LOC102547955

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 IL isoform ratio XR_594880.3 0.58 0.19 2.8e-03 0.16 0.04 0.13 0.08 9.4e-05 4.4e-02 5.3e-04 5.3e-03
2 PL intron excision ratio chr10_81940032_81952955 0.08 0.06 8.8e-06 0.06 0.05 0.06 0.06 2.9e-07 3.4e-06 6.4e-07 1.1e-06
3 Adipose mRNA stability LOC102547955 0.04 0.03 5.7e-07 0.06 0.06 0.06 0.06 2.0e-07 5.7e-07 4.1e-07 3.0e-07
4 Adipose gene expression LOC102547955 0.03 0.02 1.7e-04 0.03 0.03 0.02 0.03 3.2e-04 4.5e-04 2.7e-03 5.6e-04
5 Liver gene expression LOC102547955 0.02 0.01 9.9e-03 0.02 0.01 0.01 0.02 2.5e-03 1.6e-02 2.6e-02 5.7e-03
6 Brain isoform ratio XR_005490750.1 0.06 0.04 8.7e-07 0.07 0.06 0.04 0.06 9.2e-07 1.8e-06 8.2e-05 2.1e-06
7 pVTA gene expression LOC102547955 0.12 0.11 5.0e-03 0.06 0.03 0.04 0.04 1.1e-03 2.8e-02 1.2e-02 5.2e-03
8 pVTA isoform ratio XR_005490736.1 0.24 0.18 9.4e-03 0.04 0.03 0.03 0.04 5.1e-03 1.4e-02 1.3e-02 7.8e-03
9 Brain intron excision ratio chr10_81940032_81944450 0.15 0.07 0.0e+00 0.22 0.2 0.22 0.22 2.9e-20 1.4e-18 1.0e-19 6.3e-20
10 BLA intron excision ratio chr10_81940032_81944450 0.14 0.08 5.3e-09 0.13 0.15 0.15 0.14 2.4e-07 3.0e-08 2.9e-08 4.7e-08
11 PL isoform ratio XR_005490750.1 0.08 0.04 7.8e-11 0.11 0.1 0.1 0.1 5.7e-12 3.4e-11 3.0e-11 2.6e-11
12 NAcc intron excision ratio chr10_81940032_81952955 0.09 0.06 1.7e-10 0.08 0.09 0.08 0.08 9.4e-10 5.6e-11 9.4e-10 6.8e-10
13 Brain intron excision ratio chr10_81940032_81952955 0.07 0.04 1.6e-08 0.09 0.09 0.08 0.09 1.5e-08 1.0e-08 4.5e-08 1.0e-08
14 Liver mRNA stability LOC102547955 0.03 0.02 1.6e-04 0.02 0.03 0.02 0.02 9.0e-04 5.6e-04 9.3e-04 9.9e-04
15 PL gene expression LOC102547955 0.03 0.02 3.9e-05 0.04 0.04 0.05 0.05 1.8e-05 1.1e-05 6.0e-06 8.3e-06
16 NAcc gene expression LOC102547955 0.02 0.02 1.3e-03 0.02 0.03 0.03 0.03 9.6e-04 3.7e-04 4.5e-04 5.7e-04
17 PL isoform ratio XR_005490736.1 0.09 0.05 6.4e-12 0.09 0.11 0.1 0.1 1.8e-10 1.0e-11 3.9e-11 5.2e-11
18 PL mRNA stability LOC102547955 0.02 0.02 3.0e-03 0.02 0.02 0.01 0.02 4.1e-03 3.2e-03 1.2e-02 3.7e-03
19 NAcc isoform ratio XR_005490750.1 0.04 0.03 1.2e-04 0.03 0.04 0.04 0.03 9.7e-05 3.3e-05 5.1e-05 7.2e-05
20 OFC intron excision ratio chr10_81940032_81944450 0.25 0.15 1.5e-04 0.13 0.14 0.11 0.15 4.6e-04 3.2e-04 1.6e-03 2.6e-04
21 BLA isoform ratio XR_005490750.1 0.06 0.05 9.9e-03 0.04 0.02 0 0.02 1.9e-03 3.1e-02 1.6e-01 2.3e-02
22 Brain isoform ratio XR_005490736.1 0.13 0.07 1.7e-16 0.18 0.18 0.17 0.18 1.8e-16 4.1e-16 7.3e-16 3.3e-16
23 NAcc isoform ratio XR_005490736.1 0.1 0.07 3.3e-09 0.09 0.08 0.07 0.08 1.6e-10 4.3e-09 8.5e-09 1.7e-09
24 BLA isoform ratio XR_005490736.1 0.14 0.12 7.5e-05 0.08 0.07 0.07 0.08 5.1e-05 1.1e-04 1.6e-04 7.0e-05
25 Brain mRNA stability LOC102547955 0.1 0.11 2.1e-04 0.03 0.04 0.04 0.03 1.2e-03 2.7e-04 1.1e-04 1.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
Bone: apparent density1.52.53.9-1.5-1.61.81.71.7-1.7-1.11.11.71.8-1.41.31.4-1.6-1.51.6-1.5-1.81.7-1.6-1.41.51.61.72.0
Area under the delay curve0.40.42.0-0.90.7-0.3-0.3-0.40.51.4-1.4-0.7-0.40.6-0.7-0.60.60.5-0.50.40.4-0.40.50.3-0.2-0.7-0.40.5
BMI with tail11.035.746.61.9-6.86.66.66.5-6.5-3.73.76.46.1-6.36.66.5-6.3-6.26.2-6.4-5.96.0-6.2-6.16.06.36.05.0
BMI without tail1.32.74.90.3-1.51.61.61.6-1.6-0.10.11.71.5-1.91.81.8-1.7-1.81.6-1.9-1.61.7-1.8-1.81.72.11.82.2
Body weight0.73.119.34.4-1.71.61.61.5-1.52.8-2.81.40.6-1.42.31.8-1.2-1.21.0-2.0-0.60.9-1.3-1.41.31.40.71.2
Weight adjusted by age0.80.91.80.51.4-1.1-1.1-1.01.20.6-0.6-0.9-1.20.7-0.9-0.91.00.9-1.00.91.0-1.00.80.9-1.0-0.9-1.2-1.1
Bone surface0.30.61.10.3-0.81.11.01.0-1.00.4-0.40.80.8-0.40.90.8-0.7-0.70.7-0.8-0.70.7-0.8-0.60.70.80.81.0
Bone volume1.11.82.8-0.0-1.41.71.61.6-1.6-0.20.21.51.5-1.21.41.4-1.4-1.41.4-1.5-1.41.4-1.5-1.31.31.41.51.6
Breakpoint value in progressive ratio session4.24.66.01.12.2-2.1-2.1-2.12.11.6-1.6-2.2-2.32.2-2.1-2.22.32.2-2.32.22.4-2.42.12.4-2.4-2.2-1.7-2.3
Number of licking bursts0.10.10.5-0.70.4-0.4-0.4-0.40.4-0.20.2-0.4-0.20.3-0.4-0.40.30.3-0.20.40.2-0.20.40.3-0.4-0.4-0.2-0.1
Context. condit. distance diff. score0.20.20.80.9-0.50.40.40.4-0.4-0.10.10.40.4-0.40.70.6-0.5-0.50.5-0.6-0.40.5-0.4-0.40.40.70.60.5
Locomotion velocity, session 10.40.50.90.9-0.70.70.70.7-0.7-0.30.30.70.6-0.71.00.9-0.8-0.60.7-0.8-0.60.7-0.8-0.60.50.90.60.4
Locomotion distance, session 12.63.44.82.01.9-1.7-1.7-1.71.72.2-2.2-1.6-2.01.8-1.3-1.51.81.9-1.91.52.0-1.91.61.7-1.7-2.0-2.2-2.2
Locomotion velocity, session 21.01.13.51.01.2-1.0-1.0-1.01.01.9-1.9-0.9-1.21.0-0.7-0.91.01.0-1.00.71.1-1.00.81.0-1.0-0.9-1.1-0.6
Locomotion distance, session 23.04.25.91.12.0-1.9-1.9-1.91.92.4-2.4-1.9-2.22.1-1.8-1.92.12.2-2.11.82.2-2.11.92.1-2.0-2.2-2.4-2.1
Locomotion velocity, session 30.10.10.30.20.2-0.0-0.0-0.00.00.6-0.6-0.1-0.20.1-0.1-0.10.20.2-0.20.10.2-0.20.10.1-0.1-0.4-0.4-0.2
Locomotion distance, session 33.23.54.80.82.0-1.8-1.8-1.81.82.2-2.2-2.0-2.01.9-1.7-1.81.92.0-1.91.72.0-1.92.01.9-1.9-1.8-2.1-1.5
