Hub : Genes

LOC102547155

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h2	h2 SE	h2 P	xQTL R2	BLUP R2	ENET R2	LASSO R2	xQTL P	BLUP P	ENET P	LASSO P
1	Brain	gene expression	LOC102547155	0.03	0.03	2.2e-03	0.02	0.02	0.02	0.02	6.2e-03	3.6e-03	3.2e-03	4.8e-03
2	PL	gene expression	LOC102547155	0.17	0.1	0.0e+00	0.2	0.2	0.19	0.19	1.3e-21	2.9e-21	1.6e-20	6.9e-21
3	BLA	gene expression	LOC102547155	0.18	0.13	9.9e-07	0.1	0.11	0.1	0.11	5.8e-06	1.9e-06	4.6e-06	2.1e-06
4	IL	gene expression	LOC102547155	0.33	0.17	1.1e-06	0.18	0.19	0.16	0.17	3.9e-05	3.1e-05	1.0e-04	5.4e-05
5	NAcc	gene expression	LOC102547155	0.03	0.02	1.2e-04	0.03	0.04	0.03	0.03	3.1e-04	4.4e-05	2.6e-04	2.2e-04
6	OFC	gene expression	LOC102547155	0.28	0.16	1.3e-06	0.28	0.28	0.29	0.29	2.7e-07	2.9e-07	1.6e-07	1.2e-07

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6
Bone: apparent density	0.6	1.1	1.9	-1.4	-1.0	0.9	1.0	1.0	0.8
Area under the delay curve	1.1	1.1	1.7	1.0	1.3	-1.1	-1.1	-1.1	-0.8
BMI with tail	2.1	6.9	9.1	3.0	2.8	-2.5	-2.6	-2.6	-2.2
BMI without tail	1.3	2.7	3.4	1.9	1.6	-1.6	-1.7	-1.7	-1.5
Body weight	6.6	27.5	29.7	5.4	5.2	-5.2	-5.3	-5.3	-5.0
Weight adjusted by age	1.5	1.7	4.4	2.1	1.0	-0.9	-1.2	-1.2	-1.0
Bone surface	0.0	0.0	0.0	-0.0	-0.0	0.0	-0.0	0.0	-0.1
Bone volume	0.0	0.0	0.1	-0.1	0.1	-0.2	-0.1	-0.1	-0.2
Breakpoint value in progressive ratio session	0.3	0.3	0.4	-0.5	-0.7	0.6	0.6	0.6	0.5
Number of licking bursts	0.6	0.7	0.8	-0.8	-0.9	0.8	0.8	0.8	0.7
Context. condit. distance diff. score	0.2	0.3	0.6	-0.4	-0.4	0.6	0.6	0.6	0.7
Locomotion velocity, session 1	0.7	0.7	0.9	-1.0	-0.9	0.8	0.8	0.8	0.8
Locomotion distance, session 1	3.3	4.3	4.5	-2.0	-2.0	2.1	2.1	2.1	2.1
Locomotion velocity, session 2	0.2	0.3	0.3	-0.5	-0.5	0.5	0.5	0.5	0.5
Locomotion distance, session 2	0.8	1.1	1.3	-1.0	-1.0	1.1	1.1	1.1	1.1
Locomotion velocity, session 3	0.4	0.4	0.7	0.2	0.6	-0.8	-0.7	-0.7	-0.8
Locomotion distance, session 3	0.3	0.3	0.6	-0.8	-0.4	0.4	0.5	0.5	0.5
Stereotopy head waving bouts, day 3	2.0	2.3	2.4	1.5	1.5	-1.5	-1.5	-1.5	-1.5
Stereotopy head waving duration, day 3	0.2	0.2	0.5	0.7	0.4	-0.3	-0.4	-0.4	-0.3
Locomotion velocity, session 7	0.1	0.1	0.4	-0.6	-0.1	0.0	0.1	0.2	0.1
Locomotion distance, session 7	0.9	1.2	1.9	-1.4	-1.0	0.9	1.0	1.1	1.0
Stereotopy head waving bouts, day 7	0.4	0.5	0.6	0.4	0.7	-0.8	-0.7	-0.7	-0.8
Stereotopy head waving duration, day 7	1.2	1.5	1.9	0.9	1.2	-1.3	-1.2	-1.2	-1.4
Locomotion velocity, session 8	0.0	0.0	0.0	-0.0	0.1	-0.0	0.0	0.0	0.1
Locomotion distance, session 8	0.8	1.1	1.4	-0.9	-0.9	1.1	1.1	1.1	1.2
Degree of sensitization distance	0.0	0.0	0.0	0.1	-0.1	0.1	0.1	0.1	0.1
