Hub : Genes

LOC102549596

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio XR_005490525.2 0.06 0.04 7.1e-03 0.02 0.02 0.02 0.02 6.1e-03 8.2e-03 2.6e-03 4.4e-03
2 PL alternative polyA XR_005490526.2 0.07 0.03 8.1e-08 0.07 0.06 0.07 0.07 7.7e-08 5.8e-07 1.0e-07 6.4e-08
3 PL alternative polyA XR_005490525.2 0.07 0.03 8.6e-08 0.07 0.06 0.06 0.07 3.8e-08 7.2e-07 1.2e-07 4.1e-08
4 pVTA alternative polyA XR_005490525.2 0.05 0.03 1.6e-03 0.03 0.03 0.03 0.02 1.8e-03 2.0e-03 4.2e-03 8.5e-03
5 PL isoform ratio XR_005490526.2 0.06 0.03 6.8e-05 0.04 0.03 0.03 0.04 9.9e-06 2.4e-04 1.6e-04 1.0e-05
6 NAcc alternative polyA XR_005490525.2 0.08 0.04 3.3e-11 0.09 0.07 0.06 0.07 1.3e-13 1.3e-10 6.1e-10 1.4e-10
7 NAcc alternative polyA XR_005490526.2 0.09 0.04 9.6e-12 0.1 0.08 0.07 0.08 2.3e-14 1.4e-11 6.3e-11 1.1e-11
8 NAcc isoform ratio XR_005490526.2 0.1 0.04 3.3e-13 0.09 0.08 0.08 0.06 8.6e-14 1.0e-12 1.1e-11 2.4e-09
9 PL intron excision ratio chr10_98549126_98557112 0.05 0.03 6.0e-03 0.02 0.01 0.01 0.02 1.4e-03 1.0e-02 7.4e-03 3.7e-03
10 IC intron excision ratio chr10_98549126_98557112 0.26 0.15 1.8e-03 0.03 0.07 0.04 0.01 2.5e-02 6.8e-04 1.1e-02 1.8e-01
11 BLA alternative polyA XR_005490525.2 0.1 0.06 7.1e-05 0.03 0.07 0.01 0.05 1.5e-02 2.1e-04 1.0e-01 1.8e-03
12 BLA alternative polyA XR_005490526.2 0.1 0.06 1.3e-04 0.02 0.06 0.01 0.04 1.8e-02 4.7e-04 9.7e-02 3.6e-03
13 NAcc gene expression LOC102549596 0.07 0.03 7.5e-11 0.06 0.08 0.05 0.07 4.2e-10 1.5e-11 1.8e-08 1.9e-10
14 pVTA alternative polyA XR_005490526.2 0.05 0.03 1.6e-03 0.03 0.03 0.03 0.02 2.7e-03 2.1e-03 3.2e-03 1.0e-02
15 Brain alternative polyA XR_005490526.2 0.03 0.02 1.8e-03 0.02 0.02 0.02 0.02 1.1e-02 5.1e-03 5.8e-03 7.7e-03
16 Brain alternative polyA XR_005490525.2 0.03 0.02 1.7e-03 0.01 0.02 0.02 0.02 1.2e-02 6.0e-03 8.3e-03 1.2e-02
17 Brain isoform ratio XR_005490526.2 0.02 0.01 5.5e-03 0.01 0.02 0 0 2.1e-02 9.6e-03 2.6e-01 1.1e-01
18 Brain gene expression LOC102549596 0.04 0.03 1.2e-03 0.02 0.02 0.02 0.02 2.3e-03 6.5e-03 8.3e-03 1.1e-02
19 OFC gene expression LOC102549596 0.12 0.08 9.9e-03 0.08 0.03 0.02 0.05 5.0e-03 5.4e-02 1.3e-01 2.2e-02
20 PL gene expression LOC102549596 0.09 0.05 1.8e-07 0.05 0.05 0.04 0.04 8.2e-06 9.0e-06 5.0e-05 2.4e-05
21 pVTA gene expression LOC102549596 0.04 0.03 1.4e-03 0.05 0.03 0.03 0.04 9.9e-05 3.2e-03 3.0e-03 4.5e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density0.10.10.4-0.20.3-0.3-0.50.4-0.30.30.30.10.6-0.40.4-0.00.10.2-0.10.10.00.20.00.5
Area under the delay curve2.02.44.21.3-2.02.02.0-1.91.6-1.6-1.6-0.6-2.01.6-1.61.2-1.7-1.71.7-1.61.30.30.70.4
BMI with tail1.03.57.2-2.22.1-2.1-1.72.1-2.62.62.61.12.7-1.51.5-1.41.71.9-1.81.7-1.2-0.6-1.3-0.8
BMI without tail0.31.04.8-0.30.7-0.7-0.00.7-0.80.80.8-0.7-0.5-1.21.2-1.11.01.2-1.21.3-1.0-0.7-1.2-2.2
Body weight0.31.13.20.50.4-0.70.10.1-0.40.40.4-1.6-1.3-1.21.2-1.60.61.1-1.11.2-1.4-1.6-0.5-1.8
Weight adjusted by age0.61.02.1-0.80.8-0.90.21.1-1.41.41.4-0.20.1-0.90.9-0.90.71.0-1.01.0-1.2-0.9-0.4-1.5
Bone surface0.81.46.0-1.30.3-0.3-0.70.4-0.50.50.52.0-0.20.2-0.32.5-0.0-1.11.1-1.21.61.02.41.8
Bone volume0.61.25.1-0.8-0.10.1-0.4-0.1-0.10.10.11.6-0.50.5-0.62.3-0.3-1.31.2-1.21.81.21.91.3
Breakpoint value in progressive ratio session2.02.46.62.6-1.71.72.1-1.62.3-2.3-2.3-2.3-1.41.1-1.1-0.2-1.5-0.91.0-0.90.3-0.50.2-0.2
Number of licking bursts2.03.38.1-0.0-1.41.11.0-1.51.2-1.2-1.21.4-1.62.4-2.42.8-1.3-2.42.4-2.42.52.02.20.9
Context. condit. distance diff. score0.50.61.5-0.40.5-0.3-0.30.5-0.70.70.7-0.11.1-0.90.9-1.20.51.0-1.00.9-1.0-0.8-0.90.4
Locomotion velocity, session 10.80.83.91.4-0.70.20.5-0.91.4-1.4-1.4-1.1-2.00.5-0.50.5-0.6-0.70.7-0.60.50.20.7-0.1
Locomotion distance, session 11.41.74.40.80.5-0.8-0.30.20.0-0.0-0.0-1.7-1.5-1.41.4-1.81.01.4-1.41.6-1.8-2.0-1.7-2.1
Locomotion velocity, session 20.60.71.80.80.8-1.2-1.20.50.3-0.3-0.3-1.3-0.4-0.80.8-0.60.90.8-0.80.8-0.9-1.3-0.6-0.6
Locomotion distance, session 22.23.18.00.51.3-1.6-1.30.9-0.50.50.5-1.7-1.1-2.02.0-2.01.92.1-2.12.2-2.5-2.8-2.0-2.3
Locomotion velocity, session 30.40.51.50.7-0.10.40.5-0.10.2-0.2-0.2-1.1-0.7-0.80.8-1.20.20.7-0.70.8-1.0-0.6-1.2-0.9
Locomotion distance, session 32.42.74.5-0.41.9-2.1-1.61.5-1.11.11.1-0.70.9-1.81.8-1.71.92.0-2.02.0-2.1-1.9-1.9-1.0
Stereotopy head waving bouts, day 30.30.42.10.3-0.60.60.6-0.60.5-0.5-0.50.30.60.6-0.6-0.0-0.9-0.50.6-0.60.71.4-0.00.7
