Hub : Genes

LOC102548791

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL gene expression LOC102548791 0.09 0.05 4.6e-11 0.07 0.09 0.08 0.07 6.2e-08 6.6e-10 8.7e-09 4.5e-08
2 IC gene expression LOC102548791 0.14 0.09 2.9e-04 0.03 0.05 0.03 0.03 1.7e-02 3.0e-03 2.6e-02 1.6e-02
3 Adipose gene expression LOC102548791 0.11 0.06 7.2e-15 0.12 0.11 0.11 0.12 7.2e-13 2.5e-12 3.6e-12 7.9e-13
4 RMTg gene expression LOC102548791 0.3 0.16 5.1e-04 0.11 0.13 0.11 0.14 8.6e-04 2.4e-04 9.5e-04 1.9e-04
5 Brain gene expression LOC102548791 0.11 0.06 1.4e-11 0.11 0.13 0.13 0.13 2.9e-10 3.3e-12 3.6e-12 3.0e-12
6 pVTA gene expression LOC102548791 0.11 0.06 6.8e-09 0.09 0.09 0.09 0.08 6.9e-08 1.0e-07 1.8e-07 4.5e-07
7 Liver gene expression LOC102548791 0.31 0.14 0.0e+00 0.26 0.25 0.26 0.26 3.8e-29 4.6e-28 7.7e-29 6.0e-29
8 NAcc gene expression LOC102548791 0.08 0.04 6.0e-15 0.1 0.1 0.1 0.1 3.1e-15 5.5e-15 1.9e-14 1.3e-14

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.71.31.8-1.0-1.0-1.3-0.7-0.9-1.2-1.3-1.3
Area under the delay curve2.22.53.71.71.71.31.91.91.41.41.4
BMI with tail0.31.02.4-1.0-1.1-0.2-1.4-1.6-0.8-0.7-0.7
BMI without tail0.41.22.1-1.3-1.4-0.2-0.7-1.4-1.1-1.0-1.0
Body weight0.21.03.00.80.71.71.10.30.90.91.0
Weight adjusted by age0.10.20.90.50.40.50.90.40.1-0.2-0.1
Bone surface0.91.62.91.71.70.81.61.70.60.60.7
Bone volume0.10.20.50.60.6-0.10.50.7-0.2-0.3-0.2
Breakpoint value in progressive ratio session0.20.30.70.30.2-0.2-0.2-0.1-0.8-0.8-0.8
Number of licking bursts0.00.10.20.20.20.40.30.10.20.20.2
Context. condit. distance diff. score0.10.20.40.60.60.10.20.30.50.30.3
Locomotion velocity, session 11.41.62.30.90.91.51.21.31.51.31.3
Locomotion distance, session 12.12.73.8-1.9-2.0-1.4-1.5-1.5-1.5-1.6-1.6
Locomotion velocity, session 20.60.61.0-1.0-1.0-0.8-0.9-0.6-0.6-0.8-0.8
Locomotion distance, session 25.07.09.6-3.1-3.1-2.3-2.4-2.4-2.4-2.6-2.6
Locomotion velocity, session 30.50.50.90.50.60.70.70.90.80.80.8
Locomotion distance, session 30.50.50.8-0.9-0.9-0.5-0.9-0.9-0.5-0.4-0.4
Stereotopy head waving bouts, day 31.01.21.91.41.40.90.81.11.11.01.0
Stereotopy head waving duration, day 31.21.52.31.51.50.91.01.31.21.11.1
Locomotion velocity, session 70.10.10.40.40.30.40.60.50.10.10.1
Locomotion distance, session 72.32.94.1-1.6-1.7-1.5-1.3-1.5-2.0-2.0-2.0
Stereotopy head waving bouts, day 73.33.75.12.22.31.41.51.82.02.02.0
Stereotopy head waving duration, day 75.16.17.92.72.81.82.12.52.52.62.6
Locomotion velocity, session 81.31.51.91.31.31.11.41.41.21.11.1
Locomotion distance, session 82.43.44.0-1.9-1.9-1.9-1.7-1.7-1.7-2.0-2.0
