Hub : Genes

LOC102548046

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	LOC102548046	0.14	0.07	0.0e+00	0.17	0.17	0.17	0.17	6.6e-19	9.9e-19	6.4e-19	7.5e-19
2	Liver	mRNA stability	LOC102548046	0.02	0.01	8.4e-03	0.01	0.01	-0	0.01	5.3e-02	5.2e-02	3.8e-01	6.7e-02
3	Brain	gene expression	LOC102548046	0.04	0.04	1.0e-03	0.02	0.03	0.03	0.02	2.5e-03	1.1e-03	1.3e-03	3.2e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Bone: apparent density	1.1	1.9	2.6	-1.6	1.5	0.8
Area under the delay curve	1.1	1.3	1.6	1.1	-1.1	-1.2
BMI with tail	0.1	0.4	0.7	0.9	-0.6	0.2
BMI without tail	0.4	1.2	2.3	-0.7	0.9	1.5
Body weight	0.7	2.9	4.5	2.1	-1.8	-1.0
Weight adjusted by age	0.0	0.0	0.1	-0.1	0.1	-0.3
Bone surface	0.6	1.1	2.5	0.7	-0.6	-1.6
Bone volume	0.1	0.2	0.5	-0.0	0.2	-0.7
Breakpoint value in progressive ratio session	0.2	0.2	0.4	0.6	-0.0	-0.5
Number of licking bursts	0.0	0.1	0.1	0.3	-0.2	-0.1
Context. condit. distance diff. score	0.3	0.4	0.5	0.7	-0.5	-0.7
Locomotion velocity, session 1	0.6	0.6	1.0	0.5	-1.0	-0.8
Locomotion distance, session 1	3.0	3.8	4.2	-1.9	1.9	2.1
Locomotion velocity, session 2	0.7	0.8	1.0	-1.0	0.9	0.8
Locomotion distance, session 2	7.1	10.0	11.7	-3.4	3.0	3.0
Locomotion velocity, session 3	0.1	0.1	0.1	0.2	-0.4	-0.2
Locomotion distance, session 3	0.2	0.3	0.7	-0.1	0.3	0.8
Stereotopy head waving bouts, day 3	2.4	2.8	3.2	1.6	-1.6	-1.8
Stereotopy head waving duration, day 3	2.2	2.6	3.4	1.5	-1.5	-1.9
Locomotion velocity, session 7	0.0	0.0	0.1	-0.2	0.2	0.0
Locomotion distance, session 7	3.3	4.2	4.9	-2.0	2.2	1.9
Stereotopy head waving bouts, day 7	5.4	6.1	6.2	2.5	-2.4	-2.5
Stereotopy head waving duration, day 7	6.9	8.3	9.5	2.7	-2.8	-3.1
Locomotion velocity, session 8	0.6	0.7	1.4	0.5	-0.7	-1.2
Locomotion distance, session 8	2.8	4.1	4.6	-2.0	2.1	1.9
Degree of sensitization distance	3.5	3.6	4.6	-2.1	2.1	1.4
Degree of sensitization stereotypy	2.1	2.2	2.6	1.6	-1.5	-1.4
Conditioned locomotion	0.3	0.3	0.4	-0.5	0.6	0.5
Cocaine response after cond. corrected	0.2	0.2	0.2	0.5	-0.5	-0.5
Cocaine response after cond. not corrected	0.1	0.1	0.1	0.2	-0.3	-0.4
Cocaine response before conditioning	0.2	0.2	0.5	-0.7	0.4	0.0
Saline control response	0.2	0.3	0.7	-0.8	0.3	0.3
Bone: connectivity density	1.4	2.2	3.5	-1.9	1.6	0.8
Bone: cortical apparent density	1.7	2.4	2.8	-1.7	1.4	1.5
Bone: cortical area	3.5	5.4	6.2	2.5	-2.5	-2.0
Bone: cortical porosity	2.2	2.3	3.1	1.3	-1.5	-1.8
