Hub : Genes

LOC102546674

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression LOC102546674 0.03 0.02 3.3e-03 0.03 0.02 0.03 0.03 1.4e-03 4.1e-03 1.4e-03 1.9e-03
2 Liver gene expression LOC102546674 0.1 0.06 2.9e-07 0.04 0.06 0.05 0.05 6.1e-05 5.7e-07 2.0e-06 7.8e-06
3 Adipose isoform ratio XM_063270139.1 0.03 0.02 2.7e-03 0.01 0.01 0.01 0.01 1.4e-02 8.6e-03 4.2e-02 1.7e-02
4 pVTA gene expression LOC102546674 0.06 0.04 1.9e-04 0.04 0.05 0.04 0.04 6.7e-04 5.5e-05 2.4e-04 3.4e-04
5 IC isoform ratio XM_063270139.1 0.05 0.04 8.1e-03 0.04 0.04 0.04 0.05 7.3e-03 6.6e-03 1.1e-02 3.3e-03
6 Adipose gene expression LOC102546674 0.12 0.08 2.5e-11 0.1 0.09 0.1 0.1 3.3e-11 3.4e-10 1.1e-10 5.0e-11
7 PL gene expression LOC102546674 0.11 0.06 8.2e-10 0.1 0.1 0.09 0.1 7.3e-11 1.4e-10 4.8e-10 4.1e-11
8 PL isoform ratio XM_063270139.1 0.05 0.03 1.3e-04 0.04 0.03 0.03 0.04 1.7e-05 4.6e-04 1.8e-04 6.2e-05
9 NAcc gene expression LOC102546674 0.09 0.04 9.8e-14 0.1 0.1 0.1 0.1 5.0e-15 2.3e-14 2.5e-14 4.4e-15

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density0.10.21.1-1.00.5-0.60.4-0.2-0.10.20.30.3
Area under the delay curve0.00.00.00.20.20.00.0-0.10.00.10.10.0
BMI with tail5.218.240.5-5.76.4-4.55.3-2.6-3.53.02.72.7
BMI without tail0.21.05.0-1.12.2-0.71.40.0-0.70.30.10.1
Body weight1.46.010.7-2.13.3-2.22.8-2.2-2.32.32.32.3
Weight adjusted by age0.10.20.40.3-0.30.5-0.40.6-0.1-0.4-0.6-0.6
Bone surface0.20.40.9-1.00.9-0.60.7-0.6-0.30.50.60.6
Bone volume0.71.52.1-1.41.2-1.21.1-1.2-0.81.11.31.3
Breakpoint value in progressive ratio session1.12.12.51.5-1.01.6-1.51.31.5-1.6-1.4-1.4
Number of licking bursts0.82.53.41.4-1.91.5-1.61.51.5-1.6-1.4-1.5
Context. condit. distance diff. score0.30.41.1-1.00.5-0.80.7-0.4-0.50.50.50.5
Locomotion velocity, session 10.40.50.90.5-0.10.6-0.30.91.0-0.7-0.7-0.8
Locomotion distance, session 12.63.35.12.3-1.52.1-1.72.02.0-1.7-1.4-1.4
Locomotion velocity, session 20.10.10.40.40.30.10.2-0.1-0.10.40.60.6
Locomotion distance, session 24.46.19.33.1-2.12.8-2.32.82.7-2.4-1.9-1.9
Locomotion velocity, session 31.92.23.4-1.41.8-1.41.7-1.5-1.41.41.31.4
Locomotion distance, session 30.30.30.60.8-0.40.6-0.50.50.6-0.5-0.4-0.4
Stereotopy head waving bouts, day 33.74.45.6-2.41.9-2.32.2-2.2-1.61.92.12.1
Stereotopy head waving duration, day 33.34.15.1-2.31.7-2.22.0-2.2-1.82.02.02.0
Locomotion velocity, session 70.10.10.70.80.20.40.1-0.20.2-0.00.30.3
Locomotion distance, session 72.32.95.82.4-2.11.9-1.91.41.6-1.4-1.2-1.2
Stereotopy head waving bouts, day 70.30.40.6-0.60.8-0.50.6-0.8-0.30.40.60.6
Stereotopy head waving duration, day 70.60.71.5-0.70.9-0.80.8-1.2-0.70.70.70.7
Locomotion velocity, session 80.70.92.7-1.01.6-0.71.3-0.5-0.50.60.80.8