Degree of sensitization distance1.51.52.9-0.9-1.0-1.1-0.5-0.6-1.6-1.7-1.7
Degree of sensitization stereotypy1.21.31.81.31.40.70.91.01.21.31.3
Conditioned locomotion0.30.30.6-0.4-0.4-0.4-0.5-0.2-0.7-0.8-0.7
Cocaine response after cond. corrected0.00.10.20.20.20.40.10.10.20.20.1
Cocaine response after cond. not corrected0.20.20.50.40.40.70.60.50.40.30.3
Cocaine response before conditioning0.40.41.30.50.50.51.10.80.40.50.5
Saline control response0.81.11.90.60.61.01.41.21.21.21.2
Bone: connectivity density0.40.61.0-0.7-0.7-0.9-0.1-0.4-0.9-1.0-1.0
Bone: cortical apparent density2.63.64.9-2.2-2.2-1.7-2.0-2.2-1.5-1.6-1.7
Bone: cortical area1.01.63.01.11.11.70.70.81.41.41.4
Bone: cortical porosity1.61.82.41.51.51.11.31.51.11.21.2
Bone: cortical porosity2.83.03.92.02.01.51.72.01.51.61.6
Bone: cortical thickness0.50.92.1-1.3-1.30.7-1.1-1.40.30.30.2
Bone: cortical thickness0.40.40.9-0.9-0.90.1-0.9-1.0-0.1-0.2-0.1
Bone: cortical tissue density2.73.74.9-2.2-2.2-1.8-2.0-2.2-1.5-1.7-1.7
Condit. Reinf. active minus inactive responses0.10.10.3-0.2-0.1-0.6-0.30.1-0.2-0.3-0.3
Condit. Reinf. active-inactive response ratio0.10.10.5-0.1-0.1-0.7-0.20.2-0.3-0.5-0.5
Condit. Reinf. active responses0.20.30.5-0.6-0.5-0.7-0.6-0.1-0.5-0.5-0.5
Condit. Reinf. inactive responses0.30.40.6-0.8-0.7-0.5-0.6-0.5-0.6-0.5-0.5
Incentive salience index mean0.00.00.20.00.1-0.5-0.20.30.1-0.0-0.0
Condit. Reinf. lever presses0.10.20.4-0.4-0.3-0.7-0.5-0.1-0.3-0.3-0.3
Condit. Reinf. active minus inactive responses0.81.01.61.01.01.01.30.90.90.90.9
Condit. Reinf. active-inactive response ratio0.60.71.00.80.80.91.00.80.70.70.7
Condit. Reinf. active responses0.00.00.10.00.0-0.10.3-0.0-0.2-0.2-0.2
Condit. Reinf. inactive responses0.50.71.1-0.8-0.8-1.1-0.7-0.8-0.8-0.8-0.9
Condit. Reinf. lever presses0.60.81.4-0.8-0.8-1.2-0.7-0.7-1.0-1.0-1.0
Condit. Reinf. lever reinforcers received0.20.30.4-0.4-0.4-0.6-0.3-0.5-0.6-0.6-0.6
Conditioned reinforcement - actives1.01.82.6-1.3-1.4-0.8-1.3-1.6-1.5-1.3-1.3
Conditioned reinforcement - inactives0.00.00.1-0.2-0.10.20.0-0.40.10.10.1
Conditioned locomotion1.82.43.4-1.5-1.5-0.5-1.2-1.8-1.8-1.8-1.8
Patch foraging indifference point 0 sec1.22.24.4-1.4-1.3-2.1-1.5-1.3-1.5-1.4-1.3
Patch foraging indifference point AUC0.10.20.4-0.3-0.3-0.30.2-0.1-0.6-0.5-0.5
Delay disc. indifference point, 0s delay2.02.22.81.31.41.51.61.71.51.51.5
Delay disc. indifference point, 16s delay0.10.10.2-0.1-0.1-0.4-0.1-0.0-0.4-0.4-0.4
Delay disc. indifference point, 2s delay1.11.23.01.11.10.71.71.30.70.70.7
Delay disc. indifference point, 24s delay0.00.00.20.10.10.30.40.30.10.10.1
