LOC102547047

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Eye	alternative TSS	XM_063270141.1	0.88	0.06	4.6e-04	-0.02	0.02	-0	0	7.6e-01	1.4e-01	3.7e-01	2.9e-01
2	RMTg	alternative TSS	XM_039087394.2	0.25	0.24	1.1e-03	0.12	0.05	0.08	0.05	4.8e-04	2.2e-02	4.1e-03	1.5e-02
3	RMTg	alternative TSS	XM_039087394.2	0.19	0.13	3.9e-04	0.1	-0	0.08	0.01	1.2e-03	4.0e-01	4.0e-03	1.9e-01
4	Adipose	gene expression	LOC102547047	0.05	0.04	3.2e-06	0.04	0.04	0.04	0.04	1.3e-05	5.8e-05	2.6e-05	6.5e-05
5	Adipose	isoform ratio	XR_005490436.2	0.02	0.01	8.0e-03	0.01	0	0.01	0.01	1.2e-02	7.5e-02	6.1e-02	4.9e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5
Bone: apparent density	1.3	2.2	2.9	1.3	1.7	1.7	-1.3	1.2
Area under the delay curve	0.1	0.2	0.4	-0.6	-0.1	0.0	0.2	-0.6
BMI with tail	18.9	65.2	74.8	8.1	8.2	8.6	-8.3	6.9
BMI without tail	1.9	5.8	8.5	2.9	2.3	2.5	-2.5	1.6
Body weight	0.9	3.9	6.3	-0.2	2.0	2.5	-2.2	2.1
Weight adjusted by age	0.1	0.2	0.5	-0.7	-0.3	-0.4	0.3	-0.1
Bone surface	0.5	0.8	1.4	0.0	1.0	1.2	-0.7	1.2
Bone volume	1.0	1.7	2.6	-0.1	1.5	1.6	-1.1	1.5
Breakpoint value in progressive ratio session	1.6	1.9	4.0	-0.0	-2.0	-1.6	1.0	-1.4
Number of licking bursts	0.8	1.2	1.9	0.2	-1.1	-1.0	1.4	-1.4
Context. condit. distance diff. score	0.9	1.1	1.5	0.6	1.1	1.1	-1.2	1.1
Locomotion velocity, session 1	0.1	0.1	0.2	0.3	-0.1	-0.1	0.4	-0.3
Locomotion distance, session 1	4.2	5.3	6.7	-1.6	-2.6	-2.3	2.5	-2.3
Locomotion velocity, session 2	1.3	1.5	4.0	-2.0	-1.2	-1.2	0.8	-0.6
Locomotion distance, session 2	5.5	7.7	9.7	-1.2	-3.1	-3.0	3.0	-3.1
Locomotion velocity, session 3	0.6	0.7	1.8	-0.3	0.5	0.6	-1.1	1.3
Locomotion distance, session 3	0.8	0.9	1.3	-0.6	-1.1	-1.2	0.7	-0.9
Stereotopy head waving bouts, day 3	3.8	4.5	6.3	1.3	1.9	2.2	-2.4	2.5
Stereotopy head waving duration, day 3	2.7	3.2	5.3	0.4	1.8	2.0	-1.9	2.3
Locomotion velocity, session 7	1.5	1.7	2.8	-1.7	-1.2	-1.1	1.2	-1.1
Locomotion distance, session 7	6.2	7.9	8.9	-2.5	-3.0	-2.6	3.0	-2.9
Stereotopy head waving bouts, day 7	0.3	0.4	0.6	0.6	0.3	0.5	-0.8	0.7
Stereotopy head waving duration, day 7	0.3	0.4	0.7	0.4	0.3	0.5	-0.8	0.8
Locomotion velocity, session 8	0.8	1.0	1.7	0.8	0.8	0.6	-1.3	1.3
Locomotion distance, session 8	0.4	0.5	0.8	-0.1	-0.9	-0.8	0.6	-0.8
Degree of sensitization distance	0.6	0.6	1.1	-1.0	-0.6	-0.4	0.9	-0.8
Degree of sensitization stereotypy	0.2	0.2	0.3	0.5	-0.6	-0.5	0.3	-0.4
Conditioned locomotion	1.1	1.3	3.1	-0.0	1.8	1.4	-0.6	1.0
