
Mn content in liver1.11.23.71.9-1.50.8-1.70.3-0.3-1.10.6-1.4-0.50.0
Na content in liver0.60.71.9-1.21.3-0.61.4-0.50.40.50.10.9-0.10.9
Rb content in liver0.30.41.00.40.2-1.00.4-1.00.90.30.3-0.80.60.3
Se content in liver0.70.82.31.2-1.11.1-1.50.2-0.1-0.1-0.4-1.4-0.1-0.8
Sr content in liver0.20.10.70.20.40.4-0.2-0.30.40.10.0-0.3-0.10.8
Zn content in liver0.00.00.1-0.20.1-0.00.2-0.30.30.20.20.0-0.0-0.2
Bone: minimum diameter1.22.47.12.7-1.5-0.3-1.6-0.30.3-1.91.4-2.3-0.01.6
Time in familiar zone, hab. session 10.20.20.7-0.1-0.40.4-0.30.5-0.50.10.20.3-0.4-0.8
Time in novel zone, hab. session 11.51.73.7-1.21.4-1.91.4-1.61.71.1-1.0-0.31.50.3
Total zone transitions, hab. session 10.81.23.90.5-1.12.0-1.41.3-1.20.1-0.4-0.1-0.9-1.3
Total locomotion distance, hab. session 11.01.42.80.7-1.11.5-1.41.6-1.5-1.00.90.3-1.7-0.7
Locomotion velocity, hab. session 11.52.13.91.2-1.31.9-1.41.9-1.9-1.51.30.4-2.0-0.1
Time in familiar zone, hab. session 21.01.12.1-0.81.4-1.41.1-1.31.20.5-0.40.31.11.2
Time in novel zone, hab. session 20.20.21.00.1-0.30.4-0.00.1-0.10.7-0.6-0.40.0-1.0
Total zone transitions, hab. session 20.60.82.0-0.5-0.21.4-0.60.8-0.71.1-1.20.4-0.4-1.3
Total locomotion distance, hab. session 20.20.30.70.5-0.70.8-0.80.6-0.50.0-0.5-0.2-0.3-0.7
Locomotion velocity, hab. session 20.30.41.10.5-0.71.0-0.80.8-0.70.1-0.7-0.1-0.4-0.8
Novel to familiar place preference ratio0.10.10.30.3-0.3-0.3-0.2-0.10.10.0-0.1-0.50.5-0.2
Novelty place preference0.20.20.70.1-0.1-0.5-0.1-0.50.50.3-0.3-0.80.9-0.2
Time in novel zone, NPP test0.10.20.60.2-0.1-0.5-0.0-0.40.40.1-0.2-0.70.8-0.1
Total zone transitions, NPP test1.42.05.90.4-1.32.4-1.41.9-1.8-0.0-0.60.6-1.2-1.9
Total locomotion distance, NPP test1.82.54.81.4-2.12.2-2.01.9-1.8-1.00.4-0.2-1.5-1.4
Locomotion velocity, NPP test1.72.45.01.3-2.12.2-2.01.9-1.8-0.90.3-0.2-1.4-1.4
Intraocular pressure1.52.56.01.9-2.12.4-2.41.5-1.4-0.5-0.8-1.20.1-1.2
Delta distance traveled before/after self-admin0.70.82.0-0.71.4-0.61.1-0.70.71.0-1.10.50.80.5
Delta ambulatory time before/after self-admin0.81.33.4-0.61.4-0.71.2-1.21.21.7-1.8-0.01.2-0.0
Parametrial fat weight0.10.20.40.10.5-0.60.4-0.60.60.7-0.1-0.2-0.1-0.5
Pavlov. Cond. lever latency0.30.41.30.6-0.3-0.9-0.2-0.70.7-0.1-0.3-1.10.80.0
Pavlov. Cond. magazine entry latency1.11.44.2-2.12.0-0.41.6-0.30.41.1-0.31.6-0.00.5
Pavlov. Cond. change in total contacts0.50.51.6-0.81.2-0.51.1-0.50.40.4-0.20.70.21.1
Pavlov. Cond. index score0.70.92.5-1.61.5-0.11.2-0.00.00.60.01.5-0.20.6
Pavlov. Cond. latency score0.60.72.5-1.41.3-0.11.10.2-0.20.30.31.6-0.40.6
