Hub : Genes

Krt26

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr10_84289463_84292220 0.02 0.02 2.0e-03 0.02 0.02 0.02 0.02 1.8e-03 1.1e-03 1.7e-03 2.4e-03
2 pVTA intron excision ratio chr10_84282313_84283873 0.38 0.13 3.4e-13 0.3 0.27 0.31 0.3 1.3e-13 6.0e-12 4.8e-14 9.6e-14
3 LHb gene expression Krt26 0.27 0.14 5.0e-04 0.1 0.14 0.08 0.09 2.0e-03 2.9e-04 5.6e-03 4.1e-03
4 pVTA mRNA stability Krt26 0.09 0.06 1.6e-03 0.03 0.02 0.02 0.02 2.0e-02 4.5e-02 4.8e-02 3.7e-02
5 BLA mRNA stability Krt26 0.06 0.04 5.2e-03 0.04 0.04 0.04 0.04 3.8e-03 3.1e-03 3.9e-03 4.5e-03
6 NAcc intron excision ratio chr10_84282313_84283873 0.1 0.05 1.9e-12 0.11 0.09 0.1 0.1 2.1e-12 2.0e-10 3.3e-11 1.1e-11
7 NAcc mRNA stability Krt26 0.04 0.02 1.0e-04 0.03 0.03 0.03 0.03 9.8e-05 3.1e-04 1.7e-04 1.4e-04
8 pVTA intron excision ratio chr10_84282313_84286397 0.45 0.12 5.6e-17 0.34 0.32 0.31 0.35 1.4e-15 1.5e-14 3.5e-14 5.2e-16
9 Brain mRNA stability Krt26 0.13 0.06 4.3e-09 0.11 0.09 0.09 0.1 1.5e-10 7.5e-09 4.6e-09 1.6e-09
10 LHb intron excision ratio chr10_84282313_84286397 0.42 0.14 1.7e-06 0.22 0.25 0.24 0.02 6.4e-06 1.0e-06 2.1e-06 1.3e-01
11 LHb intron excision ratio chr10_84282313_84283873 0.14 0.09 9.0e-03 0.07 0.06 0.06 0.03 1.1e-02 1.2e-02 1.8e-02 5.5e-02
12 NAcc intron excision ratio chr10_84283931_84286397 0.06 0.04 1.6e-07 0.04 0.05 0.05 0.04 3.6e-05 9.7e-07 3.2e-06 5.5e-06
13 PL intron excision ratio chr10_84283931_84286397 0.04 0.03 8.3e-05 0.03 0.03 0.03 0.03 2.9e-04 3.2e-04 8.2e-04 6.6e-04
14 Eye alternative TSS XM_039086530.1 0.63 0.15 1.3e-04 0.05 0.05 0.01 0.03 6.6e-02 6.4e-02 1.9e-01 1.0e-01
15 IL mRNA stability Krt26 0.45 0.15 5.6e-04 0.11 0.15 0.07 0.01 1.6e-03 2.1e-04 8.9e-03 2.1e-01
16 PL mRNA stability Krt26 0.08 0.04 2.0e-06 0.04 0.05 0.05 0.05 4.6e-05 3.8e-06 2.9e-06 6.4e-06
17 PL intron excision ratio chr10_84282313_84283873 0.1 0.05 5.6e-09 0.07 0.07 0.07 0.06 7.5e-08 1.7e-08 3.8e-08 1.3e-07
18 LHb isoform ratio NM_001008823.2 0.26 0.11 1.8e-05 0.16 0.22 0.14 0.18 1.1e-04 6.5e-06 3.0e-04 4.0e-05
19 LHb isoform ratio XM_039086530.1 0.25 0.11 2.4e-05 0.17 0.21 0.15 0.16 9.5e-05 1.2e-05 1.7e-04 1.4e-04
