Hub : Genes

LOC102549885

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC102549885 0.08 0.04 1.0e-08 0.1 0.1 0.09 0.09 3.8e-08 4.7e-08 1.1e-07 8.1e-08
2 Brain gene expression LOC102549885 0.24 0.14 0.0e+00 0.25 0.25 0.25 0.26 1.2e-23 3.9e-23 3.5e-23 5.7e-24
3 PL gene expression LOC102549885 0.37 0.13 0.0e+00 0.3 0.3 0.31 0.31 1.2e-33 1.0e-33 1.6e-34 2.1e-34
4 OFC gene expression LOC102549885 0.3 0.16 7.3e-04 0.02 0.07 0.01 0.04 1.1e-01 9.4e-03 2.2e-01 5.2e-02
5 BLA gene expression LOC102549885 0.1 0.07 4.3e-06 0.08 0.08 0.06 0.05 3.9e-05 5.2e-05 5.3e-04 1.7e-03
6 LHb gene expression LOC102549885 0.18 0.12 1.1e-03 0.05 0.08 0.03 0.02 2.9e-02 5.4e-03 6.7e-02 9.2e-02
7 NAcc gene expression LOC102549885 0.16 0.08 0.0e+00 0.22 0.23 0.23 0.23 1.6e-32 6.3e-35 8.2e-34 3.0e-34
8 IC gene expression LOC102549885 0.17 0.09 2.6e-08 0.14 0.18 0.19 0.17 1.2e-06 5.6e-08 2.5e-08 1.2e-07
9 IL gene expression LOC102549885 0.39 0.18 9.7e-05 0.1 0.14 0.15 0.14 2.0e-03 3.1e-04 2.1e-04 3.8e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.30.60.90.70.90.70.80.70.60.60.91.0
Area under the delay curve1.71.92.61.51.41.41.51.41.41.20.91.6
BMI with tail1.65.47.0-2.7-2.5-2.5-2.3-2.5-2.5-2.4-0.9-2.3
BMI without tail0.51.52.7-1.1-1.6-1.1-1.2-1.3-1.0-1.0-0.8-1.6
Body weight1.35.69.5-2.4-3.1-2.3-1.9-2.7-2.3-2.3-2.1-2.0
Weight adjusted by age0.10.20.3-0.4-0.3-0.4-0.5-0.5-0.4-0.2-0.4-0.5
Bone surface0.10.10.30.30.30.30.40.50.20.20.50.3
Bone volume0.10.10.20.20.30.30.30.40.20.20.40.3
Breakpoint value in progressive ratio session0.10.10.5-0.0-0.70.00.1-0.2-0.1-0.1-0.10.0
Number of licking bursts0.20.30.70.40.30.40.00.70.70.70.9-0.2
Context. condit. distance diff. score5.16.28.6-2.7-2.5-2.9-2.9-2.3-2.7-2.6-1.3-1.9
Locomotion velocity, session 10.80.81.5-1.1-0.6-0.9-0.6-1.1-1.2-1.1-0.8-0.3
Locomotion distance, session 10.20.20.80.10.90.20.40.20.10.20.20.9
Locomotion velocity, session 21.31.53.1-1.4-0.8-1.1-1.3-1.8-1.2-0.9-0.4-1.5
Locomotion distance, session 20.81.13.00.71.51.01.40.50.60.70.21.7
Locomotion velocity, session 30.91.01.7-1.1-0.5-1.1-1.3-1.1-1.1-0.80.2-1.2
Locomotion distance, session 30.80.92.80.71.30.70.20.80.81.11.7-0.1
Stereotopy head waving bouts, day 31.11.34.7-0.8-0.9-0.7-0.3-1.5-1.1-1.1-2.2-0.3
Stereotopy head waving duration, day 35.05.910.8-2.4-2.5-2.2-2.0-2.7-2.4-2.3-3.3-1.7
Locomotion velocity, session 70.10.10.4-0.40.0-0.3-0.5-0.5-0.2-0.1-0.1-0.6
Locomotion distance, session 70.91.14.00.81.20.80.80.70.70.82.00.8
Stereotopy head waving bouts, day 74.14.65.9-2.3-1.9-2.1-2.4-2.4-2.1-1.8-2.0-2.2
Stereotopy head waving duration, day 73.44.15.7-2.1-1.9-1.9-2.4-2.0-1.7-1.5-2.2-2.3
Locomotion velocity, session 86.78.011.4-3.3-2.5-3.1-2.7-3.4-3.3-3.1-1.7-1.7