Locomotion distance, session 80.60.91.90.9-0.61.1-0.81.41.2-1.0-0.7-0.7
Degree of sensitization distance0.10.10.30.5-0.50.2-0.30.0-0.00.10.00.1
Degree of sensitization stereotypy0.40.40.70.6-0.40.7-0.60.50.8-0.8-0.5-0.5
Conditioned locomotion0.60.71.2-1.10.7-1.00.8-0.8-0.90.70.70.6
Cocaine response after cond. corrected0.71.12.5-1.61.3-1.31.2-1.0-0.90.70.60.6
Cocaine response after cond. not corrected0.30.41.3-1.10.6-0.90.6-0.5-0.80.40.30.2
Cocaine response before conditioning1.21.42.81.3-1.71.1-1.41.40.8-0.8-0.9-0.9
Saline control response1.52.12.61.3-1.41.4-1.41.61.4-1.5-1.6-1.6
Bone: connectivity density0.10.10.2-0.40.00.1-0.30.40.3-0.4-0.5-0.5
Bone: cortical apparent density0.60.92.41.6-1.61.0-1.10.70.6-0.6-0.3-0.3
Bone: cortical area0.30.60.9-0.70.9-0.70.8-0.7-0.40.60.90.9
Bone: cortical porosity0.20.20.3-0.30.6-0.40.5-0.6-0.40.40.60.6
Bone: cortical porosity0.20.20.4-0.30.5-0.40.5-0.4-0.40.50.60.6
Bone: cortical thickness0.40.61.1-0.40.6-0.70.9-0.9-0.50.71.01.0
Bone: cortical thickness0.20.30.70.4-0.50.5-0.40.40.8-0.7-0.4-0.4
Bone: cortical tissue density0.71.22.91.7-1.71.2-1.20.80.7-0.7-0.4-0.4
Condit. Reinf. active minus inactive responses0.80.91.51.0-0.81.2-1.01.21.0-1.0-0.7-0.8
Condit. Reinf. active-inactive response ratio0.10.10.2-0.2-0.20.2-0.20.40.3-0.4-0.2-0.2
Condit. Reinf. active responses0.91.22.01.2-0.71.3-1.01.41.0-1.0-1.0-0.9
Condit. Reinf. inactive responses1.21.62.41.5-0.91.3-1.21.41.2-1.1-1.3-1.3
Incentive salience index mean1.92.43.81.6-1.21.8-1.51.91.7-1.5-1.3-1.3
Condit. Reinf. lever presses3.04.65.92.3-1.82.3-2.12.42.4-2.1-1.8-1.8
Condit. Reinf. active minus inactive responses1.32.02.31.2-1.41.3-1.51.51.4-1.5-1.4-1.4
Condit. Reinf. active-inactive response ratio3.45.57.71.7-2.12.1-2.32.42.2-2.5-2.7-2.8
Condit. Reinf. active responses0.50.71.20.7-0.80.8-0.81.10.8-0.7-0.7-0.7
Condit. Reinf. inactive responses0.50.71.3-0.50.7-0.70.8-0.5-0.61.01.11.2
Condit. Reinf. lever presses0.10.10.50.20.70.10.40.1-0.00.30.40.4
Condit. Reinf. lever reinforcers received0.50.71.20.8-0.80.9-0.81.10.9-0.7-0.7-0.7
Conditioned reinforcement - actives0.31.01.81.3-0.61.2-0.81.11.2-1.0-0.9-0.9
Conditioned reinforcement - inactives0.00.10.30.5-0.30.2-0.20.10.1-0.3-0.3-0.3
Conditioned locomotion0.20.30.70.5-0.20.4-0.30.60.8-0.6-0.6-0.6
Patch foraging indifference point 0 sec0.71.92.8-1.51.7-1.41.5-1.3-1.41.21.21.2
Patch foraging indifference point AUC0.10.30.80.00.9-0.10.7-0.5-0.10.30.70.7
Delay disc. indifference point, 0s delay0.10.10.30.5-0.10.3-0.10.20.1-0.2-0.3-0.3
Delay disc. indifference point, 16s delay0.81.11.8-1.01.4-1.11.2-0.9-0.80.91.11.0
Delay disc. indifference point, 2s delay0.10.10.40.2-0.5-0.1-0.2-0.6-0.20.30.20.2