Delay disc. indifference point, 4s delay2.72.83.71.71.71.41.91.91.51.51.5
Delay disc. indifference point, 8s delay6.17.18.42.72.72.42.92.82.62.62.6
Indifference point function ln k0.81.53.7-1.2-1.2-1.1-1.9-1.5-0.7-0.8-0.8
Indifference point function log k0.81.53.7-1.2-1.2-1.1-1.9-1.5-0.7-0.8-0.8
Patch foraging total patch changes 0 sec1.63.15.5-1.7-1.6-2.3-1.8-1.6-1.7-1.6-1.6
Patch foraging total patch changes 12 sec2.12.73.7-1.7-1.7-1.9-1.2-1.5-1.8-1.7-1.6
Patch foraging total patch changes 18 sec1.21.93.9-1.0-1.0-2.0-1.0-0.9-1.6-1.5-1.5
Patch foraging total patch changes 24 sec0.30.51.00.90.9-0.10.71.00.50.60.6
Patch foraging total patch changes 6 sec1.62.43.8-1.6-1.6-1.9-1.4-1.5-1.5-1.4-1.4
Patch foraging time to switch 0 sec0.30.50.60.80.80.80.60.70.80.70.7
Patch foraging water rate 0 sec0.30.71.0-0.9-0.9-0.9-0.5-0.7-1.0-0.9-0.9
Patch foraging water rate 12 sec1.43.05.9-1.8-1.8-1.3-2.4-2.0-1.5-1.4-1.3
Patch foraging water rate 18 sec0.71.11.5-0.9-0.9-1.1-1.2-1.0-1.1-1.0-1.0
Patch foraging water rate 24 sec1.92.73.1-1.4-1.4-1.7-1.7-1.5-1.8-1.8-1.7
Patch foraging water rate 6 sec0.60.91.4-1.1-1.2-0.7-1.2-1.1-0.7-0.6-0.7
Seeking ratio, delayed vs. immediate footshock0.10.10.70.10.10.20.90.40.30.10.1
Distance traveled before self-admin0.60.81.00.80.90.70.90.70.91.01.0
Distance traveled after self-admin1.41.73.2-1.0-1.0-1.8-1.2-1.1-1.4-1.3-1.3
Extensor digitorum longus weight1.66.27.0-2.6-2.7-2.3-2.5-2.5-2.4-2.5-2.4
Bone: elastic displacement2.12.43.8-1.9-1.9-1.2-1.6-1.8-1.3-1.2-1.3
Bone: elastic work0.10.20.4-0.5-0.50.1-0.5-0.70.20.20.1
Bone: endosteal estimation0.91.94.72.22.10.31.32.00.40.40.5
Bone: endosteal perimeter4.49.415.63.93.92.13.13.82.22.32.4
Epididymis fat weight0.10.30.6-0.3-0.40.6-0.2-0.8-0.8-0.6-0.6
Delta time in closed arm before/after self-admin0.20.20.50.50.50.30.50.7-0.2-0.00.0
Delta time in open arm before/after self-admin0.70.71.5-1.0-0.9-1.2-0.6-0.6-0.6-0.6-0.6
Diff in mean of infusions in LGA sessions0.50.61.51.21.20.10.91.00.10.10.2
Delay discount exponential model param2.62.94.1-1.8-1.8-1.4-2.0-2.0-1.5-1.5-1.5
Extinction: sum of active levers before priming0.40.51.1-0.7-0.7-0.6-1.0-0.8-0.6-0.5-0.5
Active lever presses in extinction session 60.30.30.5-0.2-0.3-0.40.1-0.7-0.6-0.7-0.6
Bone: final force0.81.21.90.90.81.31.00.61.41.31.3
Bone: final moment0.81.21.90.90.91.30.90.61.41.31.3
Food consumed during 24 hour testing period0.40.61.40.80.80.30.81.20.60.70.7
Glucose0.10.10.20.20.20.3-0.1-0.20.40.40.5
Heart weight0.20.20.7-0.3-0.30.8-0.5-0.70.30.40.4
Delay discount hyperbolic model param2.62.94.3-1.8-1.8-1.4-2.1-2.0-1.5-1.5-1.5