Stereotopy head waving bouts, day 34.65.56.5-2.1-2.62.42.42.4-2.4-2.42.42.42.5-2.31.92.1-2.3-2.42.4-2.1-2.52.5-2.3-2.32.32.32.52.5
Stereotopy head waving duration, day 33.23.94.8-1.0-2.22.12.12.1-2.1-1.61.62.12.1-2.11.81.9-2.0-2.02.0-2.0-2.12.1-2.1-1.91.92.02.02.0
Locomotion velocity, session 71.51.62.30.51.3-1.2-1.2-1.21.21.5-1.5-1.2-1.41.2-1.2-1.21.31.3-1.31.21.4-1.31.21.2-1.2-1.5-1.5-1.3
Locomotion distance, session 74.86.17.00.22.6-2.5-2.5-2.52.52.5-2.5-2.6-2.62.6-2.5-2.62.62.6-2.62.42.6-2.52.72.5-2.5-2.6-2.6-2.0
Stereotopy head waving bouts, day 70.70.82.0-0.9-0.70.90.90.9-0.9-1.41.40.90.9-0.90.60.7-0.8-0.90.9-0.7-0.90.8-0.9-0.80.80.91.00.7
Stereotopy head waving duration, day 70.30.41.6-0.3-0.40.60.60.6-0.6-1.31.30.60.6-0.60.40.5-0.6-0.60.6-0.4-0.50.5-0.7-0.60.60.50.70.2
Locomotion velocity, session 80.40.57.92.8-0.50.30.30.3-0.30.7-0.70.3-0.0-0.20.80.6-0.2-0.20.2-0.50.10.0-0.3-0.30.20.30.1-0.5
Locomotion distance, session 80.81.12.61.61.0-1.0-1.0-1.01.01.5-1.5-1.0-1.11.1-0.5-0.71.01.0-1.00.71.1-1.00.90.9-0.9-0.9-1.2-1.1
Degree of sensitization distance0.00.00.10.3-0.1-0.0-0.0-0.00.00.2-0.20.1-0.1-0.0-0.0-0.10.10.0-0.10.00.1-0.1-0.00.1-0.1-0.2-0.1-0.2
Degree of sensitization stereotypy0.20.21.3-1.10.4-0.2-0.2-0.20.2-1.11.1-0.2-0.00.2-0.5-0.30.20.1-0.10.40.1-0.20.20.2-0.2-0.20.1-0.2
Conditioned locomotion1.01.12.1-0.4-1.31.11.11.1-1.1-0.40.41.01.1-1.11.11.1-1.1-1.11.1-1.1-1.21.2-1.0-1.21.21.21.11.5
Cocaine response after cond. corrected5.66.311.4-1.5-2.62.42.42.4-2.5-1.41.42.52.6-2.52.42.5-2.6-2.72.6-2.6-2.82.8-2.6-2.72.72.82.73.4
Cocaine response after cond. not corrected3.33.78.7-1.9-1.91.81.81.8-1.8-0.90.91.91.9-1.81.61.8-1.9-2.02.0-2.0-2.22.1-1.9-2.02.12.12.03.0
Cocaine response before conditioning2.12.63.6-1.01.6-1.6-1.6-1.61.61.0-1.0-1.6-1.61.7-1.9-1.81.71.7-1.71.71.5-1.61.71.7-1.7-1.7-1.7-1.2
Saline control response0.20.30.9-1.00.2-0.3-0.3-0.30.3-0.30.3-0.3-0.30.6-0.7-0.60.50.5-0.50.60.4-0.50.40.5-0.4-0.8-0.5-0.7
Bone: connectivity density0.20.43.4-1.9-0.40.60.50.5-0.5-0.80.80.40.7-0.20.00.2-0.4-0.40.5-0.2-0.60.5-0.3-0.30.30.50.70.9
Bone: cortical apparent density6.18.111.7-2.32.9-3.2-3.2-3.23.20.2-0.2-3.2-2.63.0-3.4-3.22.92.9-2.83.32.6-2.73.13.1-3.1-2.8-2.5-2.5
Bone: cortical area0.10.10.4-0.4-0.00.40.40.4-0.40.5-0.50.40.3-0.10.20.2-0.2-0.10.2-0.3-0.30.3-0.2-0.10.20.10.10.6
Bone: cortical porosity0.50.61.4-1.2-0.50.70.80.8-0.8-0.70.70.70.8-0.70.50.6-0.7-0.70.8-0.7-0.90.8-0.6-0.80.80.70.61.0
Bone: cortical porosity0.40.52.1-1.5-0.50.70.70.7-0.7-0.50.50.60.7-0.70.40.5-0.6-0.60.7-0.6-0.80.8-0.6-0.70.70.60.41.1
Bone: cortical thickness0.30.41.7-1.30.6-0.5-0.6-0.60.60.6-0.6-0.5-0.50.7-0.8-0.70.60.7-0.60.60.4-0.50.60.7-0.7-0.7-0.70.0
Bone: cortical thickness1.21.45.9-2.41.2-1.1-1.1-1.11.11.0-1.0-1.1-1.01.3-1.5-1.41.21.2-1.11.10.8-0.81.21.1-1.1-1.1-1.10.2
Bone: cortical tissue density6.48.512.2-2.33.0-3.3-3.3-3.33.30.3-0.3-3.3-2.73.1-3.5-3.33.03.0-2.93.42.6-2.83.13.2-3.2-2.9-2.5-2.5
Condit. Reinf. active minus inactive responses0.10.10.3-0.60.6-0.3-0.3-0.30.30.1-0.1-0.3-0.20.3-0.4-0.40.30.3-0.30.40.2-0.20.40.4-0.4-0.3-0.10.0
Condit. Reinf. active-inactive response ratio0.30.31.0-1.0-0.20.50.50.5-0.5-0.60.60.60.6-0.60.30.4-0.5-0.50.5-0.4-0.60.5-0.5-0.30.30.50.70.8
Condit. Reinf. active responses0.10.10.6-0.70.4-0.2-0.2-0.20.2-0.20.2-0.3-0.00.3-0.4-0.30.20.2-0.20.40.1-0.20.40.3-0.3-0.2-0.10.0
Condit. Reinf. inactive responses0.30.40.8-0.70.5-0.6-0.6-0.60.6-0.20.2-0.8-0.40.8-0.8-0.70.60.7-0.50.70.5-0.50.90.6-0.5-0.5-0.6-0.4
Incentive salience index mean0.30.31.5-1.20.9-0.6-0.6-0.60.60.0-0.0-0.5-0.40.5-0.8-0.70.50.5-0.50.70.4-0.40.60.7-0.7-0.6-0.4-0.2
Condit. Reinf. lever presses0.91.11.8-1.21.3-1.1-1.1-1.11.1-0.00.0-1.0-0.91.0-1.3-1.21.01.1-1.01.20.9-1.01.11.3-1.3-1.3-1.1-1.0
Condit. Reinf. active minus inactive responses0.20.21.1-1.1-0.30.40.40.4-0.4-0.40.40.40.5-0.40.20.3-0.4-0.30.4-0.3-0.50.5-0.5-0.30.30.30.20.3
Condit. Reinf. active-inactive response ratio0.50.51.2-0.7-0.80.60.60.6-0.6-1.11.10.70.8-0.70.50.6-0.7-0.60.7-0.6-0.80.7-0.7-0.60.70.50.50.3
Condit. Reinf. active responses0.10.11.9-1.40.20.10.10.1-0.1-0.30.3-0.00.2-0.1-0.2-0.1-0.10.00.10.0-0.20.2-0.1-0.0-0.00.1-0.10.1
Condit. Reinf. inactive responses0.30.43.4-1.80.8-0.4-0.4-0.40.4-0.10.1-0.7-0.30.4-0.9-0.70.50.5-0.50.70.3-0.40.50.5-0.6-0.5-0.5-0.3
Condit. Reinf. lever presses0.70.91.3-0.31.1-1.1-1.1-1.11.10.6-0.6-1.1-0.90.9-1.0-1.00.91.0-0.91.00.9-0.90.90.9-1.0-1.0-1.1-1.0
Condit. Reinf. lever reinforcers received0.10.11.8-1.40.4-0.2-0.2-0.20.2-0.20.2-0.30.00.2-0.5-0.30.20.3-0.10.3-0.0-0.10.20.2-0.2-0.2-0.4-0.2
Conditioned reinforcement - actives1.31.32.4-1.5-0.81.00.90.9-0.9-1.21.21.01.2-1.20.81.0-1.2-1.31.3-1.1-1.41.3-1.0-1.21.21.21.21.5
Conditioned reinforcement - inactives0.60.63.5-1.90.8-0.2-0.2-0.30.3-0.30.3-0.5-0.30.7-1.2-1.00.80.8-0.71.00.6-0.70.60.8-0.8-1.0-1.1-0.8