Stereotopy head waving duration, day 30.40.42.4-0.4-0.20.2-0.2-0.30.2-0.2-0.21.10.60.7-0.70.7-0.5-0.60.7-0.71.01.50.50.8
Locomotion velocity, session 72.12.34.0-0.21.7-1.8-1.91.4-0.80.80.8-0.70.3-1.91.9-1.32.01.8-1.81.9-1.5-1.9-1.5-1.3
Locomotion distance, session 77.29.117.9-1.03.1-3.1-3.02.8-2.42.42.4-1.10.9-3.33.3-2.83.63.6-3.73.7-3.6-4.2-3.6-2.8
Stereotopy head waving bouts, day 70.91.05.10.2-0.91.00.8-0.80.5-0.5-0.50.30.90.6-0.60.4-1.4-0.91.0-1.10.91.61.52.3
Stereotopy head waving duration, day 72.12.58.3-0.2-0.90.70.5-0.80.6-0.6-0.61.31.31.5-1.51.6-1.7-1.71.8-1.92.12.82.42.9
Locomotion velocity, session 80.10.20.80.20.4-0.4-0.90.10.2-0.2-0.2-0.3-0.7-0.10.0-0.10.70.3-0.30.3-0.4-0.3-0.2-0.9
Locomotion distance, session 83.14.47.9-0.62.0-2.1-1.91.7-1.51.51.5-0.80.4-2.62.6-2.32.52.7-2.72.7-2.8-2.8-2.3-1.7
Degree of sensitization distance1.21.23.3-0.60.9-0.6-0.91.1-1.11.11.1-0.10.0-1.21.2-0.81.31.2-1.31.3-1.2-1.8-1.1-1.5
Degree of sensitization stereotypy0.70.84.30.0-0.70.70.6-0.60.2-0.2-0.20.30.90.5-0.50.4-1.2-0.80.8-0.90.81.21.62.1
Conditioned locomotion0.30.31.7-1.10.3-0.2-0.40.3-0.80.80.81.30.50.2-0.20.50.1-0.20.1-0.20.40.90.2-0.1
Cocaine response after cond. corrected0.40.51.40.3-0.81.01.1-0.70.4-0.4-0.4-0.10.51.1-1.1-0.1-1.2-0.70.8-0.8-0.00.20.90.8
Cocaine response after cond. not corrected0.30.30.90.7-0.81.00.7-0.70.4-0.4-0.4-0.6-0.50.6-0.5-0.4-0.7-0.30.3-0.3-0.5-0.40.5-0.0
Cocaine response before conditioning1.31.63.4-0.10.9-0.9-1.50.6-0.90.90.9-0.6-1.1-1.81.8-1.01.61.4-1.51.6-1.3-1.4-1.2-1.4
Saline control response0.40.52.1-0.20.3-0.30.10.5-0.40.40.4-0.1-0.6-1.51.5-0.90.50.9-0.90.9-1.0-1.1-0.4-0.3
Bone: connectivity density0.50.71.9-1.11.2-1.3-1.11.3-1.01.01.00.81.4-0.60.60.10.60.4-0.40.3-0.3-0.20.30.7
Bone: cortical apparent density0.71.03.11.5-1.11.11.4-1.00.8-0.8-0.8-1.8-0.70.4-0.3-1.5-0.90.1-0.10.2-0.8-0.3-1.5-0.8
Bone: cortical area3.45.28.6-2.52.5-2.4-2.52.4-2.92.92.91.42.7-2.92.9-1.52.12.3-2.32.1-1.8-1.3-0.20.9
Bone: cortical porosity0.40.52.9-0.1-0.20.0-0.3-0.30.4-0.4-0.40.8-0.5-0.10.11.3-0.1-0.60.6-0.51.31.70.90.7
Bone: cortical porosity0.70.83.7-0.1-0.40.3-0.1-0.50.6-0.6-0.61.0-0.60.3-0.31.6-0.3-0.90.9-0.91.61.91.10.9
Bone: cortical thickness4.87.930.00.21.3-0.9-0.61.2-1.81.81.8-2.32.5-4.24.2-5.51.23.8-3.63.6-4.2-2.8-2.9-0.0
Bone: cortical thickness1.72.16.70.10.7-0.3-0.50.9-0.90.90.9-1.11.7-2.12.2-2.60.71.9-1.81.8-2.0-1.1-1.70.4
Bone: cortical tissue density0.81.13.01.6-1.31.31.6-1.21.0-1.0-1.0-1.7-0.80.6-0.6-1.3-1.0-0.10.10.0-0.6-0.1-1.3-0.7
Condit. Reinf. active minus inactive responses2.52.85.5-1.52.1-1.9-1.42.4-1.81.81.80.62.1-1.61.6-1.41.71.9-1.91.8-1.6-1.6-1.2-0.6
Condit. Reinf. active-inactive response ratio3.33.58.9-2.12.3-2.1-1.82.7-2.32.32.31.23.0-1.41.4-1.11.71.8-1.81.6-1.3-1.3-1.0-0.2
Condit. Reinf. active responses1.72.13.5-0.71.5-1.2-0.81.7-1.31.31.3-0.31.3-1.51.5-1.81.31.8-1.81.7-1.9-1.8-1.6-1.0
Condit. Reinf. inactive responses0.70.83.11.4-0.50.70.8-0.60.7-0.7-0.7-1.8-1.5-0.50.6-1.1-0.10.4-0.50.6-1.0-1.1-1.0-1.1
Incentive salience index mean1.11.42.6-0.91.4-1.2-0.71.6-1.21.21.20.21.3-1.11.1-1.21.11.4-1.41.3-1.3-1.4-1.0-0.7
Condit. Reinf. lever presses0.70.92.8-0.10.6-0.40.10.8-0.80.80.8-0.70.1-1.01.0-1.40.71.2-1.21.2-1.4-1.7-1.2-1.2
Condit. Reinf. active minus inactive responses0.30.42.1-0.20.8-0.7-1.20.7-0.20.20.20.11.1-0.80.8-0.00.60.4-0.40.30.00.10.51.4
Condit. Reinf. active-inactive response ratio0.10.10.60.20.4-0.3-0.70.40.3-0.3-0.3-0.20.0-0.20.20.30.40.1-0.10.10.2-0.00.10.3
Condit. Reinf. active responses0.81.12.3-0.61.2-1.1-1.41.0-1.01.01.0-0.01.0-1.51.5-0.81.21.2-1.21.1-0.9-1.0-0.20.6
Condit. Reinf. inactive responses1.41.84.1-0.91.1-1.1-1.01.0-1.61.61.60.11.1-2.02.0-1.51.21.6-1.61.6-1.3-1.2-0.80.3
Condit. Reinf. lever presses1.62.24.4-1.32.0-1.9-2.11.8-1.61.61.60.71.0-1.81.8-0.52.01.5-1.61.5-1.1-1.3-0.6-0.3
Condit. Reinf. lever reinforcers received1.21.73.3-0.81.6-1.5-1.71.4-1.31.31.30.01.1-1.81.8-0.91.61.5-1.51.4-1.2-1.4-0.40.2
Conditioned reinforcement - actives0.61.02.8-1.11.3-1.4-1.41.2-1.21.21.20.61.7-0.80.8-0.41.00.9-0.90.7-0.4-0.2-0.20.2
Conditioned reinforcement - inactives3.45.07.7-2.42.7-2.4-2.42.8-2.72.72.71.42.3-2.32.3-1.22.72.4-2.42.3-1.6-1.1-1.8-1.3
Conditioned locomotion0.30.40.8-0.60.7-0.9-0.70.6-0.90.90.90.20.8-0.70.8-0.60.60.7-0.70.6-0.50.0-0.2-0.2