Delay disc. indifference point, 24s delay0.20.30.70.9-0.00.6-0.30.60.4-0.5-0.4-0.5
Delay disc. indifference point, 4s delay0.10.10.40.7-0.20.2-0.2-0.2-0.00.20.20.2
Delay disc. indifference point, 8s delay0.00.10.10.3-0.20.1-0.20.20.2-0.2-0.3-0.3
Indifference point function ln k0.10.20.30.4-0.50.2-0.40.50.0-0.2-0.6-0.6
Indifference point function log k0.10.20.30.4-0.50.2-0.40.50.0-0.2-0.6-0.6
Patch foraging total patch changes 0 sec0.72.23.2-1.51.8-1.51.6-1.5-1.51.31.31.3
Patch foraging total patch changes 12 sec0.00.00.10.10.30.10.2-0.00.10.10.10.1
Patch foraging total patch changes 18 sec1.12.64.3-1.62.1-1.51.8-1.6-1.31.41.51.5
Patch foraging total patch changes 24 sec0.20.50.9-0.91.0-0.70.8-0.7-0.50.60.70.6
Patch foraging total patch changes 6 sec0.81.43.5-1.11.9-1.01.5-1.3-0.80.80.91.0
Patch foraging time to switch 0 sec0.10.60.80.4-0.90.6-0.70.40.9-0.8-0.9-0.9
Patch foraging water rate 0 sec0.82.94.3-1.82.1-1.71.9-1.2-1.51.71.71.6
Patch foraging water rate 12 sec0.31.12.4-1.11.6-1.01.2-0.8-1.11.10.80.7
Patch foraging water rate 18 sec0.00.00.10.1-0.2-0.1-0.10.3-0.10.2-0.1-0.1
Patch foraging water rate 24 sec0.71.01.6-1.11.3-1.11.2-0.7-1.01.00.80.8
Patch foraging water rate 6 sec0.20.31.00.20.10.5-0.31.00.6-0.6-0.7-0.7
Seeking ratio, delayed vs. immediate footshock1.72.44.1-2.01.5-1.51.5-1.5-1.81.61.31.3
Distance traveled before self-admin1.94.14.82.0-1.62.1-1.92.02.2-2.1-2.1-2.1
Distance traveled after self-admin0.81.32.3-0.1-0.81.0-1.01.41.0-1.3-1.5-1.5
Extensor digitorum longus weight1.35.310.1-2.33.2-2.12.6-2.2-2.22.12.02.0
Bone: elastic displacement0.00.00.1-0.10.30.10.20.20.1-0.10.10.1
Bone: elastic work0.00.00.10.00.30.10.20.00.1-0.00.30.3
Bone: endosteal estimation0.00.10.2-0.30.4-0.10.2-0.1-0.20.30.20.2
Bone: endosteal perimeter0.10.20.7-0.60.8-0.40.4-0.3-0.20.40.50.5
Epididymis fat weight0.10.30.80.3-0.40.4-0.50.20.5-0.6-0.9-0.9
Delta time in closed arm before/after self-admin1.41.31.7-0.81.0-0.90.9-1.3-1.31.31.21.2
Delta time in open arm before/after self-admin0.30.30.50.6-0.60.5-0.50.50.6-0.7-0.6-0.6
Diff in mean of infusions in LGA sessions1.32.32.91.4-1.01.7-1.31.71.5-1.7-1.7-1.6
Delay discount exponential model param0.00.00.1-0.3-0.0-0.10.1-0.0-0.10.00.00.0
Extinction: sum of active levers before priming0.20.31.31.1-0.20.7-0.50.10.6-0.3-0.2-0.2
Active lever presses in extinction session 60.10.10.2-0.30.5-0.10.2-0.00.3-0.2-0.2-0.2
Bone: final force0.10.20.60.2-0.40.2-0.30.20.8-0.5-0.2-0.2
Bone: final moment0.00.10.40.0-0.30.0-0.10.10.6-0.4-0.0-0.1
Food consumed during 24 hour testing period0.71.42.01.4-0.81.4-1.11.01.0-1.2-1.4-1.3
Glucose2.33.64.9-2.20.8-2.11.5-1.9-2.02.02.02.0
Heart weight0.20.30.8-0.90.4-0.50.3-0.5-0.80.60.10.1
