Hub : Genes

LOC100911718

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver alternative polyA XM_063280359.1 0.21 0 0.0e+00 0.37 0.41 0.42 0.42 1.0e-42 1.9e-49 1.0e-50 9.7e-51
2 Liver alternative polyA XM_063280353.1 0.22 0 0.0e+00 0.36 0.41 0.42 0.42 4.9e-42 1.1e-48 8.1e-50 7.9e-50
3 Liver intron excision ratio chr1_247013856_247014589 0.15 0.02 0.0e+00 0.49 0.52 0.52 0.52 1.9e-62 1.6e-66 3.1e-66 5.7e-67
4 Liver intron excision ratio chr1_247013856_247015572 0.15 0.01 0.0e+00 0.53 0.54 0.54 0.54 1.9e-69 2.9e-70 2.5e-71 2.6e-71
5 Liver isoform ratio XM_063280359.1 0.13 0.02 0.0e+00 0.33 0.36 0.36 0.36 4.6e-37 6.3e-41 7.1e-42 1.3e-41
6 Liver isoform ratio XR_010061283.1 0.13 0.02 0.0e+00 0.21 0.26 0.25 0.27 1.6e-22 9.8e-29 6.2e-28 1.2e-29
7 Liver mRNA stability LOC100911718 0.2 0.02 8.8e-05 0.03 0.03 0.02 0.03 1.8e-04 5.5e-04 9.0e-04 2.0e-04
8 Liver isoform ratio XM_063280352.1 0.18 0.02 0.0e+00 0.48 0.52 0.52 0.49 7.2e-60 5.6e-67 2.4e-67 1.1e-61
9 Liver isoform ratio XR_010061284.1 0.11 0.03 0.0e+00 0.21 0.23 0.24 0.23 1.0e-22 4.0e-25 8.9e-27 1.9e-25
10 Liver isoform ratio XM_063280354.1 0.09 0.01 0.0e+00 0.36 0.36 0.35 0.34 1.7e-41 5.9e-42 3.0e-40 5.3e-39
11 Liver intron excision ratio chr1_247037788_247053570 0.13 0.01 0.0e+00 0.18 0.32 0.33 0.33 2.1e-19 4.6e-36 2.1e-37 1.3e-37
12 Liver intron excision ratio chr1_247018300_247053570 0.13 0.01 0.0e+00 0.18 0.32 0.33 0.33 1.8e-19 3.8e-36 1.7e-37 8.1e-38
13 Liver gene expression LOC100911718 0.14 0.01 0.0e+00 0.38 0.48 0.49 0.49 3.3e-44 2.4e-59 5.9e-62 2.0e-62

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13
Bone: apparent density1.12.03.31.8-1.8-1.81.81.7-1.71.2-1.5-1.60.60.0-0.1-0.4
Area under the delay curve1.11.33.3-0.60.60.7-0.70.2-0.4-1.30.30.3-1.81.8-1.8-1.7
BMI with tail0.82.95.12.1-2.2-2.12.02.2-2.31.2-1.9-2.00.20.4-0.4-0.8
BMI without tail0.10.20.40.5-0.5-0.60.50.5-0.50.4-0.6-0.60.00.0-0.0-0.1
Body weight0.31.22.80.5-0.5-0.60.50.10.61.5-0.6-0.21.7-1.71.71.6
Weight adjusted by age0.81.22.31.3-1.3-1.21.21.5-1.50.4-1.1-1.2-0.30.7-0.7-0.9
Bone surface1.42.54.42.1-2.1-2.12.11.7-1.51.7-1.5-1.71.2-0.60.60.2
Bone volume1.32.33.71.9-1.9-1.91.91.4-1.21.9-1.5-1.51.4-0.90.90.6
Breakpoint value in progressive ratio session0.91.11.9-1.41.41.3-1.3-1.11.1-0.91.31.1-0.60.5-0.5-0.1
Number of licking bursts1.32.15.4-0.80.80.8-0.80.1-0.6-1.90.40.2-2.32.3-2.3-2.2
Context. condit. distance diff. score0.30.30.60.7-0.7-0.70.70.5-0.50.8-0.6-0.50.5-0.20.20.1
Locomotion velocity, session 13.53.87.8-1.81.71.6-1.6-0.8-0.0-2.71.41.0-2.82.6-2.6-2.4
Locomotion distance, session 11.31.63.3-1.41.41.3-1.4-1.00.5-1.81.31.1-1.51.3-1.2-1.0
Locomotion velocity, session 21.11.22.7-0.90.90.7-0.7-0.4-0.2-1.60.90.5-1.61.6-1.6-1.5
Locomotion distance, session 20.40.61.3-0.70.60.6-0.6-0.3-0.1-1.00.60.4-1.11.1-1.1-1.0
Locomotion velocity, session 30.40.50.9-0.60.70.5-0.5-1.00.9-0.10.80.70.4-0.70.70.8
Locomotion distance, session 32.02.24.3-1.11.11.0-1.1-1.82.10.61.21.31.4-1.91.92.1
Stereotopy head waving bouts, day 30.10.10.2-0.30.20.2-0.3-0.10.1-0.40.10.2-0.30.3-0.3-0.2
Stereotopy head waving duration, day 30.30.31.0-0.20.20.2-0.20.2-0.3-0.80.0-0.0-0.91.0-1.0-0.9
Locomotion velocity, session 70.60.61.50.6-0.6-0.40.40.30.11.2-0.7-0.31.2-1.11.11.0
