Hub : Genes

LOC102550499

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC102550499 0.23 0.13 3.2e-05 0.13 0.11 0.14 0.11 5.3e-04 1.4e-03 3.9e-04 1.3e-03
2 Liver gene expression LOC102550499 0.03 0.02 1.4e-03 0.02 0.01 0.01 0.01 2.8e-03 1.0e-02 7.4e-03 1.1e-02
3 PL gene expression LOC102550499 0.05 0.03 1.3e-07 0.06 0.06 0.06 0.06 1.1e-06 6.3e-07 3.6e-07 7.1e-07
4 BLA gene expression LOC102550499 0.07 0.05 1.2e-03 0.04 0.05 0.04 0.02 5.2e-03 1.7e-03 5.6e-03 2.9e-02
5 OFC gene expression LOC102550499 0.23 0.13 1.4e-04 0.16 0.14 0.12 0.15 1.2e-04 4.3e-04 7.5e-04 2.1e-04
6 NAcc gene expression LOC102550499 0.07 0.05 9.7e-08 0.07 0.07 0.07 0.07 4.4e-08 3.7e-08 1.2e-08 4.1e-08
7 Brain gene expression LOC102550499 0.16 0.09 4.4e-13 0.13 0.13 0.13 0.13 4.6e-12 3.4e-12 1.0e-11 5.7e-12
8 Adipose gene expression LOC102550499 0.04 0.04 8.3e-03 0.01 0.01 0.02 0.01 3.1e-02 2.9e-02 2.6e-03 3.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.20.30.90.40.20.4-0.70.60.2-0.61.0
Area under the delay curve0.50.53.4-0.2-0.2-0.10.3-0.00.5-0.21.8
BMI with tail0.10.30.70.70.40.6-0.40.50.3-0.3-0.8
BMI without tail0.30.51.3-0.5-0.7-0.50.7-0.6-0.70.7-1.2
Body weight2.29.413.5-3.5-3.7-3.42.9-3.0-3.43.00.3
Weight adjusted by age0.10.10.20.40.50.3-0.30.40.3-0.2-0.2
Bone surface0.20.30.5-0.6-0.6-0.60.1-0.3-0.70.20.7
Bone volume0.20.30.5-0.6-0.7-0.60.2-0.3-0.70.30.6
Breakpoint value in progressive ratio session1.51.63.9-1.3-1.1-1.22.0-1.2-0.31.4-1.0
Number of licking bursts2.02.33.81.61.81.6-2.01.41.2-1.70.3
Context. condit. distance diff. score0.10.10.10.30.40.2-0.20.20.4-0.20.1
Locomotion velocity, session 12.22.33.51.71.71.7-1.31.61.9-1.50.4
Locomotion distance, session 10.70.81.1-1.0-1.0-1.01.0-1.1-0.90.9-0.3
Locomotion velocity, session 20.30.30.50.70.30.6-0.60.70.4-0.50.4
Locomotion distance, session 20.30.40.70.80.70.8-0.40.70.7-0.3-0.3
Locomotion velocity, session 30.30.31.20.50.60.4-1.10.2-0.2-0.60.0
Locomotion distance, session 35.45.87.6-2.6-2.5-2.72.2-2.7-2.82.4-1.1
Stereotopy head waving bouts, day 30.50.61.80.80.90.7-0.50.50.5-0.2-1.4
Stereotopy head waving duration, day 32.12.63.81.91.91.8-1.61.71.6-1.4-0.2
Locomotion velocity, session 70.10.10.40.0-0.2-0.0-0.40.2-0.2-0.20.6
Locomotion distance, session 70.10.10.3-0.3-0.5-0.3-0.0-0.2-0.60.10.2
Stereotopy head waving bouts, day 70.10.10.40.30.30.2-0.00.20.10.1-0.6
Stereotopy head waving duration, day 70.70.81.31.11.11.0-0.71.01.0-0.6-0.3
Locomotion velocity, session 82.63.24.32.02.01.9-2.11.91.5-1.80.4
Locomotion distance, session 80.20.30.70.70.70.6-0.30.60.8-0.3-0.3
