LOC102548791

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL gene expression LOC102548791 0.52 0.16 1.3e-12 0.27 0.34 0.32 0.31 3.1e-07 6.3e-09 1.8e-08 3.2e-08
2 Brain gene expression LOC102548791 0.18 0.08 0.0e+00 0.16 0.2 0.2 0.21 1.1e-14 1.0e-18 1.4e-18 6.0e-19
3 PL gene expression LOC102548791 0.16 0.08 0.0e+00 0.17 0.19 0.17 0.18 7.9e-19 3.3e-20 7.2e-19 1.1e-19
4 Liver gene expression LOC102548791 0.2 0.09 0.0e+00 0.23 0.23 0.22 0.23 2.6e-25 1.2e-25 1.7e-24 7.9e-25
5 NAcc gene expression LOC102548791 0.17 0.08 0.0e+00 0.16 0.19 0.19 0.19 2.7e-18 2.0e-21 1.2e-21 1.4e-21
6 OFC gene expression LOC102548791 0.19 0.12 1.5e-03 0.07 0.09 0.07 0.06 8.9e-03 4.5e-03 1.0e-02 1.6e-02
7 pVTA gene expression LOC102548791 0.16 0.1 3.5e-05 0.08 0.11 0.1 0.1 1.9e-04 2.5e-05 4.5e-05 5.8e-05
8 Adipose gene expression LOC102548791 0.22 0.09 0.0e+00 0.18 0.18 0.18 0.18 3.0e-19 1.5e-19 8.0e-20 1.3e-19
9 BLA gene expression LOC102548791 0.28 0.16 1.5e-06 0.02 0.06 0.04 0.06 2.4e-02 2.2e-04 2.6e-03 3.8e-04
10 LHb gene expression LOC102548791 0.61 0.17 1.8e-09 0.18 0.32 0.33 0.3 3.6e-05 2.4e-08 1.6e-08 5.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.40.61.6-0.9-1.3-0.7-1.10.8-0.7-0.80.6-0.1-0.4
Area under the delay curve2.82.94.21.71.61.71.7-1.71.81.7-2.01.7-1.3
BMI with tail1.55.010.8-1.7-1.0-2.1-1.42.3-2.0-2.12.2-3.33.2
BMI without tail1.12.32.9-1.5-1.5-1.6-1.51.7-1.5-1.71.4-1.61.1
Body weight0.10.62.20.61.50.20.9-0.40.50.1-0.5-1.10.9
Weight adjusted by age0.20.20.60.40.20.40.3-0.30.50.3-0.60.4-0.8
Bone surface2.23.89.81.70.81.91.1-1.91.81.7-1.92.6-3.1
Bone volume0.61.04.80.6-0.20.70.0-0.80.70.6-0.71.5-2.2
Breakpoint value in progressive ratio session0.30.31.2-0.2-0.7-0.2-0.70.5-0.4-0.40.5-0.2-1.1
Number of licking bursts0.10.10.40.20.60.20.2-0.20.20.2-0.30.10.0
Context. condit. distance diff. score0.20.20.60.50.20.50.2-0.20.40.4-0.30.6-0.7
Locomotion velocity, session 10.91.02.01.01.40.91.3-1.11.01.0-1.00.60.3
Locomotion distance, session 12.32.93.5-1.9-1.5-1.9-1.61.6-1.7-1.81.6-1.71.6
Locomotion velocity, session 20.60.70.9-0.9-0.8-0.9-0.80.7-0.9-0.80.8-0.80.7
Locomotion distance, session 25.07.08.4-2.9-2.4-2.9-2.62.6-2.7-2.82.5-2.62.5
Locomotion velocity, session 30.30.40.60.60.70.60.8-0.70.60.7-0.70.60.2
Locomotion distance, session 30.91.02.1-0.9-0.5-1.0-0.61.0-0.9-0.91.0-1.31.5
Stereotopy head waving bouts, day 31.01.21.91.21.01.21.0-1.11.01.1-0.90.9-1.4
Stereotopy head waving duration, day 31.61.93.51.41.01.51.1-1.31.31.4-1.21.4-1.9
Locomotion velocity, session 70.20.20.50.40.20.40.4-0.40.60.4-0.70.7-0.4
Locomotion distance, session 71.62.03.3-1.5-1.8-1.5-1.71.5-1.4-1.61.1-1.00.6
Stereotopy head waving bouts, day 72.52.83.61.91.61.91.6-1.71.61.8-1.31.6-1.6
Stereotopy head waving duration, day 74.85.97.12.62.32.72.4-2.52.42.6-2.12.4-2.2
Locomotion velocity, session 81.72.03.01.41.11.41.2-1.41.51.4-1.51.7-1.3