Locomotion distance, session 70.91.12.60.9-0.9-0.80.80.4-0.11.6-0.7-0.51.5-1.41.41.3
Stereotopy head waving bouts, day 71.61.83.1-1.61.61.6-1.6-1.00.8-1.81.11.2-1.51.2-1.2-0.9
Stereotopy head waving duration, day 70.81.01.6-1.31.31.2-1.2-0.90.7-1.30.91.0-1.00.7-0.7-0.5
Locomotion velocity, session 80.10.10.1-0.30.30.3-0.3-0.30.1-0.20.40.2-0.20.2-0.2-0.1
Locomotion distance, session 80.20.20.70.2-0.2-0.20.20.4-0.7-0.1-0.2-0.3-0.50.7-0.7-0.8
Degree of sensitization distance1.31.42.81.1-1.1-0.90.91.6-1.7-0.2-1.2-1.1-0.81.3-1.3-1.5
Degree of sensitization stereotypy2.12.33.5-1.91.91.9-1.9-1.31.0-1.81.31.5-1.51.1-1.1-0.8
Conditioned locomotion1.11.22.01.4-1.4-1.31.31.0-0.71.4-1.0-1.01.2-0.90.90.7
Cocaine response after cond. corrected0.10.10.3-0.10.10.1-0.10.1-0.2-0.30.0-0.0-0.50.5-0.5-0.5
Cocaine response after cond. not corrected0.30.30.5-0.70.70.7-0.7-0.70.5-0.50.70.6-0.40.2-0.2-0.1
Cocaine response before conditioning1.21.42.5-1.61.61.4-1.4-1.51.4-1.01.51.3-0.40.0-0.00.2
Saline control response1.62.13.6-1.91.91.7-1.7-1.71.2-1.61.81.5-1.00.7-0.7-0.4
Bone: connectivity density2.84.47.42.7-2.7-2.72.72.6-2.51.7-2.2-2.40.80.0-0.0-0.5
Bone: cortical apparent density0.91.23.0-0.70.60.6-0.5-0.0-0.5-1.40.40.2-1.71.7-1.7-1.7
Bone: cortical area1.11.74.80.2-0.1-0.20.1-0.71.21.50.10.32.0-2.22.22.2
Bone: cortical porosity1.61.73.21.0-1.0-0.90.91.6-1.8-0.5-1.2-1.2-1.21.6-1.6-1.8
Bone: cortical porosity0.70.81.40.8-0.8-0.70.71.1-1.2-0.2-0.9-0.8-0.70.9-0.9-1.1
Bone: cortical thickness1.93.15.9-2.12.12.0-2.0-2.42.4-0.71.92.00.3-1.01.01.4
Bone: cortical thickness2.53.05.1-2.32.22.2-2.1-1.81.5-1.91.91.8-1.30.8-0.8-0.4
Bone: cortical tissue density1.01.43.7-0.50.50.5-0.40.2-0.7-1.40.20.0-1.81.9-1.9-1.9
Condit. Reinf. active minus inactive responses0.20.20.3-0.50.60.4-0.5-0.50.6-0.60.60.5-0.20.2-0.2-0.0
Condit. Reinf. active-inactive response ratio0.00.00.1-0.10.1-0.0-0.0-0.20.4-0.10.20.10.1-0.10.10.2
Condit. Reinf. active responses0.10.10.3-0.50.50.3-0.4-0.50.6-0.40.50.4-0.1-0.00.00.1
Condit. Reinf. inactive responses0.10.10.3-0.30.30.3-0.3-0.20.0-0.60.30.2-0.50.4-0.4-0.4
Incentive salience index mean0.50.61.3-1.01.00.8-0.9-1.11.2-0.51.00.9-0.0-0.20.20.4
Condit. Reinf. lever presses0.60.91.6-1.21.31.1-1.2-1.21.2-0.61.11.1-0.3-0.10.10.3
Condit. Reinf. active minus inactive responses1.62.13.61.9-1.9-1.81.81.5-1.21.7-1.4-1.51.2-0.70.70.5
Condit. Reinf. active-inactive response ratio1.31.52.61.6-1.6-1.61.51.5-1.41.1-1.3-1.40.40.0-0.0-0.3
Condit. Reinf. active responses0.81.12.70.7-0.6-0.60.70.00.31.5-0.3-0.31.6-1.61.61.5
Condit. Reinf. inactive responses2.22.95.6-1.51.51.4-1.4-2.12.40.21.61.61.3-1.91.92.1
Condit. Reinf. lever presses0.50.81.5-1.01.11.0-0.9-1.21.1-0.21.11.00.2-0.40.40.6
Condit. Reinf. lever reinforcers received0.40.61.40.3-0.3-0.30.3-0.20.41.00.1-0.01.2-1.21.21.2
Conditioned reinforcement - actives0.30.51.0-1.01.00.9-1.0-0.80.9-0.60.80.8-0.1-0.10.10.2
Conditioned reinforcement - inactives0.50.81.3-1.11.11.1-1.1-0.70.7-1.10.80.8-0.80.6-0.6-0.4
Conditioned locomotion0.40.61.0-0.91.00.9-0.9-1.00.9-0.71.00.8-0.0-0.10.10.3
Patch foraging indifference point 0 sec0.61.12.3-1.11.11.0-1.1-1.31.5-0.20.91.10.4-0.80.81.1
Patch foraging indifference point AUC3.85.48.5-2.92.82.9-2.9-2.31.6-2.72.72.3-2.11.5-1.5-1.0
