Hub : Genes

LOC102546453

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA intron excision ratio chr13_106197010_106206431 0.11 0.06 1.4e-05 0.07 0.07 0.07 0.06 3.2e-06 4.5e-06 2.7e-06 1.1e-05
2 pVTA mRNA stability LOC102546453 0.11 0.06 9.5e-06 0.05 0.07 0.07 0.07 4.5e-05 3.2e-06 1.8e-06 3.3e-06
3 pVTA isoform ratio XR_010057150.1 0.06 0.04 5.6e-04 0 0.03 0.01 0 2.9e-01 3.9e-03 5.2e-02 1.2e-01
4 pVTA isoform ratio XR_010057151.1 0.06 0.04 1.1e-03 -0 0.02 0.01 0 3.8e-01 1.2e-02 9.2e-02 2.8e-01
5 NAcc gene expression LOC102546453 0.16 0.07 0.0e+00 0.1 0.14 0.14 0.14 3.8e-14 1.9e-20 1.1e-20 4.5e-20
6 PL gene expression LOC102546453 0.33 0.14 0.0e+00 0.21 0.21 0.22 0.22 4.9e-22 1.3e-22 2.0e-23 4.1e-23
7 Brain gene expression LOC102546453 0.28 0.1 0.0e+00 0.23 0.25 0.24 0.24 1.3e-21 1.3e-23 5.5e-22 4.2e-22
8 LHb gene expression LOC102546453 0.65 0.13 2.8e-07 0.21 0.31 0.28 0.29 9.8e-06 4.8e-08 1.9e-07 1.1e-07
9 pVTA gene expression LOC102546453 0.63 0.12 0.0e+00 0.42 0.44 0.45 0.45 7.5e-37 4.7e-39 3.3e-40 5.0e-40
10 pVTA intron excision ratio chr13_106197010_106207322 0.06 0.04 1.2e-03 0.02 0.03 0.01 0.01 6.1e-03 1.7e-03 8.4e-02 3.7e-02
11 BLA mRNA stability LOC102546453 0.11 0.07 3.3e-03 0.03 0.01 0.01 0.03 6.3e-03 7.0e-02 8.9e-02 8.5e-03
12 IC gene expression LOC102546453 0.24 0.11 5.6e-06 0.13 0.13 0.13 0.13 3.1e-06 6.3e-06 5.2e-06 3.5e-06
13 PL mRNA stability LOC102546453 0.13 0.08 4.5e-09 0.1 0.08 0.07 0.1 5.6e-11 1.1e-08 8.4e-08 1.2e-10
14 LHb mRNA stability LOC102546453 0.44 0.16 8.7e-06 0.24 0.17 0.17 0.19 1.9e-06 8.6e-05 6.1e-05 2.7e-05
15 Brain mRNA stability LOC102546453 0.19 0.08 5.9e-15 0.19 0.18 0.18 0.18 2.6e-17 2.8e-16 1.8e-16 1.2e-16
16 BLA gene expression LOC102546453 0.31 0.11 8.4e-15 0.25 0.24 0.25 0.25 1.5e-13 4.7e-13 2.1e-13 1.6e-13
17 NAcc mRNA stability LOC102546453 0.07 0.04 6.4e-09 0.06 0.06 0.06 0.06 1.5e-09 4.0e-09 9.5e-09 5.7e-09
18 Adipose mRNA stability LOC102546453 0.49 0.11 0.0e+00 0.39 0.4 0.39 0.39 1.6e-45 1.0e-46 4.0e-46 9.6e-46
19 Adipose gene expression LOC102546453 0.44 0.12 0.0e+00 0.26 0.35 0.34 0.34 1.8e-28 5.4e-40 2.5e-38 2.6e-39

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.20.41.4-0.9-0.4-1.11.2-0.4-0.5-0.2-0.1-0.41.2-0.1-0.1-0.1-0.1-0.10.0-0.01.00.6
Area under the delay curve0.40.51.6-0.5-0.90.0-0.1-0.7-0.8-0.5-1.3-1.0-0.2-0.8-0.8-0.8-0.6-0.8-0.9-0.8-0.2-0.6
BMI with tail0.10.20.5-0.40.0-0.70.7-0.10.3-0.10.40.20.70.40.30.30.40.60.30.30.60.5
BMI without tail0.72.27.1-2.7-1.8-2.42.4-1.8-1.4-1.6-0.6-1.42.0-0.8-0.8-0.8-0.9-0.8-0.9-1.01.00.1
Body weight2.39.919.5-4.2-3.9-4.03.9-4.4-3.5-3.1-1.4-3.52.7-2.8-2.9-2.9-2.8-2.6-3.0-3.0-0.3-1.9
Weight adjusted by age0.71.02.7-1.2-1.2-1.31.3-1.6-1.1-0.5-0.2-1.11.1-0.9-0.9-0.9-0.9-1.0-1.1-0.7-0.1-0.7
Bone surface0.20.41.6-0.9-0.4-1.21.3-0.5-0.40.10.5-0.31.2-0.0-0.0-0.0-0.1-0.10.0-0.00.50.2
Bone volume0.40.72.1-1.4-0.9-1.51.4-0.8-0.9-0.7-0.3-0.71.3-0.4-0.4-0.4-0.5-0.5-0.4-0.40.80.3
Breakpoint value in progressive ratio session1.21.54.4-1.9-1.3-2.12.1-1.4-1.2-1.0-0.0-1.01.6-1.0-0.9-0.9-1.0-0.9-0.8-0.70.3-0.3
Number of licking bursts0.30.41.0-0.60.3-0.80.80.00.40.70.60.31.00.70.70.70.90.50.50.50.90.7
Context. condit. distance diff. score0.30.41.5-0.9-0.8-0.90.8-1.2-0.6-0.2-0.2-0.70.8-0.4-0.5-0.5-0.4-0.5-0.5-0.50.1-0.3
Locomotion velocity, session 10.80.93.0-0.70.7-1.01.10.60.80.91.70.91.20.90.90.90.70.91.01.00.70.8
Locomotion distance, session 10.40.51.9-0.70.1-1.31.3-0.30.30.61.20.21.40.50.50.50.40.40.40.40.50.4
Locomotion velocity, session 20.30.31.3-1.1-0.6-0.90.9-0.5-0.4-0.3-0.3-0.40.8-0.2-0.2-0.2-0.3-0.3-0.3-0.20.70.3
Locomotion distance, session 20.10.10.3-0.5-0.2-0.60.5-0.2-0.2-0.10.1-0.10.4-0.1-0.1-0.1-0.3-0.2-0.1-0.10.10.0
Locomotion velocity, session 31.61.83.6-1.9-1.7-1.71.6-1.5-1.6-1.6-0.8-1.41.1-1.3-1.3-1.3-1.4-1.2-1.2-1.10.2-0.5
Locomotion distance, session 31.01.13.0-0.4-1.20.2-0.2-0.8-1.2-1.5-1.7-1.1-0.6-1.2-1.1-1.1-1.3-1.2-1.1-1.1-0.3-0.7
Stereotopy head waving bouts, day 32.22.57.6-0.21.5-1.01.11.11.62.02.81.61.51.81.81.81.71.71.71.70.91.2
Stereotopy head waving duration, day 32.73.26.7-1.11.2-1.81.91.01.51.82.61.52.31.91.91.91.81.81.91.81.91.9