Locomotion distance, session 82.13.14.0-1.9-1.9-1.9-2.01.9-1.8-1.91.7-1.41.1
Degree of sensitization distance0.60.62.0-0.8-1.4-0.7-1.20.6-0.6-0.80.30.3-0.6
Degree of sensitization stereotypy1.11.21.51.21.11.21.1-1.11.11.2-0.81.1-0.9
Conditioned locomotion0.20.20.3-0.4-0.5-0.4-0.60.3-0.4-0.50.4-0.2-0.4
Cocaine response after cond. corrected0.00.00.00.20.20.10.1-0.10.10.10.0-0.1-0.1
Cocaine response after cond. not corrected0.20.20.20.50.50.40.4-0.50.50.4-0.50.4-0.3
Cocaine response before conditioning0.60.71.50.70.60.70.6-0.80.90.8-1.11.2-0.6
Saline control response1.41.93.01.21.21.31.4-1.51.41.4-1.71.7-0.4
Bone: connectivity density0.20.20.8-0.5-0.9-0.3-0.70.4-0.2-0.3-0.00.5-0.5
Bone: cortical apparent density3.34.45.7-2.1-1.7-2.2-1.82.1-2.1-2.12.2-2.42.1
Bone: cortical area0.40.62.30.91.50.61.0-0.80.60.6-0.4-0.50.2
Bone: cortical porosity2.02.22.61.51.51.51.5-1.61.51.5-1.41.3-1.1
Bone: cortical porosity2.83.13.61.91.71.91.8-1.91.81.8-1.71.7-1.4
Bone: cortical thickness2.23.612.7-1.20.3-1.6-0.41.2-1.5-1.51.6-3.23.6
Bone: cortical thickness1.41.66.8-0.80.2-1.0-0.30.6-0.9-0.91.0-2.12.6
Bone: cortical tissue density3.34.45.5-2.1-1.7-2.2-1.92.1-2.2-2.12.2-2.32.1
Condit. Reinf. active minus inactive responses0.00.00.2-0.2-0.4-0.1-0.30.1-0.2-0.00.20.30.1
Condit. Reinf. active-inactive response ratio0.10.20.7-0.1-0.60.0-0.4-0.0-0.10.00.00.6-0.8
Condit. Reinf. active responses0.20.20.4-0.5-0.6-0.4-0.50.3-0.5-0.30.4-0.10.6
Condit. Reinf. inactive responses0.40.51.3-0.7-0.5-0.7-0.50.6-0.6-0.60.6-0.51.2
Incentive salience index mean0.00.00.20.0-0.20.2-0.0-0.20.00.20.00.5-0.2
Condit. Reinf. lever presses0.00.10.1-0.3-0.3-0.2-0.30.1-0.3-0.10.40.00.0
Condit. Reinf. active minus inactive responses1.31.62.11.21.11.21.1-1.21.31.3-1.41.4-1.3
Condit. Reinf. active-inactive response ratio0.70.81.10.90.80.90.9-0.91.00.9-1.10.9-0.5
Condit. Reinf. active responses0.10.20.90.2-0.00.30.0-0.30.30.2-0.40.7-0.9
Condit. Reinf. inactive responses0.20.30.7-0.6-0.8-0.5-0.80.5-0.5-0.50.5-0.0-0.3
Condit. Reinf. lever presses0.30.41.0-0.7-1.0-0.6-0.90.5-0.6-0.60.40.1-0.4
Condit. Reinf. lever reinforcers received0.10.10.6-0.2-0.5-0.1-0.40.2-0.1-0.20.00.3-0.8
Conditioned reinforcement - actives0.80.81.2-1.0-0.6-1.0-1.00.8-0.9-1.10.8-1.00.4
Conditioned reinforcement - inactives0.10.10.20.30.30.30.4-0.40.30.3-0.10.1-0.3
Conditioned locomotion0.91.11.7-1.1-0.6-1.2-1.21.1-1.0-1.30.9-1.20.4
Patch foraging indifference point 0 sec1.01.62.9-1.3-1.7-1.2-1.51.3-1.3-1.21.4-0.70.1
Patch foraging indifference point AUC0.20.20.5-0.6-0.7-0.5-0.50.5-0.4-0.40.10.00.6
Delay disc. indifference point, 0s delay1.92.12.91.51.21.51.7-1.61.61.6-1.71.2-0.4
Delay disc. indifference point, 16s delay0.10.10.1-0.2-0.2-0.2-0.40.3-0.2-0.20.00.1-0.3
Delay disc. indifference point, 2s delay1.21.42.61.20.41.21.2-1.21.31.1-1.61.1-0.9