Conditioned locomotion3.94.76.5-1.5-1.72.02.01.9-1.9-1.61.62.32.2-2.42.02.2-2.4-2.42.4-2.3-2.62.5-2.5-2.32.32.22.22.4
Patch foraging indifference point 0 sec1.01.63.4-1.6-0.61.11.11.1-1.2-0.60.61.31.3-1.31.01.1-1.2-1.41.3-1.3-1.51.4-1.4-1.31.31.31.31.9
Patch foraging indifference point AUC0.20.20.80.90.2-0.3-0.3-0.40.3-0.00.0-0.5-0.30.2-0.3-0.30.40.3-0.40.50.5-0.50.40.3-0.4-0.6-0.2-0.9
Delay disc. indifference point, 0s delay0.91.01.8-1.20.9-0.9-0.9-0.80.90.2-0.2-1.1-0.91.1-1.3-1.21.11.0-1.11.21.0-1.01.10.9-0.9-1.1-0.7-0.8
Delay disc. indifference point, 16s delay0.40.41.8-0.5-0.50.60.60.6-0.60.9-0.90.40.6-0.50.50.5-0.5-0.50.6-0.7-0.60.7-0.5-0.60.80.40.41.3
Delay disc. indifference point, 2s delay0.40.43.1-1.80.6-0.2-0.2-0.20.41.0-1.0-0.4-0.50.4-0.8-0.70.60.6-0.50.50.4-0.40.40.4-0.4-0.8-0.60.3
Delay disc. indifference point, 24s delay0.50.52.30.31.2-0.6-0.6-0.60.71.5-1.5-0.7-0.70.7-0.5-0.60.60.6-0.60.50.6-0.50.70.5-0.3-0.5-0.60.2
Delay disc. indifference point, 4s delay3.43.67.2-0.62.0-1.7-1.7-1.71.82.7-2.7-2.0-1.92.0-2.1-2.12.11.8-2.01.81.9-1.91.91.8-1.8-1.9-1.6-0.6
Delay disc. indifference point, 8s delay0.20.21.2-1.10.5-0.3-0.3-0.30.30.7-0.7-0.5-0.20.4-0.5-0.40.30.2-0.30.30.1-0.20.40.1-0.0-0.2-0.00.6
Indifference point function ln k0.00.10.4-0.30.5-0.2-0.2-0.20.20.4-0.4-0.1-0.10.20.10.1-0.1-0.00.1-0.2-0.20.20.1-0.20.20.3-0.10.6
Indifference point function log k0.00.10.4-0.30.5-0.2-0.2-0.20.20.4-0.4-0.1-0.10.20.10.1-0.1-0.00.1-0.2-0.20.20.1-0.20.20.3-0.10.6
Patch foraging total patch changes 0 sec0.91.53.2-1.3-0.61.11.21.2-1.2-0.40.41.31.2-1.31.11.1-1.2-1.31.3-1.3-1.41.4-1.4-1.31.31.21.31.8
Patch foraging total patch changes 12 sec0.50.65.7-2.4-0.30.30.40.4-0.4-0.90.90.30.7-0.60.10.3-0.5-0.70.6-0.4-0.80.7-0.4-0.70.80.50.81.2
Patch foraging total patch changes 18 sec1.41.82.3-0.3-1.41.41.41.4-1.5-1.41.41.31.5-1.51.31.4-1.4-1.41.4-1.3-1.41.4-1.4-1.51.51.11.20.8
Patch foraging total patch changes 24 sec1.72.12.9-1.1-1.21.61.61.6-1.7-1.11.11.61.5-1.61.21.2-1.4-1.61.4-1.3-1.51.5-1.7-1.41.41.31.71.6
Patch foraging total patch changes 6 sec0.81.31.8-1.1-0.80.91.01.0-1.0-1.01.00.91.3-1.31.01.1-1.2-1.21.2-1.1-1.31.3-1.1-1.31.31.11.11.3
Patch foraging time to switch 0 sec0.10.10.3-0.5-0.30.20.20.3-0.3-0.50.50.40.4-0.30.30.3-0.4-0.40.4-0.3-0.40.4-0.3-0.30.40.40.40.4
Patch foraging water rate 0 sec0.61.01.60.6-1.11.21.11.1-1.10.5-0.51.10.9-0.91.11.0-0.9-1.10.9-1.2-0.91.0-1.1-1.11.01.00.91.3
Patch foraging water rate 12 sec0.20.31.60.80.4-0.2-0.2-0.30.41.3-1.3-0.4-0.50.4-0.2-0.30.40.5-0.40.20.5-0.40.40.4-0.4-0.4-0.6-0.1
Patch foraging water rate 18 sec0.50.71.5-0.80.8-0.6-0.6-0.60.71.2-1.2-0.6-0.80.8-1.0-1.00.90.8-0.90.80.8-0.80.70.9-1.1-1.0-0.9-0.1
Patch foraging water rate 24 sec0.50.71.9-0.6-0.91.00.90.9-0.9-0.00.01.00.8-0.70.70.8-0.9-0.90.9-0.9-0.90.9-0.9-1.00.90.80.71.4
Patch foraging water rate 6 sec0.00.10.3-0.60.10.20.10.10.0-0.20.2-0.0-0.10.3-0.4-0.40.30.2-0.20.30.2-0.20.10.2-0.3-0.5-0.3-0.3
Seeking ratio, delayed vs. immediate footshock0.30.31.10.2-0.70.60.60.6-0.5-0.80.80.50.6-0.30.60.6-0.6-0.40.6-0.5-0.60.6-0.4-0.60.61.00.20.5
Distance traveled before self-admin0.50.51.3-0.30.6-0.6-0.6-0.70.70.8-0.8-0.6-0.70.7-0.8-0.80.80.6-0.80.70.7-0.70.60.7-0.8-1.1-0.4-0.7
Distance traveled after self-admin1.21.32.51.2-1.01.01.00.9-0.9-0.40.40.90.9-1.31.51.4-1.2-1.51.2-1.4-1.11.2-0.9-1.41.31.31.61.1
Extensor digitorum longus weight0.51.929.65.4-0.30.50.50.5-0.52.3-2.30.4-0.2-0.61.71.2-0.5-0.30.3-1.00.20.0-0.5-0.60.60.4-0.2-0.6
Bone: elastic displacement0.10.20.4-0.4-0.40.40.30.3-0.3-0.20.20.50.4-0.60.40.4-0.4-0.40.4-0.5-0.50.5-0.5-0.30.30.50.30.5
Bone: elastic work0.10.10.6-0.10.00.0-0.0-0.00.00.8-0.8-0.0-0.0-0.10.20.2-0.10.00.1-0.3-0.10.2-0.0-0.10.10.2-0.20.6
Bone: endosteal estimation0.41.03.82.0-0.51.01.01.0-1.01.0-1.00.90.6-0.81.31.1-0.8-0.90.8-1.1-0.60.7-0.8-0.90.91.00.81.0
Bone: endosteal perimeter0.61.22.91.7-0.71.31.31.3-1.30.5-0.51.20.9-1.01.41.2-1.0-1.00.9-1.2-0.80.9-1.0-1.01.01.01.10.9
Epididymis fat weight0.10.11.00.8-0.10.10.10.1-0.11.0-1.0-0.1-0.2-0.10.20.2-0.00.10.0-0.20.00.00.20.0-0.10.1-0.40.2
Delta time in closed arm before/after self-admin0.30.33.82.00.5-0.4-0.4-0.30.40.6-0.6-0.5-0.40.30.20.10.10.0-0.20.00.3-0.30.40.1-0.20.30.6-0.1
Delta time in open arm before/after self-admin0.20.20.7-0.50.3-0.4-0.4-0.40.2-0.30.3-0.4-0.20.2-0.6-0.50.40.5-0.40.60.4-0.50.40.4-0.5-0.7-0.7-0.9
Diff in mean of infusions in LGA sessions0.50.51.40.10.7-0.6-0.6-0.60.5-0.10.1-1.0-0.71.1-0.9-0.90.80.7-0.81.00.8-0.91.00.9-1.2-0.4-0.1-0.5
Delay discount exponential model param0.50.53.00.6-0.90.40.40.5-0.6-1.71.70.70.6-0.60.70.7-0.6-0.50.6-0.5-0.50.5-0.6-0.40.20.70.4-0.5
Extinction: sum of active levers before priming1.01.02.11.11.5-1.2-1.2-1.31.30.7-0.7-1.1-1.21.0-0.8-0.91.00.9-1.00.91.0-1.01.00.8-0.8-0.9-0.6-1.0
Active lever presses in extinction session 60.20.10.4-0.2-0.30.60.60.4-0.4-0.50.50.40.4-0.10.30.3-0.4-0.30.4-0.4-0.40.4-0.4-0.20.20.20.60.2