Delay disc. indifference point, 0s delay1.71.94.01.4-1.5-1.41.31.8-2.00.7-1.6-1.5-0.61.0-1.0-1.3
Delay disc. indifference point, 16s delay0.70.81.6-0.90.90.9-0.9-0.40.1-1.10.50.6-1.31.1-1.1-1.0
Delay disc. indifference point, 2s delay1.41.63.10.9-1.0-0.90.81.8-1.5-0.2-1.2-1.1-1.21.5-1.5-1.7
Delay disc. indifference point, 24s delay2.22.53.7-1.91.91.9-1.9-1.21.0-1.81.61.4-1.71.4-1.4-1.0
Delay disc. indifference point, 4s delay0.60.72.0-0.30.20.3-0.40.4-0.4-0.7-0.00.1-1.41.4-1.4-1.4
Delay disc. indifference point, 8s delay2.52.95.8-1.61.51.7-1.6-0.7-0.0-2.11.11.0-2.42.3-2.3-2.1
Indifference point function ln k2.34.16.22.4-2.4-2.52.51.9-1.22.4-2.3-2.01.9-1.51.51.1
Indifference point function log k2.34.16.22.4-2.4-2.52.51.9-1.22.4-2.3-2.01.9-1.51.51.1
Patch foraging total patch changes 0 sec0.61.22.7-1.11.21.0-1.1-1.41.6-0.10.91.10.6-1.01.01.2
Patch foraging total patch changes 12 sec3.34.36.8-2.62.62.6-2.6-2.11.6-2.42.42.1-1.61.1-1.1-0.7
Patch foraging total patch changes 18 sec1.11.72.9-1.51.51.5-1.5-1.10.6-1.71.41.2-1.41.1-1.1-0.9
Patch foraging total patch changes 24 sec0.91.62.7-1.51.51.5-1.5-1.61.6-0.81.51.50.0-0.40.40.7
Patch foraging total patch changes 6 sec4.36.511.2-3.33.33.4-3.3-2.92.4-2.52.92.8-1.50.7-0.7-0.2
Patch foraging time to switch 0 sec0.40.82.3-0.30.30.3-0.30.2-0.6-1.30.20.1-1.31.5-1.5-1.5
Patch foraging water rate 0 sec0.40.82.10.7-0.7-0.80.80.30.11.4-0.7-0.61.2-1.21.21.1
Patch foraging water rate 12 sec0.20.41.20.0-0.0-0.20.2-0.30.60.80.00.00.9-1.11.11.1
Patch foraging water rate 18 sec0.30.41.10.1-0.1-0.10.1-0.30.50.70.10.11.0-1.01.01.1
Patch foraging water rate 24 sec0.20.30.70.4-0.4-0.50.40.2-0.00.8-0.4-0.30.7-0.70.70.6
Patch foraging water rate 6 sec0.00.00.1-0.10.1-0.00.1-0.10.20.1-0.0-0.00.1-0.20.20.2
Seeking ratio, delayed vs. immediate footshock0.60.71.8-0.50.50.5-0.4-0.91.10.20.40.71.1-1.21.21.3
Distance traveled before self-admin0.20.30.70.4-0.5-0.30.40.6-0.8-0.2-0.4-0.3-0.30.6-0.7-0.7
Distance traveled after self-admin0.81.02.01.3-1.3-1.21.21.4-1.20.6-1.0-1.20.20.3-0.3-0.4
Extensor digitorum longus weight0.20.81.31.2-1.1-1.11.11.0-0.70.8-0.8-0.90.8-0.40.40.3
Bone: elastic displacement0.91.12.31.1-1.1-1.11.21.2-1.50.2-1.1-1.2-0.50.8-0.8-1.1
Bone: elastic work0.40.61.30.8-0.8-0.90.90.9-1.10.4-0.8-0.8-0.30.5-0.5-0.7
Bone: endosteal estimation2.35.18.72.9-2.9-2.82.72.4-1.82.6-2.4-2.31.8-1.21.20.7
Bone: endosteal perimeter2.55.38.93.0-3.0-2.92.92.4-1.82.7-2.4-2.31.9-1.21.20.8
Epididymis fat weight1.03.35.52.1-2.1-2.32.21.7-1.12.4-2.1-1.81.7-1.11.10.8
Delta time in closed arm before/after self-admin0.40.41.2-0.50.50.4-0.4-0.51.1-0.00.40.60.4-0.70.70.8
Delta time in open arm before/after self-admin0.70.71.51.0-1.0-0.81.01.1-1.20.5-0.9-0.90.10.3-0.3-0.5
Diff in mean of infusions in LGA sessions0.20.30.60.6-0.6-0.50.60.5-0.10.2-0.3-0.40.8-0.50.50.5
Delay discount exponential model param1.11.23.20.8-0.7-0.80.8-0.10.21.3-0.4-0.41.8-1.71.71.6
Extinction: sum of active levers before priming0.40.41.2-0.40.40.4-0.4-0.51.1-0.10.40.50.7-0.80.81.0
Active lever presses in extinction session 62.22.24.81.4-1.4-1.31.31.9-2.20.2-1.1-1.6-0.91.6-1.6-1.8
Bone: final force0.20.40.9-0.30.30.4-0.4-0.60.80.40.20.50.7-0.90.91.0
Bone: final moment0.30.41.2-0.10.10.2-0.2-0.40.70.70.00.30.9-1.11.11.1