Delay disc. indifference point, 24s delay0.00.00.20.10.40.10.1-0.20.10.1-0.20.2-0.3
Delay disc. indifference point, 4s delay2.93.04.81.81.11.81.8-1.81.91.8-2.21.7-1.1
Delay disc. indifference point, 8s delay6.97.18.92.82.52.82.7-2.72.82.7-3.02.6-2.1
Indifference point function ln k1.41.93.9-1.2-0.8-1.3-1.11.3-1.5-1.41.8-2.01.0
Indifference point function log k1.41.93.9-1.2-0.8-1.3-1.11.3-1.5-1.41.8-2.01.0
Patch foraging total patch changes 0 sec1.52.44.1-1.7-2.0-1.5-1.81.6-1.7-1.51.7-1.00.3
Patch foraging total patch changes 12 sec2.12.74.2-1.8-2.0-1.7-1.81.7-1.7-1.61.5-1.01.2
Patch foraging total patch changes 18 sec0.70.93.1-1.0-1.8-0.7-1.31.0-0.8-0.70.70.3-0.7
Patch foraging total patch changes 24 sec0.60.82.00.70.20.90.5-0.80.70.9-0.71.4-1.4
Patch foraging total patch changes 6 sec1.42.13.0-1.6-1.7-1.5-1.61.6-1.5-1.41.4-1.01.1
Patch foraging time to switch 0 sec0.30.50.60.80.70.80.7-0.60.80.7-0.70.7-0.5
Patch foraging water rate 0 sec0.20.30.5-0.7-0.7-0.7-0.70.5-0.6-0.70.4-0.30.2
Patch foraging water rate 12 sec2.23.35.0-1.8-1.5-1.8-1.71.9-2.0-1.82.1-2.21.2
Patch foraging water rate 18 sec0.50.71.0-0.9-1.0-0.8-1.01.0-0.9-0.90.8-0.70.2
Patch foraging water rate 24 sec1.52.13.6-1.5-1.9-1.4-1.71.7-1.5-1.51.4-0.90.2
Patch foraging water rate 6 sec0.81.22.5-1.0-0.6-1.1-0.81.0-1.1-1.11.1-1.61.4
Seeking ratio, delayed vs. immediate footshock0.10.10.30.10.20.00.3-0.10.20.1-0.50.00.5
Distance traveled before self-admin1.92.02.41.51.41.51.5-1.51.51.5-1.41.5-0.8
Distance traveled after self-admin0.91.02.3-1.0-1.5-0.9-1.31.2-1.0-1.00.8-0.3-0.3
Extensor digitorum longus weight1.87.18.0-2.8-2.6-2.8-2.72.6-2.8-2.82.8-2.72.1
Bone: elastic displacement2.83.25.3-1.8-1.2-1.8-1.41.6-1.8-1.71.8-2.22.3
Bone: elastic work0.50.62.1-0.50.1-0.7-0.20.5-0.7-0.70.8-1.51.3
Bone: endosteal estimation1.83.915.01.70.51.80.8-1.71.61.5-1.52.5-3.9
Bone: endosteal perimeter5.912.225.83.42.43.62.6-3.53.33.3-3.24.0-5.1
Epididymis fat weight0.20.61.7-0.5-0.3-0.7-0.50.7-0.6-0.80.7-1.31.0
Delta time in closed arm before/after self-admin1.31.21.91.10.91.11.0-0.91.21.1-1.41.3-1.2
Delta time in open arm before/after self-admin0.70.70.9-1.0-0.9-0.9-0.90.6-0.9-0.80.9-0.50.7
Diff in mean of infusions in LGA sessions0.40.43.20.5-0.10.50.1-0.30.40.3-0.30.6-1.8
Delay discount exponential model param3.13.34.5-1.9-1.6-1.8-1.81.8-1.9-1.82.1-1.81.5
Extinction: sum of active levers before priming0.40.40.7-0.5-0.5-0.5-0.50.6-0.7-0.50.8-0.70.5
Active lever presses in extinction session 60.20.20.3-0.4-0.5-0.4-0.50.6-0.3-0.50.4-0.4-0.2
Bone: final force0.40.61.60.81.30.71.0-0.70.70.7-0.7-0.10.2
Bone: final moment0.40.61.60.81.30.71.0-0.70.70.7-0.7-0.10.1
Food consumed during 24 hour testing period0.91.12.40.80.71.00.7-1.10.91.0-1.11.5-1.3
Glucose0.30.51.2-0.6-0.3-0.7-0.50.6-0.7-0.70.8-1.10.9
Heart weight0.81.13.0-0.8-0.4-1.0-0.61.0-1.0-1.01.3-1.71.2