Degree of sensitization stereotypy	0.0	0.0	0.2	-0.5	-0.1	-0.1	-0.0	0.0	-0.2
Conditioned locomotion	2.6	3.0	3.7	1.5	1.6	-1.8	-1.8	-1.8	-1.9
Cocaine response after cond. corrected	1.0	1.1	2.8	1.7	1.1	-0.8	-0.9	-1.0	-0.7
Cocaine response after cond. not corrected	1.0	1.1	2.4	1.5	1.1	-0.8	-0.9	-1.0	-0.7
Cocaine response before conditioning	0.0	0.0	0.2	-0.5	-0.0	-0.1	0.0	0.0	-0.1
Saline control response	0.6	0.8	0.9	0.8	0.9	-0.9	-0.9	-0.9	-0.8
Bone: connectivity density	0.5	0.8	1.3	-1.1	-0.9	0.8	0.9	0.9	0.7
Bone: cortical apparent density	0.0	0.0	0.2	-0.4	-0.0	-0.1	0.0	0.0	-0.1
Bone: cortical area	0.4	0.6	1.2	1.1	0.9	-0.7	-0.7	-0.7	-0.4
Bone: cortical porosity	0.0	0.0	0.1	0.2	0.0	0.0	-0.0	-0.0	0.0
Bone: cortical porosity	0.0	0.0	0.0	0.2	0.0	0.1	0.0	0.0	0.1
Bone: cortical thickness	0.1	0.1	0.2	-0.1	-0.2	0.3	0.3	0.3	0.5
Bone: cortical thickness	0.0	0.0	0.1	0.0	0.2	-0.2	-0.1	-0.1	-0.1
Bone: cortical tissue density	0.0	0.0	0.1	-0.3	0.0	-0.2	-0.1	-0.1	-0.2
Condit. Reinf. active minus inactive responses	0.9	1.0	1.4	-1.2	-1.0	0.9	1.0	1.0	0.9
Condit. Reinf. active-inactive response ratio	0.0	0.1	0.1	-0.2	-0.1	0.2	0.2	0.2	0.3
Condit. Reinf. active responses	0.3	0.3	0.9	-0.9	-0.6	0.4	0.5	0.5	0.3
Condit. Reinf. inactive responses	0.3	0.4	1.1	-1.1	-0.7	0.4	0.5	0.6	0.3
Incentive salience index mean	0.4	0.4	0.7	-0.8	-0.7	0.6	0.6	0.6	0.5
Condit. Reinf. lever presses	0.0	0.0	0.1	-0.2	-0.2	0.2	0.2	0.2	0.2
Condit. Reinf. active minus inactive responses	0.8	1.0	1.2	-0.9	-1.1	1.0	1.0	1.0	0.9
Condit. Reinf. active-inactive response ratio	0.4	0.4	0.7	-0.3	-0.9	0.7	0.6	0.6	0.5
Condit. Reinf. active responses	0.7	0.9	1.2	-1.1	-0.9	0.9	1.0	1.0	1.0
Condit. Reinf. inactive responses	0.1	0.1	0.2	-0.2	0.5	-0.4	-0.2	-0.2	-0.1
Condit. Reinf. lever presses	3.6	4.9	5.9	-2.4	-1.9	2.1	2.2	2.2	2.4
Condit. Reinf. lever reinforcers received	1.4	2.0	2.2	-1.5	-1.3	1.4	1.4	1.4	1.5
Conditioned reinforcement - actives	0.6	0.6	0.8	0.9	0.8	-0.8	-0.8	-0.8	-0.8
Conditioned reinforcement - inactives	0.2	0.2	0.4	-0.6	-0.4	0.3	0.4	0.4	0.3
Conditioned locomotion	0.6	0.8	0.8	0.9	0.9	-0.8	-0.9	-0.9	-0.8
Patch foraging indifference point 0 sec	0.3	0.5	0.5	0.7	0.7	-0.7	-0.7	-0.7	-0.6
Patch foraging indifference point AUC	0.0	0.0	0.1	-0.3	0.0	0.1	0.2	0.2	0.1
Delay disc. indifference point, 0s delay	0.3	0.3	0.8	0.9	0.6	-0.3	-0.4	-0.4	-0.2
Delay disc. indifference point, 16s delay	0.2	0.2	0.5	-0.0	0.7	-0.6	-0.5	-0.4	-0.4
Delay disc. indifference point, 2s delay	0.1	0.1	0.2	0.2	-0.2	0.3	0.2	0.2	0.4
Delay disc. indifference point, 24s delay	2.8	2.7	3.6	1.5	1.9	-1.7	-1.7	-1.6	-1.3
Delay disc. indifference point, 4s delay	1.5	1.5	2.2	1.2	1.5	-1.2	-1.2	-1.2	-1.0
