Hub : Genes

LOC102549596

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	NAcc	gene expression	LOC102549596	0.05	0.03	1.5e-06	0.05	0.04	0.04	0.04	1.4e-06	1.5e-05	3.0e-05	1.1e-05
2	PL	gene expression	LOC102549596	0.06	0.03	4.2e-07	0.03	0.06	0.04	0.04	2.3e-04	6.1e-07	2.4e-05	6.3e-05
3	BLA	gene expression	LOC102549596	0.06	0.04	1.2e-03	0.04	0.04	0.02	0.02	4.8e-03	2.3e-03	1.9e-02	1.9e-02
4	Brain	isoform ratio	XR_357971.4	0.18	0.08	1.1e-06	0.08	0.06	0.09	0.08	9.5e-08	1.5e-06	2.9e-08	4.6e-08
5	NAcc	intron excision ratio	chr10_98049905_98057892	0.05	0.03	8.1e-03	0.03	0.02	0.01	0.03	2.6e-04	5.1e-03	7.8e-03	5.8e-04
6	Brain	alternative polyA	XR_005490525.1	0.22	0.09	1.2e-10	0.12	0.11	0.1	0.11	4.2e-11	1.1e-10	7.9e-10	2.8e-10
7	Brain	alternative polyA	XR_005490526.1	0.22	0.09	9.1e-11	0.12	0.12	0.1	0.11	3.3e-11	8.9e-11	7.0e-10	2.1e-10
8	Brain	isoform ratio	XR_005490526.1	0.19	0.09	8.3e-08	0.08	0.08	0.06	0.07	5.9e-08	1.0e-07	1.6e-06	4.5e-07
9	PL	intron excision ratio	chr10_98049905_98057892	0.04	0.03	6.5e-03	0.01	0.01	0	0	1.0e-02	7.1e-02	2.6e-01	1.1e-01
10	Brain	gene expression	LOC102549596	0.07	0.04	5.7e-08	0.06	0.08	0.06	0.06	1.4e-06	1.6e-07	1.5e-06	3.7e-06
11	NAcc	isoform ratio	XR_357971.4	0.03	0.02	8.7e-03	0.05	0.01	0.03	0.04	3.1e-06	9.6e-03	9.7e-05	1.3e-05
12	NAcc	alternative polyA	XR_005490525.1	0.02	0.01	5.3e-03	0.02	0.01	0.01	0.01	4.8e-03	1.4e-02	1.4e-02	3.9e-02
13	NAcc	alternative polyA	XR_005490526.1	0.02	0.01	3.6e-03	0.02	0.01	0.01	0.01	2.0e-03	6.7e-03	8.4e-03	2.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13
Bone: apparent density	0.0	0.0	0.1	-0.1	0.3	0.1	-0.2	-0.3	-0.3	0.3	0.3	-0.2	0.3	-0.1	-0.1	0.1
Area under the delay curve	0.9	0.9	2.9	-1.4	0.9	0.8	0.7	0.7	0.8	-0.8	-0.8	0.8	1.7	0.6	-0.8	0.8
BMI with tail	0.9	2.8	9.5	2.7	-2.7	-2.0	0.7	0.9	0.9	-0.9	-0.9	0.5	-3.1	0.9	1.3	-1.3
BMI without tail	0.6	1.1	2.6	1.1	-1.6	-1.2	1.2	0.9	0.9	-0.9	-0.9	1.5	-1.2	0.9	0.4	-0.4
Body weight	1.3	5.2	8.0	2.7	-2.4	-2.8	2.3	2.5	2.5	-2.5	-2.5	2.1	-2.1	2.5	1.1	-1.1
Weight adjusted by age	0.4	0.5	2.6	1.6	-1.3	-1.2	-0.0	0.0	0.1	-0.1	-0.1	-0.1	-0.6	0.0	0.2	-0.2
Bone surface	2.1	3.7	6.8	-1.6	2.5	1.3	-1.9	-2.0	-2.0	2.0	2.0	-1.9	2.6	-1.8	-1.4	1.4
Bone volume	1.6	2.8	5.6	-1.8	2.2	1.3	-1.5	-1.6	-1.6	1.6	1.6	-1.5	2.4	-1.5	-1.4	1.4
Breakpoint value in progressive ratio session	1.3	1.4	3.4	-0.0	-0.3	-0.1	1.8	1.5	1.6	-1.6	-1.6	1.9	0.0	1.5	0.0	-0.0
Number of licking bursts	2.7	3.2	7.2	-2.6	2.7	2.6	-0.9	-0.8	-0.8	0.8	0.8	-0.9	2.6	-0.7	-2.1	2.1
Context. condit. distance diff. score	0.5	0.7	1.6	0.9	-1.1	-0.9	0.2	0.4	0.4	-0.4	-0.4	-0.1	-1.3	0.4	1.3	-1.3
Locomotion velocity, session 1	0.5	0.6	1.2	-0.4	0.2	-0.1	1.1	0.9	0.9	-0.9	-0.9	1.1	0.6	0.9	-0.3	0.3
Locomotion distance, session 1	2.4	3.1	4.5	1.8	-2.1	-2.0	1.5	1.7	1.7	-1.7	-1.7	1.2	-1.7	1.7	2.0	-2.0
Locomotion velocity, session 2	0.4	0.5	1.0	0.9	-0.6	-0.7	0.7	0.5	0.5	-0.5	-0.5	1.0	-0.8	0.5	0.9	-0.9
Locomotion distance, session 2	2.7	3.8	6.5	2.5	-2.2	-2.3	1.6	1.5	1.5	-1.5	-1.5	1.7	-2.1	1.5	2.5	-2.5
Locomotion velocity, session 3	1.1	1.3	1.9	0.9	-1.3	-1.4	1.2	1.1	1.1	-1.1	-1.1	1.2	-0.9	1.1	1.1	-1.1
Locomotion distance, session 3	1.6	1.7	4.9	1.9	-1.4	-1.3	0.5	0.3	0.3	-0.3	-0.3	0.8	-1.9	0.3	2.2	-2.2
Stereotopy head waving bouts, day 3	0.1	0.1	0.7	-0.6	0.0	0.4	0.0	0.1	0.1	-0.1	-0.1	-0.1	0.1	0.1	-0.8	0.8
Stereotopy head waving duration, day 3	0.6	0.7	1.5	-0.9	0.6	0.9	-0.9	-0.7	-0.7	0.7	0.7	-1.2	0.4	-0.8	-1.1	1.1
Locomotion velocity, session 7	1.2	1.3	3.8	1.6	-1.2	-1.3	0.0	0.1	0.1	-0.1	-0.1	-0.1	-1.7	0.0	2.0	-2.0
Locomotion distance, session 7	4.8	6.0	19.2	3.6	-2.8	-2.5	0.5	0.4	0.4	-0.4	-0.4	0.6	-3.5	0.4	4.4	-4.4
Stereotopy head waving bouts, day 7	0.5	0.5	1.8	-1.0	0.9	0.5	-0.2	-0.3	-0.3	0.3	0.3	-0.2	1.0	-0.2	-1.3	1.3
Stereotopy head waving duration, day 7	2.4	2.9	6.5	-2.1	2.1	1.8	-1.0	-1.2	-1.2	1.2	1.2	-0.9	1.9	-1.1	-2.5	2.5