Food consumed during 24 hour testing period1.01.42.6-1.51.51.4-1.4-1.61.4-0.91.51.3-0.2-0.10.10.4
Glucose0.40.71.9-0.20.20.2-0.2-0.70.90.50.40.41.1-1.31.31.4
Heart weight0.91.44.00.2-0.1-0.20.2-0.51.11.2-0.10.21.8-2.02.02.0
Delay discount hyperbolic model param0.91.02.60.5-0.4-0.50.5-0.30.41.0-0.1-0.11.6-1.61.61.5
Intermittent access intake day 1-15 change0.51.01.71.3-1.3-1.31.20.9-0.81.0-1.0-1.10.8-0.60.50.4
Intermittent access intake escalation0.71.52.51.6-1.6-1.61.51.2-1.01.3-1.4-1.31.0-0.70.70.5
Intermittent access intake escalation 21.11.32.21.5-1.5-1.51.41.3-1.01.2-1.3-1.20.6-0.40.40.2
Intermitt. access day 1 inactive lever presses0.10.30.90.5-0.5-0.60.60.4-1.00.3-0.3-0.70.00.5-0.5-0.6
Intermitt. access day 15 inactive lever presses0.20.30.90.4-0.4-0.50.50.1-0.10.8-0.3-0.41.0-0.70.70.6
Intermitt. access escalation Index0.30.40.80.7-0.7-0.70.70.4-0.30.9-0.5-0.50.7-0.60.60.5
Intermittent access day 1 total infusions0.00.10.3-0.20.20.2-0.20.0-0.2-0.1-0.1-0.1-0.20.5-0.4-0.5
Intermittent access day 15 total infusions0.71.02.30.9-0.9-0.90.90.50.11.3-1.0-0.71.5-1.31.31.2
Intermittent access terminal intake (last 3 days)0.20.30.60.4-0.4-0.50.40.30.00.6-0.6-0.40.8-0.60.60.6
Intermittent access total infusions0.10.10.40.2-0.2-0.20.20.1-0.00.5-0.4-0.30.6-0.40.40.3
Intermittent access day 1 locomotion0.30.40.90.6-0.6-0.70.70.4-0.20.9-0.7-0.61.0-0.60.70.5
Intermittent access day 15 total locomotion0.30.50.7-0.80.80.7-0.8-0.50.2-0.80.70.5-0.80.8-0.8-0.7
Intermittent access total locomotion0.20.20.6-0.00.00.1-0.10.2-0.5-0.30.1-0.1-0.50.7-0.7-0.8
Intermittent access standard deviation0.20.30.90.3-0.2-0.40.30.00.30.9-0.2-0.30.9-0.80.80.8
Left kidney weight0.52.45.3-1.81.91.4-1.4-2.32.2-0.61.71.70.5-1.11.11.4
Right kidney weight0.73.36.8-2.12.21.9-1.9-2.42.6-0.91.92.00.4-1.11.21.5
Cocaine induced anxiety0.91.32.31.5-1.5-1.51.41.4-1.10.8-1.5-1.30.5-0.20.2-0.0
Post-drug Anxiety1.11.21.91.3-1.3-1.41.31.1-0.51.1-1.3-1.21.1-0.80.80.7
Baseline Anxiety0.40.51.2-0.20.30.2-0.2-0.51.00.40.20.31.0-1.01.01.1
Tail length0.41.53.6-0.80.90.7-0.7-1.31.90.40.60.91.2-1.71.71.9
Length with tail0.83.68.7-1.71.71.5-1.6-2.23.00.11.51.91.4-2.02.12.4
Length without tail0.31.12.5-0.90.90.8-0.8-1.21.60.20.81.00.9-1.11.11.3
Times rat made contact with spout0.10.20.4-0.30.20.2-0.2-0.0-0.2-0.50.20.1-0.60.6-0.6-0.6
Lifetime Intake0.10.10.30.3-0.3-0.30.30.2-0.30.4-0.5-0.40.4-0.10.1-0.0
Liver weight, left0.20.20.5-0.50.50.5-0.4-0.60.70.30.20.40.4-0.60.60.6
Liver weight, right0.30.61.30.4-0.4-0.30.30.30.41.1-0.7-0.21.2-1.11.11.1
Locomotor activity0.10.10.3-0.40.40.4-0.4-0.40.5-0.30.50.50.1-0.10.10.2
Locomotor testing distance0.10.20.5-0.60.60.5-0.5-0.50.7-0.40.50.60.1-0.10.10.2
Locomotor testing rearing0.20.50.90.9-0.9-0.90.90.9-0.60.4-0.8-0.80.3-0.10.0-0.0
Locomotion in novel chamber2.73.46.12.5-2.5-2.32.32.4-2.11.4-2.2-2.10.8-0.10.1-0.3
Locomotion in novel chamber post-restriction0.20.40.7-0.90.80.8-0.8-0.80.7-0.10.60.7-0.30.2-0.2-0.0
Fecal boli incidents, locomotor time 10.20.20.60.3-0.4-0.30.30.6-0.80.0-0.3-0.4-0.30.6-0.6-0.7
Change in fecal boli incidents, locomotor task0.30.30.7-0.40.40.3-0.3-0.70.80.10.40.40.5-0.70.70.8
Time >=10cm from walls, locomotor time 13.53.87.8-2.12.11.9-1.8-2.82.5-0.52.02.10.8-1.61.71.9