Delay disc. indifference point, 8s delay	1.9	2.0	2.6	1.2	1.6	-1.5	-1.4	-1.4	-1.2
Indifference point function ln k	0.1	0.2	0.3	-0.3	-0.6	0.4	0.4	0.4	0.3
Indifference point function log k	0.1	0.2	0.3	-0.3	-0.6	0.4	0.4	0.4	0.3
Patch foraging total patch changes 0 sec	0.2	0.4	0.4	0.6	0.6	-0.6	-0.6	-0.6	-0.6
Patch foraging total patch changes 12 sec	0.0	0.0	0.0	0.1	0.1	0.1	0.1	0.0	0.1
Patch foraging total patch changes 18 sec	0.6	0.8	1.2	0.5	1.1	-1.0	-0.9	-0.9	-0.9
Patch foraging total patch changes 24 sec	0.3	0.4	0.5	-0.4	-0.5	0.7	0.6	0.6	0.7
Patch foraging total patch changes 6 sec	0.1	0.1	0.1	0.3	0.4	-0.3	-0.3	-0.3	-0.2
Patch foraging time to switch 0 sec	1.3	2.0	2.7	1.6	1.5	-1.3	-1.4	-1.4	-1.3
Patch foraging water rate 0 sec	0.2	0.4	0.5	-0.4	-0.7	0.7	0.6	0.6	0.6
Patch foraging water rate 12 sec	0.1	0.2	0.3	-0.5	-0.4	0.4	0.5	0.5	0.5
Patch foraging water rate 18 sec	0.6	0.9	1.6	-1.3	-0.8	0.8	0.9	0.9	0.8
Patch foraging water rate 24 sec	0.4	0.5	0.7	-0.8	-0.6	0.6	0.7	0.7	0.8
Patch foraging water rate 6 sec	0.2	0.3	0.5	-0.4	-0.5	0.5	0.5	0.5	0.7
Seeking ratio, delayed vs. immediate footshock	0.1	0.1	0.7	-0.8	0.1	-0.2	0.0	0.1	-0.1
Distance traveled before self-admin	0.8	0.9	1.0	1.0	0.8	-0.9	-0.9	-0.9	-1.0
Distance traveled after self-admin	0.0	0.0	0.1	0.2	-0.0	-0.1	-0.2	-0.2	-0.4
Extensor digitorum longus weight	0.2	0.8	0.8	-0.8	-0.9	0.9	0.9	0.9	0.9
Bone: elastic displacement	0.0	0.0	0.0	-0.2	-0.2	0.2	0.2	0.2	0.2
Bone: elastic work	0.0	0.0	0.1	0.3	0.3	-0.1	-0.2	-0.2	0.1
Bone: endosteal estimation	3.6	7.9	8.9	2.8	3.0	-2.8	-2.8	-2.8	-2.6
Bone: endosteal perimeter	2.1	4.3	5.6	2.4	2.1	-1.9	-2.0	-2.1	-1.9
Epididymis fat weight	1.6	3.8	5.4	2.3	2.0	-1.8	-1.9	-2.0	-1.7
Delta time in closed arm before/after self-admin	1.9	1.8	3.7	1.9	1.1	-1.1	-1.3	-1.3	-1.2
Delta time in open arm before/after self-admin	0.8	0.7	1.1	-1.0	-0.7	0.8	0.9	0.9	0.9
Diff in mean of infusions in LGA sessions	1.0	1.1	1.2	-0.9	-1.1	1.1	1.0	1.0	1.1
Delay discount exponential model param	0.8	0.9	1.4	-0.8	-1.2	1.0	1.0	0.9	0.7
Extinction: sum of active levers before priming	0.2	0.2	0.5	0.3	-0.7	0.6	0.4	0.4	0.4
Active lever presses in extinction session 6	0.1	0.1	0.3	0.1	0.5	-0.2	-0.2	-0.2	0.0
Bone: final force	4.7	7.6	8.7	2.8	2.9	-2.7	-2.7	-2.7	-2.5
Bone: final moment	4.0	6.5	8.0	2.6	2.8	-2.5	-2.5	-2.5	-2.2
Food consumed during 24 hour testing period	0.5	0.6	1.0	1.0	0.8	-0.7	-0.7	-0.8	-0.6
Glucose	0.1	0.1	0.5	0.7	0.2	-0.0	-0.1	-0.2	0.1
Heart weight	2.3	3.2	3.9	-1.5	-1.7	2.0	1.9	1.8	1.9
Delay discount hyperbolic model param	0.6	0.6	0.9	-0.7	-1.0	0.8	0.8	0.8	0.5
Intermittent access intake day 1-15 change	0.7	0.7	1.3	0.0	0.7	-1.0	-0.8	-0.8	-1.1
