Hub : Genes

Kti12

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Kti12 0.21 0.12 1.1e-11 0.07 0.13 0.12 0.12 5.5e-07 7.1e-12 1.9e-11 2.2e-11
2 IC gene expression Kti12 0.33 0.17 2.3e-07 0.1 0.15 0.17 0.14 3.9e-05 1.0e-06 1.2e-07 1.8e-06
3 BLA gene expression Kti12 0.22 0.14 2.3e-08 0.14 0.13 0.14 0.14 1.0e-07 1.8e-07 1.0e-07 1.1e-07
4 IL gene expression Kti12 0.2 0.14 8.3e-03 0.08 0.04 0.02 0.05 6.6e-03 3.6e-02 1.0e-01 2.1e-02
5 NAcc gene expression Kti12 0.09 0.06 9.7e-12 0.07 0.07 0.07 0.07 5.9e-11 2.0e-10 3.8e-11 5.2e-11
6 PL gene expression Kti12 0.16 0.1 2.4e-12 0.08 0.09 0.09 0.1 1.7e-09 3.4e-10 2.9e-10 9.2e-11
7 pVTA gene expression Kti12 0.04 0.04 1.9e-03 0.04 0.03 0.01 0.03 3.0e-04 2.0e-03 3.5e-02 1.2e-03
8 Liver gene expression Kti12 0.31 0.16 0.0e+00 0.17 0.17 0.17 0.17 9.2e-19 7.4e-19 2.6e-18 1.7e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bone: apparent density0.50.81.1-0.4-0.8-0.9-1.0-0.9-1.0-1.0-1.0
Area under the delay curve0.10.10.5-0.7-0.4-0.2-0.3-0.2-0.2-0.10.3
BMI with tail1.75.76.62.12.62.52.62.62.42.51.8
BMI without tail0.82.32.91.21.61.61.71.61.51.61.3
Body weight0.93.84.41.72.12.02.12.02.02.01.5
Weight adjusted by age0.40.61.41.21.00.80.60.70.70.60.2
Bone surface0.20.40.5-0.6-0.7-0.7-0.7-0.7-0.7-0.7-0.4
Bone volume0.00.00.0-0.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Breakpoint value in progressive ratio session0.00.00.00.1-0.0-0.0-0.2-0.1-0.1-0.1-0.2
Number of licking bursts0.30.40.70.90.90.70.50.70.60.50.0
Context. condit. distance diff. score0.30.30.80.1-0.3-0.6-0.5-0.5-0.6-0.6-0.9
Locomotion velocity, session 12.42.54.8-0.3-1.2-1.5-1.8-1.6-1.6-1.8-2.2
Locomotion distance, session 10.00.10.20.40.20.0-0.10.0-0.1-0.1-0.5
Locomotion velocity, session 22.12.44.8-0.2-1.2-1.5-1.8-1.5-1.6-1.8-2.2
Locomotion distance, session 20.40.51.5-0.30.40.60.90.70.70.81.2
Locomotion velocity, session 30.70.81.2-0.5-0.9-1.0-0.9-0.9-1.1-1.0-1.0
Locomotion distance, session 30.10.10.4-0.6-0.1-0.10.20.00.10.10.6
Stereotopy head waving bouts, day 30.10.10.20.40.30.20.00.20.00.1-0.5
Stereotopy head waving duration, day 30.30.31.60.90.20.0-0.3-0.0-0.3-0.3-1.3
Locomotion velocity, session 70.40.51.4-1.2-0.7-0.8-0.3-0.7-0.5-0.50.3
Locomotion distance, session 70.70.93.7-1.9-1.0-0.8-0.3-0.7-0.4-0.41.1
Stereotopy head waving bouts, day 71.31.42.9-0.3-0.9-1.1-1.2-1.1-1.4-1.3-1.7
Stereotopy head waving duration, day 71.31.53.3-0.2-0.9-1.1-1.2-1.1-1.4-1.3-1.8
Locomotion velocity, session 81.72.12.6-0.8-1.3-1.6-1.6-1.5-1.4-1.6-1.5