Patch foraging indifference point 0 sec2.64.87.4-0.82.2-2.2-2.02.1-2.22.22.2-0.81.1-2.72.7-2.32.22.7-2.72.6-2.6-2.6-1.4-1.7
Patch foraging indifference point AUC0.81.13.0-1.71.3-1.3-1.31.4-1.31.31.31.30.1-0.30.30.51.40.6-0.60.6-0.2-0.6-0.3-1.6
Delay disc. indifference point, 0s delay0.30.31.50.8-0.60.51.1-0.50.2-0.2-0.2-1.2-0.10.1-0.1-0.6-0.8-0.20.2-0.2-0.4-0.00.20.3
Delay disc. indifference point, 16s delay0.80.91.70.8-1.11.31.2-0.91.1-1.1-1.1-0.1-1.20.9-0.91.0-0.9-1.11.0-1.00.80.10.70.3
Delay disc. indifference point, 2s delay4.85.410.92.1-3.02.93.1-2.82.5-2.5-2.5-0.9-3.32.3-2.21.6-2.5-2.52.4-2.22.01.31.10.2
Delay disc. indifference point, 24s delay0.70.82.80.5-1.00.80.6-1.01.0-1.0-1.00.2-1.70.8-0.81.2-0.7-1.11.0-0.91.00.00.9-0.1
Delay disc. indifference point, 4s delay3.03.15.01.3-2.22.12.0-2.11.9-1.9-1.9-0.3-1.22.1-2.11.2-2.2-2.12.1-2.01.81.31.01.1
Delay disc. indifference point, 8s delay1.51.83.41.0-1.81.81.8-1.71.3-1.3-1.3-0.4-1.41.5-1.51.0-1.6-1.51.5-1.41.30.10.40.5
Indifference point function ln k0.71.13.5-0.40.4-0.4-0.30.3-1.11.11.1-0.01.3-1.51.5-1.90.41.4-1.31.2-1.5-0.9-1.10.5
Indifference point function log k0.71.13.5-0.40.4-0.4-0.30.3-1.11.11.1-0.01.3-1.51.5-1.90.41.4-1.31.2-1.5-0.9-1.10.5
Patch foraging total patch changes 0 sec2.64.87.8-0.82.2-2.2-2.02.0-2.12.12.1-0.81.1-2.82.8-2.42.22.7-2.72.7-2.7-2.7-1.4-1.7
Patch foraging total patch changes 12 sec2.53.36.4-0.92.1-2.1-2.52.1-1.71.71.7-0.40.4-2.22.2-1.32.22.1-2.12.1-1.7-2.0-0.8-1.8
Patch foraging total patch changes 18 sec1.42.14.5-0.21.4-1.5-1.11.2-1.11.11.1-0.90.5-1.71.7-1.81.41.8-1.81.8-2.0-2.1-1.1-1.4
Patch foraging total patch changes 24 sec1.93.37.1-1.42.4-2.4-2.72.4-1.91.91.90.21.6-2.02.0-0.82.21.9-1.91.8-1.4-1.4-0.3-0.8
Patch foraging total patch changes 6 sec3.65.411.8-1.32.3-2.3-1.92.2-2.22.22.2-0.40.1-2.72.7-2.02.72.8-2.82.9-2.5-2.8-2.0-3.4
Patch foraging time to switch 0 sec0.81.52.31.4-1.41.50.8-1.41.5-1.5-1.5-0.8-1.41.2-1.21.1-1.1-1.41.3-1.31.21.10.60.8
Patch foraging water rate 0 sec0.61.32.1-1.11.2-1.3-0.31.3-1.41.41.40.50.8-1.21.2-1.01.11.3-1.31.2-1.1-1.2-0.6-1.0
Patch foraging water rate 12 sec0.20.31.50.4-0.10.20.90.0-0.10.10.1-0.80.8-0.50.5-1.2-0.20.6-0.50.5-1.0-0.9-0.20.3
Patch foraging water rate 18 sec0.61.03.8-1.21.0-0.9-0.51.3-1.21.21.21.02.0-0.90.9-0.60.80.9-0.90.8-0.4-0.7-0.70.2
Patch foraging water rate 24 sec3.65.18.2-1.32.1-2.1-1.62.0-2.02.02.00.42.8-2.72.7-2.82.02.9-2.82.7-2.5-2.3-2.7-0.7
Patch foraging water rate 6 sec0.60.94.11.3-0.1-0.20.6-0.40.5-0.5-0.5-1.9-0.3-0.90.9-2.0-0.20.9-0.90.9-1.4-1.2-0.8-0.5
Seeking ratio, delayed vs. immediate footshock0.40.51.9-0.80.00.00.10.2-0.20.20.21.40.40.4-0.41.2-0.3-0.70.7-0.71.11.41.00.7
Distance traveled before self-admin0.60.81.80.8-1.11.41.1-1.00.8-0.8-0.8-0.40.21.1-1.10.2-1.3-0.91.0-1.00.50.60.80.9
Distance traveled after self-admin0.10.10.6-0.30.5-0.5-0.10.8-0.20.20.20.20.60.2-0.20.10.30.1-0.20.1-0.20.1-0.3-0.5
Extensor digitorum longus weight0.10.41.4-0.10.4-0.5-0.60.3-0.50.50.5-0.5-0.1-0.10.2-0.90.40.6-0.60.6-0.9-1.1-0.7-1.2
Bone: elastic displacement1.31.57.20.9-0.10.20.6-0.2-0.20.20.2-1.80.3-1.71.8-2.7-0.01.5-1.41.4-2.0-1.4-1.2-0.3
Bone: elastic work2.83.68.7-0.41.6-1.5-1.01.5-1.41.41.4-0.71.8-2.93.0-2.91.32.5-2.52.4-2.5-1.6-1.7-0.2
Bone: endosteal estimation3.98.532.3-4.82.9-3.1-3.83.0-2.92.92.95.71.40.7-0.85.02.2-1.10.9-1.22.61.53.11.1
Bone: endosteal perimeter3.47.231.8-3.81.6-1.9-2.31.6-1.61.61.65.20.11.8-1.85.61.0-2.22.0-2.23.42.14.11.2
Epididymis fat weight1.65.313.41.30.6-0.40.20.7-0.30.30.3-3.2-1.8-2.52.5-3.31.42.6-2.62.8-3.4-3.7-3.4-3.5
Delta time in closed arm before/after self-admin0.30.21.40.30.5-0.5-1.20.20.2-0.2-0.2-0.4-0.0-0.50.50.00.90.4-0.50.5-0.20.7-0.5-0.1
Delta time in open arm before/after self-admin1.01.02.90.9-0.81.11.6-0.70.4-0.4-0.4-1.1-1.3-0.91.0-1.7-0.40.7-0.70.8-1.1-1.5-1.0-0.8
Diff in mean of infusions in LGA sessions0.50.62.81.1-0.70.71.7-0.71.0-1.0-1.0-0.8-0.00.8-0.7-0.4-0.9-0.30.4-0.4-0.10.6-0.3-0.3
Delay discount exponential model param2.73.05.1-1.32.3-2.2-2.22.1-1.81.81.80.42.1-1.91.8-1.41.92.0-1.91.8-1.6-0.5-0.8-0.5
Extinction: sum of active levers before priming1.01.11.90.41.1-0.9-1.10.9-0.10.10.1-1.00.4-1.31.3-1.01.41.4-1.41.4-1.3-1.0-1.0-1.0
Active lever presses in extinction session 61.51.52.51.2-1.21.11.6-1.21.4-1.4-1.4-0.7-1.61.3-1.31.0-1.2-1.31.3-1.21.10.11.3-0.2
Bone: final force4.47.012.9-3.13.2-2.9-3.33.2-3.33.33.32.03.6-3.02.9-1.22.52.5-2.42.2-1.6-1.1-0.51.1
