Hub : Genes

LOC102549281

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression LOC102549281 0.07 0.04 4.3e-03 0 0.01 0 -0 2.9e-01 1.1e-01 2.6e-01 4.3e-01
2 Liver intron excision ratio chr14_78975267_78980174 0.04 0.02 1.4e-04 0.03 0.03 0.03 0.03 4.3e-04 5.6e-04 6.1e-04 4.7e-04
3 BLA alternative TSS XR_005493380.1 0.09 0.04 6.9e-05 0.05 0.05 0.06 0.05 7.4e-04 1.7e-03 4.9e-04 1.5e-03
4 Brain gene expression LOC102549281 0.13 0.05 7.7e-15 0.16 0.16 0.16 0.18 5.2e-15 3.9e-15 4.5e-15 3.4e-16
5 Liver intron excision ratio chr14_78980343_78980455 0.04 0.02 1.4e-04 0.03 0.03 0.03 0.03 3.2e-04 5.8e-04 4.4e-04 4.9e-04
6 BLA alternative TSS XR_005493380.1 0.08 0.05 6.6e-04 0.06 0.04 0.07 0.06 3.8e-04 3.4e-03 1.6e-04 2.2e-04
7 BLA gene expression LOC102549281 0.13 0.06 1.5e-06 0.12 0.08 0.07 0.11 6.9e-07 3.2e-05 7.6e-05 2.3e-06
8 OFC gene expression LOC102549281 0.3 0.15 1.3e-03 0.08 0.08 0.08 0.07 6.9e-03 6.6e-03 5.4e-03 9.8e-03
9 BLA alternative TSS XR_005493381.1 0.09 0.05 1.0e-04 0.09 0.06 0.08 0.09 1.4e-05 3.3e-04 4.2e-05 1.2e-05
10 PL gene expression LOC102549281 0.13 0.07 4.5e-14 0.14 0.11 0.12 0.13 7.5e-15 1.9e-12 1.4e-13 6.5e-14
11 Liver gene expression LOC102549281 0.06 0.03 1.1e-06 0.04 0.04 0.03 0.04 1.1e-05 1.6e-05 1.2e-04 1.2e-05
12 Brain intron excision ratio chr14_78975267_78980455 0.03 0.02 6.2e-03 0.02 0.02 0.01 0.01 3.4e-03 9.2e-03 7.2e-02 2.0e-02
13 PL intron excision ratio chr14_78975267_78980455 0.05 0.03 5.2e-05 0.02 0.03 0.03 0.02 1.5e-03 2.0e-04 6.9e-04 1.6e-03
14 Brain isoform ratio XR_359644.4 0.04 0.03 6.4e-03 0.01 0.02 0.02 0.02 1.2e-02 6.0e-03 4.5e-03 2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bone: apparent density0.30.51.00.01.00.30.7-0.90.6-0.7-0.70.8-0.7-1.00.6-0.8-0.3
Area under the delay curve9.910.412.8-3.1-3.3-3.0-3.43.2-3.43.23.2-3.53.33.6-3.23.1-2.8
BMI with tail0.61.94.0-1.5-0.8-1.1-1.80.5-1.51.11.1-1.91.12.0-2.00.9-0.7
BMI without tail0.20.41.6-1.3-0.2-0.6-0.80.1-0.70.20.2-0.60.30.6-0.9-0.1-0.4
Body weight1.87.511.5-3.4-2.3-3.2-3.11.9-3.12.72.7-2.92.72.7-3.01.9-2.4
Weight adjusted by age1.11.22.2-1.5-0.7-1.1-1.20.4-1.20.81.0-1.41.11.4-1.30.7-0.8
Bone surface0.30.50.8-0.7-0.4-0.9-0.80.6-0.70.80.8-0.60.80.5-0.70.5-0.6
Bone volume0.10.10.4-0.6-0.1-0.6-0.30.3-0.40.30.3-0.10.3-0.1-0.20.2-0.7
Breakpoint value in progressive ratio session0.20.30.6-0.5-0.8-0.4-0.20.7-0.10.20.1-0.60.10.7-0.60.7-0.7
Number of licking bursts0.91.13.2-1.8-1.5-1.2-0.81.4-0.90.90.7-0.50.70.3-0.50.5-1.4
Context. condit. distance diff. score2.22.73.71.71.91.71.7-1.91.8-1.8-1.71.5-1.7-1.01.5-1.61.4
Locomotion velocity, session 10.30.32.21.50.20.80.3-0.10.2-0.2-0.20.1-0.2-0.20.20.51.0
Locomotion distance, session 11.21.53.81.31.91.21.2-1.71.1-1.2-1.20.8-1.2-0.80.9-1.20.8
Locomotion velocity, session 20.50.63.01.7-0.11.00.7-0.10.5-0.6-0.50.7-0.5-0.80.70.60.6
Locomotion distance, session 21.92.76.12.51.61.91.6-1.31.6-1.5-1.41.5-1.5-1.61.5-1.01.9
Locomotion velocity, session 30.70.82.51.01.50.90.8-1.60.9-0.9-0.90.6-0.8-0.30.5-0.90.5
Locomotion distance, session 30.60.60.9-0.0-0.6-0.5-0.90.6-0.90.90.9-0.90.91.0-1.00.90.1
Stereotopy head waving bouts, day 31.41.72.71.31.61.31.3-1.51.1-1.3-1.31.3-1.3-1.21.3-1.21.0
Stereotopy head waving duration, day 32.63.14.71.92.21.91.7-2.11.7-1.8-1.81.6-1.7-1.61.5-1.71.5
Locomotion velocity, session 70.10.10.20.4-0.00.2-0.10.3-0.30.20.2-0.20.20.1-0.30.40.2