Intermittent access intake escalation	1.2	1.1	1.9	0.3	1.0	-1.3	-1.1	-1.0	-1.4
Intermittent access intake escalation 2	0.2	0.2	0.7	-0.8	-0.5	0.1	0.2	0.3	-0.2
Intermitt. access day 1 inactive lever presses	0.1	0.1	0.2	0.5	-0.3	0.4	0.2	0.2	0.3
Intermitt. access day 15 inactive lever presses	1.1	1.2	1.9	0.6	0.9	-1.2	-1.1	-1.1	-1.4
Intermitt. access escalation Index	0.4	0.4	0.4	-0.6	-0.6	0.6	0.6	0.6	0.6
Intermittent access day 1 total infusions	0.3	0.3	0.4	-0.6	-0.6	0.5	0.6	0.6	0.6
Intermittent access day 15 total infusions	0.1	0.1	0.2	-0.1	0.2	-0.4	-0.3	-0.3	-0.4
Intermittent access terminal intake (last 3 days)	0.2	0.2	0.3	0.3	0.3	-0.4	-0.4	-0.4	-0.6
Intermittent access total infusions	0.1	0.1	0.1	-0.4	-0.3	0.2	0.2	0.2	0.1
Intermittent access day 1 locomotion	0.1	0.2	0.2	0.5	0.3	-0.4	-0.4	-0.4	-0.4
Intermittent access day 15 total locomotion	4.4	4.7	6.4	1.6	2.0	-2.4	-2.2	-2.2	-2.5
Intermittent access total locomotion	1.6	1.8	2.5	0.8	1.3	-1.5	-1.4	-1.4	-1.6
Intermittent access standard deviation	0.9	0.9	1.1	1.1	0.8	-0.9	-1.0	-1.0	-1.0
Left kidney weight	3.0	8.4	9.5	2.8	2.8	-2.9	-2.9	-2.9	-3.1
Right kidney weight	3.8	10.8	12.0	3.0	3.2	-3.4	-3.3	-3.3	-3.5
Cocaine induced anxiety	0.1	0.2	0.7	-0.8	-0.4	0.1	0.3	0.3	0.1
Post-drug Anxiety	0.4	0.4	0.7	-0.8	-0.8	0.6	0.6	0.6	0.4
Baseline Anxiety	0.2	0.2	0.4	0.3	-0.5	0.6	0.5	0.4	0.6
Tail length	1.1	3.4	4.2	1.7	1.5	-1.9	-1.9	-1.9	-2.1
Length with tail	2.4	8.7	10.1	2.7	2.7	-3.0	-3.0	-3.0	-3.2
Length without tail	1.8	4.0	4.1	1.9	2.0	-2.0	-2.0	-2.0	-2.0
Times rat made contact with spout	3.2	3.7	5.0	-2.2	-1.9	1.8	1.9	1.9	1.7
Lifetime Intake	0.0	0.0	0.1	0.2	0.1	-0.2	-0.2	-0.2	-0.3
Liver weight, left	5.2	8.3	9.6	2.2	3.0	-3.1	-2.9	-2.9	-3.0
Liver weight, right	2.4	4.1	4.6	1.7	2.0	-2.1	-2.1	-2.0	-2.1
Locomotor activity	0.1	0.2	0.2	0.1	0.5	-0.5	-0.4	-0.4	-0.5
Locomotor testing distance	0.0	0.0	0.0	0.2	0.1	-0.0	-0.0	-0.1	0.0
Locomotor testing rearing	0.9	1.4	1.6	1.2	1.2	-1.2	-1.2	-1.2	-1.1
Locomotion in novel chamber	0.5	0.6	1.1	-0.5	-0.8	0.8	0.7	0.7	1.0
Locomotion in novel chamber post-restriction	2.0	2.4	2.6	1.6	1.4	-1.6	-1.6	-1.6	-1.5
Fecal boli incidents, locomotor time 1	0.0	0.0	0.0	0.0	0.1	-0.1	-0.1	-0.1	0.1
Change in fecal boli incidents, locomotor task	0.6	0.5	2.6	1.6	0.4	-0.1	-0.4	-0.5	-0.2
Time >=10cm from walls, locomotor time 1	1.7	1.7	3.1	1.8	1.1	-1.1	-1.3	-1.3	-1.2
Bouts of movement, locomotor time 1	0.2	0.3	0.3	-0.6	-0.6	0.4	0.5	0.5	0.4
Total resting periods, locomotor time 1	0.1	0.1	0.2	-0.4	-0.3	0.1	0.2	0.2	0.2
Rest time, locomotor task time 1	0.2	0.2	0.4	0.6	0.4	-0.3	-0.4	-0.4	-0.4
