Hub : Genes

LOC102550580

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XR_005490722.2 0.04 0.03 1.8e-07 0.03 0.04 0.04 0.04 1.3e-04 1.1e-05 1.4e-05 9.8e-06
2 Brain intron excision ratio chr10_81806378_81809559 0.03 0.03 3.6e-03 0.03 0.03 0.03 0.03 6.2e-04 1.6e-03 1.5e-03 8.4e-04
3 Adipose alternative polyA XR_010055449.1 0.04 0.02 1.5e-06 0.04 0.02 0.04 0.04 9.6e-06 9.6e-04 9.4e-06 7.4e-05
4 Adipose intron excision ratio chr10_81811109_81812728 0.03 0.02 4.6e-03 0.02 0.02 0.02 0.02 8.9e-04 5.0e-03 2.1e-03 1.3e-03
5 Adipose alternative polyA XR_005490722.2 0.04 0.03 3.2e-07 0.03 0.04 0.03 0.04 1.1e-04 2.8e-05 2.1e-04 3.6e-05
6 Adipose alternative polyA XR_005490722.2 0.03 0.02 1.3e-04 0.01 0.03 0.01 0.02 1.0e-02 7.5e-04 1.9e-02 4.0e-03
7 Liver alternative polyA XR_357850.5 0.02 0.02 8.3e-03 0.01 0.01 0.01 0.01 1.5e-02 1.0e-02 5.0e-02 1.3e-02
8 Adipose gene expression LOC102550580 0.09 0.06 7.4e-13 0.08 0.03 0.08 0.04 2.6e-09 6.6e-04 1.3e-09 4.2e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density1.42.42.81.71.6-1.6-1.41.71.7-1.6-0.9
Area under the delay curve0.40.52.1-0.3-0.70.30.4-0.5-0.50.41.4
BMI with tail18.664.281.88.49.0-8.5-8.08.38.3-8.1-4.6
BMI without tail1.44.35.42.32.3-2.3-2.22.12.1-2.1-0.6
Body weight1.14.75.62.02.3-2.1-1.92.42.4-2.3-1.8
Weight adjusted by age0.50.73.5-0.4-1.00.30.3-0.6-0.60.61.9
Bone surface0.50.91.31.01.1-1.0-0.91.01.0-0.9-0.5
Bone volume1.32.32.71.51.6-1.6-1.31.61.6-1.5-1.2
Breakpoint value in progressive ratio session2.53.03.7-1.9-1.71.71.1-1.8-1.81.81.9
Number of licking bursts0.60.91.6-1.1-0.81.01.3-0.7-0.70.8-1.1
Context. condit. distance diff. score0.70.81.21.11.0-1.1-0.90.90.9-0.90.2
Locomotion velocity, session 10.30.32.1-0.10.20.10.10.20.2-0.2-1.4
Locomotion distance, session 14.05.06.7-2.6-2.42.52.5-2.3-2.32.3-0.0
Locomotion velocity, session 21.31.52.0-1.2-1.41.21.1-1.2-1.21.11.4
Locomotion distance, session 25.37.49.7-3.1-3.13.03.0-2.7-2.72.80.1
Locomotion velocity, session 30.20.30.60.50.3-0.4-0.80.30.3-0.40.7
Locomotion distance, session 31.71.92.4-1.2-1.61.30.9-1.5-1.51.41.5
Stereotopy head waving bouts, day 34.45.26.12.12.4-2.1-2.22.32.4-2.3-2.5
Stereotopy head waving duration, day 33.44.14.51.92.1-2.0-1.82.12.1-2.1-2.0
Locomotion velocity, session 71.51.61.9-1.2-1.11.31.3-1.3-1.31.4-1.2
Locomotion distance, session 76.27.89.9-3.0-2.92.93.1-2.9-2.93.0-0.9
Stereotopy head waving bouts, day 70.20.30.40.40.5-0.5-0.70.60.6-0.6-0.0
Stereotopy head waving duration, day 70.30.40.80.40.5-0.5-0.90.60.6-0.70.6
Locomotion velocity, session 80.50.61.00.80.7-0.8-1.00.60.6-0.70.7