Locomotion distance, session 70.50.61.71.31.11.00.6-0.70.6-0.6-0.60.6-0.6-0.70.5-0.50.9
Stereotopy head waving bouts, day 70.00.00.1-0.30.0-0.3-0.3-0.1-0.20.20.1-0.30.20.3-0.40.1-0.2
Stereotopy head waving duration, day 70.30.30.7-0.8-0.3-0.7-0.70.2-0.60.50.4-0.70.50.7-0.70.2-0.4
Locomotion velocity, session 82.22.65.32.31.01.91.7-0.91.7-1.5-1.51.9-1.5-1.51.8-0.91.8
Locomotion distance, session 87.711.313.43.73.63.63.5-3.43.6-3.4-3.43.3-3.4-3.03.2-3.13.1
Degree of sensitization distance5.75.76.92.32.42.42.5-2.32.5-2.4-2.42.6-2.4-2.62.5-2.21.7
Degree of sensitization stereotypy0.60.61.3-1.1-0.8-0.9-0.80.7-0.70.70.6-0.90.60.8-0.80.5-0.7
Conditioned locomotion0.20.20.6-0.20.80.20.3-0.70.4-0.4-0.40.2-0.40.10.2-0.7-0.3
Cocaine response after cond. corrected1.31.41.9-1.2-0.7-1.4-1.20.8-1.21.31.3-1.21.31.2-1.21.1-1.3
Cocaine response after cond. not corrected2.62.94.3-1.9-1.1-2.1-1.71.1-1.81.71.8-1.71.81.8-1.71.3-2.1
Cocaine response before conditioning0.10.10.2-0.4-0.0-0.4-0.3-0.1-0.40.10.2-0.40.20.4-0.4-0.1-0.4
Saline control response0.91.23.81.91.51.40.8-1.30.9-0.9-0.80.5-0.8-0.20.6-0.51.6
Bone: connectivity density0.20.21.00.11.00.10.4-0.90.4-0.4-0.40.4-0.4-0.50.3-0.7-0.1
Bone: cortical apparent density0.00.00.1-0.4-0.20.10.00.20.0-0.2-0.30.1-0.30.0-0.0-0.10.0
Bone: cortical area2.94.45.9-2.4-1.8-2.4-2.21.9-2.22.12.1-2.32.12.3-2.21.5-1.5
Bone: cortical porosity0.50.61.2-1.0-0.6-1.0-0.70.5-0.80.70.8-0.70.80.7-0.70.4-1.1
Bone: cortical porosity0.10.10.3-0.5-0.3-0.5-0.30.3-0.30.30.4-0.20.40.2-0.30.0-0.4
Bone: cortical thickness2.13.45.8-2.4-1.4-2.3-1.91.6-1.91.91.8-1.91.82.0-1.90.9-1.5
Bone: cortical thickness0.10.20.8-0.50.8-0.20.1-0.70.1-0.2-0.2-0.1-0.20.1-0.1-0.90.1
Bone: cortical tissue density0.00.00.1-0.4-0.30.1-0.10.3-0.0-0.1-0.20.0-0.20.1-0.10.0-0.1
Condit. Reinf. active minus inactive responses0.20.30.60.80.20.0-0.50.0-0.40.60.6-0.60.60.3-0.60.80.5
Condit. Reinf. active-inactive response ratio0.60.63.71.90.31.00.20.00.4-0.0-0.10.3-0.1-0.50.20.51.7
Condit. Reinf. active responses0.10.10.60.80.60.2-0.1-0.3-0.10.30.3-0.20.3-0.2-0.20.20.7
Condit. Reinf. inactive responses0.10.10.7-0.80.1-0.6-0.1-0.2-0.30.10.2-0.20.20.0-0.1-0.4-0.6
Incentive salience index mean0.70.81.4-0.0-0.3-0.7-1.10.4-1.11.11.2-1.21.20.9-1.21.1-0.1
Condit. Reinf. lever presses0.60.81.5-0.7-0.3-0.9-1.00.1-1.10.91.1-1.21.10.9-1.10.7-0.5
Condit. Reinf. active minus inactive responses0.81.01.41.01.11.21.0-1.10.9-1.0-1.10.6-1.1-0.90.8-0.91.0
Condit. Reinf. active-inactive response ratio0.10.10.30.10.20.1-0.2-0.2-0.20.20.1-0.50.10.3-0.40.2-0.1
Condit. Reinf. active responses1.92.64.22.01.82.01.5-1.91.4-1.6-1.71.2-1.7-1.31.3-1.31.7
Condit. Reinf. inactive responses2.83.45.02.21.92.11.8-1.91.8-1.8-1.81.8-1.8-1.81.7-1.52.0
Condit. Reinf. lever presses0.50.71.11.01.01.00.7-1.00.7-0.8-0.80.5-0.8-0.50.6-0.80.9
Condit. Reinf. lever reinforcers received1.42.03.51.91.81.81.3-1.81.2-1.3-1.40.8-1.4-0.91.0-1.11.4
Conditioned reinforcement - actives1.91.92.9-1.1-1.2-1.4-1.51.3-1.21.71.5-1.51.41.5-1.31.3-1.3
Conditioned reinforcement - inactives3.23.54.6-1.5-1.6-1.9-2.01.7-1.72.22.0-2.12.02.2-2.01.9-1.5
Conditioned locomotion0.60.81.6-1.0-0.7-1.0-1.10.8-1.00.80.7-0.80.80.8-0.60.6-1.3
Patch foraging indifference point 0 sec0.00.10.3-0.5-0.4-0.1-0.10.3-0.2-0.0-0.20.0-0.30.10.00.1-0.3
Patch foraging indifference point AUC0.50.61.91.40.51.10.4-0.80.0-0.9-0.90.3-0.9-0.20.10.11.1