Delay discount hyperbolic model param0.00.00.1-0.2-0.1-0.0-0.00.20.0-0.1-0.1-0.1
Intermittent access intake day 1-15 change0.00.20.40.20.50.5-0.10.30.5-0.7-0.4-0.4
Intermittent access intake escalation0.10.40.80.30.30.7-0.30.70.7-0.9-0.8-0.8
Intermittent access intake escalation 20.20.30.7-0.40.50.4-0.10.60.6-0.8-0.6-0.6
Intermitt. access day 1 inactive lever presses0.00.20.50.0-0.30.3-0.20.30.4-0.7-0.7-0.7
Intermitt. access day 15 inactive lever presses0.63.24.4-1.62.1-1.82.0-1.8-1.71.61.71.7
Intermitt. access escalation Index0.20.50.90.4-0.60.6-0.61.00.4-0.7-0.9-0.9
Intermittent access day 1 total infusions0.00.10.30.1-0.3-0.40.1-0.6-0.20.40.50.5
Intermittent access day 15 total infusions0.10.10.20.50.10.4-0.20.20.5-0.4-0.4-0.4
Intermittent access terminal intake (last 3 days)0.00.00.10.10.40.10.1-0.10.2-0.10.00.0
Intermittent access total infusions0.10.10.20.10.2-0.30.2-0.5-0.20.40.50.5
Intermittent access day 1 locomotion0.00.10.30.6-0.4-0.0-0.1-0.3-0.20.20.20.2
Intermittent access day 15 total locomotion0.00.10.70.8-0.00.3-0.2-0.10.4-0.30.10.1
Intermittent access total locomotion0.10.10.30.6-0.00.1-0.0-0.20.2-0.00.30.3
Intermittent access standard deviation0.10.41.5-0.51.2-0.50.8-0.6-0.00.30.60.5
Left kidney weight0.10.51.3-0.70.6-0.60.6-0.4-1.10.90.60.6
Right kidney weight0.21.52.0-1.41.2-1.21.1-1.0-1.41.41.11.1
Cocaine induced anxiety0.00.10.70.10.80.10.50.10.00.1-0.2-0.2
Post-drug Anxiety0.20.20.90.90.30.60.00.10.7-0.2-0.2-0.2
Baseline Anxiety0.20.30.90.9-0.90.3-0.6-0.10.7-0.10.20.1
Tail length2.815.134.55.9-4.94.5-4.62.43.3-2.8-2.4-2.4
Length with tail0.52.18.12.9-2.21.5-1.7-0.40.60.10.40.5
Length without tail1.05.27.3-1.81.6-2.21.9-2.7-2.12.62.72.7
Times rat made contact with spout0.40.40.91.0-0.60.6-0.60.60.3-0.4-0.7-0.7
Lifetime Intake0.10.10.2-0.00.1-0.30.2-0.4-0.20.40.50.4
Liver weight, left0.20.30.80.40.10.4-0.20.50.9-0.6-0.7-0.7
Liver weight, right0.10.10.3-0.20.5-0.30.4-0.5-0.40.40.30.3
Locomotor activity0.50.82.40.5-0.40.7-0.51.61.0-0.9-0.9-0.9
Locomotor testing distance0.40.91.90.4-0.40.6-0.51.41.2-1.1-1.2-1.2
Locomotor testing rearing0.41.62.80.6-0.71.0-0.81.61.2-1.5-1.7-1.6
Locomotion in novel chamber0.50.60.90.4-0.60.9-0.90.90.6-0.9-0.9-0.9
Locomotion in novel chamber post-restriction0.00.10.3-0.50.2-0.40.2-0.3-0.50.30.20.2
Fecal boli incidents, locomotor time 11.33.35.9-2.42.1-1.92.1-1.5-1.41.61.51.5
Change in fecal boli incidents, locomotor task1.51.62.51.3-1.61.3-1.41.20.8-1.0-1.3-1.3
Time >=10cm from walls, locomotor time 11.82.23.70.8-1.31.4-1.41.91.4-1.5-1.7-1.7
Bouts of movement, locomotor time 11.11.52.1-0.81.2-1.21.5-1.1-1.01.31.31.3
Total resting periods, locomotor time 11.82.02.8-1.11.5-1.51.7-1.3-1.21.51.51.5