Intermittent access intake day 1-15 change0.40.81.30.70.70.90.60.91.11.11.1
Intermittent access intake escalation0.20.50.90.40.40.80.30.60.90.90.9
Intermittent access intake escalation 20.60.71.50.60.61.20.90.70.80.70.7
Intermitt. access day 1 inactive lever presses0.10.30.50.50.6-0.6-0.10.30.60.70.7
Intermitt. access day 15 inactive lever presses0.10.20.3-0.3-0.3-0.5-0.5-0.4-0.5-0.4-0.4
Intermitt. access escalation Index0.40.61.20.70.8-0.30.11.10.80.80.8
Intermittent access day 1 total infusions1.01.62.5-0.9-1.0-1.4-1.5-1.6-1.4-1.1-1.1
Intermittent access day 15 total infusions0.20.30.7-0.6-0.5-0.5-0.8-0.6-0.6-0.3-0.3
Intermittent access terminal intake (last 3 days)0.00.00.10.10.1-0.1-0.3-0.2-0.30.10.1
Intermittent access total infusions0.40.40.8-0.4-0.4-0.8-0.9-0.9-0.8-0.4-0.4
Intermittent access day 1 locomotion1.41.82.7-1.2-1.2-0.9-0.8-1.5-1.6-1.5-1.5
Intermittent access day 15 total locomotion0.10.20.7-0.5-0.50.0-0.2-0.9-0.5-0.4-0.4
Intermittent access total locomotion0.70.81.5-0.8-0.9-0.5-0.6-1.2-1.1-1.0-1.0
Intermittent access standard deviation1.93.95.22.22.21.81.31.52.12.32.3
Left kidney weight0.83.85.81.91.82.42.01.42.01.92.0
Right kidney weight0.10.62.60.50.41.60.90.20.60.60.7
Cocaine induced anxiety0.91.32.50.70.71.41.20.91.61.11.1
Post-drug Anxiety0.20.20.7-0.1-0.10.70.0-0.20.80.30.3
Baseline Anxiety0.81.01.5-0.7-0.7-1.0-1.2-0.9-1.2-1.0-1.0
Tail length0.62.26.41.11.12.02.51.31.00.90.9
Length with tail1.87.713.42.72.53.43.72.52.52.42.3
Length without tail1.44.45.92.22.12.42.11.72.12.12.0
Times rat made contact with spout0.10.10.2-0.2-0.2-0.4-0.2-0.1-0.3-0.3-0.3
Lifetime Intake0.30.40.8-0.4-0.4-0.6-0.8-0.9-0.8-0.4-0.4
Liver weight, left0.61.01.41.21.21.00.70.90.90.91.0
Liver weight, right1.12.02.61.61.61.31.51.41.21.21.2
Locomotor activity0.00.10.2-0.2-0.20.1-0.2-0.1-0.4-0.4-0.4
Locomotor testing distance0.10.20.5-0.1-0.1-0.1-0.0-0.1-0.6-0.6-0.7
Locomotor testing rearing0.30.60.9-0.7-0.7-0.7-0.5-0.3-0.9-0.9-1.0
Locomotion in novel chamber0.10.10.40.30.3-0.30.30.6-0.3-0.4-0.4
Locomotion in novel chamber post-restriction0.30.51.01.01.0-0.30.41.00.60.60.6
Fecal boli incidents, locomotor time 10.71.01.3-0.7-0.8-1.0-1.0-1.0-1.1-1.1-1.1
Change in fecal boli incidents, locomotor task0.20.20.5-0.4-0.3-0.6-0.7-0.5-0.1-0.1-0.1
Time >=10cm from walls, locomotor time 10.40.41.00.70.70.10.61.00.50.60.5
Bouts of movement, locomotor time 10.40.51.1-0.7-0.7-0.5-1.0-0.6-0.6-0.7-0.6
Total resting periods, locomotor time 10.60.71.5-0.9-0.8-0.8-1.2-0.8-0.7-0.8-0.7
Rest time, locomotor task time 10.10.10.5-0.2-0.3-0.0-0.7-0.7-0.0-0.1-0.1