Distance moved, locomotor task time 1	0.1	0.1	0.2	0.1	0.3	-0.4	-0.3	-0.3	-0.5
Vertical activity count, locomotor time 1	0.6	0.6	0.9	0.6	0.8	-0.8	-0.8	-0.8	-0.9
Time >=10cm from walls, locomotor time 2	6.9	7.3	12.0	3.5	2.5	-2.4	-2.6	-2.7	-2.4
Bouts of movement, locomotor time 2	0.1	0.1	0.2	0.0	0.2	-0.4	-0.3	-0.3	-0.4
Total resting periods, locomotor time 2	0.0	0.0	0.1	-0.2	-0.2	0.1	0.1	0.2	0.1
Rest time, locomotor task time 2	0.0	0.0	0.1	0.3	0.2	0.0	-0.1	-0.1	0.1
Distance moved, locomotor task time 2	2.3	2.7	3.8	1.5	1.5	-1.6	-1.6	-1.6	-2.0
Vertical activity count, locomotor time 2	1.3	1.5	2.3	1.2	1.0	-1.2	-1.2	-1.2	-1.5
Light reinforcement 1	2.0	3.6	4.0	2.0	1.7	-1.9	-1.9	-2.0	-1.9
Light reinforcement 2	2.6	3.4	3.7	1.7	1.9	-1.9	-1.9	-1.9	-1.8
Bone: marrow area	3.7	8.1	9.2	2.9	3.0	-2.8	-2.8	-2.8	-2.7
Bone: maximum diameter	0.5	1.0	1.7	1.3	1.1	-0.8	-0.9	-0.9	-0.7
Bone: maximum force	1.8	3.1	3.9	1.8	2.0	-1.8	-1.8	-1.8	-1.6
Bone: maximum moment	1.4	2.4	3.2	1.6	1.8	-1.5	-1.5	-1.5	-1.2
Mean time between licks in bursts	0.5	0.8	0.9	-0.9	-0.9	0.9	0.9	0.9	0.8
Mean num. licks in bursts	0.2	0.3	0.5	-0.7	-0.4	0.4	0.5	0.5	0.5
Cd content in liver	1.1	1.2	1.4	0.7	1.1	-1.2	-1.1	-1.1	-1.2
Co content in liver	2.4	2.8	3.2	1.8	1.6	-1.6	-1.7	-1.7	-1.7
Cu content in liver	3.5	4.2	4.5	-2.0	-2.1	2.1	2.1	2.1	2.0
Fe content in liver	4.2	5.0	5.9	1.9	2.2	-2.3	-2.3	-2.3	-2.4
K content in liver	1.2	1.2	1.5	-0.9	-1.2	1.2	1.1	1.1	1.0
Mg content in liver	2.5	2.6	3.1	-1.1	-1.7	1.8	1.6	1.6	1.7
Mn content in liver	0.1	0.1	0.1	-0.0	-0.3	0.4	0.3	0.3	0.3
Na content in liver	0.2	0.2	0.5	-0.4	-0.7	0.3	0.3	0.3	-0.0
Rb content in liver	0.2	0.2	0.4	0.6	0.4	-0.4	-0.4	-0.4	-0.3
Se content in liver	2.9	3.5	4.0	-1.6	-2.0	2.0	1.9	1.9	1.8
Sr content in liver	0.0	0.0	0.0	-0.0	-0.1	0.2	0.1	0.1	0.2
Zn content in liver	1.4	1.5	3.6	1.9	1.5	-0.9	-1.0	-1.1	-0.5
Bone: minimum diameter	1.6	3.0	5.1	2.3	1.9	-1.5	-1.7	-1.7	-1.3
Time in familiar zone, hab. session 1	0.0	0.0	0.1	-0.3	0.0	0.0	0.1	0.1	0.1
Time in novel zone, hab. session 1	0.4	0.3	0.5	0.7	0.6	-0.5	-0.6	-0.6	-0.6
Total zone transitions, hab. session 1	2.8	4.0	4.7	-2.0	-2.2	2.0	2.0	2.0	1.8
Total locomotion distance, hab. session 1	1.9	2.8	3.1	-1.6	-1.8	1.7	1.7	1.7	1.6
Locomotion velocity, hab. session 1	1.9	2.6	3.1	-1.5	-1.8	1.7	1.6	1.6	1.6
Time in familiar zone, hab. session 2	1.3	1.3	1.6	-1.2	-1.1	1.1	1.2	1.2	1.3
Time in novel zone, hab. session 2	1.6	1.6	1.8	1.1	1.3	-1.3	-1.3	-1.3	-1.3
Total zone transitions, hab. session 2	0.4	0.5	0.5	-0.6	-0.6	0.7	0.7	0.7	0.7
Total locomotion distance, hab. session 2	2.3	3.1	3.3	-1.7	-1.7	1.8	1.8	1.8	1.8
Locomotion velocity, hab. session 2	2.9	3.9	4.0	-1.9	-1.9	2.0	2.0	2.0	2.0