Rest time, locomotor task time 10.20.40.5-0.50.5-0.70.7-0.4-0.60.70.70.7
Distance moved, locomotor task time 11.13.13.81.8-2.01.7-2.01.51.7-1.8-1.7-1.7
Vertical activity count, locomotor time 10.21.01.81.2-0.41.0-0.70.81.3-1.1-1.1-1.1
Time >=10cm from walls, locomotor time 20.41.22.00.7-1.40.9-1.11.30.8-1.0-1.1-1.2
Bouts of movement, locomotor time 20.00.10.20.20.20.20.00.40.2-0.3-0.3-0.3
Total resting periods, locomotor time 20.00.20.40.40.10.4-0.10.60.4-0.5-0.5-0.5
Rest time, locomotor task time 20.10.30.70.6-0.80.4-0.70.40.2-0.3-0.3-0.3
Distance moved, locomotor task time 20.10.10.3-0.0-0.2-0.30.1-0.5-0.50.30.40.4
Vertical activity count, locomotor time 20.00.10.20.00.5-0.00.4-0.3-0.20.20.10.1
Light reinforcement 10.31.22.40.5-0.40.8-0.71.31.1-1.2-1.6-1.5
Light reinforcement 20.61.41.90.9-1.01.1-1.11.41.2-1.2-1.4-1.3
Bone: marrow area0.00.00.1-0.20.4-0.00.10.0-0.10.20.20.1
Bone: maximum diameter0.00.10.3-0.50.6-0.20.3-0.0-0.00.00.10.0
Bone: maximum force0.30.60.9-0.80.7-0.80.8-0.9-0.30.60.90.8
Bone: maximum moment0.50.91.2-1.00.9-1.01.0-1.1-0.60.81.11.0
Mean time between licks in bursts0.42.22.6-0.91.6-1.41.6-1.5-1.41.51.61.6
Mean num. licks in bursts0.51.32.0-0.71.3-1.01.1-1.2-1.31.41.11.1
Cd content in liver0.80.91.50.8-0.90.9-1.10.71.0-1.2-0.8-0.8
Co content in liver0.10.10.10.2-0.30.3-0.30.30.2-0.4-0.3-0.3
Cu content in liver7.18.411.43.4-2.73.3-2.92.62.9-2.9-2.6-2.6
Fe content in liver0.81.01.41.1-1.21.0-1.10.71.2-0.8-0.7-0.8
K content in liver0.70.61.40.4-0.1-0.30.3-1.0-0.81.01.21.2
Mg content in liver1.31.54.02.0-1.81.4-1.50.50.7-0.7-0.4-0.5
Mn content in liver1.21.33.21.8-0.91.6-1.21.11.0-0.9-0.7-0.7
Na content in liver0.10.10.30.2-0.2-0.10.0-0.3-0.10.50.50.6
Rb content in liver2.52.94.51.3-1.51.6-1.61.41.7-2.0-2.1-2.1
Se content in liver0.00.10.30.1-0.60.0-0.4-0.00.0-0.1-0.1-0.1
Sr content in liver0.20.20.40.30.2-0.10.1-0.6-0.60.60.60.6
Zn content in liver0.40.41.10.6-1.10.7-1.00.20.5-0.6-0.4-0.4
Bone: minimum diameter0.30.61.1-0.50.1-0.60.3-0.8-0.90.91.01.0
Time in familiar zone, hab. session 11.41.52.70.8-1.60.9-1.40.91.1-1.3-1.5-1.5
Time in novel zone, hab. session 14.14.66.0-2.02.5-2.02.3-1.8-2.02.12.32.3
Total zone transitions, hab. session 14.96.810.43.2-2.13.0-2.52.82.8-2.5-2.1-2.1
Total locomotion distance, hab. session 12.94.16.82.6-1.62.4-2.02.32.4-1.9-1.2-1.2
Locomotion velocity, hab. session 13.85.48.93.0-2.02.7-2.32.52.7-2.2-1.5-1.5
Time in familiar zone, hab. session 20.20.20.8-0.90.8-0.50.5-0.2-0.30.1-0.1-0.1
Time in novel zone, hab. session 20.10.10.30.4-0.60.2-0.30.00.2-0.00.20.2
Total zone transitions, hab. session 24.15.27.22.7-2.02.5-2.22.52.7-2.1-1.8-1.8
Total locomotion distance, hab. session 20.91.12.11.4-0.91.2-1.01.31.4-0.9-0.4-0.3