Locomotion distance, session 80.71.01.4-1.0-1.20.91.0-1.0-1.01.01.0
Degree of sensitization distance0.50.52.6-0.5-0.20.50.8-0.4-0.40.5-1.6
Degree of sensitization stereotypy0.20.20.3-0.5-0.40.50.3-0.3-0.30.30.6
Conditioned locomotion1.61.82.91.71.4-1.5-1.21.41.3-1.4-0.2
Cocaine response after cond. corrected5.36.37.72.62.8-2.7-2.52.72.7-2.7-1.0
Cocaine response after cond. not corrected2.93.44.31.92.1-2.1-2.01.91.9-1.9-0.2
Cocaine response before conditioning2.83.33.8-1.9-1.91.91.6-1.9-1.91.91.4
Saline control response0.10.10.3-0.10.20.20.5-0.5-0.50.50.3
Bone: connectivity density0.20.40.60.80.5-0.7-0.80.60.6-0.60.4
Bone: cortical apparent density5.27.28.6-2.8-2.72.72.5-2.9-2.92.91.7
Bone: cortical area0.30.51.00.91.0-0.9-0.70.60.6-0.60.2
Bone: cortical porosity0.30.30.30.50.6-0.6-0.40.50.5-0.6-0.5
Bone: cortical porosity0.40.50.60.60.7-0.7-0.60.70.7-0.7-0.8
Bone: cortical thickness0.10.10.20.40.4-0.3-0.2-0.2-0.20.20.4
Bone: cortical thickness0.91.12.9-0.7-1.20.70.6-1.0-1.00.91.7
Bone: cortical tissue density5.87.99.5-3.0-2.82.92.7-3.1-3.13.11.7
Condit. Reinf. active minus inactive responses1.11.22.1-1.2-0.71.21.4-0.9-0.91.0-1.4
Condit. Reinf. active-inactive response ratio0.20.21.40.20.5-0.1-0.00.20.2-0.2-1.2
Condit. Reinf. active responses1.01.21.9-1.4-1.11.31.3-0.9-0.91.0-0.9
Condit. Reinf. inactive responses0.81.01.8-1.2-1.31.21.0-0.9-0.90.90.6
Incentive salience index mean1.51.82.7-1.6-1.31.61.6-1.3-1.21.3-0.7
Condit. Reinf. lever presses1.72.53.4-1.8-1.71.81.7-1.5-1.51.50.2
Condit. Reinf. active minus inactive responses0.10.10.3-0.3-0.20.20.4-0.1-0.10.1-0.6
Condit. Reinf. active-inactive response ratio0.20.31.8-0.2-0.10.10.40.10.1-0.1-1.3
Condit. Reinf. active responses0.00.00.1-0.3-0.20.10.3-0.2-0.20.2-0.0
Condit. Reinf. inactive responses0.10.21.0-0.1-0.10.00.1-0.4-0.40.41.0
Condit. Reinf. lever presses0.60.94.1-0.6-0.80.50.4-0.8-0.80.62.0
Condit. Reinf. lever reinforcers received0.10.10.2-0.4-0.30.30.4-0.4-0.40.40.3
Conditioned reinforcement - actives0.50.83.3-1.0-0.60.90.9-0.2-0.20.2-1.8
Conditioned reinforcement - inactives0.10.21.0-0.10.20.00.2-0.2-0.20.3-1.0
Conditioned locomotion1.01.23.10.60.6-0.6-0.71.31.3-1.4-1.8
Patch foraging indifference point 0 sec1.12.02.71.41.1-1.5-1.41.31.3-1.51.6
Patch foraging indifference point AUC0.10.10.2-0.0-0.20.20.2-0.3-0.30.3-0.4
Delay disc. indifference point, 0s delay0.70.84.7-0.1-0.50.3-0.0-0.7-0.70.72.2
Delay disc. indifference point, 16s delay0.70.71.01.00.6-0.9-0.90.90.8-1.00.7
Delay disc. indifference point, 2s delay0.20.20.4-0.2-0.60.20.3-0.4-0.40.40.6