Novel to familiar place preference ratio	0.4	0.4	0.9	1.0	0.6	-0.5	-0.6	-0.6	-0.5
Novelty place preference	0.3	0.3	0.7	0.9	0.5	-0.4	-0.5	-0.6	-0.5
Time in novel zone, NPP test	0.4	0.4	0.8	0.9	0.6	-0.5	-0.6	-0.6	-0.6
Total zone transitions, NPP test	1.5	2.2	2.6	-1.4	-1.4	1.5	1.5	1.5	1.6
Total locomotion distance, NPP test	1.3	1.7	2.1	-1.1	-1.2	1.4	1.4	1.3	1.5
Locomotion velocity, NPP test	2.0	2.8	3.2	-1.4	-1.6	1.7	1.7	1.7	1.8
Intraocular pressure	1.3	1.8	2.5	0.8	1.6	-1.5	-1.4	-1.3	-1.3
Delta distance traveled before/after self-admin	0.6	0.7	0.8	-0.8	-0.9	0.8	0.8	0.8	0.8
Delta ambulatory time before/after self-admin	0.9	1.0	1.3	-1.1	-1.1	0.9	0.9	1.0	0.8
Parametrial fat weight	1.9	3.7	4.7	1.2	2.0	-2.2	-2.0	-1.9	-2.1
Pavlov. Cond. lever latency	0.4	0.5	0.5	0.6	0.7	-0.7	-0.7	-0.7	-0.6
Pavlov. Cond. magazine entry latency	0.4	0.5	0.9	-0.7	-0.4	0.7	0.7	0.7	0.9
Pavlov. Cond. change in total contacts	0.5	0.5	0.6	0.6	0.8	-0.8	-0.8	-0.7	-0.7
Pavlov. Cond. index score	0.1	0.1	0.3	-0.3	-0.1	0.4	0.4	0.4	0.6
Pavlov. Cond. latency score	0.1	0.1	0.2	-0.1	-0.1	0.3	0.3	0.3	0.5
Pavlov. Cond. lever contacts	0.2	0.3	0.3	-0.4	-0.5	0.6	0.5	0.5	0.6
Pavlov. Cond. magazine entry number	0.8	1.0	1.4	0.9	0.8	-1.0	-1.0	-1.0	-1.2
Pavlov. Cond. intertrial magazine entries	0.1	0.1	0.2	-0.3	-0.4	0.1	0.2	0.2	-0.1
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.1	0.3	-0.2	-0.1	0.3	0.3	0.3	0.5
Pavlov. Cond. response bias	0.9	1.1	1.3	-1.1	-0.9	1.1	1.1	1.1	1.2
Pavlov. Cond. lever latency	2.1	2.8	3.9	2.0	1.3	-1.5	-1.7	-1.7	-1.8
Pavlov. Cond. magazine entry latency	0.1	0.1	0.2	0.1	0.4	-0.5	-0.4	-0.4	-0.4
Pavlov. Cond. change in total contacts	1.4	1.9	2.7	-1.6	-1.2	1.3	1.4	1.4	1.4
Pavlov. Cond. index score	0.5	0.7	1.4	-1.2	-0.6	0.7	0.8	0.8	0.8
Pavlov. Cond. latency score	0.3	0.4	0.9	-0.9	-0.5	0.5	0.6	0.6	0.6
Pavlov. Cond. lever contacts	1.5	2.1	3.6	-1.9	-1.1	1.2	1.4	1.4	1.5
Pavlov. Cond. magazine entry number	0.0	0.0	0.1	0.2	-0.2	0.3	0.2	0.1	0.1
Pavlov. Cond. intertrial magazine entries	0.5	0.7	0.7	-0.8	-0.8	0.8	0.8	0.8	0.7
Pavlov. Cond. lever-magazine prob. diff.	0.3	0.4	0.9	-0.9	-0.4	0.4	0.5	0.6	0.6
Pavlov. Cond. response bias	0.9	1.2	2.6	-1.6	-0.7	0.8	1.0	1.1	1.1
Time in closed arm before self-admin	0.4	0.4	0.6	-0.2	-0.7	0.8	0.7	0.6	0.7
Time in closed arm after self-admin	0.2	0.2	0.7	0.8	0.3	-0.1	-0.3	-0.3	-0.1
Time in open arm before self-admin	0.5	0.5	1.6	-1.3	-0.7	0.4	0.6	0.6	0.3
Time in open arm after self-admin	2.3	2.5	4.9	-2.2	-1.5	1.3	1.5	1.5	1.3
Bone: periosteal estimation	2.5	5.1	6.2	2.5	2.4	-2.2	-2.2	-2.2	-2.0
Bone: periosteal perimeter	1.1	1.8	2.7	1.7	1.5	-1.2	-1.3	-1.3	-1.0
