Hub : Genes

LOC100911718

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA XM_063280353.1 0.22 0 0.0e+00 0.36 0.41 0.42 0.42 4.9e-42 1.1e-48 8.1e-50 7.4e-50
2 Liver alternative polyA XM_063280359.1 0.21 0 0.0e+00 0.37 0.41 0.42 0.42 1.0e-42 1.9e-49 1.0e-50 1.2e-50
3 Liver intron excision ratio chr1_247013856_247014589 0.15 0.02 0.0e+00 0.49 0.52 0.52 0.52 1.9e-62 1.6e-66 3.1e-66 5.6e-67
4 Liver intron excision ratio chr1_247013856_247015572 0.15 0.01 0.0e+00 0.53 0.54 0.54 0.54 1.9e-69 2.9e-70 2.5e-71 2.5e-71
5 Liver isoform ratio XM_063280359.1 0.13 0.02 0.0e+00 0.33 0.36 0.36 0.36 4.6e-37 6.3e-41 7.1e-42 1.6e-41
6 Liver isoform ratio XR_010061283.1 0.13 0.02 0.0e+00 0.21 0.26 0.25 0.27 1.6e-22 9.8e-29 6.2e-28 1.2e-29
7 Liver mRNA stability LOC100911718 0.2 0.02 8.8e-05 0.03 0.03 0.02 0.03 1.8e-04 5.5e-04 9.0e-04 2.1e-04
8 Liver isoform ratio XM_063280352.1 0.18 0.02 0.0e+00 0.48 0.52 0.52 0.49 7.2e-60 5.6e-67 2.4e-67 1.1e-61
9 Liver isoform ratio XR_010061284.1 0.11 0.03 0.0e+00 0.21 0.23 0.24 0.23 1.0e-22 4.0e-25 8.9e-27 2.0e-25
10 Liver isoform ratio XM_063280354.1 0.09 0.01 0.0e+00 0.36 0.36 0.35 0.34 1.7e-41 5.9e-42 3.0e-40 5.5e-39
11 Liver intron excision ratio chr1_247037788_247053570 0.13 0.01 0.0e+00 0.18 0.32 0.33 0.33 2.1e-19 4.6e-36 2.1e-37 1.1e-37
12 Liver intron excision ratio chr1_247018300_247053570 0.13 0.01 0.0e+00 0.18 0.32 0.33 0.33 1.8e-19 3.8e-36 1.7e-37 8.5e-38
13 Liver gene expression LOC100911718 0.14 0.01 0.0e+00 0.38 0.48 0.49 0.49 3.3e-44 2.4e-59 5.9e-62 2.4e-62

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.01.93.5-1.8-1.7-1.81.9-1.7-1.7-1.21.51.60.60.1-0.1-0.4
Area under the delay curve0.81.33.30.60.50.7-0.8-0.2-0.41.3-0.3-0.3-1.81.8-1.8-1.7
BMI with tail0.82.95.1-2.2-2.1-2.12.1-2.2-2.3-1.21.92.00.20.4-0.4-0.8
BMI without tail0.00.20.4-0.5-0.6-0.60.6-0.5-0.5-0.40.60.60.00.0-0.0-0.1
Body weight0.31.22.8-0.5-0.6-0.60.6-0.10.6-1.50.60.21.7-1.71.71.6
Weight adjusted by age0.41.22.3-1.3-1.3-1.21.1-1.5-1.5-0.41.11.2-0.30.7-0.7-0.9
Bone surface1.32.54.8-2.1-1.9-2.12.2-1.7-1.5-1.71.51.71.2-0.60.60.2
Bone volume1.22.33.9-1.9-1.8-1.92.0-1.4-1.2-1.91.51.51.4-0.90.90.6
Breakpoint value in progressive ratio session0.61.11.91.41.41.3-1.31.11.10.9-1.3-1.1-0.60.4-0.5-0.1
Number of licking bursts0.72.15.40.80.70.8-0.8-0.1-0.61.9-0.4-0.2-2.32.3-2.3-2.2
Context. condit. distance diff. score0.20.30.6-0.7-0.6-0.70.7-0.5-0.5-0.80.60.50.5-0.20.20.1
Locomotion velocity, session 13.33.77.81.71.71.6-1.50.8-0.02.7-1.4-1.0-2.82.6-2.6-2.4
Locomotion distance, session 11.31.63.31.41.41.3-1.21.00.51.8-1.3-1.1-1.51.3-1.2-1.0
Locomotion velocity, session 21.01.22.70.90.90.7-0.60.4-0.21.6-0.9-0.5-1.61.6-1.6-1.5
Locomotion distance, session 20.40.61.30.60.60.6-0.60.3-0.11.0-0.6-0.4-1.11.1-1.1-1.0
Locomotion velocity, session 30.40.50.90.70.70.5-0.51.00.90.1-0.8-0.70.4-0.70.70.8
Locomotion distance, session 31.92.24.31.11.21.0-1.01.82.1-0.6-1.2-1.31.4-1.91.92.1
Stereotopy head waving bouts, day 30.00.10.20.20.20.2-0.30.10.10.4-0.1-0.2-0.30.3-0.3-0.2
Stereotopy head waving duration, day 30.30.31.00.20.10.2-0.2-0.2-0.30.8-0.00.0-0.91.0-1.0-0.9
Locomotion velocity, session 70.60.61.5-0.6-0.7-0.50.3-0.30.1-1.20.70.31.2-1.11.11.0
Locomotion distance, session 70.91.12.6-0.9-0.9-0.80.6-0.4-0.1-1.60.70.51.5-1.41.41.3