Locomotion distance, session 81.31.92.9-1.7-1.0-1.6-1.5-1.6-1.6-1.4-0.7-0.7
Degree of sensitization distance0.80.81.6-0.7-1.1-0.8-0.2-1.0-1.1-1.3-1.00.2
Degree of sensitization stereotypy3.74.06.4-2.2-1.8-2.1-2.5-2.1-1.9-1.6-1.3-2.2
Conditioned locomotion0.10.10.6-0.1-0.3-0.1-0.30.20.20.1-0.8-0.4
Cocaine response after cond. corrected0.10.10.5-0.30.0-0.3-0.70.0-0.10.1-0.3-0.7
Cocaine response after cond. not corrected0.30.31.5-0.40.1-0.3-1.00.1-0.00.2-0.2-1.2
Cocaine response before conditioning0.10.10.10.30.30.30.10.40.40.40.3-0.3
Saline control response0.30.31.0-0.4-0.8-0.4-0.7-0.4-0.2-0.1-0.6-1.0
Bone: connectivity density0.10.20.80.40.40.40.40.40.30.30.90.4
Bone: cortical apparent density1.82.43.81.81.61.72.01.41.51.40.61.7
Bone: cortical area1.21.93.0-1.4-1.5-1.3-1.5-0.8-1.1-1.1-1.7-1.5
Bone: cortical porosity0.40.52.2-0.3-0.2-0.4-0.7-0.2-0.2-0.21.5-1.1
Bone: cortical porosity0.91.02.5-1.0-1.0-1.0-1.3-0.8-0.8-0.80.4-1.6
Bone: cortical thickness0.10.20.60.2-0.40.30.60.50.2-0.0-0.80.3
Bone: cortical thickness0.30.41.1-0.5-0.8-0.5-0.2-0.3-0.6-0.8-1.00.3
Bone: cortical tissue density1.62.13.51.61.51.61.91.31.31.20.51.7
Condit. Reinf. active minus inactive responses1.71.92.71.51.31.51.51.61.41.30.71.4
Condit. Reinf. active-inactive response ratio0.10.10.40.2-0.10.10.00.60.30.20.1-0.0
Condit. Reinf. active responses3.34.05.22.12.32.22.12.22.12.10.91.7
Condit. Reinf. inactive responses2.73.35.01.82.22.02.01.61.81.91.11.6
Incentive salience index mean2.63.23.91.91.81.92.02.01.81.71.11.6
Condit. Reinf. lever presses2.33.24.32.01.92.02.11.71.71.71.11.6
Condit. Reinf. active minus inactive responses0.20.20.70.2-0.10.10.70.0-0.2-0.4-0.80.8
Condit. Reinf. active-inactive response ratio0.20.21.30.1-0.20.00.40.1-0.1-0.2-1.10.6
Condit. Reinf. active responses0.50.71.5-0.6-0.8-0.7-0.1-1.0-1.0-1.2-1.20.1
Condit. Reinf. inactive responses0.70.91.7-0.9-0.9-1.0-0.5-1.2-1.2-1.3-0.6-0.3
Condit. Reinf. lever presses0.20.20.70.40.70.50.8-0.00.10.1-0.50.6
Condit. Reinf. lever reinforcers received0.20.20.7-0.1-0.3-0.10.5-0.4-0.5-0.7-0.90.5
Conditioned reinforcement - actives0.10.10.50.10.40.30.4-0.20.10.10.40.7
Conditioned reinforcement - inactives0.30.41.4-0.6-0.3-0.4-0.0-0.8-0.6-0.6-1.20.7
Conditioned locomotion0.40.61.3-0.8-0.5-0.6-0.8-1.1-0.7-0.5-1.0-0.6
Patch foraging indifference point 0 sec0.10.20.70.40.20.40.50.20.40.40.90.6
Patch foraging indifference point AUC0.30.40.90.70.90.60.90.60.40.30.20.8
Delay disc. indifference point, 0s delay0.30.30.8-0.6-0.5-0.6-0.8-0.6-0.4-0.4-0.2-0.9
Delay disc. indifference point, 16s delay3.23.54.82.01.91.92.11.91.81.71.22.2
Delay disc. indifference point, 2s delay0.40.40.60.60.80.70.80.60.70.6-0.00.8
Delay disc. indifference point, 24s delay0.80.91.71.20.80.91.10.90.80.70.61.3
