Hub : Genes

LOC102549070

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression LOC102549070 0.12 0.09 9.0e-03 0.08 0.1 0.13 0.08 5.0e-03 2.8e-03 5.1e-04 6.8e-03
2 NAcc gene expression LOC102549070 0.04 0.02 5.9e-06 0.03 0.04 0.03 0.03 1.2e-05 8.8e-07 1.2e-05 6.1e-06
3 pVTA gene expression LOC102549070 0.11 0.08 4.3e-04 0.05 0.05 0.07 0.07 1.1e-04 9.5e-05 4.8e-06 2.3e-06
4 Liver gene expression LOC102549070 0.3 0.12 0.0e+00 0.16 0.16 0.17 0.12 5.2e-17 7.3e-17 6.5e-19 4.2e-13
5 IL gene expression LOC102549070 0.1 0.07 6.5e-03 0.02 0.04 0.01 0.01 1.3e-01 3.4e-02 1.8e-01 1.6e-01
6 Liver intron excision ratio chr1_241834542_241840258 0.15 0.08 1.4e-12 0.1 0.11 0.09 0.1 8.1e-11 3.6e-12 6.5e-10 1.9e-11
7 Liver intron excision ratio chr1_241840301_241840632 0.07 0.05 2.4e-07 0.04 0.04 0.04 0.04 6.7e-05 1.1e-05 1.1e-05 5.3e-05
8 Brain gene expression LOC102549070 0.07 0.04 2.3e-08 0.08 0.09 0.08 0.09 8.0e-08 5.9e-09 3.5e-08 1.9e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density4.47.710.83.33.01.1-2.83.1-2.7-2.92.6
Area under the delay curve2.52.97.21.32.7-0.7-0.81.8-2.3-1.81.3
BMI with tail1.34.68.2-1.4-2.81.50.4-2.12.92.6-2.2
BMI without tail0.41.32.2-1.2-1.00.90.7-1.21.21.2-1.5
Body weight0.31.47.2-0.40.22.7-1.1-0.30.70.1-1.5
Weight adjusted by age0.00.00.1-0.30.0-0.20.3-0.10.10.3-0.0
Bone surface3.97.09.53.03.10.7-2.33.0-2.8-2.92.6
Bone volume4.47.810.93.33.30.9-2.53.1-2.9-3.02.5
Breakpoint value in progressive ratio session1.01.13.7-1.9-0.51.2-0.9-0.60.90.4-1.3
Number of licking bursts6.310.217.5-4.2-3.0-0.42.6-3.63.13.5-3.5
Context. condit. distance diff. score0.81.02.8-0.6-0.91.7-1.2-0.31.20.7-0.6
Locomotion velocity, session 11.61.73.6-1.1-1.2-1.81.9-1.20.61.4-0.6
Locomotion distance, session 10.20.20.4-0.5-0.7-0.30.5-0.50.40.6-0.4
Locomotion velocity, session 21.11.31.9-0.9-1.3-1.21.4-1.20.81.3-0.6
Locomotion distance, session 21.01.43.2-1.8-1.1-0.41.0-1.41.01.1-1.3
Locomotion velocity, session 30.40.42.00.5-0.31.4-0.8-0.10.40.1-0.5
Locomotion distance, session 30.60.63.40.4-0.41.8-0.9-0.20.4-0.0-0.6
Stereotopy head waving bouts, day 30.80.93.00.80.7-1.70.60.6-0.8-0.61.2
Stereotopy head waving duration, day 30.91.02.00.81.1-1.4-0.00.9-1.0-1.01.3
Locomotion velocity, session 70.20.20.80.00.30.9-0.70.2-0.0-0.3-0.2
Locomotion distance, session 70.60.71.30.61.10.8-1.10.8-0.7-1.00.4
Stereotopy head waving bouts, day 70.20.20.7-0.8-0.6-0.30.3-0.30.40.4-0.1
Stereotopy head waving duration, day 70.20.30.8-0.9-0.7-0.20.3-0.40.50.5-0.2
Locomotion velocity, session 80.20.20.8-0.4-0.10.7-0.90.20.20.0-0.0
