Hub : Genes

Kxd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Kxd1 0.07 0.04 2.7e-05 0.01 0.01 0 0.01 6.7e-02 8.6e-03 2.4e-01 8.3e-03
2 BLA gene expression Kxd1 0.08 0.05 6.0e-04 0.05 0.04 0.04 0.04 1.0e-03 2.4e-03 3.9e-03 5.7e-03
3 Brain gene expression Kxd1 0.02 0.01 3.7e-03 0.03 0.03 0.03 0.03 4.9e-04 1.5e-03 7.8e-04 8.8e-04
4 NAcc gene expression Kxd1 0.03 0.02 9.4e-04 0.02 0.01 0.01 0.02 7.9e-04 1.7e-02 2.1e-03 1.6e-03
5 OFC intron excision ratio chr16_18936684_18943929 0.33 0.16 1.7e-03 0.11 0.06 0.1 0.11 1.5e-03 1.8e-02 2.6e-03 1.7e-03
6 PL gene expression Kxd1 0.03 0.02 5.2e-04 0.04 0.03 0.03 0.03 1.0e-04 5.6e-04 8.1e-04 6.4e-04
7 IC isoform ratio XM_006252922.5 0.06 0.04 6.4e-03 0 0.05 0.01 0.01 2.0e-01 4.5e-03 1.4e-01 1.6e-01
8 RMTg alternative polyA XM_039094765.1 0.15 0.09 5.5e-03 0.01 0.04 0.02 0.05 1.2e-01 2.5e-02 9.7e-02 1.8e-02
9 NAcc isoform ratio XM_006252922.5 0.03 0.02 6.9e-03 -0 0 0 -0 4.4e-01 1.3e-01 2.1e-01 7.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density2.13.612.4-1.9-2.5-0.7-0.72.6-1.20.6-3.5-0.4
Area under the delay curve0.10.10.50.70.30.30.4-0.2-0.0-0.00.2-0.0
BMI with tail1.34.38.3-2.9-2.5-2.4-2.22.3-1.9-1.7-1.2-0.7
BMI without tail2.47.410.3-3.0-3.1-3.1-2.73.2-2.8-2.7-1.3-1.6
Body weight4.720.533.8-5.8-5.5-5.0-4.55.3-4.2-3.1-3.8-2.4
Weight adjusted by age1.62.43.8-1.4-1.7-1.7-1.51.9-1.6-1.5-1.0-1.1
Bone surface1.12.06.4-1.4-2.0-0.5-0.61.9-0.40.7-2.50.4
Bone volume2.03.59.9-2.0-2.7-1.1-1.12.7-1.10.1-3.1-0.3
Breakpoint value in progressive ratio session0.10.10.7-0.3-0.3-0.10.8-0.30.3-0.00.30.4
Number of licking bursts0.10.20.50.20.70.40.2-0.70.30.40.50.2
Context. condit. distance diff. score0.30.31.2-0.61.10.2-0.5-0.7-0.30.10.4-0.5
Locomotion velocity, session 11.11.13.3-0.40.90.70.5-1.01.20.51.61.8
Locomotion distance, session 11.92.45.40.31.31.71.5-1.11.92.00.72.3
Locomotion velocity, session 20.60.81.8-1.3-0.3-1.1-0.50.2-1.0-1.30.9-0.3
Locomotion distance, session 22.13.05.90.71.31.92.1-1.42.02.10.62.4
Locomotion velocity, session 31.31.54.50.22.00.80.7-2.10.40.11.80.3
Locomotion distance, session 30.50.51.7-0.10.30.90.5-0.10.81.3-0.60.9
Stereotopy head waving bouts, day 31.21.45.6-0.32.00.80.5-2.40.30.80.9-0.1
Stereotopy head waving duration, day 30.70.83.2-0.51.60.30.1-1.8-0.10.11.0-0.4
Locomotion velocity, session 71.21.31.71.21.21.21.1-1.31.30.81.11.0
Locomotion distance, session 71.11.42.81.70.81.31.2-0.71.51.20.31.1
Stereotopy head waving bouts, day 70.30.32.4-1.50.2-0.2-0.2-0.4-0.40.2-0.2-0.2
Stereotopy head waving duration, day 70.60.83.0-1.70.3-0.7-0.7-0.6-1.0-0.70.3-0.8
Locomotion velocity, session 82.83.48.80.13.01.61.2-2.51.20.82.71.4
Locomotion distance, session 80.81.22.4-0.21.21.30.8-0.91.11.50.61.6
