Hub : Genes

LOC102549070

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC102549070 0.12 0.09 9.0e-03 0.08 0.1 0.13 0.08 5.0e-03 2.8e-03 5.1e-04 6.7e-03
2 NAcc gene expression LOC102549070 0.04 0.02 5.9e-06 0.03 0.04 0.03 0.03 1.2e-05 8.8e-07 1.2e-05 5.7e-06
3 pVTA gene expression LOC102549070 0.11 0.08 4.3e-04 0.05 0.05 0.07 0.07 1.1e-04 9.5e-05 5.1e-06 2.2e-06
4 Liver gene expression LOC102549070 0.3 0.12 0.0e+00 0.16 0.16 0.17 0.12 5.2e-17 7.3e-17 6.5e-19 4.4e-13
5 IL gene expression LOC102549070 0.1 0.07 6.5e-03 0.02 0.04 0.01 0.01 1.3e-01 3.4e-02 1.8e-01 1.6e-01
6 Liver intron excision ratio chr1_241834542_241840258 0.15 0.08 1.4e-12 0.1 0.11 0.09 0.1 8.1e-11 3.6e-12 7.2e-10 2.0e-11
7 Liver intron excision ratio chr1_241840301_241840632 0.07 0.05 2.4e-07 0.04 0.04 0.04 0.04 6.7e-05 1.1e-05 1.1e-05 5.6e-05
8 Brain gene expression LOC102549070 0.07 0.04 2.3e-08 0.08 0.09 0.08 0.09 8.0e-08 5.9e-09 3.5e-08 1.8e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density4.27.710.8-3.33.01.12.83.1-2.72.92.6
Area under the delay curve1.92.97.2-1.32.7-0.70.81.8-2.31.81.3
BMI with tail1.34.68.21.4-2.81.5-0.4-2.12.9-2.6-2.2
BMI without tail0.21.32.21.2-1.00.9-0.7-1.21.2-1.2-1.5
Body weight0.31.47.20.40.22.71.1-0.30.7-0.1-1.5
Weight adjusted by age0.00.00.10.30.0-0.2-0.3-0.10.1-0.3-0.0
Bone surface3.67.09.5-3.03.10.72.33.0-2.82.92.6
Bone volume3.97.810.9-3.33.30.92.53.1-2.93.02.5
Breakpoint value in progressive ratio session0.61.13.71.9-0.51.20.9-0.60.9-0.4-1.3
Number of licking bursts3.410.217.54.2-3.0-0.4-2.6-3.63.1-3.5-3.5
Context. condit. distance diff. score0.81.02.80.6-0.91.71.2-0.31.2-0.7-0.6
Locomotion velocity, session 11.51.73.61.1-1.2-1.8-1.9-1.20.6-1.4-0.6
Locomotion distance, session 10.20.20.40.5-0.7-0.3-0.5-0.50.4-0.6-0.4
Locomotion velocity, session 21.11.31.90.9-1.3-1.2-1.4-1.20.8-1.3-0.6
Locomotion distance, session 21.01.43.21.8-1.1-0.4-1.0-1.41.0-1.1-1.3
Locomotion velocity, session 30.40.42.0-0.5-0.31.40.8-0.10.4-0.1-0.5
Locomotion distance, session 30.60.63.4-0.4-0.41.80.9-0.20.40.0-0.6
Stereotopy head waving bouts, day 30.80.93.0-0.80.7-1.7-0.60.6-0.80.61.2
Stereotopy head waving duration, day 30.81.02.0-0.81.1-1.40.00.9-1.01.01.3
Locomotion velocity, session 70.20.20.8-0.00.30.90.70.2-0.00.3-0.2
Locomotion distance, session 70.60.71.3-0.61.10.81.10.8-0.71.00.4
Stereotopy head waving bouts, day 70.20.20.70.8-0.6-0.3-0.3-0.30.4-0.4-0.1
Stereotopy head waving duration, day 70.20.30.80.9-0.7-0.2-0.3-0.40.5-0.5-0.2
Locomotion velocity, session 80.20.20.80.4-0.10.70.90.20.2-0.0-0.0