Distance moved, locomotor task time 10.10.20.50.30.30.00.70.60.20.30.3
Vertical activity count, locomotor time 10.10.20.4-0.4-0.4-0.00.1-0.1-0.6-0.5-0.6
Time >=10cm from walls, locomotor time 20.10.10.2-0.5-0.5-0.1-0.1-0.3-0.2-0.2-0.3
Bouts of movement, locomotor time 20.00.00.10.20.20.20.10.00.10.10.1
Total resting periods, locomotor time 20.00.00.10.30.30.30.00.10.10.10.0
Rest time, locomotor task time 20.20.20.60.70.60.80.00.30.30.20.2
Distance moved, locomotor task time 20.10.10.2-0.5-0.50.10.2-0.3-0.1-0.0-0.0
Vertical activity count, locomotor time 20.10.20.4-0.6-0.60.0-0.2-0.5-0.4-0.4-0.4
Light reinforcement 11.33.13.7-1.9-1.9-1.5-1.6-1.8-1.8-1.7-1.7
Light reinforcement 20.00.00.2-0.2-0.20.50.1-0.10.10.10.1
Bone: marrow area0.91.94.72.22.10.31.32.00.40.40.5
Bone: maximum diameter5.410.113.93.73.73.02.83.42.92.92.9
Bone: maximum force0.50.81.30.90.81.00.80.41.11.11.1
Bone: maximum moment0.50.81.20.90.80.90.70.51.11.11.1
Mean time between licks in bursts0.00.00.10.00.00.1-0.10.10.20.20.2
Mean num. licks in bursts0.50.71.4-0.8-0.8-1.2-0.9-0.6-0.8-0.8-0.8
Cd content in liver3.13.44.4-1.8-1.7-2.0-2.1-1.8-1.9-1.8-1.7
Co content in liver0.20.30.6-0.4-0.3-0.8-0.7-0.3-0.6-0.4-0.4
Cu content in liver0.10.10.30.30.30.40.40.50.20.30.4
Fe content in liver0.20.30.90.70.7-0.00.51.00.10.10.1
K content in liver0.00.00.2-0.2-0.1-0.5-0.10.0-0.2-0.10.0
Mg content in liver1.51.52.0-1.3-1.2-1.4-1.0-1.1-1.4-1.3-1.2
Mn content in liver0.40.40.70.50.50.80.70.70.60.60.7
Na content in liver0.10.10.40.30.40.10.50.60.30.30.3
Rb content in liver0.80.91.4-1.2-1.2-0.8-0.7-1.1-0.9-1.0-1.0
Se content in liver0.20.20.4-0.3-0.3-0.30.10.1-0.6-0.7-0.6
Sr content in liver0.30.30.5-0.6-0.6-0.4-0.7-0.6-0.4-0.4-0.3
Zn content in liver0.00.00.00.00.0-0.0-0.2-0.00.10.10.1
Bone: minimum diameter2.13.85.82.42.41.41.82.41.61.61.6
Time in familiar zone, hab. session 10.30.30.8-0.5-0.4-0.9-0.9-0.6-0.3-0.3-0.3
Time in novel zone, hab. session 11.11.11.80.90.91.31.31.00.90.90.9
Total zone transitions, hab. session 11.31.82.5-1.6-1.6-1.2-1.2-1.1-1.3-1.4-1.4
Total locomotion distance, hab. session 11.31.92.5-1.6-1.6-1.1-1.2-1.2-1.4-1.5-1.5
Locomotion velocity, hab. session 12.02.83.6-1.9-1.9-1.4-1.5-1.5-1.7-1.8-1.8
Time in familiar zone, hab. session 20.20.20.6-0.4-0.4-0.5-0.6-0.7-0.4-0.4-0.4
Time in novel zone, hab. session 20.40.40.70.70.70.40.60.80.60.60.6
Total zone transitions, hab. session 25.46.97.8-2.8-2.8-2.5-2.3-2.4-2.7-2.8-2.8
Total locomotion distance, hab. session 26.17.99.2-3.0-3.0-2.5-2.6-2.7-2.8-2.9-2.9
Locomotion velocity, hab. session 25.67.59.0-3.0-3.0-2.4-2.5-2.6-2.7-2.8-2.8