Cocaine response after cond. corrected	4.8	5.8	7.4	2.7	2.6	2.5	-2.3	1.8
Cocaine response after cond. not corrected	2.9	3.4	5.0	2.2	1.9	2.0	-1.8	1.3
Cocaine response before conditioning	2.0	2.4	3.6	-1.2	-1.9	-1.7	1.3	-1.5
Saline control response	0.3	0.4	1.0	0.6	-0.1	0.0	0.9	-1.0
Bone: connectivity density	0.5	0.8	1.2	1.1	0.9	0.9	-0.7	0.7
Bone: cortical apparent density	4.6	6.3	7.8	-2.8	-2.7	-2.6	2.3	-2.0
Bone: cortical area	0.4	0.6	1.2	-0.1	1.0	1.1	-0.5	0.8
Bone: cortical porosity	0.1	0.1	0.3	0.0	0.5	0.5	-0.2	0.4
Bone: cortical porosity	0.2	0.2	0.6	0.1	0.6	0.8	-0.2	0.3
Bone: cortical thickness	0.1	0.2	0.4	-0.7	0.5	0.4	-0.1	0.5
Bone: cortical thickness	0.2	0.2	0.5	0.1	-0.6	-0.7	0.5	-0.2
Bone: cortical tissue density	5.2	7.0	8.4	-2.9	-2.9	-2.7	2.5	-2.2
Condit. Reinf. active minus inactive responses	1.0	1.2	1.8	-0.1	-1.3	-1.3	1.3	-0.8
Condit. Reinf. active-inactive response ratio	0.3	0.3	1.3	1.1	0.1	-0.1	-0.1	0.5
Condit. Reinf. active responses	1.1	1.4	2.1	-0.1	-1.4	-1.4	1.3	-1.1
Condit. Reinf. inactive responses	1.1	1.3	2.8	-0.4	-1.2	-0.9	1.1	-1.7
Incentive salience index mean	1.7	2.1	3.3	0.0	-1.6	-1.8	1.7	-1.4
Condit. Reinf. lever presses	2.2	3.1	4.2	0.2	-1.9	-2.0	1.9	-2.0
Condit. Reinf. active minus inactive responses	0.4	0.5	1.1	0.9	-0.3	-0.2	0.7	-1.0
Condit. Reinf. active-inactive response ratio	1.4	1.7	5.7	2.4	-0.3	-0.3	0.7	-1.4
Condit. Reinf. active responses	0.1	0.2	0.4	0.1	-0.3	0.0	0.6	-0.6
Condit. Reinf. inactive responses	0.3	0.4	2.0	-1.4	-0.0	0.2	0.0	0.4
Condit. Reinf. lever presses	0.4	0.6	2.2	-1.5	-0.5	-0.4	0.6	-0.2
Condit. Reinf. lever reinforcers received	0.2	0.2	0.6	-0.1	-0.4	-0.1	0.7	-0.7
Conditioned reinforcement - actives	0.6	1.0	1.4	-0.5	-1.2	-0.7	1.2	-1.2
Conditioned reinforcement - inactives	0.1	0.1	0.3	-0.5	-0.1	0.1	0.5	-0.3
Conditioned locomotion	0.2	0.3	0.8	0.9	0.5	0.7	-0.2	-0.2
Patch foraging indifference point 0 sec	1.1	2.0	2.7	0.5	1.5	1.5	-1.7	1.6
Patch foraging indifference point AUC	0.1	0.2	0.5	-0.7	-0.0	-0.4	0.4	0.1
Delay disc. indifference point, 0s delay	0.5	0.6	1.6	-1.3	0.0	-0.1	0.7	-0.9
Delay disc. indifference point, 16s delay	1.0	1.1	1.6	0.8	1.2	1.2	-1.3	0.7
Delay disc. indifference point, 2s delay	0.9	1.0	3.5	-1.9	-0.0	-0.1	0.8	-0.8
Delay disc. indifference point, 24s delay	0.4	0.4	0.8	-0.1	-0.7	-0.6	0.5	-0.9
Delay disc. indifference point, 4s delay	2.2	2.3	5.5	-2.3	-1.2	-1.0	1.3	-1.3
Delay disc. indifference point, 8s delay	0.1	0.1	0.3	-0.1	-0.3	-0.1	0.1	-0.5