Stereotopy head waving bouts, day 71.51.83.11.61.51.6-1.61.00.81.8-1.1-1.2-1.51.2-1.2-0.9
Stereotopy head waving duration, day 70.81.01.61.31.21.2-1.20.90.71.3-0.9-1.0-1.00.7-0.7-0.5
Locomotion velocity, session 80.10.10.10.30.40.3-0.20.30.10.2-0.4-0.2-0.20.2-0.2-0.1
Locomotion distance, session 80.20.20.7-0.2-0.2-0.20.2-0.4-0.70.10.20.3-0.50.7-0.7-0.8
Degree of sensitization distance1.31.42.8-1.1-1.1-0.90.8-1.6-1.70.21.21.1-0.81.3-1.3-1.5
Degree of sensitization stereotypy2.02.23.61.91.71.9-1.91.31.01.8-1.3-1.5-1.51.1-1.1-0.8
Conditioned locomotion1.01.22.0-1.4-1.3-1.31.2-1.0-0.7-1.41.01.01.2-0.90.90.7
Cocaine response after cond. corrected0.10.10.30.10.00.1-0.1-0.1-0.20.3-0.00.0-0.50.5-0.5-0.5
Cocaine response after cond. not corrected0.20.30.50.70.70.7-0.60.70.50.5-0.7-0.6-0.40.2-0.2-0.1
Cocaine response before conditioning1.21.42.51.61.61.4-1.31.51.41.0-1.5-1.3-0.40.0-0.00.3
Saline control response1.52.13.81.91.91.7-1.61.71.21.6-1.8-1.5-1.00.7-0.7-0.4
Bone: connectivity density2.74.37.8-2.7-2.6-2.72.8-2.6-2.5-1.72.22.40.80.0-0.0-0.5
Bone: cortical apparent density0.81.23.00.60.60.6-0.50.0-0.51.4-0.4-0.2-1.71.7-1.7-1.7
Bone: cortical area1.11.74.8-0.1-0.1-0.20.20.71.2-1.5-0.1-0.32.0-2.22.22.2
Bone: cortical porosity1.61.73.2-1.0-1.1-0.90.9-1.6-1.80.51.21.2-1.21.6-1.6-1.8
Bone: cortical porosity0.70.81.4-0.8-0.8-0.70.7-1.1-1.20.20.90.8-0.70.9-0.9-1.1
Bone: cortical thickness1.93.15.92.12.12.0-2.02.42.40.7-1.9-2.00.3-1.01.01.4
Bone: cortical thickness2.42.95.02.22.12.2-2.21.81.51.9-1.9-1.8-1.30.8-0.8-0.4
Bone: cortical tissue density0.91.43.70.50.50.5-0.4-0.2-0.71.4-0.2-0.0-1.81.9-1.9-1.9
Condit. Reinf. active minus inactive responses0.20.20.30.60.60.4-0.30.50.60.6-0.6-0.5-0.20.2-0.2-0.0
Condit. Reinf. active-inactive response ratio0.00.00.10.10.2-0.00.10.20.40.1-0.2-0.10.1-0.10.10.2
Condit. Reinf. active responses0.10.10.30.50.50.3-0.20.50.60.4-0.5-0.4-0.1-0.00.00.1
Condit. Reinf. inactive responses0.10.10.30.30.30.3-0.30.20.00.6-0.3-0.2-0.50.4-0.4-0.4
Incentive salience index mean0.50.61.31.01.00.8-0.71.11.20.5-1.0-0.9-0.0-0.20.20.4
Condit. Reinf. lever presses0.60.91.61.31.21.1-1.11.21.20.6-1.1-1.1-0.3-0.10.10.3
Condit. Reinf. active minus inactive responses1.42.13.5-1.9-1.8-1.81.8-1.5-1.2-1.71.41.51.2-0.70.70.5
Condit. Reinf. active-inactive response ratio1.01.52.6-1.6-1.6-1.61.6-1.5-1.4-1.11.31.40.40.0-0.0-0.3
Condit. Reinf. active responses0.71.12.7-0.6-0.6-0.60.7-0.00.3-1.50.30.31.6-1.61.61.5
Condit. Reinf. inactive responses2.02.95.61.51.61.5-1.42.12.4-0.2-1.6-1.61.3-1.91.92.1
Condit. Reinf. lever presses0.50.81.51.11.11.0-0.91.21.10.2-1.1-1.00.2-0.40.40.6
Condit. Reinf. lever reinforcers received0.40.51.4-0.3-0.2-0.30.30.20.4-1.0-0.10.01.2-1.21.21.2
Conditioned reinforcement - actives0.10.51.01.01.00.9-0.90.80.90.6-0.8-0.8-0.1-0.10.10.2
Conditioned reinforcement - inactives0.30.71.21.11.01.1-1.10.70.71.1-0.8-0.8-0.80.6-0.6-0.4
Conditioned locomotion0.40.61.01.01.00.9-0.81.00.90.7-1.0-0.8-0.0-0.10.10.3
Patch foraging indifference point 0 sec0.41.02.31.11.11.0-1.11.31.50.2-0.9-1.10.4-0.80.81.1
Patch foraging indifference point AUC2.35.48.52.82.92.9-2.82.31.62.7-2.7-2.3-2.11.5-1.5-1.0
Delay disc. indifference point, 0s delay1.71.94.0-1.5-1.6-1.41.3-1.8-2.0-0.71.61.5-0.61.0-1.0-1.3
