LOC102550527

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA gene expression LOC102550527 0.37 0.13 1.0e-03 0.04 0.03 0.05 0.03 3.4e-03 1.0e-02 1.4e-03 6.2e-03
2 Brain mRNA stability LOC102550527 0.03 0.03 9.9e-03 0.01 0 0 0 4.0e-02 1.4e-01 2.4e-01 1.2e-01
3 Adipose isoform ratio XR_010057176.1 0.09 0.08 3.4e-10 0.07 0.08 0.07 0.08 1.3e-08 5.9e-09 1.4e-08 5.7e-09
4 BLA intron excision ratio chr13_109046751_109051939 0.1 0.13 2.7e-03 0.07 0.02 0.05 0.06 1.2e-04 3.5e-02 1.7e-03 3.9e-04
5 Brain intron excision ratio chr13_109080982_109083310 0.36 0.24 0.0e+00 0.26 0.27 0.24 0.25 3.9e-24 4.8e-25 1.6e-22 2.2e-23
6 NAcc isoform ratio XR_010057176.1 0.02 0.02 1.2e-04 0.01 0.02 0.02 0.02 3.1e-03 1.1e-04 9.2e-04 1.5e-03
7 IC gene expression LOC102550527 0.08 0.08 6.5e-03 0.03 0.03 0.01 0.03 2.0e-02 1.7e-02 1.0e-01 2.3e-02
8 BLA intron excision ratio chr13_109046751_109065047 0.09 0.1 2.7e-03 0.02 0.02 0.02 0.01 2.4e-02 2.6e-02 4.3e-02 5.9e-02
9 NAcc isoform ratio XR_010057180.1 0.04 0.06 8.4e-04 0.02 0.01 0.02 0.02 3.1e-04 2.5e-03 1.0e-03 1.6e-03
10 Adipose isoform ratio XR_359266.5 0.03 0.03 1.7e-03 0.02 0.01 0.01 0.01 4.1e-03 9.5e-03 2.9e-02 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.00.10.20.2-0.2-0.2-0.1-0.2-0.2-0.20.10.40.3
Area under the delay curve0.30.31.0-0.60.50.11.00.40.40.4-0.2-0.4-0.9
BMI with tail0.10.20.50.0-0.4-0.40.5-0.4-0.4-0.40.40.70.3
BMI without tail0.92.93.8-1.2-1.7-1.71.5-1.7-1.8-1.81.92.01.7
Body weight3.414.819.5-3.9-3.9-3.84.4-3.8-3.8-3.84.03.83.3
Weight adjusted by age1.92.93.5-1.5-1.8-1.91.5-1.9-1.8-1.81.71.81.5
Bone surface0.61.11.8-0.7-1.2-1.00.7-1.0-1.0-1.01.21.31.2
Bone volume0.30.50.9-0.5-0.8-0.70.6-0.7-0.7-0.70.80.90.9
Breakpoint value in progressive ratio session3.34.05.1-1.5-2.0-2.01.6-2.1-2.1-2.12.02.32.0
Number of licking bursts0.10.20.70.2-0.2-0.20.0-0.2-0.3-0.30.30.60.8
Context. condit. distance diff. score0.20.30.8-0.9-0.6-0.50.4-0.5-0.5-0.40.60.30.1
Locomotion velocity, session 13.53.85.7-1.3-2.0-1.91.3-2.0-2.0-2.11.82.42.4
Locomotion distance, session 13.34.25.6-1.5-2.1-2.01.6-2.1-2.1-2.12.02.32.4
Locomotion velocity, session 21.11.32.1-0.5-1.1-1.20.6-1.2-1.2-1.20.91.41.4
Locomotion distance, session 22.12.96.3-0.0-1.6-1.60.9-1.7-1.7-1.81.22.52.5
Locomotion velocity, session 31.51.72.5-1.4-1.3-1.21.6-1.2-1.3-1.21.21.41.3
Locomotion distance, session 30.00.10.20.40.00.20.10.20.10.1-0.00.30.4
Stereotopy head waving bouts, day 32.73.26.5-0.7-1.7-1.71.3-1.7-1.8-1.81.42.42.5
Stereotopy head waving duration, day 32.02.44.1-0.9-1.6-1.61.2-1.6-1.6-1.61.21.92.0
Locomotion velocity, session 70.00.00.0-0.0-0.1-0.2-0.0-0.2-0.2-0.2-0.1-0.0-0.0
Locomotion distance, session 70.50.62.11.40.40.4-1.50.40.40.4-0.8-0.1-0.3
Stereotopy head waving bouts, day 71.92.14.7-2.2-1.4-1.22.1-1.2-1.2-1.21.41.21.2
Stereotopy head waving duration, day 71.21.43.7-1.9-1.0-0.91.9-0.9-1.0-0.91.10.80.9