Locomotion distance, session 80.91.32.71.6-1.31.10.6-0.81.4-1.0-1.0
Degree of sensitization distance0.30.30.90.21.0-0.60.10.6-0.60.50.5
Degree of sensitization stereotypy0.10.10.50.4-0.20.70.50.10.10.1-0.0
Conditioned locomotion1.82.23.6-1.41.41.11.91.6-1.21.71.2
Cocaine response after cond. corrected0.61.01.6-0.71.20.20.91.1-1.11.30.9
Cocaine response after cond. not corrected0.81.22.6-0.81.60.61.11.2-1.21.20.7
Cocaine response before conditioning0.10.10.50.20.70.1-0.20.0-0.3-0.2-0.5
Saline control response2.83.87.3-2.51.81.82.72.0-1.41.71.3
Bone: connectivity density3.25.27.1-2.72.5-0.31.52.5-2.42.62.5
Bone: cortical apparent density1.62.54.2-1.41.6-2.1-0.31.4-1.91.51.9
Bone: cortical area2.03.35.5-1.42.31.72.02.0-1.91.91.1
Bone: cortical porosity0.10.10.20.4-0.50.3-0.1-0.30.5-0.3-0.3
Bone: cortical porosity0.10.10.20.5-0.10.3-0.1-0.20.2-0.1-0.3
Bone: cortical thickness0.40.61.7-0.21.31.10.60.6-0.90.6-0.1
Bone: cortical thickness0.70.91.9-1.01.4-0.10.10.9-1.40.90.7
Bone: cortical tissue density1.42.34.5-1.21.4-2.1-0.41.3-1.71.41.8
Condit. Reinf. active minus inactive responses0.20.20.50.3-0.2-0.4-0.7-0.50.1-0.4-0.5
Condit. Reinf. active-inactive response ratio0.60.62.1-0.1-0.7-0.9-1.5-0.80.3-0.7-0.3
Condit. Reinf. active responses0.10.10.30.30.00.60.5-0.10.20.1-0.5
Condit. Reinf. inactive responses0.60.72.70.90.11.41.60.20.40.4-0.4
Incentive salience index mean0.10.20.50.2-0.10.1-0.4-0.50.1-0.3-0.7
Condit. Reinf. lever presses0.00.00.10.10.1-0.1-0.3-0.3-0.10.0-0.4
Condit. Reinf. active minus inactive responses0.20.30.60.4-0.50.0-0.6-0.70.6-0.6-0.8
Condit. Reinf. active-inactive response ratio0.50.71.11.0-0.90.0-0.7-0.90.9-1.1-0.9
Condit. Reinf. active responses0.00.00.1-0.30.20.2-0.1-0.1-0.00.2-0.3
Condit. Reinf. inactive responses0.40.71.4-0.81.10.40.60.8-0.81.20.4
Condit. Reinf. lever presses0.10.10.4-0.10.1-0.3-0.7-0.1-0.10.1-0.1
Condit. Reinf. lever reinforcers received0.00.10.30.10.0-0.0-0.5-0.30.10.0-0.4
Conditioned reinforcement - actives0.31.23.2-1.20.81.81.60.9-0.40.80.3
Conditioned reinforcement - inactives1.54.28.5-2.91.81.82.22.1-1.72.01.7
Conditioned locomotion2.03.05.9-2.01.11.62.41.8-1.11.81.5
Patch foraging indifference point 0 sec0.51.53.7-0.91.9-1.0-0.50.9-1.91.00.8
Patch foraging indifference point AUC0.20.61.1-0.61.10.30.70.7-0.90.90.4
Delay disc. indifference point, 0s delay1.21.32.80.01.41.61.71.1-0.81.00.2
Delay disc. indifference point, 16s delay3.14.48.7-2.02.9-0.91.22.3-2.62.21.9
Delay disc. indifference point, 2s delay2.42.75.4-1.22.3-1.00.61.7-2.11.91.5
Delay disc. indifference point, 24s delay2.94.68.6-2.12.9-0.11.62.4-2.72.41.8