Pavlov. Cond. lever contacts0.30.30.8-0.30.10.9-0.10.7-0.6-0.10.50.7-0.80.5
Pavlov. Cond. magazine entry number2.53.18.72.6-2.91.3-2.41.3-1.4-1.91.0-1.4-0.9-0.8
Pavlov. Cond. intertrial magazine entries0.30.30.80.8-0.90.9-0.80.6-0.6-0.3-0.2-0.4-0.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.50.72.2-1.51.30.20.90.1-0.10.6-0.11.4-0.30.5
Pavlov. Cond. response bias1.11.34.2-1.92.1-0.31.4-0.70.71.4-0.61.10.30.7
Pavlov. Cond. lever latency0.50.72.0-0.70.00.30.20.8-0.9-1.01.41.0-1.10.7
Pavlov. Cond. magazine entry latency2.43.46.6-1.01.9-2.31.7-2.62.51.9-1.6-0.62.20.7
Pavlov. Cond. change in total contacts0.20.51.31.0-0.1-0.6-0.2-0.90.90.3-0.6-1.10.70.4
Pavlov. Cond. index score1.22.04.10.01.0-1.50.7-2.02.01.5-1.6-1.21.90.2
Pavlov. Cond. latency score1.62.55.0-0.31.2-1.70.8-2.22.21.7-1.9-1.12.20.2
Pavlov. Cond. lever contacts0.60.92.20.9-0.2-0.4-0.2-0.91.01.0-1.5-1.31.2-0.9
Pavlov. Cond. magazine entry number2.33.06.00.6-1.72.4-1.62.4-2.4-1.31.30.7-2.2-1.2
Pavlov. Cond. intertrial magazine entries0.51.01.80.5-0.80.8-0.91.3-1.3-1.31.20.4-1.20.6
Pavlov. Cond. lever-magazine prob. diff.1.52.35.00.01.0-1.70.7-2.22.21.6-1.7-1.32.00.0
Pavlov. Cond. response bias0.70.91.80.70.3-1.00.4-1.31.30.9-1.1-1.11.3-0.1
Time in closed arm before self-admin0.50.91.71.2-1.01.3-1.31.1-1.0-0.90.3-0.0-1.10.2
Time in closed arm after self-admin1.31.52.31.1-1.51.2-1.31.5-1.5-1.21.40.3-1.40.2
Time in open arm before self-admin1.11.44.5-1.91.5-1.12.1-0.40.31.00.11.50.20.2
Time in open arm after self-admin3.63.98.6-1.41.6-1.31.7-2.22.32.8-2.9-0.92.2-1.4
Bone: periosteal estimation0.61.46.21.00.3-1.2-0.1-1.00.9-1.11.4-1.10.32.5
Bone: periosteal perimeter0.91.78.21.00.3-1.60.3-0.80.7-1.51.8-0.70.22.9
Bone: post-yield work0.20.31.7-0.50.7-0.30.7-0.10.1-0.20.30.5-0.21.3
Progressive ratio test 1 active lever presses0.10.20.9-0.90.3-0.40.2-0.30.30.9-0.20.3-0.10.1
Progressive ratio test 1 breakpoint0.10.20.8-0.90.3-0.30.1-0.30.30.9-0.10.2-0.10.2
Progressive ratio test 1 inactive lever presses0.10.31.0-1.0-0.00.7-0.40.5-0.50.30.20.6-0.60.1
Progressive ratio test 2 active lever presses1.31.94.3-1.21.3-2.11.6-1.61.51.6-1.20.30.90.8
Progressive ratio test 2 breakpoint1.31.73.7-1.11.2-1.91.4-1.51.51.6-1.30.20.90.6
Progressive ratio test 2 inactive lever presses0.30.91.9-1.20.9-1.40.8-1.11.10.9-0.60.00.50.9
Incentive Sensitization - Responses1.02.95.2-1.31.8-2.32.2-1.91.81.8-1.90.51.50.2
Incentive Sensitization - Breakpoint1.22.74.7-1.31.7-2.22.1-1.81.81.8-2.00.41.50.1