Locomotion distance, session 80.91.32.7-1.6-1.31.1-0.6-0.81.41.0-1.0
Degree of sensitization distance0.30.30.9-0.21.0-0.6-0.10.6-0.6-0.50.5
Degree of sensitization stereotypy0.10.10.5-0.4-0.20.7-0.50.10.1-0.1-0.0
Conditioned locomotion1.92.23.61.41.41.1-1.91.6-1.2-1.71.2
Cocaine response after cond. corrected0.81.01.60.71.20.2-0.91.1-1.1-1.30.9
Cocaine response after cond. not corrected1.01.22.60.81.60.6-1.11.2-1.2-1.20.7
Cocaine response before conditioning0.10.10.5-0.20.70.10.20.0-0.30.2-0.5
Saline control response2.93.87.32.51.81.8-2.72.0-1.4-1.71.3
Bone: connectivity density3.35.27.12.72.5-0.3-1.52.5-2.4-2.62.5
Bone: cortical apparent density1.82.54.21.41.6-2.10.31.4-1.9-1.51.9
Bone: cortical area2.23.35.51.42.31.7-2.02.0-1.9-1.91.1
Bone: cortical porosity0.10.10.2-0.4-0.50.30.1-0.30.50.3-0.3
Bone: cortical porosity0.10.10.2-0.5-0.10.30.1-0.20.20.1-0.3
Bone: cortical thickness0.40.61.70.21.31.1-0.60.6-0.9-0.6-0.1
Bone: cortical thickness0.70.91.91.01.4-0.1-0.10.9-1.4-0.90.7
Bone: cortical tissue density1.72.34.51.21.4-2.10.41.3-1.7-1.41.8
Condit. Reinf. active minus inactive responses0.20.20.5-0.3-0.2-0.40.7-0.50.10.4-0.5
Condit. Reinf. active-inactive response ratio0.60.62.10.1-0.7-0.91.5-0.80.30.7-0.3
Condit. Reinf. active responses0.10.10.3-0.30.00.6-0.5-0.10.2-0.1-0.5
Condit. Reinf. inactive responses0.60.72.7-0.90.11.4-1.60.20.4-0.4-0.4
Incentive salience index mean0.10.20.5-0.2-0.10.10.4-0.50.10.3-0.7
Condit. Reinf. lever presses0.00.00.1-0.10.1-0.10.3-0.3-0.1-0.0-0.4
Condit. Reinf. active minus inactive responses0.30.30.6-0.4-0.50.00.6-0.70.60.6-0.8
Condit. Reinf. active-inactive response ratio0.60.71.1-1.0-0.90.00.7-0.90.91.1-0.9
Condit. Reinf. active responses0.00.00.10.30.20.20.1-0.1-0.0-0.2-0.3
Condit. Reinf. inactive responses0.50.71.40.81.10.4-0.60.8-0.8-1.20.4
Condit. Reinf. lever presses0.10.10.40.10.1-0.30.7-0.1-0.1-0.1-0.1
Condit. Reinf. lever reinforcers received0.10.10.3-0.10.0-0.00.5-0.30.1-0.0-0.4
Conditioned reinforcement - actives0.71.23.21.20.81.8-1.60.9-0.4-0.80.3
Conditioned reinforcement - inactives2.94.28.52.91.81.8-2.22.1-1.7-2.01.7
Conditioned locomotion2.33.05.92.01.11.6-2.41.8-1.1-1.81.5
Patch foraging indifference point 0 sec0.81.53.70.91.9-1.00.50.9-1.9-1.00.8
Patch foraging indifference point AUC0.40.61.10.61.10.3-0.70.7-0.9-0.90.4
Delay disc. indifference point, 0s delay1.21.32.8-0.01.41.6-1.71.1-0.8-1.00.2
Delay disc. indifference point, 16s delay4.04.48.72.02.9-0.9-1.22.3-2.6-2.21.9
Delay disc. indifference point, 2s delay2.42.75.41.22.3-1.0-0.61.7-2.1-1.91.5