Delay disc. indifference point, 4s delay0.20.21.30.00.50.20.50.10.0-0.0-0.11.1
Delay disc. indifference point, 8s delay2.52.93.82.01.71.71.71.81.71.61.41.6
Indifference point function ln k0.81.32.8-1.0-1.7-1.1-1.4-1.2-1.0-0.9-0.1-1.4
Indifference point function log k0.81.32.8-1.0-1.7-1.1-1.4-1.2-1.0-0.9-0.1-1.4
Patch foraging total patch changes 0 sec0.20.31.20.50.30.50.50.40.50.51.10.5
Patch foraging total patch changes 12 sec0.10.10.2-0.2-0.1-0.30.0-0.2-0.4-0.50.20.2
Patch foraging total patch changes 18 sec0.20.41.20.60.00.50.70.40.50.31.10.6
Patch foraging total patch changes 24 sec0.10.10.40.30.60.40.10.00.30.50.4-0.4
Patch foraging total patch changes 6 sec0.20.31.60.10.00.00.30.30.0-0.11.30.7
Patch foraging time to switch 0 sec0.30.62.20.60.90.70.50.40.60.81.50.5
Patch foraging water rate 0 sec0.71.53.5-1.2-1.1-1.2-1.3-1.0-1.1-1.1-1.9-1.2
Patch foraging water rate 12 sec0.81.74.7-1.1-0.9-1.0-1.7-1.3-0.6-0.4-1.6-2.2
Patch foraging water rate 18 sec0.20.32.7-0.30.10.00.0-0.00.00.1-1.60.2
Patch foraging water rate 24 sec1.72.45.3-1.4-2.0-1.3-1.3-1.3-1.3-1.3-2.3-1.5
Patch foraging water rate 6 sec0.10.20.40.40.30.40.20.40.60.6-0.4-0.2
Seeking ratio, delayed vs. immediate footshock1.92.34.41.41.71.61.21.11.81.82.10.1
Distance traveled before self-admin0.40.50.90.80.60.60.71.00.50.40.90.4
Distance traveled after self-admin0.00.00.10.2-0.30.20.3-0.1-0.0-0.10.3-0.1
Extensor digitorum longus weight0.10.41.4-0.5-0.2-0.5-0.7-0.8-0.3-0.1-0.2-1.2
Bone: elastic displacement1.41.72.5-1.4-1.2-1.4-1.6-1.4-1.3-1.1-0.4-1.5
Bone: elastic work4.96.37.6-2.7-2.4-2.6-2.6-2.8-2.6-2.3-2.4-2.3
Bone: endosteal estimation2.45.49.3-2.7-1.5-2.6-3.1-2.4-2.5-2.0-0.9-2.5
Bone: endosteal perimeter2.04.38.6-2.2-1.6-2.2-2.9-1.8-1.8-1.3-1.2-2.9
Epididymis fat weight0.61.93.5-1.4-1.9-1.3-1.0-1.5-1.3-1.4-1.2-1.2
Delta time in closed arm before/after self-admin0.60.52.20.60.70.51.00.40.20.00.51.5
Delta time in open arm before/after self-admin1.81.85.2-1.4-0.6-1.2-1.8-1.3-0.9-0.6-1.0-2.3
Diff in mean of infusions in LGA sessions0.20.31.4-0.0-0.10.00.70.1-0.3-0.40.51.2
Delay discount exponential model param1.71.92.9-1.5-1.4-1.4-1.6-1.4-1.3-1.1-0.9-1.7
Extinction: sum of active levers before priming0.10.10.3-0.3-0.2-0.4-0.1-0.2-0.5-0.5-0.20.4
Active lever presses in extinction session 60.70.72.7-0.9-0.9-0.7-0.5-0.3-0.7-0.8-1.60.1
Bone: final force0.81.32.9-1.4-1.0-1.2-0.8-0.9-1.3-1.3-1.7-0.1
Bone: final moment1.32.13.9-1.7-1.3-1.5-1.1-1.2-1.6-1.6-2.0-0.3
Food consumed during 24 hour testing period2.43.35.2-1.8-2.0-1.9-1.4-1.7-2.0-2.1-2.3-0.4
Glucose0.40.61.11.00.60.80.91.10.90.7-0.20.6
Heart weight7.711.817.0-3.6-4.1-3.7-3.4-3.1-3.5-3.6-3.2-2.6