Bone: post-yield work	0.2	0.3	0.4	0.6	0.6	-0.6	-0.6	-0.6	-0.6
Progressive ratio test 1 active lever presses	0.0	0.0	0.0	0.2	-0.1	0.2	0.1	0.1	0.2
Progressive ratio test 1 breakpoint	0.0	0.0	0.1	0.3	-0.1	0.2	0.1	0.1	0.2
Progressive ratio test 1 inactive lever presses	0.8	0.9	0.9	0.9	0.9	-0.9	-0.9	-0.9	-1.0
Progressive ratio test 2 active lever presses	0.0	0.0	0.0	-0.1	-0.1	-0.0	0.0	0.0	-0.0
Progressive ratio test 2 breakpoint	0.0	0.0	0.0	-0.2	-0.1	0.1	0.1	0.1	0.1
Progressive ratio test 2 inactive lever presses	0.3	0.4	0.8	-0.9	-0.8	0.5	0.5	0.5	0.2
Incentive Sensitization - Responses	1.0	1.1	1.6	-1.3	-1.1	0.9	1.0	1.0	0.9
Incentive Sensitization - Breakpoint	0.6	0.6	1.2	-1.1	-0.8	0.6	0.7	0.7	0.6
Sum of active levers in priming session hrs 5-6	0.5	0.5	0.9	-0.4	-1.0	0.8	0.7	0.7	0.6
Progressive ratio	3.2	3.7	4.7	1.3	2.0	-2.1	-1.9	-1.9	-2.2
Food seeking constrained by brief footshock	0.1	0.1	0.2	-0.4	0.1	0.2	0.2	0.3	0.4
Seeking ratio, punishment vs. effort	2.0	2.4	3.5	-0.8	-1.4	1.8	1.6	1.5	1.9
Retroperitoneal fat weight	1.4	4.7	6.1	2.5	2.2	-2.0	-2.1	-2.2	-2.0
Reaction time number correct	0.6	0.8	1.1	0.3	1.0	-1.1	-0.9	-0.9	-1.0
Reaction time mean minus median	0.1	0.2	0.4	-0.4	0.3	-0.6	-0.4	-0.3	-0.6
Reaction time mean minus median AUC	0.1	0.2	0.3	-0.2	0.4	-0.6	-0.4	-0.4	-0.5
Reaction time num false alarms	0.2	0.2	0.5	-0.6	-0.7	0.4	0.4	0.4	0.1
Reaction time num false alarms AUC	0.7	1.0	1.6	-1.0	-1.3	1.0	1.0	1.0	0.7
Reaction time trials correct on left	0.6	0.8	1.1	0.3	1.0	-1.1	-0.9	-0.9	-1.0
Reaction time trials on left	0.5	0.8	1.1	0.3	1.0	-1.0	-0.9	-0.9	-0.9
Reaction time mean	0.2	0.3	0.4	0.5	0.6	-0.6	-0.6	-0.5	-0.5
Reaction time mean AUC	0.5	0.7	0.9	0.7	1.0	-0.9	-0.9	-0.9	-0.8
Median of all reaction times	0.3	0.5	0.6	0.8	0.8	-0.6	-0.6	-0.6	-0.5
Reaction time omissions	0.1	0.1	0.3	-0.6	-0.0	-0.2	-0.1	-0.0	-0.3
Reaction time false alarm rate	1.4	2.0	3.1	-1.0	-1.8	1.5	1.4	1.4	1.2
Reaction time premature initiation rate	0.2	0.2	0.6	-0.1	-0.8	0.6	0.5	0.5	0.4
Reaction time premature initiations	0.0	0.0	0.1	0.2	-0.0	-0.2	-0.2	-0.2	-0.3
Std. dev. reaction times	0.0	0.0	0.1	-0.3	0.1	-0.2	-0.1	-0.1	-0.3
Reaction time trials completed	0.5	0.8	1.1	0.3	1.0	-1.0	-0.9	-0.9	-0.9
Reaction time trials AUC	0.5	0.8	1.1	0.3	1.0	-1.0	-0.9	-0.9	-0.9
Run reversals in cocaine runway, females	0.2	0.2	0.3	-0.1	0.6	-0.6	-0.4	-0.4	-0.4
Run reversals in cocaine runway, males	0.3	0.3	1.0	-1.0	0.0	-0.5	-0.2	-0.2	-0.5
Latency to leave start box in cocaine runway	0.5	0.6	0.9	0.7	-0.8	0.9	0.6	0.6	0.9
Latency to leave start box in cocaine runway, F	0.4	0.4	0.8	0.6	-0.4	0.9	0.6	0.5	0.9