Delay disc. indifference point, 24s delay4.14.68.62.12.9-0.1-1.62.4-2.7-2.41.8
Delay disc. indifference point, 4s delay0.60.72.10.11.01.4-1.20.6-0.4-0.4-0.2
Delay disc. indifference point, 8s delay2.32.75.31.62.3-1.90.51.3-2.2-1.31.3
Indifference point function ln k0.30.61.1-0.7-1.00.60.2-0.71.00.8-0.7
Indifference point function log k0.30.61.1-0.7-1.00.60.2-0.71.00.8-0.7
Patch foraging total patch changes 0 sec0.61.22.90.71.7-1.10.70.7-1.6-0.80.6
Patch foraging total patch changes 12 sec0.91.12.60.91.6-0.5-0.41.1-1.5-1.00.9
Patch foraging total patch changes 18 sec0.20.31.00.51.0-0.40.10.4-0.8-0.40.2
Patch foraging total patch changes 24 sec0.50.92.71.11.7-0.50.30.7-1.4-0.70.4
Patch foraging total patch changes 6 sec1.82.76.21.62.5-0.3-0.41.6-2.4-1.51.3
Patch foraging time to switch 0 sec1.02.14.1-1.1-1.8-0.00.8-1.61.62.0-1.4
Patch foraging water rate 0 sec1.02.03.41.21.6-0.5-0.61.6-1.7-1.91.6
Patch foraging water rate 12 sec0.71.42.81.41.7-0.4-0.21.2-1.6-1.21.0
Patch foraging water rate 18 sec0.10.20.50.70.50.2-0.10.4-0.4-0.20.2
Patch foraging water rate 24 sec1.41.93.71.51.90.6-1.31.4-1.5-1.50.8
Patch foraging water rate 6 sec0.30.41.01.00.4-0.60.20.5-0.6-0.60.7
Seeking ratio, delayed vs. immediate footshock1.11.32.8-1.7-1.31.2-0.2-0.91.40.8-1.0
Distance traveled before self-admin0.50.61.1-0.0-1.0-0.90.9-0.90.71.1-0.5
Distance traveled after self-admin0.20.20.70.7-0.1-0.0-0.80.40.2-0.10.5
Extensor digitorum longus weight0.41.84.7-1.5-1.12.2-1.3-0.61.50.5-1.2
Bone: elastic displacement1.51.88.70.0-0.2-2.91.90.0-0.60.01.2
Bone: elastic work1.52.05.51.00.5-2.31.01.1-1.4-0.92.1
Bone: endosteal estimation3.27.09.02.92.71.7-3.03.0-2.3-2.92.4
Bone: endosteal perimeter1.43.04.91.91.41.6-2.21.9-1.2-1.81.6
Epididymis fat weight0.31.14.20.40.62.0-1.80.8-0.2-0.70.0
Delta time in closed arm before/after self-admin1.21.22.8-1.7-0.6-1.51.5-0.90.20.7-0.6
Delta time in open arm before/after self-admin0.90.92.41.00.31.6-1.50.80.1-0.70.5
Diff in mean of infusions in LGA sessions3.13.76.8-2.6-2.40.21.0-2.02.31.9-1.8
Delay discount exponential model param2.73.17.4-1.3-2.70.60.8-1.92.31.9-1.3
Extinction: sum of active levers before priming0.30.42.7-1.6-0.10.0-0.2-0.20.30.1-0.4
Active lever presses in extinction session 61.41.43.4-1.7-0.71.8-1.3-0.51.20.5-1.1
Bone: final force0.91.52.40.91.51.5-1.41.3-1.2-1.10.5
Bone: final moment1.42.33.81.41.91.0-1.41.7-1.8-1.51.1
Food consumed during 24 hour testing period0.10.10.3-0.20.5-0.10.10.0-0.6-0.5-0.2
Glucose0.10.10.7-0.8-0.30.2-0.2-0.10.20.2-0.1
Heart weight1.72.74.51.61.9-1.3-0.01.5-2.1-1.91.7