Degree of sensitization distance0.50.51.81.40.70.40.6-0.60.5-0.10.80.1
Degree of sensitization stereotypy0.50.63.1-1.8-0.6-0.6-0.70.5-0.50.1-0.7-0.2
Conditioned locomotion0.10.10.20.0-0.2-0.0-0.4-0.30.10.4-0.4-0.2
Cocaine response after cond. corrected0.50.73.10.60.1-0.3-0.7-0.7-1.0-0.6-0.2-1.8
Cocaine response after cond. not corrected0.50.61.61.00.90.20.1-1.2-0.4-0.30.7-1.0
Cocaine response before conditioning1.61.93.80.81.41.11.7-0.81.50.61.72.0
Saline control response0.20.30.9-0.40.30.60.5-0.10.40.60.10.9
Bone: connectivity density1.62.67.7-1.2-2.3-0.5-0.62.6-0.60.6-2.80.1
Bone: cortical apparent density0.30.41.61.0-0.40.61.30.30.10.10.30.7
Bone: cortical area6.810.416.5-4.1-4.0-3.2-3.03.6-2.8-1.9-3.5-2.1
Bone: cortical porosity0.30.41.6-0.2-0.10.30.30.21.00.60.21.3
Bone: cortical porosity0.30.41.6-0.3-0.10.30.20.20.90.7-0.01.2
Bone: cortical thickness4.98.116.9-4.1-3.4-2.6-2.63.0-2.4-1.0-3.4-1.7
Bone: cortical thickness3.33.99.0-3.0-1.9-1.2-2.11.6-1.70.2-2.9-1.6
Bone: cortical tissue density0.40.51.81.2-0.20.71.30.10.20.10.40.7
Condit. Reinf. active minus inactive responses0.80.93.3-1.8-0.7-0.6-0.70.8-0.40.6-1.6-0.1
Condit. Reinf. active-inactive response ratio1.21.35.3-1.3-1.2-0.5-0.71.2-0.40.6-2.3-0.6
Condit. Reinf. active responses0.70.93.8-2.0-0.7-0.8-0.90.8-0.60.3-1.2-0.1
Condit. Reinf. inactive responses0.20.30.5-0.6-0.3-0.7-0.60.6-0.4-0.60.40.1
Incentive salience index mean0.81.04.9-2.2-0.9-0.8-0.60.7-0.40.4-1.10.4
Condit. Reinf. lever presses0.70.95.7-2.4-0.8-0.7-0.40.4-0.30.3-0.50.9
Condit. Reinf. active minus inactive responses0.20.20.5-0.10.40.60.6-0.20.70.6-0.10.7
Condit. Reinf. active-inactive response ratio0.30.31.0-1.0-0.5-0.6-0.40.5-0.5-0.4-0.5-0.4
Condit. Reinf. active responses1.21.62.21.01.51.41.4-1.11.40.81.11.5
Condit. Reinf. inactive responses3.03.96.12.42.42.01.8-2.01.80.72.51.6
Condit. Reinf. lever presses0.20.31.10.30.4-0.1-0.0-0.4-0.1-0.91.1-0.0
Condit. Reinf. lever reinforcers received0.40.50.80.70.90.70.8-0.70.80.10.90.7
Conditioned reinforcement - actives1.22.03.4-1.0-1.5-1.4-1.81.8-1.4-1.4-1.1-1.3
Conditioned reinforcement - inactives6.910.214.0-3.2-3.1-3.7-3.53.3-3.2-2.8-2.4-3.2
Conditioned locomotion1.41.83.5-0.6-1.1-1.3-1.91.3-1.5-1.6-0.5-1.6
Patch foraging indifference point 0 sec1.63.04.9-1.9-1.1-2.1-2.20.8-2.2-2.2-0.4-1.6
Patch foraging indifference point AUC0.20.41.21.00.20.20.6-0.3-0.2-0.61.1-0.0
Delay disc. indifference point, 0s delay2.93.25.01.82.22.01.8-2.01.51.22.01.3
Delay disc. indifference point, 16s delay0.91.04.32.11.00.91.0-0.80.60.10.90.2
Delay disc. indifference point, 2s delay0.60.71.10.30.81.01.0-1.00.61.00.20.9
Delay disc. indifference point, 24s delay0.20.30.80.40.3-0.3-0.4-0.0-0.5-0.90.9-0.4