20 LHb alternative TSS XM_039086530.1 0.24 0.11 1.2e-04 0.04 0.16 0.1 0.12 4.6e-02 1.2e-04 2.8e-03 9.2e-04
21 LHb alternative TSS NM_001008823.2 0.25 0.12 1.0e-04 0.05 0.17 0.11 0.12 2.3e-02 9.4e-05 1.7e-03 8.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bone: apparent density1.72.96.1-1.62.02.02.2-2.12.52.41.81.92.11.81.5-1.1-1.2-1.51.8-1.8-0.30.40.2-0.2
Area under the delay curve1.01.02.6-0.80.7-0.10.4-0.40.90.90.70.70.60.71.3-0.9-1.2-1.21.6-0.8-1.41.41.5-1.5
BMI with tail1.03.47.72.8-2.3-1.6-1.91.6-1.6-1.8-1.8-1.8-1.3-1.7-2.11.72.20.4-1.90.82.1-2.0-1.91.9
BMI without tail0.10.30.60.5-0.4-0.3-0.50.5-0.5-0.8-0.6-0.6-0.6-0.5-0.60.40.50.6-0.40.50.5-0.5-0.50.5
Body weight1.77.219.74.4-3.5-3.2-3.12.8-2.2-2.4-2.8-2.8-1.9-2.5-2.83.03.3-0.1-2.11.42.6-2.5-2.22.2
Weight adjusted by age0.50.54.90.40.1-0.20.7-0.20.60.60.60.71.10.50.8-0.1-0.0-2.20.8-1.0-0.20.20.4-0.5
Bone surface0.40.71.20.30.40.71.0-0.71.01.00.70.81.10.8-0.10.60.4-1.10.5-0.81.0-1.0-1.01.0
Bone volume0.61.02.00.20.51.21.1-1.11.31.20.90.91.40.9-0.10.50.5-1.20.3-1.11.3-1.3-1.31.4
Breakpoint value in progressive ratio session0.20.30.9-0.40.50.70.7-0.60.50.50.60.50.60.60.3-1.0-0.3-0.60.3-0.5-0.00.00.0-0.0
Number of licking bursts0.40.51.80.3-0.01.10.3-0.50.10.2-0.2-0.20.7-0.0-0.5-0.10.8-0.6-0.4-0.31.3-1.3-1.31.3
Context. condit. distance diff. score0.91.13.80.2-0.3-2.0-0.81.2-0.6-0.6-0.4-0.4-1.6-0.50.2-0.5-0.71.00.80.7-1.51.51.6-1.6
Locomotion velocity, session 10.20.20.90.6-0.10.2-0.2-0.2-0.10.00.00.00.20.1-0.50.00.5-0.3-0.6-0.41.0-0.9-0.90.9
Locomotion distance, session 10.81.13.11.8-1.3-0.7-1.30.7-0.5-0.6-0.7-0.7-0.1-0.8-1.10.91.4-0.8-0.90.01.4-1.4-1.21.3
Locomotion velocity, session 20.10.10.20.00.4-0.20.30.00.00.10.0-0.00.0-0.00.2-0.4-0.1-0.50.4-0.2-0.30.30.3-0.3
Locomotion distance, session 20.30.43.10.7-0.40.2-0.3-0.10.40.4-0.1-0.10.9-0.3-0.00.20.7-1.80.0-0.60.7-0.7-0.60.6
Locomotion velocity, session 30.20.20.8-0.50.70.00.5-0.10.10.10.50.5-0.10.20.5-0.9-0.5-0.20.3-0.1-0.80.70.7-0.8
Locomotion distance, session 30.10.10.20.4-0.2-0.3-0.20.4-0.4-0.4-0.0-0.0-0.2-0.3-0.2-0.10.4-0.3-0.10.30.1-0.1-0.10.0
Stereotopy head waving bouts, day 32.22.64.6-2.12.11.21.9-1.71.61.51.81.81.11.81.8-1.6-2.0-0.41.3-1.4-1.51.51.4-1.3