Delay discount hyperbolic model param2.52.86.8-1.1-2.60.80.7-1.82.21.8-1.4
Intermittent access intake day 1-15 change0.10.10.50.70.10.4-0.20.2-0.20.20.1
Intermittent access intake escalation0.10.30.80.9-0.10.9-0.60.20.10.30.0
Intermittent access intake escalation 20.50.51.40.1-1.10.30.3-0.70.81.2-0.5
Intermitt. access day 1 inactive lever presses0.10.21.21.10.2-0.2-0.00.4-0.4-0.20.5
Intermitt. access day 15 inactive lever presses1.32.78.22.91.30.6-1.41.7-1.3-1.51.6
Intermitt. access escalation Index0.10.10.30.1-0.50.50.2-0.30.60.4-0.3
Intermittent access day 1 total infusions0.91.55.41.10.32.3-1.90.80.0-0.80.3
Intermittent access day 15 total infusions1.32.07.61.70.22.8-2.10.80.1-0.40.2
Intermittent access terminal intake (last 3 days)1.31.76.71.6-0.22.6-1.90.60.4-0.10.1
Intermittent access total infusions1.41.67.01.1-0.32.6-2.10.50.5-0.1-0.1
Intermittent access day 1 locomotion1.21.57.10.4-0.52.7-1.80.20.8-0.3-0.2
Intermittent access day 15 total locomotion1.22.15.31.80.22.3-2.31.2-0.2-0.90.9
Intermittent access total locomotion1.82.18.61.2-0.62.9-2.50.50.7-0.30.1
Intermittent access standard deviation0.10.31.10.9-0.01.1-0.60.20.00.2-0.1
Left kidney weight0.20.83.0-0.9-0.11.7-0.3-0.50.80.4-1.3
Right kidney weight0.31.54.6-1.1-0.32.2-0.4-1.00.90.7-1.9
Cocaine induced anxiety0.00.10.20.30.40.00.00.2-0.3-0.10.1
Post-drug Anxiety0.90.91.60.51.2-1.20.10.9-1.3-0.91.1
Baseline Anxiety1.01.11.90.41.0-1.3-0.31.1-1.3-1.21.4
Tail length1.24.611.21.43.31.4-1.82.1-2.4-2.70.8
Length with tail1.45.912.51.63.52.6-2.62.2-2.2-2.90.5
Length without tail1.03.212.30.81.23.5-3.01.0-0.0-1.1-0.6
Times rat made contact with spout0.20.31.0-0.5-0.11.0-0.5-0.30.30.3-0.7
Lifetime Intake1.11.46.11.0-0.32.5-1.90.40.5-0.1-0.1
Liver weight, left0.30.51.20.70.90.5-0.20.7-0.8-1.10.4
Liver weight, right0.20.31.4-0.50.01.2-0.70.00.4-0.2-0.4
Locomotor activity0.91.42.0-0.9-1.3-0.31.4-1.41.11.3-1.3
Locomotor testing distance2.23.95.5-1.8-2.0-0.72.3-2.31.92.2-2.1
Locomotor testing rearing1.83.77.5-2.7-2.00.21.2-2.02.31.7-2.0
Locomotion in novel chamber0.20.30.9-0.0-0.90.9-0.60.00.70.10.2
Locomotion in novel chamber post-restriction1.11.93.3-1.4-1.41.8-0.4-1.11.81.2-1.4
Fecal boli incidents, locomotor time 10.40.61.91.20.01.4-0.90.4-0.1-0.10.3
Change in fecal boli incidents, locomotor task0.70.71.7-1.3-0.70.10.6-0.90.90.7-0.9
Time >=10cm from walls, locomotor time 10.80.93.40.60.31.8-1.60.40.2-0.4-0.2
Bouts of movement, locomotor time 11.11.32.6-1.1-0.91.30.2-1.21.11.1-1.6
Total resting periods, locomotor time 10.80.93.8-0.3-0.31.9-0.5-0.60.60.5-1.3