Indifference point function ln k	0.0	0.1	0.3	0.1	-0.3	-0.1	-0.1	-0.5
Indifference point function log k	0.0	0.1	0.3	0.1	-0.3	-0.1	-0.1	-0.5
Patch foraging total patch changes 0 sec	1.1	2.0	2.6	0.3	1.6	1.5	-1.6	1.6
Patch foraging total patch changes 12 sec	0.1	0.1	0.4	-0.6	0.3	0.1	0.2	0.0
Patch foraging total patch changes 18 sec	1.3	2.0	3.2	0.3	1.7	1.6	-1.2	1.8
Patch foraging total patch changes 24 sec	0.5	0.8	1.2	0.2	1.0	0.9	-0.9	1.1
Patch foraging total patch changes 6 sec	0.6	0.9	1.4	0.4	1.0	1.0	-1.0	1.2
Patch foraging time to switch 0 sec	0.0	0.1	0.2	-0.0	-0.2	-0.3	0.5	-0.2
Patch foraging water rate 0 sec	1.3	2.7	4.1	0.9	1.6	1.6	-2.0	1.8
Patch foraging water rate 12 sec	0.4	0.8	1.3	0.4	0.4	0.9	-1.1	1.1
Patch foraging water rate 18 sec	0.0	0.1	0.2	-0.4	-0.0	0.0	-0.2	-0.2
Patch foraging water rate 24 sec	1.1	1.5	2.3	0.7	1.2	1.3	-1.5	1.3
Patch foraging water rate 6 sec	0.5	0.7	3.2	1.8	0.0	0.2	-0.6	0.1
Seeking ratio, delayed vs. immediate footshock	2.3	2.7	4.1	-0.5	2.0	2.0	-1.3	2.0
Distance traveled before self-admin	1.0	1.3	1.8	0.7	-1.4	-1.1	1.3	-1.2
Distance traveled after self-admin	1.3	1.6	7.2	2.7	0.0	0.2	-0.3	0.7
Extensor digitorum longus weight	0.9	3.4	5.5	0.0	1.9	1.9	-2.0	2.4
Bone: elastic displacement	0.1	0.1	0.2	0.5	0.2	0.1	-0.4	0.2
Bone: elastic work	0.1	0.1	0.3	-0.6	0.1	0.2	0.1	0.1
Bone: endosteal estimation	0.1	0.1	0.2	-0.5	0.4	0.5	-0.2	0.3
Bone: endosteal perimeter	0.3	0.6	0.9	0.4	0.9	0.9	-0.7	0.8
Epididymis fat weight	0.2	0.5	1.7	1.3	0.4	0.9	-0.2	-0.1
Delta time in closed arm before/after self-admin	0.5	0.5	1.4	-1.2	0.4	0.5	-0.3	0.6
Delta time in open arm before/after self-admin	0.6	0.6	0.8	-0.6	-0.8	-0.9	0.7	-0.7
Diff in mean of infusions in LGA sessions	1.1	1.4	2.7	0.0	-1.6	-1.3	1.2	-1.1
Delay discount exponential model param	0.2	0.2	0.5	0.7	0.3	0.1	-0.4	0.7
Extinction: sum of active levers before priming	1.9	2.1	5.0	-2.2	-1.1	-0.9	1.2	-1.3
Active lever presses in extinction session 6	0.9	0.9	2.6	1.6	0.3	0.4	-1.0	1.0
Bone: final force	0.1	0.2	0.6	0.4	0.6	0.8	0.1	0.0
Bone: final moment	0.2	0.3	0.8	0.5	0.7	0.9	-0.1	0.2
Food consumed during 24 hour testing period	1.6	2.3	3.2	-0.7	-1.6	-1.8	1.6	-1.5
Glucose	1.5	2.3	4.0	-0.3	1.8	1.6	-1.3	2.0
Heart weight	0.7	1.1	2.3	0.7	0.9	1.5	-0.9	0.9
Delay discount hyperbolic model param	0.3	0.3	0.8	0.9	0.3	0.1	-0.4	0.7
Intermittent access intake day 1-15 change	0.1	0.1	0.5	0.7	-0.1	-0.1	0.2	-0.3
Intermittent access intake escalation	0.2	0.3	1.5	1.2	-0.1	-0.1	0.1	-0.3