Delay disc. indifference point, 4s delay0.10.10.3-0.10.30.30.4-0.30.00.20.10.5
Delay disc. indifference point, 8s delay0.20.30.80.5-0.2-0.3-0.00.2-0.7-0.80.2-0.9
Indifference point function ln k0.71.22.5-1.3-1.3-1.1-1.61.3-0.4-0.1-1.4-0.4
Indifference point function log k0.71.22.5-1.3-1.3-1.1-1.61.3-0.4-0.1-1.4-0.4
Patch foraging total patch changes 0 sec2.54.77.3-2.3-1.6-2.7-2.71.2-2.7-2.6-0.6-2.1
Patch foraging total patch changes 12 sec0.70.92.5-0.40.2-0.9-0.7-0.3-1.4-1.60.8-1.1
Patch foraging total patch changes 18 sec0.30.41.70.60.60.00.1-1.3-0.1-0.61.0-0.4
Patch foraging total patch changes 24 sec0.30.40.9-0.8-0.1-0.7-1.0-0.1-0.8-0.6-0.4-0.8
Patch foraging total patch changes 6 sec1.11.64.3-1.1-0.0-1.2-1.2-0.2-1.9-2.11.0-1.3
Patch foraging time to switch 0 sec1.12.24.51.31.51.52.1-1.21.51.11.31.5
Patch foraging water rate 0 sec0.81.62.5-1.6-1.4-1.4-1.61.2-1.4-1.0-0.8-0.8
Patch foraging water rate 12 sec0.61.33.1-1.1-1.5-0.8-1.21.8-0.4-0.0-1.7-0.1
Patch foraging water rate 18 sec0.40.61.8-0.1-0.80.40.00.90.81.1-0.81.3
Patch foraging water rate 24 sec1.01.43.3-1.4-1.6-0.4-0.61.80.00.8-1.80.9
Patch foraging water rate 6 sec1.42.04.3-1.3-1.6-1.6-2.11.5-1.2-0.9-1.3-0.9
Seeking ratio, delayed vs. immediate footshock1.31.64.60.81.50.81.4-0.91.00.62.11.5
Distance traveled before self-admin0.40.61.4-0.8-0.3-0.9-0.60.4-1.0-1.20.7-0.5
Distance traveled after self-admin0.81.02.3-1.5-0.8-1.3-0.91.1-0.9-1.00.1-0.4
Extensor digitorum longus weight0.20.82.3-1.5-0.2-0.9-0.9-0.5-1.2-1.10.6-0.6
Bone: elastic displacement0.40.51.3-0.20.30.70.90.20.71.0-0.11.1
Bone: elastic work1.62.13.7-1.9-1.6-1.5-1.21.7-1.5-1.0-1.4-0.9
Bone: endosteal estimation0.10.30.60.6-0.6-0.6-0.60.4-0.3-0.8-0.1-0.4
Bone: endosteal perimeter0.92.03.6-1.2-1.5-1.8-1.91.2-1.0-1.3-1.3-1.3
Epididymis fat weight0.92.99.1-1.2-2.8-1.5-0.83.0-1.1-1.1-1.50.1
Delta time in closed arm before/after self-admin0.20.20.50.7-0.2-0.2-0.3-0.5-0.5-0.60.2-0.6
Delta time in open arm before/after self-admin0.80.82.41.00.40.91.5-0.21.00.70.21.0
Diff in mean of infusions in LGA sessions0.91.03.8-0.3-0.2-1.3-0.30.4-1.2-1.91.3-0.7
Delay discount exponential model param0.00.00.1-0.3-0.1-0.0-0.00.00.30.20.10.3
Extinction: sum of active levers before priming0.80.92.50.3-0.10.91.40.11.01.1-0.21.6
Active lever presses in extinction session 60.40.40.70.80.60.70.8-0.60.40.10.70.5
Bone: final force7.011.115.7-3.6-4.0-3.7-3.63.2-3.3-2.7-2.9-2.7
Bone: final moment6.710.715.1-3.4-3.9-3.6-3.63.1-3.2-2.7-2.9-2.8
Food consumed during 24 hour testing period0.50.71.8-0.20.00.90.8-0.21.01.3-0.31.3
Glucose1.01.62.7-1.6-1.3-1.5-1.31.0-1.3-1.6-0.3-0.9
Heart weight1.62.59.3-3.1-1.0-1.3-2.01.0-1.2-0.2-1.7-1.1
Delay discount hyperbolic model param0.00.00.1-0.1-0.2-0.1-0.10.20.30.10.10.2