Bone: cortical porosity	3.4	3.7	4.6	1.7	-1.9	-2.1
Bone: cortical thickness	0.4	0.6	1.2	0.7	-1.1	0.3
Bone: cortical thickness	0.2	0.2	0.3	0.5	-0.5	0.4
Bone: cortical tissue density	1.8	2.5	2.9	-1.7	1.5	1.6
Condit. Reinf. active minus inactive responses	0.1	0.1	0.2	-0.5	0.4	0.2
Condit. Reinf. active-inactive response ratio	0.3	0.3	0.5	-0.7	0.5	-0.1
Condit. Reinf. active responses	0.6	0.8	0.9	-0.9	0.8	0.9
Condit. Reinf. inactive responses	0.8	1.0	1.6	-0.8	0.8	1.3
Incentive salience index mean	0.0	0.0	0.0	-0.2	0.1	0.0
Condit. Reinf. lever presses	0.1	0.2	0.3	-0.4	0.4	0.5
Condit. Reinf. active minus inactive responses	0.1	0.2	0.4	0.2	-0.4	-0.6
Condit. Reinf. active-inactive response ratio	0.1	0.1	0.2	0.2	-0.4	-0.4
Condit. Reinf. active responses	0.2	0.2	0.4	-0.6	0.5	0.2
Condit. Reinf. inactive responses	0.9	1.2	1.5	-1.2	1.2	0.9
Condit. Reinf. lever presses	1.2	1.7	2.1	-1.5	1.4	0.9
Condit. Reinf. lever reinforcers received	0.3	0.5	0.6	-0.8	0.8	0.4
Conditioned reinforcement - actives	0.5	0.8	1.3	-0.5	0.9	1.1
Conditioned reinforcement - inactives	0.0	0.0	0.1	0.2	-0.2	0.1
Conditioned locomotion	1.2	1.6	2.1	-1.0	1.3	1.4
Patch foraging indifference point 0 sec	1.1	2.1	2.5	-1.3	1.6	1.4
Patch foraging indifference point AUC	1.1	1.5	2.1	-1.4	1.2	1.0
Delay disc. indifference point, 0s delay	0.9	1.0	1.2	0.7	-1.1	-1.1
Delay disc. indifference point, 16s delay	0.1	0.1	0.2	-0.3	0.5	0.3
Delay disc. indifference point, 2s delay	0.4	0.4	0.5	0.7	-0.6	-0.6
Delay disc. indifference point, 24s delay	0.0	0.0	0.1	-0.3	0.1	-0.1
Delay disc. indifference point, 4s delay	1.4	1.5	1.7	1.1	-1.2	-1.3
Delay disc. indifference point, 8s delay	4.3	5.1	5.5	2.2	-2.2	-2.4
Indifference point function ln k	0.0	0.1	0.1	0.3	-0.1	0.3
Indifference point function log k	0.0	0.1	0.1	0.3	-0.1	0.3
Patch foraging total patch changes 0 sec	1.5	2.7	3.2	-1.5	1.8	1.7
Patch foraging total patch changes 12 sec	4.0	5.2	5.6	-2.2	2.3	2.4
Patch foraging total patch changes 18 sec	2.1	3.2	4.2	-1.7	2.0	1.6
Patch foraging total patch changes 24 sec	0.1	0.1	0.2	0.3	-0.2	-0.5
Patch foraging total patch changes 6 sec	2.1	3.2	3.3	-1.8	1.8	1.7
Patch foraging time to switch 0 sec	0.2	0.5	0.5	0.7	-0.7	-0.7
Patch foraging water rate 0 sec	0.6	1.3	1.6	-1.0	1.2	1.2
Patch foraging water rate 12 sec	0.3	0.6	1.0	-0.4	0.7	1.0
Patch foraging water rate 18 sec	0.3	0.4	0.6	-0.5	0.8	0.6
Patch foraging water rate 24 sec	1.7	2.3	2.9	-1.3	1.7	1.6