Delay disc. indifference point, 16s delay0.60.81.60.90.90.9-0.90.40.11.1-0.5-0.6-1.31.1-1.1-1.0
Delay disc. indifference point, 2s delay1.51.63.1-1.0-1.2-0.90.6-1.8-1.50.21.21.1-1.21.5-1.5-1.7
Delay disc. indifference point, 24s delay1.62.53.71.91.91.9-1.91.21.01.8-1.6-1.4-1.71.4-1.4-1.0
Delay disc. indifference point, 4s delay0.60.72.00.20.10.3-0.4-0.4-0.40.70.0-0.1-1.41.4-1.4-1.4
Delay disc. indifference point, 8s delay1.72.95.81.51.51.7-1.60.7-0.02.1-1.1-1.0-2.42.3-2.3-2.1
Indifference point function ln k1.44.16.2-2.4-2.4-2.52.4-1.9-1.2-2.42.32.01.9-1.51.51.1
Indifference point function log k1.44.16.2-2.4-2.4-2.52.4-1.9-1.2-2.42.32.01.9-1.51.51.1
Patch foraging total patch changes 0 sec0.41.22.71.21.11.0-1.11.41.60.1-0.9-1.10.6-1.01.01.2
Patch foraging total patch changes 12 sec3.24.26.82.62.52.6-2.62.11.62.4-2.4-2.1-1.61.1-1.1-0.7
Patch foraging total patch changes 18 sec0.71.72.91.51.51.5-1.41.10.61.7-1.4-1.2-1.41.1-1.1-0.9
Patch foraging total patch changes 24 sec0.51.62.71.51.51.5-1.51.61.60.8-1.5-1.50.0-0.40.40.7
Patch foraging total patch changes 6 sec3.96.511.23.33.33.4-3.32.92.42.5-2.9-2.8-1.50.7-0.7-0.2
Patch foraging time to switch 0 sec0.20.82.30.30.30.3-0.3-0.2-0.61.3-0.2-0.1-1.31.5-1.5-1.5
Patch foraging water rate 0 sec0.20.82.1-0.7-0.8-0.80.8-0.30.1-1.40.70.61.2-1.21.21.1
Patch foraging water rate 12 sec0.10.41.2-0.0-0.1-0.20.20.30.6-0.8-0.0-0.00.9-1.11.11.1
Patch foraging water rate 18 sec0.20.41.1-0.1-0.1-0.10.10.30.5-0.7-0.1-0.11.0-1.01.01.1
Patch foraging water rate 24 sec0.20.30.7-0.4-0.4-0.50.4-0.2-0.0-0.80.40.30.7-0.70.70.6
Patch foraging water rate 6 sec0.00.00.10.1-0.0-0.00.10.10.2-0.10.00.00.1-0.20.20.2
Seeking ratio, delayed vs. immediate footshock0.50.71.80.50.40.5-0.60.91.1-0.2-0.4-0.71.1-1.21.21.3
Distance traveled before self-admin0.10.30.7-0.5-0.5-0.30.2-0.6-0.80.20.40.3-0.30.6-0.7-0.7
Distance traveled after self-admin0.51.02.0-1.3-1.2-1.21.1-1.4-1.2-0.61.01.20.20.3-0.3-0.4
Extensor digitorum longus weight0.20.71.4-1.1-1.0-1.11.2-1.0-0.7-0.80.80.90.8-0.40.40.3
Bone: elastic displacement0.91.12.3-1.1-1.1-1.11.2-1.2-1.5-0.21.11.2-0.50.8-0.8-1.1
Bone: elastic work0.40.61.3-0.8-0.8-0.90.9-0.9-1.1-0.40.80.8-0.30.5-0.5-0.7
Bone: endosteal estimation2.15.18.6-2.9-2.8-2.82.8-2.4-1.8-2.62.42.31.8-1.21.20.7
Bone: endosteal perimeter2.25.38.8-3.0-2.8-2.92.9-2.4-1.8-2.72.42.31.9-1.21.20.8
Epididymis fat weight0.73.35.5-2.1-2.2-2.32.3-1.7-1.1-2.42.11.81.7-1.11.10.8
Delta time in closed arm before/after self-admin0.40.31.20.50.40.4-0.40.51.10.0-0.4-0.60.4-0.70.70.9
Delta time in open arm before/after self-admin0.50.61.5-1.0-1.0-0.80.8-1.1-1.2-0.50.90.90.10.3-0.3-0.5
Diff in mean of infusions in LGA sessions0.10.20.6-0.6-0.5-0.50.6-0.5-0.1-0.20.30.40.8-0.50.50.5
Delay discount exponential model param0.91.23.2-0.7-0.6-0.80.90.10.2-1.30.40.41.8-1.71.71.6
Extinction: sum of active levers before priming0.30.41.20.40.40.4-0.40.51.10.1-0.4-0.50.7-0.80.81.0
Active lever presses in extinction session 62.22.24.8-1.4-1.3-1.31.4-1.9-2.2-0.21.11.6-0.91.6-1.6-1.8
Bone: final force0.20.40.90.30.20.4-0.50.60.8-0.4-0.2-0.50.7-0.90.91.0
Bone: final moment0.30.41.20.10.00.2-0.30.40.7-0.7-0.0-0.30.9-1.11.11.1