Locomotion distance, session 80.00.00.1-0.3-0.1-0.3-0.1-0.2-0.3-0.2-0.1
Degree of sensitization distance0.10.10.4-0.4-0.00.00.10.10.20.10.6
Degree of sensitization stereotypy0.80.81.3-0.3-0.8-0.9-0.8-0.9-1.2-0.9-1.1
Conditioned locomotion0.40.51.41.20.90.70.40.60.50.4-0.3
Cocaine response after cond. corrected1.41.73.90.00.91.21.51.31.31.52.0
Cocaine response after cond. not corrected2.12.43.90.51.31.51.81.61.61.82.0
Cocaine response before conditioning0.20.20.50.70.50.40.30.40.40.3-0.2
Saline control response0.40.52.4-1.5-0.7-0.5-0.1-0.4-0.2-0.11.0
Bone: connectivity density1.11.82.0-1.1-1.4-1.4-1.4-1.4-1.4-1.4-1.0
Bone: cortical apparent density1.52.13.5-0.4-1.2-1.4-1.6-1.5-1.5-1.6-1.9
Bone: cortical area1.01.62.30.51.11.31.31.31.41.41.5
Bone: cortical porosity0.50.52.21.50.70.4-0.00.30.20.0-1.1
Bone: cortical porosity0.40.41.81.10.30.0-0.4-0.1-0.2-0.4-1.4
Bone: cortical thickness2.64.45.11.42.22.22.22.22.32.21.9
Bone: cortical thickness2.42.83.51.61.91.81.61.81.81.71.1
Bone: cortical tissue density1.72.34.0-0.4-1.2-1.5-1.7-1.5-1.6-1.7-2.0
Condit. Reinf. active minus inactive responses0.50.60.80.40.80.80.80.80.90.80.7
Condit. Reinf. active-inactive response ratio0.70.80.90.50.90.90.90.91.00.90.9
Condit. Reinf. active responses1.11.41.80.71.21.21.21.21.31.21.1
Condit. Reinf. inactive responses0.10.10.3-0.10.10.10.20.20.30.20.6
Incentive salience index mean1.82.22.60.91.51.61.61.61.61.61.4
Condit. Reinf. lever presses1.82.52.91.01.61.61.71.71.71.71.5
Condit. Reinf. active minus inactive responses0.20.31.4-0.8-0.10.10.40.20.30.41.2
Condit. Reinf. active-inactive response ratio0.10.10.6-0.8-0.3-0.20.0-0.2-0.00.00.6
Condit. Reinf. active responses0.20.20.7-0.20.20.30.50.40.50.50.8
Condit. Reinf. inactive responses0.40.50.60.70.80.80.70.70.70.70.4
Condit. Reinf. lever presses0.60.82.5-1.6-1.1-0.9-0.6-0.8-0.7-0.60.5
Condit. Reinf. lever reinforcers received0.10.20.8-0.50.00.10.30.20.30.30.9
Conditioned reinforcement - actives1.42.35.7-0.31.01.31.81.41.51.72.4
Conditioned reinforcement - inactives0.10.10.10.20.30.30.30.30.30.30.3
Conditioned locomotion0.60.81.7-0.00.60.81.20.90.90.91.3
Patch foraging indifference point 0 sec0.30.50.70.30.60.70.80.70.80.80.8
Patch foraging indifference point AUC0.20.30.3-0.4-0.6-0.6-0.5-0.6-0.6-0.6-0.5
Delay disc. indifference point, 0s delay0.50.51.6-1.3-0.8-0.6-0.7-0.7-0.7-0.6-0.0
Delay disc. indifference point, 16s delay0.91.01.40.41.01.00.91.11.01.11.2
Delay disc. indifference point, 2s delay0.10.10.2-0.4-0.3-0.2-0.3-0.3-0.3-0.3-0.1
Delay disc. indifference point, 24s delay0.20.20.4-0.6-0.5-0.6-0.6-0.4-0.4-0.4-0.2