Delay discount hyperbolic model param2.93.14.5-1.8-1.5-1.8-1.71.8-1.9-1.72.1-1.71.4
Intermittent access intake day 1-15 change0.80.81.20.80.80.90.9-1.10.90.9-0.80.9-0.3
Intermittent access intake escalation0.80.81.30.80.70.80.8-1.00.90.9-0.91.1-0.6
Intermittent access intake escalation 20.50.51.20.51.10.50.6-0.80.70.5-1.00.6-0.2
Intermitt. access day 1 inactive lever presses1.92.02.81.51.31.51.3-1.51.31.5-1.01.5-1.7
Intermitt. access day 15 inactive lever presses0.10.10.2-0.3-0.3-0.2-0.30.1-0.2-0.20.20.00.5
Intermitt. access escalation Index1.21.01.91.00.71.10.8-0.90.91.1-0.91.4-1.1
Intermittent access day 1 total infusions0.40.50.8-0.5-0.8-0.5-0.60.8-0.7-0.60.9-0.8-0.0
Intermittent access day 15 total infusions0.10.10.30.2-0.10.30.1-0.20.20.3-0.20.5-0.5
Intermittent access terminal intake (last 3 days)0.20.20.60.40.00.50.3-0.40.40.4-0.30.5-0.8
Intermittent access total infusions0.10.10.30.0-0.40.0-0.20.1-0.1-0.00.30.0-0.6
Intermittent access day 1 locomotion0.80.81.3-0.9-0.4-1.0-1.01.1-0.9-1.10.9-0.90.1
Intermittent access day 15 total locomotion0.00.00.1-0.00.2-0.1-0.00.1-0.0-0.20.1-0.4-0.4
Intermittent access total locomotion0.40.50.7-0.7-0.2-0.8-0.70.8-0.7-0.80.7-0.8-0.0
Intermittent access standard deviation2.32.44.21.82.11.71.8-1.61.61.6-1.41.0-0.6
Left kidney weight1.74.88.12.52.82.22.6-2.22.32.1-2.11.1-1.3
Right kidney weight0.51.43.51.31.91.11.5-1.21.21.1-1.10.2-0.3
Cocaine induced anxiety1.82.14.01.32.01.31.4-1.41.41.4-1.61.4-0.8
Post-drug Anxiety0.60.71.20.71.10.70.6-0.60.80.8-1.01.1-0.4
Baseline Anxiety0.40.40.5-0.5-0.7-0.5-0.60.7-0.6-0.50.7-0.60.6
Tail length0.51.43.10.90.70.90.8-1.11.30.9-1.61.5-1.8
Length with tail1.86.58.72.63.02.42.7-2.72.72.4-2.91.9-2.0
Length without tail1.73.68.02.12.81.92.4-2.01.91.8-1.80.5-0.3
Times rat made contact with spout0.00.00.2-0.2-0.2-0.1-0.30.1-0.1-0.10.10.2-0.5
Lifetime Intake0.00.00.20.1-0.20.1-0.10.1-0.1-0.00.3-0.1-0.4
Liver weight, left1.72.83.61.91.91.81.8-1.71.71.7-1.51.2-1.1
Liver weight, right0.50.81.81.01.40.91.2-0.91.00.8-0.90.20.1
Locomotor activity0.00.00.0-0.1-0.0-0.2-0.1-0.0-0.1-0.20.0-0.20.1
Locomotor testing distance0.10.11.00.2-0.00.2-0.0-0.20.20.1-0.40.3-1.0
Locomotor testing rearing0.20.30.8-0.7-0.9-0.6-0.80.4-0.5-0.60.4-0.0-0.1
Locomotion in novel chamber0.30.31.50.2-0.40.4-0.1-0.40.30.4-0.41.2-0.9
Locomotion in novel chamber post-restriction0.50.62.10.60.10.70.3-0.70.60.7-0.51.2-1.4
Fecal boli incidents, locomotor time 11.01.01.5-1.0-1.1-1.0-1.21.0-1.1-1.21.1-0.90.3
Change in fecal boli incidents, locomotor task0.40.40.6-0.6-0.4-0.6-0.50.7-0.6-0.60.7-0.70.7
Time >=10cm from walls, locomotor time 10.60.61.50.60.40.80.5-0.90.70.8-0.61.2-1.1
Bouts of movement, locomotor time 10.70.81.5-0.8-0.2-0.8-0.70.7-0.9-0.81.2-1.11.2
Total resting periods, locomotor time 10.80.91.7-0.9-0.4-0.9-0.80.9-1.0-0.91.3-1.11.2