Rest time, locomotor task time 10.40.50.9-0.8-0.50.9-0.0-0.60.70.8-0.7
Distance moved, locomotor task time 10.10.20.5-0.3-0.2-0.70.7-0.50.10.0-0.4
Vertical activity count, locomotor time 10.20.41.1-0.3-0.6-0.81.1-0.70.40.3-0.4
Time >=10cm from walls, locomotor time 20.20.30.70.30.80.1-0.50.5-0.5-0.90.3
Bouts of movement, locomotor time 20.10.20.3-0.40.2-0.60.5-0.30.10.6-0.6
Total resting periods, locomotor time 20.10.20.5-0.60.2-0.40.5-0.30.10.6-0.7
Rest time, locomotor task time 21.41.73.4-1.7-0.81.8-0.4-1.01.31.2-1.6
Distance moved, locomotor task time 20.40.51.9-0.1-0.4-1.41.2-0.50.10.0-0.0
Vertical activity count, locomotor time 20.70.94.1-0.0-0.1-2.01.8-0.3-0.20.10.4
Light reinforcement 10.61.42.71.01.3-1.60.80.8-1.4-1.11.1
Light reinforcement 21.62.58.10.91.3-2.91.40.9-1.7-0.91.6
Bone: marrow area3.47.39.43.02.71.8-3.13.1-2.4-2.92.5
Bone: maximum diameter3.97.312.12.82.62.4-3.53.0-2.2-2.72.2
Bone: maximum force2.34.26.22.02.51.1-1.92.3-2.3-2.21.8
Bone: maximum moment3.25.68.72.42.90.6-1.72.7-2.8-2.52.3
Mean time between licks in bursts0.71.74.4-1.5-0.9-2.12.1-1.00.40.5-0.2
Mean num. licks in bursts6.910.816.64.13.30.7-2.93.8-3.3-3.53.5
Cd content in liver1.41.55.40.30.9-2.31.50.4-1.4-0.71.0
Co content in liver0.50.51.91.0-0.2-1.40.9-0.1-0.1-0.10.6
Cu content in liver0.60.73.10.40.0-1.51.8-0.5-0.20.4-0.1
Fe content in liver1.62.03.6-0.7-1.5-0.61.9-1.71.21.7-1.4
K content in liver1.00.91.5-1.2-1.20.60.0-1.01.20.9-1.0
Mg content in liver0.70.71.3-0.6-1.10.40.2-0.91.10.9-0.9
Mn content in liver3.33.75.2-2.3-2.20.21.3-2.22.12.1-2.0
Na content in liver1.71.92.8-1.3-1.70.50.6-1.51.51.6-1.5
Rb content in liver0.50.61.6-1.3-0.50.8-0.3-0.60.80.6-0.9
Se content in liver14.216.927.8-4.9-3.7-3.25.3-4.63.14.0-3.5
Sr content in liver0.80.72.01.2-0.4-1.41.2-0.2-0.00.40.5
Zn content in liver1.82.03.6-1.5-1.4-1.31.9-1.61.01.2-1.1
Bone: minimum diameter2.24.06.31.92.02.0-2.52.2-1.7-2.11.5
Time in familiar zone, hab. session 10.10.10.4-0.60.20.5-0.40.3-0.1-0.20.1
Time in novel zone, hab. session 11.51.52.4-0.7-1.3-1.11.5-1.51.11.3-1.0
Total zone transitions, hab. session 10.30.41.0-0.7-0.51.0-0.6-0.40.60.3-0.7
Total locomotion distance, hab. session 10.40.51.0-0.3-0.80.80.2-0.80.71.0-1.0
Locomotion velocity, hab. session 10.30.51.20.1-0.71.1-0.1-0.60.60.8-0.9
Time in familiar zone, hab. session 21.01.01.80.31.3-1.10.01.0-1.4-1.01.2
Time in novel zone, hab. session 20.30.30.60.2-0.8-0.00.5-0.60.70.5-0.4
Total zone transitions, hab. session 20.10.20.8-0.9-0.1-0.00.2-0.40.10.1-0.5
Total locomotion distance, hab. session 20.40.50.8-0.8-0.6-0.40.9-0.90.40.7-0.8