Stereotopy head waving duration, day 30.40.50.9-0.70.80.20.9-0.80.80.90.90.90.50.80.8-0.2-0.9-0.10.5-0.8-0.60.60.6-0.6
Locomotion velocity, session 71.41.52.91.6-1.3-0.5-0.80.9-1.0-1.0-1.1-1.0-0.5-1.1-1.41.61.70.2-1.40.91.6-1.6-1.51.5
Locomotion distance, session 71.31.72.81.6-1.7-1.1-1.21.6-1.4-1.4-1.4-1.4-1.0-1.5-1.31.71.60.4-0.91.60.8-1.0-0.80.8
Stereotopy head waving bouts, day 71.21.42.5-1.11.20.91.0-1.41.41.41.31.31.41.21.3-1.4-1.2-1.21.1-1.6-0.60.70.6-0.6
Stereotopy head waving duration, day 71.41.73.6-1.31.31.01.0-1.61.51.61.41.31.41.41.5-1.7-1.4-1.31.0-1.9-0.80.90.8-0.8
Locomotion velocity, session 82.53.08.32.2-1.9-2.9-2.42.4-2.1-2.0-2.0-2.1-2.4-2.2-1.40.91.30.9-0.91.50.1-0.10.1-0.1
Locomotion distance, session 80.20.31.31.0-0.7-1.2-0.90.7-0.4-0.4-0.3-0.3-0.4-0.5-0.1-0.30.3-0.70.20.0-0.10.20.3-0.3
Degree of sensitization distance2.32.34.11.6-1.9-1.7-1.71.9-1.6-1.6-2.0-2.0-1.5-2.0-1.41.71.41.1-0.81.80.6-0.6-0.50.5
Degree of sensitization stereotypy1.21.32.5-1.11.21.10.9-1.41.21.41.21.11.51.01.3-1.5-1.1-1.41.1-1.6-0.60.60.6-0.6
Conditioned locomotion0.40.51.2-0.80.70.30.3-0.70.90.90.30.30.60.30.8-1.1-0.9-0.31.1-0.7-0.70.70.7-0.7
Cocaine response after cond. corrected1.51.75.5-0.70.91.11.0-1.41.61.51.71.71.91.41.4-1.0-0.8-2.31.2-1.8-0.30.30.4-0.3
Cocaine response after cond. not corrected1.41.65.7-0.60.81.01.1-1.41.71.71.51.52.01.21.3-0.5-0.6-2.41.1-1.7-0.20.20.3-0.3
Cocaine response before conditioning0.10.21.00.1-0.2-0.30.30.4-0.10.1-0.7-0.7-0.3-0.6-0.21.00.20.5-0.10.7-0.0-0.1-0.0-0.0
Saline control response0.10.11.40.6-0.5-0.4-0.20.20.30.2-0.0-0.00.4-0.20.10.20.3-1.20.3-0.40.1-0.10.0-0.0
Bone: connectivity density2.33.56.8-2.02.22.22.6-2.22.62.62.02.02.32.01.7-1.3-1.5-1.52.1-1.8-0.60.60.5-0.5
Bone: cortical apparent density1.62.27.8-2.82.22.01.6-1.70.91.01.41.40.71.71.3-1.4-1.91.10.7-0.5-1.31.31.0-0.9
Bone: cortical area0.00.10.2-0.10.30.40.2-0.20.30.2-0.1-0.10.20.0-0.20.20.10.20.2-0.00.4-0.4-0.40.4
Bone: cortical porosity0.80.82.0-0.20.71.01.2-1.11.11.11.31.21.21.40.4-0.1-0.2-1.10.4-1.30.5-0.5-0.50.5
Bone: cortical porosity0.80.82.3-0.10.70.71.1-1.01.21.21.21.21.31.20.6-0.1-0.2-1.50.5-1.40.4-0.3-0.30.3
Bone: cortical thickness0.81.22.4-1.51.50.81.0-1.01.31.30.70.60.70.61.3-1.4-1.4-0.21.4-0.7-1.31.21.2-1.1