Locomotion velocity, session 80.40.51.20.0-0.6-0.60.1-0.7-0.7-0.80.61.01.1
Locomotion distance, session 81.72.43.0-1.4-1.7-1.61.1-1.7-1.6-1.61.51.71.5
Degree of sensitization distance0.50.52.11.10.50.3-1.40.30.40.4-0.7-0.4-0.6
Degree of sensitization stereotypy0.30.31.7-1.3-0.00.11.10.10.10.10.2-0.3-0.3
Conditioned locomotion0.60.61.00.90.70.8-1.00.70.70.7-0.8-0.8-0.8
Cocaine response after cond. corrected0.20.30.8-0.40.60.60.20.60.50.6-0.4-0.9-0.4
Cocaine response after cond. not corrected0.10.10.3-0.40.40.40.40.40.30.3-0.3-0.50.1
Cocaine response before conditioning0.20.20.90.1-0.4-0.30.2-0.3-0.4-0.40.30.71.0
Saline control response1.01.32.51.61.11.2-1.21.21.11.1-1.0-0.6-0.7
Bone: connectivity density0.30.50.9-0.5-0.9-0.70.2-0.7-0.8-0.70.90.80.7
Bone: cortical apparent density0.10.10.20.10.20.2-0.40.20.20.2-0.1-0.5-0.3
Bone: cortical area1.42.12.4-1.5-1.5-1.51.2-1.5-1.5-1.51.51.31.4
Bone: cortical porosity0.20.21.01.00.50.3-0.30.40.30.3-0.50.20.2
Bone: cortical porosity0.30.31.21.10.60.5-0.50.60.50.5-0.7-0.00.0
Bone: cortical thickness0.71.21.7-1.3-1.2-1.20.7-1.2-1.1-1.11.10.80.9
Bone: cortical thickness3.13.64.5-1.4-2.1-2.11.0-2.1-2.0-2.01.92.12.0
Bone: cortical tissue density0.10.10.20.20.30.2-0.40.30.30.3-0.2-0.5-0.3
Condit. Reinf. active minus inactive responses0.10.10.4-0.6-0.2-0.20.0-0.2-0.1-0.20.1-0.4-0.3
Condit. Reinf. active-inactive response ratio1.21.32.30.51.11.0-1.01.01.11.1-1.1-1.5-1.4
Condit. Reinf. active responses0.60.81.2-1.1-1.0-0.90.7-1.0-0.9-0.90.80.70.6
Condit. Reinf. inactive responses2.42.94.5-1.2-1.8-1.71.3-1.8-1.8-1.81.62.11.9
Incentive salience index mean0.20.20.5-0.7-0.5-0.50.3-0.5-0.4-0.50.30.10.2
Condit. Reinf. lever presses0.60.81.1-0.9-1.1-1.00.7-1.0-1.0-0.90.81.00.9
Condit. Reinf. active minus inactive responses0.50.62.31.50.60.5-1.30.50.50.5-0.9-0.2-0.1
Condit. Reinf. active-inactive response ratio0.81.01.41.00.90.9-1.20.90.90.9-1.2-0.9-0.9
Condit. Reinf. active responses0.10.10.80.90.10.0-0.60.00.00.0-0.30.20.3
Condit. Reinf. inactive responses0.81.01.3-0.7-1.0-1.00.9-1.0-1.0-1.01.01.11.1
Condit. Reinf. lever presses0.60.82.30.2-0.7-0.90.4-0.8-0.9-0.90.51.21.5
Condit. Reinf. lever reinforcers received0.10.10.40.7-0.0-0.1-0.4-0.1-0.1-0.1-0.20.30.4
Conditioned reinforcement - actives0.61.02.5-1.6-1.0-1.20.9-1.0-1.0-0.91.10.40.5
Conditioned reinforcement - inactives3.65.37.5-2.7-2.6-2.71.9-2.5-2.4-2.42.31.71.7
Conditioned locomotion2.83.65.2-2.1-1.9-2.31.7-2.0-2.0-1.91.81.51.5
Patch foraging indifference point 0 sec0.40.71.7-1.3-0.9-0.81.0-0.7-0.7-0.70.90.40.5
Patch foraging indifference point AUC0.91.22.31.51.01.0-1.30.90.90.9-1.2-0.9-1.2
Delay disc. indifference point, 0s delay1.92.13.0-1.0-1.4-1.71.6-1.6-1.5-1.51.21.71.2
Delay disc. indifference point, 16s delay0.60.61.40.51.20.8-0.30.90.90.9-0.5-0.7-0.9