Delay disc. indifference point, 4s delay0.00.00.1-0.2-0.00.1-0.00.00.10.10.3
Delay disc. indifference point, 8s delay0.00.10.3-0.5-0.2-0.1-0.1-0.1-0.1-0.00.3
Indifference point function ln k0.30.60.70.50.80.80.80.80.80.80.8
Indifference point function log k0.30.60.70.50.80.80.80.80.80.80.8
Patch foraging total patch changes 0 sec0.20.50.60.40.60.70.70.70.70.80.7
Patch foraging total patch changes 12 sec0.91.21.4-0.7-1.1-1.2-1.2-1.2-1.2-1.1-1.0
Patch foraging total patch changes 18 sec0.20.30.40.30.50.50.70.60.60.60.6
Patch foraging total patch changes 24 sec0.71.31.50.91.11.11.21.11.21.20.9
Patch foraging total patch changes 6 sec0.10.10.5-0.5-0.1-0.00.20.10.20.20.7
Patch foraging time to switch 0 sec0.71.42.4-0.4-1.0-1.2-1.4-1.2-1.2-1.3-1.5
Patch foraging water rate 0 sec1.43.03.51.31.81.81.91.81.81.91.5
Patch foraging water rate 12 sec1.63.34.20.91.71.82.01.91.92.02.0
Patch foraging water rate 18 sec0.00.10.20.50.20.2-0.10.10.1-0.1-0.3
Patch foraging water rate 24 sec0.10.10.40.60.40.30.20.30.30.2-0.2
Patch foraging water rate 6 sec1.21.72.11.01.31.31.41.41.41.41.2
Seeking ratio, delayed vs. immediate footshock2.32.83.80.71.51.72.01.71.71.81.9
Distance traveled before self-admin0.20.30.70.80.60.60.40.50.50.40.1
Distance traveled after self-admin1.01.21.41.01.11.21.11.11.21.10.8
Extensor digitorum longus weight1.45.46.72.32.62.52.42.52.42.31.4
Bone: elastic displacement0.30.41.31.10.70.60.40.50.40.3-0.4
Bone: elastic work0.20.20.40.60.60.50.50.50.50.40.2
Bone: endosteal estimation0.10.20.3-0.4-0.6-0.4-0.5-0.5-0.4-0.4-0.2
Bone: endosteal perimeter0.40.91.7-1.3-1.2-0.9-0.8-1.0-0.9-0.8-0.0
Epididymis fat weight0.10.41.0-1.0-0.8-0.8-0.6-0.7-0.6-0.5-0.0
Delta time in closed arm before/after self-admin0.00.00.0-0.2-0.1-0.10.0-0.0-0.00.00.1
Delta time in open arm before/after self-admin0.10.10.20.00.20.30.40.30.30.30.4
Diff in mean of infusions in LGA sessions0.10.10.6-0.8-0.3-0.10.1-0.10.00.00.6
Delay discount exponential model param0.10.10.50.70.30.20.20.20.20.1-0.3
Extinction: sum of active levers before priming0.50.52.01.40.90.70.40.70.50.4-0.4
Active lever presses in extinction session 61.31.32.80.00.81.11.21.11.31.21.7
Bone: final force0.10.10.3-0.5-0.3-0.2-0.3-0.3-0.2-0.20.1
Bone: final moment0.00.10.3-0.5-0.2-0.1-0.1-0.1-0.1-0.00.3
Food consumed during 24 hour testing period0.50.72.7-1.5-0.4-0.10.3-0.00.20.31.6
Glucose0.10.10.6-0.40.00.10.30.20.30.30.8
Heart weight1.93.04.32.12.01.81.61.81.81.60.8
Delay discount hyperbolic model param0.10.10.50.70.40.20.30.20.20.2-0.2