Bone: cortical thickness6.98.011.1-3.23.31.92.7-2.73.03.12.72.62.42.83.3-3.1-3.3-2.13.1-2.6-2.72.72.6-2.6
Bone: cortical tissue density1.62.17.7-2.82.12.01.6-1.70.91.01.31.40.71.71.3-1.4-1.91.10.6-0.5-1.31.20.9-0.9
Condit. Reinf. active minus inactive responses1.21.42.7-1.61.40.60.7-0.80.80.90.90.80.50.61.4-1.6-1.5-0.31.7-0.7-1.61.61.5-1.5
Condit. Reinf. active-inactive response ratio1.41.53.4-1.71.40.50.8-0.80.91.00.80.70.30.61.3-1.8-1.60.11.7-0.5-1.71.71.6-1.6
Condit. Reinf. active responses0.91.12.3-1.51.50.60.9-0.80.60.60.70.60.40.61.2-1.5-1.3-0.31.3-0.5-1.41.41.3-1.3
Condit. Reinf. inactive responses0.10.10.5-0.10.60.40.7-0.30.1-0.00.30.30.40.50.2-0.3-0.0-0.60.1-0.30.0-0.0-0.00.0
Incentive salience index mean0.91.12.1-1.51.31.01.0-0.80.80.90.80.80.80.71.2-1.3-1.2-0.71.4-0.5-1.21.21.1-1.1
Condit. Reinf. lever presses0.10.10.6-0.30.40.50.8-0.10.20.10.20.20.50.10.30.10.1-0.70.40.2-0.20.00.1-0.1
Condit. Reinf. active minus inactive responses0.30.31.8-0.60.51.30.6-0.70.40.70.60.60.90.30.2-0.20.0-0.60.1-0.30.4-0.4-0.50.5
Condit. Reinf. active-inactive response ratio0.20.21.2-0.10.10.80.5-0.20.20.50.20.20.70.10.20.40.3-1.10.10.00.3-0.4-0.30.3
Condit. Reinf. active responses0.70.94.1-0.90.92.00.9-1.41.01.11.01.01.50.70.3-0.7-0.1-0.90.1-0.80.7-0.6-0.80.8
Condit. Reinf. inactive responses1.01.34.3-1.31.22.11.0-1.81.51.21.21.21.61.10.7-1.2-0.6-0.70.3-1.30.4-0.3-0.50.6
Condit. Reinf. lever presses0.10.20.9-0.50.50.60.2-0.60.60.50.50.40.3-0.10.3-1.0-0.4-0.20.3-0.4-0.10.20.1-0.1
Condit. Reinf. lever reinforcers received0.81.14.1-1.21.12.00.9-1.51.21.21.21.11.40.80.6-1.0-0.4-0.90.3-1.00.3-0.3-0.40.5
Conditioned reinforcement - actives0.00.00.3-0.4-0.40.5-0.3-0.0-0.00.00.00.00.20.1-0.0-0.20.00.2-0.20.4-0.1-0.0-0.00.0
Conditioned reinforcement - inactives0.30.32.7-0.9-0.10.9-0.1-0.2-0.1-0.1-0.2-0.1-0.2-0.1-0.30.6-0.11.7-0.70.80.1-0.2-0.40.4
Conditioned locomotion0.20.20.9-0.1-0.40.9-0.4-0.2-0.3-0.3-0.3-0.30.4-0.3-0.4-0.20.50.0-0.80.20.7-0.8-0.80.8
Patch foraging indifference point 0 sec0.20.30.9-0.90.50.60.20.00.50.30.20.20.10.00.4-0.4-0.40.20.90.8-0.80.60.6-0.7
Patch foraging indifference point AUC0.10.10.20.10.00.30.5-0.30.10.10.20.20.20.2-0.1-0.30.1-0.1-0.3-0.40.5-0.4-0.40.5