Locomotion velocity, session 70.60.72.50.8-0.01.0-1.10.1-0.1-1.0-0.6-0.4-1.5-0.5-0.5-0.5-0.5-0.6-0.7-0.7-1.6-1.2
Locomotion distance, session 70.70.93.51.10.01.6-1.70.3-0.0-0.8-1.2-0.3-1.9-0.5-0.5-0.5-0.5-0.6-0.7-0.7-1.3-0.9
Stereotopy head waving bouts, day 71.21.45.7-2.1-0.5-2.42.4-0.6-0.30.31.2-0.22.40.30.30.30.30.30.30.31.20.7
Stereotopy head waving duration, day 71.61.97.6-2.3-0.3-2.62.6-0.5-0.10.61.30.12.70.60.60.60.60.70.70.61.81.2
Locomotion velocity, session 80.50.62.1-1.0-0.1-1.21.2-0.10.00.60.60.31.50.40.40.40.30.50.50.61.31.0
Locomotion distance, session 80.30.41.0-0.9-0.6-1.01.0-1.0-0.50.00.2-0.50.9-0.4-0.4-0.4-0.4-0.5-0.4-0.30.0-0.3
Degree of sensitization distance0.80.91.60.91.30.7-0.71.11.21.01.01.0-0.41.11.01.01.11.00.90.9-0.00.5
Degree of sensitization stereotypy0.80.83.3-1.8-0.7-1.71.7-0.6-0.7-0.40.1-0.51.6-0.2-0.2-0.2-0.2-0.0-0.0-0.11.20.6
Conditioned locomotion1.51.72.70.91.50.5-0.41.61.51.51.31.60.11.51.41.41.31.61.61.60.91.4
Cocaine response after cond. corrected0.40.40.90.40.80.3-0.30.50.90.90.70.7-0.10.90.90.90.90.80.60.60.10.3
Cocaine response after cond. not corrected0.60.81.6-0.10.8-0.30.30.40.91.31.10.80.71.11.11.11.11.10.90.90.70.8
Cocaine response before conditioning0.40.41.7-1.1-0.5-1.21.2-0.5-0.6-0.00.0-0.31.3-0.3-0.2-0.2-0.2-0.10.10.11.10.6
Saline control response0.81.13.1-1.5-1.2-0.90.9-0.7-1.2-1.2-1.7-0.90.9-0.7-0.7-0.7-0.7-0.7-0.5-0.51.80.9
Bone: connectivity density0.50.83.4-1.2-0.1-1.61.6-0.3-0.20.60.6-0.01.80.40.40.40.40.40.50.41.51.0
Bone: cortical apparent density0.40.61.91.0-0.11.2-1.2-0.2-0.1-0.4-0.6-0.3-1.4-0.5-0.5-0.5-0.5-0.5-0.6-0.6-1.4-1.1
Bone: cortical area1.62.46.0-2.4-2.0-1.91.8-1.8-1.8-1.5-1.1-1.71.3-1.4-1.4-1.4-1.4-1.5-1.4-1.40.4-0.5
Bone: cortical porosity0.40.41.8-0.50.2-0.50.5-0.00.20.70.00.30.90.50.50.50.70.60.50.51.41.1
Bone: cortical porosity0.40.41.6-0.30.3-0.30.30.10.40.70.00.40.70.60.60.60.80.70.60.61.31.1
Bone: cortical thickness0.50.83.4-1.8-1.0-1.51.5-0.9-0.8-0.6-0.2-0.71.3-0.4-0.4-0.4-0.3-0.5-0.4-0.40.80.2
Bone: cortical thickness1.41.66.4-2.5-1.1-2.42.4-1.1-0.9-0.50.2-0.62.3-0.2-0.2-0.2-0.4-0.2-0.1-0.11.60.8
Bone: cortical tissue density0.50.62.11.0-0.11.2-1.3-0.2-0.1-0.4-0.7-0.3-1.5-0.4-0.4-0.4-0.5-0.5-0.6-0.6-1.4-1.1
Condit. Reinf. active minus inactive responses0.30.40.70.2-0.50.3-0.3-0.5-0.6-0.7-0.6-0.6-0.6-0.6-0.7-0.7-0.7-0.7-0.6-0.7-0.8-0.8
Condit. Reinf. active-inactive response ratio0.30.31.11.10.51.0-0.90.50.50.50.00.4-0.80.30.30.30.40.30.30.3-0.3-0.0
Condit. Reinf. active responses1.31.62.7-0.5-1.5-0.40.3-1.4-1.4-1.6-1.1-1.4-0.2-1.4-1.4-1.4-1.6-1.5-1.4-1.4-1.0-1.3
Condit. Reinf. inactive responses1.41.72.9-1.3-1.7-1.21.1-1.7-1.5-1.5-0.9-1.50.6-1.3-1.3-1.3-1.6-1.5-1.4-1.3-0.4-0.9
Incentive salience index mean1.11.32.1-0.2-1.3-0.0-0.1-1.2-1.3-1.4-1.2-1.3-0.5-1.3-1.4-1.4-1.5-1.3-1.3-1.3-1.0-1.2
Condit. Reinf. lever presses1.92.74.7-1.2-2.0-0.90.8-2.0-1.9-2.2-1.7-1.90.2-1.7-1.8-1.8-2.0-1.8-1.9-1.8-0.6-1.2
Condit. Reinf. active minus inactive responses0.10.21.4-0.2-0.30.2-0.20.3-0.4-0.6-1.2-0.3-0.1-0.2-0.2-0.2-0.2-0.2-0.1-0.10.90.6
Condit. Reinf. active-inactive response ratio0.40.41.20.80.71.1-1.01.10.60.4-0.20.6-0.80.50.50.50.50.50.60.60.20.5
Condit. Reinf. active responses0.50.73.0-0.5-1.0-0.00.0-0.4-1.1-1.2-1.7-1.0-0.1-1.0-1.0-1.0-0.8-1.0-0.8-0.80.50.0
Condit. Reinf. inactive responses2.22.84.5-1.3-2.0-1.21.1-2.0-2.1-2.0-1.8-2.00.5-1.9-1.9-1.9-1.8-1.9-1.8-1.8-0.2-1.0
Condit. Reinf. lever presses1.01.43.5-1.0-1.5-0.40.3-1.1-1.5-1.5-1.9-1.5-0.0-1.3-1.3-1.3-1.1-1.4-1.3-1.30.0-0.6
Condit. Reinf. lever reinforcers received0.50.82.7-0.5-1.0-0.0-0.0-0.5-1.1-1.2-1.6-1.0-0.2-1.0-1.0-1.0-0.9-1.0-0.9-0.80.2-0.2
Conditioned reinforcement - actives0.30.62.4-1.5-0.5-1.41.4-0.9-0.40.00.3-0.41.4-0.1-0.0-0.00.3-0.2-0.20.20.80.3
Conditioned reinforcement - inactives0.60.93.6-1.6-0.8-1.91.9-1.3-0.7-0.10.7-0.71.7-0.3-0.3-0.3-0.4-0.3-0.4-0.40.2-0.3
Conditioned locomotion1.21.56.2-2.3-0.8-2.52.5-1.2-0.6-0.00.7-0.42.4-0.1-0.1-0.10.2-0.20.00.31.30.6
Patch foraging indifference point 0 sec0.91.76.4-2.5-0.9-2.42.5-0.8-0.7-0.00.0-0.62.50.1-0.0-0.00.1-0.10.10.02.11.2