Locomotion velocity, session 8	0.0	0.0	0.3	0.1	-0.1	0.1	0.1	0.1	0.1	-0.1	-0.1	0.1	-0.6	0.1	0.1	-0.1
Locomotion distance, session 8	2.5	3.6	8.6	2.7	-2.5	-2.4	0.8	0.8	0.8	-0.8	-0.8	0.7	-2.7	0.7	2.9	-2.9
Degree of sensitization distance	0.8	0.8	2.5	1.3	-1.1	-1.0	-0.2	-0.1	-0.1	0.1	0.1	-0.4	-1.1	-0.1	1.6	-1.6
Degree of sensitization stereotypy	0.4	0.4	1.4	-0.8	0.9	0.5	-0.1	-0.3	-0.3	0.3	0.3	0.0	1.0	-0.2	-1.2	1.2
Conditioned locomotion	0.4	0.5	1.8	-0.3	0.2	0.4	-1.1	-0.8	-0.8	0.8	0.8	-1.3	-0.0	-0.8	-0.2	0.2
Cocaine response after cond. corrected	0.2	0.2	0.4	-0.1	0.4	0.6	0.4	0.6	0.6	-0.6	-0.6	0.1	0.2	0.6	-0.5	0.5
Cocaine response after cond. not corrected	0.6	0.6	1.4	0.4	-0.1	-0.1	0.9	1.2	1.2	-1.2	-1.2	0.6	-0.1	1.2	-0.0	0.0
Cocaine response before conditioning	0.9	1.1	2.9	1.2	-1.2	-1.7	0.6	0.7	0.7	-0.7	-0.7	0.6	-1.0	0.8	1.4	-1.4
Saline control response	0.4	0.5	2.2	1.1	-0.7	-1.5	0.0	0.3	0.3	-0.3	-0.3	-0.2	-0.2	0.3	1.0	-1.0
Bone: connectivity density	0.3	0.5	1.0	0.1	0.5	0.2	-0.9	-1.0	-1.0	1.0	1.0	-0.8	0.3	-0.9	0.1	-0.1
Bone: cortical apparent density	2.6	3.5	5.1	1.1	-1.9	-1.2	2.2	2.2	2.2	-2.2	-2.2	2.1	-1.4	2.1	1.3	-1.3
Bone: cortical area	0.8	1.2	3.2	1.8	-0.9	-1.8	-1.0	-0.7	-0.7	0.7	0.7	-1.4	-1.3	-0.5	0.8	-0.8
Bone: cortical porosity	1.3	1.4	2.6	-1.6	1.2	0.6	-1.1	-1.0	-1.0	1.0	1.0	-1.1	1.4	-1.0	-1.5	1.5
Bone: cortical porosity	1.5	1.6	2.7	-1.7	1.3	0.8	-1.2	-1.2	-1.2	1.2	1.2	-1.2	1.4	-1.1	-1.4	1.4
Bone: cortical thickness	7.2	11.8	24.3	4.1	-4.4	-4.9	2.7	3.1	3.1	-3.1	-3.1	2.2	-3.9	3.3	2.8	-2.8
Bone: cortical thickness	1.9	2.2	4.6	1.9	-1.8	-2.1	1.2	1.1	1.1	-1.1	-1.1	1.2	-1.7	1.2	1.5	-1.5
Bone: cortical tissue density	2.4	3.2	4.9	0.9	-1.7	-1.0	2.2	2.2	2.2	-2.2	-2.2	2.1	-1.2	2.1	1.1	-1.1
Condit. Reinf. active minus inactive responses	1.1	1.2	2.9	1.7	-1.4	-1.0	-0.7	-0.8	-0.7	0.7	0.7	-0.6	-1.6	-0.8	1.3	-1.3
Condit. Reinf. active-inactive response ratio	1.5	1.6	2.3	1.3	-1.0	-0.4	-1.3	-1.5	-1.4	1.4	1.4	-1.1	-1.5	-1.5	1.1	-1.1
Condit. Reinf. active responses	1.1	1.3	3.7	1.9	-1.8	-1.5	0.1	0.1	0.1	-0.1	-0.1	0.2	-1.8	0.0	1.6	-1.6
Condit. Reinf. inactive responses	1.5	1.8	2.5	1.0	-1.2	-1.4	1.6	1.6	1.6	-1.6	-1.6	1.6	-0.6	1.5	1.0	-1.0
Incentive salience index mean	0.6	0.7	1.9	1.4	-1.3	-0.9	-0.2	-0.3	-0.2	0.2	0.2	-0.2	-1.3	-0.3	1.1	-1.1
Condit. Reinf. lever presses	0.9	1.3	2.6	1.5	-1.6	-1.4	0.7	0.8	0.8	-0.8	-0.8	0.6	-1.2	0.6	1.5	-1.5
Condit. Reinf. active minus inactive responses	0.3	0.4	0.6	-0.1	0.7	0.1	-0.7	-0.8	-0.8	0.8	0.8	-0.7	0.2	-0.8	-0.3	0.3
Condit. Reinf. active-inactive response ratio	0.2	0.2	0.6	-0.3	0.5	0.3	-0.6	-0.6	-0.6	0.6	0.6	-0.8	0.3	-0.6	-0.1	0.1
Condit. Reinf. active responses	0.2	0.2	0.8	0.9	-0.2	-0.7	-0.2	-0.3	-0.3	0.3	0.3	-0.2	-0.6	-0.3	0.6	-0.6
Condit. Reinf. inactive responses	0.7	0.9	2.6	1.6	-1.1	-1.6	0.3	0.2	0.2	-0.2	-0.2	0.4	-1.2	0.3	1.2	-1.2
Condit. Reinf. lever presses	0.6	0.9	1.4	1.2	-0.4	-0.7	-0.8	-1.0	-1.0	1.0	1.0	-0.8	-0.9	-0.9	1.0	-1.0
Condit. Reinf. lever reinforcers received	0.3	0.5	1.4	1.2	-0.4	-0.9	-0.4	-0.5	-0.5	0.5	0.5	-0.4	-0.8	-0.4	0.9	-0.9
Conditioned reinforcement - actives	0.1	0.1	0.4	-0.3	0.6	0.5	-0.2	-0.2	-0.2	0.2	0.2	-0.2	0.2	-0.3	-0.6	0.6
Conditioned reinforcement - inactives	1.8	2.0	2.9	1.6	-1.0	-0.8	-1.5	-1.7	-1.5	1.5	1.5	-1.4	-1.7	-1.7	1.2	-1.2
Conditioned locomotion	0.2	0.2	0.5	-0.0	0.3	0.2	-0.4	-0.5	-0.3	0.3	0.3	-0.3	0.3	-0.5	-0.7	0.7
Patch foraging indifference point 0 sec	1.6	2.5	8.2	2.9	-2.2	-2.3	0.8	0.5	0.4	-0.4	-0.4	0.9	-2.3	0.4	1.9	-1.9
Patch foraging indifference point AUC	0.5	0.6	1.5	0.2	0.0	0.5	-1.1	-0.9	-1.0	1.0	1.0	-1.2	-0.2	-1.0	0.1	-0.1
Delay disc. indifference point, 0s delay	0.2	0.2	0.6	0.3	-0.1	-0.3	0.6	0.5	0.6	-0.6	-0.6	0.8	0.2	0.5	0.1	-0.1
Delay disc. indifference point, 16s delay	0.2	0.2	0.9	-0.7	0.5	0.4	0.2	0.0	0.0	-0.0	-0.0	0.4	0.9	0.0	-0.3	0.3
Delay disc. indifference point, 2s delay	1.7	1.9	5.4	-1.8	1.0	0.9	1.2	1.2	1.2	-1.2	-1.2	1.2	2.3	1.1	-1.5	1.5