Intermittent access intake day 1-15 change0.51.03.3-1.1-1.2-0.6-0.61.6-0.20.3-1.8-0.2
Intermittent access intake escalation0.40.93.3-0.9-1.0-0.3-0.21.60.10.6-1.80.1
Intermittent access intake escalation 20.80.93.5-0.7-1.4-0.7-0.41.9-0.5-0.3-1.2-0.1
Intermitt. access day 1 inactive lever presses0.10.30.8-0.9-0.3-0.4-0.70.5-0.6-0.6-0.2-0.7
Intermitt. access day 15 inactive lever presses0.10.10.5-0.60.3-0.3-0.7-0.30.30.10.1-0.2
Intermitt. access escalation Index0.40.50.91.00.90.50.7-0.70.80.90.40.6
Intermittent access day 1 total infusions0.81.33.0-0.1-0.3-1.4-1.50.1-1.2-1.70.7-1.6
Intermittent access day 15 total infusions0.60.92.2-0.6-1.1-1.1-0.81.5-0.5-0.2-1.3-0.7
Intermittent access terminal intake (last 3 days)0.50.71.5-0.3-1.1-1.0-0.81.2-0.4-0.4-1.0-0.7
Intermittent access total infusions1.41.72.8-0.5-1.4-1.7-1.31.2-1.3-1.5-0.7-1.6
Intermittent access day 1 locomotion1.72.24.2-0.5-1.3-1.6-2.01.1-1.7-2.0-0.0-1.7
Intermittent access day 15 total locomotion0.30.51.2-0.3-1.1-0.3-0.80.9-0.3-0.3-0.9-0.5
Intermittent access total locomotion1.92.33.2-0.7-1.7-1.5-1.71.4-1.7-1.8-0.7-1.7
Intermittent access standard deviation0.10.31.0-0.4-0.6-0.5-0.61.0-0.4-0.6-0.2-0.4
Left kidney weight0.31.32.8-1.7-1.1-1.4-1.00.6-1.4-1.50.3-0.5
Right kidney weight0.93.96.9-2.4-2.6-2.4-1.52.1-2.1-2.4-0.3-0.7
Cocaine induced anxiety1.11.64.0-1.0-0.1-1.4-1.4-0.2-1.5-2.01.1-1.4
Post-drug Anxiety0.30.31.3-0.20.60.0-0.0-0.7-0.1-0.61.1-0.1
Baseline Anxiety2.52.95.11.31.12.12.3-0.92.02.20.12.0
Tail length0.83.05.8-2.0-2.0-1.9-1.32.4-1.9-1.6-1.0-0.9
Length with tail1.98.313.3-3.5-3.6-3.2-2.43.4-2.9-2.0-2.5-1.7
Length without tail2.06.410.6-3.3-3.2-2.5-2.32.6-2.1-0.9-3.1-1.7
Times rat made contact with spout0.30.30.70.4-0.20.50.7-0.20.80.80.00.8
Lifetime Intake2.42.94.8-1.1-1.6-2.2-2.11.5-1.7-1.8-0.9-2.0
Liver weight, left0.50.82.20.2-0.30.91.5-0.11.01.1-0.01.5
Liver weight, right1.22.15.9-1.1-2.4-1.5-0.62.3-1.2-1.4-0.9-0.3
Locomotor activity0.61.02.3-1.3-1.20.10.90.60.41.2-1.01.5
Locomotor testing distance0.50.92.3-0.5-0.40.71.10.10.81.5-0.91.5
Locomotor testing rearing0.50.93.40.10.10.91.30.40.91.3-0.11.8
Locomotion in novel chamber0.30.31.1-0.4-1.00.00.11.0-0.20.2-0.70.4
Locomotion in novel chamber post-restriction1.42.28.0-1.3-1.70.4-0.11.90.51.6-2.81.0
Fecal boli incidents, locomotor time 10.20.30.91.0-0.20.60.80.30.30.3-0.20.4
Change in fecal boli incidents, locomotor task1.01.03.00.81.40.50.4-1.60.5-0.11.70.2
Time >=10cm from walls, locomotor time 10.20.20.80.9-0.2-0.00.0-0.2-0.2-0.60.8-0.1
Bouts of movement, locomotor time 10.40.51.11.0-0.30.30.80.00.90.50.51.0
Total resting periods, locomotor time 10.80.92.01.40.10.61.0-0.21.30.90.61.3