Delay disc. indifference point, 0s delay7.88.610.8-3.1-2.5-2.9-3.22.5-2.92.92.9-3.33.03.3-3.02.4-3.0
Delay disc. indifference point, 16s delay6.06.17.6-2.0-2.7-2.2-2.52.6-2.82.42.5-2.62.42.6-2.22.7-2.1
Delay disc. indifference point, 2s delay7.27.910.1-3.2-2.3-3.0-3.02.4-2.72.92.9-3.12.93.1-2.92.2-2.7
Delay disc. indifference point, 24s delay5.85.67.8-2.0-2.1-2.4-2.52.1-2.22.82.6-2.62.42.6-2.52.3-2.0
Delay disc. indifference point, 4s delay6.77.08.8-2.6-2.3-2.7-2.82.3-2.82.82.7-3.02.82.9-2.72.3-2.3
Delay disc. indifference point, 8s delay1.81.83.1-1.0-1.8-0.8-1.41.6-1.51.11.2-1.61.41.6-1.41.5-0.7
Indifference point function ln k0.20.21.1-0.70.5-0.70.0-0.30.10.30.40.10.5-0.20.0-0.5-1.1
Indifference point function log k0.20.21.1-0.70.5-0.70.0-0.30.10.30.40.10.5-0.20.0-0.5-1.1
Patch foraging total patch changes 0 sec0.10.10.4-0.4-0.6-0.1-0.20.5-0.40.1-0.1-0.2-0.20.3-0.10.3-0.2
Patch foraging total patch changes 12 sec0.10.10.3-0.4-0.30.1-0.20.1-0.4-0.3-0.5-0.4-0.60.4-0.20.1-0.1
Patch foraging total patch changes 18 sec0.30.41.40.3-1.2-0.0-0.70.9-0.80.30.2-0.60.20.6-0.61.10.5
Patch foraging total patch changes 24 sec2.73.35.02.21.62.21.7-1.91.7-1.9-2.01.4-2.1-1.41.5-1.32.2
Patch foraging total patch changes 6 sec0.10.10.30.2-0.30.1-0.3-0.1-0.50.0-0.1-0.3-0.10.5-0.20.5-0.0
Patch foraging time to switch 0 sec0.20.30.8-0.7-0.3-0.00.50.30.9-0.1-0.20.7-0.1-0.80.7-0.90.1
Patch foraging water rate 0 sec0.30.41.30.1-0.5-0.2-0.70.3-1.10.30.3-0.90.21.1-0.90.90.0
Patch foraging water rate 12 sec0.10.10.70.70.50.1-0.1-0.4-0.2-0.0-0.0-0.20.00.2-0.1-0.20.8
Patch foraging water rate 18 sec1.01.33.40.11.70.61.2-1.61.0-1.1-1.11.0-1.1-1.01.0-1.80.3
Patch foraging water rate 24 sec0.30.32.11.00.30.50.5-0.20.4-0.3-0.20.3-0.2-0.30.6-0.51.5
Patch foraging water rate 6 sec0.00.10.50.20.4-0.10.0-0.1-0.20.00.0-0.10.10.10.1-0.40.7
Seeking ratio, delayed vs. immediate footshock0.30.41.60.80.11.10.5-0.10.5-1.3-0.80.2-0.7-0.10.40.2-0.2
Distance traveled before self-admin0.10.10.4-0.0-0.10.50.20.10.0-0.6-0.30.1-0.3-0.1-0.00.4-0.1
Distance traveled after self-admin0.20.30.5-0.6-0.7-0.1-0.40.6-0.50.00.2-0.70.20.7-0.60.6-0.3
Extensor digitorum longus weight2.610.313.2-3.5-2.8-3.6-3.43.0-3.63.43.2-3.23.23.1-3.32.5-2.9
Bone: elastic displacement0.50.51.4-0.00.70.30.7-0.70.8-0.7-0.71.0-0.7-0.90.7-1.20.3
Bone: elastic work0.20.21.1-1.10.2-0.60.1-0.10.0-0.1-0.10.3-0.1-0.40.1-0.9-0.3
Bone: endosteal estimation0.00.00.0-0.1-0.1-0.1-0.00.2-0.1-0.0-0.00.0-0.0-0.20.10.10.0
Bone: endosteal perimeter0.61.31.6-1.0-1.2-1.2-1.21.2-1.21.21.2-1.21.21.0-1.01.1-0.8
Epididymis fat weight0.10.21.9-1.4-0.5-0.6-0.20.1-0.00.10.00.1-0.1-0.1-0.1-0.4-0.7
Delta time in closed arm before/after self-admin3.23.15.71.32.31.42.0-2.42.2-1.8-1.91.4-1.8-1.31.4-1.80.7
Delta time in open arm before/after self-admin4.94.78.4-1.6-2.9-1.8-2.22.8-2.42.12.2-2.12.22.2-1.92.3-1.2
Diff in mean of infusions in LGA sessions0.20.20.4-0.5-0.6-0.4-0.30.6-0.20.40.3-0.50.40.6-0.50.4-0.3
Delay discount exponential model param9.39.812.33.03.12.93.3-3.03.3-3.1-3.13.5-3.2-3.53.2-2.92.6
Extinction: sum of active levers before priming1.61.63.3-0.5-1.2-0.9-1.21.1-1.11.11.1-1.71.11.6-1.51.8-1.2
Active lever presses in extinction session 61.71.63.3-1.5-1.1-1.5-1.21.0-1.01.21.2-1.31.11.4-1.41.0-1.8
Bone: final force0.10.10.2-0.4-0.4-0.3-0.40.5-0.30.30.3-0.30.30.3-0.3-0.00.4
Bone: final moment0.10.20.5-0.7-0.6-0.5-0.40.7-0.40.40.3-0.30.30.2-0.30.00.0