Delay disc. indifference point, 2s delay0.20.21.3-0.2-0.0-0.41.1-0.1-0.1-0.1-0.10.40.1
Delay disc. indifference point, 24s delay2.93.36.5-0.61.91.8-0.12.02.02.0-1.0-2.5-2.5
Delay disc. indifference point, 4s delay0.30.32.2-0.80.0-0.11.50.10.10.10.30.4-0.2
Delay disc. indifference point, 8s delay0.30.41.1-0.20.60.20.60.50.50.5-0.6-0.6-1.1
Indifference point function ln k1.73.04.9-1.3-1.6-1.61.9-1.5-1.6-1.61.82.02.2
Indifference point function log k1.73.04.9-1.3-1.6-1.61.9-1.5-1.6-1.61.82.02.2
Patch foraging total patch changes 0 sec0.30.50.7-0.8-0.8-0.70.7-0.6-0.6-0.60.80.60.7
Patch foraging total patch changes 12 sec0.30.41.1-0.3-0.6-0.70.3-0.8-0.8-0.80.30.41.0
Patch foraging total patch changes 18 sec0.40.71.0-0.4-1.0-1.00.5-1.0-0.9-1.00.60.90.6
Patch foraging total patch changes 24 sec0.00.10.2-0.3-0.4-0.30.2-0.3-0.3-0.30.10.00.2
Patch foraging total patch changes 6 sec0.00.00.2-0.3-0.2-0.00.4-0.1-0.1-0.1-0.1-0.1-0.1
Patch foraging time to switch 0 sec0.91.87.0-2.6-1.2-1.11.7-1.0-1.0-0.91.40.30.5
Patch foraging water rate 0 sec0.61.36.92.60.80.8-1.50.70.60.5-1.10.20.4
Patch foraging water rate 12 sec0.61.25.12.30.90.7-1.70.80.70.7-1.2-0.1-0.4
Patch foraging water rate 18 sec0.20.30.90.5-0.5-0.50.2-0.5-0.5-0.60.20.90.9
Patch foraging water rate 24 sec0.30.41.30.7-0.4-0.60.2-0.5-0.5-0.60.31.11.0
Patch foraging water rate 6 sec0.71.05.22.30.0-0.0-0.9-0.1-0.3-0.3-0.21.41.3
Seeking ratio, delayed vs. immediate footshock3.44.27.22.71.92.0-2.41.81.81.8-2.2-1.7-1.9
Distance traveled before self-admin1.72.33.4-1.2-1.5-1.71.1-1.8-1.7-1.81.31.41.3
Distance traveled after self-admin3.24.05.6-1.7-2.2-2.11.7-2.4-2.2-2.31.71.81.5
Extensor digitorum longus weight0.00.10.3-0.3-0.4-0.30.3-0.3-0.3-0.30.30.50.4
Bone: elastic displacement0.10.10.2-0.3-0.2-0.50.3-0.4-0.3-0.40.30.20.3
Bone: elastic work0.30.40.5-0.4-0.5-0.70.5-0.7-0.7-0.70.60.60.7
Bone: endosteal estimation0.00.10.4-0.6-0.1-0.00.6-0.0-0.1-0.00.2-0.0-0.0
Bone: endosteal perimeter0.10.20.5-0.7-0.4-0.30.6-0.3-0.3-0.30.50.20.3
Epididymis fat weight0.51.62.8-1.1-1.2-1.11.7-1.1-1.2-1.21.11.51.5
Delta time in closed arm before/after self-admin0.00.00.2-0.10.00.0-0.00.10.00.10.40.20.4
Delta time in open arm before/after self-admin0.20.20.60.10.40.1-0.60.20.30.3-0.4-0.7-0.8
Diff in mean of infusions in LGA sessions0.70.91.3-1.0-0.9-1.10.6-1.1-1.1-1.01.00.90.5
Delay discount exponential model param0.40.41.00.5-0.7-0.3-0.9-0.6-0.6-0.60.40.61.0
Extinction: sum of active levers before priming5.66.28.3-2.5-2.5-2.51.8-2.7-2.7-2.72.92.22.2
Active lever presses in extinction session 612.812.818.1-4.3-3.7-3.83.1-3.7-3.6-3.63.93.02.7
Bone: final force0.81.32.7-1.7-1.1-1.01.6-1.0-1.0-1.01.00.80.8
Bone: final moment0.91.43.1-1.8-1.2-1.01.6-1.0-1.1-1.01.10.80.8
Food consumed during 24 hour testing period1.11.53.8-0.7-1.0-1.01.3-1.0-1.1-1.11.41.41.9
Glucose0.30.50.70.80.90.8-0.40.80.70.7-0.7-0.6-0.3