Delay discount hyperbolic model param1.31.52.4-1.3-1.2-1.2-1.4-1.2-1.1-1.0-0.7-1.5
Intermittent access intake day 1-15 change0.40.81.60.90.81.10.70.71.21.30.3-0.1
Intermittent access intake escalation0.50.91.91.01.01.20.80.81.31.40.3-0.0
Intermittent access intake escalation 21.01.11.80.91.21.31.11.11.31.40.40.5
Intermitt. access day 1 inactive lever presses0.10.30.7-0.4-0.6-0.6-0.2-0.4-0.8-0.80.10.1
Intermitt. access day 15 inactive lever presses0.20.41.5-0.2-0.0-0.20.4-0.3-0.5-0.6-1.21.1
Intermitt. access escalation Index0.30.40.60.60.50.80.60.40.70.7-0.70.5
Intermittent access day 1 total infusions0.40.71.2-0.9-0.6-0.9-0.8-1.1-1.0-0.9-0.50.0
Intermittent access day 15 total infusions0.10.10.30.10.50.40.0-0.10.40.6-0.30.0
Intermittent access terminal intake (last 3 days)0.10.20.7-0.00.80.30.1-0.40.20.4-0.70.3
Intermittent access total infusions0.20.30.7-0.60.1-0.4-0.7-0.9-0.4-0.2-0.7-0.2
Intermittent access day 1 locomotion0.00.00.10.10.10.1-0.1-0.20.10.2-0.00.2
Intermittent access day 15 total locomotion0.20.31.0-0.6-0.2-0.4-0.7-1.0-0.3-0.1-0.7-0.6
Intermittent access total locomotion0.40.51.1-0.7-0.1-0.5-0.9-1.1-0.5-0.2-0.9-0.9
Intermittent access standard deviation0.10.10.8-0.40.1-0.1-0.2-0.6-0.2-0.1-0.90.1
Left kidney weight12.859.772.1-8.1-8.4-7.9-7.2-8.5-8.2-7.9-6.9-6.0
Right kidney weight14.767.082.7-8.6-8.7-8.3-7.2-9.1-8.8-8.5-8.4-5.5
Cocaine induced anxiety1.21.72.4-1.2-1.5-1.4-1.1-0.9-1.4-1.5-1.5-0.9
Post-drug Anxiety0.20.21.1-0.0-0.7-0.3-0.10.4-0.3-0.4-1.00.3
Baseline Anxiety2.32.73.21.71.41.81.61.81.81.71.51.5
Tail length0.10.51.00.90.10.90.70.51.00.9-0.60.3
Length with tail0.31.34.8-0.9-1.4-0.8-0.7-1.2-0.8-0.8-2.2-0.6
Length without tail0.93.06.7-1.7-1.8-1.5-0.7-2.0-1.9-2.0-2.6-0.1
Times rat made contact with spout1.51.83.2-1.3-1.8-1.5-1.1-1.1-1.5-1.6-1.1-0.7
Lifetime Intake0.50.61.4-0.9-0.3-0.7-0.9-1.2-0.7-0.5-1.2-0.4
Liver weight, left0.30.54.1-0.1-0.70.00.2-0.5-0.1-0.1-2.0-0.1
Liver weight, right0.20.41.4-0.6-1.2-0.6-0.6-0.3-0.5-0.6-0.6-0.5
Locomotor activity2.23.54.5-2.0-1.9-2.0-2.0-2.1-1.8-1.7-1.6-1.6
Locomotor testing distance0.10.10.40.10.60.1-0.00.00.30.4-0.50.4
Locomotor testing rearing0.30.71.7-0.8-0.5-0.8-1.0-0.8-0.6-0.5-1.3-0.7
Locomotion in novel chamber0.50.61.60.70.50.7-0.10.31.01.30.6-1.0
Locomotion in novel chamber post-restriction0.71.11.71.01.31.00.61.31.21.21.1-0.0
Fecal boli incidents, locomotor time 10.00.10.20.40.40.00.2-0.1-0.1-0.1-0.30.2
Change in fecal boli incidents, locomotor task0.70.71.6-0.6-1.2-0.8-1.2-0.2-0.5-0.5-0.4-1.3
Time >=10cm from walls, locomotor time 10.10.10.4-0.40.2-0.3-0.3-0.4-0.4-0.20.7-0.1
Bouts of movement, locomotor time 10.20.20.90.20.30.40.5-0.00.20.1-1.00.7
Total resting periods, locomotor time 10.30.41.00.40.50.60.80.10.30.2-1.01.0