Delay disc. indifference point, 24s delay0.40.50.7-0.8-0.80.70.9-0.7-0.70.70.3
Delay disc. indifference point, 4s delay2.72.84.5-1.4-2.01.31.3-1.7-1.81.72.1
Delay disc. indifference point, 8s delay0.20.31.3-0.4-0.50.30.5-0.3-0.30.31.1
Indifference point function ln k0.10.20.9-0.3-0.40.20.1-0.1-0.10.11.0
Indifference point function log k0.10.20.9-0.3-0.40.20.1-0.1-0.10.11.0
Patch foraging total patch changes 0 sec1.12.02.31.51.2-1.5-1.51.41.4-1.51.4
Patch foraging total patch changes 12 sec0.00.00.10.20.1-0.10.10.10.1-0.1-0.2
Patch foraging total patch changes 18 sec1.32.02.61.61.4-1.6-1.41.41.4-1.50.4
Patch foraging total patch changes 24 sec0.61.01.21.00.8-1.1-1.11.01.0-1.10.6
Patch foraging total patch changes 6 sec0.60.91.21.00.9-1.0-1.11.01.0-1.10.2
Patch foraging time to switch 0 sec0.10.10.4-0.2-0.20.20.6-0.1-0.10.2-0.6
Patch foraging water rate 0 sec1.12.23.51.61.5-1.5-1.91.51.5-1.6-0.0
Patch foraging water rate 12 sec0.20.51.60.40.4-0.7-1.00.40.3-0.41.2
Patch foraging water rate 18 sec0.00.10.1-0.0-0.10.0-0.0-0.3-0.30.30.3
Patch foraging water rate 24 sec1.01.41.91.31.3-1.4-1.21.21.2-1.2-0.8
Patch foraging water rate 6 sec0.10.21.2-0.0-0.3-0.1-0.40.00.0-0.11.1
Seeking ratio, delayed vs. immediate footshock1.82.23.71.91.9-1.7-1.61.31.3-1.3-0.5
Distance traveled before self-admin0.81.02.1-1.3-1.01.01.5-0.9-0.90.9-0.2
Distance traveled after self-admin0.10.10.2-0.00.0-0.20.10.40.4-0.40.3
Extensor digitorum longus weight0.62.43.71.91.7-1.7-1.91.51.4-1.50.3
Bone: elastic displacement0.10.10.50.20.1-0.2-0.10.40.4-0.4-0.7
Bone: elastic work0.00.00.10.10.00.00.20.10.1-0.1-0.4
Bone: endosteal estimation0.10.20.40.40.3-0.5-0.20.60.6-0.60.1
Bone: endosteal perimeter0.40.81.10.90.8-0.9-0.81.11.1-1.0-0.1
Epididymis fat weight0.31.15.30.51.0-0.6-0.30.80.7-0.7-2.3
Delta time in closed arm before/after self-admin0.20.20.70.50.8-0.5-0.50.40.3-0.3-0.3
Delta time in open arm before/after self-admin1.41.32.3-0.9-1.51.00.8-1.2-1.21.11.3
Diff in mean of infusions in LGA sessions1.11.42.2-1.5-0.81.21.1-1.2-1.11.3-1.0
Delay discount exponential model param0.50.61.80.50.9-0.5-0.60.60.7-0.6-1.3
Extinction: sum of active levers before priming0.91.01.3-1.1-1.10.91.1-1.0-1.01.00.6
Active lever presses in extinction session 60.10.10.40.30.1-0.4-0.50.30.3-0.40.6
Bone: final force0.20.30.60.60.8-0.5-0.20.60.5-0.5-0.7
Bone: final moment0.30.40.60.80.8-0.7-0.40.70.6-0.6-0.5
Food consumed during 24 hour testing period1.72.32.8-1.7-1.71.71.6-1.5-1.51.50.7
Glucose2.03.13.71.91.9-1.7-1.91.81.8-1.8-1.3
Heart weight1.42.25.61.11.7-1.4-0.61.41.4-1.2-2.4