Bone: final moment4.16.512.1-2.72.9-2.6-3.13.0-3.13.13.11.63.5-3.13.1-1.72.32.6-2.52.3-1.9-1.3-0.71.1
Food consumed during 24 hour testing period0.20.21.1-0.4-0.20.10.2-0.2-0.20.20.20.7-0.70.3-0.30.8-0.2-0.50.5-0.50.51.00.70.4
Glucose0.30.41.11.0-0.70.50.4-0.80.9-0.9-0.9-0.9-0.70.4-0.40.1-0.6-0.50.5-0.40.30.60.20.4
Heart weight1.72.65.2-0.81.6-1.4-1.01.7-1.51.51.5-0.50.4-2.32.3-1.71.52.0-2.02.0-2.0-2.3-0.9-1.1
Delay discount hyperbolic model param3.53.86.4-1.62.5-2.5-2.42.4-2.12.12.10.62.3-2.12.1-1.52.22.2-2.22.1-1.8-0.7-1.0-0.6
Intermittent access intake day 1-15 change0.10.31.30.6-0.50.41.1-0.40.2-0.2-0.2-0.80.20.00.0-1.1-0.70.2-0.10.1-0.70.1-0.50.1
Intermittent access intake escalation0.10.21.50.5-0.0-0.00.80.10.1-0.1-0.1-0.80.5-0.20.2-1.2-0.40.4-0.40.4-0.80.0-0.60.1
Intermittent access intake escalation 20.91.13.61.5-1.31.21.9-1.11.1-1.1-1.1-1.4-0.80.8-0.8-0.6-1.5-0.70.7-0.7-0.10.70.30.1
Intermitt. access day 1 inactive lever presses2.28.513.8-1.72.7-2.5-2.12.6-2.72.72.70.21.8-3.73.7-3.13.13.7-3.73.6-3.3-3.7-3.1-2.2
Intermitt. access day 15 inactive lever presses0.10.20.6-0.20.00.30.10.2-0.40.40.40.1-0.4-0.60.6-0.30.40.5-0.50.5-0.4-0.4-0.8-0.6
Intermitt. access escalation Index0.10.10.7-0.4-0.10.1-0.2-0.0-0.00.00.00.90.40.3-0.30.5-0.1-0.30.3-0.40.40.20.40.5
Intermittent access day 1 total infusions3.15.08.5-2.92.8-2.8-2.72.7-2.92.92.92.21.8-2.22.1-0.32.82.0-2.01.9-0.9-1.6-0.9-1.1
Intermittent access day 15 total infusions2.23.35.4-2.12.2-2.3-1.52.3-2.32.32.31.41.7-1.81.8-1.01.91.9-1.91.8-1.3-0.9-1.1-1.0
Intermittent access terminal intake (last 3 days)1.92.54.5-2.12.0-2.0-1.52.0-2.12.12.11.61.7-1.41.4-0.51.71.4-1.41.3-0.9-0.8-0.5-0.6
Intermittent access total infusions5.46.410.6-3.23.1-3.2-2.73.1-3.33.33.32.32.1-2.32.3-0.73.02.4-2.42.3-1.4-1.5-1.4-1.5
Intermittent access day 1 locomotion2.43.05.9-2.42.0-2.1-2.01.9-2.42.42.42.01.1-1.71.7-0.12.01.5-1.51.4-0.6-1.3-0.4-1.0
Intermittent access day 15 total locomotion2.03.65.6-1.62.2-2.4-1.42.2-2.12.12.10.61.3-2.32.3-1.61.92.2-2.22.1-1.7-1.5-1.1-1.4
Intermittent access total locomotion4.14.98.5-2.52.7-2.9-2.42.6-2.82.82.81.71.5-2.32.3-0.82.62.2-2.22.2-1.3-1.3-1.1-1.5
Intermittent access standard deviation0.61.23.4-1.81.2-1.1-0.71.4-1.71.71.71.61.6-0.50.5-0.20.70.7-0.70.6-0.50.1-0.20.1
Left kidney weight0.00.21.70.00.1-0.10.20.20.0-0.0-0.0-0.10.80.1-0.10.0-0.5-0.30.3-0.40.50.11.30.9
Right kidney weight0.00.20.8-0.20.0-0.30.50.3-0.30.30.3-0.10.90.1-0.1-0.3-0.8-0.20.2-0.30.2-0.10.80.6
Cocaine induced anxiety0.20.21.00.3-0.71.00.0-0.60.3-0.3-0.3-0.1-1.00.1-0.1-0.2-0.1-0.10.00.0-0.1-1.0-0.1-0.6
Post-drug Anxiety0.30.31.40.4-0.30.6-0.4-0.40.2-0.2-0.2-0.6-1.2-0.50.5-0.70.40.5-0.50.6-0.7-0.7-0.5-1.0
Baseline Anxiety0.20.20.6-0.00.6-0.8-0.50.5-0.30.30.3-0.4-0.2-0.60.6-0.20.70.5-0.50.5-0.40.4-0.4-0.4
Tail length0.93.520.03.0-1.71.52.0-1.92.2-2.2-2.2-3.4-4.5-0.20.2-0.8-0.8-0.30.20.1-0.6-1.0-0.2-1.9
Length with tail1.14.820.53.5-2.42.12.5-2.62.7-2.7-2.7-3.7-4.50.5-0.5-0.6-1.8-1.01.0-0.7-0.2-1.01.1-1.1
Length without tail0.82.66.12.5-1.91.81.7-2.02.0-2.0-2.0-2.4-1.51.0-1.0-0.5-2.1-1.21.2-1.20.1-0.71.61.0
Times rat made contact with spout3.43.98.82.2-2.42.32.4-2.32.5-2.5-2.5-1.1-3.01.7-1.71.1-1.9-1.91.8-1.61.41.90.6-0.2
Lifetime Intake5.76.912.3-3.53.3-3.2-3.03.3-3.43.43.42.72.5-2.32.3-0.63.02.3-2.42.2-1.2-1.5-1.2-1.1
Liver weight, left0.30.63.21.2-0.60.60.5-0.70.8-0.8-0.8-1.3-1.8-0.40.4-0.1-0.4-0.20.1-0.1-0.3-1.10.4-0.2
Liver weight, right0.40.61.6-0.50.7-0.6-0.50.8-0.90.90.9-0.10.9-1.31.3-0.90.50.9-0.90.9-0.7-0.5-0.30.1
Locomotor activity0.81.22.6-1.21.2-1.1-1.11.1-1.21.21.20.80.5-0.70.7-0.41.61.1-1.21.1-1.0-0.8-1.6-1.6
Locomotor testing distance2.13.97.9-1.21.7-1.4-1.21.7-1.91.91.90.20.8-2.02.0-1.92.42.4-2.42.4-2.4-1.9-2.8-2.5
Locomotor testing rearing0.71.53.4-0.51.0-0.7-0.41.2-1.01.01.0-0.00.2-1.31.3-1.31.31.5-1.51.5-1.7-1.6-1.4-1.8
Locomotion in novel chamber0.40.61.30.3-0.40.30.2-0.40.7-0.7-0.70.3-1.00.9-1.01.1-0.3-0.90.8-0.81.11.00.8-0.5
Locomotion in novel chamber post-restriction0.40.61.60.30.5-0.3-0.90.6-0.10.10.1-0.7-0.2-1.11.1-0.51.11.0-1.01.0-0.6-0.2-1.3-1.1
Fecal boli incidents, locomotor time 10.10.10.3-0.10.3-0.4-0.50.1-0.30.30.3-0.0-0.3-0.40.4-0.00.50.3-0.30.4-0.2-0.2-0.5-0.3
Change in fecal boli incidents, locomotor task0.30.30.8-0.50.10.20.20.3-0.70.70.70.00.9-0.40.4-0.90.00.6-0.50.5-0.9-0.5-0.90.1