Rest time, locomotor task time 10.20.20.60.70.7-0.00.1-0.80.1-0.10.70.0
Distance moved, locomotor task time 10.10.10.20.10.40.20.2-0.50.1-0.20.5-0.2
Vertical activity count, locomotor time 10.10.10.7-0.4-0.30.10.80.20.10.2-0.20.5
Time >=10cm from walls, locomotor time 20.50.71.60.81.01.20.6-0.90.71.00.20.4
Bouts of movement, locomotor time 20.10.20.6-0.30.70.20.3-0.80.30.30.50.3
Total resting periods, locomotor time 20.10.10.5-0.30.5-0.10.1-0.70.20.10.50.0
Rest time, locomotor task time 20.30.41.1-0.4-0.4-1.1-0.30.1-0.7-0.80.2-0.7
Distance moved, locomotor task time 20.10.10.40.50.40.70.1-0.30.30.3-0.1-0.1
Vertical activity count, locomotor time 20.10.20.6-0.60.10.40.2-0.0-0.10.5-0.7-0.2
Light reinforcement 10.10.20.50.70.0-0.10.1-0.2-0.3-0.70.6-0.2
Light reinforcement 20.81.23.01.20.3-0.5-0.2-0.8-1.1-1.71.1-1.5
Bone: marrow area0.10.20.40.7-0.6-0.5-0.50.3-0.2-0.6-0.1-0.3
Bone: maximum diameter2.85.37.9-2.8-2.3-2.5-2.72.1-2.1-1.6-2.3-2.0
Bone: maximum force6.211.017.4-4.0-4.2-3.5-3.43.5-3.0-2.2-3.3-2.1
Bone: maximum moment5.69.815.6-3.6-3.9-3.3-3.33.2-2.8-2.1-3.2-2.1
Mean time between licks in bursts1.12.84.1-2.0-1.9-2.0-1.62.0-1.6-1.7-0.9-1.1
Mean num. licks in bursts0.20.41.2-0.3-1.1-0.20.00.80.10.3-1.10.1
Cd content in liver3.53.99.9-1.5-2.4-1.5-1.92.5-1.4-0.2-3.2-1.7
Co content in liver0.00.00.1-0.20.1-0.00.0-0.1-0.0-0.0-0.2-0.3
Cu content in liver1.41.64.3-0.11.01.31.1-1.01.62.10.01.7
Fe content in liver0.80.92.01.40.70.91.4-1.10.80.60.90.5
K content in liver2.42.34.71.72.21.51.3-1.71.51.11.40.9
Mg content in liver0.10.10.60.20.80.3-0.1-0.40.40.30.30.0
Mn content in liver0.10.10.4-0.60.4-0.2-0.60.10.10.00.10.1
Na content in liver3.23.45.31.51.72.22.1-1.32.01.71.62.3
Rb content in liver2.02.46.2-1.2-0.7-1.5-2.10.7-1.6-1.1-1.5-2.5
Se content in liver0.30.30.6-0.10.70.70.5-0.40.70.80.10.6
Sr content in liver0.50.41.01.0-0.20.40.80.90.60.20.10.7
Zn content in liver0.10.10.20.10.20.00.40.10.30.00.30.4
Bone: minimum diameter2.03.78.0-1.8-2.8-2.1-1.72.4-1.6-1.6-1.8-1.0
Time in familiar zone, hab. session 10.20.21.30.0-0.7-0.40.01.1-0.2-0.5-0.10.1
Time in novel zone, hab. session 10.10.10.3-0.50.10.0-0.4-0.3-0.10.5-0.5-0.3
Total zone transitions, hab. session 10.60.82.60.70.31.01.10.21.11.00.41.6
Total locomotion distance, hab. session 11.52.26.10.80.51.51.80.21.82.00.02.5
Locomotion velocity, hab. session 11.62.26.21.00.71.51.8-0.11.91.70.52.5
Time in familiar zone, hab. session 20.10.10.20.0-0.1-0.2-0.40.3-0.2-0.40.2-0.1
Time in novel zone, hab. session 20.10.10.50.1-0.4-0.10.10.3-0.10.2-0.7-0.4
Total zone transitions, hab. session 20.10.20.40.10.20.40.1-0.40.60.60.10.5
Total locomotion distance, hab. session 20.50.72.3-0.6-0.00.70.40.10.91.5-0.71.2
Locomotion velocity, hab. session 20.60.82.4-0.30.20.80.6-0.11.11.6-0.41.4