Sum of active levers in priming session hrs 5-60.20.20.60.50.10.20.40.4-0.5-0.1-0.10.8-0.4-0.3
Progressive ratio0.41.34.2-0.10.6-0.90.5-1.41.51.3-2.0-1.01.3-0.6
Food seeking constrained by brief footshock0.30.41.8-0.30.8-0.30.6-0.60.71.3-0.70.30.0-0.1
Seeking ratio, punishment vs. effort0.30.61.8-0.1-0.00.7-0.11.0-1.0-0.51.31.1-0.90.6
Retroperitoneal fat weight0.42.04.5-1.21.0-1.10.6-1.82.02.1-1.7-0.91.2-1.1
Reaction time number correct0.20.82.91.2-1.00.8-1.5-0.20.2-0.0-0.5-1.70.40.3
Reaction time mean minus median0.10.61.51.1-1.10.8-1.00.7-0.6-0.1-0.4-0.2-0.2-1.2
Reaction time mean minus median AUC0.00.20.70.5-0.70.3-0.50.2-0.20.1-0.4-0.20.2-0.8
Reaction time num false alarms0.30.41.4-0.50.8-0.80.9-0.50.4-0.20.00.40.51.2
Reaction time num false alarms AUC0.20.51.2-0.80.9-0.91.1-0.50.3-0.20.30.80.21.1
Reaction time trials correct on left0.20.82.91.2-1.00.8-1.5-0.20.2-0.0-0.5-1.70.40.3
Reaction time trials on left0.31.03.41.4-1.10.8-1.7-0.20.3-0.0-0.6-1.90.50.2
Reaction time mean0.81.75.12.3-1.90.2-1.6-0.30.3-0.3-1.0-1.90.7-1.5
Reaction time mean AUC0.51.23.82.0-1.70.3-1.4-0.10.1-0.3-0.8-1.50.4-1.3
Median of all reaction times0.91.44.02.0-1.5-0.3-1.2-0.60.6-0.4-0.8-1.90.8-1.0
Reaction time omissions1.62.56.22.5-2.10.0-1.6-0.40.50.2-1.6-2.21.6-1.9
Reaction time false alarm rate0.81.13.2-1.41.3-1.11.8-0.30.1-0.10.51.7-0.10.7
Reaction time premature initiation rate0.91.55.9-2.41.8-1.31.2-0.90.91.2-0.20.90.20.2
Reaction time premature initiations0.20.61.8-1.30.9-0.70.0-0.91.01.0-0.4-0.40.50.2
Std. dev. reaction times0.41.53.91.8-1.91.0-1.50.7-0.6-0.2-0.7-0.9-0.0-2.0
Reaction time trials completed0.31.03.41.4-1.10.8-1.7-0.20.3-0.0-0.6-1.90.50.2
Reaction time trials AUC0.31.03.91.4-1.00.5-1.5-0.40.50.0-0.6-2.00.70.3
Run reversals in cocaine runway, females0.80.92.20.7-0.80.7-0.71.2-1.2-0.81.20.6-1.50.3
Run reversals in cocaine runway, males1.21.33.00.3-0.91.4-0.41.7-1.7-1.11.11.2-1.3-0.4
Latency to leave start box in cocaine runway1.42.05.20.2-0.61.4-0.42.2-2.3-1.31.41.7-1.50.5
Latency to leave start box in cocaine runway, F0.81.12.0-0.20.30.60.11.2-1.3-1.11.41.4-1.21.3
Latency to leave start box in cocaine runway, M1.11.02.60.7-1.21.1-0.61.6-1.6-0.70.50.7-0.8-0.6
Std. dev. time between licks in bursts0.50.92.8-1.51.1-0.51.60.1-0.20.30.31.7-0.50.5
Total sessions with >9 infusions0.20.31.8-0.80.40.1-0.0-0.30.31.3-0.50.3-0.1-0.3
Short access day 1 total inactive lever presses0.10.20.5-0.60.3-0.20.5-0.10.10.7-0.50.5-0.10.3
Short access day 10 total inactive lever presses0.10.61.10.7-0.70.9-0.90.7-0.7-1.00.6-0.3-1.00.4