Intermittent access intake escalation 2	0.8	1.0	3.6	1.9	0.6	0.5	-0.6	0.5
Intermitt. access day 1 inactive lever presses	0.0	0.1	0.6	0.8	-0.1	-0.1	-0.0	-0.3
Intermitt. access day 15 inactive lever presses	0.8	1.7	2.6	0.4	1.5	1.2	-1.6	1.4
Intermitt. access escalation Index	0.3	0.4	0.6	0.6	-0.7	-0.7	0.5	-0.6
Intermittent access day 1 total infusions	0.1	0.2	0.8	-0.9	-0.3	-0.2	0.0	-0.3
Intermittent access day 15 total infusions	0.1	0.1	0.1	0.1	-0.3	-0.3	0.3	-0.4
Intermittent access terminal intake (last 3 days)	0.0	0.0	0.0	-0.1	-0.1	0.1	0.1	-0.2
Intermittent access total infusions	0.1	0.1	0.6	-0.8	-0.0	0.2	0.0	-0.1
Intermittent access day 1 locomotion	0.5	0.6	1.5	-1.2	-0.6	-0.6	0.4	-0.8
Intermittent access day 15 total locomotion	0.4	0.7	1.5	-1.0	-0.6	-0.3	0.8	-1.2
Intermittent access total locomotion	0.4	0.5	1.2	-1.1	-0.3	-0.1	0.4	-0.9
Intermittent access standard deviation	0.4	0.8	1.3	0.8	1.0	1.1	-0.9	0.4
Left kidney weight	0.1	0.4	1.6	-1.3	0.0	0.3	0.0	0.5
Right kidney weight	0.3	1.2	1.8	-0.6	1.1	1.4	-0.9	1.3
Cocaine induced anxiety	0.1	0.1	0.2	-0.4	0.3	0.4	0.2	0.4
Post-drug Anxiety	1.2	1.3	3.0	-1.7	-0.9	-0.7	1.3	-0.6
Baseline Anxiety	1.3	1.5	1.8	-1.2	-1.4	-1.2	1.1	-1.3
Tail length	17.7	69.0	77.5	-8.7	-8.7	-8.8	8.0	-7.1
Length with tail	8.6	37.3	72.6	-8.5	-5.8	-5.6	5.6	-4.2
Length without tail	0.7	2.3	8.9	-3.0	0.6	1.0	-0.4	1.0
Times rat made contact with spout	1.0	1.1	1.6	-0.7	-1.0	-1.1	1.2	-1.2
Lifetime Intake	0.0	0.1	0.2	-0.5	0.1	0.2	-0.2	-0.0
Liver weight, left	0.1	0.2	1.2	1.1	0.1	-0.0	-0.1	-0.0
Liver weight, right	0.2	0.3	1.1	-1.1	-0.4	-0.2	0.3	0.1
Locomotor activity	0.7	1.1	5.2	2.3	0.2	0.5	-0.2	-0.3
Locomotor testing distance	1.2	2.2	8.3	2.9	0.9	1.2	-0.6	-0.0
Locomotor testing rearing	0.5	0.9	4.1	2.0	0.4	0.6	-0.2	-0.2
Locomotion in novel chamber	0.2	0.2	0.6	-0.4	-0.4	-0.2	0.8	-0.0
Locomotion in novel chamber post-restriction	0.7	1.2	3.0	0.1	1.5	1.7	-0.4	0.6
Fecal boli incidents, locomotor time 1	3.5	5.1	6.7	2.3	1.9	1.8	-2.6	2.6
Change in fecal boli incidents, locomotor task	2.2	2.2	2.9	-1.1	-1.7	-1.3	1.7	-1.4
Time >=10cm from walls, locomotor time 1	0.3	0.3	1.0	1.0	-0.1	-0.1	0.6	-0.2
Bouts of movement, locomotor time 1	0.5	0.6	1.7	-1.3	0.4	0.7	-0.6	0.2
Total resting periods, locomotor time 1	0.7	0.8	1.1	-0.9	0.7	1.0	-1.0	0.6
Rest time, locomotor task time 1	0.1	0.1	0.2	0.2	0.5	0.3	-0.3	0.2
Distance moved, locomotor task time 1	1.1	1.7	2.1	-0.4	-1.5	-1.4	1.4	-1.4