Time >=10cm from walls, locomotor time 10.50.52.5-0.80.8-0.9-1.20.9-0.50.50.50.81.60.2-0.20.60.3-0.10.1-0.30.30.20.81.1
Bouts of movement, locomotor time 10.81.03.40.00.2-0.2-0.20.1-0.50.50.5-0.7-1.2-1.01.0-1.10.91.1-1.11.2-1.2-1.2-1.7-1.9
Total resting periods, locomotor time 10.40.52.10.5-0.20.10.2-0.40.1-0.1-0.1-0.9-1.5-0.50.5-0.80.40.5-0.50.7-0.7-0.7-1.2-1.4
Rest time, locomotor task time 10.20.30.70.7-0.60.30.6-0.80.6-0.6-0.6-0.6-0.20.3-0.3-0.2-0.8-0.40.5-0.40.10.10.40.6
Distance moved, locomotor task time 10.10.21.10.4-0.71.00.7-0.40.5-0.5-0.5-0.3-0.60.3-0.3-0.0-0.3-0.20.2-0.10.20.4-0.5-0.3
Vertical activity count, locomotor time 11.12.74.6-1.51.8-1.3-1.32.1-1.81.81.80.60.5-1.91.9-0.92.21.9-1.91.9-1.3-1.2-1.6-1.6
Time >=10cm from walls, locomotor time 20.40.61.80.30.10.1-0.20.1-0.10.10.1-0.6-0.6-0.80.8-1.10.60.9-0.91.0-1.0-1.0-1.3-1.3
Bouts of movement, locomotor time 20.50.91.91.4-1.01.01.3-1.01.2-1.2-1.2-1.4-1.40.5-0.4-0.5-0.5-0.20.2-0.0-0.1-0.2-1.3-1.0
Total resting periods, locomotor time 20.40.72.11.2-0.80.71.2-0.81.0-1.0-1.0-1.2-1.40.4-0.4-0.4-0.3-0.10.10.1-0.1-0.1-1.4-1.4
Rest time, locomotor task time 20.00.10.50.20.2-0.2-0.10.3-0.10.10.1-0.40.7-0.10.1-0.2-0.00.1-0.10.00.00.20.10.4
Distance moved, locomotor task time 20.10.10.6-0.1-0.50.70.4-0.30.1-0.1-0.10.3-0.70.2-0.20.1-0.2-0.20.2-0.20.10.10.1-0.1
Vertical activity count, locomotor time 20.70.91.9-0.70.9-0.8-0.61.1-1.11.11.10.20.5-1.31.3-0.90.91.1-1.11.1-1.0-1.4-0.5-0.3
Light reinforcement 11.43.36.1-2.22.1-1.8-2.12.5-2.52.52.51.42.1-1.61.6-0.91.81.8-1.71.6-1.4-1.0-0.7-1.0
Light reinforcement 20.91.43.5-1.91.5-1.4-1.81.6-1.51.51.51.70.6-0.80.80.61.50.7-0.70.7-0.0-0.20.3-0.8
Bone: marrow area3.88.331.1-4.83.0-3.1-3.83.0-2.92.92.95.61.40.6-0.74.82.3-1.00.8-1.12.51.43.01.1
Bone: maximum diameter3.46.321.3-4.42.7-2.9-3.32.6-3.13.13.14.62.3-0.40.32.81.9-0.10.1-0.41.40.72.51.8
Bone: maximum force4.17.312.9-3.23.4-3.1-3.63.5-3.53.53.52.03.1-2.92.9-0.92.82.4-2.42.2-1.6-1.3-0.40.6
Bone: maximum moment3.86.610.6-2.83.1-2.7-3.33.1-3.23.23.21.63.0-3.03.0-1.32.62.5-2.52.3-1.9-1.5-0.60.6
Mean time between licks in bursts0.10.11.10.10.4-0.6-1.10.30.2-0.2-0.2-0.0-0.4-0.10.10.50.4-0.10.0-0.00.3-0.10.3-0.1
Mean num. licks in bursts1.21.96.11.00.3-0.10.00.5-0.10.10.1-1.90.1-1.81.8-2.50.61.7-1.71.8-2.1-1.1-2.2-1.3
Cd content in liver1.41.54.60.20.4-0.2-0.30.3-0.50.50.5-0.9-0.3-1.51.5-2.10.91.6-1.61.7-2.1-1.5-2.1-1.4
Co content in liver1.21.42.90.5-1.61.71.5-1.51.2-1.2-1.20.4-0.41.5-1.50.6-1.5-1.21.2-1.21.11.3-0.10.2
Cu content in liver1.11.34.2-0.1-0.80.70.6-0.70.5-0.5-0.50.80.11.3-1.31.4-1.3-1.41.4-1.51.41.02.11.6
Fe content in liver1.01.23.1-0.01.1-1.1-0.90.8-0.70.70.7-0.90.6-1.61.6-1.51.01.4-1.41.4-1.8-1.2-0.9-0.3
K content in liver2.12.13.41.4-1.61.51.0-1.81.8-1.8-1.8-0.5-1.41.8-1.71.1-1.2-1.51.5-1.41.51.50.20.2
Mg content in liver0.80.81.70.3-1.00.90.7-0.90.7-0.7-0.70.3-0.61.2-1.21.1-0.8-1.11.0-1.01.11.3-0.00.3
Mn content in liver1.51.75.6-1.2-0.30.20.1-0.2-0.10.10.12.40.70.9-1.02.1-0.7-1.41.4-1.42.02.21.71.8
Na content in liver2.02.24.81.1-1.51.51.1-1.41.6-1.6-1.6-0.0-0.82.2-2.21.6-1.4-1.81.8-1.81.70.41.00.5
Rb content in liver0.91.12.9-1.71.0-0.9-0.71.4-1.71.71.71.21.7-0.20.2-0.10.70.6-0.60.4-0.3-0.7-0.40.1
Se content in liver0.60.71.60.0-1.00.91.1-0.80.6-0.6-0.60.7-1.01.3-1.30.9-0.6-0.90.9-0.80.91.0-0.8-0.7
Sr content in liver0.50.42.5-0.50.7-0.9-0.70.7-0.50.50.50.2-0.5-0.30.20.21.00.4-0.50.5-0.3-0.3-0.6-1.6
Zn content in liver1.01.12.20.5-1.00.81.0-0.91.0-1.0-1.00.20.21.5-1.50.7-1.4-1.21.3-1.31.01.00.61.2
Bone: minimum diameter2.03.713.6-3.01.8-2.0-2.11.7-1.71.71.73.71.50.1-0.13.01.1-0.70.6-0.81.81.42.91.8
Time in familiar zone, hab. session 11.51.42.8-0.20.8-0.7-0.20.8-1.01.01.0-0.60.6-1.71.7-1.71.01.5-1.51.5-1.6-1.6-1.6-0.4
Time in novel zone, hab. session 10.40.41.1-0.7-0.10.1-0.10.1-0.30.30.31.00.40.9-0.90.9-0.5-0.80.8-0.80.90.91.00.4
Total zone transitions, hab. session 10.70.94.20.6-0.2-0.10.2-0.30.0-0.0-0.0-1.2-2.0-0.80.8-1.20.40.8-0.81.0-1.3-1.8-0.8-1.7
Total locomotion distance, hab. session 11.42.03.9-1.11.3-1.4-0.81.4-1.51.51.50.30.1-1.71.7-1.31.41.7-1.71.7-1.8-2.0-1.1-1.4
Locomotion velocity, hab. session 10.81.22.8-0.60.8-0.8-0.60.8-0.90.90.90.1-0.7-1.31.3-0.91.21.2-1.31.4-1.4-1.7-0.8-1.6
Time in familiar zone, hab. session 20.70.82.31.5-0.91.01.1-0.91.3-1.3-1.3-1.4-0.90.6-0.6-0.2-0.6-0.40.4-0.30.10.1-0.2-0.6