Patch foraging water rate 6 sec	0.2	0.3	0.6	-0.3	0.3	0.8
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.2	-0.4	0.1	0.1
Distance traveled before self-admin	0.3	0.4	0.6	0.6	-0.8	-0.5
Distance traveled after self-admin	1.3	1.6	2.3	-1.2	1.5	1.1
Extensor digitorum longus weight	1.4	5.4	7.3	-2.0	2.3	2.7
Bone: elastic displacement	1.5	1.8	2.4	-1.3	1.1	1.6
Bone: elastic work	0.2	0.3	0.5	0.6	-0.7	-0.3
Bone: endosteal estimation	1.2	2.7	4.2	1.7	-1.0	-2.1
Bone: endosteal perimeter	5.6	11.8	16.1	3.3	-2.9	-4.0
Epididymis fat weight	0.0	0.1	0.2	0.4	0.0	0.2
Delta time in closed arm before/after self-admin	0.0	0.0	0.0	-0.1	0.2	-0.1
Delta time in open arm before/after self-admin	0.8	0.8	1.0	-0.8	0.9	1.0
Diff in mean of infusions in LGA sessions	1.0	1.2	1.6	1.2	-0.7	-1.3
Delay discount exponential model param	1.5	1.7	2.0	-1.3	1.2	1.4
Extinction: sum of active levers before priming	0.1	0.1	0.1	-0.2	0.3	0.3
Active lever presses in extinction session 6	0.1	0.1	0.1	-0.2	0.3	0.4
Bone: final force	1.3	2.1	2.5	1.3	-1.6	-1.4
Bone: final moment	1.5	2.3	2.8	1.3	-1.7	-1.6
Food consumed during 24 hour testing period	0.1	0.1	0.2	-0.3	-0.1	-0.4
Glucose	0.6	1.0	1.4	1.2	-1.1	-0.6
Heart weight	0.6	1.0	1.7	1.3	-1.1	-0.2
Delay discount hyperbolic model param	1.5	1.7	1.9	-1.3	1.2	1.4
Intermittent access intake day 1-15 change	0.2	0.4	0.6	0.6	-0.7	-0.6
Intermittent access intake escalation	0.1	0.2	0.3	0.4	-0.6	-0.4
Intermittent access intake escalation 2	0.2	0.2	0.2	0.5	-0.5	-0.3
Intermitt. access day 1 inactive lever presses	0.2	0.7	0.8	0.8	-0.8	-0.9
Intermitt. access day 15 inactive lever presses	0.1	0.2	0.3	-0.5	0.5	0.5
Intermitt. access escalation Index	0.3	0.4	0.7	0.3	-0.5	-0.9
Intermittent access day 1 total infusions	0.0	0.1	0.1	0.3	0.2	0.4
Intermittent access day 15 total infusions	0.0	0.0	0.1	-0.1	0.2	0.3
Intermittent access terminal intake (last 3 days)	0.2	0.2	0.4	0.6	-0.4	-0.3
Intermittent access total infusions	0.1	0.1	0.2	0.4	-0.2	-0.1
Intermittent access day 1 locomotion	0.8	1.0	1.2	-0.9	1.1	1.1
Intermittent access day 15 total locomotion	0.0	0.0	0.1	0.1	0.0	0.4
Intermittent access total locomotion	0.1	0.2	0.3	-0.2	0.4	0.6
Intermittent access standard deviation	4.1	8.5	10.1	3.2	-2.9	-2.6
Left kidney weight	1.3	6.1	7.2	2.7	-2.5	-2.2
Right kidney weight	0.3	1.4	2.0	1.4	-1.3	-0.8
Cocaine induced anxiety	0.2	0.3	0.6	0.4	-0.8	-0.5