Vertical activity count, locomotor time 1	0.2	0.5	0.9	0.0	-0.9	-0.6	0.6	-0.9
Time >=10cm from walls, locomotor time 2	0.3	0.5	0.6	0.6	-0.7	-0.8	0.6	-0.7
Bouts of movement, locomotor time 2	0.2	0.3	1.2	-1.1	0.3	0.3	0.2	-0.3
Total resting periods, locomotor time 2	0.2	0.3	1.0	-1.0	0.3	0.3	0.3	-0.4
Rest time, locomotor task time 2	0.5	0.6	1.0	-0.0	-1.0	-1.0	0.6	-0.9
Distance moved, locomotor task time 2	0.2	0.2	0.8	-0.9	-0.4	-0.3	0.2	-0.1
Vertical activity count, locomotor time 2	0.2	0.2	0.9	-1.0	-0.2	-0.1	0.4	-0.1
Light reinforcement 1	0.4	1.1	5.0	2.2	0.2	0.5	-0.3	-0.1
Light reinforcement 2	0.3	0.4	0.5	0.7	-0.4	-0.7	0.7	-0.7
Bone: marrow area	0.1	0.1	0.2	-0.5	0.3	0.4	-0.1	0.3
Bone: maximum diameter	0.5	0.9	1.3	1.1	0.9	1.0	-0.9	0.9
Bone: maximum force	0.4	0.8	1.7	-0.4	1.1	1.3	-0.3	0.9
Bone: maximum moment	0.6	1.1	2.2	-0.2	1.2	1.5	-0.6	1.2
Mean time between licks in bursts	0.5	1.2	2.1	-1.0	1.3	1.4	-0.9	0.6
Mean num. licks in bursts	0.2	0.4	1.6	-1.3	0.2	0.1	-0.2	0.4
Cd content in liver	0.3	0.3	0.7	0.9	-0.0	0.0	0.5	-0.6
Co content in liver	0.1	0.1	0.4	0.6	-0.1	0.0	0.0	-0.1
Cu content in liver	8.0	9.5	13.0	-1.7	-3.3	-3.0	3.6	-3.4
Fe content in liver	1.4	1.7	3.3	-1.8	-0.9	-0.7	1.5	-1.3
K content in liver	3.8	3.7	13.4	-3.7	-1.2	-0.9	1.4	-1.0
Mg content in liver	8.4	8.6	15.2	-3.9	-2.6	-2.3	3.0	-2.5
Mn content in liver	4.2	4.7	6.2	-1.9	-2.3	-2.5	2.2	-1.8
Na content in liver	0.9	1.0	3.8	-2.0	-0.4	-0.3	0.6	-0.5
Rb content in liver	0.9	1.0	1.9	0.8	-1.4	-0.5	1.1	-1.1
Se content in liver	0.1	0.1	0.4	0.3	0.6	0.4	-0.2	-0.0
Sr content in liver	1.8	1.5	4.4	-2.1	-0.8	-1.3	0.8	-0.5
Zn content in liver	0.4	0.4	0.8	-0.5	-0.5	-0.3	0.9	-0.8
Bone: minimum diameter	0.2	0.4	1.6	-1.3	0.2	0.6	0.1	0.3
Time in familiar zone, hab. session 1	0.2	0.2	0.5	0.6	-0.2	-0.2	0.5	-0.7
Time in novel zone, hab. session 1	2.1	2.1	3.8	0.2	1.2	1.3	-1.8	1.9
Total zone transitions, hab. session 1	5.7	8.0	10.7	-0.8	-3.3	-3.0	3.1	-3.1
Total locomotion distance, hab. session 1	3.4	4.8	6.4	-0.6	-2.5	-2.2	2.4	-2.5
Locomotion velocity, hab. session 1	4.6	6.4	8.7	-1.0	-2.8	-2.5	2.9	-2.9
Time in familiar zone, hab. session 2	1.9	2.0	4.5	2.1	1.2	1.1	-1.3	1.2
Time in novel zone, hab. session 2	0.5	0.5	1.5	-1.2	-0.4	-0.3	0.6	-0.6
Total zone transitions, hab. session 2	3.9	4.9	6.5	-0.7	-2.5	-2.3	2.5	-2.5
Total locomotion distance, hab. session 2	1.0	1.3	2.0	-0.5	-1.3	-1.0	1.2	-1.4
Locomotion velocity, hab. session 2	1.2	1.6	2.1	-0.7	-1.4	-1.2	1.4	-1.4
Novel to familiar place preference ratio	0.2	0.3	0.6	0.8	-0.4	-0.4	0.4	-0.5