Time in novel zone, hab. session 22.72.76.5-2.41.9-1.9-2.21.7-2.22.22.22.02.6-1.31.3-0.41.31.1-1.10.9-0.5-0.1-0.31.3
Total zone transitions, hab. session 20.50.61.80.30.5-0.6-0.40.3-0.00.00.0-0.8-1.0-0.70.7-0.80.90.9-0.91.0-1.1-1.2-1.1-1.3
Total locomotion distance, hab. session 20.40.51.0-0.40.8-0.9-0.60.7-0.40.40.40.1-0.1-0.70.7-0.60.90.8-0.90.9-0.8-0.9-0.9-1.0
Locomotion velocity, hab. session 20.20.20.7-0.30.6-0.7-0.40.5-0.20.20.20.3-0.2-0.30.3-0.30.60.5-0.50.5-0.5-0.7-0.5-0.8
Novel to familiar place preference ratio0.10.10.60.2-0.30.50.5-0.20.2-0.2-0.20.00.00.3-0.30.3-0.3-0.30.3-0.30.30.8-0.10.0
Novelty place preference0.10.10.50.1-0.20.30.2-0.00.1-0.1-0.10.10.30.3-0.20.3-0.2-0.20.2-0.30.20.7-0.20.1
Time in novel zone, NPP test0.10.10.4-0.10.20.1-0.10.3-0.20.20.2-0.00.5-0.30.3-0.20.30.3-0.30.2-0.30.3-0.6-0.2
Total zone transitions, NPP test1.52.17.01.10.5-0.8-0.60.10.2-0.2-0.2-1.9-2.0-1.81.8-1.91.21.6-1.61.8-2.0-2.7-1.1-1.6
Total locomotion distance, NPP test3.14.210.20.31.5-1.5-1.31.2-0.70.70.7-1.4-0.8-2.92.9-2.72.02.6-2.62.8-2.9-3.2-1.9-1.9
Locomotion velocity, NPP test1.72.47.00.60.9-1.0-0.60.6-0.20.20.2-1.5-1.0-2.22.2-2.21.41.9-2.02.1-2.3-2.6-1.3-1.6
Intraocular pressure0.50.81.7-0.41.1-1.3-1.00.7-0.70.70.7-0.2-0.3-1.11.1-0.41.31.0-1.01.0-1.0-0.5-0.6-0.8
Delta distance traveled before/after self-admin2.52.77.7-2.02.4-2.8-1.62.5-1.81.81.81.41.5-1.11.1-0.12.01.4-1.41.3-0.8-0.4-1.1-1.3
Delta ambulatory time before/after self-admin1.01.24.2-1.71.7-2.0-1.12.0-1.11.11.11.61.2-0.10.10.91.20.4-0.40.30.30.1-0.3-0.5
Parametrial fat weight0.30.71.6-0.71.0-1.3-0.80.8-0.70.70.70.50.0-0.80.8-0.51.10.9-0.91.0-0.6-0.6-1.0-1.2
Pavlov. Cond. lever latency0.60.82.2-1.21.2-1.1-1.51.1-1.01.01.01.21.3-0.40.40.20.90.5-0.50.4-0.3-0.3-0.10.6
Pavlov. Cond. magazine entry latency1.01.33.21.0-1.31.31.7-1.01.2-1.2-1.2-0.50.61.1-1.10.1-1.8-1.11.1-1.20.81.01.11.6
Pavlov. Cond. change in total contacts0.40.42.21.1-0.20.20.4-0.20.5-0.5-0.5-1.50.0-0.50.5-1.2-0.10.5-0.50.5-0.8-0.6-0.6-0.3
Pavlov. Cond. index score0.70.82.11.0-1.11.11.5-0.91.0-1.0-1.0-0.6-0.20.9-0.90.2-1.3-0.90.9-0.90.70.80.70.4
Pavlov. Cond. latency score1.11.33.21.3-1.51.41.8-1.31.3-1.3-1.3-0.8-0.71.0-1.00.3-1.6-1.11.1-1.10.80.90.80.4
Pavlov. Cond. lever contacts0.40.51.61.1-0.80.91.2-0.70.7-0.7-0.7-1.3-0.90.1-0.0-0.5-0.6-0.10.1-0.0-0.10.0-0.2-0.8
Pavlov. Cond. magazine entry number0.60.72.1-0.80.9-1.0-1.40.6-0.80.80.80.5-0.8-0.60.60.31.40.6-0.70.7-0.4-0.5-0.8-1.5
Pavlov. Cond. intertrial magazine entries1.21.43.20.10.9-0.8-1.00.8-0.60.60.6-1.0-0.7-1.31.3-1.31.31.4-1.41.5-1.7-1.4-1.6-1.8
Pavlov. Cond. lever-magazine prob. diff.0.60.71.80.7-1.01.01.4-0.80.9-0.9-0.9-0.4-0.10.9-0.90.3-1.2-0.80.9-0.90.70.90.80.4
Pavlov. Cond. response bias0.10.20.60.5-0.30.40.8-0.10.3-0.3-0.3-0.70.7-0.20.2-0.8-0.60.1-0.10.1-0.3-0.10.20.5
Pavlov. Cond. lever latency0.60.92.01.1-1.31.41.4-1.20.9-0.9-0.9-1.0-1.21.0-0.9-0.2-1.2-0.70.7-0.70.00.10.0-0.4
Pavlov. Cond. magazine entry latency0.91.14.0-0.61.8-1.9-2.01.5-0.60.60.60.31.0-1.01.00.11.60.9-0.90.8-0.4-0.4-0.40.1
Pavlov. Cond. change in total contacts1.22.05.5-1.32.0-2.1-2.41.7-1.41.41.40.81.4-1.41.4-0.42.01.4-1.41.3-0.8-0.9-0.4-0.0
Pavlov. Cond. index score1.01.43.9-0.91.8-1.9-2.01.6-1.01.01.00.51.0-1.31.2-0.11.71.1-1.11.1-0.6-0.8-0.40.0
Pavlov. Cond. latency score1.21.54.4-1.01.9-2.0-2.11.6-1.11.11.10.51.1-1.31.3-0.11.81.2-1.21.1-0.6-0.7-0.50.0
Pavlov. Cond. lever contacts0.60.81.6-0.81.3-1.3-1.21.1-0.80.80.80.60.9-1.11.0-0.01.20.8-0.80.8-0.3-0.5-0.10.2
Pavlov. Cond. magazine entry number1.51.95.70.9-2.02.22.4-1.71.0-1.0-1.0-0.3-1.51.4-1.40.5-1.9-1.41.4-1.31.00.90.8-0.1
Pavlov. Cond. intertrial magazine entries0.40.52.2-1.30.5-0.30.00.8-1.01.01.01.51.10.2-0.20.90.0-0.30.2-0.40.50.50.50.7
Pavlov. Cond. lever-magazine prob. diff.0.81.13.8-0.71.7-1.8-2.01.4-0.70.70.70.40.9-1.11.1-0.01.61.0-1.00.9-0.4-0.5-0.30.2
Pavlov. Cond. response bias0.81.13.0-1.01.5-1.6-1.71.3-1.01.01.00.71.3-1.21.2-0.11.41.0-1.00.9-0.4-0.6-0.00.5
Time in closed arm before self-admin0.60.72.2-1.31.2-1.4-0.81.2-1.11.11.11.51.0-0.0-0.00.60.80.2-0.30.20.0-0.4-0.4-0.2
Time in closed arm after self-admin0.91.04.2-1.01.4-1.7-1.41.3-0.50.50.51.32.10.4-0.51.20.7-0.10.1-0.30.51.10.11.0
Time in open arm before self-admin0.70.82.41.1-1.31.30.8-1.40.9-0.9-0.9-1.0-1.50.6-0.6-0.0-0.9-0.70.7-0.60.30.30.6-0.2