Food consumed during 24 hour testing period0.71.42.61.51.61.4-1.31.61.40.9-1.5-1.3-0.2-0.10.10.4
Glucose0.40.71.90.20.30.2-0.20.70.9-0.5-0.4-0.41.1-1.31.31.4
Heart weight0.91.44.0-0.1-0.2-0.20.20.51.1-1.20.1-0.21.8-2.02.02.0
Delay discount hyperbolic model param0.71.02.6-0.4-0.3-0.50.60.30.4-1.00.10.11.6-1.61.61.5
Intermittent access intake day 1-15 change0.21.01.7-1.3-1.3-1.31.3-0.9-0.8-1.01.01.10.8-0.60.50.4
Intermittent access intake escalation0.31.52.5-1.6-1.6-1.61.5-1.2-1.0-1.31.41.31.0-0.70.70.5
Intermittent access intake escalation 20.81.32.3-1.5-1.5-1.51.5-1.3-1.0-1.21.31.20.6-0.40.40.2
Intermitt. access day 1 inactive lever presses0.00.30.9-0.5-0.4-0.60.8-0.4-1.0-0.30.30.70.00.5-0.5-0.6
Intermitt. access day 15 inactive lever presses0.10.30.9-0.4-0.3-0.50.6-0.1-0.0-0.80.30.41.0-0.70.70.6
Intermitt. access escalation Index0.10.40.8-0.7-0.6-0.70.7-0.4-0.3-0.90.50.50.7-0.60.60.5
Intermittent access day 1 total infusions0.00.10.30.20.20.2-0.2-0.0-0.20.10.10.1-0.20.5-0.4-0.5
Intermittent access day 15 total infusions0.41.02.3-0.9-0.9-0.90.9-0.50.1-1.31.00.71.5-1.31.31.2
Intermittent access terminal intake (last 3 days)0.20.30.6-0.4-0.5-0.50.5-0.30.0-0.60.60.40.8-0.60.60.6
Intermittent access total infusions0.10.10.4-0.2-0.2-0.20.3-0.1-0.0-0.50.40.30.6-0.40.40.3
Intermittent access day 1 locomotion0.20.40.9-0.6-0.6-0.70.7-0.4-0.2-0.90.70.61.0-0.60.70.5
Intermittent access day 15 total locomotion0.10.50.70.80.80.8-0.70.50.20.8-0.7-0.5-0.80.8-0.8-0.6
Intermittent access total locomotion0.20.20.60.00.10.10.0-0.2-0.50.3-0.10.1-0.50.7-0.7-0.8
Intermittent access standard deviation0.10.30.9-0.2-0.3-0.40.4-0.00.3-0.90.20.30.9-0.80.80.8
Left kidney weight0.32.45.31.91.81.5-1.32.32.20.6-1.7-1.70.5-1.11.11.4
Right kidney weight0.53.26.82.22.11.9-1.82.42.60.9-1.9-2.00.4-1.11.21.5
Cocaine induced anxiety0.51.32.3-1.5-1.5-1.51.5-1.4-1.1-0.81.51.30.5-0.20.2-0.1
Post-drug Anxiety1.11.21.9-1.3-1.3-1.41.4-1.1-0.5-1.11.31.21.1-0.80.80.7
Baseline Anxiety0.30.51.20.30.20.2-0.30.51.0-0.4-0.2-0.31.0-1.01.01.1
Tail length0.31.53.60.90.70.7-0.71.31.9-0.4-0.6-0.91.2-1.71.71.9
Length with tail0.83.58.71.71.61.5-1.62.23.0-0.1-1.5-1.91.4-2.02.12.4
Length without tail0.21.12.50.90.90.8-0.71.21.6-0.2-0.8-1.00.9-1.11.11.3
Times rat made contact with spout0.10.20.40.20.30.2-0.20.0-0.20.5-0.2-0.1-0.60.6-0.6-0.6
Lifetime Intake0.10.10.3-0.3-0.3-0.30.4-0.2-0.3-0.40.50.40.4-0.10.1-0.0
Liver weight, left0.10.30.50.50.40.5-0.50.60.7-0.3-0.2-0.40.4-0.60.60.6
Liver weight, right0.30.61.3-0.4-0.6-0.30.2-0.30.4-1.10.70.21.2-1.11.11.1
Locomotor activity0.10.10.30.40.40.4-0.40.40.50.3-0.5-0.50.1-0.10.10.2
Locomotor testing distance0.10.20.50.60.50.5-0.50.50.70.4-0.5-0.60.1-0.10.10.2
Locomotor testing rearing0.10.50.9-0.9-0.9-0.90.9-0.9-0.6-0.40.80.80.3-0.10.0-0.0
Locomotion in novel chamber2.63.46.2-2.5-2.5-2.32.2-2.4-2.1-1.42.22.10.8-0.10.1-0.3
Locomotion in novel chamber post-restriction0.10.40.70.80.70.8-0.90.80.70.1-0.6-0.7-0.30.2-0.2-0.0
Fecal boli incidents, locomotor time 10.10.20.6-0.4-0.3-0.30.3-0.6-0.8-0.00.30.4-0.30.6-0.6-0.7
Change in fecal boli incidents, locomotor task0.30.30.70.40.40.3-0.30.70.8-0.1-0.4-0.40.5-0.70.70.8
Time >=10cm from walls, locomotor time 13.13.87.82.12.22.0-1.82.82.50.5-2.0-2.10.8-1.61.71.9
Bouts of movement, locomotor time 10.91.22.30.90.81.0-1.10.30.01.4-0.6-0.6-1.51.5-1.5-1.4