Bone: final force0.30.41.9-1.4-0.40.70.70.7-0.7-0.10.10.60.7-0.40.40.5-0.6-0.50.6-0.6-0.80.7-0.5-0.60.60.50.41.2
Bone: final moment0.30.51.7-1.3-0.50.80.80.8-0.80.0-0.00.70.7-0.50.50.6-0.7-0.60.7-0.7-0.80.8-0.6-0.70.70.50.51.3
Food consumed during 24 hour testing period1.41.72.31.11.5-1.4-1.4-1.41.41.0-1.0-1.3-1.41.3-1.0-1.21.31.3-1.31.21.4-1.41.31.3-1.3-1.2-1.2-1.4
Glucose0.50.81.8-1.0-1.30.90.90.9-0.90.3-0.30.70.8-0.80.70.8-0.8-0.80.8-1.0-0.91.0-0.7-1.01.00.90.51.3
Heart weight1.31.93.51.8-1.91.71.71.8-1.8-0.00.01.61.3-1.31.71.5-1.3-1.31.2-1.5-1.01.1-1.5-1.21.21.01.10.6
Delay discount hyperbolic model param0.80.83.30.9-1.00.60.60.7-0.8-1.81.80.90.8-0.80.90.9-0.9-0.70.8-0.7-0.70.7-0.8-0.60.50.90.6-0.3
Intermittent access intake day 1-15 change2.32.34.0-0.3-1.72.02.02.0-1.6-0.80.81.81.6-1.81.41.5-1.5-1.51.5-1.6-1.51.5-1.5-1.51.51.21.11.2
Intermittent access intake escalation2.42.43.7-0.4-1.71.91.91.9-1.7-1.01.01.81.7-1.81.51.6-1.6-1.61.6-1.6-1.61.6-1.5-1.51.51.21.31.1
Intermittent access intake escalation 21.81.73.10.5-1.71.71.71.8-1.5-0.70.71.41.4-1.41.41.4-1.4-1.31.3-1.4-1.21.3-1.3-1.31.31.00.90.7
Intermitt. access day 1 inactive lever presses0.30.41.5-1.20.0-0.3-0.3-0.10.0-0.40.4-0.5-0.10.8-0.9-0.70.60.8-0.50.80.5-0.50.60.7-0.7-0.7-0.9-0.6
Intermitt. access day 15 inactive lever presses0.60.72.9-1.7-1.10.80.80.8-0.8-1.61.60.61.1-0.30.10.3-0.6-0.50.6-0.2-0.70.6-0.6-0.40.40.40.50.4
Intermitt. access escalation Index2.42.14.70.8-0.71.11.11.1-1.0-0.10.11.41.2-1.41.71.6-1.5-1.81.5-1.7-1.41.5-1.4-1.81.82.02.22.0
Intermittent access day 1 total infusions0.30.41.1-0.20.9-1.0-1.0-1.00.8-0.00.0-0.8-0.60.6-0.6-0.50.50.4-0.50.60.4-0.40.80.3-0.3-0.3-0.1-0.2
Intermittent access day 15 total infusions0.20.30.5-0.5-0.30.40.30.4-0.3-0.60.60.40.5-0.60.40.5-0.5-0.70.5-0.5-0.60.6-0.3-0.60.60.40.70.5
Intermittent access terminal intake (last 3 days)0.20.20.7-0.4-0.40.40.40.4-0.4-0.80.80.40.6-0.40.30.4-0.5-0.60.5-0.4-0.50.5-0.3-0.50.50.40.60.3
Intermittent access total infusions0.00.00.2-0.20.1-0.1-0.1-0.20.1-0.00.0-0.00.1-0.10.00.1-0.1-0.30.1-0.1-0.20.20.0-0.20.20.10.40.4
Intermittent access day 1 locomotion0.20.20.6-0.60.7-0.7-0.8-0.80.60.1-0.1-0.4-0.40.5-0.6-0.50.40.3-0.40.50.3-0.30.40.3-0.4-0.4-0.2-0.1
Intermittent access day 15 total locomotion0.40.40.7-0.5-0.50.60.60.6-0.7-0.80.80.80.7-0.60.40.5-0.6-0.60.6-0.5-0.70.7-0.6-0.60.60.50.60.5
Intermittent access total locomotion0.60.71.1-0.9-0.50.70.60.7-0.7-0.70.71.00.9-0.80.70.8-0.9-0.90.9-0.8-1.01.0-0.9-0.90.90.80.91.0
Intermittent access standard deviation2.02.24.2-0.5-1.92.02.01.9-1.9-0.90.91.71.7-1.51.31.3-1.4-1.41.4-1.4-1.41.4-1.6-1.41.41.01.41.0
Left kidney weight0.41.210.22.70.1-0.1-0.1-0.1-0.03.2-3.2-0.1-0.70.30.50.10.30.3-0.4-0.30.6-0.40.20.2-0.1-0.2-0.60.2
Right kidney weight0.41.13.21.3-0.91.11.01.0-1.01.8-1.80.80.5-0.91.31.1-0.8-0.70.8-1.3-0.70.8-0.9-0.90.90.90.41.3
Cocaine induced anxiety0.20.23.11.8-0.40.30.30.3-0.30.4-0.40.30.1-0.10.50.4-0.2-0.20.2-0.30.00.0-0.4-0.30.30.00.3-0.3
Post-drug Anxiety0.50.62.00.10.5-0.7-0.6-0.60.6-0.40.4-0.8-0.60.9-0.8-0.70.70.8-0.70.90.8-0.80.70.8-0.8-0.9-0.6-1.4
Baseline Anxiety0.40.45.4-2.3-0.1-0.10.0-0.0-0.0-1.41.4-0.20.20.2-0.6-0.40.10.2-0.00.5-0.1-0.00.30.3-0.3-0.2-0.3-0.3
Tail length10.331.249.11.66.4-5.9-5.9-5.95.97.0-7.0-5.7-6.25.4-5.1-5.55.85.5-5.85.05.8-5.65.55.3-5.4-5.1-5.6-3.4
Length with tail7.426.958.84.05.3-5.0-5.0-5.05.07.7-7.7-5.1-5.75.0-3.9-4.55.25.1-5.34.25.5-5.25.04.7-4.7-4.8-5.5-3.8
Length without tail0.71.59.63.10.5-0.5-0.5-0.50.52.4-2.4-0.9-1.11.0-0.1-0.40.81.0-0.90.41.1-1.01.00.7-0.7-1.0-1.4-1.2
Times rat made contact with spout0.10.10.8-0.90.5-0.4-0.4-0.40.4-0.30.3-0.2-0.10.2-0.4-0.30.20.2-0.20.30.1-0.10.10.3-0.3-0.20.0-0.0
Lifetime Intake0.00.00.1-0.10.4-0.3-0.3-0.40.3-0.00.0-0.2-0.10.1-0.1-0.10.1-0.1-0.00.1-0.0-0.00.2-0.10.00.00.30.2
Liver weight, left0.81.31.90.41.0-0.9-0.9-1.01.01.4-1.4-1.1-1.11.3-1.1-1.11.21.3-1.21.11.2-1.21.21.3-1.3-1.2-1.2-0.9
Liver weight, right1.22.06.00.10.9-0.9-1.0-1.11.12.5-2.5-1.3-1.41.6-1.3-1.41.51.5-1.51.21.4-1.31.61.3-1.3-1.3-1.6-0.4
Locomotor activity0.71.12.6-0.9-0.71.00.90.9-0.9-1.61.61.11.1-0.90.80.9-1.0-1.21.1-0.8-1.11.1-1.0-1.11.01.21.31.0
Locomotor testing distance1.52.47.5-2.3-1.01.31.21.3-1.2-2.72.71.41.6-1.30.81.1-1.4-1.51.5-1.0-1.71.5-1.4-1.41.41.41.71.3
Locomotor testing rearing0.40.75.9-2.4-0.30.40.30.4-0.4-2.12.10.40.6-0.1-0.4-0.1-0.2-0.30.30.2-0.50.4-0.3-0.10.20.10.60.1
Locomotion in novel chamber0.70.91.8-1.30.8-1.0-1.0-1.00.90.5-0.5-1.1-0.81.1-1.3-1.11.01.0-0.91.10.7-0.81.11.1-1.1-0.9-0.4-0.0
Locomotion in novel chamber post-restriction1.51.93.1-0.8-1.01.31.31.2-1.2-1.81.81.21.5-1.71.21.4-1.5-1.51.5-1.3-1.51.5-1.3-1.31.21.21.60.8
Fecal boli incidents, locomotor time 12.62.95.50.7-2.42.02.02.0-1.9-1.11.11.71.9-1.71.91.8-1.7-1.61.7-1.7-1.61.6-1.8-1.61.81.61.41.0
Change in fecal boli incidents, locomotor task2.42.23.8-0.31.9-1.8-1.8-1.81.81.0-1.0-1.6-1.71.4-1.6-1.61.61.3-1.51.51.5-1.51.61.3-1.5-1.6-1.3-1.0