Locomotion velocity, hab. session 20.60.81.1-1.1-0.8-0.10.8-1.10.71.0-1.1
Novel to familiar place preference ratio0.50.51.0-0.6-0.80.80.1-0.61.00.8-0.8
Novelty place preference0.40.40.7-0.6-0.70.80.0-0.50.90.6-0.6
Time in novel zone, NPP test0.70.81.2-0.9-1.00.70.4-0.81.10.9-0.9
Total zone transitions, NPP test0.10.10.2-0.50.2-0.10.2-0.2-0.2-0.2-0.4
Total locomotion distance, NPP test0.10.20.70.30.1-0.80.8-0.2-0.4-0.0-0.0
Locomotion velocity, NPP test0.10.10.40.20.1-0.50.6-0.2-0.30.0-0.2
Intraocular pressure1.11.52.40.91.5-1.20.41.1-1.6-1.51.3
Delta distance traveled before/after self-admin0.91.03.40.60.60.9-1.81.1-0.2-1.00.8
Delta ambulatory time before/after self-admin2.12.66.21.51.31.1-2.51.8-0.8-1.81.5
Parametrial fat weight0.61.43.6-1.9-0.50.70.4-1.30.90.8-1.9
Pavlov. Cond. lever latency0.00.00.10.2-0.0-0.2-0.20.20.0-0.20.3
Pavlov. Cond. magazine entry latency0.30.40.70.40.7-0.80.80.2-0.9-0.40.3
Pavlov. Cond. change in total contacts0.30.31.3-0.40.0-0.91.1-0.4-0.40.1-0.2
Pavlov. Cond. index score0.10.20.70.00.4-0.40.8-0.2-0.40.0-0.2
Pavlov. Cond. latency score0.10.10.4-0.00.4-0.10.6-0.2-0.40.0-0.3
Pavlov. Cond. lever contacts0.20.20.7-0.2-0.0-0.40.8-0.5-0.00.4-0.4
Pavlov. Cond. magazine entry number0.60.71.7-0.5-0.81.3-1.1-0.31.10.6-0.6
Pavlov. Cond. intertrial magazine entries0.60.82.01.20.81.1-1.40.7-0.5-0.40.2
Pavlov. Cond. lever-magazine prob. diff.0.20.21.0-0.20.2-0.51.0-0.4-0.30.2-0.3
Pavlov. Cond. response bias0.40.51.70.10.4-1.31.3-0.2-0.7-0.00.2
Pavlov. Cond. lever latency1.92.64.4-1.5-2.11.3-0.3-1.52.11.7-1.6
Pavlov. Cond. magazine entry latency0.50.62.1-0.90.4-1.51.1-0.2-0.5-0.20.0
Pavlov. Cond. change in total contacts0.30.51.40.41.2-0.4-0.10.7-1.0-0.90.5
Pavlov. Cond. index score0.60.91.90.31.4-0.90.40.7-1.3-1.10.7
Pavlov. Cond. latency score0.71.02.10.51.5-0.70.20.9-1.3-1.20.8
Pavlov. Cond. lever contacts1.82.54.21.52.0-1.20.11.5-2.0-1.81.6
Pavlov. Cond. magazine entry number0.20.30.80.6-0.40.9-0.80.10.50.30.0
Pavlov. Cond. intertrial magazine entries1.11.63.1-1.0-1.11.40.2-1.31.51.4-1.7
Pavlov. Cond. lever-magazine prob. diff.0.50.71.5-0.01.2-1.10.60.5-1.1-0.90.6
Pavlov. Cond. response bias1.11.52.70.51.6-1.50.80.9-1.6-1.21.0
Time in closed arm before self-admin1.31.72.7-0.7-1.50.61.0-1.41.61.6-1.4
Time in closed arm after self-admin1.51.63.7-1.3-0.8-1.51.9-1.40.71.2-1.1
Time in open arm before self-admin0.40.52.1-0.30.1-1.50.90.0-0.6-0.10.5
Time in open arm after self-admin0.50.61.60.40.31.3-1.20.6-0.2-0.80.4
Bone: periosteal estimation3.98.210.52.93.22.1-3.23.2-2.7-3.12.4