Degree of sensitization distance3.43.44.41.91.72.0-1.82.11.9-2.01.2
Degree of sensitization stereotypy0.10.10.60.10.2-0.00.3-0.00.10.4-0.8
Conditioned locomotion0.60.71.7-0.5-0.5-0.70.2-0.8-1.30.7-1.2
Cocaine response after cond. corrected0.40.51.1-0.6-0.7-0.70.4-0.8-1.00.6-0.6
Cocaine response after cond. not corrected0.90.92.1-0.8-1.0-0.90.6-1.0-1.40.9-0.9
Cocaine response before conditioning2.02.43.0-1.4-1.5-1.51.4-1.5-1.71.7-1.6
Saline control response0.60.81.8-0.7-0.6-0.71.2-0.7-0.41.1-1.3
Bone: connectivity density0.71.11.71.00.81.0-1.21.20.8-1.21.3
Bone: cortical apparent density1.72.23.01.71.71.7-1.21.71.7-1.30.0
Bone: cortical area2.02.93.7-1.8-1.8-1.81.9-1.6-1.61.9-1.2
Bone: cortical porosity0.40.50.80.90.70.8-0.80.70.4-0.5-0.4
Bone: cortical porosity0.50.50.91.00.80.8-0.90.70.4-0.5-0.4
Bone: cortical thickness0.91.51.9-1.2-1.1-1.31.3-1.1-1.11.4-1.1
Bone: cortical thickness0.10.10.20.30.10.2-0.40.2-0.2-0.1-0.4
Bone: cortical tissue density2.02.73.61.91.81.9-1.41.91.9-1.40.1
Condit. Reinf. active minus inactive responses0.20.30.40.50.60.5-0.60.50.4-0.6-0.2
Condit. Reinf. active-inactive response ratio0.20.20.60.50.80.4-0.40.40.6-0.3-0.5
Condit. Reinf. active responses0.91.11.61.11.01.1-1.31.20.8-1.10.3
Condit. Reinf. inactive responses0.50.61.00.90.50.9-0.91.00.5-0.90.6
Incentive salience index mean0.00.10.20.10.00.1-0.50.1-0.3-0.30.1
Condit. Reinf. lever presses0.20.20.5-0.4-0.7-0.40.1-0.4-0.70.20.4
Condit. Reinf. active minus inactive responses4.35.36.2-2.3-2.2-2.42.4-2.5-2.22.4-1.9
Condit. Reinf. active-inactive response ratio3.63.85.4-1.7-1.6-1.82.1-2.0-1.72.3-2.3
Condit. Reinf. active responses4.66.47.4-2.7-2.6-2.72.6-2.7-2.52.6-1.9
Condit. Reinf. inactive responses1.21.52.3-1.5-1.5-1.41.4-1.2-1.11.1-0.2
Condit. Reinf. lever presses5.98.010.7-3.3-3.2-3.12.8-3.1-2.92.6-1.1
Condit. Reinf. lever reinforcers received5.47.78.9-2.9-2.8-2.92.7-3.0-2.92.8-2.0
Conditioned reinforcement - actives0.60.61.6-0.5-0.6-0.60.2-0.7-1.10.5-1.3
Conditioned reinforcement - inactives1.71.92.7-1.5-1.5-1.51.1-1.6-1.61.20.1
Conditioned locomotion0.81.02.01.21.11.0-1.40.80.3-1.1-0.6
Patch foraging indifference point 0 sec0.30.51.1-0.7-0.9-0.60.5-0.7-1.00.6-0.7
Patch foraging indifference point AUC0.40.51.10.60.60.7-0.20.91.1-0.20.7
Delay disc. indifference point, 0s delay0.60.71.3-0.8-1.0-0.81.1-0.6-0.30.71.0
Delay disc. indifference point, 16s delay1.31.32.3-1.3-1.5-1.20.9-1.0-1.00.61.5
Delay disc. indifference point, 2s delay0.40.52.4-0.00.10.10.10.21.0-0.51.6
Delay disc. indifference point, 24s delay1.21.22.7-1.2-1.2-1.10.8-0.8-0.70.61.6