Delay disc. indifference point, 4s delay0.60.72.1-0.11.01.41.20.6-0.40.4-0.2
Delay disc. indifference point, 8s delay1.62.75.3-1.62.3-1.9-0.51.3-2.21.31.3
Indifference point function ln k0.20.61.10.7-1.00.6-0.2-0.71.0-0.8-0.7
Indifference point function log k0.20.61.10.7-1.00.6-0.2-0.71.0-0.8-0.7
Patch foraging total patch changes 0 sec0.41.22.9-0.71.7-1.1-0.70.7-1.60.80.6
Patch foraging total patch changes 12 sec0.81.12.6-0.91.6-0.50.41.1-1.51.00.9
Patch foraging total patch changes 18 sec0.10.31.0-0.51.0-0.4-0.10.4-0.80.40.2
Patch foraging total patch changes 24 sec0.30.92.7-1.11.7-0.5-0.30.7-1.40.70.4
Patch foraging total patch changes 6 sec1.62.76.2-1.62.5-0.30.41.6-2.41.51.3
Patch foraging time to switch 0 sec0.52.14.11.1-1.8-0.0-0.8-1.61.6-2.0-1.4
Patch foraging water rate 0 sec0.52.03.4-1.21.6-0.50.61.6-1.71.91.6
Patch foraging water rate 12 sec0.41.42.8-1.41.7-0.40.21.2-1.61.21.0
Patch foraging water rate 18 sec0.10.20.5-0.70.50.20.10.4-0.40.20.2
Patch foraging water rate 24 sec1.31.93.7-1.51.90.61.31.4-1.51.50.8
Patch foraging water rate 6 sec0.30.41.0-1.00.4-0.6-0.20.5-0.60.60.7
Seeking ratio, delayed vs. immediate footshock0.91.32.81.7-1.31.20.2-0.91.4-0.8-1.0
Distance traveled before self-admin0.30.61.10.0-1.0-0.9-0.9-0.90.7-1.1-0.5
Distance traveled after self-admin0.10.20.7-0.7-0.1-0.00.80.40.20.10.5
Extensor digitorum longus weight0.41.84.71.5-1.12.21.3-0.61.5-0.5-1.2
Bone: elastic displacement1.41.88.7-0.0-0.2-2.9-1.90.0-0.6-0.01.2
Bone: elastic work1.52.05.5-1.00.5-2.3-1.01.1-1.40.92.1
Bone: endosteal estimation2.97.09.0-2.92.71.73.03.0-2.32.92.4
Bone: endosteal perimeter1.23.04.9-1.91.41.62.21.9-1.21.81.6
Epididymis fat weight0.21.14.2-0.40.62.01.80.8-0.20.70.0
Delta time in closed arm before/after self-admin1.21.22.81.7-0.6-1.5-1.5-0.90.2-0.7-0.6
Delta time in open arm before/after self-admin0.80.92.4-1.00.31.61.50.80.10.70.5
Diff in mean of infusions in LGA sessions2.13.76.82.6-2.40.2-1.0-2.02.3-1.9-1.8
Delay discount exponential model param2.23.17.41.3-2.70.6-0.8-1.92.3-1.9-1.3
Extinction: sum of active levers before priming0.30.42.71.6-0.10.00.2-0.20.3-0.1-0.4
Active lever presses in extinction session 61.41.43.41.7-0.71.81.3-0.51.2-0.5-1.1
Bone: final force0.91.52.4-0.91.51.51.41.3-1.21.10.5
Bone: final moment1.42.33.8-1.41.91.01.41.7-1.81.51.1
Food consumed during 24 hour testing period0.10.10.30.20.5-0.1-0.10.0-0.60.5-0.2
Glucose0.10.10.70.8-0.30.20.2-0.10.2-0.2-0.1
Heart weight1.72.74.5-1.61.9-1.30.01.5-2.11.91.7