Time >=10cm from walls, locomotor time 10.40.42.0-1.10.7-0.6-0.6-0.60.6-1.41.4-0.5-0.20.5-0.6-0.50.40.2-0.30.60.2-0.30.50.2-0.3-0.3-0.1-0.3
Bouts of movement, locomotor time 10.10.10.60.3-0.40.20.20.2-0.10.8-0.80.20.2-0.20.40.2-0.20.00.2-0.3-0.20.2-0.2-0.10.30.3-0.50.4
Total resting periods, locomotor time 10.20.21.10.4-0.60.40.40.4-0.31.0-1.00.30.4-0.30.50.4-0.3-0.10.3-0.5-0.30.3-0.3-0.20.50.4-0.50.6
Rest time, locomotor task time 10.30.30.9-0.5-0.70.60.60.6-0.50.7-0.70.40.6-0.60.40.4-0.4-0.30.4-0.5-0.50.5-0.4-0.50.50.4-0.10.9
Distance moved, locomotor task time 10.91.01.6-0.21.2-1.3-1.3-1.31.20.4-0.4-0.9-1.11.2-1.1-1.11.10.8-1.01.11.0-1.01.01.0-1.0-0.8-0.2-0.6
Vertical activity count, locomotor time 10.30.30.80.30.9-0.9-0.9-0.90.8-0.40.4-0.4-0.70.6-0.4-0.50.50.1-0.50.50.4-0.50.50.3-0.4-0.10.1-0.5
Time >=10cm from walls, locomotor time 20.70.72.4-1.51.0-0.9-0.9-0.90.9-0.40.4-0.8-0.70.8-1.1-0.90.80.8-0.70.90.6-0.60.80.8-0.9-0.6-1.0-0.5
Bouts of movement, locomotor time 20.10.10.4-0.5-0.40.40.40.4-0.4-0.60.60.30.4-0.30.20.3-0.3-0.20.4-0.3-0.40.4-0.3-0.10.40.30.10.2
Total resting periods, locomotor time 20.10.10.5-0.4-0.40.40.40.4-0.4-0.70.70.30.4-0.30.30.3-0.4-0.20.4-0.3-0.40.4-0.3-0.20.40.30.10.1
Rest time, locomotor task time 21.01.22.00.71.0-1.1-1.1-1.21.20.3-0.3-1.3-1.01.2-1.0-1.11.11.2-1.11.21.2-1.21.21.1-1.1-1.1-1.0-1.4
Distance moved, locomotor task time 20.20.32.10.20.5-0.5-0.5-0.50.41.4-1.4-0.1-0.50.3-0.2-0.20.30.2-0.30.00.3-0.20.10.2-0.2-0.2-0.10.4
Vertical activity count, locomotor time 20.20.31.50.00.3-0.1-0.1-0.10.11.1-1.10.4-0.1-0.40.40.3-0.2-0.50.2-0.6-0.30.4-0.4-0.40.40.60.51.2
Light reinforcement 10.61.14.7-2.2-0.90.60.70.7-0.8-2.02.00.71.1-0.80.40.6-0.9-0.91.0-0.5-1.11.0-0.9-0.70.70.80.90.7
Light reinforcement 20.10.11.0-1.0-0.10.20.10.1-0.1-0.40.40.10.3-0.40.00.1-0.2-0.30.3-0.2-0.40.3-0.2-0.30.20.40.50.7
Bone: marrow area0.30.73.61.9-0.30.90.90.9-0.91.0-1.00.70.5-0.61.10.9-0.7-0.70.6-1.0-0.50.6-0.7-0.80.80.80.70.8
Bone: maximum diameter0.50.91.5-0.1-0.51.21.21.2-1.20.0-0.01.01.0-0.80.90.9-0.9-0.90.9-1.0-0.90.9-0.9-0.90.90.90.91.2
Bone: maximum force0.50.92.4-0.3-0.81.11.11.1-1.10.4-0.40.90.9-0.71.01.0-1.0-0.91.0-1.1-1.01.1-0.9-1.01.01.00.71.6
Bone: maximum moment0.61.02.8-0.3-0.91.11.11.1-1.10.6-0.61.01.0-0.81.11.1-1.0-0.91.0-1.2-1.11.1-0.9-1.01.01.00.71.7
Mean time between licks in bursts0.10.11.21.1-0.20.20.20.2-0.2-0.00.00.30.2-0.40.60.5-0.3-0.30.3-0.4-0.20.2-0.3-0.40.40.30.2-0.2
Mean num. licks in bursts0.00.00.1-0.20.2-0.2-0.2-0.20.20.1-0.1-0.1-0.20.2-0.2-0.20.20.2-0.20.20.2-0.20.10.3-0.2-0.2-0.2-0.1
Cd content in liver0.60.71.0-0.40.8-0.8-0.8-0.80.8-0.10.1-0.9-0.70.8-1.0-1.00.90.9-0.91.00.8-0.80.91.0-1.0-0.8-0.7-0.9
Co content in liver0.10.11.71.3-0.50.10.20.2-0.20.3-0.30.1-0.0-0.10.40.2-0.1-0.10.1-0.20.1-0.0-0.1-0.10.00.10.2-0.2
Cu content in liver1.82.23.91.12.0-1.5-1.4-1.41.41.0-1.0-1.7-1.41.5-1.3-1.41.51.5-1.51.51.6-1.61.81.5-1.5-1.4-1.4-1.6
Fe content in liver1.51.83.81.31.1-1.1-1.1-1.11.11.9-1.9-1.3-1.41.4-1.0-1.21.31.4-1.41.11.5-1.41.31.3-1.3-1.3-1.5-1.1
K content in liver0.20.20.3-0.3-0.40.50.60.6-0.6-0.20.20.40.4-0.40.30.3-0.4-0.40.4-0.4-0.40.4-0.3-0.30.40.40.40.6
Mg content in liver0.60.61.2-0.41.1-0.7-0.6-0.60.60.2-0.2-0.9-0.70.9-1.0-0.90.80.9-0.80.90.8-0.81.00.9-0.9-0.9-0.8-0.8
Mn content in liver2.12.43.4-0.51.8-1.6-1.7-1.71.7-0.00.0-1.7-1.51.5-1.8-1.71.61.6-1.61.81.5-1.61.51.8-1.7-1.7-1.3-1.8
Na content in liver0.91.01.6-0.5-0.81.01.11.1-1.1-1.31.31.31.1-0.90.90.9-1.0-1.01.0-0.9-1.01.0-1.1-0.90.90.81.10.7
Rb content in liver0.20.21.9-1.4-0.0-0.00.00.0-0.0-0.80.8-0.60.10.4-0.6-0.40.20.5-0.20.50.1-0.20.50.3-0.3-0.4-0.6-0.4
Se content in liver0.30.31.9-1.4-0.80.70.70.7-0.7-0.60.60.60.7-0.40.10.2-0.4-0.40.4-0.3-0.50.5-0.4-0.30.40.40.50.7
Sr content in liver1.81.72.60.51.6-1.6-1.6-1.61.51.4-1.4-1.1-1.61.0-1.2-1.31.41.2-1.41.21.3-1.31.11.3-1.3-1.3-1.1-1.0
Zn content in liver0.20.22.8-1.70.00.20.20.2-0.2-1.01.00.30.3-0.3-0.2-0.0-0.2-0.10.20.0-0.30.2-0.20.0-0.0-0.10.10.1
Bone: minimum diameter0.10.21.30.9-0.10.40.40.4-0.41.1-1.10.30.1-0.20.50.4-0.2-0.20.2-0.5-0.10.2-0.3-0.30.30.20.10.5
Time in familiar zone, hab. session 10.60.50.9-0.90.5-0.8-0.8-0.80.8-0.80.8-0.9-0.50.8-0.9-0.80.70.7-0.60.90.6-0.60.90.8-0.8-0.5-0.4-0.7
Time in novel zone, hab. session 12.92.83.5-0.7-1.71.81.81.8-1.8-1.11.11.91.7-1.91.61.7-1.7-1.81.8-1.8-1.81.8-1.9-1.81.81.61.61.7
Total zone transitions, hab. session 16.28.710.41.62.9-3.0-3.0-3.03.02.4-2.4-3.0-3.23.1-2.7-2.83.03.2-3.12.93.2-3.23.03.0-3.0-3.1-3.2-3.2
Total locomotion distance, hab. session 12.43.54.3-0.11.9-1.9-1.9-1.91.91.2-1.2-2.0-1.92.0-2.0-2.01.92.1-1.92.01.9-1.92.02.0-2.0-1.9-2.1-1.9
Locomotion velocity, hab. session 13.44.86.10.72.2-2.2-2.2-2.22.21.9-1.9-2.2-2.32.3-2.1-2.22.32.4-2.32.22.3-2.32.22.3-2.3-2.2-2.5-2.2