Novel to familiar place preference ratio0.40.41.20.5-1.1-0.50.00.8-0.6-0.6-0.7-0.7
Novelty place preference0.30.30.60.6-0.8-0.40.10.6-0.4-0.4-0.5-0.6
Time in novel zone, NPP test0.20.20.70.8-0.7-0.10.30.4-0.1-0.1-0.4-0.3
Total zone transitions, NPP test0.81.22.60.50.61.30.9-0.61.41.60.21.6
Total locomotion distance, NPP test1.82.46.00.30.91.71.3-0.71.92.5-0.02.4
Locomotion velocity, NPP test1.62.35.20.51.11.71.4-0.81.92.20.22.3
Intraocular pressure1.42.03.9-1.5-0.9-1.7-1.30.6-1.7-1.3-1.1-2.0
Delta distance traveled before/after self-admin0.60.61.4-0.8-1.1-1.20.11.1-0.6-0.6-0.6-0.2
Delta ambulatory time before/after self-admin0.10.20.4-0.7-0.6-0.5-0.00.4-0.2-0.3-0.5-0.2
Parametrial fat weight2.66.111.6-0.9-2.4-3.1-2.62.5-2.8-3.4-0.5-2.5
Pavlov. Cond. lever latency0.40.52.11.40.1-0.1-0.6-0.3-0.1-0.70.3-1.1
Pavlov. Cond. magazine entry latency0.20.20.6-0.4-0.6-0.4-0.10.8-0.6-0.3-0.4-0.0
Pavlov. Cond. change in total contacts0.80.83.2-1.8-0.7-1.0-0.50.6-1.2-0.5-0.6-0.3
Pavlov. Cond. index score0.20.21.0-0.6-0.10.10.70.30.10.4-0.11.0
Pavlov. Cond. latency score0.30.41.4-0.80.30.30.8-0.10.20.60.21.2
Pavlov. Cond. lever contacts0.30.31.5-1.2-0.2-0.20.50.3-0.10.3-0.00.9
Pavlov. Cond. magazine entry number0.20.20.60.40.60.40.2-0.80.60.50.40.0
Pavlov. Cond. intertrial magazine entries0.60.82.3-1.5-0.00.3-0.30.20.31.5-1.40.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.6-0.6-0.00.10.50.2-0.00.20.10.8
Pavlov. Cond. response bias0.20.20.6-0.7-0.6-0.3-0.00.8-0.30.0-0.50.4
Pavlov. Cond. lever latency0.50.72.70.60.10.90.40.21.11.7-0.80.8
Pavlov. Cond. magazine entry latency0.40.51.6-0.5-0.3-0.6-0.30.2-1.0-1.30.4-0.9
Pavlov. Cond. change in total contacts0.50.82.3-0.90.2-0.8-0.6-0.3-1.2-1.50.8-0.9
Pavlov. Cond. index score0.81.13.5-0.9-0.1-1.1-0.7-0.0-1.4-1.90.8-1.2
Pavlov. Cond. latency score0.50.72.3-0.60.2-0.7-0.3-0.2-1.2-1.50.8-0.9
Pavlov. Cond. lever contacts0.50.72.3-0.60.1-0.7-0.3-0.5-1.1-1.51.0-0.8
Pavlov. Cond. magazine entry number1.11.43.81.00.81.30.8-0.61.62.0-0.41.3
Pavlov. Cond. intertrial magazine entries0.71.12.71.10.31.10.6-0.21.61.40.21.5
Pavlov. Cond. lever-magazine prob. diff.0.91.23.6-1.0-0.2-1.1-0.70.1-1.5-1.90.7-1.2
Pavlov. Cond. response bias0.70.93.2-0.8-0.3-1.0-0.70.0-1.2-1.80.8-0.9
Time in closed arm before self-admin4.25.49.8-2.9-0.5-3.1-2.41.3-2.7-3.10.8-2.3
Time in closed arm after self-admin4.24.48.4-1.4-0.8-2.7-2.41.1-2.7-2.90.2-2.7
Time in open arm before self-admin1.11.23.10.60.11.21.1-0.41.31.7-0.41.8
Time in open arm after self-admin2.52.76.90.20.41.91.6-0.12.02.6-0.82.6
Bone: periosteal estimation2.04.27.2-2.0-2.7-2.2-2.22.3-1.7-1.4-2.2-1.4
Bone: periosteal perimeter4.78.110.8-3.3-3.0-3.2-3.32.7-2.6-2.2-2.8-2.5