Bouts of movement, locomotor time 11.01.22.3-1.00.91.0-1.1-0.30.0-1.40.60.6-1.51.5-1.5-1.4
Total resting periods, locomotor time 11.92.13.5-1.61.51.6-1.6-0.90.5-1.91.21.1-1.81.6-1.6-1.4
Rest time, locomotor task time 11.01.23.6-0.50.50.6-0.60.3-0.6-1.00.50.1-1.51.9-1.9-1.8
Distance moved, locomotor task time 11.52.26.3-0.30.40.1-0.2-1.11.91.20.10.61.9-2.42.42.5
Vertical activity count, locomotor time 10.71.74.7-0.50.60.4-0.4-1.21.90.60.40.81.5-2.02.12.2
Time >=10cm from walls, locomotor time 20.91.32.9-1.41.41.3-1.2-1.71.3-0.61.31.30.0-0.70.70.8
Bouts of movement, locomotor time 21.93.06.6-1.51.41.5-1.5-0.4-0.2-2.21.20.8-2.62.4-2.4-2.2
Total resting periods, locomotor time 22.03.57.1-1.71.61.8-1.7-0.7-0.1-2.41.41.0-2.72.5-2.5-2.3
Rest time, locomotor task time 21.31.63.0-1.21.21.3-1.2-0.40.1-1.61.00.8-1.61.7-1.7-1.5
Distance moved, locomotor task time 21.31.64.40.2-0.2-0.40.3-0.51.11.5-0.50.11.8-2.12.12.1
Vertical activity count, locomotor time 20.30.41.3-0.10.10.0-0.1-0.30.90.40.00.30.8-1.01.01.1
Light reinforcement 10.10.20.4-0.40.40.3-0.3-0.10.1-0.50.20.2-0.60.6-0.6-0.5
Light reinforcement 21.42.14.9-1.21.11.1-1.0-0.4-0.3-1.60.70.5-2.22.2-2.2-2.1
Bone: marrow area2.45.18.83.0-3.0-2.92.82.4-1.92.6-2.4-2.31.8-1.11.10.6
Bone: maximum diameter2.85.28.32.7-2.7-2.72.61.9-1.12.9-2.2-2.02.5-2.02.01.6
Bone: maximum force0.10.20.40.5-0.5-0.50.40.4-0.20.6-0.4-0.30.5-0.30.30.3
Bone: maximum moment0.20.30.70.7-0.6-0.70.60.4-0.20.9-0.5-0.40.7-0.50.50.4
Mean time between licks in bursts0.20.41.00.00.00.1-0.1-0.30.60.60.00.20.9-1.01.01.0
Mean num. licks in bursts1.11.74.01.0-1.0-1.01.00.10.21.8-0.5-0.52.0-1.91.91.8
Cd content in liver0.80.91.5-1.21.21.1-1.0-0.90.7-1.21.00.9-0.90.7-0.7-0.5
Co content in liver1.01.12.5-0.70.70.6-0.5-1.31.40.40.90.91.0-1.41.41.6
Cu content in liver3.23.78.4-1.81.81.8-1.8-0.90.3-2.91.61.2-2.72.4-2.4-2.0
Fe content in liver1.21.43.2-1.21.11.1-1.1-0.60.2-1.80.90.8-1.61.5-1.5-1.3
K content in liver1.01.02.4-0.60.60.5-0.5-0.0-0.4-1.30.40.2-1.51.5-1.5-1.5
Mg content in liver0.91.02.5-0.50.40.5-0.40.1-0.5-1.30.30.1-1.61.6-1.6-1.5
Mn content in liver4.04.511.4-1.11.01.1-1.00.2-0.9-2.90.50.3-3.23.4-3.4-3.2
Na content in liver1.41.52.9-1.21.11.0-1.0-0.60.1-1.70.80.7-1.71.6-1.6-1.4
Rb content in liver0.00.00.1-0.10.10.1-0.1-0.1-0.1-0.20.20.0-0.40.3-0.3-0.3
Se content in liver12.314.627.7-4.24.24.1-4.1-2.71.5-5.33.53.0-4.64.0-4.0-3.3
Sr content in liver0.60.50.8-0.90.90.8-0.8-0.70.5-0.80.90.7-0.60.5-0.5-0.4
Zn content in liver1.51.73.6-1.21.21.2-1.1-0.60.2-1.91.00.8-1.91.6-1.6-1.4
Bone: minimum diameter4.17.614.63.0-3.0-2.92.81.7-0.93.8-2.2-2.03.5-3.03.02.6
Time in familiar zone, hab. session 10.40.41.00.8-0.8-0.70.60.9-0.70.5-1.0-0.70.20.0-0.0-0.2
Time in novel zone, hab. session 10.20.20.3-0.50.50.5-0.6-0.30.5-0.50.40.5-0.10.1-0.1-0.0
Total zone transitions, hab. session 10.10.10.2-0.20.20.2-0.30.0-0.0-0.50.10.1-0.50.5-0.5-0.4
Total locomotion distance, hab. session 11.52.13.4-1.81.81.7-1.8-1.30.9-1.81.41.4-1.51.1-1.1-0.9
Locomotion velocity, hab. session 12.73.96.3-2.52.52.4-2.5-2.11.6-2.32.12.0-1.71.1-1.1-0.7
Time in familiar zone, hab. session 20.10.10.20.3-0.3-0.20.20.3-0.10.5-0.4-0.20.3-0.30.30.2
Time in novel zone, hab. session 20.20.20.3-0.60.60.6-0.6-0.40.4-0.60.50.5-0.30.2-0.2-0.1