Delay disc. indifference point, 24s delay	0.3	0.3	1.2	-0.8	0.7	0.4	0.1	0.2	0.3	-0.3	-0.3	0.0	1.1	0.3	-0.6	0.6
Delay disc. indifference point, 4s delay	1.1	1.2	3.3	-1.8	1.3	1.4	0.3	0.3	0.4	-0.4	-0.4	0.4	1.8	0.2	-1.4	1.4
Delay disc. indifference point, 8s delay	0.4	0.4	1.6	-1.2	0.6	0.7	0.4	0.4	0.6	-0.6	-0.6	0.4	1.3	0.4	-0.3	0.3
Indifference point function ln k	0.9	1.2	2.8	1.4	-1.4	-1.7	0.7	0.9	0.9	-0.9	-0.9	0.5	-1.3	0.9	1.2	-1.2
Indifference point function log k	0.9	1.2	2.8	1.4	-1.4	-1.7	0.7	0.9	0.9	-0.9	-0.9	0.5	-1.3	0.9	1.2	-1.2
Patch foraging total patch changes 0 sec	1.7	2.8	8.8	3.0	-2.2	-2.4	0.8	0.5	0.5	-0.5	-0.5	0.9	-2.3	0.5	2.0	-2.0
Patch foraging total patch changes 12 sec	1.1	1.4	5.6	2.4	-1.4	-1.6	-0.0	-0.1	-0.2	0.2	0.2	0.1	-1.8	-0.2	1.5	-1.5
Patch foraging total patch changes 18 sec	1.0	1.3	3.9	2.0	-1.4	-1.4	0.7	0.5	0.4	-0.4	-0.4	0.8	-1.6	0.5	1.4	-1.4
Patch foraging total patch changes 24 sec	1.1	1.3	3.2	1.8	-0.7	-0.9	-0.9	-1.2	-1.2	1.2	1.2	-0.5	-1.4	-1.2	1.1	-1.1
Patch foraging total patch changes 6 sec	1.6	2.4	8.3	2.9	-2.4	-2.1	0.1	-0.1	-0.1	0.1	0.1	0.1	-2.4	-0.1	1.8	-1.8
Patch foraging time to switch 0 sec	0.4	0.6	1.3	-1.2	1.0	0.8	0.6	0.4	0.4	-0.4	-0.4	1.0	1.1	0.4	-0.9	0.9
Patch foraging water rate 0 sec	0.4	0.6	1.8	1.3	-1.0	-0.9	-0.4	-0.3	-0.3	0.3	0.3	-0.6	-1.0	-0.3	1.1	-1.1
Patch foraging water rate 12 sec	0.3	0.5	0.7	0.8	-0.7	-0.8	0.9	0.6	0.6	-0.6	-0.6	0.7	-0.5	0.6	0.5	-0.5
Patch foraging water rate 18 sec	0.6	0.8	1.0	1.0	-0.6	-0.4	-0.9	-1.0	-1.0	1.0	1.0	-0.8	-0.9	-1.0	0.9	-0.9
Patch foraging water rate 24 sec	2.3	3.1	7.8	2.7	-2.3	-2.2	0.0	0.1	0.1	-0.1	-0.1	-0.1	-2.7	0.2	2.8	-2.8
Patch foraging water rate 6 sec	2.0	2.9	4.3	1.4	-1.4	-1.7	2.0	2.1	2.1	-2.1	-2.1	1.7	-1.1	2.0	1.0	-1.0
Seeking ratio, delayed vs. immediate footshock	1.0	1.1	1.7	-0.7	0.8	0.6	-1.2	-1.3	-1.1	1.1	1.1	-1.3	0.9	-1.3	-1.0	1.0
Distance traveled before self-admin	0.4	0.4	1.3	-0.8	0.8	0.8	0.2	0.2	0.3	-0.3	-0.3	0.1	0.6	0.2	-1.1	1.1
Distance traveled after self-admin	0.4	0.5	0.9	-0.5	0.4	0.8	-0.8	-1.0	-0.9	0.9	0.9	-0.6	0.2	-0.9	-0.3	0.3
Extensor digitorum longus weight	0.3	1.2	2.3	1.2	-1.1	-0.7	1.0	1.2	1.2	-1.2	-1.2	0.8	-1.5	1.2	0.8	-0.8
Bone: elastic displacement	2.8	3.2	5.8	1.7	-2.0	-2.4	1.7	1.9	1.9	-1.9	-1.9	1.3	-1.5	2.1	1.1	-1.1
Bone: elastic work	1.9	2.4	7.6	2.2	-2.3	-2.8	0.6	0.8	0.8	-0.8	-0.8	0.3	-2.1	0.9	1.7	-1.7
Bone: endosteal estimation	10.2	22.2	35.1	-2.4	4.2	3.8	-5.8	-5.9	-5.9	5.9	5.9	-5.4	2.7	-5.8	-1.9	1.9
Bone: endosteal perimeter	10.0	20.7	27.6	-3.3	4.7	4.1	-5.3	-5.3	-5.3	5.3	5.3	-5.0	3.7	-5.1	-2.9	2.9
Epididymis fat weight	2.4	5.5	9.5	3.1	-3.0	-3.1	2.2	2.0	1.9	-1.9	-1.9	2.3	-2.2	2.0	2.3	-2.3
Delta time in closed arm before/after self-admin	0.9	0.9	1.8	0.1	0.3	0.4	-1.2	-1.2	-1.2	1.2	1.2	-1.4	-0.5	-1.2	0.4	-0.4
Delta time in open arm before/after self-admin	2.8	2.7	4.5	0.6	-1.4	-1.7	2.0	2.1	2.1	-2.1	-2.1	1.8	-0.2	2.1	0.4	-0.4
Diff in mean of infusions in LGA sessions	0.1	0.1	0.4	-0.0	-0.2	0.3	0.6	0.2	0.2	-0.2	-0.2	0.6	-0.2	0.1	0.1	-0.1
Delay discount exponential model param	1.1	1.2	3.8	1.7	-1.1	-1.0	-0.7	-0.7	-0.8	0.8	0.8	-0.7	-1.9	-0.7	1.0	-1.0
Extinction: sum of active levers before priming	1.0	1.0	2.2	1.1	-1.0	-1.1	1.1	0.7	0.7	-0.7	-0.7	1.5	-1.3	0.7	0.8	-0.8
Active lever presses in extinction session 6	0.1	0.1	0.5	-0.4	0.3	0.4	-0.0	-0.0	-0.0	0.0	0.0	0.1	0.7	-0.1	-0.7	0.7
Bone: final force	1.4	2.2	3.3	1.8	-0.9	-1.6	-1.7	-1.5	-1.5	1.5	1.5	-1.8	-1.7	-1.3	1.2	-1.2
Bone: final moment	1.2	1.9	4.2	2.1	-1.3	-2.0	-1.2	-1.0	-1.0	1.0	1.0	-1.3	-1.9	-0.8	1.3	-1.3
Food consumed during 24 hour testing period	0.2	0.2	0.9	-0.5	0.8	0.4	-0.4	-0.2	-0.2	0.2	0.2	-0.5	0.9	-0.2	-0.2	0.2
Glucose	0.0	0.0	0.2	0.3	-0.0	0.0	-0.1	-0.0	-0.1	0.1	0.1	-0.2	-0.3	-0.0	0.4	-0.4
Heart weight	1.4	2.0	6.3	2.5	-1.7	-2.1	-0.5	-0.2	-0.3	0.3	0.3	-0.5	-1.8	-0.1	2.0	-2.0