Post-drug Anxiety	0.0	0.0	0.1	0.1	-0.2	0.2
Baseline Anxiety	0.3	0.3	0.5	-0.4	0.7	0.5
Tail length	0.0	0.0	0.0	-0.0	0.1	-0.0
Length with tail	1.1	5.0	5.7	2.4	-2.3	-2.0
Length without tail	2.6	8.5	9.9	3.2	-3.0	-2.5
Times rat made contact with spout	0.3	0.3	0.4	-0.5	0.7	0.4
Lifetime Intake	0.1	0.1	0.2	0.5	-0.3	-0.2
Liver weight, left	1.5	2.5	2.6	1.6	-1.6	-1.5
Liver weight, right	1.2	2.0	2.2	1.4	-1.4	-1.5
Locomotor activity	0.1	0.1	0.2	-0.4	0.2	0.1
Locomotor testing distance	0.0	0.1	0.2	-0.3	0.4	-0.1
Locomotor testing rearing	0.8	1.6	2.3	-1.5	1.3	0.9
Locomotion in novel chamber	0.3	0.4	0.6	-0.8	0.8	0.2
Locomotion in novel chamber post-restriction	0.3	0.4	1.0	0.5	-0.3	-1.0
Fecal boli incidents, locomotor time 1	0.2	0.2	0.4	-0.2	0.6	0.5
Change in fecal boli incidents, locomotor task	0.0	0.0	0.0	-0.1	0.1	0.2
Time >=10cm from walls, locomotor time 1	0.1	0.1	0.3	-0.1	-0.1	-0.6
Bouts of movement, locomotor time 1	0.0	0.1	0.2	0.0	0.1	0.4
Total resting periods, locomotor time 1	0.1	0.1	0.3	-0.1	0.2	0.5
Rest time, locomotor task time 1	0.3	0.4	0.7	0.8	-0.7	-0.3
Distance moved, locomotor task time 1	0.1	0.2	0.4	-0.6	0.4	0.2
Vertical activity count, locomotor time 1	0.6	1.5	1.6	-1.1	1.3	1.2
Time >=10cm from walls, locomotor time 2	0.2	0.3	0.6	-0.8	0.4	0.5
Bouts of movement, locomotor time 2	0.2	0.2	0.3	0.6	-0.4	-0.5
Total resting periods, locomotor time 2	0.2	0.3	0.4	0.6	-0.4	-0.6
Rest time, locomotor task time 2	0.7	0.9	1.5	1.2	-0.7	-0.9
Distance moved, locomotor task time 2	0.4	0.4	0.7	-0.8	0.3	0.7
Vertical activity count, locomotor time 2	0.3	0.4	0.9	-0.4	0.5	0.9
Light reinforcement 1	2.0	4.8	6.0	-1.9	2.2	2.4
Light reinforcement 2	0.2	0.2	0.5	-0.2	0.4	0.7
Bone: marrow area	1.2	2.7	4.2	1.7	-1.0	-2.1
Bone: maximum diameter	9.0	16.9	18.3	4.2	-3.9	-4.3
Bone: maximum force	1.3	2.4	2.5	1.5	-1.6	-1.6
Bone: maximum moment	1.5	2.7	2.9	1.5	-1.7	-1.7
Mean time between licks in bursts	0.0	0.0	0.1	-0.2	-0.2	-0.3
Mean num. licks in bursts	0.5	0.8	1.0	-1.0	1.0	0.7
Cd content in liver	1.4	1.5	1.8	-1.1	1.3	1.4
Co content in liver	0.0	0.0	0.0	-0.1	0.1	0.0
Cu content in liver	0.1	0.1	0.1	0.3	-0.3	-0.3
Fe content in liver	0.0	0.1	0.2	0.0	0.1	-0.4
K content in liver	0.4	0.4	0.7	-0.9	0.5	0.2
Mg content in liver	2.9	3.0	4.2	-2.0	1.7	1.3
Mn content in liver	0.1	0.1	0.3	0.1	-0.4	-0.5
Na content in liver	0.1	0.1	0.2	-0.3	0.0	-0.4
Rb content in liver	1.9	2.2	2.6	-1.6	1.5	1.4