Rest time, locomotor task time 10.10.10.6-0.3-0.1-0.1-0.0-0.6-0.3-0.3-0.8-0.1
Distance moved, locomotor task time 10.10.21.7-0.3-0.3-0.2-0.1-0.0-0.2-0.21.30.0
Vertical activity count, locomotor time 10.10.21.6-0.1-0.1-0.1-0.00.3-0.1-0.11.30.4
Time >=10cm from walls, locomotor time 20.30.51.20.60.80.70.40.50.70.81.10.1
Bouts of movement, locomotor time 20.40.61.50.60.60.80.81.00.70.61.20.6
Total resting periods, locomotor time 20.30.60.90.60.50.80.90.90.70.50.90.7
Rest time, locomotor task time 20.10.20.30.40.20.50.60.40.50.40.20.3
Distance moved, locomotor task time 20.70.81.2-1.1-0.7-0.9-1.1-0.8-0.9-0.70.8-1.1
Vertical activity count, locomotor time 20.30.50.8-0.6-0.6-0.8-0.9-0.6-0.7-0.60.3-0.8
Light reinforcement 10.30.71.3-0.8-0.6-0.8-1.1-1.1-0.8-0.5-0.1-1.2
Light reinforcement 20.50.71.6-0.6-1.0-0.6-1.0-1.2-0.6-0.4-0.4-1.3
Bone: marrow area2.75.89.9-2.8-1.6-2.7-3.1-2.5-2.6-2.1-0.9-2.5
Bone: maximum diameter4.99.112.1-3.3-3.1-3.2-3.5-2.7-3.0-2.7-2.6-3.1
Bone: maximum force1.83.14.6-2.1-1.7-1.9-1.7-1.6-2.0-1.9-1.9-0.9
Bone: maximum moment2.54.36.0-2.5-2.0-2.3-1.9-1.9-2.3-2.3-2.2-1.1
Mean time between licks in bursts0.41.02.01.01.21.00.51.41.41.30.3-0.0
Mean num. licks in bursts1.52.43.9-1.5-1.6-1.6-0.9-1.7-1.9-2.0-1.6-0.3
Cd content in liver1.01.11.6-1.1-1.2-1.2-1.3-1.0-1.0-1.0-0.5-1.0
Co content in liver0.40.51.8-0.6-0.7-0.4-0.4-0.8-0.5-0.4-1.3-0.6
Cu content in liver6.67.910.43.02.93.22.72.53.23.22.61.5
Fe content in liver1.62.02.6-1.6-1.4-1.5-1.5-1.3-1.5-1.5-1.3-1.0
K content in liver1.61.53.51.21.21.51.90.20.91.00.51.7
Mg content in liver1.91.93.91.41.51.62.00.71.11.20.71.7
Mn content in liver0.10.10.70.10.10.30.4-0.50.00.2-0.8-0.2
Na content in liver1.31.41.91.11.21.31.21.31.41.30.51.0
Rb content in liver0.10.10.2-0.3-0.3-0.3-0.2-0.2-0.3-0.40.30.1
Se content in liver0.81.01.50.91.11.21.20.61.01.10.80.8
Sr content in liver1.81.52.41.61.31.41.51.01.31.20.51.0
Zn content in liver0.10.10.30.0-0.10.20.3-0.6-0.1-0.0-0.4-0.0
Bone: minimum diameter0.61.23.9-1.0-0.8-0.9-1.5-0.7-0.6-0.3-1.0-2.0
Time in familiar zone, hab. session 10.40.41.0-0.7-0.4-0.6-0.6-0.7-0.7-0.6-1.0-0.3
Time in novel zone, hab. session 10.60.61.9-0.7-0.9-0.8-1.1-0.3-0.4-0.50.0-1.4
Total zone transitions, hab. session 11.72.43.11.71.61.71.81.71.61.51.01.4
Total locomotion distance, hab. session 10.30.40.80.90.70.90.70.30.70.80.20.2
Locomotion velocity, hab. session 10.50.71.11.00.91.01.00.40.80.90.50.5
Time in familiar zone, hab. session 20.10.10.20.40.20.40.30.30.40.5-0.0-0.0
Time in novel zone, hab. session 20.60.60.8-0.9-0.9-0.9-0.9-0.6-0.8-0.9-0.2-0.6
Total zone transitions, hab. session 20.10.20.9-0.00.40.10.6-0.4-0.4-0.30.10.9