Delay discount hyperbolic model param	1.1	1.2	3.8	1.7	-1.1	-1.0	-0.8	-0.8	-0.8	0.8	0.8	-0.8	-1.9	-0.7	1.0	-1.0
Intermittent access intake day 1-15 change	0.7	0.7	1.0	-0.7	0.2	0.3	0.9	0.9	1.0	-1.0	-1.0	0.9	0.6	0.9	-0.7	0.7
Intermittent access intake escalation	0.4	0.4	0.8	-0.1	-0.5	-0.3	0.8	0.8	0.9	-0.9	-0.9	0.7	0.0	0.8	0.0	-0.0
Intermittent access intake escalation 2	1.3	1.3	2.3	-0.6	-0.1	0.1	1.5	1.5	1.5	-1.5	-1.5	1.4	0.7	1.5	-0.6	0.6
Intermitt. access day 1 inactive lever presses	4.0	4.3	11.7	3.4	-3.0	-2.9	0.2	0.3	0.3	-0.3	-0.3	0.1	-3.4	0.3	2.8	-2.8
Intermitt. access day 15 inactive lever presses	0.2	0.2	0.4	0.4	-0.5	-0.6	-0.2	-0.5	-0.4	0.4	0.4	-0.1	-0.4	-0.4	0.5	-0.5
Intermitt. access escalation Index	0.3	0.2	0.4	-0.2	0.3	0.4	-0.6	-0.7	-0.6	0.6	0.6	-0.7	-0.1	-0.6	0.0	-0.0
Intermittent access day 1 total infusions	0.6	0.7	1.3	0.6	-0.5	-0.5	-1.0	-1.0	-0.9	0.9	0.9	-1.1	-0.7	-1.0	0.6	-0.6
Intermittent access day 15 total infusions	0.4	0.5	1.2	0.1	-0.2	-0.1	-1.0	-0.9	-0.8	0.8	0.8	-1.1	-0.2	-0.9	0.1	-0.1
Intermittent access terminal intake (last 3 days)	0.5	0.6	1.3	-0.4	0.4	0.4	-1.0	-0.9	-0.8	0.8	0.8	-1.2	0.3	-0.9	-0.5	0.5
Intermittent access total infusions	0.9	1.0	2.1	0.6	-0.5	-0.4	-1.3	-1.2	-1.1	1.1	1.1	-1.4	-0.8	-1.2	0.7	-0.7
Intermittent access day 1 locomotion	0.5	0.6	1.5	1.1	-1.1	-1.2	-0.3	-0.3	-0.2	0.2	0.2	-0.4	-1.0	-0.3	1.0	-1.0
Intermittent access day 15 total locomotion	0.6	0.6	2.4	1.3	-1.4	-1.5	0.2	0.2	0.3	-0.3	-0.3	0.1	-1.1	0.1	0.6	-0.6
Intermittent access total locomotion	0.5	0.5	1.6	1.0	-1.1	-1.3	-0.5	-0.5	-0.3	0.3	0.3	-0.5	-0.9	-0.5	0.7	-0.7
Intermittent access standard deviation	0.2	0.2	0.8	-0.2	0.1	0.3	-0.7	-0.5	-0.4	0.4	0.4	-0.9	0.1	-0.6	-0.2	0.2
Left kidney weight	0.3	1.0	2.1	-0.5	1.0	0.8	-1.0	-0.7	-0.8	0.8	0.8	-1.2	1.0	-0.7	-1.5	1.5
Right kidney weight	0.1	0.3	1.0	-0.2	0.7	0.3	-0.5	-0.2	-0.3	0.3	0.3	-0.7	0.8	-0.1	-1.0	1.0
Cocaine induced anxiety	0.3	0.4	1.2	0.9	-0.7	-0.7	0.1	0.0	0.1	-0.1	-0.1	0.0	-0.9	-0.0	1.1	-1.1
Post-drug Anxiety	0.2	0.2	0.7	0.5	-0.4	-0.5	-0.1	-0.3	-0.1	0.1	0.1	-0.2	-0.6	-0.2	0.9	-0.9
Baseline Anxiety	0.4	0.4	1.1	-1.0	0.8	0.6	0.3	0.2	0.2	-0.2	-0.2	0.3	0.9	0.3	-0.9	0.9
Tail length	0.6	1.9	6.0	-0.2	-0.3	-0.9	2.0	1.6	1.6	-1.6	-1.6	2.4	1.0	1.6	0.1	-0.1
Length with tail	1.0	3.7	6.6	0.9	-0.6	-1.7	2.5	2.5	2.4	-2.4	-2.4	2.6	0.5	2.6	0.4	-0.4
Length without tail	0.9	2.1	3.6	1.5	-0.7	-1.5	1.4	1.8	1.7	-1.7	-1.7	0.9	-0.7	1.9	1.1	-1.1
Times rat made contact with spout	1.2	1.4	2.5	-1.5	0.5	0.4	1.3	1.3	1.3	-1.3	-1.3	1.4	1.6	1.3	-0.5	0.5
Lifetime Intake	1.2	1.3	2.9	0.6	-0.4	-0.2	-1.6	-1.5	-1.4	1.4	1.4	-1.7	-0.8	-1.5	0.6	-0.6
Liver weight, left	0.0	0.1	0.3	0.0	0.6	0.1	-0.2	-0.2	-0.2	0.2	0.2	-0.1	0.3	-0.2	-0.0	0.0
Liver weight, right	0.1	0.2	0.6	0.5	-0.3	-0.4	-0.3	-0.4	-0.3	0.3	0.3	-0.3	-0.8	-0.4	-0.3	0.3
Locomotor activity	0.5	0.9	1.9	0.8	-0.5	-0.0	-1.0	-0.7	-0.7	0.7	0.7	-1.3	-1.1	-0.7	1.4	-1.4
Locomotor testing distance	1.5	2.6	7.3	2.3	-2.1	-1.6	-0.3	-0.1	-0.2	0.2	0.2	-0.6	-2.5	-0.1	2.7	-2.7
Locomotor testing rearing	0.6	0.9	2.3	1.5	-1.4	-1.2	0.2	0.3	0.2	-0.2	-0.2	0.3	-1.3	0.4	1.4	-1.4
Locomotion in novel chamber	0.4	0.4	1.2	-1.1	0.7	0.9	-0.2	-0.3	-0.3	0.3	0.3	-0.1	0.9	-0.3	-1.0	1.0
Locomotion in novel chamber post-restriction	1.2	1.5	3.8	1.1	-1.4	-1.4	1.0	0.7	0.5	-0.5	-0.5	1.4	-1.2	0.7	1.9	-1.9
Fecal boli incidents, locomotor time 1	0.1	0.1	0.5	0.2	-0.2	-0.3	-0.0	0.1	0.2	-0.2	-0.2	-0.2	-0.3	0.2	0.7	-0.7
Change in fecal boli incidents, locomotor task	0.5	0.5	1.1	1.1	-0.8	-0.7	0.6	0.6	0.6	-0.6	-0.6	0.6	-0.7	0.6	0.7	-0.7
Time >=10cm from walls, locomotor time 1	0.9	0.9	1.5	-0.4	1.0	1.0	-1.1	-1.1	-1.2	1.2	1.2	-0.9	0.3	-1.1	-0.5	0.5
Bouts of movement, locomotor time 1	1.4	1.5	2.6	1.5	-1.6	-1.5	0.9	1.0	1.1	-1.1	-1.1	0.7	-1.4	0.9	1.5	-1.5
Total resting periods, locomotor time 1	1.0	1.1	1.5	0.9	-1.1	-1.0	1.1	1.1	1.2	-1.2	-1.2	1.0	-0.9	1.0	0.8	-0.8