Rest time, locomotor task time 10.30.40.9-0.4-0.2-0.4-0.30.8-0.5-0.50.6-0.90.9
Distance moved, locomotor task time 10.30.30.70.30.00.40.3-0.50.50.5-0.60.8-0.8
Vertical activity count, locomotor time 10.10.10.1-0.4-0.3-0.4-0.40.1-0.2-0.3-0.00.1-0.1
Time >=10cm from walls, locomotor time 20.20.20.3-0.5-0.3-0.5-0.30.3-0.4-0.40.4-0.50.5
Bouts of movement, locomotor time 20.10.10.40.20.30.20.1-0.00.10.20.00.2-0.6
Total resting periods, locomotor time 20.10.10.50.30.40.30.1-0.00.20.2-0.10.3-0.7
Rest time, locomotor task time 20.10.20.50.50.30.50.2-0.10.40.3-0.40.4-0.7
Distance moved, locomotor task time 20.10.20.7-0.3-0.2-0.40.10.2-0.2-0.30.1-0.70.9
Vertical activity count, locomotor time 20.20.30.8-0.5-0.2-0.6-0.30.3-0.4-0.60.4-0.90.6
Light reinforcement 11.42.53.1-1.7-1.7-1.7-1.61.8-1.6-1.61.5-1.21.3
Light reinforcement 20.00.00.4-0.00.2-0.10.20.20.00.0-0.2-0.10.6
Bone: marrow area1.84.015.01.70.51.90.8-1.81.71.6-1.62.6-3.9
Bone: maximum diameter4.98.911.33.22.93.12.8-3.23.02.9-2.82.6-3.4
Bone: maximum force0.20.30.80.70.90.50.7-0.40.50.4-0.4-0.2-0.1
Bone: maximum moment0.20.30.70.60.90.50.7-0.40.50.4-0.3-0.2-0.3
Mean time between licks in bursts0.00.10.5-0.1-0.1-0.1-0.00.1-0.1-0.10.2-0.30.7
Mean num. licks in bursts0.50.61.1-0.8-1.0-0.8-0.90.8-0.8-0.80.8-0.50.0
Cd content in liver2.83.14.2-1.7-1.3-1.7-1.51.6-1.8-1.71.9-2.12.0
Co content in liver1.21.42.0-1.2-1.4-1.1-1.31.1-1.3-1.21.4-1.00.6
Cu content in liver0.00.00.1-0.10.0-0.2-0.0-0.1-0.2-0.10.2-0.4-0.0
Fe content in liver0.60.71.90.70.20.90.4-0.90.70.8-0.61.4-1.3
K content in liver0.20.20.50.30.30.40.3-0.40.40.5-0.40.7-0.5
Mg content in liver1.01.11.7-1.2-1.3-1.1-1.21.1-1.1-1.01.1-0.50.4
Mn content in liver1.51.72.31.31.51.31.4-1.31.41.3-1.51.1-0.7
Na content in liver1.21.31.61.01.01.11.0-1.21.11.2-1.21.3-1.2
Rb content in liver1.62.02.3-1.5-1.5-1.5-1.41.5-1.3-1.51.1-1.21.5
Se content in liver0.30.41.10.30.10.50.3-0.60.50.5-0.71.1-0.7
Sr content in liver0.20.20.5-0.30.0-0.3-0.10.3-0.3-0.30.4-0.70.7
Zn content in liver0.40.40.70.70.80.70.7-0.80.50.7-0.40.3-0.5
Bone: minimum diameter2.03.66.61.91.62.01.6-2.11.81.9-1.61.9-2.6
Time in familiar zone, hab. session 10.30.30.6-0.5-0.5-0.5-0.50.5-0.6-0.40.8-0.40.6
Time in novel zone, hab. session 11.01.01.51.01.01.01.1-1.01.11.0-1.20.9-0.7
Total zone transitions, hab. session 11.31.92.5-1.6-1.4-1.5-1.51.3-1.4-1.51.3-1.21.1
Total locomotion distance, hab. session 11.31.82.3-1.5-1.3-1.5-1.41.3-1.4-1.51.3-1.31.0
Locomotion velocity, hab. session 12.02.83.5-1.9-1.6-1.9-1.71.6-1.7-1.81.6-1.61.2
Time in familiar zone, hab. session 20.20.20.4-0.4-0.4-0.4-0.40.6-0.5-0.50.5-0.40.3
Time in novel zone, hab. session 20.40.40.50.60.50.70.6-0.60.60.7-0.50.7-0.6
Total zone transitions, hab. session 25.16.57.9-2.8-2.7-2.8-2.82.6-2.6-2.72.4-2.21.8
Total locomotion distance, hab. session 25.77.68.8-3.0-2.8-3.0-2.82.8-2.8-2.92.7-2.62.0