Latency to leave start box in cocaine runway, M	0.1	0.1	0.2	0.5	-0.4	0.2	0.1	0.0	0.1
Std. dev. time between licks in bursts	0.6	0.7	2.5	1.6	0.8	-0.3	-0.6	-0.6	-0.2
Total sessions with >9 infusions	0.1	0.1	0.2	0.5	0.2	-0.1	-0.2	-0.2	-0.0
Short access day 1 total inactive lever presses	0.1	0.1	0.3	-0.2	-0.5	0.3	0.3	0.3	0.1
Short access day 10 total inactive lever presses	0.0	0.0	0.0	0.0	-0.1	-0.1	-0.1	-0.1	-0.1
Short access day 1 total infusions	0.9	0.9	1.1	-0.6	-1.0	1.1	1.0	1.0	1.0
Short access day 10 total infusions	0.0	0.0	0.1	-0.1	-0.3	0.2	0.1	0.1	0.0
Short access total infusions	0.0	0.0	0.2	0.4	-0.0	0.0	-0.1	-0.1	-0.0
Short access day 1 locomotion	0.1	0.1	0.3	0.5	-0.1	0.4	0.2	0.1	0.4
Short access day 10 total locomotion	0.5	0.5	0.9	0.5	-0.8	1.0	0.7	0.6	0.8
Short access total locomotion	0.1	0.2	0.9	0.9	-0.1	0.2	-0.1	-0.1	0.0
One hour access (0.3 mA shock)	0.9	1.0	1.2	-1.1	-1.0	1.0	1.0	1.0	0.9
Compulsive drug intake	2.7	2.7	3.7	-0.8	-1.9	1.9	1.7	1.6	1.7
One hour access (shock baseline)	0.2	0.3	0.5	-0.4	0.5	-0.7	-0.5	-0.4	-0.6
Social response proportion	0.1	0.1	0.3	0.6	0.1	0.0	-0.1	-0.1	0.1
Social responses	0.1	0.1	0.2	0.3	-0.2	0.3	0.2	0.2	0.4
Social time	0.2	0.3	0.4	-0.6	-0.7	0.5	0.5	0.5	0.4
Soleus weight	0.4	1.1	2.6	1.6	0.9	-0.8	-0.9	-1.0	-0.8
Bone: stiffness	1.4	2.2	2.9	1.4	1.7	-1.5	-1.5	-1.5	-1.3
Tibialis anterior weight	0.8	2.8	3.2	-1.3	-1.7	1.8	1.7	1.7	1.8
Time to tail flick, vehicle, before self-admin	2.0	2.0	2.9	0.6	1.4	-1.7	-1.5	-1.4	-1.7
Time to tail flick, vehicle, after self-admin	0.1	0.1	0.2	0.1	-0.5	0.5	0.4	0.3	0.4
Time to tail flick, test, before self-admin	0.1	0.1	0.4	-0.6	-0.4	0.2	0.3	0.3	0.3
Time to tail flick, test, after self-admin	0.1	0.1	0.8	-0.9	-0.0	-0.2	0.0	0.1	-0.2
Delta time to tail flick, vehicle, before/after SA	1.1	1.1	1.8	-0.4	-0.9	1.2	1.1	1.0	1.3
Delta time to tail flick, test, before/after SA	1.5	1.4	1.7	0.8	1.2	-1.3	-1.2	-1.2	-1.3
Tibia length	2.6	7.3	8.7	2.4	2.5	-2.8	-2.8	-2.8	-3.0
Ambulatory time before self-admin	0.4	0.4	0.4	0.6	0.6	-0.6	-0.6	-0.6	-0.7
Ambulatory time after self-admin	0.2	0.3	0.5	-0.7	-0.7	0.5	0.5	0.5	0.2
Bone: tissue strength	0.0	0.0	0.0	-0.1	-0.0	0.0	0.0	0.0	0.1
Total heroin consumption	0.8	1.0	1.9	-1.4	-1.2	0.8	0.9	0.9	0.6
Bone: trabecular number	1.2	1.8	2.8	-1.7	-1.4	1.2	1.3	1.3	1.2
Bone: trabecular spacing	2.0	2.6	2.9	1.7	1.6	-1.6	-1.6	-1.6	-1.5
Bone: trabecular thickness	0.3	0.4	0.6	0.1	0.6	-0.7	-0.6	-0.6	-0.7
Bone: trabecular tissue density	0.0	0.0	0.1	-0.3	0.1	-0.2	-0.2	-0.1	-0.3
Water consumed over 24 hours	1.3	1.6	1.9	-0.9	-1.3	1.4	1.3	1.3	1.3
Number of responses in last shaping day	1.0	1.0	1.7	0.5	-1.2	1.3	0.9	0.8	1.0