Intermittent access intake day 1-15 change0.30.61.3-0.00.50.71.00.70.80.91.2
Intermittent access intake escalation0.30.71.10.30.70.81.00.80.90.91.0
Intermittent access intake escalation 20.20.20.30.10.30.40.60.40.40.40.5
Intermitt. access day 1 inactive lever presses0.51.82.50.51.21.31.41.31.51.61.6
Intermitt. access day 15 inactive lever presses0.51.01.31.01.11.10.91.11.11.00.6
Intermitt. access escalation Index0.10.10.30.60.20.0-0.3-0.00.0-0.0-0.5
Intermittent access day 1 total infusions0.00.10.30.60.20.1-0.00.0-0.1-0.2-0.5
Intermittent access day 15 total infusions0.40.50.70.80.80.70.80.80.70.70.4
Intermittent access terminal intake (last 3 days)0.10.10.20.40.40.30.40.40.30.30.1
Intermittent access total infusions0.10.10.40.60.30.20.20.20.10.1-0.2
Intermittent access day 1 locomotion0.00.00.20.40.20.10.10.10.0-0.1-0.3
Intermittent access day 15 total locomotion0.10.20.6-0.30.10.30.60.40.40.40.8
Intermittent access total locomotion0.10.10.40.60.40.30.30.30.20.1-0.1
Intermittent access standard deviation1.42.93.70.91.61.71.91.71.91.91.8
Left kidney weight5.023.327.52.94.75.05.25.15.25.24.9
Right kidney weight3.214.517.02.63.93.94.14.04.14.13.5
Cocaine induced anxiety0.81.22.91.71.41.10.81.11.00.80.3
Post-drug Anxiety1.81.95.02.21.71.40.91.41.21.00.2
Baseline Anxiety0.10.10.20.20.30.30.10.30.30.40.3
Tail length0.00.00.00.1-0.0-0.1-0.0-0.1-0.1-0.1-0.1
Length with tail0.10.50.80.30.60.70.80.70.80.80.9
Length without tail1.13.75.80.61.61.82.11.92.12.12.4
Times rat made contact with spout0.40.51.9-1.0-0.00.20.50.30.30.51.4
Lifetime Intake0.00.00.00.10.00.00.10.0-0.0-0.0-0.1
Liver weight, left0.20.30.8-0.9-0.7-0.6-0.4-0.6-0.6-0.50.1
Liver weight, right0.20.40.9-0.9-0.8-0.7-0.4-0.6-0.7-0.6-0.0
Locomotor activity0.30.41.8-1.3-0.6-0.2-0.0-0.3-0.1-0.11.0
Locomotor testing distance0.30.52.1-1.2-0.30.10.40.10.30.41.4
Locomotor testing rearing0.30.72.9-1.7-0.6-0.20.1-0.20.00.21.4
Locomotion in novel chamber2.53.26.00.21.31.72.01.71.82.02.5
Locomotion in novel chamber post-restriction0.50.72.31.51.00.90.60.80.70.6-0.2
Fecal boli incidents, locomotor time 10.10.10.7-0.8-0.3-0.20.0-0.2-0.10.00.6
Change in fecal boli incidents, locomotor task0.30.30.5-0.6-0.7-0.6-0.5-0.6-0.6-0.6-0.5
Time >=10cm from walls, locomotor time 10.80.92.50.5-0.5-0.7-1.0-0.8-1.0-1.0-1.6
Bouts of movement, locomotor time 10.91.01.4-1.0-1.2-1.1-0.9-1.1-1.0-0.9-0.7
Total resting periods, locomotor time 10.50.60.9-0.7-0.9-0.8-0.7-0.8-0.8-0.7-0.6
Rest time, locomotor task time 10.20.20.6-0.8-0.6-0.5-0.2-0.4-0.3-0.30.1