Delay discount hyperbolic model param0.50.51.80.40.8-0.4-0.50.60.6-0.6-1.3
Intermittent access intake day 1-15 change0.10.10.5-0.2-0.70.20.10.30.3-0.4-0.0
Intermittent access intake escalation0.00.10.5-0.1-0.70.10.00.30.3-0.40.1
Intermittent access intake escalation 20.50.51.10.60.1-0.6-0.71.01.0-1.0-0.2
Intermitt. access day 1 inactive lever presses0.00.10.3-0.10.20.20.0-0.2-0.20.3-0.6
Intermitt. access day 15 inactive lever presses0.91.82.41.51.5-1.6-1.51.31.3-1.40.2
Intermitt. access escalation Index0.20.20.5-0.7-0.60.70.6-0.2-0.20.1-0.1
Intermittent access day 1 total infusions0.10.21.0-0.20.10.10.3-0.2-0.20.3-1.0
Intermittent access day 15 total infusions0.10.10.2-0.3-0.50.20.3-0.1-0.10.1-0.4
Intermittent access terminal intake (last 3 days)0.10.10.5-0.0-0.0-0.1-0.10.20.2-0.2-0.7
Intermittent access total infusions0.10.10.60.00.1-0.2-0.10.10.1-0.0-0.8
Intermittent access day 1 locomotion0.40.41.7-0.6-0.40.50.6-0.5-0.50.5-1.3
Intermittent access day 15 total locomotion0.20.31.1-0.6-0.50.40.7-0.1-0.10.2-1.0
Intermittent access total locomotion0.20.21.4-0.3-0.30.10.30.10.1-0.1-1.2
Intermittent access standard deviation0.51.11.61.00.6-1.1-1.21.21.2-1.2-0.5
Left kidney weight0.00.00.1-0.0-0.0-0.1-0.00.20.2-0.10.2
Right kidney weight0.31.41.91.11.3-1.2-1.11.41.4-1.3-0.2
Cocaine induced anxiety0.20.31.40.30.6-0.3-0.30.40.4-0.3-1.2
Post-drug Anxiety0.50.61.2-0.8-0.50.70.9-0.5-0.50.6-1.1
Baseline Anxiety1.11.32.0-1.3-1.11.11.4-1.2-1.11.10.4
Tail length18.271.094.9-9.0-9.78.98.4-8.5-8.58.35.4
Length with tail7.030.240.7-6.0-6.46.05.5-5.5-5.55.43.2
Length without tail0.10.50.80.50.7-0.6-0.60.80.7-0.7-0.9
Times rat made contact with spout0.50.61.1-1.0-0.40.90.9-0.6-0.50.6-1.0
Lifetime Intake0.00.00.10.1-0.0-0.1-0.20.10.1-0.1-0.3
Liver weight, left0.10.10.40.20.6-0.1-0.30.10.1-0.0-0.4
Liver weight, right0.10.20.7-0.4-0.50.40.4-0.4-0.40.40.9
Locomotor activity0.10.20.30.20.3-0.3-0.30.50.6-0.5-0.2
Locomotor testing distance0.51.01.40.90.9-1.0-0.91.21.2-1.10.1
Locomotor testing rearing0.10.21.50.30.1-0.3-0.10.10.1-0.11.2
Locomotion in novel chamber0.20.20.5-0.4-0.10.30.4-0.6-0.60.7-0.3
Locomotion in novel chamber post-restriction1.52.44.01.62.0-1.8-1.41.51.5-1.4-1.1
Fecal boli incidents, locomotor time 12.53.74.72.01.9-2.2-1.92.12.1-2.1-0.8
Change in fecal boli incidents, locomotor task2.32.32.9-1.7-1.21.71.7-1.6-1.61.7-0.6
Time >=10cm from walls, locomotor time 10.10.10.3-0.2-0.10.20.3-0.5-0.50.50.1
Bouts of movement, locomotor time 10.10.10.20.40.2-0.3-0.30.30.3-0.30.2
Total resting periods, locomotor time 10.40.40.60.70.6-0.7-0.70.60.6-0.6-0.1