Delay disc. indifference point, 0s delay0.70.71.4-1.00.91.00.8-1.01.01.00.90.90.91.20.9-0.8-0.8-0.80.9-0.8-0.50.50.5-0.4
Delay disc. indifference point, 16s delay3.94.08.1-1.71.9-0.41.3-1.01.51.51.61.60.61.52.4-2.5-2.6-1.12.8-1.6-2.82.82.8-2.8
Delay disc. indifference point, 2s delay0.30.41.4-0.50.41.20.4-0.90.70.70.70.71.00.70.3-0.3-0.1-0.80.1-0.70.4-0.4-0.40.4
Delay disc. indifference point, 24s delay0.40.41.20.2-0.2-1.0-0.60.8-0.4-0.4-0.3-0.4-0.6-0.60.3-0.3-0.2-0.30.80.6-1.00.91.0-1.1
Delay disc. indifference point, 4s delay2.72.84.7-1.51.40.71.5-1.41.81.81.71.71.61.82.1-1.3-1.8-2.02.2-1.8-1.61.61.7-1.7
Delay disc. indifference point, 8s delay0.00.00.1-0.10.10.1-0.10.00.10.1-0.2-0.30.1-0.30.10.3-0.0-0.20.30.1-0.20.10.1-0.2
Indifference point function ln k0.30.41.3-0.30.0-0.7-0.30.40.10.1-0.00.0-0.50.10.40.2-0.60.51.20.4-1.11.01.1-1.1
Indifference point function log k0.30.41.3-0.30.0-0.7-0.30.40.10.1-0.00.0-0.50.10.40.2-0.60.51.20.4-1.11.01.1-1.1
Patch foraging total patch changes 0 sec0.10.11.0-0.60.30.4-0.00.30.20.1-0.1-0.1-0.2-0.30.0-0.1-0.00.40.51.0-0.50.30.3-0.4
Patch foraging total patch changes 12 sec1.72.27.8-1.61.62.81.8-2.01.81.61.71.72.11.30.9-1.6-0.6-1.30.1-1.20.3-0.4-0.50.5
Patch foraging total patch changes 18 sec0.20.20.9-0.20.31.00.5-0.20.0-0.00.00.00.1-0.2-0.5-0.00.50.3-0.60.40.7-0.7-0.80.8
Patch foraging total patch changes 24 sec0.91.22.3-1.11.21.41.4-1.31.51.41.21.11.30.80.9-1.5-0.8-1.10.6-1.0-0.30.30.3-0.3
Patch foraging total patch changes 6 sec0.40.51.0-1.00.60.80.8-0.51.00.70.80.80.80.50.8-0.6-0.6-0.80.90.0-0.80.60.7-0.7
Patch foraging time to switch 0 sec0.10.20.8-0.30.20.60.0-0.60.60.50.40.40.60.10.3-0.9-0.2-0.80.0-0.60.00.00.00.0
Patch foraging water rate 0 sec0.00.00.3-0.20.2-0.00.10.1-0.1-0.1-0.2-0.2-0.2-0.00.00.5-0.10.3-0.00.3-0.20.20.2-0.2
Patch foraging water rate 12 sec0.00.00.1-0.20.30.20.1-0.30.30.40.00.0-0.00.1-0.00.1-0.10.3-0.0-0.10.1-0.0-0.10.1
Patch foraging water rate 18 sec0.81.13.2-0.61.00.91.4-1.11.51.41.21.11.51.11.0-0.5-0.6-1.81.1-1.2-0.30.30.3-0.3
Patch foraging water rate 24 sec0.10.20.7-0.40.60.60.8-0.40.40.50.60.60.50.50.20.4-0.1-0.20.2-0.1-0.0-0.0-0.00.0