Distance moved, locomotor task time 10.20.20.80.90.20.2-0.3-0.1-0.1-0.3-0.8
Vertical activity count, locomotor time 10.20.40.60.60.60.80.60.60.70.60.5
Time >=10cm from walls, locomotor time 20.10.10.40.60.30.20.00.20.00.0-0.3
Bouts of movement, locomotor time 20.30.41.30.4-0.3-0.6-0.4-0.5-0.7-0.7-1.1
Total resting periods, locomotor time 20.20.41.10.2-0.3-0.7-0.4-0.5-0.7-0.7-1.0
Rest time, locomotor task time 20.20.30.7-0.8-0.6-0.7-0.3-0.5-0.5-0.4-0.1
Distance moved, locomotor task time 20.91.01.51.21.11.21.01.01.00.90.5
Vertical activity count, locomotor time 21.31.72.30.71.21.41.51.21.51.41.5
Light reinforcement 10.20.41.01.00.80.70.50.70.60.50.0
Light reinforcement 21.32.02.51.31.61.61.41.51.51.51.0
Bone: marrow area0.10.10.3-0.3-0.5-0.3-0.4-0.4-0.3-0.3-0.2
Bone: maximum diameter0.10.20.30.50.50.60.40.50.50.50.3
Bone: maximum force0.00.00.2-0.4-0.2-0.1-0.2-0.1-0.1-0.10.2
Bone: maximum moment0.00.00.2-0.4-0.10.0-0.00.00.10.10.4
Mean time between licks in bursts1.12.83.6-1.8-1.9-1.8-1.6-1.8-1.7-1.6-0.8
Mean num. licks in bursts0.20.31.3-0.8-0.20.10.40.10.20.41.1
Cd content in liver0.60.70.8-0.7-0.9-0.9-0.9-0.9-0.9-0.9-0.7
Co content in liver0.10.10.3-0.5-0.3-0.3-0.2-0.3-0.2-0.20.1
Cu content in liver1.11.33.9-2.0-1.4-1.1-0.7-1.1-0.9-0.70.5
Fe content in liver0.80.91.51.21.11.10.91.01.00.90.3
K content in liver1.41.34.0-2.0-1.4-1.1-0.7-1.0-0.9-0.70.6
Mg content in liver0.80.83.4-1.3-0.20.20.60.30.40.61.8
Mn content in liver0.20.20.3-0.2-0.4-0.5-0.6-0.5-0.5-0.5-0.6
Na content in liver0.70.71.0-1.0-1.0-0.9-0.8-0.9-0.9-0.8-0.3
Rb content in liver0.20.20.7-0.8-0.5-0.4-0.2-0.4-0.3-0.20.4
Se content in liver0.30.41.0-1.0-0.7-0.6-0.5-0.6-0.5-0.40.2
Sr content in liver0.00.00.00.10.10.00.00.00.00.0-0.1
Zn content in liver1.51.73.7-1.9-1.5-1.4-1.1-1.3-1.2-1.10.0
Bone: minimum diameter0.30.52.2-0.8-0.10.30.50.30.50.61.5
Time in familiar zone, hab. session 10.30.30.7-0.0-0.4-0.6-0.6-0.6-0.5-0.7-0.8
Time in novel zone, hab. session 10.20.20.5-0.7-0.5-0.3-0.3-0.3-0.5-0.20.3
Total zone transitions, hab. session 10.10.10.50.60.40.2-0.10.10.0-0.1-0.7
Total locomotion distance, hab. session 10.60.81.91.41.10.90.70.90.90.7-0.2
Locomotion velocity, hab. session 10.40.51.31.10.90.70.50.70.70.5-0.3
Time in familiar zone, hab. session 21.01.12.5-1.6-1.2-1.1-0.8-1.0-0.9-0.90.1
Time in novel zone, hab. session 20.30.30.91.00.60.50.40.50.30.4-0.3
Total zone transitions, hab. session 20.10.10.4-0.6-0.2-0.20.0-0.10.0-0.00.4
Total locomotion distance, hab. session 20.20.30.50.20.50.50.60.60.70.60.6