Total locomotion distance, hab. session 20.10.10.20.30.40.40.5-0.10.10.2-0.20.4
Locomotion velocity, hab. session 20.20.30.70.60.70.70.90.10.30.4-0.00.8
Novel to familiar place preference ratio2.32.54.1-1.6-2.0-1.5-1.7-1.2-1.3-1.3-1.9-1.6
Novelty place preference3.03.25.1-1.9-2.3-1.8-2.0-1.4-1.5-1.6-1.8-1.8
Time in novel zone, NPP test4.24.56.7-2.2-2.6-2.2-2.4-1.7-1.8-1.8-1.9-2.2
Total zone transitions, NPP test0.40.51.60.51.10.70.90.40.40.4-0.01.3
Total locomotion distance, NPP test0.10.10.40.40.70.40.3-0.20.20.4-0.10.3
Locomotion velocity, NPP test0.71.02.01.11.41.21.10.50.91.10.30.9
Intraocular pressure0.30.41.1-0.6-0.7-0.8-1.0-0.2-0.5-0.50.3-0.8
Delta distance traveled before/after self-admin1.41.52.3-1.4-1.5-1.2-1.2-1.4-1.2-1.1-0.7-1.3
Delta ambulatory time before/after self-admin1.62.03.9-1.5-2.0-1.4-1.4-1.3-1.3-1.3-0.6-1.4
Parametrial fat weight0.71.62.31.50.71.41.21.31.51.41.20.6
Pavlov. Cond. lever latency2.12.63.6-1.9-1.7-1.8-1.8-1.4-1.7-1.6-1.3-1.3
Pavlov. Cond. magazine entry latency2.83.65.22.01.71.92.12.01.91.62.31.7
Pavlov. Cond. change in total contacts3.33.54.42.01.62.02.12.01.81.61.91.7
Pavlov. Cond. index score2.53.24.01.91.61.82.01.81.71.52.01.6
Pavlov. Cond. latency score1.92.53.11.71.51.71.81.61.61.41.51.3
Pavlov. Cond. lever contacts4.25.06.42.52.32.52.42.12.32.21.91.8
Pavlov. Cond. magazine entry number3.44.36.0-2.2-1.8-2.1-2.2-2.2-2.0-1.8-2.4-1.8
Pavlov. Cond. intertrial magazine entries0.30.30.70.50.80.60.70.40.50.5-0.10.7
Pavlov. Cond. lever-magazine prob. diff.3.23.95.42.21.82.02.12.11.91.72.31.7
Pavlov. Cond. response bias4.96.17.72.72.32.62.62.42.52.32.82.0
Pavlov. Cond. lever latency0.30.31.1-0.6-0.7-0.6-1.0-0.1-0.2-0.20.0-0.9
Pavlov. Cond. magazine entry latency2.42.85.41.82.01.82.31.31.31.3-0.22.1
Pavlov. Cond. change in total contacts0.40.61.90.60.60.51.3-0.1-0.1-0.2-1.01.4
Pavlov. Cond. index score1.21.63.61.41.41.41.90.80.90.8-0.21.6
Pavlov. Cond. latency score1.41.94.01.51.61.52.00.91.00.9-0.21.8
Pavlov. Cond. lever contacts0.40.51.50.70.80.71.20.20.30.30.11.0
Pavlov. Cond. magazine entry number1.72.14.5-1.6-1.8-1.6-2.1-0.9-1.0-1.0-0.1-1.9
Pavlov. Cond. intertrial magazine entries1.72.53.6-1.9-1.9-1.9-1.8-1.3-1.6-1.7-0.2-1.1
Pavlov. Cond. lever-magazine prob. diff.1.31.73.71.51.61.51.90.81.00.9-0.21.6
Pavlov. Cond. response bias0.81.02.71.11.11.11.70.60.60.50.31.4
Time in closed arm before self-admin2.43.14.81.81.92.11.61.82.22.20.30.8
Time in closed arm after self-admin1.51.62.21.41.11.51.41.41.51.40.11.1
Time in open arm before self-admin0.60.74.10.40.30.20.30.90.20.22.00.8
Time in open arm after self-admin0.91.02.1-1.0-0.4-1.1-1.5-1.2-1.0-0.7-0.2-1.4
Bone: periosteal estimation2.34.87.3-2.5-1.8-2.4-2.7-2.0-2.2-1.8-1.8-2.4