Delay disc. indifference point, 4s delay0.10.10.4-0.3-0.3-0.20.3-0.2-0.20.10.6
Delay disc. indifference point, 8s delay1.11.22.50.80.90.9-0.51.01.5-1.01.6
Indifference point function ln k0.40.51.4-0.8-0.8-0.80.2-0.9-1.20.3-0.4
Indifference point function log k0.40.51.4-0.8-0.8-0.80.2-0.9-1.20.3-0.4
Patch foraging total patch changes 0 sec0.40.61.1-0.8-0.9-0.70.6-0.8-1.00.6-0.6
Patch foraging total patch changes 12 sec0.30.40.8-0.7-0.9-0.60.8-0.5-0.60.80.1
Patch foraging total patch changes 18 sec0.10.20.70.30.20.40.30.60.80.20.1
Patch foraging total patch changes 24 sec0.50.61.1-1.0-1.1-0.80.9-0.6-0.60.80.4
Patch foraging total patch changes 6 sec0.10.20.4-0.4-0.6-0.30.6-0.1-0.30.6-0.3
Patch foraging time to switch 0 sec1.21.82.41.31.11.4-1.21.41.4-1.31.5
Patch foraging water rate 0 sec0.40.71.70.91.00.8-1.30.70.3-1.00.1
Patch foraging water rate 12 sec0.60.91.4-1.1-0.9-1.20.6-1.2-1.10.70.3
Patch foraging water rate 18 sec0.71.02.00.91.10.9-1.40.80.7-1.40.2
Patch foraging water rate 24 sec0.40.61.3-0.6-0.2-0.80.3-1.0-0.90.5-1.2
Patch foraging water rate 6 sec0.00.10.1-0.3-0.0-0.3-0.3-0.3-0.3-0.20.2
Seeking ratio, delayed vs. immediate footshock1.01.21.7-1.2-1.2-1.01.3-1.2-0.81.2-0.8
Distance traveled before self-admin2.02.12.7-1.5-1.3-1.41.4-1.6-1.51.5-1.4
Distance traveled after self-admin4.55.06.4-2.5-2.3-2.52.3-2.4-2.32.2-0.8
Extensor digitorum longus weight0.20.60.90.90.60.9-0.90.90.6-0.90.4
Bone: elastic displacement0.10.10.20.20.10.2-0.30.30.2-0.30.4
Bone: elastic work1.92.53.3-1.7-1.8-1.71.4-1.5-1.81.6-0.7
Bone: endosteal estimation1.02.23.2-1.7-1.8-1.61.8-1.4-1.21.5-0.3
Bone: endosteal perimeter0.81.72.5-1.5-1.6-1.51.5-1.3-1.11.20.0
Epididymis fat weight0.00.00.10.1-0.00.1-0.10.00.1-0.10.2
Delta time in closed arm before/after self-admin0.70.61.4-0.8-1.2-0.70.3-0.7-1.10.21.0
Delta time in open arm before/after self-admin0.30.32.00.30.60.3-0.10.10.30.1-1.4
Diff in mean of infusions in LGA sessions0.20.20.6-0.4-0.2-0.30.7-0.30.40.5-0.2
Delay discount exponential model param0.40.43.00.30.20.2-0.30.0-0.40.2-1.7
Extinction: sum of active levers before priming1.31.32.4-1.2-1.3-1.01.5-1.1-0.61.3-0.8
Active lever presses in extinction session 60.30.30.6-0.6-0.7-0.60.8-0.4-0.20.40.4
Bone: final force1.52.53.1-1.7-1.7-1.81.6-1.6-1.61.7-0.6
Bone: final moment2.33.74.5-2.1-2.1-2.11.9-1.9-2.02.0-0.9
Food consumed during 24 hour testing period0.20.30.5-0.7-0.6-0.60.2-0.7-0.70.20.2
Glucose0.60.92.40.70.40.7-1.20.80.2-1.11.6
Heart weight0.81.11.8-1.0-1.0-1.00.9-1.1-1.31.1-0.8
Delay discount hyperbolic model param0.40.42.90.10.10.1-0.2-0.1-0.60.3-1.7