Locomotion velocity, hab. session 25.37.18.4-2.9-2.6-2.9-2.82.7-2.7-2.82.6-2.52.0
Novel to familiar place preference ratio2.32.43.4-1.7-1.9-1.6-1.81.6-1.6-1.61.6-1.20.6
Novelty place preference1.71.72.6-1.4-1.6-1.3-1.51.4-1.4-1.31.4-0.90.4
Time in novel zone, NPP test2.12.23.2-1.6-1.8-1.5-1.71.5-1.5-1.51.5-1.10.6
Total zone transitions, NPP test3.14.45.5-2.3-2.1-2.3-2.22.1-2.2-2.22.0-1.81.7
Total locomotion distance, NPP test7.810.712.4-3.5-3.2-3.5-3.33.3-3.4-3.43.3-3.12.6
Locomotion velocity, NPP test6.49.110.7-3.3-2.9-3.3-3.13.0-3.1-3.23.0-2.92.3
Intraocular pressure0.70.92.3-0.8-1.5-0.7-1.31.0-0.9-0.91.0-0.2-0.7
Delta distance traveled before/after self-admin3.23.54.6-2.0-2.1-2.0-2.12.0-1.9-2.01.8-1.50.7
Delta ambulatory time before/after self-admin3.13.44.9-2.0-2.2-1.9-2.22.0-1.9-1.91.7-1.40.5
Parametrial fat weight0.00.00.2-0.00.1-0.1-0.00.2-0.0-0.20.0-0.40.2
Pavlov. Cond. lever latency0.20.30.9-0.4-0.9-0.3-0.70.6-0.4-0.40.30.2-0.5
Pavlov. Cond. magazine entry latency2.83.64.01.91.91.91.9-2.01.92.0-1.91.8-1.8
Pavlov. Cond. change in total contacts1.01.11.7-1.0-0.7-1.1-0.91.0-1.1-1.01.1-1.31.0
Pavlov. Cond. index score1.11.42.11.21.41.21.3-1.31.21.2-1.10.8-0.8
Pavlov. Cond. latency score1.41.82.91.41.71.31.6-1.51.31.4-1.30.9-0.7
Pavlov. Cond. lever contacts0.10.10.5-0.20.2-0.30.00.1-0.3-0.20.4-0.60.7
Pavlov. Cond. magazine entry number2.63.33.8-1.9-1.9-1.9-1.91.9-1.8-1.91.7-1.51.6
Pavlov. Cond. intertrial magazine entries1.51.82.7-1.4-1.6-1.3-1.51.4-1.4-1.31.3-0.81.2
Pavlov. Cond. lever-magazine prob. diff.0.80.91.41.01.21.01.1-1.10.91.0-0.90.7-0.7
Pavlov. Cond. response bias0.91.01.51.11.21.01.1-1.11.01.1-0.90.7-0.8
Pavlov. Cond. lever latency0.50.71.80.81.30.71.2-0.70.70.8-0.7-0.10.7
Pavlov. Cond. magazine entry latency1.31.52.3-1.1-1.5-1.1-1.41.3-1.3-1.21.5-0.90.2
Pavlov. Cond. change in total contacts1.01.42.6-1.2-1.6-1.1-1.51.2-1.2-1.21.3-0.5-0.1
Pavlov. Cond. index score0.70.92.0-1.0-1.4-0.8-1.30.9-1.0-0.91.1-0.3-0.3
Pavlov. Cond. latency score0.50.61.5-0.7-1.2-0.6-1.10.7-0.8-0.70.9-0.1-0.5
Pavlov. Cond. lever contacts0.30.51.3-0.7-1.1-0.5-1.00.4-0.5-0.50.40.4-0.7
Pavlov. Cond. magazine entry number1.62.03.11.41.81.31.6-1.51.51.4-1.70.9-0.2
Pavlov. Cond. intertrial magazine entries1.41.93.41.10.81.10.9-1.51.31.2-1.71.8-1.8
Pavlov. Cond. lever-magazine prob. diff.0.81.02.3-1.0-1.5-0.9-1.41.0-1.0-1.01.2-0.3-0.3
Pavlov. Cond. response bias0.60.91.8-1.0-1.3-0.9-1.20.8-1.0-0.91.0-0.3-0.2
Time in closed arm before self-admin0.40.52.1-0.4-0.0-0.6-0.20.4-0.5-0.50.5-0.91.4
Time in closed arm after self-admin0.80.91.31.11.01.11.0-0.81.01.0-0.90.6-0.7
Time in open arm before self-admin0.40.50.80.70.90.70.7-0.60.70.6-0.70.5-0.5
Time in open arm after self-admin0.10.20.3-0.5-0.5-0.4-0.50.3-0.4-0.40.4-0.10.0
Bone: periosteal estimation1.32.86.31.81.41.71.3-1.81.61.5-1.41.5-2.5