Novelty place preference	0.2	0.2	0.7	0.8	-0.3	-0.3	0.3	-0.4
Time in novel zone, NPP test	0.3	0.4	1.7	1.3	-0.2	-0.2	0.0	-0.2
Total zone transitions, NPP test	5.3	7.6	11.5	-0.9	-2.8	-2.9	3.1	-3.4
Total locomotion distance, NPP test	2.0	2.8	4.6	-0.8	-1.6	-1.5	2.0	-2.1
Locomotion velocity, NPP test	2.6	3.7	5.2	-1.4	-1.8	-1.8	2.2	-2.3
Intraocular pressure	0.9	1.3	2.1	-1.0	-1.1	-1.0	1.5	-1.2
Delta distance traveled before/after self-admin	1.5	1.6	2.3	1.1	1.3	1.3	-1.2	1.5
Delta ambulatory time before/after self-admin	1.3	1.6	2.1	1.1	1.2	1.2	-1.2	1.5
Parametrial fat weight	0.1	0.2	0.4	-0.1	0.4	0.6	-0.5	0.4
Pavlov. Cond. lever latency	1.4	1.7	2.5	-1.1	1.2	1.3	-1.3	1.6
Pavlov. Cond. magazine entry latency	0.4	0.5	2.2	1.5	-0.4	-0.4	0.2	-0.4
Pavlov. Cond. change in total contacts	3.1	3.3	4.3	0.4	-2.0	-2.0	2.0	-2.1
Pavlov. Cond. index score	1.1	1.4	1.9	1.4	-1.1	-1.1	1.1	-1.3
Pavlov. Cond. latency score	1.0	1.3	1.4	1.1	-1.1	-1.1	1.1	-1.2
Pavlov. Cond. lever contacts	2.5	3.0	4.4	0.5	-1.7	-1.9	2.0	-2.1
Pavlov. Cond. magazine entry number	0.7	0.9	1.2	-0.9	0.9	0.8	-0.9	1.1
Pavlov. Cond. intertrial magazine entries	1.7	2.0	3.4	-1.8	-1.2	-1.0	1.4	-1.4
Pavlov. Cond. lever-magazine prob. diff.	1.1	1.4	2.1	1.4	-1.0	-1.1	1.0	-1.2
Pavlov. Cond. response bias	1.1	1.4	2.0	1.2	-1.0	-1.1	1.1	-1.4
Pavlov. Cond. lever latency	1.5	2.1	3.7	0.6	-1.6	-1.4	1.5	-1.9
Pavlov. Cond. magazine entry latency	1.1	1.3	5.5	-2.3	-0.4	-0.7	0.6	-0.0
Pavlov. Cond. change in total contacts	0.5	0.9	1.5	-1.0	0.9	0.7	-0.8	1.2
Pavlov. Cond. index score	0.7	1.0	2.0	-1.4	0.8	0.6	-0.6	1.2
Pavlov. Cond. latency score	0.5	0.7	2.1	-1.5	0.5	0.3	-0.4	0.9
Pavlov. Cond. lever contacts	1.3	1.8	3.1	-0.4	1.5	1.3	-1.4	1.7
Pavlov. Cond. magazine entry number	1.4	1.7	7.8	2.8	-0.2	-0.1	0.1	-0.8
Pavlov. Cond. intertrial magazine entries	1.4	2.0	3.3	1.1	-1.7	-1.3	1.1	-1.8
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.1	2.4	-1.5	0.8	0.7	-0.7	1.3
Pavlov. Cond. response bias	1.2	1.7	2.8	-0.9	1.4	1.2	-1.2	1.7
Time in closed arm before self-admin	2.8	3.6	5.8	1.1	2.0	1.8	-1.9	2.4
Time in closed arm after self-admin	2.9	3.1	5.9	-0.3	2.0	1.8	-1.6	2.4
Time in open arm before self-admin	0.8	0.8	2.0	-0.7	-0.6	-0.5	1.0	-1.4
Time in open arm after self-admin	1.9	2.1	3.8	-0.6	-1.5	-1.5	1.4	-1.9
Bone: periosteal estimation	0.3	0.6	1.3	0.1	0.9	1.1	-0.5	0.7
Bone: periosteal perimeter	1.3	2.2	2.9	1.2	1.7	1.7	-1.3	1.5