Intermittent access intake day 1-15 change1.41.42.2-1.3-1.5-1.11.2-1.1-0.81.01.1
Intermittent access intake escalation0.90.91.5-1.0-1.2-0.91.0-1.0-0.70.80.6
Intermittent access intake escalation 23.23.15.0-1.9-2.1-1.72.2-1.8-1.32.0-0.3
Intermitt. access day 1 inactive lever presses0.40.41.2-0.7-0.8-0.5-0.0-0.5-0.7-0.21.1
Intermitt. access day 15 inactive lever presses0.30.31.4-0.5-0.6-0.4-0.3-0.3-0.5-0.31.2
Intermitt. access escalation Index1.00.96.3-0.20.0-0.30.5-0.6-0.20.5-2.5
Intermittent access day 1 total infusions0.91.17.10.30.50.0-0.6-0.4-0.9-0.1-2.7
Intermittent access day 15 total infusions1.01.22.0-0.9-0.8-1.00.7-1.4-1.20.9-1.4
Intermittent access terminal intake (last 3 days)1.61.72.7-1.2-1.2-1.31.1-1.6-1.51.3-1.2
Intermittent access total infusions1.01.13.9-0.7-0.5-0.80.3-1.2-1.30.7-2.0
Intermittent access day 1 locomotion1.21.38.90.20.2-0.1-0.5-0.3-1.1-0.0-3.0
Intermittent access day 15 total locomotion0.10.10.30.1-0.20.1-0.50.0-0.6-0.3-0.0
Intermittent access total locomotion0.40.41.10.70.40.5-1.00.4-0.3-0.8-0.7
Intermittent access standard deviation4.04.26.8-2.3-2.1-2.22.6-2.3-1.42.2-0.4
Left kidney weight2.67.310.4-2.9-2.9-2.82.4-2.6-3.22.9-1.5
Right kidney weight3.610.112.7-3.6-3.6-3.43.2-3.3-3.53.3-0.5
Cocaine induced anxiety0.10.10.9-0.10.00.00.20.00.3-0.01.0
Post-drug Anxiety0.60.62.20.50.50.6-0.50.80.7-0.71.5
Baseline Anxiety0.40.42.30.40.40.3-0.40.3-0.2-0.1-1.5
Tail length4.012.216.3-4.0-3.9-3.93.6-3.7-3.53.4-0.0
Length with tail6.022.130.3-5.5-5.4-5.34.6-4.9-4.94.50.7
Length without tail2.86.18.8-3.0-2.8-2.92.3-2.5-2.62.30.6
Times rat made contact with spout0.20.30.40.70.60.6-0.30.60.6-0.2-0.2
Lifetime Intake0.70.84.7-0.1-0.0-0.3-0.2-0.7-0.80.2-2.2
Liver weight, left0.00.10.20.2-0.20.3-0.20.3-0.40.0-0.4
Liver weight, right0.00.00.1-0.1-0.3-0.1-0.1-0.2-0.40.10.1
Locomotor activity0.40.60.90.80.60.9-0.51.00.8-0.50.9
Locomotor testing distance0.71.21.61.21.21.3-0.91.31.3-0.90.3
Locomotor testing rearing0.91.52.51.51.31.5-0.71.61.5-0.6-0.2
Locomotion in novel chamber0.30.30.70.60.50.7-0.20.70.9-0.50.3
Locomotion in novel chamber post-restriction0.00.10.3-0.00.30.00.1-0.00.5-0.1-0.2
Fecal boli incidents, locomotor time 13.13.45.51.91.61.9-2.22.01.2-2.31.3
Change in fecal boli incidents, locomotor task0.70.72.5-0.4-0.2-0.41.1-0.5-0.01.0-1.6
Time >=10cm from walls, locomotor time 10.00.00.10.10.10.1-0.20.3-0.2-0.2-0.3
Bouts of movement, locomotor time 10.20.20.6-0.6-0.5-0.40.8-0.1-0.10.2-0.1
Total resting periods, locomotor time 10.10.10.3-0.4-0.3-0.20.5-0.00.0-0.0-0.3
Rest time, locomotor task time 10.10.10.20.20.10.2-0.40.3-0.2-0.4-0.1