Heart weight0.91.41.7-0.8-1.1-1.21.2-1.3-1.3-1.31.21.31.2
Delay discount hyperbolic model param0.20.31.10.6-0.4-0.1-1.0-0.3-0.3-0.40.10.30.7
Intermittent access intake day 1-15 change0.00.10.1-0.00.20.2-0.10.20.20.2-0.3-0.4-0.4
Intermittent access intake escalation0.10.10.3-0.10.20.3-0.20.30.40.4-0.3-0.5-0.5
Intermittent access intake escalation 20.00.00.00.10.10.1-0.00.10.10.1-0.2-0.00.0
Intermitt. access day 1 inactive lever presses0.10.40.7-0.6-0.7-0.80.4-0.6-0.6-0.60.40.50.8
Intermitt. access day 15 inactive lever presses0.40.71.3-1.0-1.1-1.10.8-0.9-0.8-0.80.70.60.4
Intermitt. access escalation Index1.01.52.11.21.21.3-1.51.21.21.2-1.1-1.2-1.1
Intermittent access day 1 total infusions1.52.43.2-1.8-1.6-1.61.5-1.6-1.6-1.61.61.31.2
Intermittent access day 15 total infusions0.60.82.4-1.6-0.9-1.00.8-0.9-0.8-0.81.00.30.2
Intermittent access terminal intake (last 3 days)1.41.83.2-1.8-1.4-1.51.2-1.4-1.4-1.31.40.90.9
Intermittent access total infusions0.91.12.4-1.6-1.0-1.20.9-1.0-1.0-1.01.10.50.5
Intermittent access day 1 locomotion2.83.54.0-2.0-1.9-2.01.8-2.0-2.0-1.91.91.71.6
Intermittent access day 15 total locomotion2.85.16.0-2.4-2.4-2.52.0-2.4-2.4-2.32.21.92.0
Intermittent access total locomotion2.52.94.2-2.1-1.7-1.91.6-1.7-1.7-1.71.81.41.5
Intermittent access standard deviation0.20.41.2-1.1-0.7-0.81.0-0.6-0.5-0.50.5-0.0-0.0
Left kidney weight1.99.014.7-3.8-3.1-2.83.5-2.9-2.9-2.83.12.52.4
Right kidney weight3.415.620.1-4.3-4.0-3.74.5-3.8-3.8-3.84.13.73.7
Cocaine induced anxiety0.60.81.1-0.8-1.0-1.00.7-1.0-1.0-1.01.00.80.6
Post-drug Anxiety0.20.20.3-0.5-0.6-0.50.1-0.6-0.5-0.50.30.20.1
Baseline Anxiety2.32.63.51.21.51.6-1.71.61.61.6-1.7-1.9-1.7
Tail length2.49.412.0-3.5-3.2-2.83.2-3.0-3.0-3.03.42.82.7
Length with tail5.222.527.7-5.2-4.8-4.65.3-4.7-4.7-4.74.94.44.2
Length without tail2.89.113.7-3.3-2.9-2.93.7-2.8-2.9-2.93.12.92.7
Times rat made contact with spout0.20.30.9-0.3-0.3-0.40.8-0.3-0.4-0.40.50.61.0
Lifetime Intake1.21.53.0-1.7-1.2-1.41.1-1.2-1.2-1.21.30.70.7
Liver weight, left0.71.22.0-1.4-1.2-1.21.1-1.2-1.1-1.11.10.80.9
Liver weight, right0.10.31.6-1.3-0.1-0.10.80.00.00.00.3-0.4-0.3
Locomotor activity1.62.43.5-1.3-1.4-1.61.8-1.5-1.5-1.61.41.61.9
Locomotor testing distance0.81.52.1-0.9-1.3-1.30.9-1.3-1.3-1.31.11.21.4
Locomotor testing rearing0.20.30.90.8-0.5-0.3-0.9-0.4-0.4-0.40.00.50.8
Locomotion in novel chamber0.60.81.90.60.80.8-0.40.80.80.8-0.9-1.0-1.4
Locomotion in novel chamber post-restriction0.50.81.60.90.51.0-0.90.90.90.9-0.6-0.8-1.3
Fecal boli incidents, locomotor time 10.70.91.60.80.91.1-1.10.90.90.9-1.0-1.3-0.7
Change in fecal boli incidents, locomotor task0.30.30.8-0.2-0.5-0.90.7-0.7-0.6-0.60.20.60.2
Time >=10cm from walls, locomotor time 10.30.30.60.4-0.3-0.7-0.4-0.7-0.7-0.70.50.70.4
Bouts of movement, locomotor time 11.41.63.2-0.51.41.4-0.21.21.31.3-0.8-1.8-1.7