Novel to familiar place preference ratio2.62.93.7-1.6-1.6-1.9-1.5-1.5-1.8-1.8-1.8
Novelty place preference2.02.12.8-1.4-1.4-1.7-1.3-1.3-1.5-1.5-1.5
Time in novel zone, NPP test2.52.63.5-1.5-1.5-1.9-1.5-1.5-1.6-1.7-1.7
Total zone transitions, NPP test3.04.35.4-2.3-2.3-1.9-1.8-1.9-2.0-2.1-2.1
Total locomotion distance, NPP test7.710.512.7-3.6-3.6-3.1-3.1-3.1-3.0-3.2-3.2
Locomotion velocity, NPP test6.38.910.8-3.3-3.3-2.8-2.8-2.9-2.8-3.0-3.0
Intraocular pressure0.71.01.8-0.6-0.6-1.3-1.0-0.9-1.2-1.2-1.1
Delta distance traveled before/after self-admin2.93.03.8-1.6-1.6-1.9-1.7-1.5-1.8-1.8-1.8
Delta ambulatory time before/after self-admin2.83.44.4-1.7-1.7-2.1-1.7-1.5-2.1-2.0-2.0
Parametrial fat weight0.10.20.4-0.1-0.1-0.4-0.5-0.4-0.6-0.5-0.4
Pavlov. Cond. lever latency0.20.30.5-0.1-0.1-0.7-0.2-0.3-0.7-0.6-0.7
Pavlov. Cond. magazine entry latency3.03.94.12.02.02.02.02.01.91.91.9
Pavlov. Cond. change in total contacts0.90.91.4-1.1-1.1-0.8-1.2-1.0-0.8-0.7-0.8
Pavlov. Cond. index score1.21.51.81.11.11.41.11.21.31.31.3
Pavlov. Cond. latency score1.62.02.51.31.31.61.31.41.61.51.5
Pavlov. Cond. lever contacts0.10.10.2-0.3-0.3-0.0-0.4-0.10.20.20.2
Pavlov. Cond. magazine entry number2.53.23.4-1.8-1.8-1.8-1.7-1.7-1.8-1.8-1.8
Pavlov. Cond. intertrial magazine entries1.92.23.3-1.4-1.4-1.8-1.4-1.3-1.6-1.5-1.5
Pavlov. Cond. lever-magazine prob. diff.0.80.91.10.80.91.10.81.01.01.01.0
Pavlov. Cond. response bias1.11.31.51.11.11.21.01.11.21.21.2
Pavlov. Cond. lever latency0.40.61.30.40.41.10.50.30.90.90.9
Pavlov. Cond. magazine entry latency1.41.73.1-0.9-0.9-1.7-1.8-1.3-1.2-1.1-1.2
Pavlov. Cond. change in total contacts1.42.23.7-1.2-1.1-1.9-1.7-1.3-1.5-1.5-1.5
Pavlov. Cond. index score1.11.52.7-0.8-0.8-1.7-1.4-0.9-1.3-1.2-1.3
Pavlov. Cond. latency score0.71.02.1-0.5-0.5-1.5-1.2-0.6-1.0-1.0-1.0
Pavlov. Cond. lever contacts0.81.12.1-0.7-0.7-1.4-0.9-0.5-1.2-1.2-1.2
Pavlov. Cond. magazine entry number1.41.73.40.90.91.81.71.21.21.21.2
Pavlov. Cond. intertrial magazine entries0.71.13.21.00.91.11.81.50.40.40.4
Pavlov. Cond. lever-magazine prob. diff.1.01.42.7-0.7-0.7-1.7-1.4-0.9-1.2-1.2-1.2
Pavlov. Cond. response bias1.52.13.5-1.2-1.2-1.9-1.5-1.2-1.5-1.5-1.5
Time in closed arm before self-admin0.10.20.5-0.4-0.40.4-0.4-0.70.40.30.3
Time in closed arm after self-admin0.20.20.70.40.40.8-0.30.00.50.50.5
Time in open arm before self-admin0.20.20.60.40.40.40.80.4-0.00.00.0
Time in open arm after self-admin0.50.62.1-0.6-0.6-1.4-0.1-0.4-0.8-0.8-0.8
Bone: periosteal estimation1.42.95.22.32.21.41.42.01.31.31.3
Bone: periosteal perimeter4.98.410.53.23.22.82.72.92.72.72.8