Time in open arm after self-admin1.21.36.40.9-0.71.10.8-0.70.4-0.4-0.4-1.4-2.5-1.01.1-1.30.30.8-0.81.0-1.0-1.8-1.0-2.1
Bone: periosteal estimation3.67.622.1-4.73.3-3.3-3.83.2-3.53.53.54.72.6-1.11.02.62.50.4-0.50.21.00.62.31.6
Bone: periosteal perimeter1.83.012.1-2.61.3-1.5-1.81.2-1.31.31.33.51.00.4-0.53.00.6-1.00.9-1.11.91.33.01.7
Bone: post-yield work2.02.98.1-2.81.9-1.7-1.92.2-2.72.72.72.30.7-0.80.80.81.90.8-0.90.8-0.4-0.9-0.0-1.0
Progressive ratio test 1 active lever presses1.41.72.8-0.91.4-1.5-0.61.4-1.51.51.50.30.6-1.51.5-1.11.41.5-1.51.5-1.1-1.7-1.0-1.2
Progressive ratio test 1 breakpoint1.51.93.1-1.01.5-1.5-0.71.5-1.61.61.60.30.6-1.61.6-1.11.51.6-1.61.6-1.2-1.8-1.1-1.3
Progressive ratio test 1 inactive lever presses4.05.79.9-2.82.7-2.7-2.22.8-3.23.23.21.82.4-2.42.4-1.32.62.4-2.42.3-1.4-1.8-1.7-1.0
Progressive ratio test 2 active lever presses1.11.32.4-1.41.3-1.2-1.21.3-1.61.61.60.91.0-1.11.1-0.41.31.1-1.11.1-0.6-0.6-0.5-0.7
Progressive ratio test 2 breakpoint1.21.42.6-1.51.4-1.3-1.21.4-1.61.61.61.01.1-1.11.1-0.41.41.1-1.11.1-0.6-0.6-0.4-0.6
Progressive ratio test 2 inactive lever presses1.62.63.7-1.51.8-1.7-1.71.8-1.81.81.80.81.4-1.91.9-1.11.91.9-1.91.8-1.2-1.0-1.3-0.9
Incentive Sensitization - Responses0.10.21.0-0.70.3-0.1-0.40.3-0.50.50.50.71.00.2-0.20.40.1-0.10.1-0.20.40.50.50.5
Incentive Sensitization - Breakpoint0.20.21.1-0.80.2-0.1-0.40.3-0.40.40.40.71.00.3-0.30.5-0.0-0.20.3-0.40.50.60.60.7
Sum of active levers in priming session hrs 5-60.70.62.00.5-0.10.40.80.0-0.00.00.0-1.10.1-0.70.7-1.40.30.9-0.90.9-1.3-1.2-1.1-1.2
Progressive ratio0.60.93.40.0-0.10.3-0.9-0.10.8-0.8-0.80.9-0.40.9-0.91.9-0.0-1.11.0-1.01.61.01.40.6
Food seeking constrained by brief footshock2.02.44.01.1-1.31.00.7-1.51.8-1.8-1.80.2-0.42.0-2.01.6-1.7-2.02.0-2.01.90.51.71.4
Seeking ratio, punishment vs. effort0.10.20.70.5-0.4-0.00.9-0.50.4-0.4-0.4-0.50.30.3-0.3-0.4-0.8-0.20.3-0.3-0.0-0.20.00.3
Retroperitoneal fat weight1.46.015.5-0.21.4-1.3-0.41.5-1.51.51.5-1.6-1.0-3.03.1-3.02.23.0-3.03.2-3.1-3.5-3.2-3.9
Reaction time number correct0.51.02.2-0.10.8-0.5-0.50.9-0.80.80.8-0.70.8-1.51.5-1.31.01.3-1.31.3-1.2-0.9-1.2-0.4
Reaction time mean minus median0.10.20.6-0.60.6-0.70.00.7-0.50.50.50.30.4-0.50.50.30.20.2-0.20.20.0-0.20.50.3
Reaction time mean minus median AUC0.51.34.4-1.71.5-1.7-0.91.6-1.31.31.31.42.1-0.60.60.50.50.3-0.30.10.20.11.01.4
Reaction time num false alarms0.10.20.7-0.6-0.00.0-0.2-0.0-0.40.40.40.80.50.5-0.50.5-0.2-0.40.4-0.40.3-0.10.40.4
Reaction time num false alarms AUC0.20.30.7-0.1-0.50.50.2-0.50.1-0.1-0.10.5-0.10.9-0.90.7-0.5-0.70.7-0.70.50.20.40.4
Reaction time trials correct on left0.51.02.2-0.10.8-0.5-0.50.9-0.80.80.8-0.70.8-1.51.5-1.31.01.3-1.31.3-1.2-0.9-1.2-0.4
Reaction time trials on left0.61.02.3-0.10.9-0.6-0.50.9-0.80.80.8-0.70.8-1.51.5-1.31.01.4-1.31.3-1.2-1.0-1.1-0.3
Reaction time mean0.50.82.0-1.41.2-1.3-0.41.4-1.21.21.21.00.8-0.80.80.10.90.7-0.70.6-0.5-0.90.2-0.0
Reaction time mean AUC0.91.53.1-1.71.6-1.6-0.91.8-1.61.61.61.31.2-1.11.1-0.11.31.0-1.01.0-0.6-1.0-0.1-0.3
Median of all reaction times0.81.12.6-1.61.4-1.4-0.81.5-1.41.41.41.41.0-0.80.80.11.00.7-0.80.7-0.4-0.90.20.0
Reaction time omissions0.30.41.6-0.40.9-0.9-0.60.9-0.50.50.50.11.3-0.40.40.40.30.2-0.20.0-0.1-0.71.11.2
Reaction time false alarm rate0.81.12.60.2-1.00.90.7-1.10.7-0.7-0.70.7-0.61.6-1.61.3-1.1-1.41.4-1.41.10.61.10.6
Reaction time premature initiation rate2.63.511.32.3-2.52.73.4-2.12.0-2.0-2.0-2.1-2.71.6-1.6-0.3-1.8-1.11.1-0.90.60.5-0.9-1.6
Reaction time premature initiations0.81.45.21.6-1.41.72.3-1.00.9-0.9-0.9-1.9-1.70.4-0.4-0.9-0.7-0.10.10.1-0.2-0.1-1.5-1.7
Std. dev. reaction times0.10.10.3-0.40.5-0.50.20.6-0.50.50.50.10.3-0.50.50.10.20.2-0.20.2-0.2-0.40.40.3
Reaction time trials completed0.61.02.3-0.10.9-0.6-0.50.9-0.80.80.8-0.70.8-1.51.5-1.31.01.4-1.31.3-1.2-1.0-1.1-0.3
Reaction time trials AUC0.61.22.5-0.21.0-0.7-0.71.1-0.90.90.9-0.70.9-1.61.6-1.31.11.4-1.41.4-1.3-1.0-1.1-0.4
Run reversals in cocaine runway, females0.20.20.50.6-0.60.40.3-0.70.5-0.5-0.5-0.6-0.20.2-0.2-0.4-0.4-0.10.1-0.1-0.50.3-0.20.2
Run reversals in cocaine runway, males0.20.20.9-0.2-0.10.00.2-0.20.1-0.1-0.10.6-0.30.3-0.30.4-0.0-0.20.2-0.10.60.9-0.1-1.0
Latency to leave start box in cocaine runway0.50.54.1-0.20.7-0.5-0.10.9-0.50.50.5-0.22.0-0.60.6-1.10.20.8-0.80.6-0.8-0.5-0.50.4