Rest time, locomotor task time 10.20.30.50.50.4-0.5-0.70.60.6-0.6-0.1
Distance moved, locomotor task time 11.21.82.7-1.4-1.11.41.6-1.4-1.41.5-0.2
Vertical activity count, locomotor time 10.20.51.1-0.8-0.40.71.1-0.7-0.70.7-0.1
Time >=10cm from walls, locomotor time 20.30.40.7-0.7-0.30.60.7-0.8-0.80.8-0.1
Bouts of movement, locomotor time 20.00.10.30.2-0.0-0.20.10.20.2-0.10.6
Total resting periods, locomotor time 20.00.10.20.3-0.0-0.30.10.20.2-0.20.4
Rest time, locomotor task time 20.50.70.8-0.9-0.80.80.3-0.9-0.90.90.9
Distance moved, locomotor task time 20.20.20.5-0.4-0.30.40.7-0.4-0.40.4-0.6
Vertical activity count, locomotor time 20.10.20.6-0.2-0.10.20.8-0.1-0.10.1-0.8
Light reinforcement 10.00.10.20.20.3-0.3-0.10.40.5-0.50.2
Light reinforcement 20.10.20.4-0.4-0.40.40.6-0.2-0.20.2-0.5
Bone: marrow area0.10.20.30.30.2-0.4-0.10.50.5-0.50.2
Bone: maximum diameter0.50.91.21.01.1-1.0-1.01.11.1-1.1-0.3
Bone: maximum force0.50.91.41.11.2-1.1-0.81.01.0-1.0-0.4
Bone: maximum moment0.71.21.61.31.2-1.2-1.01.21.1-1.2-0.2
Mean time between licks in bursts0.51.11.91.31.4-1.4-1.10.90.9-0.90.4
Mean num. licks in bursts0.10.10.30.20.3-0.2-0.40.10.1-0.10.5
Cd content in liver0.10.10.50.00.1-0.00.10.00.00.0-0.7
Co content in liver0.00.00.4-0.10.10.10.00.00.00.0-0.6
Cu content in liver7.38.613.9-3.2-2.83.23.7-2.8-2.83.0-1.5
Fe content in liver0.91.12.6-0.8-0.70.91.6-1.0-1.11.2-0.5
K content in liver1.71.65.8-1.1-0.80.91.7-0.7-0.60.8-2.4
Mg content in liver5.96.010.5-2.6-2.22.53.2-2.3-2.32.5-1.8
Mn content in liver5.05.57.0-2.4-2.62.52.3-2.5-2.42.41.5
Na content in liver0.70.74.7-0.3-0.20.20.90.20.3-0.1-2.2
Rb content in liver0.80.91.6-1.3-0.81.01.1-0.9-0.91.0-0.0
Se content in liver0.40.51.60.60.7-0.4-0.30.60.6-0.5-1.3
Sr content in liver1.71.42.9-1.0-1.41.00.8-1.2-1.21.11.7
Zn content in liver1.01.17.5-0.40.00.40.9-0.1-0.10.3-2.7
Bone: minimum diameter0.00.10.10.20.3-0.3-0.20.30.3-0.2-0.1
Time in familiar zone, hab. session 10.20.20.4-0.2-0.20.30.6-0.6-0.60.60.2
Time in novel zone, hab. session 12.22.23.01.31.2-1.3-1.71.71.7-1.7-1.1
Total zone transitions, hab. session 16.28.610.8-3.3-2.93.12.9-3.2-3.23.20.9
Total locomotion distance, hab. session 13.65.16.2-2.5-2.32.42.4-2.4-2.32.4-0.6
Locomotion velocity, hab. session 14.56.37.9-2.8-2.52.72.8-2.7-2.62.7-0.6
Time in familiar zone, hab. session 21.01.11.71.21.3-1.1-1.31.01.0-1.00.2
Time in novel zone, hab. session 20.20.20.4-0.4-0.60.40.5-0.4-0.40.4-0.2
Total zone transitions, hab. session 23.54.46.1-2.5-2.22.32.4-2.1-2.12.10.3
Total locomotion distance, hab. session 20.81.01.6-1.2-0.91.11.2-0.8-0.80.8-1.1