Total resting periods, locomotor time 11.82.13.51.51.41.6-1.60.90.51.9-1.2-1.1-1.81.6-1.6-1.4
Rest time, locomotor task time 10.81.23.60.50.50.6-0.5-0.3-0.61.0-0.5-0.1-1.51.9-1.9-1.8
Distance moved, locomotor task time 10.82.26.30.40.20.1-0.21.11.9-1.2-0.1-0.61.9-2.42.42.5
Vertical activity count, locomotor time 10.21.74.70.60.40.4-0.41.21.9-0.6-0.4-0.81.5-2.02.12.2
Time >=10cm from walls, locomotor time 20.51.32.91.41.41.3-1.21.71.30.6-1.3-1.30.0-0.70.70.8
Bouts of movement, locomotor time 20.93.06.61.41.31.5-1.60.4-0.22.2-1.2-0.8-2.62.4-2.4-2.2
Total resting periods, locomotor time 20.93.57.11.61.61.8-1.80.7-0.12.4-1.4-1.0-2.72.5-2.5-2.3
Rest time, locomotor task time 21.01.63.01.21.11.3-1.30.40.11.6-1.0-0.8-1.61.7-1.7-1.5
Distance moved, locomotor task time 21.21.64.4-0.2-0.4-0.40.30.51.1-1.50.5-0.11.8-2.12.12.1
Vertical activity count, locomotor time 20.20.41.30.1-0.00.0-0.10.30.9-0.4-0.0-0.30.8-1.01.01.1
Light reinforcement 10.00.20.40.40.30.3-0.30.10.10.5-0.2-0.2-0.60.6-0.6-0.5
Light reinforcement 20.92.14.91.11.11.1-1.10.4-0.31.6-0.7-0.5-2.22.2-2.2-2.1
Bone: marrow area2.15.18.7-3.0-2.9-2.92.8-2.4-1.9-2.62.42.31.8-1.11.10.6
Bone: maximum diameter2.55.18.3-2.7-2.6-2.72.6-1.9-1.1-2.92.22.02.5-2.02.01.6
Bone: maximum force0.10.20.4-0.5-0.5-0.50.5-0.4-0.2-0.60.40.30.5-0.30.30.3
Bone: maximum moment0.20.30.7-0.6-0.6-0.70.6-0.4-0.2-0.90.50.40.7-0.50.50.4
Mean time between licks in bursts0.10.41.00.0-0.00.1-0.10.30.6-0.6-0.0-0.20.9-1.01.01.0
Mean num. licks in bursts0.61.74.0-1.0-0.8-1.01.0-0.10.2-1.80.50.52.0-1.91.91.8
Cd content in liver0.80.91.51.21.21.1-1.00.90.71.2-1.0-0.9-0.90.7-0.7-0.5
Co content in liver1.01.12.50.70.80.6-0.61.31.4-0.4-0.9-0.91.0-1.41.41.6
Cu content in liver3.13.78.41.81.71.8-1.70.90.32.9-1.6-1.2-2.72.4-2.4-2.0
Fe content in liver1.21.43.21.11.11.1-1.10.60.21.8-0.9-0.8-1.61.5-1.5-1.3
K content in liver1.01.02.40.60.50.5-0.50.0-0.41.3-0.4-0.2-1.51.5-1.5-1.5
Mg content in liver0.91.02.50.40.40.5-0.5-0.1-0.51.3-0.3-0.1-1.61.6-1.6-1.5
Mn content in liver3.94.411.41.00.91.1-1.1-0.2-0.92.9-0.5-0.3-3.23.4-3.4-3.2
Na content in liver1.31.42.91.11.11.0-0.90.60.11.7-0.8-0.7-1.71.6-1.6-1.4
Rb content in liver0.00.00.10.10.20.1-0.10.1-0.10.2-0.2-0.0-0.40.3-0.3-0.3
Se content in liver12.214.427.74.24.14.1-3.92.71.55.3-3.5-3.0-4.64.0-4.0-3.3
Sr content in liver0.60.50.80.90.90.8-0.80.70.50.8-0.9-0.7-0.60.5-0.5-0.4
Zn content in liver1.41.73.61.21.11.2-1.20.60.21.9-1.0-0.8-1.91.6-1.6-1.4
Bone: minimum diameter3.97.514.6-2.9-2.8-2.92.9-1.7-0.9-3.82.22.03.5-3.03.02.5
Time in familiar zone, hab. session 10.40.41.0-0.8-0.9-0.70.5-0.9-0.7-0.51.00.70.20.0-0.0-0.2
Time in novel zone, hab. session 10.10.20.30.50.50.5-0.60.30.50.5-0.4-0.5-0.10.1-0.1-0.0
Total zone transitions, hab. session 10.10.10.20.20.10.2-0.3-0.0-0.00.5-0.1-0.1-0.50.5-0.5-0.4
Total locomotion distance, hab. session 11.52.13.41.81.71.7-1.71.30.91.8-1.4-1.4-1.51.1-1.1-0.9
Locomotion velocity, hab. session 12.73.86.22.52.42.4-2.42.11.62.3-2.1-2.0-1.71.1-1.1-0.7
Time in familiar zone, hab. session 20.10.10.2-0.3-0.4-0.20.1-0.3-0.1-0.50.40.20.3-0.30.30.2
Time in novel zone, hab. session 20.20.20.30.60.50.6-0.60.40.40.6-0.5-0.5-0.30.2-0.2-0.1