Patch foraging indifference point AUC0.50.72.91.40.51.7-1.71.00.20.1-0.60.2-1.7-0.1-0.1-0.1-0.1-0.00.0-0.1-0.9-0.5
Delay disc. indifference point, 0s delay0.20.20.8-0.90.0-0.90.9-0.40.20.10.5-0.10.90.40.40.40.40.4-0.00.00.30.1
Delay disc. indifference point, 16s delay1.01.03.0-1.3-1.4-0.50.4-1.0-1.4-0.7-1.7-1.30.4-1.1-1.1-1.1-0.9-1.1-1.0-0.80.5-0.2
Delay disc. indifference point, 2s delay0.00.00.3-0.0-0.20.0-0.0-0.1-0.20.0-0.5-0.20.1-0.1-0.1-0.1-0.20.0-0.1-0.10.50.3
Delay disc. indifference point, 24s delay1.41.65.8-0.8-1.50.3-0.3-1.1-1.4-1.1-2.4-1.6-0.5-1.5-1.4-1.4-1.1-1.5-1.5-1.3-0.1-0.8
Delay disc. indifference point, 4s delay1.11.12.30.4-0.90.4-0.4-0.9-1.1-0.8-1.0-1.1-0.7-1.3-1.2-1.2-1.1-1.2-1.3-1.3-1.4-1.5
Delay disc. indifference point, 8s delay0.10.10.3-0.20.20.3-0.30.50.30.2-0.40.1-0.10.40.40.40.40.40.10.20.40.4
Indifference point function ln k0.81.44.6-1.60.2-1.91.9-0.40.50.91.50.42.10.90.90.91.00.90.70.81.41.1
Indifference point function log k0.81.44.6-1.60.2-1.91.9-0.40.50.91.50.42.10.90.90.91.00.90.70.81.41.1
Patch foraging total patch changes 0 sec0.91.76.0-2.4-0.9-2.42.4-0.9-0.8-0.1-0.1-0.62.5-0.0-0.1-0.10.0-0.20.0-0.12.01.1
Patch foraging total patch changes 12 sec0.60.82.1-1.5-1.0-1.21.1-0.8-1.1-0.7-0.7-1.10.9-0.7-0.7-0.7-0.7-0.9-0.7-0.90.4-0.2
Patch foraging total patch changes 18 sec0.30.51.1-0.0-0.7-0.0-0.0-0.4-1.1-0.5-0.6-0.8-0.2-0.9-0.9-0.9-0.8-1.0-0.8-0.8-0.7-0.9
Patch foraging total patch changes 24 sec0.61.12.1-0.9-1.3-0.40.4-0.8-1.4-1.3-1.4-1.10.1-1.2-1.2-1.2-1.3-1.2-0.9-1.00.0-0.4
Patch foraging total patch changes 6 sec0.81.22.6-1.6-1.3-1.01.0-1.0-1.5-1.2-1.5-1.30.7-0.9-1.0-1.0-0.7-1.1-0.8-1.10.6-0.1
Patch foraging time to switch 0 sec0.40.84.61.0-0.20.3-0.3-0.7-0.6-0.10.6-0.5-0.6-0.8-0.8-0.8-0.9-0.8-0.7-0.8-2.1-1.8
Patch foraging water rate 0 sec0.81.68.8-1.9-0.0-1.21.30.40.40.3-0.40.41.71.00.90.91.10.80.80.83.02.3
Patch foraging water rate 12 sec0.20.52.6-1.20.1-0.20.20.10.5-0.1-0.80.20.40.60.60.60.70.50.30.41.61.3
Patch foraging water rate 18 sec0.60.93.9-2.0-0.4-1.41.4-0.40.1-0.3-0.10.11.50.40.40.40.40.50.40.41.91.4
Patch foraging water rate 24 sec0.30.41.5-0.90.1-0.70.80.10.30.30.40.50.90.40.40.40.40.40.60.51.21.1
Patch foraging water rate 6 sec0.40.63.2-1.6-0.4-0.80.8-0.30.1-0.1-0.60.01.00.30.30.30.30.20.20.21.81.3
Seeking ratio, delayed vs. immediate footshock0.81.03.4-0.4-1.30.4-0.5-0.6-1.1-1.4-1.9-0.9-0.7-1.0-1.0-1.0-1.4-1.0-0.7-0.90.1-0.3
Distance traveled before self-admin1.31.77.1-1.7-0.1-2.32.4-0.5-0.10.81.20.22.70.50.50.50.60.60.70.62.01.4
Distance traveled after self-admin1.21.54.5-0.80.6-1.81.80.00.81.02.10.92.01.01.01.01.01.11.01.11.11.0
Extensor digitorum longus weight0.31.22.30.3-0.90.2-0.3-0.7-1.1-1.4-0.8-0.9-0.8-1.4-1.5-1.5-1.5-1.2-1.0-1.1-1.4-1.3
Bone: elastic displacement1.72.04.00.21.4-0.50.50.71.61.92.01.51.01.71.71.71.91.51.61.61.01.3
Bone: elastic work1.21.53.9-0.11.2-0.70.80.51.31.62.01.21.21.41.41.41.61.31.31.30.71.0
Bone: endosteal estimation0.00.00.1-0.2-0.1-0.20.2-0.1-0.1-0.20.0-0.20.0-0.2-0.2-0.2-0.2-0.3-0.2-0.3-0.3-0.3
Bone: endosteal perimeter0.71.52.3-0.8-1.4-0.30.2-1.1-1.4-1.4-1.3-1.5-0.2-1.5-1.5-1.5-1.5-1.5-1.5-1.4-0.9-1.3
Epididymis fat weight0.41.45.4-1.8-0.3-2.22.2-0.5-0.10.31.0-0.02.30.60.60.60.60.70.40.51.71.1
Delta time in closed arm before/after self-admin0.20.20.50.70.60.5-0.50.60.60.20.60.5-0.50.40.40.40.20.30.40.4-0.5-0.1
Delta time in open arm before/after self-admin3.43.36.7-1.5-2.2-0.70.6-1.9-2.2-2.4-2.6-2.3-0.0-2.0-2.0-2.0-1.9-2.0-2.1-2.1-0.3-1.2
Diff in mean of infusions in LGA sessions0.60.72.2-1.5-0.8-1.51.5-0.7-0.8-0.5-0.2-0.61.4-0.5-0.5-0.5-0.4-0.4-0.3-0.31.10.5
Delay discount exponential model param0.60.72.10.51.0-0.10.20.70.90.61.51.10.30.90.90.90.80.91.10.90.30.7
Extinction: sum of active levers before priming3.53.88.1-2.8-2.4-2.62.6-2.4-2.3-2.2-0.8-1.91.8-1.9-1.9-1.9-1.9-1.9-1.5-1.50.2-0.7
Active lever presses in extinction session 62.72.78.6-2.3-1.7-2.92.9-1.9-1.7-1.00.6-1.32.3-1.3-1.3-1.3-1.3-1.3-1.2-0.8-0.0-0.8
Bone: final force0.40.62.6-1.5-0.4-1.61.6-0.7-0.3-0.10.7-0.41.4-0.0-0.0-0.00.1-0.0-0.2-0.20.3-0.0