Bone: periosteal perimeter3.05.29.2-2.3-2.3-2.3-3.0-1.7-1.8-1.6-1.9-3.0
Bone: post-yield work0.50.71.6-1.0-0.8-1.0-0.5-0.3-1.1-1.3-0.60.2
Progressive ratio test 1 active lever presses0.10.10.4-0.2-0.2-0.3-0.4-0.5-0.1-0.1-0.60.3
Progressive ratio test 1 breakpoint0.10.10.3-0.1-0.0-0.1-0.2-0.30.00.0-0.50.5
Progressive ratio test 1 inactive lever presses0.20.30.8-0.5-0.4-0.6-0.7-0.9-0.6-0.5-0.2-0.2
Progressive ratio test 2 active lever presses0.60.72.2-1.1-0.2-0.7-0.4-1.5-1.0-0.9-0.20.3
Progressive ratio test 2 breakpoint0.50.51.9-1.0-0.1-0.6-0.4-1.4-0.9-0.8-0.20.3
Progressive ratio test 2 inactive lever presses0.10.21.00.10.50.30.6-0.50.00.10.11.0
Incentive Sensitization - Responses0.81.12.7-1.4-0.3-1.0-0.5-1.7-1.4-1.3-0.70.1
Incentive Sensitization - Breakpoint0.91.23.1-1.4-0.4-1.0-0.5-1.8-1.4-1.3-0.70.1
Sum of active levers in priming session hrs 5-60.10.10.2-0.40.1-0.3-0.4-0.1-0.3-0.2-0.5-0.4
Progressive ratio0.30.51.50.50.50.50.71.00.50.30.91.2
Food seeking constrained by brief footshock0.60.71.6-0.8-0.9-0.6-0.4-1.1-0.8-0.8-1.2-0.6
Seeking ratio, punishment vs. effort0.50.71.8-0.6-0.7-0.5-0.4-1.2-0.7-0.6-1.4-0.8
Retroperitoneal fat weight1.35.710.7-2.5-3.3-2.3-1.7-2.6-2.5-2.6-1.6-1.9
Reaction time number correct0.81.62.41.21.21.51.21.31.51.50.51.0
Reaction time mean minus median0.10.30.6-0.5-0.8-0.6-0.6-0.1-0.4-0.5-0.4-0.3
Reaction time mean minus median AUC0.51.22.8-1.0-1.1-1.1-1.2-0.7-0.9-0.9-1.7-1.0
Reaction time num false alarms0.10.20.5-0.5-0.3-0.3-0.70.50.10.2-0.0-0.7
Reaction time num false alarms AUC0.10.20.4-0.5-0.3-0.4-0.60.3-0.1-0.0-0.3-0.5
Reaction time trials correct on left0.81.62.41.21.21.51.21.31.51.50.51.0
Reaction time trials on left0.91.72.51.21.31.51.21.41.61.60.51.0
Reaction time mean0.20.21.00.40.10.30.30.50.40.3-1.00.5
Reaction time mean AUC0.20.21.00.40.10.30.30.50.40.2-1.00.6
Median of all reaction times0.30.40.80.70.50.60.60.60.60.5-0.80.9
Reaction time omissions0.10.20.50.20.20.20.20.70.30.2-0.60.7
Reaction time false alarm rate0.40.61.2-0.9-0.8-0.9-1.1-0.2-0.7-0.6-0.3-1.0
Reaction time premature initiation rate0.40.61.7-0.20.2-0.00.7-0.9-0.5-0.6-1.31.3
Reaction time premature initiations0.40.72.80.30.60.61.2-0.20.20.1-1.01.7
Std. dev. reaction times0.20.32.3-0.2-0.7-0.2-0.3-0.1-0.1-0.3-1.5-0.1
Reaction time trials completed0.91.72.51.21.31.51.21.41.61.60.51.0
Reaction time trials AUC0.71.22.01.11.11.31.01.21.41.40.20.9
Run reversals in cocaine runway, females2.42.43.61.91.11.81.21.51.81.91.70.0
Run reversals in cocaine runway, males1.81.84.2-1.4-1.5-1.4-1.6-0.9-1.2-1.1-0.3-2.1
Latency to leave start box in cocaine runway0.50.51.1-0.7-0.5-1.0-0.8-0.7-1.1-0.90.0-0.2
Latency to leave start box in cocaine runway, F0.20.30.6-0.50.0-0.7-0.3-0.4-0.8-0.70.30.2