Patch foraging water rate 6 sec1.01.53.4-1.51.81.51.5-1.41.41.51.11.01.41.01.3-1.2-1.2-1.11.0-1.1-0.80.80.7-0.7
Seeking ratio, delayed vs. immediate footshock0.91.13.4-1.30.5-0.4-0.00.10.10.20.20.1-0.70.10.9-1.3-1.41.11.10.3-1.91.81.7-1.7
Distance traveled before self-admin0.20.21.40.2-0.2-0.30.40.10.30.30.30.30.50.30.50.4-0.0-1.20.6-0.3-0.30.30.5-0.5
Distance traveled after self-admin0.30.31.00.9-0.6-1.0-0.40.7-0.7-0.7-0.6-0.6-0.5-0.6-0.41.00.50.1-0.40.20.2-0.2-0.10.1
Extensor digitorum longus weight5.119.931.25.5-5.6-5.6-5.65.4-4.9-4.9-5.4-5.5-5.0-5.4-4.44.14.13.1-3.24.12.1-2.1-1.81.7
Bone: elastic displacement0.60.61.40.4-0.7-0.1-0.90.7-1.0-0.9-0.9-0.9-0.8-0.5-1.00.50.71.2-1.11.10.6-0.7-0.70.7
Bone: elastic work0.30.41.0-0.40.80.70.7-0.80.80.90.90.80.81.00.4-0.7-0.3-0.50.6-0.80.2-0.1-0.20.2
Bone: endosteal estimation1.53.27.32.7-2.0-1.0-1.21.2-1.1-1.3-1.1-1.1-0.4-1.0-2.02.72.5-0.2-1.50.62.6-2.5-2.42.4
Bone: endosteal perimeter1.43.05.02.1-2.0-0.8-1.51.3-1.5-1.7-1.4-1.3-1.0-1.2-2.22.22.21.0-1.61.22.2-2.2-2.22.2
Epididymis fat weight0.20.51.20.8-0.70.0-0.40.3-0.1-0.2-0.2-0.20.2-0.4-0.71.11.0-0.2-0.90.41.1-1.1-1.01.0
Delta time in closed arm before/after self-admin0.90.92.21.5-1.0-1.5-1.01.1-1.0-1.1-1.1-1.1-1.1-1.1-0.90.80.90.4-0.70.50.5-0.5-0.40.4
Delta time in open arm before/after self-admin0.10.10.2-0.30.3-0.20.2-0.10.10.30.10.1-0.10.20.30.3-0.40.40.2-0.1-0.40.40.4-0.4
Diff in mean of infusions in LGA sessions0.10.10.3-0.20.30.50.3-0.50.40.40.20.10.40.10.1-0.0-0.0-0.20.1-0.30.2-0.2-0.20.2
Delay discount exponential model param1.01.12.90.7-0.60.3-0.40.3-0.8-0.8-0.7-0.6-0.5-0.6-1.30.91.21.2-1.70.71.5-1.5-1.61.6
Extinction: sum of active levers before priming1.11.12.41.6-1.1-0.8-0.70.9-0.8-0.9-1.0-1.0-0.6-1.0-1.31.21.40.3-1.20.61.3-1.3-1.21.2
Active lever presses in extinction session 64.64.411.7-1.11.82.32.6-2.72.62.52.42.43.32.51.8-1.3-1.0-3.41.2-3.00.3-0.1-0.10.2
Bone: final force1.01.63.6-0.21.21.31.6-1.31.71.61.61.61.91.60.6-0.0-0.0-1.90.8-1.40.7-0.7-0.70.7
Bone: final moment0.71.22.9-0.01.01.11.4-1.11.51.41.31.41.71.30.40.20.2-1.70.6-1.20.8-0.8-0.80.8
Food consumed during 24 hour testing period0.50.61.61.0-1.2-0.9-1.30.9-0.7-0.9-0.9-1.0-0.6-0.9-0.70.60.80.2-0.40.60.4-0.4-0.30.3