Se content in liver	1.0	1.1	1.6	-1.3	1.1	0.7
Sr content in liver	0.0	0.0	0.0	-0.1	0.0	0.1
Zn content in liver	0.1	0.1	0.2	0.4	-0.3	-0.1
Bone: minimum diameter	3.4	6.1	7.9	2.3	-2.3	-2.8
Time in familiar zone, hab. session 1	0.1	0.1	0.2	-0.1	0.2	0.4
Time in novel zone, hab. session 1	0.4	0.4	0.7	0.3	-0.6	-0.8
Total zone transitions, hab. session 1	2.2	3.1	4.0	-2.0	1.7	1.5
Total locomotion distance, hab. session 1	2.0	2.9	3.1	-1.8	1.7	1.7
Locomotion velocity, hab. session 1	2.8	3.9	4.0	-2.0	1.9	2.0
Time in familiar zone, hab. session 2	0.1	0.1	0.2	-0.1	0.3	0.4
Time in novel zone, hab. session 2	0.5	0.5	0.8	0.4	-0.6	-0.9
Total zone transitions, hab. session 2	6.8	8.7	9.6	-3.1	3.0	2.7
Total locomotion distance, hab. session 2	7.0	9.1	9.5	-3.0	3.0	3.1
Locomotion velocity, hab. session 2	7.1	9.5	9.7	-3.1	3.0	3.1
Novel to familiar place preference ratio	2.4	2.7	3.0	-1.7	1.7	1.4
Novelty place preference	1.8	1.9	2.3	-1.5	1.5	1.2
Time in novel zone, NPP test	2.2	2.4	2.7	-1.6	1.7	1.3
Total zone transitions, NPP test	4.7	6.8	7.4	-2.7	2.6	2.5
Total locomotion distance, NPP test	8.9	12.1	13.7	-3.3	3.4	3.7
Locomotion velocity, NPP test	7.5	10.6	11.9	-3.1	3.2	3.4
Intraocular pressure	0.4	0.6	1.0	-0.3	1.0	0.7
Delta distance traveled before/after self-admin	2.2	2.4	3.0	-1.5	1.7	1.4
Delta ambulatory time before/after self-admin	2.3	2.8	3.6	-1.7	1.9	1.4
Parametrial fat weight	0.0	0.0	0.0	0.2	0.1	0.2
Pavlov. Cond. lever latency	0.2	0.3	0.5	-0.5	0.7	0.2
Pavlov. Cond. magazine entry latency	2.7	3.5	4.0	1.7	-1.9	-2.0
Pavlov. Cond. change in total contacts	0.3	0.3	0.4	-0.5	0.5	0.6
Pavlov. Cond. index score	1.3	1.6	1.9	1.2	-1.4	-1.2
Pavlov. Cond. latency score	1.7	2.2	2.6	1.5	-1.6	-1.3
Pavlov. Cond. lever contacts	0.1	0.1	0.1	0.3	-0.3	0.1
Pavlov. Cond. magazine entry number	2.9	3.7	3.9	-1.8	2.0	2.0
Pavlov. Cond. intertrial magazine entries	2.2	2.6	2.9	-1.6	1.7	1.5
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.0	1.2	0.9	-1.1	-1.0
Pavlov. Cond. response bias	1.5	1.8	2.1	1.3	-1.4	-1.3
Pavlov. Cond. lever latency	0.8	1.1	1.5	1.2	-1.2	-0.6
Pavlov. Cond. magazine entry latency	0.3	0.3	0.4	-0.3	0.6	0.7
Pavlov. Cond. change in total contacts	0.9	1.4	1.8	-1.1	1.3	1.1
Pavlov. Cond. index score	0.6	0.8	1.1	-0.8	1.0	0.8
Pavlov. Cond. latency score	0.3	0.4	0.6	-0.5	0.8	0.5
Pavlov. Cond. lever contacts	1.3	1.8	2.3	-1.4	1.5	1.0
Pavlov. Cond. magazine entry number	0.4	0.5	0.6	0.5	-0.8	-0.8