Distance moved, locomotor task time 10.20.20.5-0.3-0.2-0.40.5-0.6-0.20.7-0.2
Vertical activity count, locomotor time 11.21.31.8-1.1-0.9-1.21.3-1.2-0.91.3-1.1
Time >=10cm from walls, locomotor time 20.00.00.1-0.2-0.2-0.10.30.1-0.10.3-0.1
Bouts of movement, locomotor time 20.70.83.20.2-0.20.5-0.80.90.0-1.01.8
Total resting periods, locomotor time 20.60.62.10.2-0.10.5-0.80.9-0.0-1.01.5
Rest time, locomotor task time 20.40.51.9-0.4-0.2-0.50.4-0.7-0.70.5-1.4
Distance moved, locomotor task time 20.00.00.10.20.10.10.10.30.30.20.2
Vertical activity count, locomotor time 20.20.20.6-0.4-0.5-0.30.8-0.10.10.50.2
Light reinforcement 10.30.52.60.40.20.6-0.50.60.5-0.51.6
Light reinforcement 26.58.711.13.13.13.1-3.32.92.8-3.31.4
Bone: marrow area1.12.33.3-1.7-1.8-1.61.8-1.5-1.31.6-0.4
Bone: maximum diameter1.22.23.1-1.7-1.8-1.71.4-1.4-1.71.4-0.4
Bone: maximum force2.64.45.4-2.3-2.2-2.32.3-2.0-1.92.3-1.1
Bone: maximum moment3.45.87.0-2.7-2.6-2.72.6-2.3-2.32.6-1.4
Mean time between licks in bursts0.20.20.4-0.5-0.6-0.50.3-0.5-0.60.4-0.2
Mean num. licks in bursts0.91.12.3-1.0-1.2-1.01.5-0.8-0.71.4-0.4
Cd content in liver0.40.41.40.60.80.6-0.00.51.2-0.3-0.1
Co content in liver1.61.92.31.51.51.5-1.51.41.4-1.50.2
Cu content in liver1.01.22.3-1.3-1.2-1.20.7-1.3-1.50.90.0
Fe content in liver0.60.71.60.60.50.7-0.90.80.6-1.01.3
K content in liver0.70.71.5-0.8-1.0-0.80.5-0.9-1.20.8-0.3
Mg content in liver0.10.10.5-0.2-0.2-0.2-0.3-0.3-0.70.2-0.2
Mn content in liver1.11.23.7-0.6-0.7-0.80.8-0.9-1.21.3-1.9
Na content in liver5.15.47.0-2.5-2.6-2.52.3-2.4-2.62.4-1.0
Rb content in liver0.00.10.3-0.1-0.30.0-0.10.0-0.2-0.10.6
Se content in liver2.53.04.72.22.12.0-1.81.81.6-1.40.2
Sr content in liver0.70.61.00.91.00.8-0.90.60.7-0.7-0.6
Zn content in liver0.30.40.70.60.70.6-0.90.50.4-0.80.4
Bone: minimum diameter5.410.114.5-3.3-3.2-3.33.8-3.1-2.63.6-2.2
Time in familiar zone, hab. session 10.30.30.5-0.5-0.7-0.50.6-0.4-0.40.50.1
Time in novel zone, hab. session 10.10.10.30.40.50.4-0.40.20.2-0.2-0.4
Total zone transitions, hab. session 10.70.91.9-0.9-1.1-0.91.4-0.7-0.61.2-0.7
Total locomotion distance, hab. session 12.94.17.2-2.2-2.3-2.12.7-1.9-1.42.3-0.9
Locomotion velocity, hab. session 11.31.83.5-1.4-1.5-1.41.9-1.2-0.81.5-0.6
Time in familiar zone, hab. session 20.30.30.5-0.7-0.5-0.70.6-0.6-0.20.40.4
Time in novel zone, hab. session 20.40.40.70.80.70.8-0.70.80.5-0.6-0.0
Total zone transitions, hab. session 20.10.10.70.20.10.1-0.1-0.0-0.20.2-0.8
Total locomotion distance, hab. session 20.50.70.9-0.8-0.7-0.81.0-0.8-0.61.0-0.8