Food consumed during 24 hour testing period0.10.10.60.8-0.50.40.10.4-0.10.1-0.00.2-0.0-0.20.10.60.6
Glucose11.517.332.9-1.1-5.4-3.1-4.25.1-4.34.54.5-3.84.43.9-4.15.7-1.5
Heart weight0.30.51.01.00.70.50.7-0.90.9-0.4-0.30.7-0.2-0.70.7-0.50.7
Delay discount hyperbolic model param9.910.413.23.13.13.13.4-3.13.3-3.2-3.23.6-3.3-3.63.3-3.02.7
Intermittent access intake day 1-15 change0.90.91.8-0.3-1.0-0.8-1.10.9-0.91.10.9-1.10.91.0-1.21.3-0.4
Intermittent access intake escalation0.50.51.0-0.2-0.8-0.5-0.80.6-0.50.70.7-0.70.60.7-0.91.0-0.4
Intermittent access intake escalation 20.10.10.20.3-0.30.40.20.10.3-0.3-0.30.4-0.3-0.40.20.10.3
Intermitt. access day 1 inactive lever presses0.30.31.50.81.20.40.3-1.10.5-0.4-0.3-0.0-0.30.1-0.2-0.20.4
Intermitt. access day 15 inactive lever presses0.60.71.10.4-0.6-0.3-0.80.7-0.71.00.9-0.90.91.0-1.01.10.6
Intermitt. access escalation Index0.20.20.90.70.40.50.2-0.50.2-0.3-0.20.1-0.2-0.10.2-0.21.0
Intermittent access day 1 total infusions0.40.41.5-0.9-1.0-0.6-0.71.2-0.60.40.6-0.50.50.5-0.40.4-0.2
Intermittent access day 15 total infusions1.51.73.1-1.1-1.6-1.2-1.61.7-1.21.41.4-1.21.31.2-1.21.3-0.5
Intermittent access terminal intake (last 3 days)0.50.51.5-0.5-1.1-0.6-0.91.2-0.60.60.7-0.60.60.5-0.60.8-0.1
Intermittent access total infusions0.80.81.8-0.9-1.2-1.0-1.01.3-0.80.91.0-0.70.90.7-0.70.8-0.6
Intermittent access day 1 locomotion1.01.11.61.00.71.20.9-0.51.0-1.3-1.11.2-1.1-1.21.3-0.91.0
Intermittent access day 15 total locomotion2.22.43.5-1.5-1.9-1.4-1.81.8-1.51.11.6-1.71.61.7-1.61.4-0.9
Intermittent access total locomotion0.81.01.6-0.6-1.3-0.8-1.11.3-0.90.81.0-1.01.01.0-0.91.1-0.4
Intermittent access standard deviation0.60.61.10.90.70.80.6-0.60.8-0.5-0.70.8-0.8-0.80.8-0.81.0
Left kidney weight0.41.12.8-0.01.30.31.1-1.01.2-0.9-0.81.4-0.6-1.31.1-1.70.6
Right kidney weight0.51.43.9-0.61.70.21.1-1.61.3-1.1-1.01.3-0.9-1.41.0-2.0-0.0
Cocaine induced anxiety0.80.91.6-0.1-1.1-0.6-0.91.1-1.31.11.1-0.81.00.8-0.91.3-0.2
Post-drug Anxiety0.50.61.1-0.2-0.9-0.7-0.61.0-0.61.10.8-0.70.60.7-0.81.0-0.6
Baseline Anxiety0.40.50.9-1.0-0.9-0.9-0.51.0-0.10.80.5-0.50.40.5-0.40.5-0.9
Tail length0.51.54.6-2.2-0.8-1.9-1.10.9-1.41.11.1-0.71.20.5-0.90.4-1.8
Length with tail0.93.47.0-2.6-1.7-2.6-1.71.5-1.91.92.0-1.32.01.1-1.51.0-2.1
Length without tail1.12.43.2-1.4-1.7-1.8-1.51.5-1.51.71.8-1.41.71.4-1.41.4-1.2
Times rat made contact with spout0.40.52.41.6-0.61.00.40.50.3-0.2-0.20.6-0.3-0.30.50.81.2
Lifetime Intake0.60.71.4-1.0-1.0-1.0-0.91.2-0.80.90.8-0.70.80.7-0.60.8-0.7
Liver weight, left3.55.68.61.12.92.12.5-2.62.5-2.7-2.72.4-2.6-2.12.2-2.71.1
Liver weight, right4.06.710.91.63.12.42.7-2.72.9-2.6-2.62.5-2.6-2.22.6-3.32.1
Locomotor activity0.30.51.60.2-1.2-0.5-0.60.9-0.70.80.9-0.10.80.2-0.21.00.2
Locomotor testing distance0.30.51.1-1.1-0.6-1.0-0.70.6-0.90.70.8-0.40.60.5-0.50.2-0.9
Locomotor testing rearing1.82.83.9-1.3-1.6-1.8-1.71.8-1.71.92.0-1.41.91.4-1.61.6-1.4
Locomotion in novel chamber0.30.41.10.11.00.30.6-1.10.9-0.5-0.50.6-0.6-0.50.4-1.00.2
Locomotion in novel chamber post-restriction1.51.84.12.01.11.81.3-0.91.4-1.3-1.41.2-1.4-1.11.1-0.71.3
Fecal boli incidents, locomotor time 10.60.61.11.00.80.90.9-1.00.7-0.7-0.90.7-0.7-0.60.8-0.40.6
Change in fecal boli incidents, locomotor task0.70.71.91.40.21.10.6-0.11.0-0.7-0.61.0-0.6-1.00.5-0.21.3
Time >=10cm from walls, locomotor time 10.10.20.5-0.3-0.00.30.3-0.00.6-0.7-0.30.5-0.2-0.40.1-0.5-0.3