Pavlov. Cond. intertrial magazine entries	0.1	0.2	0.3	-0.5	0.4	-0.2
Pavlov. Cond. lever-magazine prob. diff.	0.5	0.7	1.0	-0.8	1.0	0.7
Pavlov. Cond. response bias	1.3	1.8	2.2	-1.2	1.5	1.3
Time in closed arm before self-admin	0.1	0.1	0.1	0.3	-0.3	0.2
Time in closed arm after self-admin	0.7	0.8	1.1	1.0	-0.8	-0.8
Time in open arm before self-admin	0.1	0.1	0.1	-0.2	-0.1	-0.4
Time in open arm after self-admin	0.7	0.8	0.9	-1.0	1.0	0.7
Bone: periosteal estimation	3.3	6.9	7.9	2.8	-2.3	-2.7
Bone: periosteal perimeter	8.2	14.1	14.7	3.8	-3.7	-3.7
Bone: post-yield work	0.2	0.3	0.5	-0.6	0.7	0.4
Progressive ratio test 1 active lever presses	0.2	0.2	0.3	-0.4	0.6	0.5
Progressive ratio test 1 breakpoint	0.2	0.2	0.3	-0.4	0.5	0.5
Progressive ratio test 1 inactive lever presses	0.0	0.0	0.0	0.2	-0.2	-0.2
Progressive ratio test 2 active lever presses	0.5	0.6	0.7	-0.6	0.7	0.9
Progressive ratio test 2 breakpoint	0.4	0.4	0.6	-0.5	0.6	0.8
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.0	0.1	-0.1	0.2
Incentive Sensitization - Responses	0.2	0.3	0.3	0.6	-0.6	-0.3
Incentive Sensitization - Breakpoint	0.3	0.4	0.5	0.7	-0.7	-0.4
Sum of active levers in priming session hrs 5-6	0.0	0.0	0.1	0.2	-0.1	-0.3
Progressive ratio	0.0	0.1	0.2	0.4	0.1	0.2
Food seeking constrained by brief footshock	1.0	1.2	1.6	1.3	-1.2	-0.9
Seeking ratio, punishment vs. effort	0.2	0.3	0.4	0.3	-0.7	-0.7
Retroperitoneal fat weight	0.0	0.0	0.1	0.3	0.1	-0.0
Reaction time number correct	2.3	4.4	5.0	-2.1	2.2	1.9
Reaction time mean minus median	0.2	0.4	0.7	0.7	-0.9	-0.4
Reaction time mean minus median AUC	0.4	1.0	1.4	0.8	-1.2	-0.9
Reaction time num false alarms	0.0	0.0	0.1	0.1	0.1	0.3
Reaction time num false alarms AUC	0.1	0.1	0.2	-0.1	0.4	0.5
Reaction time trials correct on left	2.3	4.4	5.0	-2.1	2.2	1.9
Reaction time trials on left	2.3	4.3	4.9	-2.1	2.2	1.8
Reaction time mean	0.0	0.0	0.0	-0.0	-0.1	-0.1
Reaction time mean AUC	0.0	0.0	0.0	-0.2	0.1	0.2
Median of all reaction times	0.0	0.0	0.0	-0.1	0.0	-0.1
Reaction time omissions	1.1	1.5	2.0	1.4	-1.3	-1.0
Reaction time false alarm rate	0.4	0.5	0.8	0.9	-0.7	-0.5
Reaction time premature initiation rate	3.7	5.1	5.4	-2.3	2.2	2.2
Reaction time premature initiations	5.5	9.8	10.4	-3.2	3.2	3.0
Std. dev. reaction times	0.0	0.0	0.1	0.0	-0.2	0.1
Reaction time trials completed	2.3	4.3	4.9	-2.1	2.2	1.8
Reaction time trials AUC	2.8	5.3	6.0	-2.3	2.5	2.1