Time in familiar zone, hab. session 20.40.51.7-1.0-1.00.60.60.6-0.6-1.31.30.50.7-0.60.40.5-0.6-0.50.6-0.4-0.70.6-0.5-0.40.40.50.60.3
Time in novel zone, hab. session 20.10.10.4-0.00.4-0.2-0.2-0.20.20.7-0.7-0.2-0.30.2-0.2-0.20.20.2-0.20.10.2-0.20.20.1-0.0-0.2-0.20.2
Total zone transitions, hab. session 21.72.12.80.71.7-1.5-1.5-1.51.50.9-0.9-1.5-1.51.5-1.3-1.41.51.6-1.51.51.6-1.61.51.6-1.5-1.5-1.5-1.7
Total locomotion distance, hab. session 20.00.00.10.10.1-0.0-0.0-0.00.00.0-0.0-0.1-0.10.1-0.1-0.10.10.2-0.10.10.1-0.10.10.2-0.2-0.1-0.3-0.3
Locomotion velocity, hab. session 20.00.10.20.30.3-0.1-0.1-0.10.10.5-0.5-0.2-0.20.2-0.1-0.10.20.3-0.20.10.2-0.20.20.3-0.3-0.1-0.4-0.2
Novel to familiar place preference ratio1.01.12.61.60.8-1.0-1.0-1.01.01.5-1.5-1.0-1.21.0-0.6-0.81.00.9-1.00.81.1-1.01.00.8-0.8-0.8-0.8-0.8
Novelty place preference1.11.22.31.30.8-1.1-1.1-1.11.11.5-1.5-1.1-1.21.2-0.8-0.91.10.9-1.10.91.1-1.11.10.9-0.9-0.9-0.9-0.7
Time in novel zone, NPP test0.80.81.40.80.7-1.0-1.0-1.01.01.2-1.2-1.0-1.01.0-0.8-0.91.00.8-1.00.81.0-0.91.00.8-0.8-0.8-0.7-0.6
Total zone transitions, NPP test3.34.76.80.52.4-2.2-2.2-2.22.21.6-1.6-2.1-2.32.3-2.1-2.22.22.4-2.22.22.3-2.32.02.3-2.3-2.4-2.6-2.5
Total locomotion distance, NPP test0.81.12.2-0.21.1-0.9-0.9-0.91.00.6-0.6-1.0-1.01.0-1.1-1.11.01.2-1.11.11.1-1.10.91.1-1.1-1.3-1.5-1.3
Locomotion velocity, NPP test1.31.83.40.41.4-1.2-1.2-1.21.21.3-1.3-1.3-1.41.4-1.3-1.31.41.6-1.41.31.4-1.41.21.4-1.4-1.6-1.8-1.6
Intraocular pressure1.31.72.81.51.4-1.4-1.4-1.41.41.7-1.7-1.6-1.41.4-0.9-1.11.31.2-1.31.11.4-1.31.41.3-1.2-0.8-1.0-0.7
Delta distance traveled before/after self-admin2.42.54.31.4-1.31.31.31.3-1.3-1.31.31.31.4-1.72.01.9-1.8-1.81.7-1.8-1.71.7-1.3-1.91.92.11.71.3
Delta ambulatory time before/after self-admin2.52.74.20.8-1.41.51.51.5-1.5-1.21.21.51.5-1.92.01.9-1.9-1.81.8-1.9-1.81.8-1.4-1.91.92.01.51.5
Parametrial fat weight0.10.22.2-1.50.30.10.10.1-0.2-0.20.20.20.3-0.1-0.00.1-0.2-0.30.3-0.2-0.50.4-0.0-0.20.20.50.51.1
Pavlov. Cond. lever latency1.41.84.22.0-1.71.31.31.3-1.30.1-0.11.11.1-1.21.81.6-1.3-1.41.3-1.5-1.11.2-1.2-1.51.51.61.31.2
Pavlov. Cond. magazine entry latency0.50.711.9-3.50.5-0.1-0.1-0.10.1-1.31.3-0.00.30.0-0.7-0.4-0.0-0.10.10.3-0.50.30.10.1-0.10.00.30.7
Pavlov. Cond. change in total contacts2.12.36.3-2.51.8-1.6-1.6-1.61.6-0.40.4-1.5-1.11.6-2.0-1.81.41.4-1.31.81.1-1.21.61.6-1.6-1.4-1.1-0.9
Pavlov. Cond. index score0.81.010.4-3.21.2-0.8-0.8-0.80.8-0.90.9-0.6-0.40.7-1.4-1.10.70.7-0.61.00.3-0.50.70.8-0.8-0.8-0.5-0.3
Pavlov. Cond. latency score0.81.08.1-2.81.2-0.9-0.9-0.90.9-0.70.7-0.7-0.50.8-1.4-1.10.80.8-0.71.10.4-0.60.80.9-0.9-1.0-0.7-0.5
Pavlov. Cond. lever contacts1.82.23.6-1.81.9-1.5-1.5-1.51.50.0-0.0-1.3-1.31.4-1.9-1.71.41.5-1.41.71.2-1.41.41.6-1.6-1.7-1.4-1.4
Pavlov. Cond. magazine entry number0.81.014.03.7-0.90.50.50.5-0.51.7-1.70.3-0.0-0.41.20.8-0.3-0.40.2-0.80.10.1-0.4-0.50.50.40.0-0.1
Pavlov. Cond. intertrial magazine entries0.60.71.91.40.4-0.7-0.7-0.70.71.0-1.0-1.0-0.80.9-0.5-0.70.80.9-0.80.70.9-0.91.00.7-0.7-0.7-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.0.81.011.4-3.41.2-0.8-0.8-0.80.8-1.01.0-0.6-0.30.6-1.4-1.00.60.6-0.51.00.2-0.40.60.8-0.8-0.7-0.4-0.1
Pavlov. Cond. response bias0.91.111.3-3.41.2-0.8-0.8-0.80.8-1.11.1-0.7-0.40.8-1.4-1.10.70.7-0.61.10.3-0.40.80.8-0.8-0.8-0.5-0.3
Pavlov. Cond. lever latency0.60.71.30.41.1-0.9-0.9-0.90.90.8-0.8-0.8-0.90.9-0.8-0.80.90.9-0.90.80.9-0.91.00.9-0.8-0.8-0.7-0.6
Pavlov. Cond. magazine entry latency0.50.61.00.20.5-0.9-0.9-0.90.91.0-1.0-0.7-0.90.6-0.7-0.70.80.7-0.80.60.7-0.70.60.8-0.8-0.7-0.8-0.5
Pavlov. Cond. change in total contacts0.20.30.8-0.9-0.40.40.40.4-0.5-0.50.50.40.6-0.60.30.5-0.6-0.60.6-0.5-0.60.6-0.6-0.70.60.40.40.4
Pavlov. Cond. index score0.20.30.5-0.4-0.60.40.40.4-0.5-0.10.10.50.5-0.60.50.5-0.6-0.60.6-0.6-0.60.6-0.7-0.60.60.60.40.7
Pavlov. Cond. latency score0.10.10.3-0.2-0.40.20.20.2-0.30.3-0.30.30.3-0.40.30.3-0.3-0.40.4-0.4-0.40.4-0.5-0.40.40.40.20.6
Pavlov. Cond. lever contacts0.50.71.0-1.0-1.00.80.80.8-0.8-0.90.90.80.9-0.80.60.7-0.8-0.80.9-0.7-0.90.9-0.9-0.80.80.80.70.6
Pavlov. Cond. magazine entry number0.00.10.40.40.10.20.20.2-0.1-0.60.60.10.10.1-0.0-0.00.00.0-0.00.10.1-0.10.10.1-0.0-0.10.1-0.5
Pavlov. Cond. intertrial magazine entries1.82.35.01.21.4-1.3-1.3-1.31.40.8-0.8-1.6-1.51.7-1.4-1.41.51.7-1.61.61.7-1.71.71.6-1.5-1.7-1.7-2.2
Pavlov. Cond. lever-magazine prob. diff.0.30.40.6-0.3-0.70.50.50.5-0.5-0.00.00.60.5-0.70.60.6-0.6-0.70.6-0.7-0.70.7-0.8-0.70.60.60.40.7
Pavlov. Cond. response bias0.50.61.2-1.1-0.90.70.70.7-0.7-0.70.70.70.8-0.90.60.7-0.8-0.80.8-0.7-0.90.9-0.9-0.80.80.80.60.8
Time in closed arm before self-admin1.01.12.4-1.5-1.61.41.41.4-1.5-0.70.71.31.2-1.20.70.8-1.0-0.81.0-0.9-1.01.0-1.3-0.90.80.30.30.6
Time in closed arm after self-admin0.50.51.00.8-1.00.90.90.9-0.90.3-0.30.60.6-0.70.80.8-0.7-0.70.6-0.7-0.50.6-0.7-0.60.60.70.80.6
Time in open arm before self-admin0.40.43.51.91.2-0.9-0.9-1.01.0-0.00.0-0.6-0.80.60.1-0.10.30.2-0.30.20.4-0.40.70.1-0.10.10.1-0.6