Bone: post-yield work0.20.31.0-0.1-0.60.1-0.10.10.40.8-1.00.4
Progressive ratio test 1 active lever presses2.22.75.3-1.5-1.1-2.0-2.30.8-1.9-2.0-0.0-1.7
Progressive ratio test 1 breakpoint2.02.45.0-1.5-1.0-2.0-2.20.8-1.8-1.9-0.0-1.6
Progressive ratio test 1 inactive lever presses1.11.52.2-1.5-0.9-1.5-1.41.2-1.3-1.4-0.3-1.1
Progressive ratio test 2 active lever presses0.91.11.7-0.4-0.9-1.3-1.10.9-1.1-1.3-0.4-1.3
Progressive ratio test 2 breakpoint0.70.81.3-0.3-0.8-1.1-0.90.8-1.0-1.1-0.4-1.1
Progressive ratio test 2 inactive lever presses1.11.83.2-1.8-1.0-1.8-1.80.9-1.1-1.0-0.9-1.4
Incentive Sensitization - Responses0.20.20.70.9-0.3-0.50.00.4-0.1-0.4-0.4-0.6
Incentive Sensitization - Breakpoint0.20.21.41.2-0.2-0.20.30.30.1-0.2-0.3-0.4
Sum of active levers in priming session hrs 5-63.12.97.81.00.42.01.8-0.42.12.8-1.31.8
Progressive ratio0.00.10.30.3-0.00.1-0.2-0.10.20.2-0.6-0.3
Food seeking constrained by brief footshock0.70.95.3-0.2-0.4-0.1-0.00.40.51.5-2.3-0.2
Seeking ratio, punishment vs. effort0.30.51.6-0.2-0.10.40.60.40.61.3-0.90.8
Retroperitoneal fat weight2.410.313.8-3.0-3.7-3.6-3.53.7-3.3-3.0-2.5-2.4
Reaction time number correct0.51.14.1-0.5-0.40.60.61.21.11.1-0.62.0
Reaction time mean minus median0.10.21.20.30.50.10.3-0.70.1-0.31.10.2
Reaction time mean minus median AUC0.10.31.3-0.10.6-0.2-0.4-0.60.0-0.41.1-0.2
Reaction time num false alarms0.81.12.3-1.1-0.3-1.2-1.2-0.1-1.3-1.2-0.8-1.5
Reaction time num false alarms AUC0.60.92.2-1.0-0.1-1.0-0.9-0.3-1.2-1.1-0.8-1.5
Reaction time trials correct on left0.51.14.1-0.5-0.40.60.61.21.11.1-0.62.0
Reaction time trials on left0.51.03.9-0.5-0.50.50.61.31.01.0-0.62.0
Reaction time mean0.81.33.60.2-0.6-1.2-1.00.2-1.3-1.90.4-1.7
Reaction time mean AUC0.50.82.60.80.1-0.7-0.6-0.4-0.8-1.61.1-1.3
Median of all reaction times1.11.64.30.2-0.6-1.3-1.20.3-1.5-2.00.1-2.1
Reaction time omissions0.91.33.4-0.8-0.9-1.5-1.00.6-1.2-1.80.5-1.0
Reaction time false alarm rate1.21.64.9-0.9-0.3-1.3-1.3-0.5-1.6-1.4-0.7-2.2
Reaction time premature initiation rate0.40.51.3-0.30.30.70.3-0.81.01.1-0.01.0
Reaction time premature initiations0.40.83.0-0.60.00.70.4-0.01.21.2-0.11.7
Std. dev. reaction times0.30.51.4-0.2-0.6-0.8-0.50.1-0.8-1.20.7-0.7
Reaction time trials completed0.51.03.9-0.5-0.50.50.61.31.01.0-0.62.0
Reaction time trials AUC0.50.93.2-0.6-0.60.30.41.50.90.8-0.81.8
Run reversals in cocaine runway, females3.73.77.0-2.0-1.8-2.7-2.51.8-1.7-1.7-1.0-1.7
Run reversals in cocaine runway, males1.31.42.51.01.01.11.1-1.61.41.00.91.2
Latency to leave start box in cocaine runway0.10.10.20.4-0.3-0.1-0.20.10.2-0.00.30.3
Latency to leave start box in cocaine runway, F0.20.30.8-0.5-0.9-0.8-0.60.5-0.3-0.1-0.40.1