Run reversals in cocaine runway, females	0.4	0.4	1.0	1.0	-0.5	-0.2
Run reversals in cocaine runway, males	0.1	0.1	0.2	0.4	-0.1	0.3
Latency to leave start box in cocaine runway	0.3	0.3	0.4	-0.4	0.5	0.7
Latency to leave start box in cocaine runway, F	0.6	0.7	0.8	-0.8	0.8	0.9
Latency to leave start box in cocaine runway, M	0.1	0.1	0.1	-0.1	0.3	0.4
Std. dev. time between licks in bursts	1.8	2.4	3.0	-1.7	1.6	1.3
Total sessions with >9 infusions	0.8	1.0	1.6	1.3	-0.9	-0.8
Short access day 1 total inactive lever presses	1.5	2.0	2.1	1.4	-1.4	-1.4
Short access day 10 total inactive lever presses	0.4	1.0	1.5	0.7	-1.0	-1.2
Short access day 1 total infusions	0.7	1.0	1.2	1.1	-1.0	-0.9
Short access day 10 total infusions	1.1	1.5	2.0	1.4	-1.0	-1.2
Short access total infusions	0.3	0.4	0.6	0.8	-0.5	-0.5
Short access day 1 locomotion	0.3	0.4	0.5	0.7	-0.6	-0.5
Short access day 10 total locomotion	0.4	0.7	1.0	1.0	-0.8	-0.7
Short access total locomotion	1.3	1.5	2.0	1.4	-1.2	-1.0
One hour access (0.3 mA shock)	0.4	0.5	0.7	-0.5	0.7	0.9
Compulsive drug intake	0.4	0.5	0.6	-0.7	0.7	0.8
One hour access (shock baseline)	0.0	0.0	0.1	0.2	-0.0	0.0
Social response proportion	0.3	0.3	0.7	-0.3	0.5	0.8
Social responses	0.1	0.2	0.3	-0.5	0.2	0.5
Social time	0.3	0.4	0.8	-0.4	0.5	0.9
Soleus weight	0.6	1.7	2.8	-1.1	1.0	1.7
Bone: stiffness	1.4	2.3	2.6	1.5	-1.6	-1.5
Tibialis anterior weight	0.2	0.6	0.9	-0.6	0.7	0.9
Time to tail flick, vehicle, before self-admin	0.3	0.3	0.4	-0.7	0.4	0.6
Time to tail flick, vehicle, after self-admin	1.3	1.7	2.4	1.6	-1.4	-0.9
Time to tail flick, test, before self-admin	0.8	0.9	1.2	-1.1	0.9	0.7
Time to tail flick, test, after self-admin	2.3	2.4	2.6	1.6	-1.6	-1.5
Delta time to tail flick, vehicle, before/after SA	0.9	0.9	1.3	1.1	-0.8	-0.8
Delta time to tail flick, test, before/after SA	3.4	3.5	4.0	2.0	-2.0	-1.6
Tibia length	14.4	39.8	42.8	6.5	-6.5	-5.9
Ambulatory time before self-admin	0.8	1.2	1.5	1.2	-1.2	-0.8
Ambulatory time after self-admin	0.6	0.7	1.0	-0.8	1.0	0.7
Bone: tissue strength	0.5	0.5	0.8	-0.9	0.7	0.4
Total heroin consumption	2.8	3.3	4.1	1.8	-1.6	-2.0
Bone: trabecular number	0.2	0.4	0.7	-0.9	0.6	0.1
Bone: trabecular spacing	0.2	0.3	0.6	0.8	-0.4	-0.1
Bone: trabecular thickness	0.3	0.4	0.8	-0.9	0.7	0.2
Bone: trabecular tissue density	0.1	0.2	0.4	0.6	-0.3	0.1
Water consumed over 24 hours	0.3	0.4	0.5	-0.7	0.6	0.6
Number of responses in last shaping day	1.6	1.8	2.1	1.4	-1.4	-1.2