Total zone transitions, hab. session 20.20.20.40.60.60.6-0.60.50.40.4-0.5-0.5-0.30.2-0.2-0.1
Total locomotion distance, hab. session 20.81.11.81.31.31.3-1.31.20.81.0-1.1-1.1-0.80.5-0.5-0.3
Locomotion velocity, hab. session 20.91.21.91.41.41.4-1.31.20.81.2-1.2-1.1-1.00.7-0.7-0.5
Novel to familiar place preference ratio1.92.54.7-1.4-1.3-1.31.4-2.0-2.20.41.31.5-1.31.9-1.9-2.1
Novelty place preference2.12.75.1-1.5-1.4-1.51.5-2.1-2.20.31.41.6-1.21.8-1.8-2.0
Time in novel zone, NPP test2.12.54.9-1.5-1.5-1.41.4-2.1-2.20.21.51.5-1.11.7-1.7-1.9
Total zone transitions, NPP test0.81.22.11.31.31.3-1.31.41.40.5-1.2-1.30.0-0.40.40.6
Total locomotion distance, NPP test2.83.96.72.62.52.5-2.52.31.82.0-2.2-2.2-1.30.7-0.7-0.3
Locomotion velocity, NPP test2.63.66.52.52.52.3-2.22.41.91.8-2.4-2.1-1.10.5-0.5-0.1
Intraocular pressure0.30.50.9-0.5-0.7-0.2-0.1-0.9-0.80.20.90.4-0.90.9-0.9-1.0
Delta distance traveled before/after self-admin1.41.52.7-1.6-1.5-1.61.6-1.4-0.9-1.41.31.40.9-0.50.50.4
Delta ambulatory time before/after self-admin1.32.23.7-1.9-1.8-1.91.9-1.5-0.9-1.71.51.61.3-0.90.90.7
Parametrial fat weight0.92.03.81.61.61.6-1.61.91.90.2-1.5-1.70.4-1.01.01.3
Pavlov. Cond. lever latency0.20.30.7-0.6-0.7-0.50.5-0.6-0.8-0.50.70.60.00.1-0.1-0.3
Pavlov. Cond. magazine entry latency1.72.14.41.71.81.6-1.51.92.10.9-1.8-1.70.3-0.70.71.0
Pavlov. Cond. change in total contacts0.80.82.01.01.00.9-0.81.21.40.3-1.1-1.00.4-0.70.70.9
Pavlov. Cond. index score1.21.52.61.51.51.4-1.41.51.61.1-1.5-1.4-0.2-0.10.10.4
Pavlov. Cond. latency score1.01.22.41.41.41.2-1.21.41.60.9-1.4-1.3-0.0-0.30.30.6
Pavlov. Cond. lever contacts0.60.71.41.11.11.0-0.91.01.20.7-1.0-1.0-0.1-0.10.10.3
Pavlov. Cond. magazine entry number0.50.71.6-0.9-0.9-0.70.6-1.1-1.3-0.31.00.9-0.50.6-0.6-0.9
Pavlov. Cond. intertrial magazine entries0.20.20.40.50.40.5-0.50.10.10.5-0.3-0.3-0.60.6-0.6-0.5
Pavlov. Cond. lever-magazine prob. diff.1.11.32.31.51.51.4-1.31.41.51.0-1.4-1.3-0.2-0.10.10.4
Pavlov. Cond. response bias0.60.71.71.01.00.8-0.71.11.30.5-1.1-0.90.2-0.40.40.7
Pavlov. Cond. lever latency1.62.34.3-2.0-2.0-1.81.8-2.1-1.9-0.81.81.70.20.3-0.3-0.6
Pavlov. Cond. magazine entry latency1.11.62.91.71.61.5-1.51.71.60.7-1.4-1.4-0.2-0.30.30.6
Pavlov. Cond. change in total contacts0.41.02.11.21.21.1-1.11.51.40.1-1.2-1.10.2-0.60.60.8
Pavlov. Cond. index score1.82.85.42.22.22.0-2.02.32.10.9-2.0-1.9-0.3-0.40.40.8
Pavlov. Cond. latency score1.62.64.92.12.12.0-1.92.22.00.9-2.0-1.8-0.4-0.30.30.6
Pavlov. Cond. lever contacts1.52.24.11.91.91.8-1.72.01.80.7-1.8-1.7-0.1-0.40.40.7
Pavlov. Cond. magazine entry number3.54.68.2-2.8-2.7-2.62.6-2.9-2.6-1.42.52.40.50.3-0.3-0.8
Pavlov. Cond. intertrial magazine entries1.02.13.7-1.9-1.8-1.81.8-1.9-1.8-0.91.61.60.20.3-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.1.92.95.42.22.22.1-2.02.32.10.9-2.0-1.9-0.3-0.40.40.7
Pavlov. Cond. response bias2.02.85.22.12.12.0-2.02.32.20.8-2.0-1.9-0.1-0.60.60.9
Time in closed arm before self-admin0.30.51.4-0.4-0.3-0.30.4-0.5-1.20.20.10.6-0.71.0-1.0-1.1
Time in closed arm after self-admin0.10.10.2-0.2-0.1-0.20.3-0.2-0.5-0.0-0.20.3-0.30.4-0.3-0.5
Time in open arm before self-admin0.30.40.9-0.7-0.8-0.70.7-0.9-0.7-0.20.70.6-0.20.5-0.5-0.6
Time in open arm after self-admin0.10.20.4-0.4-0.4-0.30.3-0.6-0.50.20.50.3-0.10.4-0.4-0.4