Bouts of movement, locomotor time 10.30.30.70.2-0.2-0.4-0.70.3-0.60.80.7-0.40.70.4-0.70.70.2
Total resting periods, locomotor time 10.50.61.10.3-0.4-0.5-1.00.5-0.71.11.0-0.61.00.6-1.00.90.3
Rest time, locomotor task time 10.10.10.90.90.40.10.0-0.30.30.60.00.0-0.10.10.00.20.5
Distance moved, locomotor task time 10.20.20.6-0.8-0.3-0.00.40.3-0.1-0.7-0.60.4-0.6-0.50.7-0.50.0
Vertical activity count, locomotor time 10.30.30.8-0.2-0.50.50.50.30.1-0.9-0.80.5-0.7-0.70.8-0.20.3
Time >=10cm from walls, locomotor time 20.20.30.50.60.10.60.5-0.10.7-0.7-0.70.4-0.5-0.30.4-0.4-0.1
Bouts of movement, locomotor time 20.40.41.0-0.30.4-0.3-0.7-0.3-0.7-0.10.4-0.90.71.0-0.90.1-1.0
Total resting periods, locomotor time 20.50.51.3-0.20.4-0.3-0.8-0.2-0.80.20.6-1.10.91.1-1.00.3-0.8
Rest time, locomotor task time 20.40.51.11.00.90.60.5-0.90.6-0.2-0.40.7-0.4-0.60.4-0.51.0
Distance moved, locomotor task time 20.10.20.5-0.1-0.20.10.40.20.2-0.5-0.60.3-0.6-0.40.7-0.40.2
Vertical activity count, locomotor time 20.10.10.3-0.4-0.6-0.1-0.10.6-0.3-0.2-0.1-0.30.00.1-0.00.2-0.4
Light reinforcement 10.20.40.9-0.80.3-0.8-0.8-0.1-0.90.50.5-0.80.50.8-1.00.1-0.1
Light reinforcement 20.20.20.6-0.40.40.20.4-0.60.2-0.6-0.70.3-0.7-0.20.3-0.80.4
Bone: marrow area0.00.00.0-0.1-0.1-0.1-0.00.2-0.1-0.0-0.0-0.0-0.0-0.20.10.10.0
Bone: maximum diameter3.46.37.5-2.2-2.6-2.6-2.72.7-2.72.62.6-2.62.62.5-2.52.4-1.6
Bone: maximum force0.00.10.3-0.5-0.4-0.2-0.10.4-0.10.0-0.1-0.2-0.10.10.0-0.20.4
Bone: maximum moment0.10.10.6-0.8-0.6-0.4-0.10.5-0.20.0-0.1-0.2-0.00.10.0-0.20.0
Mean time between licks in bursts0.50.72.91.70.11.10.7-0.20.5-0.5-0.60.9-0.6-1.00.60.21.4
Mean num. licks in bursts1.51.77.52.71.01.91.0-1.01.1-1.0-0.90.9-0.9-0.70.9-0.02.1
Cd content in liver1.21.32.40.91.31.11.1-1.51.1-1.0-1.11.1-1.1-1.11.1-1.21.1
Co content in liver0.50.61.1-0.5-0.1-0.7-0.8-0.2-0.80.70.9-0.90.91.0-0.90.6-1.0
Cu content in liver0.10.20.8-0.40.1-0.4-0.3-0.1-0.30.40.3-0.50.30.2-0.40.3-0.9
Fe content in liver0.81.03.92.00.31.40.9-0.50.8-0.8-0.90.7-0.9-0.90.80.21.3
K content in liver1.61.62.9-1.7-0.4-1.6-1.30.5-1.31.21.2-1.41.21.3-1.30.7-1.7
Mg content in liver2.93.04.1-1.9-1.1-2.0-1.81.1-1.81.81.8-1.91.81.8-1.81.3-2.0
Mn content in liver0.20.20.6-0.70.1-0.7-0.50.2-0.60.40.4-0.40.40.4-0.50.1-0.8
Na content in liver6.66.99.1-1.7-2.6-2.4-2.82.8-2.82.82.8-2.82.82.6-2.83.0-1.7
Rb content in liver1.21.42.1-1.4-1.0-1.3-1.20.9-1.31.31.2-1.21.21.1-1.11.0-1.3
Se content in liver1.82.33.4-1.8-1.3-1.8-1.51.1-1.51.51.5-1.41.51.2-1.41.3-1.9
Sr content in liver0.40.41.70.1-1.3-0.2-0.51.0-0.50.60.6-0.30.60.3-0.30.80.5
Zn content in liver0.00.10.2-0.2-0.4-0.10.20.2-0.1-0.0-0.10.4-0.1-0.50.2-0.10.0
Bone: minimum diameter0.00.00.1-0.20.3-0.10.1-0.20.0-0.2-0.2-0.0-0.2-0.00.1-0.40.0
Time in familiar zone, hab. session 11.61.52.61.10.51.31.3-0.51.4-1.1-1.31.5-1.3-1.51.4-1.01.6
Time in novel zone, hab. session 11.00.92.3-1.2-0.5-1.2-0.90.4-1.10.80.9-1.00.91.1-0.90.6-1.5
Total zone transitions, hab. session 10.50.82.01.40.61.20.8-0.00.8-0.7-0.80.8-0.8-0.70.8-0.41.3
Total locomotion distance, hab. session 10.00.10.40.60.10.3-0.10.3-0.1-0.0-0.0-0.1-0.0-0.1-0.10.30.2
Locomotion velocity, hab. session 10.10.10.90.90.40.50.00.20.0-0.1-0.1-0.0-0.1-0.1-0.10.30.5
Time in familiar zone, hab. session 23.94.05.31.61.82.12.1-1.92.3-2.1-2.32.0-2.2-2.02.0-1.91.6
Time in novel zone, hab. session 22.42.43.2-1.4-1.7-1.6-1.51.6-1.81.61.7-1.51.61.5-1.41.4-1.0