Bone: final moment0.40.72.4-1.5-0.8-1.61.5-0.9-0.6-0.50.4-0.71.2-0.4-0.4-0.4-0.3-0.4-0.5-0.50.1-0.3
Food consumed during 24 hour testing period0.30.41.2-1.00.0-1.11.1-0.30.20.40.70.01.10.50.50.50.60.30.20.20.50.4
Glucose1.01.63.31.11.50.9-0.81.21.61.81.31.4-0.31.61.51.51.51.31.31.20.10.6
Heart weight1.21.83.1-1.6-1.7-1.21.2-1.4-1.7-1.6-1.2-1.50.7-1.5-1.5-1.5-1.4-1.4-1.3-1.10.0-0.7
Delay discount hyperbolic model param0.70.72.10.51.10.00.00.81.00.71.51.20.11.00.90.90.81.01.11.00.20.7
Intermittent access intake day 1-15 change0.81.73.51.41.61.0-0.91.51.51.91.81.5-0.61.31.21.21.21.31.31.3-0.60.3
Intermittent access intake escalation1.02.14.21.31.80.8-0.71.61.72.12.01.7-0.31.51.51.51.51.51.51.6-0.10.7
Intermittent access intake escalation 21.01.21.80.21.20.2-0.11.21.31.31.31.20.21.31.31.31.31.41.11.20.50.8
Intermitt. access day 1 inactive lever presses0.00.10.40.10.10.1-0.10.10.1-0.40.1-0.1-0.30.0-0.0-0.00.20.0-0.2-0.3-0.6-0.5
Intermitt. access day 15 inactive lever presses0.81.72.7-0.9-1.5-0.30.2-1.3-1.6-1.3-1.3-1.5-0.3-1.6-1.6-1.6-1.6-1.5-1.5-1.5-0.9-1.3
Intermitt. access escalation Index0.70.92.50.5-0.51.0-1.0-0.4-0.4-0.7-1.1-0.9-1.3-0.8-0.7-0.7-0.7-1.0-1.1-1.2-1.6-1.5
Intermittent access day 1 total infusions0.81.33.7-1.9-1.3-1.91.9-1.7-1.0-0.9-0.1-1.01.6-0.8-0.8-0.8-0.8-0.7-0.8-0.80.5-0.1
Intermittent access day 15 total infusions0.81.33.9-0.31.0-0.80.90.61.11.52.01.11.21.21.21.21.21.21.21.20.70.9
Intermittent access terminal intake (last 3 days)0.40.62.5-0.30.7-0.60.70.40.80.91.60.70.70.70.70.70.80.70.70.80.10.3
Intermittent access total infusions0.60.72.0-0.90.3-1.21.3-0.10.50.71.30.51.40.60.60.60.70.60.60.70.90.7
Intermittent access day 1 locomotion1.21.55.0-1.9-1.3-2.22.2-1.7-1.1-0.70.3-0.91.9-0.9-0.9-0.9-0.8-0.8-0.7-0.70.4-0.2
Intermittent access day 15 total locomotion0.61.04.2-1.5-0.1-2.02.1-0.7-0.00.61.60.12.00.20.20.20.50.50.30.30.70.4
Intermittent access total locomotion0.70.93.7-1.5-0.7-1.91.9-1.2-0.50.00.8-0.31.8-0.4-0.4-0.4-0.2-0.1-0.1-0.00.70.2
Intermittent access standard deviation0.00.00.2-0.10.1-0.10.10.30.2-0.00.40.2-0.00.10.20.20.10.00.10.2-0.2-0.1
Left kidney weight1.25.613.9-3.7-2.9-3.33.2-3.3-2.6-1.9-1.0-2.72.5-1.7-1.9-1.9-1.8-1.8-2.1-2.20.2-1.1
Right kidney weight1.04.512.6-3.5-2.4-3.53.5-3.0-2.1-1.40.0-2.12.8-1.3-1.3-1.3-1.4-1.3-1.6-1.70.2-0.9
Cocaine induced anxiety2.02.94.8-0.9-1.7-0.20.1-1.5-1.7-2.2-1.8-2.1-0.7-1.9-1.9-1.9-1.5-1.8-2.2-2.2-1.7-2.1
Post-drug Anxiety0.30.30.8-0.3-0.40.0-0.1-0.2-0.4-0.9-0.6-0.7-0.5-0.5-0.5-0.5-0.3-0.6-0.8-0.8-0.9-0.9
Baseline Anxiety6.17.010.71.22.90.4-0.33.02.93.02.83.10.73.13.13.12.72.93.33.32.23.0
Tail length3.212.522.1-4.3-4.5-3.43.3-4.7-4.1-3.7-2.7-4.22.1-3.5-3.4-3.4-3.5-3.6-3.6-3.7-0.6-2.4
Length with tail4.218.233.6-4.8-5.3-4.34.1-5.8-5.1-3.9-2.4-4.92.6-4.4-4.4-4.4-4.4-4.3-4.3-4.5-1.3-3.3
Length without tail1.34.29.8-1.8-2.4-2.02.0-3.1-2.4-1.2-0.4-2.31.3-2.2-2.3-2.3-2.0-2.0-2.2-2.2-1.4-2.2
Times rat made contact with spout0.30.40.9-0.50.3-0.90.9-0.00.40.30.70.20.90.60.60.60.80.40.40.40.60.5
Lifetime Intake0.70.83.2-1.4-0.0-1.71.7-0.50.20.41.10.31.80.40.40.40.50.40.50.51.10.8
Liver weight, left0.30.51.1-1.0-0.9-1.01.0-1.0-0.9-0.5-0.3-0.90.8-0.6-0.5-0.5-0.5-0.5-0.7-0.60.1-0.4
Liver weight, right0.91.62.8-0.80.7-1.21.30.31.11.11.61.01.71.51.51.51.31.51.21.11.61.5
Locomotor activity1.21.86.80.11.5-0.80.91.01.31.62.61.41.21.51.41.41.61.41.51.50.40.9
Locomotor testing distance0.61.04.50.31.2-0.70.70.80.91.12.11.10.91.11.01.01.11.11.21.00.20.6
Locomotor testing rearing0.00.10.4-0.30.0-0.40.40.2-0.2-0.1-0.1-0.00.40.00.00.00.20.10.20.10.60.5
Locomotion in novel chamber0.10.10.5-0.6-0.3-0.00.0-0.1-0.4-0.6-0.7-0.2-0.0-0.3-0.3-0.3-0.1-0.4-0.2-0.00.40.3
Locomotion in novel chamber post-restriction0.10.20.9-0.7-0.5-0.30.3-0.1-0.5-0.2-0.7-0.20.5-0.2-0.2-0.2-0.2-0.30.00.20.90.6
Fecal boli incidents, locomotor time 10.40.62.11.50.81.0-1.00.60.90.90.70.9-0.70.70.70.70.10.80.60.9-0.5-0.0
Change in fecal boli incidents, locomotor task0.30.31.0-0.80.2-0.80.80.6-0.00.10.40.30.90.20.20.20.40.30.50.31.00.8
Time >=10cm from walls, locomotor time 10.60.61.80.10.8-0.40.40.60.60.81.31.00.60.70.60.60.90.71.11.10.50.7