Delay discount hyperbolic model param2.22.86.81.1-2.60.8-0.7-1.82.2-1.8-1.4
Intermittent access intake day 1-15 change0.00.10.5-0.70.10.40.20.2-0.2-0.20.1
Intermittent access intake escalation0.00.30.8-0.9-0.10.90.60.20.1-0.30.0
Intermittent access intake escalation 20.30.51.4-0.1-1.10.3-0.3-0.70.8-1.2-0.5
Intermitt. access day 1 inactive lever presses0.00.21.2-1.10.2-0.20.00.4-0.40.20.5
Intermitt. access day 15 inactive lever presses0.52.78.2-2.91.30.61.41.7-1.31.51.6
Intermitt. access escalation Index0.00.10.3-0.1-0.50.5-0.2-0.30.6-0.4-0.3
Intermittent access day 1 total infusions0.51.55.4-1.10.32.31.90.80.00.80.3
Intermittent access day 15 total infusions0.82.07.6-1.70.22.82.10.80.10.40.2
Intermittent access terminal intake (last 3 days)1.01.76.7-1.6-0.22.61.90.60.40.10.1
Intermittent access total infusions1.41.67.0-1.1-0.32.62.10.50.50.1-0.1
Intermittent access day 1 locomotion0.81.57.1-0.4-0.52.71.80.20.80.3-0.2
Intermittent access day 15 total locomotion0.52.15.3-1.80.22.32.31.2-0.20.90.9
Intermittent access total locomotion1.82.18.6-1.2-0.62.92.50.50.70.30.1
Intermittent access standard deviation0.10.31.1-0.9-0.01.10.60.20.0-0.2-0.1
Left kidney weight0.10.83.00.9-0.11.70.3-0.50.8-0.4-1.3
Right kidney weight0.21.54.61.1-0.32.20.4-1.00.9-0.7-1.9
Cocaine induced anxiety0.00.10.2-0.30.40.0-0.00.2-0.30.10.1
Post-drug Anxiety0.80.91.6-0.51.2-1.2-0.10.9-1.30.91.1
Baseline Anxiety0.71.11.9-0.41.0-1.30.31.1-1.31.21.4
Tail length0.94.611.2-1.43.31.41.82.1-2.42.70.8
Length with tail1.35.912.5-1.63.52.62.62.2-2.22.90.5
Length without tail0.63.212.3-0.81.23.53.01.0-0.01.1-0.6
Times rat made contact with spout0.20.31.00.5-0.11.00.5-0.30.3-0.3-0.7
Lifetime Intake1.11.46.1-1.0-0.32.51.90.40.50.1-0.1
Liver weight, left0.30.51.2-0.70.90.50.20.7-0.81.10.4
Liver weight, right0.20.31.40.50.01.20.70.00.40.2-0.4
Locomotor activity0.91.42.00.9-1.3-0.3-1.4-1.41.1-1.3-1.3
Locomotor testing distance1.63.95.51.8-2.0-0.7-2.3-2.31.9-2.2-2.1
Locomotor testing rearing1.03.77.62.7-2.00.2-1.2-2.02.3-1.7-2.0
Locomotion in novel chamber0.20.30.90.0-0.90.90.60.00.7-0.10.2
Locomotion in novel chamber post-restriction0.61.93.31.4-1.41.80.4-1.11.8-1.2-1.4
Fecal boli incidents, locomotor time 10.20.61.9-1.20.01.40.90.4-0.10.10.3
Change in fecal boli incidents, locomotor task0.60.71.71.3-0.70.1-0.6-0.90.9-0.7-0.9
Time >=10cm from walls, locomotor time 10.70.93.4-0.60.31.81.60.40.20.4-0.2
Bouts of movement, locomotor time 11.01.32.61.1-0.91.3-0.2-1.21.1-1.1-1.6
Total resting periods, locomotor time 10.80.93.80.3-0.31.90.5-0.60.6-0.5-1.3
Rest time, locomotor task time 10.30.50.90.8-0.50.90.0-0.60.7-0.8-0.7