Latency to leave start box in cocaine runway, M0.70.62.51.60.80.70.5-0.50.6-0.01.00.2
Std. dev. time between licks in bursts1.82.53.9-1.6-2.0-1.7-1.52.0-1.5-1.2-1.4-1.1
Total sessions with >9 infusions4.35.211.2-2.0-2.0-2.6-3.32.1-2.4-2.2-1.1-2.3
Short access day 1 total inactive lever presses1.62.14.5-1.2-1.2-1.6-2.11.5-1.3-1.1-1.1-1.7
Short access day 10 total inactive lever presses0.61.55.40.21.90.60.3-1.90.5-0.32.30.1
Short access day 1 total infusions3.85.07.6-2.2-2.4-2.5-2.72.8-2.1-1.6-1.9-1.8
Short access day 10 total infusions1.21.54.1-1.2-1.0-1.5-2.01.4-0.9-0.6-1.0-0.9
Short access total infusions2.43.06.7-1.4-1.4-2.2-2.61.6-1.6-1.6-0.9-1.7
Short access day 1 locomotion6.07.411.2-2.3-2.3-3.1-3.32.7-3.1-2.7-1.6-2.9
Short access day 10 total locomotion1.63.05.9-2.4-2.1-1.7-2.02.4-1.1-0.5-1.6-0.5
Short access total locomotion3.44.07.6-2.0-2.1-2.1-2.82.1-1.9-1.4-1.7-1.7
One hour access (0.3 mA shock)0.91.01.9-0.9-0.6-1.0-0.91.1-1.0-0.4-1.4-1.4
Compulsive drug intake0.70.81.21.11.10.80.9-1.11.01.00.30.4
One hour access (shock baseline)2.03.04.0-1.5-1.5-1.9-1.81.8-2.0-1.7-1.2-1.9
Social response proportion3.94.410.5-2.7-2.3-1.8-1.81.9-1.8-0.4-3.2-1.7
Social responses1.11.45.3-1.7-1.2-0.3-0.01.3-0.31.0-2.30.2
Social time0.20.31.7-1.30.2-0.2-0.1-0.5-0.30.3-0.5-0.5
Soleus weight0.82.44.7-0.6-1.3-1.9-1.81.1-1.9-2.2-0.2-1.7
Bone: stiffness4.47.211.8-3.4-3.0-3.0-3.02.3-2.6-2.1-2.2-2.1
Tibialis anterior weight0.10.41.3-1.1-1.1-0.30.10.6-0.20.3-0.40.8
Time to tail flick, vehicle, before self-admin0.30.41.20.3-0.8-0.4-0.80.30.1-0.1-1.1-0.6
Time to tail flick, vehicle, after self-admin0.20.20.80.20.0-0.3-0.2-0.1-0.5-0.90.8-0.1
Time to tail flick, test, before self-admin2.02.13.9-1.7-0.8-1.6-1.50.8-1.8-1.4-0.9-2.0
Time to tail flick, test, after self-admin0.30.31.31.10.30.90.1-0.30.50.5-0.3-0.4
Delta time to tail flick, vehicle, before/after SA0.50.41.50.00.90.60.5-0.60.10.11.20.8
Delta time to tail flick, test, before/after SA1.11.12.71.70.11.30.80.21.41.3-0.21.2
Tibia length0.51.43.3-1.8-1.1-1.3-1.40.8-1.1-0.7-0.9-0.8
Ambulatory time before self-admin0.60.92.7-0.9-0.3-1.0-0.20.7-1.3-1.61.2-0.5
Ambulatory time after self-admin1.31.63.3-1.8-1.3-1.6-0.61.5-1.3-1.40.1-0.5
Bone: tissue strength0.20.20.60.2-0.3-0.4-0.00.0-0.1-0.80.70.1
Total heroin consumption0.20.20.6-0.0-0.3-0.40.3-0.6-0.4-0.80.5-0.3
Bone: trabecular number2.03.49.3-1.8-2.6-0.8-0.82.9-1.20.2-3.0-0.2
Bone: trabecular spacing0.40.51.60.80.90.20.3-0.80.5-0.31.3-0.0
Bone: trabecular thickness1.41.85.7-1.5-2.0-0.5-0.61.7-0.80.5-2.4-0.0
Bone: trabecular tissue density0.60.92.30.80.30.91.2-0.21.30.80.71.5
Water consumed over 24 hours0.30.40.9-0.4-1.00.10.10.80.50.8-0.90.7
Number of responses in last shaping day0.91.03.1-1.2-1.1-0.6-1.01.3-0.20.5-1.7-0.2