Bone: post-yield work0.71.01.8-0.8-0.8-1.4-0.9-0.9-1.1-1.1-1.0
Progressive ratio test 1 active lever presses0.70.81.4-0.7-0.7-0.9-0.9-0.9-1.2-0.9-0.9
Progressive ratio test 1 breakpoint0.70.81.4-0.7-0.7-0.9-0.9-0.9-1.2-0.9-0.9
Progressive ratio test 1 inactive lever presses0.00.10.50.10.2-0.7-0.1-0.1-0.10.10.1
Progressive ratio test 2 active lever presses1.21.42.2-1.1-1.1-0.8-1.1-1.4-1.5-1.2-1.2
Progressive ratio test 2 breakpoint1.11.21.9-1.1-1.1-0.7-1.1-1.4-1.4-1.0-1.0
Progressive ratio test 2 inactive lever presses0.10.10.3-0.3-0.30.0-0.3-0.6-0.5-0.2-0.2
Incentive Sensitization - Responses0.00.00.2-0.00.00.3-0.2-0.40.00.20.2
Incentive Sensitization - Breakpoint0.00.10.10.10.10.3-0.2-0.30.10.30.3
Sum of active levers in priming session hrs 5-60.50.41.3-0.3-0.3-1.1-0.8-0.6-0.7-0.5-0.5
Progressive ratio0.81.21.6-0.7-0.8-1.2-1.3-1.2-1.2-1.2-1.2
Food seeking constrained by brief footshock0.20.20.30.50.50.20.10.20.50.60.6
Seeking ratio, punishment vs. effort0.71.01.30.90.90.90.91.01.11.11.1
Retroperitoneal fat weight0.10.41.00.60.61.01.00.3-0.2-0.1-0.1
Reaction time number correct1.32.53.3-1.4-1.4-1.8-1.4-1.2-1.8-1.7-1.8
Reaction time mean minus median0.10.30.90.30.41.00.30.20.70.70.7
Reaction time mean minus median AUC0.51.42.21.01.01.51.01.01.21.31.3
Reaction time num false alarms0.00.10.1-0.1-0.1-0.2-0.2-0.2-0.3-0.4-0.3
Reaction time num false alarms AUC0.10.20.4-0.2-0.3-0.3-0.2-0.4-0.6-0.6-0.6
Reaction time trials correct on left1.32.53.3-1.4-1.4-1.8-1.4-1.2-1.8-1.7-1.8
Reaction time trials on left1.32.43.2-1.3-1.3-1.8-1.3-1.2-1.8-1.7-1.8
Reaction time mean0.00.00.1-0.1-0.10.3-0.1-0.1-0.0-0.0-0.1
Reaction time mean AUC0.10.10.2-0.4-0.40.0-0.4-0.4-0.3-0.3-0.3
Median of all reaction times0.00.00.0-0.1-0.10.1-0.2-0.1-0.1-0.1-0.2
Reaction time omissions1.01.52.11.21.21.51.21.21.11.11.1
Reaction time false alarm rate0.20.20.50.50.40.70.50.30.40.30.4
Reaction time premature initiation rate3.95.47.0-2.6-2.6-1.8-2.2-2.4-2.3-2.3-2.3
Reaction time premature initiations5.08.99.7-3.1-3.1-2.7-2.8-2.8-3.1-3.0-3.1
Std. dev. reaction times0.00.00.1-0.2-0.20.2-0.2-0.30.10.10.1
Reaction time trials completed1.32.43.2-1.3-1.3-1.8-1.3-1.2-1.8-1.7-1.8
Reaction time trials AUC1.63.14.0-1.6-1.6-2.0-1.5-1.4-2.0-1.9-2.0
Run reversals in cocaine runway, females0.10.10.40.30.3-0.7-0.30.00.50.30.3
Run reversals in cocaine runway, males0.20.20.6-0.4-0.5-0.2-0.4-0.8-0.2-0.2-0.4
Latency to leave start box in cocaine runway0.60.61.1-0.9-0.9-0.9-1.0-1.0-0.5-0.4-0.5
Latency to leave start box in cocaine runway, F0.60.71.0-0.9-0.9-0.8-1.0-1.0-0.7-0.6-0.5