Locomotion velocity, hab. session 20.50.70.9-0.7-0.7-0.70.9-0.8-0.71.0-1.0
Novel to familiar place preference ratio1.21.22.3-1.1-1.1-1.11.5-1.0-0.71.4-0.7
Novelty place preference1.01.01.8-1.0-1.1-1.01.4-0.9-0.81.2-0.5
Time in novel zone, NPP test0.70.71.3-0.8-0.9-0.81.1-0.7-0.61.0-0.5
Total zone transitions, NPP test0.10.20.40.40.30.4-0.40.40.4-0.50.6
Total locomotion distance, NPP test1.52.03.5-1.6-1.5-1.51.9-1.4-0.91.5-0.5
Locomotion velocity, NPP test1.92.74.4-1.8-1.7-1.82.1-1.7-1.21.7-0.7
Intraocular pressure0.30.52.40.30.40.3-0.40.50.5-0.71.6
Delta distance traveled before/after self-admin0.40.50.9-0.8-0.8-0.80.8-0.4-0.40.41.0
Delta ambulatory time before/after self-admin0.91.01.4-1.1-1.1-1.21.2-0.9-0.81.0-0.1
Parametrial fat weight0.40.81.71.11.01.0-1.30.90.5-1.00.1
Pavlov. Cond. lever latency0.20.30.60.40.60.4-0.30.50.8-0.50.3
Pavlov. Cond. magazine entry latency0.10.10.30.40.40.4-0.50.30.2-0.50.1
Pavlov. Cond. change in total contacts0.00.00.0-0.0-0.0-0.0-0.10.0-0.1-0.00.1
Pavlov. Cond. index score0.00.10.2-0.1-0.2-0.1-0.1-0.2-0.50.2-0.2
Pavlov. Cond. latency score0.10.10.4-0.2-0.4-0.20.1-0.3-0.60.3-0.2
Pavlov. Cond. lever contacts0.80.91.7-1.0-1.3-1.00.7-0.9-1.30.9-0.2
Pavlov. Cond. magazine entry number0.00.00.1-0.2-0.2-0.20.3-0.1-0.00.20.2
Pavlov. Cond. intertrial magazine entries0.10.10.20.40.40.4-0.10.30.4-0.0-0.4
Pavlov. Cond. lever-magazine prob. diff.0.10.20.6-0.2-0.4-0.30.1-0.4-0.80.4-0.4
Pavlov. Cond. response bias0.10.10.4-0.3-0.5-0.30.2-0.4-0.60.3-0.2
Pavlov. Cond. lever latency2.63.54.82.22.12.1-1.92.01.8-1.70.7
Pavlov. Cond. magazine entry latency1.31.52.4-1.5-1.6-1.40.8-1.3-1.50.80.4
Pavlov. Cond. change in total contacts5.37.39.5-3.1-2.9-3.02.9-2.9-2.52.6-1.2
Pavlov. Cond. index score2.22.94.3-2.1-2.1-1.91.6-1.8-1.71.4-0.1
Pavlov. Cond. latency score2.12.63.9-2.0-2.0-1.81.5-1.8-1.71.3-0.1
Pavlov. Cond. lever contacts2.53.44.7-2.2-2.1-2.11.9-2.0-1.81.7-0.7
Pavlov. Cond. magazine entry number0.81.01.71.31.31.1-0.71.00.9-0.4-0.8
Pavlov. Cond. intertrial magazine entries0.70.91.61.11.21.0-1.30.90.6-0.90.1
Pavlov. Cond. lever-magazine prob. diff.2.63.35.0-2.2-2.2-2.11.7-1.9-1.91.5-0.2
Pavlov. Cond. response bias2.83.85.3-2.3-2.2-2.22.0-2.1-1.91.8-0.6
Time in closed arm before self-admin0.20.31.60.30.70.2-0.1-0.00.20.0-1.3
Time in closed arm after self-admin0.20.20.8-0.5-0.7-0.40.0-0.6-0.9-0.0-0.2
Time in open arm before self-admin1.11.22.0-1.2-1.4-1.21.0-0.9-1.21.00.6
Time in open arm after self-admin1.01.11.9-0.9-0.8-0.91.2-0.7-0.81.4-1.3
Bone: periosteal estimation1.83.85.2-2.1-2.2-2.12.3-1.8-1.72.2-1.0
Bone: periosteal perimeter1.52.63.5-1.8-1.8-1.71.9-1.5-1.41.7-0.7