Rest time, locomotor task time 1	0.5	0.6	1.2	0.6	-0.4	-0.7	0.9	0.9	1.1	-1.1	-1.1	0.7	-0.3	0.9	0.2	-0.2
Distance moved, locomotor task time 1	0.1	0.1	0.3	-0.1	-0.3	-0.0	0.5	0.6	0.5	-0.5	-0.5	0.4	0.1	0.6	0.1	-0.1
Vertical activity count, locomotor time 1	1.0	1.1	2.1	1.4	-1.3	-1.2	-0.6	-0.7	-0.8	0.8	0.8	-0.5	-1.2	-0.7	1.3	-1.3
Time >=10cm from walls, locomotor time 2	1.3	1.4	2.3	1.2	-1.5	-1.4	1.0	1.1	1.1	-1.1	-1.1	0.9	-1.3	1.1	1.3	-1.3
Bouts of movement, locomotor time 2	1.0	1.1	3.0	-0.2	-0.8	-0.3	1.4	1.2	1.3	-1.3	-1.3	1.7	-0.3	1.2	0.7	-0.7
Total resting periods, locomotor time 2	0.7	0.8	2.1	-0.2	-0.8	-0.2	1.1	0.9	1.0	-1.0	-1.0	1.5	-0.4	0.9	0.8	-0.8
Rest time, locomotor task time 2	0.0	0.0	0.1	0.1	0.0	0.0	-0.1	-0.3	-0.1	0.1	0.1	0.0	-0.2	-0.4	-0.1	0.1
Distance moved, locomotor task time 2	0.0	0.1	0.2	0.0	-0.0	-0.1	0.2	0.4	0.3	-0.3	-0.3	-0.1	0.2	0.4	-0.1	0.1
Vertical activity count, locomotor time 2	0.4	0.4	1.4	1.1	-1.0	-1.2	0.2	0.3	0.2	-0.2	-0.2	0.1	-0.7	0.3	0.8	-0.8
Light reinforcement 1	0.6	1.2	1.7	1.3	-0.8	-0.6	-1.3	-1.2	-1.2	1.2	1.2	-1.3	-1.2	-1.2	0.6	-0.6
Light reinforcement 2	1.1	1.5	3.2	0.0	0.3	0.3	-1.8	-1.6	-1.5	1.5	1.5	-1.8	0.0	-1.5	-0.6	0.6
Bone: marrow area	9.9	21.5	34.0	-2.3	4.1	3.7	-5.7	-5.8	-5.8	5.8	5.8	-5.3	2.6	-5.7	-1.8	1.8
Bone: maximum diameter	5.8	10.7	20.0	-1.2	2.8	2.0	-4.3	-4.0	-4.0	4.0	4.0	-4.5	1.6	-3.9	-1.6	1.6
Bone: maximum force	1.4	2.4	3.5	1.7	-0.8	-1.5	-1.8	-1.7	-1.7	1.7	1.7	-1.9	-1.5	-1.5	1.1	-1.1
Bone: maximum moment	1.1	1.9	3.7	1.9	-1.1	-1.8	-1.3	-1.2	-1.2	1.2	1.2	-1.4	-1.7	-1.0	1.3	-1.3
Mean time between licks in bursts	0.0	0.0	0.2	-0.2	0.4	0.2	-0.0	-0.2	-0.2	0.2	0.2	0.1	0.2	-0.2	-0.3	0.3
Mean num. licks in bursts	3.1	3.8	7.3	2.0	-2.7	-2.6	1.6	1.5	1.5	-1.5	-1.5	1.7	-2.0	1.5	2.2	-2.2
Cd content in liver	4.5	4.9	8.0	2.8	-2.6	-2.7	1.6	1.8	1.8	-1.8	-1.8	1.3	-2.6	1.7	2.7	-2.7
Co content in liver	0.1	0.1	0.2	-0.5	-0.2	0.4	0.2	0.4	0.4	-0.4	-0.4	-0.1	-0.0	0.3	0.2	-0.2
Cu content in liver	0.5	0.6	1.0	-0.5	0.9	0.6	-0.9	-0.7	-0.8	0.8	0.8	-1.0	0.9	-0.7	-0.8	0.8
Fe content in liver	1.9	2.2	5.7	2.0	-1.6	-2.2	0.6	0.7	0.7	-0.7	-0.7	0.4	-1.7	0.7	2.4	-2.4
K content in liver	1.1	1.1	4.7	-2.2	1.3	1.7	-0.1	-0.1	-0.1	0.1	0.1	-0.1	1.2	-0.2	-1.4	1.4
Mg content in liver	0.2	0.2	1.2	-1.1	0.4	0.7	-0.2	-0.2	-0.2	0.2	0.2	-0.2	0.5	-0.3	-0.0	0.0
Mn content in liver	4.3	4.8	6.2	-2.5	2.5	2.1	-2.2	-2.0	-2.0	2.0	2.0	-2.5	2.4	-2.1	-2.1	2.1
Na content in liver	1.7	1.8	4.4	-2.1	1.9	2.0	-0.4	-0.5	-0.5	0.5	0.5	-0.2	1.7	-0.5	-1.8	1.8
Rb content in liver	1.4	1.8	3.3	-0.4	0.6	1.1	-1.8	-1.7	-1.7	1.7	1.7	-1.8	0.1	-1.7	-0.7	0.7
Se content in liver	0.4	0.5	2.6	-1.6	0.8	1.2	-0.1	0.1	0.0	-0.0	-0.0	-0.1	1.2	0.0	-0.7	0.7
Sr content in liver	0.2	0.1	0.5	0.4	-0.3	0.1	-0.3	-0.2	-0.2	0.2	0.2	-0.3	-0.4	-0.2	0.7	-0.7
Zn content in liver	0.3	0.3	0.8	-0.6	0.6	0.9	-0.6	-0.5	-0.4	0.4	0.4	-0.6	0.3	-0.4	-0.5	0.5
Bone: minimum diameter	4.8	9.0	14.0	-1.6	2.6	1.9	-3.7	-3.7	-3.7	3.7	3.7	-3.4	1.9	-3.6	-1.7	1.7
Time in familiar zone, hab. session 1	1.9	1.8	4.3	1.6	-1.6	-1.8	0.7	0.8	0.8	-0.8	-0.8	0.7	-1.4	0.8	2.1	-2.1
Time in novel zone, hab. session 1	1.2	1.1	2.2	-0.8	0.9	1.1	-1.0	-0.9	-0.9	0.9	0.9	-1.1	0.9	-0.9	-1.5	1.5
Total zone transitions, hab. session 1	2.0	2.8	3.6	1.3	-1.8	-1.8	1.7	1.7	1.7	-1.7	-1.7	1.5	-0.9	1.7	1.9	-1.9
Total locomotion distance, hab. session 1	0.9	1.3	3.2	1.6	-1.8	-1.7	0.0	0.2	0.2	-0.2	-0.2	-0.3	-1.4	0.2	1.7	-1.7
Locomotion velocity, hab. session 1	0.6	0.9	2.1	1.2	-1.5	-1.4	0.2	0.5	0.5	-0.5	-0.5	-0.1	-1.0	0.4	1.3	-1.3
Time in familiar zone, hab. session 2	0.3	0.3	0.9	-0.2	-0.3	0.1	0.8	0.7	0.7	-0.7	-0.7	1.0	-0.1	0.7	0.1	-0.1
Time in novel zone, hab. session 2	1.0	1.0	2.6	0.6	0.2	-0.2	-1.4	-1.2	-1.2	1.2	1.2	-1.6	-0.6	-1.2	0.3	-0.3
Total zone transitions, hab. session 2	0.8	1.0	2.0	1.1	-1.2	-1.0	0.8	0.8	0.8	-0.8	-0.8	0.6	-1.1	0.8	1.4	-1.4