Bouts of movement, locomotor time 10.70.81.50.91.00.5-0.50.71.21.20.91.0-0.11.11.11.10.81.10.90.80.20.6
Total resting periods, locomotor time 10.60.71.31.10.90.8-0.70.81.01.00.70.9-0.40.90.90.90.60.80.90.80.10.5
Rest time, locomotor task time 11.31.62.40.91.50.6-0.61.51.51.31.11.5-0.11.51.51.51.31.61.41.50.71.2
Distance moved, locomotor task time 10.60.81.7-0.8-0.8-0.90.9-1.3-0.8-0.60.1-1.10.4-0.8-0.8-0.8-0.7-0.9-1.1-1.3-1.1-1.3
Vertical activity count, locomotor time 10.00.10.3-0.3-0.3-0.40.4-0.6-0.20.1-0.1-0.40.3-0.2-0.2-0.2-0.0-0.0-0.3-0.4-0.0-0.2
Time >=10cm from walls, locomotor time 20.30.52.00.5-0.4-0.0-0.0-0.7-0.7-0.40.2-0.6-0.4-0.7-0.8-0.8-0.6-0.8-0.7-0.7-1.4-1.3
Bouts of movement, locomotor time 20.10.10.40.50.40.6-0.60.10.40.50.20.4-0.40.10.10.10.40.00.30.2-0.20.0
Total resting periods, locomotor time 20.00.10.20.40.30.4-0.4-0.00.30.40.30.3-0.30.10.10.10.3-0.10.20.1-0.3-0.1
Rest time, locomotor task time 22.02.64.62.12.11.6-1.51.82.01.81.81.9-1.11.51.51.51.51.61.51.6-0.60.4
Distance moved, locomotor task time 21.21.53.1-1.6-1.3-1.81.7-1.8-1.2-1.0-0.2-1.51.3-0.8-0.9-0.9-0.9-0.9-1.2-1.5-0.3-0.9
Vertical activity count, locomotor time 20.40.62.0-1.4-1.0-0.90.9-1.0-0.7-0.6-0.8-1.00.8-0.4-0.4-0.4-0.3-0.4-0.7-0.90.60.0
Light reinforcement 10.51.23.00.31.2-0.10.21.01.11.51.00.90.71.41.41.41.71.21.20.91.11.2
Light reinforcement 21.32.04.60.31.5-0.30.41.11.62.12.01.30.91.81.71.71.91.61.51.30.81.1
Bone: marrow area0.00.00.1-0.10.0-0.10.00.0-0.0-0.00.1-0.1-0.0-0.0-0.0-0.0-0.1-0.1-0.1-0.1-0.3-0.2
Bone: maximum diameter0.81.53.7-1.9-1.6-1.21.2-1.3-1.5-1.4-1.3-1.50.8-1.1-1.1-1.1-1.1-1.3-1.2-1.20.3-0.4
Bone: maximum force0.50.83.5-1.6-0.3-1.81.9-0.6-0.20.41.2-0.11.80.20.20.20.30.20.20.20.60.2
Bone: maximum moment0.50.83.4-1.7-0.6-1.91.9-0.9-0.50.00.8-0.41.7-0.2-0.2-0.2-0.1-0.2-0.2-0.20.4-0.0
Mean time between licks in bursts0.40.94.21.80.61.5-1.50.60.3-0.10.40.3-1.7-0.2-0.2-0.2-0.2-0.1-0.2-0.2-2.1-1.3
Mean num. licks in bursts0.10.20.70.5-0.10.4-0.4-0.1-0.2-0.5-0.3-0.2-0.7-0.5-0.5-0.5-0.5-0.4-0.4-0.4-0.8-0.7
Cd content in liver10.211.318.6-4.1-4.3-3.13.0-4.2-4.1-3.5-3.1-4.02.0-3.4-3.4-3.4-3.3-3.5-3.5-3.40.1-1.7
Co content in liver1.51.83.7-0.41.1-1.11.10.81.11.61.91.21.61.41.41.41.41.41.41.51.41.5
Cu content in liver2.93.48.22.92.22.7-2.62.42.11.60.81.9-2.11.61.51.51.51.51.61.5-0.60.5
Fe content in liver1.72.18.22.51.12.9-2.91.41.00.7-0.40.7-2.70.30.30.30.30.20.20.2-1.6-0.7
K content in liver0.50.52.01.40.61.4-1.40.80.30.70.00.4-1.2-0.0-0.0-0.00.00.00.20.2-0.9-0.4
Mg content in liver0.20.20.4-0.6-0.6-0.50.5-0.6-0.60.3-0.2-0.50.6-0.4-0.4-0.4-0.3-0.4-0.3-0.30.2-0.2
Mn content in liver0.80.81.5-0.5-1.1-0.10.1-0.9-1.1-0.7-1.2-1.1-0.1-1.1-1.1-1.1-1.1-1.1-1.1-1.1-0.3-0.7
Na content in liver1.21.34.52.11.21.9-1.91.31.10.90.31.0-1.70.60.60.60.50.80.60.6-0.8-0.1
Rb content in liver0.70.83.21.80.61.8-1.81.00.30.6-0.30.4-1.6-0.1-0.1-0.1-0.10.00.20.1-1.0-0.5
Se content in liver0.50.62.1-1.10.0-1.31.30.10.10.30.60.21.40.50.50.50.50.50.60.51.31.0
Sr content in liver2.01.74.2-0.2-1.20.7-0.7-1.0-1.2-1.6-2.1-1.4-1.2-1.4-1.4-1.4-1.4-1.4-1.5-1.5-1.0-1.3
Zn content in liver2.93.312.2-3.4-1.5-3.53.5-1.8-1.2-0.10.5-0.93.5-0.2-0.3-0.3-0.2-0.3-0.2-0.12.21.0
Bone: minimum diameter2.34.17.3-1.3-2.4-0.20.1-2.0-2.4-2.5-2.7-2.3-0.6-2.4-2.4-2.4-2.3-2.4-2.3-2.3-0.9-1.6
Time in familiar zone, hab. session 10.40.31.20.7-0.00.9-0.90.4-0.2-0.6-0.4-0.1-1.1-0.5-0.5-0.5-0.6-0.1-0.4-0.4-0.9-0.6
Time in novel zone, hab. session 11.01.03.0-1.7-1.2-1.61.6-1.3-1.0-0.9-0.3-1.01.3-0.7-0.7-0.7-0.6-1.0-0.8-0.80.3-0.3
Total zone transitions, hab. session 10.91.35.2-2.3-1.3-2.02.0-1.4-1.0-0.60.0-1.01.7-0.5-0.5-0.5-0.7-0.7-0.7-0.70.5-0.2
Total locomotion distance, hab. session 10.40.62.5-1.4-0.1-1.61.6-0.50.10.41.3-0.01.50.40.40.40.30.20.10.10.20.0
Locomotion velocity, hab. session 10.40.61.9-1.00.0-1.31.3-0.40.30.81.30.11.40.60.60.60.50.30.30.30.30.2
Time in familiar zone, hab. session 20.10.10.80.60.30.2-0.20.30.20.30.90.5-0.20.0-0.0-0.0-0.20.30.30.3-0.6-0.3
Time in novel zone, hab. session 21.41.42.7-1.3-1.5-0.70.6-1.4-1.4-1.4-1.6-1.60.2-1.2-1.1-1.1-1.0-1.5-1.4-1.4-0.1-0.7