Locomotion velocity, hab. session 20.30.50.70.30.70.60.80.70.80.70.7
Novel to familiar place preference ratio0.91.02.7-0.20.60.91.10.90.81.11.7
Novelty place preference0.50.51.5-0.10.40.70.80.70.50.81.2
Time in novel zone, NPP test0.30.41.1-0.20.30.50.60.50.40.71.1
Total zone transitions, NPP test0.91.31.81.11.21.21.11.21.41.10.6
Total locomotion distance, NPP test1.01.41.91.01.31.21.21.31.41.20.8
Locomotion velocity, NPP test1.62.22.91.21.61.61.61.61.71.51.1
Intraocular pressure0.10.20.6-0.10.30.40.50.40.50.50.8
Delta distance traveled before/after self-admin1.11.11.60.41.01.01.21.11.11.21.3
Delta ambulatory time before/after self-admin0.60.81.20.30.80.91.00.90.91.01.1
Parametrial fat weight0.00.00.10.2-0.0-0.0-0.1-0.1-0.0-0.1-0.3
Pavlov. Cond. lever latency2.22.73.5-1.4-1.9-1.8-1.7-1.8-1.7-1.7-1.0
Pavlov. Cond. magazine entry latency0.20.30.4-0.5-0.6-0.6-0.5-0.6-0.6-0.6-0.4
Pavlov. Cond. change in total contacts0.00.00.10.10.30.20.20.20.20.20.1
Pavlov. Cond. index score0.40.50.60.50.80.80.80.80.70.70.5
Pavlov. Cond. latency score0.50.60.80.50.90.90.90.90.80.80.6
Pavlov. Cond. lever contacts1.62.02.51.31.61.51.51.61.41.40.8
Pavlov. Cond. magazine entry number0.20.20.40.30.50.50.50.50.60.50.5
Pavlov. Cond. intertrial magazine entries0.50.51.9-0.40.30.50.80.50.80.71.4
Pavlov. Cond. lever-magazine prob. diff.0.50.60.80.60.80.90.90.90.80.80.7
Pavlov. Cond. response bias0.10.20.30.50.50.50.40.50.30.40.0
Pavlov. Cond. lever latency0.60.93.51.91.00.70.20.60.40.2-1.2
Pavlov. Cond. magazine entry latency2.53.07.7-2.8-2.1-1.8-1.3-1.7-1.5-1.30.4
Pavlov. Cond. change in total contacts0.81.34.7-2.2-1.3-1.0-0.5-0.9-0.7-0.51.1
Pavlov. Cond. index score1.82.57.8-2.8-1.9-1.5-1.0-1.4-1.2-1.00.9
Pavlov. Cond. latency score1.72.37.3-2.7-1.8-1.4-0.9-1.3-1.1-0.90.9
Pavlov. Cond. lever contacts0.50.72.9-1.7-1.0-0.7-0.3-0.6-0.5-0.31.0
Pavlov. Cond. magazine entry number3.74.59.33.12.62.21.82.22.01.80.1
Pavlov. Cond. intertrial magazine entries0.30.41.61.30.70.40.10.30.20.1-0.9
Pavlov. Cond. lever-magazine prob. diff.2.12.88.8-3.0-2.0-1.6-1.0-1.5-1.3-1.01.0
Pavlov. Cond. response bias1.31.85.4-2.3-1.6-1.3-0.9-1.2-1.1-0.90.7
Time in closed arm before self-admin0.30.30.80.1-0.3-0.5-0.7-0.5-0.6-0.6-0.9
Time in closed arm after self-admin0.10.10.40.3-0.1-0.3-0.4-0.3-0.3-0.4-0.6
Time in open arm before self-admin0.20.20.8-0.9-0.5-0.2-0.0-0.2-0.1-0.00.6
Time in open arm after self-admin0.60.61.4-0.00.50.70.90.70.80.91.2
Bone: periosteal estimation0.20.50.60.40.60.80.70.70.80.80.8
Bone: periosteal perimeter0.00.10.3-0.3-0.10.10.20.10.20.20.5