Time in open arm after self-admin0.60.61.80.31.2-1.0-1.0-1.01.0-0.70.7-0.8-0.70.6-0.6-0.60.60.7-0.60.80.7-0.70.90.5-0.6-0.6-0.7-1.3
Bone: periosteal estimation0.40.81.50.6-0.51.21.11.1-1.10.6-0.61.00.8-0.81.11.0-0.9-0.80.8-1.1-0.80.9-0.8-0.90.90.90.81.2
Bone: periosteal perimeter0.40.71.10.9-0.71.11.01.0-1.00.5-0.51.00.7-0.71.00.8-0.7-0.70.7-0.9-0.60.7-0.8-0.70.70.70.70.8
Bone: post-yield work0.20.21.01.0-0.50.50.40.4-0.50.5-0.50.10.3-0.10.70.5-0.4-0.40.4-0.5-0.30.4-0.3-0.40.40.60.40.7
Progressive ratio test 1 active lever presses0.30.31.2-1.11.0-0.8-0.9-1.00.90.1-0.1-0.5-0.50.3-0.4-0.30.30.1-0.20.20.0-0.10.40.1-0.1-0.00.10.4
Progressive ratio test 1 breakpoint0.40.51.4-1.21.1-1.0-1.1-1.21.10.3-0.3-0.7-0.70.5-0.7-0.60.50.4-0.50.50.3-0.30.60.4-0.4-0.3-0.20.2
Progressive ratio test 1 inactive lever presses0.10.11.9-1.40.10.0-0.0-0.1-0.1-0.40.40.00.3-0.1-0.10.0-0.2-0.20.2-0.1-0.40.3-0.2-0.20.20.30.30.6
Progressive ratio test 2 active lever presses0.10.11.2-1.10.6-0.4-0.4-0.50.5-0.50.5-0.3-0.20.2-0.4-0.30.20.1-0.10.3-0.0-0.10.30.1-0.1-0.10.0-0.0
Progressive ratio test 2 breakpoint0.10.10.8-0.90.5-0.2-0.3-0.30.4-0.40.4-0.1-0.10.1-0.3-0.20.10.0-0.00.2-0.10.10.2-0.0-0.0-0.00.10.1
Progressive ratio test 2 inactive lever presses0.10.10.40.10.1-0.1-0.2-0.20.0-0.50.5-0.3-0.10.4-0.4-0.40.30.3-0.30.50.3-0.40.30.4-0.4-0.4-0.1-0.6
Incentive Sensitization - Responses0.10.10.9-0.9-0.20.50.40.4-0.3-0.50.50.30.3-0.1-0.10.1-0.2-0.10.2-0.1-0.30.2-0.2-0.10.20.10.00.2
Incentive Sensitization - Breakpoint0.20.20.7-0.9-0.50.70.70.7-0.6-0.50.50.50.6-0.30.20.3-0.4-0.40.4-0.3-0.50.5-0.5-0.30.30.40.20.5
Sum of active levers in priming session hrs 5-63.02.94.5-0.22.1-1.8-1.8-1.91.90.8-0.8-1.8-1.91.9-2.0-2.01.91.6-1.81.91.8-1.81.71.9-2.0-1.5-1.3-1.2
Progressive ratio0.30.31.0-0.4-0.20.10.10.2-0.20.4-0.4-0.1-0.20.5-0.6-0.60.60.8-0.60.60.6-0.60.20.9-1.0-1.0-0.5-0.9
Food seeking constrained by brief footshock0.70.81.3-0.7-1.01.11.11.1-1.0-0.80.81.01.1-0.60.80.9-0.9-0.71.0-0.9-1.01.0-0.9-0.70.40.90.91.0
Seeking ratio, punishment vs. effort0.40.42.0-0.10.3-0.1-0.1-0.20.2-0.50.50.10.4-0.40.70.7-0.7-0.80.7-0.7-0.80.8-0.2-0.90.81.20.91.4
Retroperitoneal fat weight0.41.43.10.2-1.31.41.41.4-1.41.3-1.31.00.9-1.11.21.2-1.0-0.91.0-1.4-1.01.1-0.9-1.11.01.20.51.8
Reaction time number correct0.20.31.40.70.0-0.1-0.1-0.10.10.5-0.5-0.2-0.40.5-0.3-0.40.40.6-0.50.40.6-0.60.20.6-0.7-0.8-0.8-1.2
Reaction time mean minus median0.40.61.6-0.31.1-1.2-1.3-1.21.1-0.30.3-1.1-0.70.8-0.6-0.60.50.5-0.50.70.5-0.51.00.2-0.2-0.2-0.5-0.6
Reaction time mean minus median AUC0.70.92.0-1.21.2-1.4-1.4-1.41.2-0.80.8-1.3-0.70.9-0.9-0.80.60.7-0.61.00.5-0.61.10.4-0.4-0.5-0.6-0.8
Reaction time num false alarms0.30.41.1-1.01.0-0.6-0.7-0.60.6-0.40.4-0.4-0.50.4-0.8-0.60.50.5-0.50.60.4-0.50.40.6-0.6-0.6-0.6-0.6
Reaction time num false alarms AUC0.30.41.2-0.91.1-0.7-0.7-0.70.7-0.20.2-0.5-0.60.5-0.8-0.70.60.6-0.60.70.5-0.60.50.7-0.7-0.8-0.6-0.6
Reaction time trials correct on left0.20.31.40.70.0-0.1-0.1-0.10.10.5-0.5-0.2-0.40.5-0.3-0.40.40.6-0.50.40.6-0.60.20.6-0.7-0.8-0.8-1.2
Reaction time trials on left0.20.31.40.60.1-0.2-0.2-0.20.10.4-0.4-0.2-0.40.5-0.3-0.40.40.6-0.50.40.6-0.60.20.6-0.7-0.8-0.8-1.2
Reaction time mean0.20.21.2-0.20.5-0.5-0.5-0.50.4-1.11.1-0.40.1-0.00.20.2-0.3-0.40.3-0.0-0.30.30.2-0.60.70.70.50.1
Reaction time mean AUC0.20.20.9-0.10.7-0.6-0.6-0.60.5-1.01.0-0.40.00.10.20.2-0.2-0.30.20.0-0.30.20.3-0.50.60.60.50.1
Median of all reaction times0.40.52.2-0.4-0.00.10.00.0-0.1-1.51.50.20.6-0.50.50.6-0.7-0.80.7-0.4-0.70.7-0.3-0.80.91.01.00.4
Reaction time omissions0.10.21.2-1.10.5-0.6-0.6-0.60.5-0.40.4-0.5-0.10.3-0.1-0.1-0.0-0.00.10.1-0.20.20.3-0.20.30.50.10.6
Reaction time false alarm rate0.10.11.3-1.10.8-0.4-0.4-0.40.5-0.50.5-0.2-0.20.0-0.4-0.30.20.1-0.10.20.0-0.10.20.1-0.1-0.1-0.00.1
Reaction time premature initiation rate0.40.51.1-1.01.0-1.0-1.0-1.01.00.5-0.5-0.7-0.70.6-0.8-0.70.60.6-0.60.60.5-0.50.80.5-0.5-0.5-0.5-0.0
Reaction time premature initiations0.70.91.4-0.41.2-1.2-1.2-1.21.10.8-0.8-0.9-1.01.0-1.0-0.91.01.0-1.00.90.9-0.90.90.9-0.9-1.0-1.1-0.8
Std. dev. reaction times0.30.41.2-0.51.0-1.0-1.1-1.10.9-0.40.4-0.9-0.50.6-0.4-0.40.30.3-0.30.50.2-0.30.7-0.10.00.0-0.3-0.3
Reaction time trials completed0.20.31.40.60.1-0.2-0.2-0.20.10.4-0.4-0.2-0.40.5-0.3-0.40.40.6-0.50.40.6-0.60.20.6-0.7-0.8-0.8-1.2
Reaction time trials AUC0.20.31.50.50.1-0.2-0.2-0.20.20.4-0.4-0.2-0.40.5-0.4-0.40.50.7-0.50.40.6-0.60.30.7-0.7-0.8-0.9-1.2
Run reversals in cocaine runway, females0.40.42.11.40.9-0.5-0.5-0.60.71.3-1.3-0.5-0.70.30.0-0.20.40.1-0.40.10.5-0.40.40.3-0.1-0.20.30.1
Run reversals in cocaine runway, males0.90.93.5-0.9-0.60.80.80.8-0.8-1.91.90.80.9-0.90.60.8-0.9-0.80.9-0.6-0.90.8-0.9-0.80.90.50.70.0
Latency to leave start box in cocaine runway2.52.64.11.7-2.02.02.02.0-2.0-0.80.81.71.6-1.62.01.8-1.6-1.51.6-1.7-1.41.4-1.6-1.61.51.61.40.8