Bone: periosteal estimation1.22.95.4-2.0-1.9-2.02.0-1.3-0.8-2.31.51.41.9-1.61.61.3
Bone: periosteal perimeter1.52.95.5-1.9-1.8-2.02.0-1.2-0.8-2.31.51.42.0-1.61.61.3
Bone: post-yield work0.30.50.8-0.9-0.9-0.90.9-0.8-0.5-0.80.70.70.6-0.40.40.2
Progressive ratio test 1 active lever presses0.00.10.20.20.20.2-0.20.0-0.10.10.10.1-0.20.5-0.5-0.5
Progressive ratio test 1 breakpoint0.10.10.20.40.30.3-0.30.2-0.00.2-0.0-0.0-0.20.5-0.4-0.4
Progressive ratio test 1 inactive lever presses0.10.10.3-0.3-0.2-0.30.4-0.3-0.5-0.60.30.50.10.2-0.2-0.3
Progressive ratio test 2 active lever presses0.10.20.70.0-0.00.1-0.1-0.2-0.50.40.20.2-0.60.8-0.8-0.8
Progressive ratio test 2 breakpoint0.20.20.60.10.00.1-0.1-0.2-0.40.50.20.1-0.60.7-0.7-0.8
Progressive ratio test 2 inactive lever presses0.20.51.5-0.3-0.3-0.20.3-0.6-1.00.20.70.6-0.61.1-1.1-1.2
Incentive Sensitization - Responses0.00.10.30.00.10.1-0.1-0.1-0.30.4-0.0-0.1-0.60.5-0.5-0.5
Incentive Sensitization - Breakpoint0.10.10.40.20.20.3-0.30.1-0.10.5-0.2-0.3-0.60.4-0.4-0.4
Sum of active levers in priming session hrs 5-60.10.10.20.20.10.2-0.2-0.20.10.0-0.2-0.1-0.40.5-0.5-0.3
Progressive ratio0.20.40.8-0.6-0.6-0.60.5-0.30.0-0.90.50.40.9-0.90.90.8
Food seeking constrained by brief footshock0.81.02.11.41.41.3-1.11.41.30.2-1.3-1.0-0.2-0.20.20.4
Seeking ratio, punishment vs. effort0.71.62.91.71.71.6-1.51.41.11.2-1.5-1.4-0.90.6-0.6-0.4
Retroperitoneal fat weight0.10.20.70.10.00.0-0.10.30.6-0.50.1-0.20.6-0.80.80.8
Reaction time number correct0.82.74.7-2.2-2.2-2.01.9-2.1-1.9-1.41.91.90.60.0-0.0-0.4
Reaction time mean minus median0.21.23.40.40.30.3-0.40.91.5-0.7-0.2-0.71.3-1.71.71.8
Reaction time mean minus median AUC0.10.72.10.1-0.1-0.0-0.10.41.0-0.70.1-0.31.1-1.41.41.5
Reaction time num false alarms0.20.31.10.0-0.00.1-0.10.20.8-0.5-0.1-0.20.7-0.90.91.0
Reaction time num false alarms AUC0.30.61.90.10.10.1-0.20.41.0-0.6-0.2-0.31.0-1.31.31.4
Reaction time trials correct on left0.82.74.7-2.2-2.2-2.01.9-2.1-1.9-1.41.91.90.60.0-0.0-0.4
Reaction time trials on left0.72.54.5-2.1-2.1-1.91.9-2.0-1.8-1.41.81.80.6-0.00.0-0.3
Reaction time mean0.71.53.21.31.31.3-1.31.61.80.4-1.1-1.40.4-1.01.01.2
Reaction time mean AUC0.61.53.11.41.31.3-1.31.61.80.5-1.2-1.40.2-0.80.81.1
Median of all reaction times0.60.91.61.11.11.1-1.21.21.30.6-1.0-1.2-0.1-0.40.40.6
Reaction time omissions0.40.71.9-0.00.1-0.00.10.60.7-0.7-0.5-0.41.2-1.31.31.4
Reaction time false alarm rate0.91.23.01.11.01.0-1.01.31.70.1-1.0-1.10.6-1.11.11.3
Reaction time premature initiation rate1.82.96.31.81.71.5-1.42.32.50.1-1.5-1.61.0-1.71.72.0
Reaction time premature initiations0.51.43.30.80.70.5-0.51.31.6-0.6-0.6-0.71.3-1.71.71.8
Std. dev. reaction times0.72.35.60.90.80.7-0.81.52.1-0.7-0.8-1.21.6-2.22.22.4
Reaction time trials completed0.72.54.5-2.1-2.1-1.91.9-2.0-1.8-1.41.81.80.6-0.00.0-0.3
Reaction time trials AUC0.72.64.5-2.1-2.1-1.91.8-2.1-1.9-1.31.81.90.50.1-0.1-0.4
Run reversals in cocaine runway, females0.70.82.3-0.00.00.1-0.0-0.3-1.11.10.00.1-1.31.4-1.4-1.5
Run reversals in cocaine runway, males3.03.35.72.42.22.3-2.42.22.01.6-2.0-2.1-1.00.2-0.20.2
Latency to leave start box in cocaine runway2.63.55.5-2.4-2.3-2.32.3-2.0-1.5-2.22.22.11.5-1.01.00.6
Latency to leave start box in cocaine runway, F3.74.77.6-2.7-2.7-2.82.7-2.4-1.9-2.52.52.41.4-0.80.80.4