Distance moved, locomotor task time 10.10.20.50.3-0.2-0.7-0.7-0.50.1-0.0-0.4
Vertical activity count, locomotor time 10.10.41.10.3-0.6-0.8-1.1-0.70.4-0.3-0.4
Time >=10cm from walls, locomotor time 20.10.30.7-0.30.80.10.50.5-0.50.90.3
Bouts of movement, locomotor time 20.10.20.30.40.2-0.6-0.5-0.30.1-0.6-0.6
Total resting periods, locomotor time 20.10.20.50.60.2-0.4-0.5-0.30.1-0.6-0.7
Rest time, locomotor task time 21.01.73.41.7-0.81.80.4-1.01.3-1.2-1.6
Distance moved, locomotor task time 20.40.51.90.1-0.4-1.4-1.2-0.50.1-0.0-0.0
Vertical activity count, locomotor time 20.40.94.10.0-0.1-2.0-1.8-0.3-0.2-0.10.4
Light reinforcement 10.31.42.7-1.01.3-1.6-0.80.8-1.41.11.1
Light reinforcement 21.12.58.1-0.91.3-2.9-1.40.9-1.70.91.6
Bone: marrow area3.07.39.4-3.02.71.83.13.1-2.42.92.5
Bone: maximum diameter3.67.312.1-2.82.62.43.53.0-2.22.72.2
Bone: maximum force2.14.26.2-2.02.51.11.92.3-2.32.21.8
Bone: maximum moment2.95.68.7-2.42.90.61.72.7-2.82.52.3
Mean time between licks in bursts0.31.74.41.5-0.9-2.1-2.1-1.00.4-0.5-0.2
Mean num. licks in bursts4.010.816.6-4.13.30.72.93.8-3.33.53.5
Cd content in liver1.41.55.4-0.30.9-2.3-1.50.4-1.40.71.0
Co content in liver0.40.51.9-1.0-0.2-1.4-0.9-0.1-0.10.10.6
Cu content in liver0.60.73.1-0.40.0-1.5-1.8-0.5-0.2-0.4-0.1
Fe content in liver1.62.03.60.7-1.5-0.6-1.9-1.71.2-1.7-1.4
K content in liver0.90.91.51.2-1.20.6-0.0-1.01.2-0.9-1.0
Mg content in liver0.60.71.30.6-1.10.4-0.2-0.91.1-0.9-0.9
Mn content in liver3.33.75.22.3-2.20.2-1.3-2.22.1-2.1-2.0
Na content in liver1.71.92.81.3-1.70.5-0.6-1.51.5-1.6-1.5
Rb content in liver0.50.61.61.3-0.50.80.3-0.60.8-0.6-0.9
Se content in liver14.316.927.84.9-3.7-3.2-5.3-4.63.1-4.0-3.5
Sr content in liver0.80.72.0-1.2-0.4-1.4-1.2-0.2-0.0-0.40.5
Zn content in liver1.72.03.61.5-1.4-1.3-1.9-1.61.0-1.2-1.1
Bone: minimum diameter2.14.06.3-1.92.02.02.52.2-1.72.11.5
Time in familiar zone, hab. session 10.10.10.40.60.20.50.40.3-0.10.20.1
Time in novel zone, hab. session 11.31.52.40.7-1.3-1.1-1.5-1.51.1-1.3-1.0
Total zone transitions, hab. session 10.30.41.00.7-0.51.00.6-0.40.6-0.3-0.7
Total locomotion distance, hab. session 10.40.51.00.3-0.80.8-0.2-0.80.7-1.0-1.0
Locomotion velocity, hab. session 10.30.51.2-0.1-0.71.10.1-0.60.6-0.8-0.9
Time in familiar zone, hab. session 20.91.01.8-0.31.3-1.1-0.01.0-1.41.01.2
Time in novel zone, hab. session 20.20.30.6-0.2-0.8-0.0-0.5-0.60.7-0.5-0.4
Total zone transitions, hab. session 20.10.20.80.9-0.1-0.0-0.2-0.40.1-0.1-0.5
Total locomotion distance, hab. session 20.40.50.80.8-0.6-0.4-0.9-0.90.4-0.7-0.8