Bone: periosteal perimeter1.42.45.91.41.32.4-2.31.5-0.9-1.30.7
Bone: post-yield work1.01.53.40.91.91.0-1.41.2-1.3-1.40.4
Progressive ratio test 1 active lever presses3.03.78.02.31.22.1-2.82.0-1.0-1.81.5
Progressive ratio test 1 breakpoint2.63.27.12.11.12.0-2.71.8-0.9-1.61.4
Progressive ratio test 1 inactive lever presses2.73.86.92.62.00.8-2.22.1-1.7-2.11.6
Progressive ratio test 2 active lever presses2.12.58.41.80.12.9-2.60.90.2-0.50.3
Progressive ratio test 2 breakpoint2.42.78.21.90.32.9-2.81.10.0-0.70.5
Progressive ratio test 2 inactive lever presses0.91.45.21.5-0.32.3-1.90.50.4-0.10.1
Incentive Sensitization - Responses0.81.15.00.4-0.62.2-1.4-0.10.90.3-0.7
Incentive Sensitization - Breakpoint0.91.15.00.8-0.32.2-1.60.20.60.0-0.4
Sum of active levers in priming session hrs 5-61.00.93.4-1.8-0.5-0.81.1-0.80.50.5-0.6
Progressive ratio0.10.10.6-0.8-0.0-0.00.1-0.20.10.1-0.4
Food seeking constrained by brief footshock1.72.13.4-0.8-1.70.90.3-1.61.91.8-1.8
Seeking ratio, punishment vs. effort0.60.91.6-0.3-1.10.10.9-1.21.21.2-1.1
Retroperitoneal fat weight0.20.71.6-1.3-0.70.70.0-0.81.00.6-1.2
Reaction time number correct1.63.16.72.62.1-0.8-0.21.8-2.0-1.51.8
Reaction time mean minus median0.10.41.90.30.1-1.40.60.1-0.3-0.30.6
Reaction time mean minus median AUC0.41.03.11.30.5-1.80.60.4-0.8-0.71.0
Reaction time num false alarms1.31.83.3-1.8-1.20.80.3-1.41.41.5-1.7
Reaction time num false alarms AUC1.42.14.8-2.2-1.20.50.8-1.61.31.6-1.8
Reaction time trials correct on left1.63.16.72.62.1-0.8-0.21.8-2.0-1.51.8
Reaction time trials on left1.63.06.72.62.1-0.8-0.21.8-2.0-1.41.8
Reaction time mean0.60.91.7-1.3-1.1-1.01.0-1.00.80.7-0.5
Reaction time mean AUC0.60.91.6-1.1-1.0-1.31.1-0.90.70.7-0.3
Median of all reaction times0.91.32.8-1.7-1.3-0.91.0-1.21.00.9-0.7
Reaction time omissions0.50.83.20.2-0.4-1.81.5-0.60.10.60.0
Reaction time false alarm rate3.64.99.8-3.1-2.21.00.6-2.42.42.2-2.6
Reaction time premature initiation rate0.71.04.40.8-0.32.1-1.4-0.10.60.3-0.8
Reaction time premature initiations1.01.85.72.41.21.5-1.51.1-0.8-0.80.4
Std. dev. reaction times0.30.63.0-0.5-0.3-1.71.2-0.50.10.20.1
Reaction time trials completed1.63.06.72.62.1-0.8-0.21.8-2.0-1.41.8
Reaction time trials AUC1.52.95.82.42.1-1.0-0.01.7-1.9-1.41.8
Run reversals in cocaine runway, females0.40.40.60.80.5-0.8-0.10.6-0.6-0.30.8
Run reversals in cocaine runway, males1.91.93.0-1.3-1.30.81.0-1.61.41.7-1.7
Latency to leave start box in cocaine runway0.60.71.6-0.9-1.20.90.1-0.71.20.7-0.5
Latency to leave start box in cocaine runway, F2.12.44.1-1.7-2.00.60.9-1.71.91.6-1.4