Locomotion velocity, hab. session 21.01.32.0-1.4-1.01.21.4-0.9-0.91.0-1.2
Novel to familiar place preference ratio0.30.30.5-0.4-0.60.40.4-0.7-0.70.70.2
Novelty place preference0.30.30.5-0.4-0.70.30.3-0.7-0.70.70.4
Time in novel zone, NPP test0.20.20.3-0.2-0.50.20.2-0.6-0.60.60.3
Total zone transitions, NPP test5.07.28.7-2.9-2.92.92.8-2.8-2.72.71.4
Total locomotion distance, NPP test1.62.22.8-1.6-1.71.61.7-1.5-1.51.5-0.1
Locomotion velocity, NPP test2.23.13.9-1.9-1.91.92.0-1.8-1.81.8-0.0
Intraocular pressure1.31.83.2-1.2-1.41.21.2-1.4-1.41.31.8
Delta distance traveled before/after self-admin1.01.11.51.11.0-1.0-1.21.11.0-1.10.4
Delta ambulatory time before/after self-admin1.11.42.01.21.4-1.1-1.21.21.2-1.2-0.6
Parametrial fat weight0.10.31.30.40.6-0.4-0.10.50.4-0.4-1.2
Pavlov. Cond. lever latency1.21.51.71.31.3-1.3-1.01.31.3-1.3-1.2
Pavlov. Cond. magazine entry latency0.10.10.2-0.4-0.30.40.3-0.3-0.30.2-0.4
Pavlov. Cond. change in total contacts3.23.44.2-2.0-1.92.02.1-1.9-1.91.90.3
Pavlov. Cond. index score0.70.91.2-1.1-1.01.10.9-1.0-1.01.00.4
Pavlov. Cond. latency score0.70.91.2-1.1-1.01.10.9-1.0-1.01.00.6
Pavlov. Cond. lever contacts2.32.73.4-1.8-1.81.81.7-1.7-1.71.70.9
Pavlov. Cond. magazine entry number0.50.71.00.90.8-0.9-1.00.80.8-0.80.5
Pavlov. Cond. intertrial magazine entries0.91.01.6-1.2-0.91.11.3-1.0-1.01.1-0.3
Pavlov. Cond. lever-magazine prob. diff.0.70.91.1-1.0-1.01.10.9-1.0-1.00.90.4
Pavlov. Cond. response bias0.81.01.3-1.1-1.11.11.1-1.1-1.11.10.1
Pavlov. Cond. lever latency1.21.72.5-1.5-1.01.41.6-1.2-1.21.4-1.0
Pavlov. Cond. magazine entry latency0.20.20.4-0.4-0.60.60.4-0.5-0.50.40.1
Pavlov. Cond. change in total contacts0.50.82.40.80.2-0.8-0.90.70.6-0.81.6
Pavlov. Cond. index score0.30.50.60.70.4-0.7-0.80.70.7-0.80.5
Pavlov. Cond. latency score0.10.20.30.40.1-0.4-0.50.40.4-0.50.6
Pavlov. Cond. lever contacts1.11.52.21.41.0-1.3-1.51.21.2-1.31.0
Pavlov. Cond. magazine entry number0.00.00.1-0.20.00.10.2-0.2-0.20.20.1
Pavlov. Cond. intertrial magazine entries1.42.22.8-1.7-1.41.41.3-1.6-1.61.70.7
Pavlov. Cond. lever-magazine prob. diff.0.40.50.70.80.4-0.7-0.80.70.7-0.80.5
Pavlov. Cond. response bias1.01.41.91.31.0-1.3-1.41.21.2-1.30.5
Time in closed arm before self-admin2.22.93.71.91.7-1.8-1.81.71.7-1.7-1.1
Time in closed arm after self-admin3.23.45.01.92.2-1.8-1.61.71.7-1.6-2.1
Time in open arm before self-admin0.20.30.5-0.6-0.20.50.7-0.5-0.50.5-0.3
Time in open arm after self-admin2.42.63.7-1.5-1.91.51.5-1.7-1.71.61.6
Bone: periosteal estimation0.30.70.91.01.0-1.0-0.70.90.9-0.9-0.1