Short access day 1 total infusions0.20.40.8-0.90.00.8-0.20.6-0.60.50.30.8-0.7-0.5
Short access day 10 total infusions0.10.10.3-0.1-0.2-0.6-0.2-0.50.40.50.3-0.50.00.2
Short access total infusions0.20.31.3-1.00.30.30.10.1-0.11.1-0.10.6-0.4-0.4
Short access day 1 locomotion0.10.10.3-0.40.0-0.1-0.6-0.40.40.50.1-0.2-0.00.3
Short access day 10 total locomotion0.72.97.52.2-2.71.6-2.71.1-1.0-1.10.9-1.9-1.3-0.3
Short access total locomotion0.40.62.10.7-1.10.6-1.50.3-0.2-0.20.7-0.8-0.80.4
One hour access (0.3 mA shock)0.50.51.7-1.30.7-0.90.9-0.60.50.9-0.40.60.30.3
Compulsive drug intake0.60.92.8-0.9-0.01.20.61.3-1.30.3-0.31.7-0.6-1.1
One hour access (shock baseline)0.30.82.3-0.40.5-1.50.2-1.41.30.5-0.2-0.70.61.0
Social response proportion5.06.312.23.2-3.52.8-3.02.8-2.8-2.61.4-0.6-2.2-1.0
Social responses1.21.64.02.0-1.81.3-2.01.0-0.9-1.00.2-1.0-0.6-0.8
Social time0.50.83.31.8-1.01.3-1.30.5-0.4-0.3-0.2-0.8-0.4-0.4
Soleus weight0.51.63.1-1.60.60.60.11.2-1.2-1.11.61.6-1.31.8
Bone: stiffness0.61.12.80.00.7-1.40.5-1.71.60.5-0.6-1.01.30.9
Tibialis anterior weight2.17.313.52.4-3.73.6-3.23.3-3.2-2.11.2-0.5-2.6-1.8
Time to tail flick, vehicle, before self-admin0.20.31.3-0.40.5-0.20.00.1-0.1-1.10.90.1-0.00.7
Time to tail flick, vehicle, after self-admin0.51.02.2-0.91.0-1.41.5-0.40.3-1.00.61.20.71.0
Time to tail flick, test, before self-admin0.50.62.11.0-0.8-0.2-0.9-0.70.70.5-0.2-1.40.2-0.7
Time to tail flick, test, after self-admin0.60.62.01.4-1.21.0-0.80.4-0.4-0.3-0.4-0.8-0.2-0.9
Delta time to tail flick, vehicle, before/after SA0.20.20.7-0.10.2-0.80.9-0.40.3-0.0-0.20.40.50.3
Delta time to tail flick, test, before/after SA0.70.82.00.2-0.31.2-0.21.4-1.4-1.20.50.9-0.90.4
Tibia length0.41.24.70.20.9-1.61.3-1.10.9-0.40.9-0.20.42.2
Ambulatory time before self-admin0.10.21.2-0.60.10.10.30.3-0.20.50.30.6-0.1-1.1
Ambulatory time after self-admin0.50.72.2-0.51.0-0.20.8-0.60.71.5-1.20.20.9-0.9
Bone: tissue strength0.30.30.70.9-0.2-0.90.2-0.20.1-0.70.2-0.10.50.7
Total heroin consumption0.60.71.71.3-0.3-0.30.50.6-0.8-1.31.20.7-0.90.5
Bone: trabecular number0.00.10.3-0.30.30.10.50.1-0.10.3-0.20.5-0.1-0.0
Bone: trabecular spacing0.60.93.31.6-1.1-0.1-1.2-0.50.6-0.4-0.1-1.80.6-0.6
Bone: trabecular thickness1.72.34.41.5-1.61.6-1.21.8-1.9-1.71.50.1-2.10.4
Bone: trabecular tissue density0.61.04.00.6-1.01.1-1.00.4-0.20.9-1.5-0.60.2-2.0
Water consumed over 24 hours2.85.411.4-1.41.4-1.81.5-2.62.63.4-3.1-0.93.2-2.1
Number of responses in last shaping day0.30.31.3-0.90.30.3-0.2-0.30.41.1-0.8-0.40.5-0.5