Total locomotion distance, hab. session 2	0.2	0.3	0.8	0.7	-0.9	-0.6	-0.2	0.0	0.0	-0.0	-0.0	-0.4	-0.8	-0.0	0.6	-0.6
Locomotion velocity, hab. session 2	0.1	0.1	0.3	0.4	-0.5	-0.2	-0.3	-0.1	-0.1	0.1	0.1	-0.5	-0.5	-0.1	0.3	-0.3
Novel to familiar place preference ratio	0.1	0.1	0.4	-0.4	0.2	0.3	0.1	-0.2	-0.2	0.2	0.2	0.4	0.4	-0.2	-0.6	0.6
Novelty place preference	0.1	0.1	0.3	-0.4	0.3	0.3	-0.0	-0.3	-0.3	0.3	0.3	0.2	0.3	-0.3	-0.6	0.6
Time in novel zone, NPP test	0.0	0.0	0.1	0.1	-0.2	-0.1	0.1	-0.2	-0.2	0.2	0.2	0.3	-0.2	-0.2	-0.1	0.1
Total zone transitions, NPP test	3.3	4.7	6.9	2.2	-2.2	-2.6	2.0	2.2	2.2	-2.2	-2.2	1.6	-1.7	2.2	2.4	-2.4
Total locomotion distance, NPP test	3.6	4.9	10.7	2.8	-2.9	-3.3	1.5	1.7	1.7	-1.7	-1.7	1.1	-2.4	1.6	2.6	-2.6
Locomotion velocity, NPP test	2.6	3.7	7.7	2.2	-2.4	-2.8	1.5	1.7	1.7	-1.7	-1.7	1.2	-1.8	1.6	2.0	-2.0
Intraocular pressure	0.2	0.3	0.8	0.8	-0.5	-0.7	0.1	0.2	0.1	-0.1	-0.1	0.1	-0.7	0.4	0.9	-0.9
Delta distance traveled before/after self-admin	1.4	1.5	2.9	0.6	-0.5	0.0	-1.5	-1.7	-1.6	1.6	1.6	-1.2	-0.7	-1.7	0.9	-0.9
Delta ambulatory time before/after self-admin	2.1	2.3	4.6	-0.4	0.6	1.1	-1.9	-2.1	-2.1	2.1	2.1	-1.6	0.3	-2.1	0.0	-0.0
Parametrial fat weight	0.2	0.4	1.1	0.9	-1.0	-0.7	-0.0	-0.0	0.0	-0.0	-0.0	-0.0	-1.0	0.0	0.9	-0.9
Pavlov. Cond. lever latency	0.5	0.6	1.1	0.3	0.5	0.4	-1.0	-1.0	-1.1	1.1	1.1	-0.6	-0.3	-0.9	0.5	-0.5
Pavlov. Cond. magazine entry latency	0.3	0.4	1.1	-0.9	0.6	0.5	0.2	0.0	0.0	-0.0	-0.0	0.4	1.0	-0.1	-1.1	1.1
Pavlov. Cond. change in total contacts	0.8	0.8	1.1	0.7	-1.0	-0.9	1.0	1.0	1.0	-1.0	-1.0	1.0	-0.8	0.9	0.5	-0.5
Pavlov. Cond. index score	0.2	0.3	1.0	-0.8	0.2	0.3	0.4	0.3	0.3	-0.3	-0.3	0.4	0.6	0.2	-1.0	1.0
Pavlov. Cond. latency score	0.4	0.5	1.2	-0.9	0.2	0.3	0.7	0.6	0.6	-0.6	-0.6	0.6	0.9	0.5	-1.1	1.1
Pavlov. Cond. lever contacts	0.5	0.6	1.0	0.1	-0.8	-0.7	1.0	0.9	1.0	-1.0	-1.0	0.9	-0.2	0.9	-0.1	0.1
Pavlov. Cond. magazine entry number	0.2	0.2	0.6	0.4	-0.2	-0.0	-0.6	-0.4	-0.4	0.4	0.4	-0.8	-0.6	-0.3	0.6	-0.6
Pavlov. Cond. intertrial magazine entries	1.1	1.3	2.5	1.6	-1.5	-1.4	0.8	0.7	0.8	-0.8	-0.8	0.9	-1.3	0.9	1.4	-1.4
Pavlov. Cond. lever-magazine prob. diff.	0.2	0.2	1.0	-0.7	0.2	0.4	0.2	0.1	0.1	-0.1	-0.1	0.2	0.6	0.0	-1.0	1.0
Pavlov. Cond. response bias	0.1	0.2	0.4	0.3	-0.6	-0.6	0.5	0.3	0.4	-0.4	-0.4	0.7	-0.3	0.3	0.0	-0.0
Pavlov. Cond. lever latency	0.7	0.9	2.2	-0.3	-0.1	0.1	1.3	1.2	1.2	-1.2	-1.2	1.5	0.4	1.2	-0.1	0.1
Pavlov. Cond. magazine entry latency	0.5	0.6	1.1	0.6	0.2	-0.0	-0.8	-1.1	-1.1	1.1	1.1	-0.5	-0.8	-1.1	0.6	-0.6
Pavlov. Cond. change in total contacts	0.6	0.9	1.5	0.8	0.1	-0.1	-1.2	-1.1	-1.1	1.1	1.1	-1.2	-1.1	-1.1	0.6	-0.6
Pavlov. Cond. index score	0.5	0.7	1.0	0.8	0.1	-0.2	-1.0	-1.0	-1.0	1.0	1.0	-0.9	-0.8	-1.0	0.6	-0.6
Pavlov. Cond. latency score	0.6	0.7	1.1	0.8	0.0	-0.2	-1.0	-1.0	-1.0	1.0	1.0	-0.9	-0.9	-1.1	0.7	-0.7
Pavlov. Cond. lever contacts	0.4	0.6	1.2	0.3	0.2	-0.0	-1.0	-1.0	-1.0	1.0	1.0	-1.1	-0.2	-1.0	0.1	-0.1
Pavlov. Cond. magazine entry number	0.7	0.9	2.3	-1.3	0.4	0.6	0.7	0.7	0.7	-0.7	-0.7	0.5	1.5	0.7	-1.3	1.3
Pavlov. Cond. intertrial magazine entries	1.3	1.7	3.0	-0.9	1.0	1.0	-1.4	-1.7	-1.7	1.7	1.7	-1.1	1.1	-1.7	-0.1	0.1
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.6	1.0	0.6	0.2	-0.1	-0.9	-1.0	-1.0	1.0	1.0	-0.8	-0.7	-1.0	0.4	-0.4
Pavlov. Cond. response bias	0.5	0.7	1.4	0.4	0.3	-0.0	-1.1	-1.1	-1.1	1.1	1.1	-1.2	-0.4	-1.1	0.1	-0.1
Time in closed arm before self-admin	1.0	1.1	1.4	-1.1	0.9	1.2	-1.2	-1.1	-1.2	1.2	1.2	-1.2	0.7	-1.1	-0.7	0.7
Time in closed arm after self-admin	5.9	6.0	9.5	-1.7	2.1	2.5	-2.8	-3.1	-3.1	3.1	3.1	-2.4	0.9	-3.1	-1.1	1.1
Time in open arm before self-admin	0.7	0.8	1.6	0.3	-0.2	-0.4	1.2	1.3	1.3	-1.3	-1.3	0.9	0.0	1.2	0.2	-0.2
Time in open arm after self-admin	3.1	3.4	5.0	1.2	-1.7	-2.0	2.1	2.2	2.2	-2.2	-2.2	1.9	-0.7	2.2	1.1	-1.1
Bone: periosteal estimation	5.6	11.6	21.1	-0.8	2.5	1.6	-4.6	-4.4	-4.4	4.4	4.4	-4.6	1.2	-4.2	-1.1	1.1