Locomotion velocity, hab. session 20.60.81.11.1-0.8-0.1-0.8-1.10.7-1.0-1.1
Novel to familiar place preference ratio0.40.51.00.6-0.80.8-0.1-0.61.0-0.8-0.8
Novelty place preference0.30.40.70.6-0.70.8-0.0-0.50.9-0.6-0.6
Time in novel zone, NPP test0.60.81.20.9-1.00.7-0.4-0.81.1-0.9-0.9
Total zone transitions, NPP test0.10.10.20.50.2-0.1-0.2-0.2-0.20.2-0.4
Total locomotion distance, NPP test0.10.20.7-0.30.1-0.8-0.8-0.2-0.40.0-0.0
Locomotion velocity, NPP test0.10.10.4-0.20.1-0.5-0.6-0.2-0.3-0.0-0.2
Intraocular pressure0.91.52.4-0.91.5-1.2-0.41.1-1.61.51.3
Delta distance traveled before/after self-admin0.91.03.4-0.60.60.91.81.1-0.21.00.8
Delta ambulatory time before/after self-admin1.52.66.2-1.51.31.12.51.8-0.81.81.5
Parametrial fat weight0.61.43.61.9-0.50.7-0.4-1.30.9-0.8-1.9
Pavlov. Cond. lever latency0.00.00.1-0.2-0.0-0.20.20.20.00.20.3
Pavlov. Cond. magazine entry latency0.30.40.7-0.40.7-0.8-0.80.2-0.90.40.3
Pavlov. Cond. change in total contacts0.30.31.30.40.0-0.9-1.1-0.4-0.4-0.1-0.2
Pavlov. Cond. index score0.10.20.7-0.00.4-0.4-0.8-0.2-0.4-0.0-0.2
Pavlov. Cond. latency score0.10.10.40.00.4-0.1-0.6-0.2-0.4-0.0-0.3
Pavlov. Cond. lever contacts0.20.20.70.2-0.0-0.4-0.8-0.5-0.0-0.4-0.4
Pavlov. Cond. magazine entry number0.60.71.60.6-0.81.31.1-0.31.1-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.60.82.0-1.20.81.11.40.7-0.50.40.2
Pavlov. Cond. lever-magazine prob. diff.0.20.21.00.20.2-0.5-1.0-0.4-0.3-0.2-0.3
Pavlov. Cond. response bias0.40.51.7-0.10.4-1.3-1.3-0.2-0.70.00.2
Pavlov. Cond. lever latency1.92.64.41.5-2.11.30.3-1.52.1-1.7-1.6
Pavlov. Cond. magazine entry latency0.40.62.10.90.4-1.5-1.1-0.2-0.50.20.0
Pavlov. Cond. change in total contacts0.20.51.4-0.41.2-0.40.10.7-1.00.90.5
Pavlov. Cond. index score0.50.91.9-0.31.4-0.9-0.40.7-1.31.10.7
Pavlov. Cond. latency score0.61.02.1-0.51.5-0.7-0.20.9-1.31.20.8
Pavlov. Cond. lever contacts1.72.54.2-1.52.0-1.2-0.11.5-2.01.81.6
Pavlov. Cond. magazine entry number0.20.30.8-0.6-0.40.90.80.10.5-0.30.0
Pavlov. Cond. intertrial magazine entries0.81.63.11.0-1.11.4-0.2-1.31.5-1.4-1.7
Pavlov. Cond. lever-magazine prob. diff.0.50.71.50.01.2-1.1-0.60.5-1.10.90.6
Pavlov. Cond. response bias1.11.52.7-0.51.6-1.5-0.80.9-1.61.21.0
Time in closed arm before self-admin1.01.72.70.7-1.50.6-1.0-1.41.6-1.6-1.4
Time in closed arm after self-admin1.41.63.71.3-0.8-1.5-1.9-1.40.7-1.2-1.1
Time in open arm before self-admin0.40.52.10.30.1-1.5-0.90.0-0.60.10.5
Time in open arm after self-admin0.50.61.6-0.40.31.31.20.6-0.20.80.4
Bone: periosteal estimation3.48.210.5-2.93.22.13.23.2-2.73.12.4