Total zone transitions, hab. session 20.20.20.4-0.60.60.6-0.7-0.50.4-0.40.50.5-0.30.2-0.2-0.1
Total locomotion distance, hab. session 20.81.11.8-1.31.31.3-1.3-1.20.8-1.01.11.1-0.80.5-0.5-0.3
Locomotion velocity, hab. session 20.91.22.0-1.41.41.4-1.4-1.20.8-1.21.21.1-1.00.7-0.7-0.5
Novel to familiar place preference ratio2.32.54.71.3-1.4-1.31.32.0-2.2-0.4-1.3-1.5-1.31.9-1.9-2.1
Novelty place preference2.52.65.11.4-1.5-1.51.42.1-2.2-0.3-1.4-1.6-1.21.8-1.8-2.0
Time in novel zone, NPP test2.32.54.91.5-1.5-1.41.32.1-2.2-0.2-1.5-1.5-1.11.7-1.7-1.9
Total zone transitions, NPP test0.81.22.1-1.31.31.3-1.4-1.41.4-0.51.21.30.0-0.40.40.6
Total locomotion distance, NPP test2.93.96.7-2.62.62.5-2.6-2.31.8-2.02.22.2-1.30.7-0.7-0.3
Locomotion velocity, NPP test2.63.76.4-2.52.52.3-2.3-2.41.9-1.82.42.1-1.10.5-0.5-0.1
Intraocular pressure0.30.50.90.4-0.5-0.20.10.9-0.8-0.2-0.9-0.4-0.90.9-0.9-1.0
Delta distance traveled before/after self-admin1.51.52.61.6-1.6-1.61.61.4-0.91.4-1.3-1.40.9-0.50.50.4
Delta ambulatory time before/after self-admin1.82.23.61.9-1.9-1.91.81.5-0.91.7-1.5-1.61.3-1.00.90.7
Parametrial fat weight0.92.03.8-1.61.61.6-1.6-1.91.9-0.21.51.70.4-1.01.01.3
Pavlov. Cond. lever latency0.20.30.70.6-0.6-0.50.60.6-0.80.5-0.7-0.60.00.1-0.1-0.3
Pavlov. Cond. magazine entry latency1.72.14.4-1.71.71.6-1.6-1.92.1-0.91.81.70.3-0.70.71.0
Pavlov. Cond. change in total contacts0.80.82.0-1.01.00.9-1.0-1.21.4-0.31.11.00.4-0.70.70.9
Pavlov. Cond. index score1.21.52.6-1.51.51.4-1.5-1.51.6-1.11.51.4-0.2-0.10.10.4
Pavlov. Cond. latency score1.01.22.4-1.31.41.2-1.3-1.41.6-0.91.41.3-0.0-0.30.30.6
Pavlov. Cond. lever contacts0.60.71.4-1.11.11.0-1.0-1.01.2-0.71.01.0-0.1-0.10.10.3
Pavlov. Cond. magazine entry number0.50.71.60.8-0.9-0.70.71.1-1.30.3-1.0-0.9-0.50.6-0.6-0.9
Pavlov. Cond. intertrial magazine entries0.20.20.4-0.50.50.5-0.4-0.10.1-0.50.30.3-0.60.6-0.6-0.5
Pavlov. Cond. lever-magazine prob. diff.1.11.42.3-1.41.51.4-1.4-1.41.5-1.01.41.3-0.2-0.10.10.4
Pavlov. Cond. response bias0.60.71.7-1.01.00.8-0.8-1.11.3-0.51.10.90.2-0.40.40.7
Pavlov. Cond. lever latency1.72.34.32.0-2.0-1.81.82.1-1.90.8-1.8-1.70.20.3-0.3-0.6
Pavlov. Cond. magazine entry latency1.31.62.9-1.61.71.5-1.5-1.71.6-0.71.41.4-0.2-0.30.30.6
Pavlov. Cond. change in total contacts0.71.02.1-1.21.21.1-1.1-1.51.4-0.11.21.10.2-0.60.60.8
Pavlov. Cond. index score2.12.95.4-2.22.22.0-2.0-2.32.1-0.92.01.9-0.3-0.40.40.8
Pavlov. Cond. latency score2.02.64.9-2.12.12.0-1.9-2.22.0-0.92.01.8-0.4-0.30.30.6
Pavlov. Cond. lever contacts1.62.24.1-1.91.91.8-1.7-2.01.8-0.71.81.7-0.1-0.40.40.7
Pavlov. Cond. magazine entry number3.74.68.22.8-2.8-2.62.62.9-2.61.4-2.5-2.40.50.3-0.3-0.8
Pavlov. Cond. intertrial magazine entries1.42.13.71.9-1.9-1.81.71.9-1.80.9-1.6-1.60.20.3-0.3-0.7
Pavlov. Cond. lever-magazine prob. diff.2.22.95.4-2.22.22.1-2.1-2.32.1-0.92.01.9-0.3-0.40.40.7
Pavlov. Cond. response bias2.12.85.2-2.12.12.0-2.0-2.32.2-0.82.01.9-0.1-0.60.60.9
Time in closed arm before self-admin0.40.51.40.4-0.4-0.30.40.5-1.2-0.2-0.1-0.6-0.71.0-1.0-1.1
Time in closed arm after self-admin0.10.10.20.2-0.2-0.20.20.2-0.50.00.2-0.3-0.30.4-0.3-0.5
Time in open arm before self-admin0.30.40.90.7-0.7-0.70.60.9-0.70.2-0.7-0.6-0.20.5-0.5-0.6
Time in open arm after self-admin0.10.20.40.4-0.4-0.30.30.6-0.5-0.2-0.5-0.3-0.10.4-0.4-0.4