Total zone transitions, hab. session 20.70.92.0-1.3-1.2-1.31.3-1.4-1.1-0.8-0.4-1.11.0-0.8-0.8-0.8-0.9-0.9-0.9-0.90.1-0.5
Total locomotion distance, hab. session 20.30.41.0-0.7-0.7-0.80.8-1.0-0.6-0.20.1-0.70.6-0.5-0.5-0.5-0.6-0.6-0.6-0.6-0.4-0.6
Locomotion velocity, hab. session 20.20.20.6-0.7-0.5-0.80.8-0.7-0.40.10.2-0.50.7-0.2-0.2-0.2-0.4-0.3-0.3-0.30.0-0.3
Novel to familiar place preference ratio0.30.31.0-0.9-0.1-0.90.9-0.20.0-0.10.0-0.11.00.40.40.40.50.20.10.11.00.6
Novelty place preference0.40.41.6-1.2-0.3-1.31.3-0.4-0.2-0.2-0.0-0.31.20.20.30.30.30.10.0-0.01.10.6
Time in novel zone, NPP test0.40.41.7-1.2-0.4-1.31.3-0.5-0.3-0.4-0.1-0.41.20.10.10.10.2-0.1-0.1-0.11.00.5
Total zone transitions, NPP test1.21.86.4-2.4-1.3-2.52.5-1.6-1.1-0.60.2-0.82.3-0.6-0.6-0.6-0.6-0.5-0.4-0.41.20.4
Total locomotion distance, NPP test0.50.72.3-1.5-0.8-1.51.5-1.2-0.6-0.30.1-0.61.3-0.3-0.3-0.3-0.4-0.5-0.4-0.40.4-0.0
Locomotion velocity, NPP test0.40.51.7-1.3-0.6-1.31.3-1.1-0.4-0.20.2-0.51.2-0.2-0.2-0.2-0.2-0.4-0.3-0.30.3-0.1
Intraocular pressure1.21.72.70.71.4-0.00.11.31.51.41.61.50.51.61.61.61.41.51.51.60.81.2
Delta distance traveled before/after self-admin0.20.21.40.80.20.6-0.60.00.2-0.20.20.1-0.8-0.2-0.2-0.2-0.1-0.1-0.20.0-1.2-0.8
Delta ambulatory time before/after self-admin0.30.41.41.20.51.0-1.00.20.40.30.30.3-1.00.10.10.10.10.10.00.3-1.1-0.6
Parametrial fat weight0.10.20.7-0.5-0.4-0.60.6-0.5-0.2-0.80.2-0.30.2-0.2-0.2-0.2-0.4-0.0-0.3-0.6-0.3-0.3
Pavlov. Cond. lever latency3.13.96.82.12.61.4-1.42.42.42.52.32.4-0.71.92.02.02.12.02.12.1-0.10.9
Pavlov. Cond. magazine entry latency4.45.69.2-1.3-2.8-0.60.4-2.6-2.7-3.0-2.4-2.7-0.5-2.7-2.8-2.8-2.8-2.7-2.7-2.7-1.6-2.3
Pavlov. Cond. change in total contacts4.44.78.2-1.8-2.9-1.00.9-2.4-2.7-2.8-2.7-2.60.2-2.3-2.4-2.4-2.6-2.3-2.4-2.3-0.3-1.3
Pavlov. Cond. index score3.74.68.7-1.6-2.7-0.70.6-2.3-2.5-3.0-2.8-2.5-0.1-2.3-2.4-2.4-2.5-2.3-2.4-2.4-0.6-1.5
Pavlov. Cond. latency score3.74.78.8-1.7-2.7-0.80.7-2.4-2.6-3.0-2.8-2.6-0.1-2.3-2.4-2.4-2.5-2.3-2.5-2.4-0.5-1.5
Pavlov. Cond. lever contacts1.92.23.9-1.6-2.0-1.00.9-1.7-1.8-2.0-1.8-1.80.5-1.4-1.5-1.5-1.7-1.5-1.6-1.60.1-0.7
Pavlov. Cond. magazine entry number4.25.39.91.42.70.5-0.32.42.63.12.52.60.62.62.62.62.62.62.72.71.62.2
Pavlov. Cond. intertrial magazine entries0.70.82.00.51.00.1-0.00.80.91.41.21.00.41.01.01.01.00.91.11.10.50.7
Pavlov. Cond. lever-magazine prob. diff.3.74.68.2-1.9-2.7-1.10.9-2.4-2.6-2.9-2.5-2.50.2-2.3-2.4-2.4-2.5-2.2-2.4-2.3-0.5-1.4
Pavlov. Cond. response bias4.04.98.6-1.8-2.7-1.00.8-2.5-2.6-2.9-2.3-2.6-0.0-2.4-2.5-2.5-2.5-2.5-2.5-2.5-1.1-1.9
Pavlov. Cond. lever latency1.21.73.61.91.71.5-1.51.41.61.51.21.4-1.11.21.21.21.11.21.01.0-0.80.1
Pavlov. Cond. magazine entry latency0.50.61.4-0.6-1.1-0.80.8-1.2-1.0-0.6-0.4-0.90.6-0.8-0.8-0.8-0.9-0.9-0.8-0.8-0.2-0.6
Pavlov. Cond. change in total contacts0.10.20.8-0.4-0.5-0.10.1-0.1-0.6-0.6-0.9-0.40.0-0.4-0.5-0.5-0.5-0.4-0.3-0.20.60.3
Pavlov. Cond. index score1.11.52.5-1.3-1.6-1.11.1-1.6-1.5-1.2-1.0-1.40.8-1.3-1.2-1.2-1.2-1.3-1.2-1.10.1-0.6
Pavlov. Cond. latency score1.21.62.8-1.2-1.7-1.00.9-1.7-1.6-1.3-1.2-1.50.6-1.4-1.3-1.3-1.3-1.4-1.4-1.3-0.1-0.8
Pavlov. Cond. lever contacts1.01.43.0-1.7-1.5-1.41.4-1.2-1.5-1.3-1.1-1.21.1-1.1-1.0-1.0-1.0-1.1-0.9-0.90.7-0.0
Pavlov. Cond. magazine entry number0.30.40.80.50.80.6-0.60.90.80.40.40.7-0.50.70.70.70.60.70.60.6-0.00.4
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.1-0.40.2-0.2-0.2-0.3-0.6-0.8-0.4-0.3-0.4-0.4-0.4-0.3-0.3-0.4-0.4-0.0-0.2
Pavlov. Cond. lever-magazine prob. diff.0.81.11.9-1.1-1.4-1.00.9-1.4-1.3-1.0-0.9-1.20.7-1.1-1.1-1.1-1.1-1.1-1.0-0.90.1-0.5
Pavlov. Cond. response bias0.81.11.9-1.3-1.3-1.41.3-1.2-1.3-1.0-0.6-1.11.1-1.0-1.0-1.0-1.0-1.0-0.8-0.80.4-0.2
Time in closed arm before self-admin0.10.20.50.30.50.3-0.20.60.30.7-0.10.20.10.50.50.50.50.50.10.30.50.4
Time in closed arm after self-admin2.02.23.71.41.90.7-0.61.71.81.91.91.6-0.11.71.71.71.71.61.41.40.10.8
Time in open arm before self-admin0.30.30.5-0.7-0.7-0.70.7-0.7-0.5-0.60.2-0.40.4-0.6-0.6-0.6-0.6-0.6-0.3-0.3-0.3-0.4
Time in open arm after self-admin3.53.88.4-2.2-2.5-1.31.2-1.9-2.4-2.9-2.5-2.10.4-2.1-2.1-2.1-2.2-2.1-1.8-1.80.2-0.8