Bone: periosteal perimeter	4.4	7.4	12.5	-1.6	2.6	1.9	-3.4	-3.1	-3.1	3.1	3.1	-3.5	1.9	-3.0	-1.8	1.8
Bone: post-yield work	1.8	2.5	4.8	0.3	0.3	0.4	-2.2	-2.0	-2.0	2.0	2.0	-2.2	-0.2	-2.1	0.8	-0.8
Progressive ratio test 1 active lever presses	0.5	0.5	1.2	1.0	-1.1	-1.0	-0.3	-0.2	-0.2	0.2	0.2	-0.3	-1.1	-0.2	1.0	-1.0
Progressive ratio test 1 breakpoint	0.7	0.7	1.8	1.2	-1.3	-1.2	-0.1	-0.0	-0.0	0.0	0.0	-0.2	-1.3	-0.1	1.2	-1.2
Progressive ratio test 1 inactive lever presses	1.6	1.8	3.6	1.6	-1.1	-1.0	-1.3	-1.3	-1.2	1.2	1.2	-1.3	-1.9	-1.3	1.3	-1.3
Progressive ratio test 2 active lever presses	0.1	0.1	0.3	0.3	-0.3	-0.2	-0.5	-0.5	-0.4	0.4	0.4	-0.5	-0.3	-0.4	0.2	-0.2
Progressive ratio test 2 breakpoint	0.1	0.1	0.2	0.1	-0.1	-0.1	-0.4	-0.5	-0.4	0.4	0.4	-0.4	-0.1	-0.4	-0.0	0.0
Progressive ratio test 2 inactive lever presses	0.5	0.6	1.0	0.7	-0.4	-0.5	-0.9	-1.0	-0.9	0.9	0.9	-0.8	-0.8	-1.0	0.4	-0.4
Incentive Sensitization - Responses	0.6	0.6	0.9	-0.9	0.9	1.0	-0.7	-0.9	-0.7	0.7	0.7	-0.7	0.8	-0.8	-0.8	0.8
Incentive Sensitization - Breakpoint	0.9	0.9	1.5	-1.2	1.2	1.2	-0.8	-0.9	-0.7	0.7	0.7	-0.8	1.1	-0.8	-1.1	1.1
Sum of active levers in priming session hrs 5-6	0.7	0.6	1.5	1.0	-1.2	-0.8	0.7	0.6	0.7	-0.7	-0.7	0.7	-0.9	0.7	0.8	-0.8
Progressive ratio	1.4	1.6	3.9	-1.9	2.0	1.8	-0.7	-0.4	-0.8	0.8	0.8	-0.7	1.5	-0.5	-1.6	1.6
Food seeking constrained by brief footshock	1.2	1.4	4.2	-2.1	1.9	1.9	-0.0	0.1	-0.2	0.2	0.2	-0.1	1.6	0.1	-1.6	1.6
Seeking ratio, punishment vs. effort	0.1	0.1	0.4	-0.0	-0.2	-0.1	0.6	0.3	0.5	-0.5	-0.5	0.6	0.0	0.4	-0.1	0.1
Retroperitoneal fat weight	0.3	1.1	3.4	1.8	-1.7	-1.8	-0.0	-0.1	-0.2	0.2	0.2	-0.0	-1.4	-0.1	1.2	-1.2
Reaction time number correct	0.7	1.0	2.3	1.4	-1.3	-1.5	0.6	0.3	0.3	-0.3	-0.3	0.7	-1.3	0.4	1.5	-1.5
Reaction time mean minus median	0.4	0.5	1.2	-0.0	0.1	-0.1	-1.1	-0.9	-1.0	1.0	1.0	-1.0	0.5	-0.9	0.0	-0.0
Reaction time mean minus median AUC	1.6	2.1	4.2	-0.1	0.7	0.4	-2.1	-1.8	-1.9	1.9	1.9	-2.0	0.4	-1.9	-0.4	0.4
Reaction time num false alarms	0.1	0.2	0.5	-0.1	0.6	0.7	-0.3	-0.5	-0.5	0.5	0.5	-0.1	0.3	-0.4	-0.1	0.1
Reaction time num false alarms AUC	0.1	0.1	0.7	-0.3	0.7	0.8	-0.0	-0.2	-0.2	0.2	0.2	0.1	0.5	-0.1	-0.1	0.1
Reaction time trials correct on left	0.7	1.0	2.3	1.4	-1.3	-1.5	0.6	0.3	0.3	-0.3	-0.3	0.7	-1.3	0.4	1.5	-1.5
Reaction time trials on left	0.7	1.0	2.4	1.4	-1.3	-1.5	0.5	0.3	0.3	-0.3	-0.3	0.7	-1.3	0.3	1.5	-1.5
Reaction time mean	0.6	0.9	1.6	0.5	-0.2	-0.2	-1.2	-1.2	-1.2	1.2	1.2	-1.1	-0.0	-1.3	0.5	-0.5
Reaction time mean AUC	0.9	1.2	2.1	0.7	-0.4	-0.3	-1.4	-1.4	-1.4	1.4	1.4	-1.3	-0.5	-1.5	0.8	-0.8
Median of all reaction times	0.7	0.9	1.7	0.5	-0.1	-0.2	-1.2	-1.3	-1.3	1.3	1.3	-1.1	-0.2	-1.3	0.5	-0.5
Reaction time omissions	0.8	1.1	2.2	0.2	0.8	0.3	-1.1	-1.5	-1.5	1.5	1.5	-0.8	0.4	-1.5	-0.2	0.2
Reaction time false alarm rate	0.4	0.6	2.0	-1.0	1.3	1.4	-0.1	-0.1	-0.2	0.2	0.2	-0.1	1.1	-0.1	-0.9	0.9
Reaction time premature initiation rate	1.8	2.5	4.6	-0.5	-0.7	0.0	2.1	2.1	2.1	-2.1	-2.1	1.9	0.5	2.1	0.2	-0.2
Reaction time premature initiations	1.4	2.0	3.4	0.4	-1.3	-0.7	1.9	1.7	1.7	-1.7	-1.7	1.8	-0.4	1.8	1.0	-1.0
Std. dev. reaction times	0.2	0.3	0.6	0.2	-0.1	-0.3	-0.7	-0.6	-0.7	0.7	0.7	-0.7	0.2	-0.7	0.3	-0.3
Reaction time trials completed	0.7	1.0	2.4	1.4	-1.3	-1.5	0.5	0.3	0.3	-0.3	-0.3	0.7	-1.3	0.3	1.5	-1.5
Reaction time trials AUC	0.7	1.0	2.3	1.5	-1.3	-1.5	0.5	0.2	0.2	-0.2	-0.2	0.7	-1.3	0.3	1.5	-1.5
Run reversals in cocaine runway, females	0.7	0.7	1.2	-0.1	-0.5	-0.4	1.1	1.1	1.1	-1.1	-1.1	1.1	-0.2	1.1	0.1	-0.1
Run reversals in cocaine runway, males	0.1	0.1	0.2	-0.1	-0.2	0.2	-0.4	-0.1	-0.3	0.3	0.3	-0.4	-0.1	-0.1	-0.5	0.5
Latency to leave start box in cocaine runway	0.3	0.3	0.7	0.6	-0.5	-0.1	-0.4	-0.5	-0.8	0.8	0.8	0.1	-0.8	-0.5	0.6	-0.6
Latency to leave start box in cocaine runway, F	1.0	1.0	2.3	1.5	-1.4	-1.2	0.9	0.7	0.7	-0.7	-0.7	1.0	-1.2	0.7	1.1	-1.1