Latency to leave start box in cocaine runway, M0.20.10.50.10.10.7-0.50.3-0.1-0.40.2
Std. dev. time between licks in bursts1.92.58.6-1.2-0.7-2.92.8-1.20.30.6-0.2
Total sessions with >9 infusions0.40.51.60.10.61.3-1.20.6-0.2-0.70.1
Short access day 1 total inactive lever presses1.11.43.91.70.31.8-2.01.0-0.2-0.50.6
Short access day 10 total inactive lever presses0.30.71.80.70.91.3-1.20.6-0.5-0.6-0.1
Short access day 1 total infusions0.50.73.30.10.01.8-1.30.40.3-0.3-0.1
Short access day 10 total infusions0.50.61.91.40.50.7-0.80.8-0.5-0.50.6
Short access total infusions0.91.12.71.10.71.6-1.61.0-0.4-0.80.6
Short access day 1 locomotion0.30.41.5-0.1-0.51.2-0.7-0.10.60.4-0.3
Short access day 10 total locomotion0.71.32.3-0.6-1.51.4-0.5-0.91.41.4-0.9
Short access total locomotion0.50.61.5-0.3-1.01.2-0.5-0.51.00.7-0.5
One hour access (0.3 mA shock)2.83.25.42.31.51.6-2.21.9-1.3-1.61.5
Compulsive drug intake0.40.51.00.01.00.3-0.70.8-0.7-0.90.6
One hour access (shock baseline)0.30.41.21.0-0.61.1-0.3-0.30.60.6-0.4
Social response proportion0.20.20.70.3-0.80.4-0.30.00.60.20.2
Social responses0.00.10.20.5-0.10.10.10.20.1-0.10.3
Social time0.10.10.50.20.4-0.40.7-0.1-0.20.1-0.1
Soleus weight0.20.51.00.10.60.1-0.71.0-0.5-1.01.0
Bone: stiffness0.91.53.20.21.51.8-1.71.2-1.0-1.10.3
Tibialis anterior weight0.62.09.9-0.4-0.53.1-2.10.21.00.1-0.6
Time to tail flick, vehicle, before self-admin0.10.10.30.6-0.1-0.50.40.2-0.2-0.00.6
Time to tail flick, vehicle, after self-admin0.20.30.8-0.80.30.8-0.4-0.30.00.0-0.9
Time to tail flick, test, before self-admin0.50.52.61.60.4-0.2-0.20.6-0.5-0.30.8
Time to tail flick, test, after self-admin1.31.44.72.21.2-0.8-0.11.0-1.3-0.71.1
Delta time to tail flick, vehicle, before/after SA1.31.24.8-0.70.12.2-1.5-0.30.50.2-1.3
Delta time to tail flick, test, before/after SA0.00.00.10.3-0.00.3-0.0-0.1-0.00.2-0.2
Tibia length0.71.83.30.91.81.5-1.71.5-1.4-1.10.6
Ambulatory time before self-admin0.81.21.9-0.6-1.3-1.11.3-1.20.91.4-0.7
Ambulatory time after self-admin0.40.51.30.8-0.70.7-1.10.10.80.20.2
Bone: tissue strength0.20.20.40.40.3-0.60.40.2-0.5-0.40.4
Total heroin consumption1.11.33.8-1.1-0.71.9-1.0-0.71.10.5-1.4
Bone: trabecular number2.84.66.32.42.50.4-1.92.4-2.3-2.42.1
Bone: trabecular spacing1.11.52.6-1.6-1.10.01.0-1.41.21.1-1.5
Bone: trabecular thickness3.54.48.62.92.40.3-1.62.3-2.2-2.11.9
Bone: trabecular tissue density0.60.92.90.90.41.4-1.70.9-0.0-0.60.5
Water consumed over 24 hours0.70.92.6-1.6-0.60.80.2-0.90.90.7-1.3
Number of responses in last shaping day1.21.32.01.41.00.6-1.21.4-0.9-1.21.2