Bone: periosteal estimation0.61.32.9-1.7-1.4-1.31.3-1.3-1.4-1.1-0.7-1.30.9-1.1-1.1-1.1-1.1-1.2-1.1-1.1-0.0-0.6
Bone: periosteal perimeter1.01.63.1-1.8-1.6-1.21.2-1.4-1.5-1.3-1.0-1.50.7-1.3-1.3-1.3-1.2-1.4-1.3-1.3-0.1-0.7
Bone: post-yield work0.00.00.20.10.10.1-0.10.3-0.00.40.10.10.00.00.00.00.0-0.00.10.20.10.1
Progressive ratio test 1 active lever presses0.81.02.4-0.8-1.1-0.80.7-1.5-1.0-0.8-0.3-1.00.3-1.1-1.1-1.1-0.9-1.1-1.1-1.1-0.9-1.1
Progressive ratio test 1 breakpoint0.70.82.2-0.9-1.0-0.80.8-1.5-0.9-0.8-0.2-0.90.4-1.0-1.0-1.0-0.8-1.0-1.0-0.9-0.7-1.0
Progressive ratio test 1 inactive lever presses1.92.74.0-1.7-2.0-1.21.1-2.0-1.9-2.0-1.3-1.80.4-1.9-1.8-1.8-1.9-1.9-1.8-1.6-0.7-1.3
Progressive ratio test 2 active lever presses0.30.31.6-1.3-0.6-1.01.0-0.8-0.3-0.60.0-0.60.8-0.2-0.2-0.20.1-0.2-0.5-0.40.1-0.2
Progressive ratio test 2 breakpoint0.20.31.4-1.2-0.4-1.00.9-0.7-0.2-0.40.1-0.40.7-0.1-0.1-0.10.2-0.1-0.4-0.30.1-0.1
Progressive ratio test 2 inactive lever presses1.01.65.3-2.3-1.3-2.32.3-1.6-1.0-0.60.4-1.11.9-0.7-0.7-0.7-0.6-0.7-0.9-0.60.2-0.4
Incentive Sensitization - Responses0.20.31.3-1.1-0.3-1.01.0-0.4-0.0-0.30.4-0.30.80.10.20.20.30.1-0.3-0.20.1-0.1
Incentive Sensitization - Breakpoint0.20.21.1-1.1-0.3-0.90.9-0.4-0.0-0.30.3-0.40.70.10.10.10.20.1-0.4-0.30.0-0.2
Sum of active levers in priming session hrs 5-62.72.55.5-2.0-1.8-2.32.3-2.0-1.9-1.3-0.1-1.51.7-1.7-1.6-1.6-1.6-1.4-1.2-0.9-0.1-0.9
Progressive ratio2.64.116.0-3.1-0.2-3.03.1-0.20.20.70.80.43.71.21.21.21.11.31.21.24.03.0
Food seeking constrained by brief footshock0.50.62.41.10.21.5-1.50.20.1-0.2-0.7-0.0-1.5-0.3-0.3-0.3-0.1-0.4-0.2-0.5-1.0-0.7
Seeking ratio, punishment vs. effort2.63.713.83.10.43.0-3.10.4-0.1-0.6-0.7-0.2-3.5-1.1-1.1-1.1-1.0-1.1-1.0-1.1-3.7-2.7
Retroperitoneal fat weight0.73.08.2-2.7-2.0-2.92.8-2.7-1.6-1.1-0.0-1.82.3-1.0-1.0-1.0-0.9-0.9-1.4-1.60.2-0.8
Reaction time number correct1.22.47.4-2.3-2.0-1.11.1-1.2-1.8-1.9-2.7-1.31.0-1.2-1.2-1.2-1.2-1.1-0.9-0.72.21.1
Reaction time mean minus median1.64.07.72.02.51.1-1.01.92.42.82.72.3-0.32.22.12.12.22.22.12.1-0.10.9
Reaction time mean minus median AUC1.23.05.22.22.21.6-1.51.72.12.31.92.0-0.91.71.71.71.71.71.71.8-0.40.6
Reaction time num false alarms1.31.94.71.51.51.7-1.72.21.40.80.21.7-1.21.21.21.20.91.31.51.50.91.5
Reaction time num false alarms AUC1.52.35.51.51.81.4-1.42.31.61.00.72.0-0.91.51.41.41.21.61.81.81.01.7
Reaction time trials correct on left1.22.47.4-2.3-2.0-1.11.1-1.2-1.8-1.9-2.7-1.31.0-1.2-1.2-1.2-1.2-1.1-0.9-0.72.21.1
Reaction time trials on left1.22.26.8-2.3-1.9-1.11.1-1.1-1.8-1.8-2.6-1.21.0-1.1-1.2-1.2-1.1-1.0-0.8-0.62.31.1
Reaction time mean3.45.410.22.83.11.7-1.61.93.13.03.22.6-1.02.52.52.52.42.32.12.1-1.20.2
Reaction time mean AUC3.65.710.22.73.11.7-1.62.13.23.03.12.7-0.92.62.62.62.52.52.32.2-0.80.6
Median of all reaction times2.83.97.52.52.61.7-1.71.62.72.42.62.1-1.22.12.02.01.91.81.61.6-1.4-0.1
Reaction time omissions1.42.15.11.21.70.5-0.41.11.62.31.81.70.31.61.61.61.61.51.61.60.61.1
Reaction time false alarm rate2.02.85.22.22.21.7-1.62.32.01.61.72.0-1.21.61.51.51.31.61.71.6-0.40.7
Reaction time premature initiation rate0.30.42.30.70.10.5-0.50.1-0.2-0.20.3-0.1-0.8-0.6-0.5-0.5-0.4-0.4-0.3-0.3-1.5-1.2
Reaction time premature initiations0.20.30.8-0.6-0.6-0.20.2-0.2-0.8-0.9-0.9-0.4-0.1-0.8-0.7-0.7-0.6-0.5-0.4-0.30.1-0.1
Std. dev. reaction times3.46.414.81.83.10.5-0.42.13.13.43.93.00.42.92.92.92.82.82.82.80.31.4
Reaction time trials completed1.22.26.8-2.3-1.9-1.11.1-1.1-1.8-1.8-2.6-1.21.0-1.1-1.2-1.2-1.1-1.0-0.8-0.62.31.1
Reaction time trials AUC1.32.47.9-2.3-2.0-1.11.1-1.2-1.9-1.9-2.8-1.31.0-1.2-1.2-1.2-1.3-1.1-0.9-0.72.31.1
Run reversals in cocaine runway, females0.10.10.3-0.4-0.3-0.20.2-0.1-0.2-0.6-0.2-0.3-0.1-0.3-0.3-0.3-0.2-0.1-0.4-0.2-0.2-0.2
Run reversals in cocaine runway, males0.40.41.10.90.51.0-1.00.10.70.70.30.3-0.90.40.40.40.50.30.00.0-1.1-0.7
Latency to leave start box in cocaine runway0.91.03.21.71.11.8-1.81.30.80.9-0.10.9-1.40.60.60.60.50.60.90.7-0.20.3
Latency to leave start box in cocaine runway, F2.02.35.52.31.91.7-1.61.71.61.71.31.7-1.11.31.31.31.31.41.71.4-0.40.4