Bone: periosteal perimeter1.22.45.9-1.41.32.42.31.5-0.91.30.7
Bone: post-yield work0.91.53.4-0.91.91.01.41.2-1.31.40.4
Progressive ratio test 1 active lever presses2.13.78.0-2.31.22.12.82.0-1.01.81.5
Progressive ratio test 1 breakpoint1.93.27.1-2.11.12.02.71.8-0.91.61.4
Progressive ratio test 1 inactive lever presses1.53.86.9-2.62.00.82.22.1-1.72.11.6
Progressive ratio test 2 active lever presses1.72.58.4-1.80.12.92.60.90.20.50.3
Progressive ratio test 2 breakpoint2.12.78.2-1.90.32.92.81.10.00.70.5
Progressive ratio test 2 inactive lever presses0.51.45.2-1.5-0.32.31.90.50.40.10.1
Incentive Sensitization - Responses0.41.15.0-0.4-0.62.21.4-0.10.9-0.3-0.7
Incentive Sensitization - Breakpoint0.51.15.0-0.8-0.32.21.60.20.6-0.0-0.4
Sum of active levers in priming session hrs 5-61.00.93.41.8-0.5-0.8-1.1-0.80.5-0.5-0.6
Progressive ratio0.00.10.60.8-0.0-0.0-0.1-0.20.1-0.1-0.4
Food seeking constrained by brief footshock1.72.13.40.8-1.70.9-0.3-1.61.9-1.8-1.8
Seeking ratio, punishment vs. effort0.40.91.60.3-1.10.1-0.9-1.21.2-1.2-1.1
Retroperitoneal fat weight0.20.71.61.3-0.70.7-0.0-0.81.0-0.6-1.2
Reaction time number correct0.93.16.7-2.62.1-0.80.21.8-2.01.51.8
Reaction time mean minus median0.10.41.9-0.30.1-1.4-0.60.1-0.30.30.6
Reaction time mean minus median AUC0.11.03.1-1.30.5-1.8-0.60.4-0.80.71.0
Reaction time num false alarms1.11.83.31.8-1.20.8-0.3-1.41.4-1.5-1.7
Reaction time num false alarms AUC0.92.14.82.2-1.20.5-0.8-1.61.3-1.6-1.8
Reaction time trials correct on left0.93.16.7-2.62.1-0.80.21.8-2.01.51.8
Reaction time trials on left0.93.06.7-2.62.1-0.80.21.8-2.01.41.8
Reaction time mean0.40.91.71.3-1.1-1.0-1.0-1.00.8-0.7-0.5
Reaction time mean AUC0.40.91.61.1-1.0-1.3-1.1-0.90.7-0.7-0.3
Median of all reaction times0.81.32.81.7-1.3-0.9-1.0-1.21.0-0.9-0.7
Reaction time omissions0.50.83.2-0.2-0.4-1.8-1.5-0.60.1-0.60.0
Reaction time false alarm rate3.54.99.83.1-2.21.0-0.6-2.42.4-2.2-2.6
Reaction time premature initiation rate0.71.04.4-0.8-0.32.11.4-0.10.6-0.3-0.8
Reaction time premature initiations0.61.85.7-2.41.21.51.51.1-0.80.80.4
Std. dev. reaction times0.20.63.00.5-0.3-1.7-1.2-0.50.1-0.20.1
Reaction time trials completed0.93.06.7-2.62.1-0.80.21.8-2.01.41.8
Reaction time trials AUC0.82.85.8-2.42.1-1.00.01.7-1.91.41.8
Run reversals in cocaine runway, females0.30.40.6-0.80.5-0.80.10.6-0.60.30.8
Run reversals in cocaine runway, males1.71.93.01.3-1.30.8-1.0-1.61.4-1.7-1.7
Latency to leave start box in cocaine runway0.50.71.60.9-1.20.9-0.1-0.71.2-0.7-0.5
Latency to leave start box in cocaine runway, F1.92.44.11.7-2.00.6-0.9-1.71.9-1.6-1.4