Bone: periosteal perimeter3.55.97.32.62.72.52.4-2.72.42.4-2.21.8-2.4
Bone: post-yield work0.71.01.8-1.0-1.4-0.9-1.21.1-1.0-1.01.1-0.6-0.3
Progressive ratio test 1 active lever presses0.10.10.4-0.1-0.0-0.1-0.40.1-0.1-0.10.20.2-0.7
Progressive ratio test 1 breakpoint0.10.10.2-0.2-0.1-0.2-0.40.2-0.3-0.20.40.1-0.5
Progressive ratio test 1 inactive lever presses0.30.40.60.60.30.70.5-0.60.60.7-0.40.7-0.8
Progressive ratio test 2 active lever presses0.20.20.4-0.4-0.3-0.5-0.60.5-0.4-0.60.4-0.5-0.3
Progressive ratio test 2 breakpoint0.20.20.4-0.5-0.2-0.5-0.60.5-0.4-0.60.4-0.6-0.1
Progressive ratio test 2 inactive lever presses0.00.00.10.1-0.10.00.1-0.00.10.0-0.1-0.1-0.2
Incentive Sensitization - Responses0.10.10.40.30.60.20.3-0.20.20.10.1-0.2-0.3
Incentive Sensitization - Breakpoint0.10.10.50.40.70.40.4-0.40.30.3-0.0-0.0-0.4
Sum of active levers in priming session hrs 5-60.10.10.70.0-0.40.1-0.30.1-0.10.00.30.2-0.8
Progressive ratio0.50.60.9-0.6-0.9-0.6-0.80.9-0.8-0.80.9-0.8-0.0
Food seeking constrained by brief footshock0.00.00.10.30.20.30.3-0.10.20.20.0-0.1-0.0
Seeking ratio, punishment vs. effort0.70.81.10.91.00.91.0-1.00.91.0-0.90.9-0.4
Retroperitoneal fat weight0.20.81.21.10.91.00.9-0.91.00.8-0.80.7-0.8
Reaction time number correct1.21.83.7-1.5-1.9-1.3-1.71.4-1.3-1.31.1-0.40.3
Reaction time mean minus median0.20.30.70.50.80.50.7-0.50.40.5-0.20.00.1
Reaction time mean minus median AUC1.01.21.91.11.41.11.3-1.21.11.2-1.00.8-0.5
Reaction time num false alarms0.10.20.3-0.4-0.5-0.4-0.50.5-0.4-0.40.3-0.3-0.1
Reaction time num false alarms AUC0.20.30.5-0.5-0.7-0.6-0.70.6-0.5-0.60.3-0.4-0.1
Reaction time trials correct on left1.21.83.7-1.5-1.9-1.3-1.71.4-1.3-1.31.1-0.40.3
Reaction time trials on left1.21.73.6-1.5-1.9-1.3-1.71.3-1.3-1.31.1-0.40.3
Reaction time mean0.00.00.00.00.10.00.1-0.00.00.00.1-0.20.1
Reaction time mean AUC0.10.10.2-0.2-0.2-0.3-0.20.3-0.3-0.30.4-0.50.3
Median of all reaction times0.00.00.0-0.1-0.1-0.1-0.10.1-0.1-0.10.1-0.20.1
Reaction time omissions0.60.91.41.01.20.91.0-1.00.90.9-0.90.6-0.6
Reaction time false alarm rate0.00.10.10.30.40.20.3-0.20.20.2-0.3-0.1-0.3
Reaction time premature initiation rate3.85.15.7-2.3-2.0-2.4-2.22.4-2.3-2.32.1-2.32.2
Reaction time premature initiations5.37.48.7-2.9-2.9-2.9-3.02.9-2.8-2.92.5-2.42.0
Std. dev. reaction times0.00.00.1-0.00.1-0.10.10.1-0.1-0.00.3-0.30.3
Reaction time trials completed1.21.73.6-1.5-1.9-1.3-1.71.3-1.3-1.31.1-0.40.3
Reaction time trials AUC1.52.24.4-1.7-2.1-1.5-1.91.6-1.5-1.51.3-0.60.5
Run reversals in cocaine runway, females0.10.10.3-0.1-0.3-0.0-0.20.2-0.2-0.10.5-0.00.2
Run reversals in cocaine runway, males0.40.41.5-0.40.0-0.6-0.30.7-0.4-0.70.4-1.20.8
Latency to leave start box in cocaine runway0.80.91.2-0.9-0.9-1.0-0.91.1-1.0-1.01.0-1.00.7
Latency to leave start box in cocaine runway, F0.60.60.9-0.8-0.8-0.8-0.80.9-0.8-0.80.8-0.70.7