Locomotion velocity, hab. session 20.81.02.01.4-0.91.2-1.01.21.3-0.8-0.3-0.3
Novel to familiar place preference ratio0.60.81.20.7-0.81.0-1.01.01.1-0.9-0.8-0.8
Novelty place preference0.50.71.10.6-0.70.8-0.90.91.1-0.9-0.7-0.7
Time in novel zone, NPP test0.50.71.10.4-0.80.7-0.90.91.1-0.9-0.8-0.8
Total zone transitions, NPP test5.27.711.63.4-2.73.0-2.73.03.1-2.6-2.1-2.1
Total locomotion distance, NPP test1.82.54.42.1-1.51.8-1.51.91.9-1.4-0.7-0.7
Locomotion velocity, NPP test1.52.24.62.2-1.31.8-1.41.71.7-1.2-0.6-0.6
Intraocular pressure0.50.91.51.2-0.41.0-0.70.50.9-0.9-1.2-1.1
Delta distance traveled before/after self-admin1.01.13.0-1.70.9-1.00.9-0.7-1.10.80.80.8
Delta ambulatory time before/after self-admin0.71.12.9-1.70.8-1.10.9-0.8-1.20.90.90.9
Parametrial fat weight0.10.20.5-0.6-0.4-0.6-0.0-0.5-0.70.50.50.4
Pavlov. Cond. lever latency3.54.46.3-1.91.9-2.11.9-2.5-2.22.12.12.1
Pavlov. Cond. magazine entry latency0.91.22.20.8-0.71.1-0.91.51.1-1.2-1.2-1.2
Pavlov. Cond. change in total contacts5.76.17.12.3-2.32.6-2.52.72.5-2.5-2.5-2.5
Pavlov. Cond. index score3.13.96.21.6-1.62.0-1.72.52.1-2.1-2.0-2.0
Pavlov. Cond. latency score2.73.55.51.5-1.61.9-1.62.32.0-1.9-1.9-1.9
Pavlov. Cond. lever contacts4.55.47.32.3-2.22.4-2.22.72.5-2.3-2.1-2.1
Pavlov. Cond. magazine entry number1.82.33.5-1.31.2-1.61.4-1.9-1.51.61.51.5
Pavlov. Cond. intertrial magazine entries0.40.51.31.1-0.90.8-0.90.30.7-0.4-0.5-0.5
Pavlov. Cond. lever-magazine prob. diff.3.23.96.21.6-1.62.0-1.72.52.0-2.1-2.1-2.1
Pavlov. Cond. response bias2.93.65.31.7-1.52.0-1.72.31.9-2.0-1.9-1.9
Pavlov. Cond. lever latency2.63.64.61.8-2.21.8-2.11.61.5-1.8-2.1-2.1
Pavlov. Cond. magazine entry latency0.91.32.3-0.31.1-0.80.9-1.2-1.11.31.51.5
Pavlov. Cond. change in total contacts0.92.23.7-1.21.9-1.31.7-1.2-1.21.41.61.6
Pavlov. Cond. index score1.82.94.0-1.21.9-1.51.7-1.6-1.41.72.02.0
Pavlov. Cond. latency score1.42.33.4-1.01.6-1.31.5-1.4-1.31.61.81.9
Pavlov. Cond. lever contacts2.02.94.2-1.62.1-1.61.9-1.4-1.31.61.91.8
Pavlov. Cond. magazine entry number2.93.75.91.2-1.71.6-1.72.01.8-2.2-2.4-2.4
Pavlov. Cond. intertrial magazine entries2.14.55.81.9-1.92.0-1.92.41.9-2.2-2.4-2.4
Pavlov. Cond. lever-magazine prob. diff.2.13.24.5-1.32.1-1.51.9-1.7-1.41.82.12.1
Pavlov. Cond. response bias2.43.44.3-1.62.0-1.82.0-1.7-1.41.82.12.1
Time in closed arm before self-admin1.52.74.1-2.01.8-1.71.9-1.3-1.41.51.41.5
Time in closed arm after self-admin4.85.56.6-2.42.4-2.22.4-2.1-2.62.52.32.3
Time in open arm before self-admin0.80.92.21.1-1.51.0-1.40.60.6-0.8-0.6-0.7
Time in open arm after self-admin1.71.92.71.7-1.51.4-1.41.21.3-1.4-1.3-1.2
Bone: periosteal estimation0.10.20.3-0.50.6-0.40.4-0.3-0.10.40.50.5