Bone: post-yield work0.10.10.1-0.3-0.4-0.2-0.3-0.3-0.3-0.2-0.1
Progressive ratio test 1 active lever presses0.81.01.10.91.11.01.01.11.01.00.7
Progressive ratio test 1 breakpoint0.81.01.21.01.11.11.11.11.01.00.7
Progressive ratio test 1 inactive lever presses0.50.70.80.80.90.80.80.90.90.90.5
Progressive ratio test 2 active lever presses0.60.71.00.80.90.91.00.90.80.70.5
Progressive ratio test 2 breakpoint0.70.81.01.01.01.01.01.00.80.70.4
Progressive ratio test 2 inactive lever presses0.10.10.20.10.20.30.50.30.30.30.2
Incentive Sensitization - Responses0.00.00.00.00.00.10.20.1-0.0-0.0-0.0
Incentive Sensitization - Breakpoint0.00.00.10.10.10.20.30.20.10.00.0
Sum of active levers in priming session hrs 5-60.40.41.11.10.70.60.40.60.50.4-0.1
Progressive ratio0.20.20.50.10.40.50.50.40.50.60.7
Food seeking constrained by brief footshock2.53.13.8-0.9-1.6-1.8-2.0-1.8-1.9-1.9-1.9
Seeking ratio, punishment vs. effort2.43.44.5-0.9-1.7-1.9-2.0-1.9-2.0-2.1-2.1
Retroperitoneal fat weight0.10.30.4-0.2-0.5-0.5-0.6-0.5-0.6-0.6-0.6
Reaction time number correct0.10.20.91.00.50.2-0.00.20.20.0-0.6
Reaction time mean minus median0.51.35.0-2.2-1.3-1.1-0.7-0.9-0.7-0.40.9
Reaction time mean minus median AUC0.41.03.5-1.9-1.1-1.0-0.7-0.8-0.7-0.50.6
Reaction time num false alarms0.60.93.0-0.50.40.61.10.70.81.01.7
Reaction time num false alarms AUC1.11.74.9-0.40.71.01.51.11.21.42.2
Reaction time trials correct on left0.10.20.91.00.50.2-0.00.20.20.0-0.6
Reaction time trials on left0.10.20.70.80.40.2-0.00.20.20.0-0.6
Reaction time mean0.71.23.7-1.9-1.3-1.1-0.8-1.0-0.8-0.60.4
Reaction time mean AUC0.81.23.2-1.8-1.3-1.2-0.9-1.1-1.0-0.80.1
Median of all reaction times0.60.92.2-1.5-1.1-1.0-0.8-0.9-0.8-0.70.1
Reaction time omissions0.50.73.1-1.8-0.8-0.50.0-0.3-0.20.11.4
Reaction time false alarm rate1.21.75.7-0.70.50.91.51.01.11.32.4
Reaction time premature initiation rate0.30.41.0-1.0-0.7-0.5-0.6-0.5-0.5-0.40.2
Reaction time premature initiations0.10.20.4-0.5-0.5-0.5-0.7-0.5-0.5-0.5-0.3
Std. dev. reaction times0.71.24.9-2.2-1.2-0.9-0.5-0.8-0.6-0.31.1
Reaction time trials completed0.10.20.70.80.40.2-0.00.20.20.0-0.6
Reaction time trials AUC0.10.20.80.90.50.30.20.30.40.2-0.4
Run reversals in cocaine runway, females0.30.30.8-0.9-0.7-0.5-0.3-0.5-0.5-0.40.0
Run reversals in cocaine runway, males1.51.53.6-0.20.81.11.41.21.31.41.9
Latency to leave start box in cocaine runway1.21.42.01.41.31.21.21.21.11.10.5
Latency to leave start box in cocaine runway, F2.12.43.71.91.81.71.61.61.51.40.7