Bone: periosteal estimation1.42.95.42.0-2.0-2.01.91.3-0.82.3-1.5-1.41.9-1.61.61.3
Bone: periosteal perimeter1.72.95.52.0-1.9-2.01.91.2-0.82.3-1.5-1.42.0-1.61.61.3
Bone: post-yield work0.30.50.90.9-0.9-0.90.80.8-0.50.8-0.7-0.70.6-0.40.40.2
Progressive ratio test 1 active lever presses0.10.10.2-0.20.20.2-0.2-0.0-0.1-0.1-0.1-0.1-0.20.5-0.5-0.5
Progressive ratio test 1 breakpoint0.10.10.2-0.40.40.3-0.3-0.2-0.0-0.20.00.0-0.20.5-0.4-0.4
Progressive ratio test 1 inactive lever presses0.10.10.30.3-0.3-0.30.40.3-0.50.6-0.3-0.50.10.2-0.2-0.3
Progressive ratio test 2 active lever presses0.20.20.7-0.00.00.1-0.10.2-0.5-0.4-0.2-0.2-0.60.8-0.8-0.8
Progressive ratio test 2 breakpoint0.20.20.6-0.10.10.1-0.10.2-0.4-0.5-0.2-0.1-0.60.7-0.7-0.8
Progressive ratio test 2 inactive lever presses0.30.51.50.3-0.3-0.20.20.6-1.0-0.2-0.7-0.6-0.61.1-1.1-1.2
Incentive Sensitization - Responses0.10.10.3-0.10.10.1-0.10.1-0.3-0.40.00.1-0.60.5-0.5-0.5
Incentive Sensitization - Breakpoint0.10.10.4-0.30.20.3-0.3-0.1-0.1-0.50.20.3-0.60.4-0.4-0.4
Sum of active levers in priming session hrs 5-60.10.10.2-0.20.20.2-0.10.20.1-0.00.20.1-0.40.5-0.5-0.3
Progressive ratio0.30.50.80.6-0.6-0.60.70.30.00.9-0.5-0.40.9-0.90.90.8
Food seeking constrained by brief footshock0.81.02.1-1.41.41.2-1.2-1.41.3-0.21.31.0-0.2-0.20.20.4
Seeking ratio, punishment vs. effort1.21.72.9-1.71.71.6-1.6-1.41.1-1.21.51.4-0.90.6-0.6-0.4
Retroperitoneal fat weight0.10.20.7-0.10.10.1-0.1-0.30.60.5-0.10.20.6-0.80.80.8
Reaction time number correct1.42.74.72.1-2.2-2.02.02.1-1.91.4-1.9-1.90.60.0-0.0-0.4
Reaction time mean minus median0.51.23.4-0.40.40.3-0.3-0.91.50.70.20.71.3-1.71.71.8
Reaction time mean minus median AUC0.30.72.1-0.00.1-0.0-0.1-0.41.00.7-0.10.31.1-1.41.41.5
Reaction time num false alarms0.20.31.1-0.00.00.1-0.2-0.20.80.50.10.20.7-0.90.91.0
Reaction time num false alarms AUC0.40.61.9-0.10.10.1-0.2-0.41.00.60.20.31.0-1.31.31.4
Reaction time trials correct on left1.42.74.72.1-2.2-2.02.02.1-1.91.4-1.9-1.90.60.0-0.0-0.4
Reaction time trials on left1.42.64.52.1-2.1-1.92.02.0-1.81.4-1.8-1.80.6-0.00.0-0.3
Reaction time mean0.91.53.2-1.31.31.3-1.3-1.61.8-0.41.11.40.4-1.01.01.2
Reaction time mean AUC0.91.53.1-1.31.41.3-1.4-1.61.8-0.51.21.40.2-0.80.81.1
Median of all reaction times0.60.91.6-1.11.11.1-1.2-1.21.3-0.61.01.2-0.1-0.40.40.6
Reaction time omissions0.50.71.90.1-0.0-0.00.1-0.60.70.70.50.41.2-1.31.31.4
Reaction time false alarm rate0.91.23.0-1.01.11.0-1.1-1.31.7-0.11.01.10.6-1.11.11.3
Reaction time premature initiation rate2.12.96.3-1.81.81.5-1.4-2.32.5-0.11.51.61.0-1.71.72.0
Reaction time premature initiations0.81.43.3-0.70.80.5-0.5-1.31.60.60.60.71.3-1.71.71.8
Std. dev. reaction times1.22.35.6-0.80.90.7-0.7-1.52.10.70.81.21.6-2.22.22.4
Reaction time trials completed1.42.64.52.1-2.1-1.92.02.0-1.81.4-1.8-1.80.6-0.00.0-0.3
Reaction time trials AUC1.42.64.52.1-2.1-1.91.92.1-1.91.3-1.8-1.90.50.1-0.1-0.4
Run reversals in cocaine runway, females0.80.82.30.0-0.00.1-0.10.3-1.1-1.1-0.0-0.1-1.31.4-1.4-1.5
Run reversals in cocaine runway, males3.33.35.8-2.42.42.3-2.3-2.22.0-1.62.02.1-1.00.2-0.20.2
Latency to leave start box in cocaine runway3.13.65.62.4-2.4-2.32.32.0-1.52.2-2.2-2.11.5-1.01.00.6
Latency to leave start box in cocaine runway, F4.14.77.62.7-2.7-2.72.72.4-1.92.5-2.5-2.41.4-0.80.80.4