Latency to leave start box in cocaine runway, M0.10.10.5-0.10.10.70.50.3-0.10.40.2
Std. dev. time between licks in bursts1.32.58.61.2-0.7-2.9-2.8-1.20.3-0.6-0.2
Total sessions with >9 infusions0.40.51.6-0.10.61.31.20.6-0.20.70.1
Short access day 1 total inactive lever presses0.71.43.9-1.70.31.82.01.0-0.20.50.6
Short access day 10 total inactive lever presses0.10.71.8-0.70.91.31.20.6-0.50.6-0.1
Short access day 1 total infusions0.30.73.3-0.10.01.81.30.40.30.3-0.1
Short access day 10 total infusions0.40.61.9-1.40.50.70.80.8-0.50.50.6
Short access total infusions0.81.12.7-1.10.71.61.61.0-0.40.80.6
Short access day 1 locomotion0.20.41.50.1-0.51.20.7-0.10.6-0.4-0.3
Short access day 10 total locomotion0.31.32.30.6-1.51.40.5-0.91.4-1.4-0.9
Short access total locomotion0.40.61.50.3-1.01.20.5-0.51.0-0.7-0.5
One hour access (0.3 mA shock)2.73.25.4-2.31.51.62.21.9-1.31.61.5
Compulsive drug intake0.30.51.0-0.01.00.30.70.8-0.70.90.6
One hour access (shock baseline)0.20.41.2-1.0-0.61.10.3-0.30.6-0.6-0.4
Social response proportion0.20.20.7-0.3-0.80.40.30.00.6-0.20.2
Social responses0.00.10.2-0.5-0.10.1-0.10.20.10.10.3
Social time0.10.10.5-0.20.4-0.4-0.7-0.1-0.2-0.1-0.1
Soleus weight0.20.51.0-0.10.60.10.71.0-0.51.01.0
Bone: stiffness0.81.53.2-0.21.51.81.71.2-1.01.10.3
Tibialis anterior weight0.62.09.90.4-0.53.12.10.21.0-0.1-0.6
Time to tail flick, vehicle, before self-admin0.10.10.3-0.6-0.1-0.5-0.40.2-0.20.00.6
Time to tail flick, vehicle, after self-admin0.20.30.80.80.30.80.4-0.30.0-0.0-0.9
Time to tail flick, test, before self-admin0.40.52.6-1.60.4-0.20.20.6-0.50.30.8
Time to tail flick, test, after self-admin1.31.44.7-2.21.2-0.80.11.0-1.30.71.1
Delta time to tail flick, vehicle, before/after SA1.11.24.80.70.12.21.5-0.30.5-0.2-1.3
Delta time to tail flick, test, before/after SA0.00.00.1-0.3-0.00.30.0-0.1-0.0-0.2-0.2
Tibia length0.71.83.3-0.91.81.51.71.5-1.41.10.6
Ambulatory time before self-admin0.41.21.90.6-1.3-1.1-1.3-1.20.9-1.4-0.7
Ambulatory time after self-admin0.30.51.3-0.8-0.70.71.10.10.8-0.20.2
Bone: tissue strength0.20.20.4-0.40.3-0.6-0.40.2-0.50.40.4
Total heroin consumption1.11.33.81.1-0.71.91.0-0.71.1-0.5-1.4
Bone: trabecular number2.44.66.3-2.42.50.41.92.4-2.32.42.1
Bone: trabecular spacing1.01.52.61.6-1.10.0-1.0-1.41.2-1.1-1.5
Bone: trabecular thickness3.24.48.6-2.92.40.31.62.3-2.22.11.9
Bone: trabecular tissue density0.50.92.9-0.80.41.41.70.9-0.00.60.5
Water consumed over 24 hours0.50.92.61.6-0.60.8-0.2-0.90.9-0.7-1.3
Number of responses in last shaping day1.01.32.0-1.41.00.61.21.4-0.91.21.2