Total resting periods, locomotor time 11.31.52.8-0.31.31.4-0.31.31.31.3-0.7-1.7-1.6
Rest time, locomotor task time 10.00.10.1-0.20.00.2-0.00.30.20.3-0.4-0.40.2
Distance moved, locomotor task time 11.72.54.8-0.7-1.5-1.71.7-1.6-1.6-1.71.62.21.2
Vertical activity count, locomotor time 10.00.10.8-0.00.10.10.50.10.10.10.20.1-0.9
Time >=10cm from walls, locomotor time 20.50.82.2-0.1-0.7-0.70.6-0.7-0.8-0.81.01.51.0
Bouts of movement, locomotor time 20.50.82.4-0.21.10.8-0.30.90.90.9-0.4-1.3-1.6
Total resting periods, locomotor time 20.30.51.6-0.60.80.6-0.00.60.60.6-0.1-1.0-1.3
Rest time, locomotor task time 20.60.82.2-0.50.70.8-0.60.90.91.0-0.7-1.5-0.8
Distance moved, locomotor task time 23.23.86.7-1.0-2.0-2.01.9-2.0-2.0-2.01.82.61.8
Vertical activity count, locomotor time 20.40.51.2-0.5-0.7-0.91.1-0.8-0.7-0.80.60.80.1
Light reinforcement 10.10.10.30.50.30.5-0.20.40.40.4-0.4-0.1-0.1
Light reinforcement 20.10.10.30.10.30.20.40.30.30.3-0.3-0.1-0.5
Bone: marrow area0.00.10.3-0.5-0.00.10.50.10.10.10.1-0.1-0.1
Bone: maximum diameter0.40.81.0-1.0-0.9-0.90.9-0.9-0.9-0.90.90.80.9
Bone: maximum force1.62.93.6-1.9-1.7-1.71.8-1.6-1.7-1.71.81.51.6
Bone: maximum moment1.93.34.3-2.1-1.9-1.81.9-1.8-1.8-1.81.91.51.7
Mean time between licks in bursts0.00.00.20.40.1-0.1-0.3-0.1-0.1-0.1-0.30.10.1
Mean num. licks in bursts0.00.00.1-0.3-0.1-0.10.3-0.1-0.1-0.00.10.0-0.0
Cd content in liver3.84.24.6-1.8-2.1-2.11.9-2.1-2.1-2.12.02.12.1
Co content in liver0.60.71.5-0.0-0.8-0.80.4-0.8-0.9-0.90.61.11.2
Cu content in liver5.26.17.32.62.72.6-2.02.62.62.6-2.5-2.2-2.2
Fe content in liver5.16.27.12.52.72.6-1.92.72.62.6-2.6-2.4-2.1
K content in liver0.70.60.80.80.90.8-0.70.80.80.8-0.8-0.7-0.8
Mg content in liver0.20.20.3-0.2-0.4-0.40.2-0.4-0.4-0.40.40.40.5
Mn content in liver0.10.10.20.4-0.2-0.2-0.4-0.2-0.2-0.30.30.40.4
Na content in liver2.42.63.31.81.81.8-1.41.81.71.7-1.5-1.3-1.2
Rb content in liver0.60.71.11.00.70.7-1.00.80.80.8-1.0-0.7-0.5
Se content in liver0.20.30.5-0.4-0.5-0.70.4-0.7-0.6-0.70.50.30.3
Sr content in liver0.50.42.31.50.60.5-0.60.50.40.3-0.60.30.6
Zn content in liver4.24.65.4-1.8-2.2-2.22.0-2.2-2.2-2.22.12.32.2
Bone: minimum diameter0.00.00.1-0.0-0.2-0.2-0.2-0.2-0.2-0.20.20.10.1
Time in familiar zone, hab. session 10.10.10.20.40.20.2-0.30.20.20.2-0.3-0.0-0.1
Time in novel zone, hab. session 13.03.03.4-1.5-1.8-1.81.5-1.8-1.8-1.81.71.61.8
Total zone transitions, hab. session 14.15.77.4-2.0-2.5-2.42.2-2.4-2.4-2.42.42.72.5
Total locomotion distance, hab. session 14.36.17.3-2.2-2.5-2.42.5-2.4-2.4-2.42.52.72.5
Locomotion velocity, hab. session 12.13.03.7-1.7-1.7-1.61.9-1.6-1.7-1.61.81.91.7
Time in familiar zone, hab. session 20.40.50.6-0.5-0.7-0.70.3-0.7-0.7-0.70.80.80.7
Time in novel zone, hab. session 20.00.00.1-0.10.10.10.30.10.10.0-0.1-0.00.1
Total zone transitions, hab. session 21.72.12.5-1.5-1.5-1.41.6-1.5-1.5-1.51.31.51.4