Latency to leave start box in cocaine runway, M0.20.20.8-0.9-0.6-0.4-0.3-0.4-0.3-0.20.1
Std. dev. time between licks in bursts2.53.43.9-1.6-1.9-2.0-1.9-2.0-1.9-1.9-1.4
Total sessions with >9 infusions0.10.10.3-0.5-0.3-0.2-0.1-0.2-0.3-0.20.2
Short access day 1 total inactive lever presses1.62.12.71.21.51.51.61.51.61.51.2
Short access day 10 total inactive lever presses0.10.20.40.20.40.40.50.50.60.60.5
Short access day 1 total infusions0.00.00.00.20.10.10.10.10.0-0.0-0.0
Short access day 10 total infusions0.30.41.31.20.80.60.50.60.50.4-0.1
Short access total infusions0.00.00.1-0.2-0.2-0.2-0.2-0.2-0.2-0.2-0.2
Short access day 1 locomotion0.70.81.9-0.00.60.91.10.90.91.01.4
Short access day 10 total locomotion0.40.70.90.70.90.90.90.90.90.80.8
Short access total locomotion0.00.00.10.0-0.1-0.1-0.1-0.2-0.2-0.3-0.2
One hour access (0.3 mA shock)0.10.10.2-0.4-0.4-0.3-0.2-0.3-0.4-0.4-0.2
Compulsive drug intake0.60.71.3-0.0-0.6-0.7-1.0-0.8-0.8-0.9-1.2
One hour access (shock baseline)0.81.21.90.40.91.11.41.11.11.11.3
Social response proportion0.30.30.6-0.8-0.7-0.5-0.6-0.6-0.6-0.4-0.1
Social responses1.41.92.4-1.3-1.6-1.3-1.4-1.4-1.5-1.4-0.9
Social time0.00.00.2-0.3-0.20.00.20.00.10.10.4
Soleus weight2.88.49.71.92.93.03.13.13.13.12.7
Bone: stiffness0.00.00.1-0.4-0.2-0.1-0.2-0.2-0.1-0.10.1
Tibialis anterior weight4.615.519.34.14.44.24.04.24.04.02.2
Time to tail flick, vehicle, before self-admin2.52.63.21.71.81.71.61.81.61.61.0
Time to tail flick, vehicle, after self-admin0.70.91.91.41.21.00.81.00.90.80.3
Time to tail flick, test, before self-admin4.44.59.53.12.62.31.72.22.01.80.5
Time to tail flick, test, after self-admin1.41.52.31.51.41.31.11.21.31.10.6
Delta time to tail flick, vehicle, before/after SA0.00.00.10.30.20.20.00.10.10.1-0.1
Delta time to tail flick, test, before/after SA0.50.51.8-1.4-0.9-0.7-0.4-0.7-0.5-0.40.3
Tibia length0.10.30.50.30.60.60.50.60.70.60.6
Ambulatory time before self-admin0.00.10.20.50.30.30.20.20.30.20.0
Ambulatory time after self-admin0.60.70.90.90.91.00.80.90.90.80.6
Bone: tissue strength1.21.21.8-1.3-1.3-1.2-1.1-1.2-1.1-1.0-0.4
Total heroin consumption0.30.30.5-0.4-0.6-0.6-0.7-0.6-0.6-0.7-0.5
Bone: trabecular number0.71.21.4-0.8-1.1-1.1-1.2-1.1-1.2-1.2-1.0
Bone: trabecular spacing1.31.82.01.21.41.41.41.41.41.40.9
Bone: trabecular thickness0.70.91.2-1.1-1.0-1.0-0.9-1.0-1.0-0.9-0.4
Bone: trabecular tissue density0.10.20.80.60.1-0.1-0.4-0.2-0.3-0.4-0.9
Water consumed over 24 hours0.60.82.8-0.60.40.60.90.70.80.91.7
Number of responses in last shaping day2.02.23.20.61.31.51.81.51.51.51.7