Total zone transitions, hab. session 20.10.10.40.5-0.20.0-0.30.3-0.50.30.4-0.40.30.3-0.40.50.6
Total locomotion distance, hab. session 20.30.30.80.3-0.7-0.2-0.60.8-0.70.60.6-0.50.60.3-0.60.90.4
Locomotion velocity, hab. session 20.50.71.3-0.1-0.9-0.6-0.91.0-1.10.90.9-0.90.90.6-0.91.10.1
Novel to familiar place preference ratio2.42.43.7-0.4-1.3-1.1-1.81.3-1.71.71.9-1.71.91.9-1.71.9-0.7
Novelty place preference2.22.33.4-0.4-1.2-1.1-1.71.3-1.61.71.8-1.71.81.8-1.61.8-0.8
Time in novel zone, NPP test1.81.82.8-0.2-1.1-1.0-1.51.1-1.51.51.6-1.51.61.7-1.41.6-0.6
Total zone transitions, NPP test0.10.10.80.10.90.10.3-0.60.2-0.4-0.3-0.0-0.30.00.1-0.5-0.1
Total locomotion distance, NPP test0.00.10.2-0.10.3-0.2-0.2-0.1-0.20.10.1-0.40.10.2-0.30.1-0.4
Locomotion velocity, NPP test0.20.30.6-0.40.0-0.5-0.50.2-0.60.40.5-0.70.50.6-0.70.5-0.7
Intraocular pressure0.30.32.61.0-0.50.5-0.10.3-0.00.30.30.40.2-0.40.00.41.6
Delta distance traveled before/after self-admin0.40.40.6-0.5-0.7-0.6-0.80.7-0.70.70.7-0.70.80.6-0.60.3-0.2
Delta ambulatory time before/after self-admin0.00.00.1-0.1-0.2-0.2-0.30.1-0.20.30.4-0.20.40.1-0.0-0.1-0.2
Parametrial fat weight1.12.14.8-0.1-1.4-0.9-1.61.4-1.51.71.7-1.51.71.4-1.52.2-0.1
Pavlov. Cond. lever latency0.30.40.9-0.2-0.8-0.5-0.60.8-0.60.70.7-0.60.70.7-0.61.0-0.5
Pavlov. Cond. magazine entry latency1.21.51.91.31.21.41.2-1.11.2-1.3-1.31.1-1.3-1.21.2-1.01.4
Pavlov. Cond. change in total contacts0.60.61.2-0.2-1.0-0.5-0.81.1-0.90.80.8-0.70.80.6-0.71.0-0.0
Pavlov. Cond. index score1.21.51.91.21.41.31.2-1.31.2-1.3-1.21.1-1.2-1.11.1-1.21.2
Pavlov. Cond. latency score1.21.51.81.11.31.31.2-1.21.2-1.3-1.31.1-1.3-1.11.2-1.31.2
Pavlov. Cond. lever contacts0.50.60.80.60.80.80.8-0.90.7-0.9-0.80.7-0.8-0.70.7-0.90.8
Pavlov. Cond. magazine entry number1.21.52.8-1.7-1.2-1.5-1.11.2-1.11.31.2-1.01.21.0-1.00.8-1.5
Pavlov. Cond. intertrial magazine entries0.60.72.7-1.40.4-1.2-0.6-0.1-0.70.70.7-0.80.70.7-0.8-0.1-1.6
Pavlov. Cond. lever-magazine prob. diff.1.31.62.01.21.41.31.2-1.41.2-1.3-1.31.1-1.3-1.21.1-1.31.2
Pavlov. Cond. response bias0.10.20.40.50.60.40.3-0.60.3-0.4-0.30.2-0.3-0.40.2-0.30.4
Pavlov. Cond. lever latency1.92.65.8-2.4-1.4-2.2-1.61.5-1.61.71.6-1.21.60.8-1.41.0-1.8
Pavlov. Cond. magazine entry latency0.00.00.2-0.2-0.4-0.1-0.20.3-0.10.20.2-0.20.10.2-0.10.0-0.0
Pavlov. Cond. change in total contacts0.81.12.21.50.81.41.0-0.81.1-1.0-1.00.8-1.0-0.61.0-0.81.4
Pavlov. Cond. index score0.91.22.21.50.91.41.1-1.01.1-1.1-1.10.8-1.1-0.61.0-0.81.3
Pavlov. Cond. latency score0.91.12.11.40.91.41.1-1.01.1-1.1-1.10.8-1.1-0.61.0-0.91.2
Pavlov. Cond. lever contacts2.33.16.72.61.62.31.7-1.61.8-1.8-1.71.4-1.7-1.11.6-1.12.0
Pavlov. Cond. magazine entry number0.00.00.2-0.10.5-0.2-0.1-0.4-0.20.10.1-0.10.1-0.0-0.20.0-0.2
Pavlov. Cond. intertrial magazine entries0.10.10.40.20.6-0.10.0-0.6-0.1-0.1-0.0-0.10.0-0.0-0.1-0.1-0.2
Pavlov. Cond. lever-magazine prob. diff.1.01.22.11.40.91.41.1-1.01.2-1.1-1.10.9-1.1-0.71.1-0.91.3
Pavlov. Cond. response bias1.01.43.11.80.71.71.2-0.81.2-1.2-1.21.0-1.2-0.71.1-0.71.3
Time in closed arm before self-admin0.40.40.80.10.30.60.5-0.30.1-0.8-0.80.8-0.7-0.90.8-0.90.5
Time in closed arm after self-admin3.03.04.51.02.01.51.9-2.11.7-2.1-1.91.7-1.9-1.71.7-2.10.6
Time in open arm before self-admin0.10.10.50.10.7-0.20.1-0.50.30.20.00.00.0-0.0-0.2-0.20.0
Time in open arm after self-admin1.01.12.0-0.1-1.2-0.7-1.11.2-0.91.31.2-1.21.21.3-1.11.4-0.0