Total locomotion distance, hab. session 22.12.73.1-1.6-1.7-1.61.7-1.6-1.6-1.61.51.81.7
Locomotion velocity, hab. session 21.31.72.1-1.2-1.3-1.31.4-1.3-1.3-1.31.21.41.4
Novel to familiar place preference ratio0.30.40.70.00.60.7-0.40.60.60.7-0.4-0.8-0.8
Novelty place preference0.10.10.3-0.10.30.4-0.30.40.40.4-0.2-0.5-0.5
Time in novel zone, NPP test0.10.10.2-0.10.20.3-0.20.30.30.3-0.1-0.4-0.5
Total zone transitions, NPP test3.65.26.0-2.0-2.3-2.32.0-2.3-2.3-2.42.22.42.4
Total locomotion distance, NPP test2.33.13.6-1.6-1.9-1.81.6-1.8-1.8-1.81.71.91.7
Locomotion velocity, NPP test2.33.24.0-1.5-1.9-1.81.6-1.8-1.8-1.81.82.01.9
Intraocular pressure0.00.00.0-0.1-0.0-0.00.2-0.00.0-0.0-0.1-0.1-0.2
Delta distance traveled before/after self-admin0.10.10.2-0.4-0.5-0.20.4-0.3-0.3-0.30.20.40.2
Delta ambulatory time before/after self-admin0.10.10.4-0.20.20.5-0.20.40.40.4-0.3-0.5-0.6
Parametrial fat weight0.10.20.6-0.8-0.2-0.30.7-0.3-0.3-0.20.4-0.10.3
Pavlov. Cond. lever latency0.10.10.40.20.40.3-0.20.30.30.3-0.1-0.7-0.5
Pavlov. Cond. magazine entry latency1.01.32.1-1.0-1.1-1.01.1-1.0-1.1-1.11.11.41.5
Pavlov. Cond. change in total contacts0.10.20.70.3-0.2-0.00.1-0.1-0.2-0.20.10.90.8
Pavlov. Cond. index score0.00.00.20.1-0.10.1-0.00.0-0.0-0.0-0.10.50.4
Pavlov. Cond. latency score0.00.00.20.2-0.00.1-0.00.10.00.1-0.10.50.4
Pavlov. Cond. lever contacts0.00.10.30.1-0.2-0.10.1-0.1-0.1-0.1-0.10.50.4
Pavlov. Cond. magazine entry number0.91.12.10.81.00.9-1.00.91.01.0-0.9-1.4-1.4
Pavlov. Cond. intertrial magazine entries0.00.00.1-0.1-0.0-0.1-0.2-0.2-0.1-0.1-0.1-0.3-0.4
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.3-0.4-0.30.4-0.3-0.4-0.30.20.70.7
Pavlov. Cond. response bias1.31.62.5-1.0-1.3-1.21.1-1.2-1.2-1.21.11.61.5
Pavlov. Cond. lever latency1.62.24.60.81.41.5-1.21.41.51.5-1.3-1.8-2.1
Pavlov. Cond. magazine entry latency0.40.51.6-0.1-0.6-0.60.3-0.6-0.7-0.70.50.91.3
Pavlov. Cond. change in total contacts0.10.20.70.80.30.3-0.70.30.30.3-0.4-0.00.3
Pavlov. Cond. index score0.91.23.2-0.4-1.0-1.00.7-1.0-1.1-1.10.91.41.8
Pavlov. Cond. latency score0.81.03.1-0.2-0.9-0.90.6-0.9-1.0-1.00.81.31.8
Pavlov. Cond. lever contacts1.62.24.6-0.8-1.4-1.51.1-1.5-1.5-1.51.31.72.1
Pavlov. Cond. magazine entry number0.10.10.5-0.20.40.30.20.40.40.4-0.1-0.5-0.7
Pavlov. Cond. intertrial magazine entries0.30.51.20.10.80.60.30.60.70.7-0.7-0.7-1.1
Pavlov. Cond. lever-magazine prob. diff.0.70.92.7-0.2-0.9-0.90.5-0.9-0.9-1.00.81.21.6
Pavlov. Cond. response bias1.41.93.7-0.8-1.3-1.41.1-1.4-1.4-1.41.01.61.9
Time in closed arm before self-admin0.10.20.60.80.50.50.10.40.30.3-0.50.00.1
Time in closed arm after self-admin0.30.31.50.0-0.3-0.10.8-0.2-0.4-0.40.40.81.2
Time in open arm before self-admin0.50.50.8-0.9-0.8-0.60.5-0.7-0.7-0.70.90.80.7
Time in open arm after self-admin0.10.20.3-0.5-0.4-0.5-0.3-0.5-0.3-0.30.3-0.2-0.4