Bone: post-yield work	0.8	1.1	2.1	-0.4	1.0	1.2	-1.0	1.5
Progressive ratio test 1 active lever presses	1.1	1.4	2.1	-0.6	-1.2	-1.2	1.3	-1.5
Progressive ratio test 1 breakpoint	0.9	1.1	1.6	-0.5	-1.1	-1.0	1.1	-1.3
Progressive ratio test 1 inactive lever presses	0.7	0.9	3.4	1.8	0.7	0.5	-0.7	0.3
Progressive ratio test 2 active lever presses	0.7	0.8	1.4	-0.5	-0.9	-0.3	1.2	-1.1
Progressive ratio test 2 breakpoint	0.6	0.7	1.3	-0.3	-0.9	-0.3	1.1	-1.1
Progressive ratio test 2 inactive lever presses	0.0	0.0	0.2	-0.1	0.1	0.4	0.2	-0.1
Incentive Sensitization - Responses	0.2	0.3	0.5	-0.3	-0.2	0.5	0.7	-0.7
Incentive Sensitization - Breakpoint	0.1	0.2	0.4	-0.0	-0.0	0.6	0.5	-0.5
Sum of active levers in priming session hrs 5-6	3.2	3.0	4.7	-1.1	-2.2	-2.1	1.5	-1.6
Progressive ratio	0.1	0.2	0.4	0.2	0.6	0.4	0.2	-0.4
Food seeking constrained by brief footshock	0.5	0.7	3.0	1.7	-0.1	-0.1	-0.3	0.5
Seeking ratio, punishment vs. effort	0.3	0.5	1.4	-0.2	-1.2	-1.0	0.3	-0.1
Retroperitoneal fat weight	0.3	1.4	2.6	0.9	1.4	1.6	-1.0	0.7
Reaction time number correct	0.7	1.3	2.0	-0.3	1.3	1.4	-1.1	1.2
Reaction time mean minus median	1.2	3.0	6.1	-2.5	-1.5	-1.6	1.6	-1.2
Reaction time mean minus median AUC	1.5	3.8	6.3	-2.5	-1.8	-1.8	1.9	-1.6
Reaction time num false alarms	0.9	1.3	2.0	1.0	-1.4	-1.2	0.9	-1.2
Reaction time num false alarms AUC	0.9	1.5	2.4	0.8	-1.5	-1.3	1.0	-1.3
Reaction time trials correct on left	0.7	1.3	2.0	-0.3	1.3	1.4	-1.1	1.2
Reaction time trials on left	0.6	1.2	1.9	-0.3	1.2	1.4	-1.0	1.2
Reaction time mean	1.2	1.9	4.9	-2.2	-1.1	-1.2	1.0	-0.7
Reaction time mean AUC	1.3	2.1	5.1	-2.2	-1.2	-1.4	1.1	-0.9
Median of all reaction times	0.6	0.9	2.5	-1.6	-0.8	-0.9	0.6	-0.4
Reaction time omissions	1.1	1.6	2.3	-0.8	-1.5	-1.4	1.2	-1.2
Reaction time false alarm rate	1.6	2.2	3.3	0.9	-1.8	-1.6	1.3	-1.6
Reaction time premature initiation rate	0.2	0.2	0.4	-0.1	-0.5	-0.6	0.6	-0.6
Reaction time premature initiations	0.0	0.0	0.2	-0.5	0.1	0.0	0.0	0.1
Std. dev. reaction times	1.6	2.9	6.6	-2.6	-1.5	-1.6	1.4	-1.0
Reaction time trials completed	0.6	1.2	1.9	-0.3	1.2	1.4	-1.0	1.2
Reaction time trials AUC	0.6	1.2	1.9	-0.2	1.3	1.4	-1.1	1.2
Run reversals in cocaine runway, females	0.1	0.1	0.2	0.1	-0.4	-0.2	0.0	0.4
Run reversals in cocaine runway, males	0.8	0.8	1.8	0.6	1.2	1.3	-0.5	-0.2
Latency to leave start box in cocaine runway	4.9	5.6	9.1	-1.0	2.7	2.5	-2.1	3.0
Latency to leave start box in cocaine runway, F	6.3	7.3	11.0	-0.2	3.3	2.9	-2.7	3.1