Latency to leave start box in cocaine runway, M	2.2	2.1	4.9	-0.5	0.7	1.2	-1.8	-1.7	-2.2	2.2	2.2	-1.3	0.0	-1.7	-0.3	0.3
Std. dev. time between licks in bursts	1.0	1.1	3.1	1.7	-1.4	-1.4	0.2	0.4	0.4	-0.4	-0.4	-0.1	-1.8	0.4	1.4	-1.4
Total sessions with >9 infusions	0.7	0.7	1.5	-0.5	0.5	0.6	-1.2	-1.1	-1.0	1.0	1.0	-1.2	0.2	-1.1	-0.2	0.2
Short access day 1 total inactive lever presses	1.2	1.4	2.2	1.5	-0.9	-1.0	-1.3	-1.2	-1.1	1.1	1.1	-1.3	-1.4	-1.2	0.9	-0.9
Short access day 10 total inactive lever presses	1.2	1.3	3.8	1.9	-1.5	-1.4	-0.4	-0.3	-0.1	0.1	0.1	-0.5	-2.0	-0.3	1.6	-1.6
Short access day 1 total infusions	0.7	0.8	2.3	-0.0	0.4	0.3	-1.3	-1.1	-1.0	1.0	1.0	-1.5	-0.3	-1.1	-0.1	0.1
Short access day 10 total infusions	2.0	2.2	4.9	0.0	0.3	0.5	-2.1	-2.0	-1.9	1.9	1.9	-2.2	-0.2	-2.0	-0.1	0.1
Short access total infusions	1.6	1.8	4.5	0.3	0.0	0.1	-2.0	-1.8	-1.7	1.7	1.7	-2.1	-0.6	-1.8	0.3	-0.3
Short access day 1 locomotion	0.6	0.6	1.2	0.3	-0.3	-0.2	-1.0	-1.1	-1.0	1.0	1.0	-1.1	-0.4	-1.1	0.0	-0.0
Short access day 10 total locomotion	0.3	0.4	1.1	-0.2	0.2	0.1	-0.9	-0.8	-0.6	0.6	0.6	-1.1	0.2	-0.8	-0.4	0.4
Short access total locomotion	0.3	0.3	1.0	0.1	-0.1	-0.1	-0.8	-0.7	-0.5	0.5	0.5	-1.0	-0.2	-0.7	-0.1	0.1
One hour access (0.3 mA shock)	0.4	0.4	1.3	0.3	-0.2	-0.0	-1.0	-0.8	-0.7	0.7	0.7	-1.1	-0.5	-0.8	0.2	-0.2
Compulsive drug intake	2.0	2.0	4.0	2.0	-1.7	-1.8	0.9	0.9	0.8	-0.8	-0.8	1.0	-1.9	1.0	1.8	-1.8
One hour access (shock baseline)	1.4	1.7	2.3	-1.5	1.5	1.5	-1.3	-1.2	-1.1	1.1	1.1	-1.3	1.3	-1.2	-1.3	1.3
Social response proportion	0.1	0.1	0.4	-0.1	0.3	0.2	-0.6	-0.3	-0.3	0.3	0.3	-0.7	0.5	-0.3	-0.3	0.3
Social responses	0.8	1.1	3.5	1.9	-1.3	-1.4	-0.1	0.4	0.4	-0.4	-0.4	-0.6	-1.3	0.4	1.4	-1.4
Social time	0.9	1.2	3.2	0.8	-0.6	-0.5	-1.4	-1.1	-1.1	1.1	1.1	-1.8	-0.5	-1.1	1.2	-1.2
Soleus weight	1.0	3.0	4.5	-1.6	1.8	2.1	-1.9	-1.8	-1.8	1.8	1.8	-2.1	0.9	-1.8	-1.5	1.5
Bone: stiffness	1.7	2.7	5.1	0.8	0.3	-0.0	-2.3	-2.2	-2.2	2.2	2.2	-2.2	-0.7	-2.1	0.5	-0.5
Tibialis anterior weight	0.2	0.5	1.1	-0.6	0.7	1.0	-0.8	-0.6	-0.6	0.6	0.6	-0.8	0.3	-0.6	-0.9	0.9
Time to tail flick, vehicle, before self-admin	0.9	1.0	1.7	1.2	-1.2	-1.3	1.0	0.7	0.6	-0.6	-0.6	1.1	-1.1	0.7	1.1	-1.1
Time to tail flick, vehicle, after self-admin	0.6	0.7	1.7	-1.3	1.1	1.2	0.1	-0.0	-0.0	0.0	0.0	-0.0	1.2	-0.1	-1.3	1.3
Time to tail flick, test, before self-admin	1.5	1.4	3.9	-2.0	1.2	1.2	1.4	1.0	1.0	-1.0	-1.0	1.5	1.6	1.0	-0.3	0.3
Time to tail flick, test, after self-admin	1.0	1.0	1.7	-0.7	0.6	0.3	1.3	1.3	1.3	-1.3	-1.3	1.2	0.8	1.2	-0.6	0.6
Delta time to tail flick, vehicle, before/after SA	0.3	0.3	0.6	-0.7	0.6	0.7	0.2	0.2	0.3	-0.3	-0.3	0.1	0.8	0.2	-0.7	0.7
Delta time to tail flick, test, before/after SA	0.3	0.3	0.7	0.8	-0.3	-0.6	0.2	0.6	0.6	-0.6	-0.6	-0.1	-0.7	0.6	-0.3	0.3
Tibia length	0.8	2.2	6.9	-1.5	2.0	1.2	-0.9	-0.7	-0.7	0.7	0.7	-1.0	1.7	-0.6	-2.6	2.6
Ambulatory time before self-admin	0.4	0.4	0.8	-0.1	0.2	0.1	0.7	0.9	0.9	-0.9	-0.9	0.5	0.2	0.8	-0.6	0.6
Ambulatory time after self-admin	0.2	0.2	0.5	-0.5	0.4	0.7	-0.2	-0.4	-0.2	0.2	0.2	-0.2	0.4	-0.3	-0.6	0.6
Bone: tissue strength	1.7	1.7	5.3	2.0	-2.2	-2.0	-0.1	0.1	0.1	-0.1	-0.1	-0.2	-2.3	0.1	1.4	-1.4
Total heroin consumption	0.9	1.0	3.0	-1.2	1.3	1.3	0.6	0.2	0.2	-0.2	-0.2	1.1	1.0	0.3	-1.7	1.7
Bone: trabecular number	0.1	0.2	0.7	-0.6	0.8	0.4	0.0	-0.1	-0.1	0.1	0.1	0.1	0.9	0.0	-0.5	0.5
Bone: trabecular spacing	0.1	0.1	0.4	0.4	-0.4	-0.2	-0.0	0.1	0.1	-0.1	-0.1	-0.1	-0.6	-0.1	0.3	-0.3
Bone: trabecular thickness	0.0	0.1	0.3	-0.4	0.2	0.1	0.1	0.1	0.1	-0.1	-0.1	0.1	0.5	0.2	-0.2	0.2
Bone: trabecular tissue density	0.1	0.1	0.3	0.1	-0.5	-0.4	0.3	0.5	0.5	-0.5	-0.5	0.0	0.2	0.5	-0.0	0.0
Water consumed over 24 hours	0.1	0.1	0.5	-0.6	0.1	-0.0	0.3	0.3	0.3	-0.3	-0.3	0.4	0.7	0.3	-0.2	0.2
Number of responses in last shaping day	2.2	2.3	4.0	-0.3	0.7	0.6	-2.0	-2.0	-2.0	2.0	2.0	-1.9	0.6	-2.0	-0.9	0.9