Bone: periosteal estimation0.61.22.3-1.5-1.1-1.01.3-1.0-1.0-1.01.10.80.9
Bone: periosteal perimeter0.71.21.3-1.1-1.1-1.01.1-1.0-1.1-1.11.11.11.2
Bone: post-yield work0.10.20.30.0-0.4-0.40.2-0.4-0.4-0.40.40.60.6
Progressive ratio test 1 active lever presses2.32.84.0-2.0-1.7-1.81.7-1.6-1.6-1.61.71.51.5
Progressive ratio test 1 breakpoint2.43.03.6-1.9-1.7-1.81.7-1.7-1.7-1.71.71.61.6
Progressive ratio test 1 inactive lever presses1.62.32.9-1.7-1.6-1.71.2-1.5-1.5-1.51.51.31.6
Progressive ratio test 2 active lever presses1.51.72.6-1.6-1.5-1.51.2-1.4-1.3-1.31.21.01.0
Progressive ratio test 2 breakpoint1.41.62.5-1.6-1.4-1.41.2-1.3-1.2-1.21.10.90.9
Progressive ratio test 2 inactive lever presses3.86.27.6-2.2-2.5-2.72.4-2.6-2.5-2.62.32.52.6
Incentive Sensitization - Responses1.31.82.5-1.5-1.6-1.51.0-1.4-1.4-1.41.41.11.1
Incentive Sensitization - Breakpoint1.21.52.1-1.4-1.5-1.40.9-1.3-1.2-1.21.30.91.0
Sum of active levers in priming session hrs 5-66.05.67.6-2.5-2.6-2.81.7-2.6-2.5-2.42.52.11.8
Progressive ratio0.30.41.20.2-0.7-0.30.4-0.7-0.7-0.80.20.91.1
Food seeking constrained by brief footshock1.01.31.61.21.21.2-1.11.31.21.2-1.0-0.9-0.8
Seeking ratio, punishment vs. effort0.50.82.0-0.01.00.5-0.61.01.01.0-0.3-1.0-1.4
Retroperitoneal fat weight1.45.910.6-3.3-2.3-2.32.9-2.2-2.2-2.22.81.91.8
Reaction time number correct1.02.05.52.31.21.3-1.91.31.21.2-1.4-0.7-0.7
Reaction time mean minus median0.20.61.10.30.90.90.00.80.80.8-0.6-0.8-1.0
Reaction time mean minus median AUC0.20.60.80.30.90.90.10.80.80.8-0.7-0.8-0.9
Reaction time num false alarms3.44.95.62.12.42.3-2.02.32.32.3-2.3-2.2-1.8
Reaction time num false alarms AUC2.13.33.91.82.02.0-1.51.91.91.9-1.9-1.8-1.5
Reaction time trials correct on left1.02.05.52.31.21.3-1.91.31.21.2-1.4-0.7-0.7
Reaction time trials on left1.12.05.52.41.31.3-1.91.31.21.2-1.4-0.7-0.7
Reaction time mean0.10.10.6-0.40.40.30.80.30.20.20.1-0.3-0.3
Reaction time mean AUC0.10.20.4-0.10.60.50.40.50.50.5-0.2-0.5-0.6
Median of all reaction times0.10.10.8-0.60.20.00.90.10.00.10.3-0.1-0.1
Reaction time omissions0.50.81.50.40.90.9-0.50.90.90.9-0.6-1.1-1.2
Reaction time false alarm rate0.40.50.90.10.90.8-0.10.80.80.8-0.7-0.9-0.7
Reaction time premature initiation rate0.91.21.7-1.3-1.2-1.20.9-1.0-1.0-1.01.21.11.0
Reaction time premature initiations0.10.10.30.3-0.3-0.3-0.2-0.2-0.2-0.30.30.60.4
Std. dev. reaction times0.10.21.2-0.60.20.11.10.10.00.10.2-0.1-0.2
Reaction time trials completed1.12.05.52.41.31.3-1.91.31.21.2-1.4-0.7-0.7
Reaction time trials AUC1.22.46.52.61.41.5-2.01.41.31.3-1.5-0.8-0.8
Run reversals in cocaine runway, females0.40.40.90.2-0.4-0.50.8-0.6-0.5-0.60.11.00.8
Run reversals in cocaine runway, males0.10.10.2-0.1-0.1-0.30.5-0.1-0.1-0.10.20.30.1
Latency to leave start box in cocaine runway2.12.42.81.11.41.6-1.61.61.61.6-1.5-1.7-1.6
Latency to leave start box in cocaine runway, F0.80.91.20.60.81.0-1.11.01.01.0-0.9-1.1-0.6