Latency to leave start box in cocaine runway, M	0.7	0.7	1.8	-1.3	0.3	0.4	-0.0	1.1
Std. dev. time between licks in bursts	0.7	0.9	1.3	0.4	1.2	1.1	-1.0	0.8
Total sessions with >9 infusions	0.2	0.3	1.2	-1.1	0.2	-0.1	-0.2	-0.0
Short access day 1 total inactive lever presses	0.2	0.3	0.5	-0.7	-0.5	-0.3	0.7	-0.3
Short access day 10 total inactive lever presses	0.5	1.2	2.4	0.9	1.2	1.6	-1.0	0.7
Short access day 1 total infusions	0.2	0.2	0.7	-0.9	0.4	0.2	-0.3	0.4
Short access day 10 total infusions	0.1	0.2	0.8	-0.9	0.1	0.1	-0.0	-0.2
Short access total infusions	0.3	0.3	0.7	-0.8	0.6	0.4	-0.6	0.5
Short access day 1 locomotion	0.2	0.3	0.6	-0.5	0.8	0.6	-0.5	0.4
Short access day 10 total locomotion	0.0	0.1	0.2	-0.3	0.1	0.1	-0.1	-0.4
Short access total locomotion	0.2	0.2	0.4	-0.6	0.5	0.4	-0.3	-0.0
One hour access (0.3 mA shock)	0.4	0.5	0.7	-0.1	-0.8	-0.8	0.7	-0.8
Compulsive drug intake	1.7	2.0	3.8	-0.2	-2.0	-1.9	1.1	-1.1
One hour access (shock baseline)	0.4	0.6	1.1	0.6	1.0	1.1	-0.6	0.4
Social response proportion	1.8	2.0	3.6	-0.6	-1.6	-1.9	1.5	-1.2
Social responses	0.6	0.8	3.7	1.9	-0.0	-0.3	-0.2	0.0
Social time	1.8	2.4	11.8	3.4	0.4	0.2	-0.4	-0.3
Soleus weight	1.4	4.2	5.7	0.6	2.1	2.3	-2.3	2.4
Bone: stiffness	0.2	0.3	0.9	-0.9	0.2	0.5	0.6	0.1
Tibialis anterior weight	0.1	0.4	1.7	1.3	-0.4	-0.4	0.0	-0.0
Time to tail flick, vehicle, before self-admin	2.6	2.7	3.3	-1.1	-1.8	-1.8	1.7	-1.8
Time to tail flick, vehicle, after self-admin	1.1	1.4	2.3	0.2	1.4	1.4	-1.0	1.5
Time to tail flick, test, before self-admin	0.6	0.7	1.9	-0.3	0.7	0.5	-0.9	1.4
Time to tail flick, test, after self-admin	0.9	0.9	1.3	-0.7	1.0	1.0	-0.9	1.2
Delta time to tail flick, vehicle, before/after SA	6.0	5.7	7.9	1.9	2.5	2.4	-2.2	2.8
Delta time to tail flick, test, before/after SA	0.3	0.3	0.8	-0.3	-0.5	-0.4	0.5	-0.9
Tibia length	0.6	1.7	2.8	-1.1	1.4	1.7	-1.0	1.3
Ambulatory time before self-admin	0.5	0.8	1.0	0.8	-1.0	-0.7	1.0	-1.0
Ambulatory time after self-admin	0.6	0.7	3.2	1.8	0.0	0.4	-0.3	0.5
Bone: tissue strength	1.2	1.2	1.7	-1.3	1.1	1.3	-0.8	0.9
Total heroin consumption	0.9	1.1	1.9	1.4	-1.3	-1.2	0.3	-0.6
Bone: trabecular number	0.2	0.4	0.8	0.9	0.7	0.7	-0.3	0.3
Bone: trabecular spacing	0.5	0.6	3.0	1.7	0.1	-0.1	-0.2	-0.4
Bone: trabecular thickness	3.8	4.8	6.9	-0.9	2.5	2.3	-2.2	2.6
Bone: trabecular tissue density	0.3	0.5	2.1	-1.5	-0.1	-0.1	0.2	-0.3
Water consumed over 24 hours	0.1	0.1	0.2	-0.2	-0.3	-0.5	0.5	-0.3
Number of responses in last shaping day	0.9	0.9	1.4	-0.4	1.2	1.2	-0.8	1.0