Latency to leave start box in cocaine runway, M1.71.62.0-1.3-1.2-1.3-1.31.3-1.3-1.41.3-1.40.8
Std. dev. time between licks in bursts0.30.40.8-0.8-0.7-0.7-0.90.6-0.6-0.70.4-0.10.2
Total sessions with >9 infusions0.10.10.30.50.40.40.4-0.30.30.3-0.0-0.1-0.5
Short access day 1 total inactive lever presses0.10.20.30.50.20.50.4-0.40.50.4-0.40.3-0.3
Short access day 10 total inactive lever presses1.11.21.61.20.91.21.2-1.21.11.3-1.11.1-0.3
Short access day 1 total infusions0.10.10.20.50.30.50.4-0.40.30.4-0.00.1-0.4
Short access day 10 total infusions0.40.41.80.70.30.70.4-0.50.50.6-0.10.6-1.3
Short access total infusions0.10.10.3-0.1-0.2-0.2-0.20.3-0.3-0.20.5-0.4-0.0
Short access day 1 locomotion0.10.10.20.30.40.20.4-0.20.30.2-0.2-0.30.3
Short access day 10 total locomotion0.10.10.20.30.50.20.3-0.20.20.2-0.1-0.2-0.3
Short access total locomotion0.10.20.70.10.6-0.10.30.1-0.0-0.10.3-0.80.4
One hour access (0.3 mA shock)0.20.30.5-0.5-0.5-0.5-0.70.6-0.5-0.60.6-0.3-0.1
Compulsive drug intake0.90.91.2-0.9-0.7-1.0-0.91.0-0.9-1.01.1-1.00.8
One hour access (shock baseline)0.20.20.50.40.30.40.2-0.40.40.3-0.50.6-0.7
Social response proportion0.90.91.4-0.9-0.7-1.0-0.81.0-0.9-1.00.9-1.21.2
Social responses0.20.21.6-0.30.0-0.4-0.10.2-0.3-0.30.2-0.51.3
Social time1.31.72.1-1.3-1.0-1.3-1.11.2-1.3-1.31.4-1.41.4
Soleus weight1.23.55.5-1.8-1.3-1.9-1.51.8-1.8-1.81.9-2.22.3
Bone: stiffness0.40.71.71.01.30.81.1-0.80.80.8-0.70.1-0.0
Tibialis anterior weight0.51.62.2-1.3-1.0-1.3-1.21.2-1.3-1.31.5-1.41.2
Time to tail flick, vehicle, before self-admin0.60.61.9-0.8-0.3-0.8-0.50.4-0.8-0.70.8-0.91.4
Time to tail flick, vehicle, after self-admin0.20.20.7-0.00.1-0.10.10.4-0.3-0.10.7-0.90.8
Time to tail flick, test, before self-admin0.10.10.30.10.10.20.1-0.50.30.2-0.50.5-0.4
Time to tail flick, test, after self-admin0.40.50.90.80.90.70.7-0.70.70.6-0.60.3-0.5
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.1-0.6-0.1-0.40.5-0.3-0.20.5-0.2-0.4
Delta time to tail flick, test, before/after SA0.30.20.70.60.80.50.7-0.20.40.4-0.2-0.20.2
Tibia length11.031.043.26.16.65.76.3-5.85.85.6-5.84.0-3.1
Ambulatory time before self-admin2.52.63.11.71.71.71.8-1.71.71.7-1.51.5-1.1
Ambulatory time after self-admin0.30.30.7-0.5-0.9-0.4-0.70.7-0.4-0.50.3-0.0-0.5
Bone: tissue strength1.71.62.3-1.3-1.4-1.3-1.41.5-1.3-1.31.4-1.20.3
Total heroin consumption1.31.53.11.31.11.31.1-1.21.11.2-1.00.9-1.7
Bone: trabecular number0.10.10.4-0.1-0.40.1-0.2-0.10.10.1-0.20.6-0.6
Bone: trabecular spacing0.00.00.10.30.30.30.3-0.20.20.2-0.10.0-0.0
Bone: trabecular thickness0.30.30.7-0.7-0.8-0.6-0.80.4-0.6-0.60.5-0.2-0.1
Bone: trabecular tissue density0.10.20.50.40.70.20.5-0.40.40.2-0.4-0.10.3
Water consumed over 24 hours0.00.00.2-0.00.20.10.1-0.10.10.2-0.20.5-0.1
Number of responses in last shaping day0.80.81.41.11.01.01.2-1.11.00.9-0.80.4-0.2