Latency to leave start box in cocaine runway, M1.31.22.60.91.01.0-0.91.11.11.1-1.2-1.1-1.6
Std. dev. time between licks in bursts0.40.51.30.7-0.6-0.6-0.1-0.6-0.7-0.70.31.11.0
Total sessions with >9 infusions2.32.85.2-2.3-1.6-1.71.7-1.6-1.6-1.61.81.11.3
Short access day 1 total inactive lever presses2.33.16.7-2.6-1.6-1.62.2-1.4-1.5-1.42.01.41.4
Short access day 10 total inactive lever presses0.00.00.30.1-0.2-0.1-0.2-0.1-0.0-0.0-0.1-0.1-0.5
Short access day 1 total infusions0.81.12.4-1.6-1.0-1.21.0-1.0-1.0-0.91.20.60.5
Short access day 10 total infusions0.91.12.5-1.6-1.0-1.11.2-1.0-1.0-1.01.20.60.6
Short access total infusions1.72.14.3-2.1-1.5-1.61.4-1.5-1.4-1.41.60.90.9
Short access day 1 locomotion0.20.20.4-0.6-0.4-0.40.3-0.4-0.4-0.40.60.20.5
Short access day 10 total locomotion0.20.41.1-0.30.50.40.10.60.60.7-0.6-1.0-1.0
Short access total locomotion0.50.61.9-1.4-0.7-0.81.0-0.7-0.7-0.70.70.30.5
One hour access (0.3 mA shock)1.11.21.7-0.8-1.2-1.30.8-1.3-1.2-1.31.01.10.9
Compulsive drug intake0.30.40.90.90.60.7-0.50.60.60.6-0.7-0.4-0.2
One hour access (shock baseline)0.50.82.1-1.4-0.9-0.80.9-0.9-0.8-0.80.90.40.4
Social response proportion0.80.91.40.71.11.1-0.91.21.11.1-0.6-0.9-0.4
Social responses2.43.15.32.31.81.8-2.31.81.71.7-1.5-1.4-0.8
Social time0.20.31.10.40.40.5-1.00.60.50.6-0.4-0.6-0.4
Soleus weight1.44.17.22.72.22.1-2.12.12.02.0-2.2-1.4-1.3
Bone: stiffness1.32.23.1-1.2-1.4-1.31.6-1.3-1.4-1.41.51.71.7
Tibialis anterior weight0.10.40.7-0.6-0.7-0.60.6-0.6-0.6-0.60.60.80.8
Time to tail flick, vehicle, before self-admin0.20.20.50.10.40.30.20.30.40.4-0.4-0.5-0.7
Time to tail flick, vehicle, after self-admin1.11.52.4-1.5-1.2-1.21.4-1.2-1.2-1.21.41.00.7
Time to tail flick, test, before self-admin1.51.62.2-0.8-1.3-1.11.0-1.4-1.4-1.41.31.31.5
Time to tail flick, test, after self-admin2.12.24.6-2.1-1.4-1.61.7-1.4-1.4-1.41.50.81.0
Delta time to tail flick, vehicle, before/after SA1.81.84.1-2.0-1.3-1.31.3-1.3-1.2-1.21.60.90.7
Delta time to tail flick, test, before/after SA0.40.42.4-1.5-0.1-0.30.80.10.10.20.4-0.7-0.6
Tibia length0.61.82.5-1.6-1.4-1.31.2-1.4-1.4-1.41.41.11.0
Ambulatory time before self-admin0.40.61.2-0.1-0.7-0.90.5-1.1-1.0-1.10.50.80.7
Ambulatory time after self-admin0.30.40.8-0.4-0.8-0.70.6-0.9-0.8-0.80.30.40.1
Bone: tissue strength2.22.23.6-1.9-1.4-1.51.9-1.5-1.5-1.51.40.91.2
Total heroin consumption4.25.06.3-2.0-2.1-2.52.2-2.4-2.4-2.42.12.21.9
Bone: trabecular number0.10.10.30.50.20.2-0.50.20.20.2-0.2-0.1-0.2
Bone: trabecular spacing2.63.55.2-2.3-1.9-1.92.0-1.9-1.9-1.91.91.41.6
Bone: trabecular thickness0.40.51.11.10.60.5-0.90.60.70.7-0.8-0.4-0.6
Bone: trabecular tissue density0.20.30.40.50.60.6-0.00.60.60.6-0.6-0.2-0.2
Water consumed over 24 hours0.40.52.30.1-0.5-0.40.5-0.4-0.5-0.50.61.11.5
Number of responses in last shaping day0.30.30.60.50.60.3-0.30.40.50.5-0.8-0.7-0.7