Latency to leave start box in cocaine runway, M0.70.71.0-0.8-0.9-0.8-1.0-0.7-0.8-0.7-0.9-0.7
Std. dev. time between licks in bursts0.81.11.61.11.31.21.30.91.01.00.41.0
Total sessions with >9 infusions2.73.35.3-1.9-1.7-1.8-1.7-2.1-1.8-1.7-2.3-1.0
Short access day 1 total inactive lever presses3.44.57.8-2.2-2.1-2.1-1.6-2.3-2.3-2.3-2.8-0.6
Short access day 10 total inactive lever presses0.82.03.2-1.4-1.8-1.5-1.3-1.3-1.6-1.5-1.4-0.5
Short access day 1 total infusions1.41.92.7-1.4-1.5-1.4-1.2-1.6-1.4-1.4-1.2-1.0
Short access day 10 total infusions0.10.10.6-0.1-0.2-0.1-0.2-0.4-0.0-0.0-0.80.4
Short access total infusions1.72.13.7-1.5-1.4-1.4-1.4-1.7-1.4-1.3-1.9-0.8
Short access day 1 locomotion0.20.30.6-0.5-0.2-0.6-0.6-0.8-0.7-0.5-0.1-0.3
Short access day 10 total locomotion0.30.61.40.91.20.80.50.70.91.00.30.4
Short access total locomotion0.00.00.20.00.10.0-0.2-0.10.10.2-0.50.1
One hour access (0.3 mA shock)0.20.20.9-0.10.90.20.0-0.40.20.50.20.6
Compulsive drug intake0.30.41.3-0.2-0.1-0.50.3-0.2-0.7-0.90.41.1
One hour access (shock baseline)0.20.30.9-0.10.80.4-0.4-0.30.60.9-0.3-0.5
Social response proportion0.20.20.5-0.2-0.7-0.3-0.2-0.4-0.4-0.5-0.6-0.5
Social responses0.20.30.70.70.30.70.80.30.40.40.10.3
Social time2.43.35.22.11.82.02.32.01.81.6-0.21.6
Soleus weight0.30.81.5-1.0-0.8-1.0-0.5-1.0-1.2-1.2-0.4-0.1
Bone: stiffness0.50.91.5-1.2-1.0-1.1-1.0-0.4-0.9-1.0-1.2-0.4
Tibialis anterior weight0.20.60.90.90.90.91.00.40.70.8-0.20.6
Time to tail flick, vehicle, before self-admin0.50.52.5-0.3-0.7-0.4-0.2-0.5-0.6-0.6-1.6-0.5
Time to tail flick, vehicle, after self-admin0.10.10.30.20.50.2-0.10.60.20.30.6-0.4
Time to tail flick, test, before self-admin0.30.31.5-0.2-0.3-0.2-0.4-0.3-0.1-0.11.2-0.7
Time to tail flick, test, after self-admin0.60.61.40.61.20.70.60.90.80.80.80.6
Delta time to tail flick, vehicle, before/after SA0.70.71.5-0.9-0.2-0.9-0.8-0.7-1.0-0.91.2-0.1
Delta time to tail flick, test, before/after SA0.90.92.20.81.50.91.00.80.80.9-0.21.1
Tibia length0.72.02.9-1.7-1.4-1.5-1.4-1.3-1.3-1.3-1.6-1.0
Ambulatory time before self-admin0.10.20.50.60.30.30.50.60.20.10.70.2
Ambulatory time after self-admin0.10.21.30.3-0.10.20.30.20.10.01.1-0.1
Bone: tissue strength0.50.50.8-0.8-0.4-0.8-0.6-0.7-0.8-0.8-0.9-0.2
Total heroin consumption0.80.91.6-1.1-0.9-1.1-0.7-1.1-1.2-1.30.4-0.3
Bone: trabecular number0.30.62.30.50.70.50.20.80.70.71.50.2
Bone: trabecular spacing1.11.42.6-1.1-1.1-1.1-0.8-1.5-1.3-1.2-1.6-0.6
Bone: trabecular thickness0.70.81.51.20.91.11.20.70.90.90.40.6
Bone: trabecular tissue density0.91.42.31.21.41.31.50.91.01.00.21.5
Water consumed over 24 hours3.14.16.8-2.2-2.6-2.3-2.1-1.9-2.2-2.3-0.8-1.5
Number of responses in last shaping day0.80.91.51.00.91.01.20.60.80.71.11.1