Latency to leave start box in cocaine runway, M0.40.41.90.1-0.40.8-0.8-0.0-0.5-0.4-1.4-0.5-0.8-0.5-0.5-0.5-0.6-0.6-0.5-0.5-0.1-0.2
Std. dev. time between licks in bursts0.60.82.50.7-0.60.9-0.9-0.5-0.6-0.7-0.7-0.6-1.2-0.9-0.9-0.9-1.0-0.9-0.9-0.9-1.6-1.4
Total sessions with >9 infusions1.21.44.1-2.0-1.3-2.01.9-1.7-1.1-0.9-0.1-1.01.6-0.8-0.8-0.8-0.7-0.8-0.8-0.80.5-0.1
Short access day 1 total inactive lever presses0.20.21.0-0.6-0.1-0.90.9-0.80.10.01.0-0.10.70.10.10.10.1-0.0-0.1-0.1-0.5-0.5
Short access day 10 total inactive lever presses0.51.33.1-0.6-1.3-0.10.1-0.8-1.3-1.8-1.5-1.2-0.4-1.3-1.3-1.3-1.4-1.3-1.2-1.2-0.5-0.9
Short access day 1 total infusions0.60.82.3-1.5-0.9-1.51.5-1.4-0.7-0.70.0-0.71.2-0.5-0.5-0.5-0.3-0.5-0.5-0.50.4-0.0
Short access day 10 total infusions0.60.71.8-1.3-1.0-1.41.4-1.2-0.9-0.4-0.1-0.61.2-0.7-0.7-0.7-0.6-0.7-0.4-0.40.60.1
Short access total infusions0.91.14.2-1.8-0.9-2.12.1-1.3-0.7-0.30.4-0.51.9-0.4-0.4-0.4-0.3-0.3-0.2-0.31.10.5
Short access day 1 locomotion2.02.57.0-2.7-2.1-2.12.1-2.3-1.7-1.5-1.2-1.61.8-1.2-1.2-1.2-1.1-1.3-1.1-1.01.10.1
Short access day 10 total locomotion0.00.10.30.60.00.2-0.2-0.20.10.20.20.1-0.2-0.1-0.1-0.1-0.0-0.20.1-0.1-0.5-0.3
Short access total locomotion0.50.72.4-1.3-0.8-1.51.5-1.0-0.6-0.30.2-0.41.4-0.4-0.4-0.4-0.3-0.4-0.1-0.20.80.3
One hour access (0.3 mA shock)0.80.91.4-1.2-1.2-0.80.8-1.2-1.1-0.8-0.6-1.10.5-1.1-1.1-1.1-1.0-1.0-1.1-0.9-0.5-0.9
Compulsive drug intake3.13.65.90.3-1.80.9-1.0-1.3-1.9-2.0-2.4-1.8-1.7-2.3-2.3-2.3-2.4-2.2-2.0-2.1-1.9-2.1
One hour access (shock baseline)0.71.12.5-0.50.9-0.80.90.51.11.21.60.91.21.31.21.21.41.11.01.10.80.9
Social response proportion0.10.10.30.50.10.5-0.50.20.10.1-0.50.0-0.40.0-0.0-0.00.0-0.0-0.1-0.1-0.0-0.0
Social responses0.70.95.0-0.1-0.90.7-0.7-0.7-0.9-0.8-2.2-1.2-0.8-0.9-0.9-0.9-0.6-1.0-1.1-1.2-0.1-0.6
Social time0.10.21.1-0.4-0.50.1-0.2-0.3-0.5-0.4-1.1-0.5-0.1-0.4-0.5-0.5-0.2-0.4-0.5-0.40.30.0
Soleus weight2.47.012.00.82.60.10.02.62.72.82.12.81.23.23.13.13.03.33.23.23.13.5
Bone: stiffness0.40.72.8-1.6-0.7-1.71.7-0.8-0.8-0.40.4-0.71.4-0.4-0.4-0.4-0.4-0.4-0.4-0.40.3-0.1
Tibialis anterior weight0.62.24.1-0.4-1.5-0.20.1-1.2-1.7-1.8-1.3-1.5-0.5-1.9-2.0-2.0-1.9-1.6-1.5-1.6-1.4-1.6
Time to tail flick, vehicle, before self-admin1.61.76.72.61.51.8-1.81.41.21.51.21.2-1.50.60.60.60.60.80.80.9-1.5-0.5
Time to tail flick, vehicle, after self-admin0.30.51.7-1.2-0.7-1.31.3-0.8-0.5-0.30.2-0.61.1-0.2-0.2-0.2-0.3-0.3-0.4-0.40.3-0.1
Time to tail flick, test, before self-admin1.01.14.10.21.0-0.60.60.41.21.62.00.90.91.11.11.11.21.30.90.80.00.3
Time to tail flick, test, after self-admin0.20.31.9-0.20.2-0.70.7-0.20.20.71.40.20.70.20.20.20.20.30.1-0.1-0.5-0.4
Delta time to tail flick, vehicle, before/after SA1.31.34.4-2.1-1.3-1.91.9-1.3-1.1-0.9-0.3-1.01.6-0.5-0.5-0.5-0.6-0.7-0.7-0.70.80.1
Delta time to tail flick, test, before/after SA0.10.10.4-0.6-0.4-0.60.6-0.2-0.5-0.5-0.1-0.30.5-0.2-0.2-0.2-0.4-0.3-0.2-0.30.30.1
Tibia length1.54.06.2-2.2-2.5-1.71.6-2.5-2.4-2.4-1.6-2.30.8-2.2-2.2-2.2-2.0-2.1-2.0-2.1-0.5-1.4
Ambulatory time before self-admin1.31.95.9-1.30.4-1.92.00.20.51.11.50.82.41.11.01.01.11.11.21.12.31.9
Ambulatory time after self-admin1.41.63.60.11.2-0.70.80.81.31.51.91.41.21.41.41.41.31.51.41.61.21.4
Bone: tissue strength0.40.42.20.50.8-0.10.00.20.60.81.50.4-0.10.40.40.40.70.30.20.2-1.2-0.8
Total heroin consumption3.03.59.2-3.0-2.2-2.92.8-2.5-2.0-1.6-0.5-1.82.3-1.5-1.5-1.5-1.5-1.3-1.4-1.50.6-0.5
Bone: trabecular number0.30.51.9-0.30.3-0.70.70.30.30.60.30.31.00.70.70.70.60.70.70.71.41.1
Bone: trabecular spacing1.11.42.6-1.0-1.2-0.80.7-1.6-1.1-1.3-0.5-1.30.1-1.2-1.2-1.2-1.2-1.4-1.5-1.5-1.3-1.6
Bone: trabecular thickness0.40.52.5-0.60.2-0.60.70.50.2-0.10.10.50.80.60.60.60.50.70.80.81.61.4
Bone: trabecular tissue density1.31.87.71.90.12.0-2.00.1-0.1-0.3-0.4-0.3-2.4-0.9-0.9-0.9-0.8-0.9-0.9-0.8-2.8-2.1
Water consumed over 24 hours0.30.41.5-1.2-0.5-1.11.1-0.5-0.3-0.1-0.1-0.41.10.20.20.20.2-0.0-0.1-0.10.90.5
Number of responses in last shaping day0.90.92.9-0.90.5-0.70.80.30.70.50.60.81.10.90.90.91.20.91.01.11.71.6