Bone: post-yield work0.60.81.4-1.0-1.0-1.01.2-1.0-0.50.8-0.4
Progressive ratio test 1 active lever presses3.13.211.8-1.2-1.1-1.30.8-1.8-2.01.2-3.4
Progressive ratio test 1 breakpoint3.13.28.7-1.4-1.3-1.41.0-1.9-2.21.4-2.9
Progressive ratio test 1 inactive lever presses0.30.41.0-0.5-0.5-0.50.1-0.6-0.80.0-1.0
Progressive ratio test 2 active lever presses0.80.91.9-0.8-0.8-0.80.3-1.1-1.30.4-1.4
Progressive ratio test 2 breakpoint0.80.92.0-0.8-0.8-0.80.2-1.1-1.40.4-1.4
Progressive ratio test 2 inactive lever presses2.12.43.4-1.8-1.7-1.71.3-1.8-1.71.1-0.7
Incentive Sensitization - Responses0.20.21.2-0.1-0.20.1-0.30.1-0.1-0.41.1
Incentive Sensitization - Breakpoint0.30.32.00.1-0.10.3-0.50.40.1-0.61.4
Sum of active levers in priming session hrs 5-60.30.31.1-0.2-0.1-0.11.0-0.10.50.8-0.5
Progressive ratio0.50.61.40.70.50.6-0.40.61.2-0.71.0
Food seeking constrained by brief footshock2.93.54.8-2.0-1.8-2.02.2-2.0-1.52.0-1.6
Seeking ratio, punishment vs. effort1.92.33.2-1.5-1.2-1.51.3-1.6-1.81.5-1.8
Retroperitoneal fat weight0.82.83.71.81.51.9-1.91.91.2-1.61.3
Reaction time number correct0.20.31.6-0.1-0.2-0.20.1-0.4-0.60.5-1.3
Reaction time mean minus median0.20.20.6-0.5-0.5-0.50.3-0.5-0.80.40.3
Reaction time mean minus median AUC0.30.41.3-0.7-0.7-0.60.2-0.6-1.10.40.1
Reaction time num false alarms0.71.01.31.21.01.1-1.01.10.8-0.9-0.7
Reaction time num false alarms AUC1.01.31.81.41.31.3-1.21.31.0-1.1-0.6
Reaction time trials correct on left0.20.31.6-0.1-0.2-0.20.1-0.4-0.60.5-1.3
Reaction time trials on left0.20.31.6-0.1-0.1-0.20.1-0.4-0.60.5-1.3
Reaction time mean0.10.10.30.30.30.2-0.60.0-0.1-0.50.4
Reaction time mean AUC0.20.20.80.50.40.4-0.90.2-0.1-0.70.3
Median of all reaction times0.20.20.60.60.50.4-0.70.20.2-0.70.2
Reaction time omissions0.20.20.50.60.60.4-0.50.3-0.0-0.3-0.7
Reaction time false alarm rate1.01.41.91.31.21.3-1.21.41.2-1.40.3
Reaction time premature initiation rate0.00.00.1-0.1-0.0-0.00.20.10.2-0.00.0
Reaction time premature initiations0.00.10.4-0.1-0.1-0.10.2-0.1-0.10.3-0.6
Std. dev. reaction times0.10.10.5-0.3-0.2-0.40.0-0.5-0.70.20.3
Reaction time trials completed0.20.31.6-0.1-0.1-0.20.1-0.4-0.60.5-1.3
Reaction time trials AUC0.20.32.00.00.0-0.1-0.0-0.3-0.60.4-1.4
Run reversals in cocaine runway, females0.60.61.30.50.50.5-1.10.70.2-1.10.8
Run reversals in cocaine runway, males0.80.81.61.01.21.0-0.90.80.9-0.6-0.5
Latency to leave start box in cocaine runway0.30.42.30.20.10.2-0.20.40.4-0.21.5
Latency to leave start box in cocaine runway, F0.60.61.70.60.60.7-0.50.80.9-0.51.3