Bone: periosteal perimeter0.40.71.4-1.21.2-0.80.9-0.5-0.60.70.70.7
Bone: post-yield work1.11.92.6-1.41.6-1.31.5-1.4-1.31.31.31.2
Progressive ratio test 1 active lever presses0.61.11.71.3-1.31.1-1.21.00.8-0.9-0.9-0.9
Progressive ratio test 1 breakpoint0.50.91.41.2-1.20.9-1.10.90.6-0.8-0.8-0.8
Progressive ratio test 1 inactive lever presses0.00.10.1-0.3-0.1-0.10.10.3-0.0-0.4-0.4-0.4
Progressive ratio test 2 active lever presses0.81.21.61.2-0.71.2-0.91.21.1-1.1-1.0-1.1
Progressive ratio test 2 breakpoint1.01.31.51.2-0.71.2-1.01.21.1-1.2-1.1-1.1
Progressive ratio test 2 inactive lever presses0.00.10.20.20.40.20.20.40.2-0.2-0.4-0.4
Incentive Sensitization - Responses0.30.81.20.9-0.11.0-0.51.11.0-1.0-1.0-1.0
Incentive Sensitization - Breakpoint0.30.71.10.8-0.10.9-0.51.10.9-1.0-1.0-1.0
Sum of active levers in priming session hrs 5-61.71.62.61.6-1.61.3-1.60.91.4-1.1-0.9-0.9
Progressive ratio0.10.40.70.5-0.40.7-0.70.70.6-0.8-0.7-0.7
Food seeking constrained by brief footshock0.20.30.7-0.1-0.60.3-0.50.40.8-0.8-0.5-0.5
Seeking ratio, punishment vs. effort0.00.10.30.1-0.6-0.1-0.2-0.20.30.10.10.1
Retroperitoneal fat weight0.00.10.3-0.50.5-0.40.5-0.3-0.10.10.20.2
Reaction time number correct0.41.52.6-1.41.0-1.41.2-1.0-1.61.40.90.9
Reaction time mean minus median0.10.31.31.1-0.40.8-0.50.20.3-0.3-0.3-0.3
Reaction time mean minus median AUC0.11.02.31.5-0.91.2-1.00.60.6-0.8-0.9-0.9
Reaction time num false alarms0.71.21.81.2-0.81.2-1.01.31.2-1.1-1.0-1.0
Reaction time num false alarms AUC0.51.11.61.3-0.81.2-0.91.31.2-1.1-0.9-0.9
Reaction time trials correct on left0.41.52.6-1.41.0-1.41.2-1.0-1.61.40.90.9
Reaction time trials on left0.41.42.5-1.41.0-1.41.1-1.0-1.61.30.90.9
Reaction time mean0.10.10.40.60.10.40.0-0.1-0.10.20.50.5
Reaction time mean AUC0.00.10.60.7-0.00.5-0.10.0-0.00.10.30.3
Median of all reaction times0.10.10.30.40.20.20.1-0.0-0.10.20.50.5
Reaction time omissions0.40.71.81.3-0.41.2-0.70.80.5-0.8-0.8-0.7
Reaction time false alarm rate1.62.23.31.7-1.11.6-1.31.71.8-1.6-1.2-1.2
Reaction time premature initiation rate0.10.20.50.7-0.40.5-0.50.40.4-0.3-0.4-0.4
Reaction time premature initiations0.00.10.2-0.10.1-0.30.1-0.3-0.40.50.20.2
Std. dev. reaction times0.00.10.80.9-0.20.5-0.2-0.1-0.10.10.20.3
Reaction time trials completed0.41.42.5-1.41.0-1.41.1-1.0-1.61.30.90.9
Reaction time trials AUC0.41.42.5-1.40.9-1.41.1-1.0-1.61.30.80.8
Run reversals in cocaine runway, females0.20.20.5-0.50.4-0.30.5-0.5-0.70.40.50.5
Run reversals in cocaine runway, males0.00.00.20.20.1-0.00.00.00.5-0.2-0.1-0.1
Latency to leave start box in cocaine runway4.86.68.4-2.92.7-2.42.4-2.6-2.72.52.52.4
Latency to leave start box in cocaine runway, F7.08.811.4-3.42.6-3.02.7-2.9-3.23.02.82.8