Bone: periosteal estimation0.61.31.9-1.4-1.1-1.4-1.21.2-1.31.11.1-1.31.11.2-1.10.8-0.8
Bone: periosteal perimeter2.64.35.4-2.1-1.9-2.3-2.22.0-2.22.12.1-2.32.12.2-2.11.7-1.6
Bone: post-yield work0.10.10.7-0.3-0.8-0.20.10.7-0.10.00.00.1-0.0-0.10.30.3-0.3
Progressive ratio test 1 active lever presses2.02.13.1-1.0-1.3-1.3-1.61.5-1.41.51.4-1.81.31.8-1.61.7-1.1
Progressive ratio test 1 breakpoint1.61.72.6-0.9-1.0-1.2-1.41.2-1.21.31.2-1.61.11.6-1.41.5-1.1
Progressive ratio test 1 inactive lever presses3.33.65.0-1.6-1.7-1.9-2.01.8-2.01.71.7-2.21.72.2-2.22.1-1.4
Progressive ratio test 2 active lever presses1.01.12.7-0.9-1.5-0.9-1.11.6-0.91.11.0-0.80.90.8-0.81.1-0.7
Progressive ratio test 2 breakpoint0.91.02.6-0.6-1.4-0.7-1.01.6-0.81.01.0-0.90.90.8-0.81.2-0.4
Progressive ratio test 2 inactive lever presses2.83.25.8-1.3-2.2-1.4-2.02.4-1.81.82.0-1.72.01.7-1.71.8-0.4
Incentive Sensitization - Responses0.50.51.9-0.6-1.3-0.5-0.61.4-0.40.90.7-0.30.70.2-0.30.70.0
Incentive Sensitization - Breakpoint0.50.52.0-0.6-1.4-0.5-0.61.4-0.40.80.7-0.30.60.2-0.30.60.0
Sum of active levers in priming session hrs 5-61.21.11.7-1.1-1.1-1.1-1.01.1-0.61.00.8-1.30.91.3-1.20.9-1.2
Progressive ratio0.20.31.2-0.8-1.1-0.5-0.11.1-0.10.30.40.10.4-0.00.20.2-0.2
Food seeking constrained by brief footshock3.03.76.7-2.6-1.9-2.4-1.82.2-1.82.02.1-1.72.11.7-1.71.3-1.5
Seeking ratio, punishment vs. effort0.81.01.8-0.80.0-1.1-1.20.1-1.21.01.0-1.31.01.2-1.30.7-0.8
Retroperitoneal fat weight0.00.10.80.3-0.2-0.1-0.40.1-0.10.50.50.00.40.0-0.20.20.9
Reaction time number correct0.50.71.71.30.10.90.9-0.20.7-0.7-0.71.0-0.8-1.01.0-0.41.3
Reaction time mean minus median0.00.10.30.1-0.50.00.10.30.2-0.2-0.10.1-0.20.10.10.4-0.4
Reaction time mean minus median AUC0.20.20.5-0.6-0.6-0.6-0.50.4-0.30.30.4-0.50.30.6-0.50.4-0.7
Reaction time num false alarms0.91.22.0-1.4-0.6-1.2-1.20.7-1.11.01.1-1.41.11.4-1.20.6-0.9
Reaction time num false alarms AUC0.71.02.6-1.6-0.4-1.2-1.00.7-0.90.91.0-1.21.01.1-1.00.3-0.8
Reaction time trials correct on left0.50.71.71.30.10.90.9-0.20.7-0.7-0.71.0-0.8-1.01.0-0.41.3
Reaction time trials on left0.50.81.71.30.20.90.9-0.30.7-0.7-0.71.0-0.8-1.01.0-0.41.3
Reaction time mean0.00.10.4-0.20.00.00.30.20.4-0.2-0.10.2-0.1-0.00.3-0.0-0.6
Reaction time mean AUC0.10.10.4-0.20.20.10.30.00.5-0.3-0.20.3-0.3-0.10.3-0.2-0.6
Median of all reaction times0.10.10.4-0.20.30.00.30.10.5-0.2-0.10.3-0.1-0.10.3-0.2-0.7
Reaction time omissions0.00.00.20.40.50.20.0-0.30.3-0.2-0.10.1-0.1-0.2-0.0-0.10.2
Reaction time false alarm rate1.31.84.9-2.2-0.5-1.7-1.40.8-1.21.21.3-1.61.31.6-1.40.4-1.5
Reaction time premature initiation rate3.85.09.01.93.02.12.0-3.02.1-2.3-2.22.0-2.2-2.11.7-2.42.1
Reaction time premature initiations3.44.86.22.22.52.12.1-2.52.0-2.2-2.12.1-2.2-2.21.8-2.12.4
Std. dev. reaction times0.00.10.3-0.1-0.5-0.1-0.00.60.20.10.20.10.20.10.00.3-0.3
Reaction time trials completed0.50.81.71.30.20.90.9-0.30.7-0.7-0.71.0-0.8-1.01.0-0.41.3
Reaction time trials AUC0.40.61.31.10.10.80.8-0.20.6-0.6-0.71.0-0.7-0.90.9-0.41.1
Run reversals in cocaine runway, females0.10.10.60.20.10.30.3-0.00.4-0.1-0.10.4-0.2-0.50.5-0.10.8
Run reversals in cocaine runway, males0.00.00.1-0.2-0.1-0.1-0.2-0.1-0.3-0.00.0-0.20.00.1-0.20.2-0.0
Latency to leave start box in cocaine runway0.40.40.8-0.4-0.0-0.5-0.7-0.0-0.60.70.8-0.90.80.9-0.70.6-0.5