Latency to leave start box in cocaine runway, M0.50.50.70.8-0.8-0.70.80.7-0.50.7-0.8-0.70.9-0.50.50.4
Std. dev. time between licks in bursts0.30.30.7-0.60.60.7-0.7-0.30.1-0.60.40.4-0.80.7-0.7-0.6
Total sessions with >9 infusions0.10.10.30.2-0.2-0.20.20.3-0.60.2-0.3-0.4-0.10.4-0.4-0.5
Short access day 1 total inactive lever presses1.82.45.71.7-1.7-1.71.71.8-2.41.0-1.5-1.90.00.9-0.9-1.3
Short access day 10 total inactive lever presses0.10.20.4-0.50.60.4-0.4-0.60.70.00.70.40.3-0.30.30.4
Short access day 1 total infusions0.60.82.2-0.60.60.6-0.5-0.2-0.7-0.80.40.1-1.21.5-1.5-1.5
Short access day 10 total infusions0.20.30.6-0.80.70.7-0.7-0.60.3-0.40.50.4-0.30.4-0.4-0.3
Short access total infusions0.10.10.4-0.10.10.0-0.00.1-0.50.0-0.2-0.3-0.20.6-0.6-0.6
Short access day 1 locomotion1.62.04.11.5-1.5-1.51.41.9-2.00.6-1.5-1.7-0.41.1-1.1-1.4
Short access day 10 total locomotion0.10.20.4-0.40.40.4-0.4-0.3-0.1-0.40.40.2-0.50.6-0.6-0.6
Short access total locomotion0.30.30.70.4-0.5-0.40.40.7-0.80.3-0.6-0.7-0.20.7-0.7-0.8
One hour access (0.3 mA shock)0.30.30.50.7-0.7-0.70.70.6-0.70.6-0.7-0.70.2-0.10.1-0.1
Compulsive drug intake0.91.12.01.1-1.1-1.11.20.5-0.31.4-0.5-0.61.3-1.31.31.2
One hour access (shock baseline)0.00.00.1-0.10.1-0.0-0.1-0.00.10.0-0.3-0.10.1-0.00.0-0.0
Social response proportion2.42.75.22.0-2.1-1.91.82.2-2.30.9-1.8-1.9-0.10.6-0.6-1.0
Social responses0.70.91.51.2-1.2-1.11.01.1-0.81.1-1.1-1.00.8-0.60.60.4
Social time0.10.10.2-0.00.10.1-0.0-0.20.30.10.40.20.5-0.40.40.5
Soleus weight0.72.13.82.0-1.9-1.91.81.7-1.51.5-1.6-1.60.9-0.40.40.1
Bone: stiffness0.20.30.90.3-0.3-0.30.20.10.40.8-0.2-0.01.0-0.90.90.9
Tibialis anterior weight0.41.32.41.6-1.6-1.41.41.4-1.00.8-1.2-1.20.8-0.30.30.2
Time to tail flick, vehicle, before self-admin0.90.92.70.1-0.2-0.10.00.8-1.0-0.6-0.4-0.4-1.31.6-1.6-1.7
Time to tail flick, vehicle, after self-admin0.30.40.70.8-0.8-0.80.70.9-0.60.7-0.6-0.70.30.1-0.1-0.1
Time to tail flick, test, before self-admin0.20.20.40.4-0.4-0.50.40.7-0.30.5-0.4-0.5-0.10.2-0.3-0.2
Time to tail flick, test, after self-admin0.70.71.60.4-0.5-0.40.40.9-1.1-0.1-0.7-0.7-0.91.2-1.2-1.3
Delta time to tail flick, vehicle, before/after SA0.10.10.30.3-0.2-0.20.20.00.10.30.1-0.10.6-0.40.40.4
Delta time to tail flick, test, before/after SA0.30.30.7-0.20.10.3-0.20.1-0.5-0.6-0.0-0.0-0.80.8-0.8-0.9
Tibia length0.20.40.9-0.50.50.3-0.4-0.80.90.30.40.50.6-0.90.90.9
Ambulatory time before self-admin0.20.30.80.4-0.4-0.30.40.7-0.9-0.1-0.4-0.4-0.40.7-0.7-0.8
Ambulatory time after self-admin1.51.83.31.7-1.7-1.61.61.8-1.70.8-1.5-1.60.10.5-0.5-0.8
Bone: tissue strength0.20.20.50.4-0.4-0.40.40.1-0.10.7-0.2-0.20.6-0.50.50.5
Total heroin consumption0.30.40.7-0.70.70.8-0.7-0.40.8-0.70.70.7-0.20.2-0.20.1
Bone: trabecular number0.61.11.91.3-1.3-1.31.41.2-1.30.9-1.0-1.20.30.1-0.1-0.4
Bone: trabecular spacing0.91.22.7-1.11.11.2-1.2-1.31.6-0.10.91.20.6-1.01.01.2
Bone: trabecular thickness0.80.91.61.1-1.1-1.11.10.6-0.51.3-0.7-0.71.2-1.01.00.8
Bone: trabecular tissue density0.91.32.31.5-1.5-1.41.31.4-1.11.0-1.5-1.30.5-0.30.30.0
Water consumed over 24 hours0.30.41.0-0.50.50.4-0.4-0.1-0.2-0.70.30.2-1.01.0-1.0-0.9
Number of responses in last shaping day0.10.10.20.3-0.3-0.40.30.4-0.30.4-0.4-0.40.20.1-0.1-0.1