Latency to leave start box in cocaine runway, M0.30.31.4-0.51.2-0.10.6-0.4-0.30.30.40.4
Std. dev. time between licks in bursts0.40.71.5-0.71.2-0.91.2-0.9-0.40.60.70.7
Total sessions with >9 infusions0.60.71.1-0.20.4-0.80.7-1.0-0.71.01.11.1
Short access day 1 total inactive lever presses0.10.10.20.50.10.5-0.30.40.3-0.3-0.5-0.4
Short access day 10 total inactive lever presses0.10.62.3-1.01.5-0.51.0-0.4-0.90.40.20.2
Short access day 1 total infusions0.30.61.1-0.40.5-0.90.8-0.9-0.61.00.90.9
Short access day 10 total infusions0.20.30.5-0.2-0.0-0.50.3-0.5-0.70.60.70.7
Short access total infusions0.71.01.4-0.60.6-1.10.9-1.1-1.01.21.21.2
Short access day 1 locomotion0.50.81.5-0.51.2-0.81.0-1.1-0.50.90.90.9
Short access day 10 total locomotion0.00.00.10.1-0.3-0.20.0-0.3-0.10.10.20.2
Short access total locomotion0.40.60.9-0.30.4-0.80.7-0.9-0.60.81.00.9
One hour access (0.3 mA shock)0.91.12.21.2-0.51.1-0.81.11.5-1.0-0.9-0.9
Compulsive drug intake1.42.12.61.4-1.61.4-1.61.31.5-1.2-1.5-1.5
One hour access (shock baseline)0.10.20.8-0.20.9-0.20.6-0.1-0.00.10.30.3
Social response proportion1.31.72.11.3-1.41.3-1.31.31.4-1.1-1.2-1.2
Social responses0.60.71.50.4-0.60.8-0.71.20.9-1.0-0.9-0.9
Social time1.62.53.80.9-1.01.3-1.22.01.7-1.9-1.8-1.8
Soleus weight1.75.26.1-2.52.1-2.32.3-2.0-2.02.32.52.4
Bone: stiffness0.00.00.2-0.1-0.3-0.1-0.1-0.40.10.10.20.1
Tibialis anterior weight0.20.61.10.40.20.7-0.40.81.1-0.9-0.9-1.0
Time to tail flick, vehicle, before self-admin1.62.02.81.7-1.51.4-1.41.21.6-1.2-1.4-1.3
Time to tail flick, vehicle, after self-admin0.30.61.4-1.20.8-0.80.8-0.7-0.70.60.70.7
Time to tail flick, test, before self-admin1.21.31.9-0.90.8-1.21.1-1.2-1.01.41.31.3
Time to tail flick, test, after self-admin2.12.22.8-1.60.8-1.61.2-1.5-1.71.61.61.6
Delta time to tail flick, vehicle, before/after SA2.02.24.8-2.21.5-1.61.5-1.1-1.41.21.31.2
Delta time to tail flick, test, before/after SA0.20.30.80.3-0.90.4-0.70.40.4-0.5-0.4-0.4
Tibia length1.02.94.2-1.51.2-1.81.7-1.7-1.41.82.02.0
Ambulatory time before self-admin1.03.23.81.7-1.21.9-1.61.91.9-1.8-1.9-1.9
Ambulatory time after self-admin0.30.50.8-0.2-0.60.6-0.70.90.6-0.8-0.9-0.9
Bone: tissue strength2.02.12.8-1.11.0-1.51.3-1.7-1.31.51.71.7
Total heroin consumption2.12.53.31.1-1.61.4-1.81.61.7-1.8-1.5-1.5
Bone: trabecular number0.20.30.6-0.0-0.50.4-0.70.60.8-0.6-0.5-0.5
Bone: trabecular spacing0.40.51.00.60.10.7-0.20.80.8-0.9-1.0-1.0
Bone: trabecular thickness6.38.710.8-2.92.6-2.92.8-2.9-2.73.13.33.3
Bone: trabecular tissue density0.71.21.9-0.10.7-0.90.9-1.2-1.31.21.41.4
Water consumed over 24 hours0.00.00.10.20.10.2-0.10.10.1-0.2-0.3-0.3
Number of responses in last shaping day1.62.13.5-0.81.9-1.31.6-1.7-0.91.41.51.5