Latency to leave start box in cocaine runway, F3.74.06.01.4-2.52.42.32.4-2.4-0.80.82.02.0-2.12.42.3-2.1-2.02.0-2.3-1.81.9-2.0-2.12.11.91.71.3
Latency to leave start box in cocaine runway, M0.70.61.11.0-1.01.01.01.0-1.1-0.50.50.80.9-0.60.90.8-0.7-0.70.7-0.7-0.60.7-0.7-0.50.41.10.90.6
Std. dev. time between licks in bursts1.11.31.70.4-1.01.21.21.2-1.2-0.90.91.31.2-1.31.31.3-1.2-1.31.2-1.2-1.11.1-1.2-1.31.31.21.20.7
Total sessions with >9 infusions0.40.51.6-1.0-0.10.40.30.3-0.4-0.40.40.40.7-0.70.50.6-0.7-0.80.7-0.7-0.90.8-0.5-0.90.90.90.81.3
Short access day 1 total inactive lever presses3.03.35.8-1.41.7-1.7-1.7-1.61.50.5-0.5-1.9-1.52.1-2.4-2.22.02.1-1.92.31.8-1.91.82.2-2.2-2.1-1.7-1.6
Short access day 10 total inactive lever presses0.70.82.40.50.3-0.5-0.5-0.40.40.2-0.2-0.9-0.61.1-1.0-1.00.91.2-1.01.11.1-1.10.91.1-1.1-1.1-1.2-1.6
Short access day 1 total infusions0.00.00.1-0.40.1-0.2-0.2-0.20.1-0.20.2-0.30.10.1-0.2-0.10.10.0-0.10.20.0-0.10.20.0-0.00.10.20.1
Short access day 10 total infusions0.30.30.90.1-0.50.40.40.3-0.5-0.40.40.50.6-0.60.60.6-0.6-0.70.6-0.6-0.60.6-0.5-0.70.60.70.90.8
Short access total infusions0.00.00.10.10.0-0.0-0.1-0.10.00.0-0.00.00.1-0.10.10.1-0.1-0.20.1-0.1-0.10.1-0.1-0.20.20.20.30.3
Short access day 1 locomotion0.91.02.7-1.7-1.21.11.01.0-1.1-0.50.51.11.2-1.00.60.8-0.9-0.91.0-0.9-1.11.0-1.1-0.90.90.80.91.3
Short access day 10 total locomotion0.60.62.0-1.4-0.60.90.80.9-0.9-1.01.01.10.8-0.70.40.6-0.7-0.60.7-0.7-0.80.8-1.1-0.60.60.30.40.4
Short access total locomotion0.90.91.6-1.0-1.11.21.11.1-1.1-0.60.61.31.1-0.90.80.9-0.9-0.91.0-1.0-1.01.0-1.3-0.90.90.70.60.9
One hour access (0.3 mA shock)0.60.71.2-0.21.0-0.9-0.9-1.01.10.2-0.2-0.9-0.80.8-0.9-0.90.80.7-0.80.90.8-0.80.90.9-0.9-0.7-0.5-0.7
Compulsive drug intake7.17.210.0-0.23.1-3.0-3.0-3.13.12.2-2.2-3.2-2.92.7-2.8-2.82.82.6-2.82.82.7-2.73.02.7-2.7-2.3-2.3-1.7
One hour access (shock baseline)2.42.83.7-0.4-1.91.91.81.8-1.8-1.51.51.91.8-1.71.61.7-1.7-1.71.8-1.7-1.81.7-1.8-1.71.61.51.61.3
Social response proportion0.70.71.4-0.71.0-0.9-0.9-0.90.91.2-1.2-0.9-0.90.9-0.9-0.90.90.8-0.90.70.8-0.80.80.8-0.7-0.7-0.8-0.0
Social responses0.00.00.4-0.60.3-0.3-0.3-0.30.20.0-0.0-0.1-0.20.1-0.2-0.20.20.0-0.10.10.0-0.1-0.10.1-0.10.10.00.3
Social time0.10.11.2-0.20.0-0.3-0.3-0.30.3-1.11.1-0.1-0.00.0-0.0-0.0-0.0-0.20.10.1-0.10.0-0.10.0-0.00.30.4-0.1
Soleus weight0.92.84.6-1.2-2.11.81.81.8-1.8-0.70.71.81.7-1.61.51.6-1.7-1.61.7-1.8-1.81.8-1.7-1.61.61.71.32.0
Bone: stiffness0.10.10.4-0.4-0.20.40.40.4-0.40.4-0.40.20.30.10.30.3-0.3-0.20.3-0.4-0.30.4-0.1-0.30.30.20.10.7
Tibialis anterior weight0.41.44.52.11.4-1.1-1.0-1.01.11.8-1.8-1.1-1.20.9-0.5-0.70.91.1-1.00.71.2-1.11.00.8-0.9-1.0-1.4-1.3
Time to tail flick, vehicle, before self-admin1.71.73.5-0.11.3-1.5-1.5-1.51.40.4-0.4-1.4-1.31.9-1.4-1.51.41.3-1.41.61.4-1.41.41.5-1.4-0.9-0.9-0.8
Time to tail flick, vehicle, after self-admin0.20.20.7-0.3-0.80.40.40.5-0.5-0.80.80.20.5-0.20.30.3-0.4-0.40.3-0.3-0.30.3-0.2-0.20.30.30.60.1
Time to tail flick, test, before self-admin0.10.10.70.8-0.30.20.20.3-0.30.2-0.20.40.2-0.10.30.2-0.1-0.10.1-0.10.00.0-0.50.10.00.10.1-0.0
Time to tail flick, test, after self-admin0.10.10.90.3-0.2-0.0-0.00.00.00.4-0.40.00.2-0.20.40.4-0.3-0.40.3-0.4-0.30.4-0.2-0.40.30.80.60.9
Delta time to tail flick, vehicle, before/after SA1.41.32.1-0.8-1.41.31.31.3-1.3-0.90.91.21.3-1.41.01.1-1.2-1.11.2-1.2-1.21.2-1.2-1.11.10.91.01.0
Delta time to tail flick, test, before/after SA0.30.21.1-1.10.4-0.5-0.5-0.50.50.8-0.8-0.6-0.40.2-0.5-0.40.30.3-0.30.30.1-0.20.50.2-0.4-0.0-0.00.7
Tibia length0.41.02.91.7-1.40.90.80.8-0.81.1-1.10.80.6-0.81.31.2-0.9-0.80.9-1.3-0.80.9-0.7-1.11.11.00.51.1
Ambulatory time before self-admin0.30.30.90.10.4-0.5-0.5-0.50.50.6-0.6-0.5-0.60.4-0.5-0.50.60.5-0.60.50.6-0.60.40.4-0.6-1.0-0.4-0.8
Ambulatory time after self-admin1.61.83.41.8-1.01.11.11.1-1.1-0.20.21.10.9-1.61.81.7-1.4-1.61.4-1.7-1.31.4-1.1-1.61.51.51.51.1
Bone: tissue strength0.10.10.70.8-0.30.20.20.2-0.2-0.20.20.10.2-0.40.50.4-0.3-0.30.3-0.4-0.30.3-0.3-0.20.20.50.40.1
Total heroin consumption1.61.92.8-0.11.7-1.5-1.5-1.51.50.2-0.2-1.6-1.31.7-1.5-1.51.41.4-1.41.61.3-1.41.51.5-1.5-1.3-1.0-1.5
Bone: trabecular number0.91.46.5-2.6-1.01.21.21.2-1.2-1.51.51.01.4-0.80.50.7-1.0-1.01.1-0.7-1.31.2-0.9-0.90.90.91.21.4
Bone: trabecular spacing0.10.10.90.70.2-0.2-0.2-0.20.2-0.40.4-0.0-0.3-0.1-0.0-0.00.10.1-0.20.10.3-0.20.00.1-0.1-0.3-0.4-0.9
Bone: trabecular thickness1.41.73.70.1-1.11.41.41.4-1.40.2-0.21.41.2-1.31.41.4-1.3-1.31.3-1.5-1.31.4-1.4-1.31.31.51.41.9
Bone: trabecular tissue density0.10.20.4-0.30.2-0.4-0.4-0.40.40.2-0.2-0.2-0.40.3-0.4-0.40.40.5-0.40.40.4-0.40.20.5-0.5-0.6-0.6-0.6
Water consumed over 24 hours0.20.30.4-0.10.5-0.7-0.7-0.70.70.0-0.0-0.5-0.50.5-0.5-0.50.50.5-0.50.60.5-0.50.40.6-0.6-0.5-0.5-0.5
Number of responses in last shaping day0.10.10.70.20.20.00.0-0.1-0.0-0.80.80.10.2-0.10.20.1-0.1-0.10.1-0.0-0.10.1-0.1-0.20.2-0.00.1-0.5