Latency to leave start box in cocaine runway, F1.31.55.20.10.7-0.60.30.8-0.70.70.7-1.01.4-1.31.4-2.30.51.6-1.51.4-2.0-1.8-1.2-0.4
Latency to leave start box in cocaine runway, M1.21.15.6-1.20.9-0.8-1.01.1-0.50.50.51.72.40.6-0.61.20.2-0.40.4-0.61.11.70.71.2
Std. dev. time between licks in bursts2.12.96.4-0.71.8-1.9-2.21.5-1.11.11.1-0.2-0.2-1.91.9-1.32.21.9-2.02.0-1.6-2.5-1.8-2.3
Total sessions with >9 infusions1.01.23.6-1.91.0-0.9-0.71.1-1.71.71.71.71.8-0.80.8-0.20.80.7-0.70.6-0.2-0.8-0.40.4
Short access day 1 total inactive lever presses3.24.26.7-2.62.5-2.4-2.52.5-2.62.62.62.02.0-1.91.9-0.52.41.9-1.91.7-0.9-1.5-0.8-0.8
Short access day 10 total inactive lever presses0.51.22.3-0.70.9-0.7-1.30.9-1.11.11.10.3-0.0-1.31.3-0.81.51.3-1.41.4-1.0-0.7-1.4-1.4
Short access day 1 total infusions2.02.78.1-2.61.8-1.6-2.01.8-2.22.22.22.42.8-1.11.10.01.41.0-1.00.8-0.1-0.60.00.9
Short access day 10 total infusions3.74.811.9-3.42.7-2.8-2.12.8-3.03.03.03.23.0-1.31.20.12.21.5-1.51.3-0.5-1.2-0.7-0.3
Short access total infusions4.05.112.4-3.52.7-2.6-2.72.8-3.13.13.13.12.9-1.71.60.12.31.6-1.61.4-0.4-1.1-0.50.1
Short access day 1 locomotion1.21.53.5-1.91.4-1.4-0.91.5-1.71.71.71.51.5-1.01.0-0.21.00.9-0.90.8-0.4-0.9-0.2-0.3
Short access day 10 total locomotion0.40.84.8-1.70.6-1.0-0.40.7-1.01.01.02.20.50.1-0.11.10.5-0.20.2-0.20.80.50.50.1
Short access total locomotion0.91.13.7-1.91.1-1.2-0.61.2-1.51.51.51.91.4-0.60.60.20.70.5-0.50.4-0.0-0.50.10.1
One hour access (0.3 mA shock)1.11.33.2-1.81.3-1.4-1.21.3-1.71.71.71.31.2-0.80.8-0.21.10.9-0.90.8-0.5-0.2-0.2-0.2
Compulsive drug intake0.80.92.3-0.61.1-1.1-1.50.9-0.80.80.80.20.2-1.01.0-0.51.41.1-1.11.1-1.0-1.1-1.0-0.9
One hour access (shock baseline)0.20.31.2-0.90.4-0.4-0.30.5-0.60.60.61.10.60.1-0.10.60.1-0.20.2-0.20.60.70.60.3
Social response proportion0.30.31.2-0.60.3-0.20.20.5-0.60.60.60.60.80.3-0.30.3-0.5-0.30.4-0.50.20.21.10.8
Social responses1.51.93.8-1.21.4-1.3-0.41.6-1.81.81.80.22.0-1.31.3-1.60.61.4-1.41.2-1.7-1.8-0.60.1
Social time1.01.43.6-1.71.3-1.3-0.61.5-1.71.71.71.91.6-0.80.8-0.20.80.8-0.80.7-0.8-1.0-0.30.1
Soleus weight0.61.74.8-1.40.1-0.5-0.50.1-0.40.40.42.10.71.7-1.82.2-0.4-1.41.4-1.61.71.52.10.7
Bone: stiffness2.94.611.3-3.02.9-2.7-3.42.9-2.82.82.82.32.7-1.61.60.22.31.4-1.51.2-0.7-0.60.00.6
Tibialis anterior weight0.20.62.2-1.10.1-0.3-0.50.1-0.50.50.51.50.91.0-1.00.9-0.4-0.70.7-0.80.90.91.00.5
Time to tail flick, vehicle, before self-admin0.20.21.50.20.3-0.4-0.60.1-0.00.00.0-0.5-1.1-0.50.5-0.00.70.4-0.40.5-0.2-0.3-0.3-1.2
Time to tail flick, vehicle, after self-admin1.82.44.70.4-1.41.41.4-1.41.0-1.0-1.00.5-0.02.2-2.21.7-1.9-2.02.0-2.11.81.32.01.5
Time to tail flick, test, before self-admin2.72.86.72.3-1.91.91.3-2.02.4-2.4-2.4-1.6-2.61.2-1.21.0-1.2-1.41.4-1.21.50.6-0.1-0.2
Time to tail flick, test, after self-admin3.33.56.42.4-2.42.31.6-2.52.5-2.5-2.5-1.6-2.31.5-1.50.6-1.9-1.71.7-1.51.21.20.70.8
Delta time to tail flick, vehicle, before/after SA1.00.92.50.5-1.10.91.5-1.00.5-0.5-0.5-0.10.41.3-1.30.4-1.6-1.11.2-1.20.70.61.01.2
Delta time to tail flick, test, before/after SA0.10.10.40.4-0.50.6-0.1-0.60.2-0.2-0.2-0.5-0.00.1-0.1-0.5-0.5-0.10.1-0.1-0.50.20.60.5
Tibia length0.82.112.6-0.2-0.60.40.4-0.70.4-0.4-0.41.11.60.9-0.91.1-1.6-1.41.5-1.61.82.12.43.6
Ambulatory time before self-admin0.50.71.91.1-1.21.31.4-1.00.9-0.9-0.9-0.90.00.8-0.7-0.5-1.4-0.60.6-0.7-0.10.40.40.7
Ambulatory time after self-admin0.00.00.20.20.1-0.10.10.30.3-0.3-0.3-0.10.00.3-0.30.10.0-0.00.0-0.0-0.1-0.2-0.1-0.4
Bone: tissue strength3.94.05.9-1.61.9-1.8-1.62.0-2.32.32.30.52.0-2.42.4-2.31.82.4-2.42.3-2.2-1.8-1.5-0.9
Total heroin consumption1.01.23.01.4-0.60.40.3-0.81.7-1.7-1.7-0.8-0.31.2-1.20.8-1.0-1.11.1-1.11.10.21.40.6
Bone: trabecular number0.10.22.20.2-0.10.1-0.1-0.10.2-0.2-0.2-0.00.60.0-0.10.2-0.5-0.40.4-0.50.50.60.51.5
Bone: trabecular spacing0.10.10.4-0.30.3-0.3-0.10.2-0.30.30.30.20.3-0.20.2-0.40.40.4-0.40.4-0.5-0.5-0.6-0.5
Bone: trabecular thickness0.20.20.70.5-0.50.40.1-0.50.4-0.4-0.4-0.4-0.80.2-0.20.5-0.3-0.50.5-0.40.70.80.50.2
Bone: trabecular tissue density0.30.53.30.7-0.81.01.0-0.60.6-0.6-0.6-0.7-1.80.3-0.30.3-0.3-0.40.3-0.20.1-0.00.0-1.1
Water consumed over 24 hours0.50.73.70.7-0.90.91.1-0.90.7-0.7-0.7-0.3-1.90.3-0.30.6-0.5-0.60.6-0.40.51.30.3-0.7
Number of responses in last shaping day1.61.84.7-2.21.7-1.9-1.41.9-2.02.02.02.01.1-0.70.60.91.30.5-0.50.40.5-0.20.3-0.2