Latency to leave start box in cocaine runway, F0.20.20.6-0.6-0.1-0.5-0.60.1-0.30.50.5-0.70.50.8-0.60.1-0.2
Latency to leave start box in cocaine runway, M0.30.30.70.40.1-0.2-0.3-0.2-0.50.40.7-0.60.70.5-0.40.8-0.5
Std. dev. time between licks in bursts0.91.11.81.30.81.21.1-0.91.0-0.9-1.01.1-1.0-1.21.0-0.71.1
Total sessions with >9 infusions0.10.10.20.00.50.00.2-0.40.4-0.1-0.3-0.0-0.40.10.1-0.20.1
Short access day 1 total inactive lever presses1.41.52.5-1.3-1.2-1.3-1.31.5-1.61.31.2-1.21.21.2-1.11.1-0.6
Short access day 10 total inactive lever presses0.30.41.90.81.40.40.4-1.30.3-0.3-0.20.2-0.1-0.10.0-0.50.5
Short access day 1 total infusions0.10.20.5-0.70.2-0.7-0.20.0-0.10.40.4-0.40.30.4-0.3-0.1-0.6
Short access day 10 total infusions0.10.10.30.10.20.30.3-0.00.3-0.5-0.40.3-0.4-0.30.5-0.30.2
Short access total infusions0.00.00.3-0.50.2-0.3-0.10.0-0.10.00.0-0.0-0.0-0.00.2-0.3-0.2
Short access day 1 locomotion1.61.82.70.51.41.11.4-1.51.4-1.6-1.51.3-1.5-1.21.3-1.60.6
Short access day 10 total locomotion2.12.33.31.81.41.81.4-1.41.3-1.8-1.61.5-1.6-1.51.8-1.11.1
Short access total locomotion5.05.26.42.02.42.42.2-2.42.1-2.5-2.52.2-2.5-2.22.4-2.21.8
One hour access (0.3 mA shock)0.50.61.3-0.7-1.0-0.7-0.71.1-0.70.60.7-0.60.70.6-0.71.0-0.7
Compulsive drug intake3.83.86.61.82.61.82.1-2.52.2-1.9-1.81.9-1.8-1.91.8-2.00.9
One hour access (shock baseline)4.14.87.6-1.8-2.6-2.0-2.42.7-2.32.12.1-2.02.12.0-2.02.4-1.7
Social response proportion0.20.20.70.8-0.80.30.10.6-0.00.20.20.40.1-0.50.20.60.4
Social responses0.20.21.20.5-1.10.0-0.10.7-0.30.30.30.20.2-0.4-0.10.80.2
Social time0.50.71.41.0-0.00.71.0-0.51.0-0.6-0.61.1-0.6-1.21.2-0.40.5
Soleus weight0.41.34.0-2.0-1.3-1.6-1.01.3-1.30.90.8-0.70.80.6-0.80.3-1.2
Bone: stiffness0.10.10.20.30.50.40.1-0.40.1-0.3-0.4-0.4-0.40.50.0-0.20.5
Tibialis anterior weight1.44.96.6-2.3-2.5-2.3-2.32.6-2.42.32.2-2.02.21.9-2.02.0-1.9
Time to tail flick, vehicle, before self-admin0.20.20.5-0.7-0.6-0.6-0.40.7-0.00.60.3-0.10.40.1-0.2-0.10.0
Time to tail flick, vehicle, after self-admin0.10.10.50.20.10.20.1-0.10.50.10.00.10.0-0.10.2-0.20.7
Time to tail flick, test, before self-admin0.90.91.31.11.11.01.0-1.11.1-0.9-0.70.9-0.7-0.80.7-0.90.9
Time to tail flick, test, after self-admin0.60.70.9-0.9-0.9-0.9-0.61.0-0.80.70.9-0.90.90.9-0.80.5-0.3
Delta time to tail flick, vehicle, before/after SA0.20.20.50.70.40.60.4-0.50.6-0.3-0.20.3-0.2-0.20.30.00.5
Delta time to tail flick, test, before/after SA1.11.01.3-1.0-1.0-1.1-0.91.1-1.11.01.0-1.21.01.1-0.80.9-0.7
Tibia length0.20.51.7-0.90.7-0.20.6-0.70.6-0.5-0.60.5-0.6-0.60.7-1.3-0.3
Ambulatory time before self-admin0.10.10.4-0.3-0.20.40.20.10.1-0.6-0.40.1-0.5-0.10.00.2-0.5
Ambulatory time after self-admin0.10.10.3-0.4-0.50.1-0.10.4-0.3-0.2-0.1-0.4-0.10.3-0.20.5-0.5
Bone: tissue strength1.01.01.90.40.10.71.2-0.11.0-1.0-1.11.3-1.1-1.31.4-1.00.9
Total heroin consumption0.10.10.5-0.20.10.10.1-0.10.0-0.5-0.30.0-0.30.2-0.1-0.1-0.7
Bone: trabecular number0.10.20.6-0.50.7-0.30.2-0.60.1-0.3-0.20.3-0.2-0.40.1-0.6-0.8
Bone: trabecular spacing0.50.61.9-0.1-1.4-0.4-0.71.3-0.60.90.9-0.50.80.6-0.40.90.6
Bone: trabecular thickness1.11.42.4-0.01.50.61.2-1.61.0-1.4-1.31.1-1.3-1.21.1-1.5-0.5
Bone: trabecular tissue density0.20.20.50.7-0.10.70.5-0.00.6-0.5-0.50.4-0.5-0.30.6-0.10.6
Water consumed over 24 hours0.91.02.21.5-0.31.31.00.20.8-0.7-0.91.3-0.9-1.31.20.11.3
Number of responses in last shaping day0.20.20.40.30.40.60.5-0.40.4-0.6-0.50.2-0.6-0.30.2-0.40.6