Bone: periosteal perimeter1.22.02.81.71.6-1.5-1.61.41.4-1.40.2
Bone: post-yield work0.60.91.61.01.0-1.0-1.30.90.9-0.90.1
Progressive ratio test 1 active lever presses0.70.81.4-1.2-1.01.11.0-0.9-0.90.80.3
Progressive ratio test 1 breakpoint0.50.61.0-1.0-0.81.00.8-0.7-0.80.70.3
Progressive ratio test 1 inactive lever presses0.30.40.80.70.9-0.7-0.90.60.6-0.6-0.1
Progressive ratio test 2 active lever presses0.50.61.2-0.8-0.60.71.0-0.6-0.60.6-1.1
Progressive ratio test 2 breakpoint0.50.61.2-0.8-0.60.71.0-0.6-0.60.7-1.1
Progressive ratio test 2 inactive lever presses0.10.21.20.20.4-0.20.00.10.10.0-1.1
Incentive Sensitization - Responses0.10.20.8-0.1-0.20.10.6-0.1-0.10.2-0.9
Incentive Sensitization - Breakpoint0.10.10.90.0-0.1-0.10.50.00.00.1-0.9
Sum of active levers in priming session hrs 5-64.03.74.5-2.1-2.02.01.7-2.0-2.02.01.6
Progressive ratio0.40.63.80.50.3-0.3-0.70.00.00.02.0
Food seeking constrained by brief footshock0.20.21.0-0.1-0.20.1-0.20.40.4-0.51.0
Seeking ratio, punishment vs. effort0.60.81.3-1.1-1.10.91.1-0.5-0.50.4-1.1
Retroperitoneal fat weight0.41.71.91.41.3-1.2-1.11.41.3-1.3-1.4
Reaction time number correct0.71.45.21.10.8-1.1-1.30.60.5-0.62.3
Reaction time mean minus median0.71.82.7-1.5-1.31.41.7-1.3-1.31.30.4
Reaction time mean minus median AUC1.02.44.1-1.8-1.41.72.0-1.5-1.61.5-0.2
Reaction time num false alarms0.81.11.9-1.4-1.31.21.0-0.9-0.90.80.2
Reaction time num false alarms AUC0.81.32.3-1.5-1.41.31.1-1.0-1.00.90.4
Reaction time trials correct on left0.71.45.21.10.8-1.1-1.30.60.5-0.62.3
Reaction time trials on left0.71.35.51.10.7-1.0-1.30.50.5-0.62.3
Reaction time mean0.71.12.4-1.0-0.51.01.5-0.7-0.80.8-1.5
Reaction time mean AUC0.81.32.8-1.1-0.61.11.6-0.8-0.80.9-1.7
Median of all reaction times0.60.94.3-0.7-0.20.71.2-0.4-0.40.4-2.1
Reaction time omissions0.91.42.3-1.5-1.21.31.2-1.1-1.11.00.5
Reaction time false alarm rate1.21.62.9-1.7-1.61.51.4-1.0-1.00.9-0.5
Reaction time premature initiation rate0.30.41.2-0.5-0.70.50.2-0.6-0.60.41.1
Reaction time premature initiations0.50.96.6-0.0-0.40.1-0.4-0.4-0.40.22.6
Std. dev. reaction times0.91.62.8-1.5-1.11.41.7-1.2-1.21.2-0.5
Reaction time trials completed0.71.35.51.10.7-1.0-1.30.50.5-0.62.3
Reaction time trials AUC0.81.46.21.10.7-1.0-1.30.50.5-0.62.5
Run reversals in cocaine runway, females0.20.20.6-0.4-0.50.30.2-0.2-0.30.20.8
Run reversals in cocaine runway, males1.51.52.41.31.5-1.3-1.31.11.1-1.1-0.9
Latency to leave start box in cocaine runway4.75.37.32.72.6-2.5-2.12.22.2-2.1-1.9
Latency to leave start box in cocaine runway, F6.67.510.53.22.9-3.0-2.92.82.8-2.8-1.1