Latency to leave start box in cocaine runway, M0.40.40.6-0.7-0.7-0.7-0.7-0.8-0.4-0.4-0.6
Std. dev. time between licks in bursts0.60.91.4-0.8-0.9-1.0-0.4-0.5-1.2-1.2-1.2
Total sessions with >9 infusions0.10.10.50.10.1-0.2-0.5-0.7-0.5-0.2-0.2
Short access day 1 total inactive lever presses0.91.21.51.21.21.11.20.80.91.01.0
Short access day 10 total inactive lever presses0.81.92.71.51.50.71.21.61.41.51.5
Short access day 1 total infusions0.00.10.20.20.2-0.2-0.3-0.4-0.30.00.0
Short access day 10 total infusions0.10.10.40.60.6-0.5-0.2-0.0-0.20.10.1
Short access total infusions0.20.30.6-0.2-0.1-0.5-0.8-0.8-0.7-0.4-0.4
Short access day 1 locomotion0.00.00.10.00.00.20.1-0.3-0.1-0.1-0.1
Short access day 10 total locomotion0.10.10.30.50.50.20.50.10.20.20.2
Short access total locomotion0.10.10.40.50.40.60.2-0.20.30.30.3
One hour access (0.3 mA shock)1.41.63.2-1.2-1.2-0.7-1.8-1.5-1.3-1.1-1.1
Compulsive drug intake0.20.20.4-0.5-0.5-0.2-0.1-0.6-0.3-0.6-0.6
One hour access (shock baseline)0.10.10.4-0.3-0.3-0.2-0.7-0.4-0.5-0.2-0.2
Social response proportion0.40.50.7-0.7-0.7-0.1-0.7-0.8-0.7-0.7-0.7
Social responses0.00.10.2-0.4-0.4-0.1-0.3-0.3-0.1-0.1-0.1
Social time0.60.81.1-1.0-1.0-0.7-1.1-1.1-0.7-0.7-0.7
Soleus weight0.61.82.7-1.6-1.6-0.9-1.4-1.5-1.2-1.2-1.1
Bone: stiffness0.71.21.91.00.91.30.90.71.41.31.3
Tibialis anterior weight0.41.42.0-1.3-1.3-1.1-1.4-1.1-1.0-1.0-0.9
Time to tail flick, vehicle, before self-admin0.10.10.3-0.5-0.5-0.4-0.2-0.3-0.1-0.2-0.2
Time to tail flick, vehicle, after self-admin0.30.40.80.50.60.30.40.10.70.80.9
Time to tail flick, test, before self-admin0.10.10.2-0.2-0.3-0.40.50.1-0.2-0.4-0.4
Time to tail flick, test, after self-admin2.12.22.91.61.51.31.71.21.61.51.4
Delta time to tail flick, vehicle, before/after SA0.20.20.50.70.70.20.50.40.20.30.4
Delta time to tail flick, test, before/after SA1.81.92.51.31.41.50.91.01.51.61.6
Tibia length14.038.644.26.16.16.76.05.66.46.46.4
Ambulatory time before self-admin1.01.52.21.11.21.01.11.01.41.51.5
Ambulatory time after self-admin0.80.91.7-0.7-0.8-1.3-0.9-0.9-1.1-1.0-0.9
Bone: tissue strength1.11.11.8-1.0-1.0-1.3-1.0-1.2-0.9-0.8-0.9
Total heroin consumption1.41.62.51.61.61.11.21.51.01.01.0
Bone: trabecular number0.00.00.1-0.1-0.1-0.40.20.2-0.2-0.2-0.2
Bone: trabecular spacing0.00.00.10.30.30.1-0.20.20.10.20.2
Bone: trabecular thickness0.20.30.5-0.5-0.5-0.6-0.3-0.3-0.7-0.7-0.7
Bone: trabecular tissue density0.20.30.80.40.40.90.70.40.60.60.5
Water consumed over 24 hours0.00.00.1-0.2-0.2-0.2-0.1-0.0-0.00.00.0
Number of responses in last shaping day0.30.30.50.70.70.70.30.30.40.60.6