Latency to leave start box in cocaine runway, M0.00.00.0-0.2-0.2-0.20.0-0.1-0.1-0.00.2
Std. dev. time between licks in bursts0.60.71.1-0.9-1.1-0.91.0-0.8-0.60.90.1
Total sessions with >9 infusions1.11.39.10.30.20.0-0.2-0.4-0.70.3-3.0
Short access day 1 total inactive lever presses0.30.30.6-0.7-0.7-0.60.3-0.7-0.70.20.2
Short access day 10 total inactive lever presses0.20.20.8-0.5-0.6-0.50.1-0.4-0.4-0.10.9
Short access day 1 total infusions0.91.05.1-0.5-0.4-0.50.3-0.8-1.00.7-2.3
Short access day 10 total infusions0.60.64.10.40.60.2-0.5-0.1-0.2-0.2-2.0
Short access total infusions0.80.95.90.40.50.3-0.6-0.0-0.4-0.2-2.4
Short access day 1 locomotion0.91.01.51.21.01.2-1.21.10.6-0.9-0.7
Short access day 10 total locomotion0.70.82.2-0.6-0.8-0.80.4-0.7-1.20.5-1.5
Short access total locomotion0.70.74.70.40.10.2-0.50.1-0.7-0.2-2.2
One hour access (0.3 mA shock)1.31.52.5-1.3-1.4-1.41.1-1.6-1.31.0-0.8
Compulsive drug intake0.30.30.8-0.5-0.4-0.60.9-0.4-0.10.7-0.5
One hour access (shock baseline)0.20.30.7-0.4-0.6-0.50.1-0.8-0.80.2-0.3
Social response proportion4.64.96.4-2.2-2.0-2.42.1-2.5-2.52.3-1.5
Social responses0.10.20.6-0.3-0.4-0.30.0-0.2-0.60.00.8
Social time0.40.51.2-0.8-0.6-0.61.0-0.5-0.10.51.1
Soleus weight0.72.13.81.51.41.6-1.01.62.0-1.41.0
Bone: stiffness1.32.13.0-1.5-1.4-1.61.7-1.4-1.11.6-1.0
Tibialis anterior weight0.00.10.3-0.0-0.2-0.00.50.0-0.00.4-0.5
Time to tail flick, vehicle, before self-admin0.30.31.3-0.3-0.7-0.4-0.1-0.4-1.20.4-0.6
Time to tail flick, vehicle, after self-admin0.10.20.6-0.4-0.2-0.40.1-0.4-0.40.0-0.8
Time to tail flick, test, before self-admin0.10.10.4-0.2-0.5-0.30.10.1-0.60.4-0.1
Time to tail flick, test, after self-admin0.10.10.6-0.1-0.3-0.2-0.1-0.2-0.80.2-0.6
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.20.1-0.20.3-0.30.00.1-0.5
Delta time to tail flick, test, before/after SA0.00.00.10.10.20.0-0.2-0.2-0.1-0.0-0.3
Tibia length1.85.07.0-2.5-2.6-2.42.0-2.3-2.62.2-0.9
Ambulatory time before self-admin1.11.11.5-1.1-0.9-1.01.1-1.2-1.11.1-0.9
Ambulatory time after self-admin4.55.06.6-2.6-2.2-2.52.4-2.5-2.12.2-0.6
Bone: tissue strength3.83.74.6-2.1-1.9-2.22.0-2.1-1.82.0-1.1
Total heroin consumption1.82.15.1-1.4-1.3-1.32.3-1.3-0.51.9-1.1
Bone: trabecular number0.10.20.4-0.3-0.6-0.30.1-0.2-0.50.10.6
Bone: trabecular spacing1.82.33.1-1.5-1.4-1.61.8-1.6-1.21.7-1.2
Bone: trabecular thickness0.30.30.90.50.30.5-0.90.6-0.1-0.60.4
Bone: trabecular tissue density2.33.24.02.01.92.0-1.72.01.9-1.70.8
Water consumed over 24 hours0.81.01.8-0.9-1.0-1.00.7-1.1-1.31.0-0.5
Number of responses in last shaping day2.12.23.3-1.5-1.4-1.51.4-1.8-1.51.6-0.9