Latency to leave start box in cocaine runway, M0.50.50.7-0.8-0.7-0.70.8-0.7-0.5-0.70.80.70.9-0.50.50.4
Std. dev. time between licks in bursts0.20.30.70.60.50.7-0.70.30.10.6-0.4-0.4-0.80.7-0.7-0.6
Total sessions with >9 infusions0.10.10.3-0.2-0.1-0.20.3-0.3-0.6-0.20.30.4-0.10.4-0.4-0.5
Short access day 1 total inactive lever presses1.22.45.7-1.7-1.5-1.71.8-1.8-2.4-1.01.51.90.00.9-0.9-1.3
Short access day 10 total inactive lever presses0.00.20.40.60.60.4-0.30.60.7-0.0-0.7-0.40.3-0.30.30.4
Short access day 1 total infusions0.40.82.20.60.70.6-0.40.2-0.70.8-0.4-0.1-1.21.5-1.5-1.5
Short access day 10 total infusions0.20.30.60.70.80.7-0.70.60.30.4-0.5-0.4-0.30.4-0.4-0.3
Short access total infusions0.10.10.40.10.10.00.1-0.1-0.5-0.00.20.3-0.20.6-0.6-0.6
Short access day 1 locomotion1.22.14.1-1.5-1.5-1.51.5-1.9-2.0-0.61.51.7-0.41.1-1.1-1.4
Short access day 10 total locomotion0.10.20.40.40.50.4-0.30.3-0.10.4-0.4-0.2-0.50.6-0.6-0.6
Short access total locomotion0.20.30.7-0.5-0.4-0.40.5-0.7-0.8-0.30.60.7-0.20.7-0.7-0.8
One hour access (0.3 mA shock)0.30.30.6-0.7-0.7-0.70.7-0.6-0.7-0.60.70.70.2-0.10.1-0.1
Compulsive drug intake0.71.12.0-1.1-1.0-1.11.2-0.5-0.3-1.40.50.61.3-1.31.31.2
One hour access (shock baseline)0.00.00.10.1-0.0-0.0-0.00.00.1-0.00.30.10.1-0.00.0-0.0
Social response proportion2.12.75.2-2.1-2.0-1.91.8-2.2-2.3-0.91.81.9-0.10.6-0.6-1.0
Social responses0.70.91.7-1.2-1.3-1.11.0-1.1-0.8-1.11.11.00.8-0.60.60.4
Social time0.10.10.20.10.20.10.00.20.3-0.1-0.4-0.20.5-0.40.40.5
Soleus weight0.72.13.8-1.9-1.9-1.91.8-1.7-1.5-1.51.61.60.9-0.40.40.1
Bone: stiffness0.20.30.9-0.3-0.3-0.30.2-0.10.4-0.80.20.01.0-0.90.90.9
Tibialis anterior weight0.41.22.4-1.6-1.4-1.41.4-1.4-1.0-0.81.21.20.8-0.30.30.2
Time to tail flick, vehicle, before self-admin0.81.02.7-0.2-0.3-0.10.0-0.8-1.00.60.40.4-1.31.6-1.6-1.7
Time to tail flick, vehicle, after self-admin0.20.40.7-0.8-0.7-0.80.8-0.9-0.6-0.70.60.70.30.1-0.1-0.1
Time to tail flick, test, before self-admin0.20.20.4-0.4-0.5-0.50.5-0.7-0.3-0.50.40.5-0.10.2-0.3-0.2
Time to tail flick, test, after self-admin0.70.71.6-0.5-0.6-0.40.4-0.9-1.10.10.70.7-0.91.2-1.2-1.3
Delta time to tail flick, vehicle, before/after SA0.10.10.3-0.2-0.1-0.20.3-0.00.1-0.3-0.10.10.6-0.40.40.4
Delta time to tail flick, test, before/after SA0.20.30.70.10.20.3-0.3-0.1-0.50.60.00.0-0.80.8-0.8-0.9
Tibia length0.20.40.90.50.50.3-0.30.80.9-0.3-0.4-0.50.6-0.90.90.9
Ambulatory time before self-admin0.10.30.8-0.4-0.5-0.30.2-0.7-0.90.10.40.4-0.40.7-0.7-0.8
Ambulatory time after self-admin1.11.83.3-1.7-1.7-1.61.5-1.8-1.7-0.81.51.60.10.5-0.5-0.8
Bone: tissue strength0.20.20.5-0.4-0.3-0.40.4-0.1-0.1-0.70.20.20.6-0.50.50.5
Total heroin consumption0.30.40.70.70.70.8-0.90.40.80.7-0.7-0.7-0.20.2-0.20.1
Bone: trabecular number0.61.02.0-1.3-1.2-1.31.4-1.2-1.3-0.91.01.20.30.1-0.1-0.4
Bone: trabecular spacing0.81.22.71.11.01.2-1.31.31.60.1-0.9-1.20.6-1.01.01.2
Bone: trabecular thickness0.70.91.6-1.1-1.0-1.11.2-0.6-0.5-1.30.70.71.2-1.01.00.8
Bone: trabecular tissue density0.81.32.4-1.5-1.5-1.41.3-1.4-1.1-1.01.51.30.5-0.30.30.0
Water consumed over 24 hours0.20.41.00.50.40.4-0.40.1-0.20.7-0.3-0.2-1.01.0-1.0-0.9
Number of responses in last shaping day0.10.10.2-0.3-0.3-0.40.4-0.4-0.3-0.40.40.40.20.1-0.1-0.1