Latency to leave start box in cocaine runway, M0.80.74.90.40.7-0.40.20.30.3-0.1-2.2
Std. dev. time between licks in bursts1.01.31.91.10.9-1.2-1.41.21.2-1.30.8
Total sessions with >9 infusions0.00.00.10.2-0.2-0.0-0.30.20.2-0.30.1
Short access day 1 total inactive lever presses1.72.29.0-0.6-1.10.80.5-1.5-1.51.43.0
Short access day 10 total inactive lever presses0.51.21.81.21.3-1.2-1.41.01.0-0.90.0
Short access day 1 total infusions0.30.42.30.4-0.4-0.1-0.50.10.1-0.31.5
Short access day 10 total infusions0.20.21.20.20.3-0.1-0.20.40.4-0.4-1.1
Short access total infusions0.20.20.50.50.1-0.4-0.70.50.5-0.50.4
Short access day 1 locomotion0.80.92.70.80.7-0.6-0.71.01.0-1.0-1.6
Short access day 10 total locomotion0.20.41.00.20.2-0.2-0.10.80.8-0.8-1.0
Short access total locomotion0.50.61.40.60.4-0.4-0.60.90.9-0.9-1.2
One hour access (0.3 mA shock)0.50.60.8-0.9-0.90.80.8-0.8-0.80.8-0.5
Compulsive drug intake2.93.54.6-2.0-1.81.91.8-2.1-2.12.10.4
One hour access (shock baseline)0.81.31.81.01.0-1.0-0.91.31.3-1.2-1.3
Social response proportion1.92.22.8-1.6-1.71.71.6-1.5-1.51.50.2
Social responses0.10.10.8-0.1-0.30.10.0-0.1-0.10.10.9
Social time0.10.20.50.40.7-0.4-0.50.30.3-0.30.2
Soleus weight1.54.34.92.12.1-2.1-2.12.22.2-2.2-1.4
Bone: stiffness0.10.10.60.30.5-0.30.20.20.2-0.1-0.8
Tibialis anterior weight0.20.63.1-0.5-0.50.60.0-0.5-0.60.41.8
Time to tail flick, vehicle, before self-admin3.13.24.9-1.8-1.51.91.8-2.1-2.12.2-0.2
Time to tail flick, vehicle, after self-admin0.70.91.71.31.0-1.2-1.00.80.8-0.80.1
Time to tail flick, test, before self-admin0.30.30.50.60.6-0.6-0.70.60.6-0.60.3
Time to tail flick, test, after self-admin0.70.71.40.90.8-1.0-1.20.80.8-0.80.3
Delta time to tail flick, vehicle, before/after SA4.94.66.02.42.0-2.4-2.42.32.2-2.30.1
Delta time to tail flick, test, before/after SA0.20.30.4-0.5-0.60.40.4-0.6-0.60.50.4
Tibia length0.61.51.81.31.2-1.3-1.31.31.3-1.30.7
Ambulatory time before self-admin0.30.51.2-0.9-0.70.61.1-0.6-0.60.6-0.2
Ambulatory time after self-admin0.10.20.30.00.2-0.40.20.50.5-0.5-0.5
Bone: tissue strength0.70.71.21.10.9-1.0-1.00.80.8-0.8-0.1
Total heroin consumption1.21.42.8-1.3-1.11.10.6-1.2-1.21.21.7
Bone: trabecular number0.50.83.00.70.7-0.6-0.40.80.9-0.8-1.7
Bone: trabecular spacing0.00.00.20.1-0.0-0.1-0.2-0.0-0.0-0.00.5
Bone: trabecular thickness3.34.15.52.31.9-2.4-2.12.12.1-2.10.7
Bone: trabecular tissue density0.20.42.6-0.2-0.30.10.1-0.2-0.20.21.6
Water consumed over 24 hours0.10.10.1-0.3-0.30.40.2-0.3-0.30.30.2
Number of responses in last shaping day1.11.21.81.21.3-1.1-1.00.90.9-0.8-1.2