Glucose0.20.40.8-0.10.40.80.6-0.80.60.70.50.60.60.7-0.20.00.00.1-0.1-0.70.8-0.7-0.80.9
Heart weight2.53.56.02.3-1.9-2.4-2.12.4-2.3-2.2-2.0-2.0-2.2-2.1-1.92.01.81.4-1.22.00.8-0.8-0.70.7
Delay discount hyperbolic model param1.01.02.60.8-0.70.1-0.40.4-0.9-0.9-0.7-0.7-0.6-0.7-1.30.81.11.2-1.60.81.4-1.4-1.51.5
Intermittent access intake day 1-15 change1.11.13.2-1.51.51.71.1-1.81.01.10.90.90.61.00.3-0.7-1.01.1-0.3-1.20.4-0.2-0.50.6
Intermittent access intake escalation1.31.33.7-1.61.71.81.3-1.91.21.31.11.10.81.20.5-1.0-1.20.70.0-1.40.2-0.0-0.30.4
Intermittent access intake escalation 20.50.41.5-0.60.81.20.4-1.10.20.30.20.20.30.3-0.2-0.6-0.20.8-0.7-0.80.8-0.7-0.91.0
Intermitt. access day 1 inactive lever presses4.24.46.0-2.12.21.42.3-2.22.42.42.42.52.22.42.5-1.7-2.2-1.92.2-2.4-1.61.61.6-1.5
Intermitt. access day 15 inactive lever presses2.52.76.1-2.51.92.11.7-2.12.01.91.81.81.61.81.6-1.6-1.9-0.21.3-1.4-1.01.10.9-0.8
Intermitt. access escalation Index0.20.21.00.8-0.0-0.90.30.20.20.20.20.20.10.20.1-0.20.1-1.00.5-0.7-0.00.10.2-0.2
Intermittent access day 1 total infusions0.10.20.7-0.2-0.3-0.10.20.00.20.20.30.30.50.40.60.1-0.3-0.80.6-0.0-0.60.50.6-0.6
Intermittent access day 15 total infusions1.51.72.6-1.61.51.01.5-1.61.51.51.51.51.01.61.3-1.2-1.6-0.21.1-1.4-0.91.00.8-0.8
Intermittent access terminal intake (last 3 days)1.01.11.8-1.41.01.01.1-1.31.21.21.21.31.01.31.1-0.9-1.3-0.30.8-1.2-0.70.70.6-0.6
Intermittent access total infusions0.60.71.1-0.90.60.30.9-0.70.90.91.01.00.71.01.0-0.6-1.0-0.60.9-0.8-0.90.90.9-0.9
Intermittent access day 1 locomotion0.40.41.10.1-0.70.3-0.50.3-0.6-0.6-0.5-0.5-0.3-0.4-0.70.70.51.0-1.10.80.6-0.6-0.70.7
Intermittent access day 15 total locomotion1.41.54.50.0-0.81.0-1.3-0.1-0.9-0.9-0.8-0.8-0.4-0.7-1.40.80.92.0-2.10.81.6-1.6-1.81.8
Intermittent access total locomotion0.30.32.2-0.7-0.01.1-0.3-0.5-0.1-0.2-0.1-0.0-0.00.0-0.40.0-0.01.5-1.00.30.5-0.5-0.70.7
Intermittent access standard deviation1.41.54.4-2.11.81.81.4-1.71.21.21.21.20.81.30.9-1.5-1.50.80.4-1.0-0.50.60.3-0.2
Left kidney weight0.30.92.80.20.9-1.30.00.10.60.50.60.5-0.30.50.8-1.7-0.9-1.01.2-0.9-1.21.31.5-1.4
Right kidney weight0.61.85.2-0.31.10.00.9-1.11.71.51.51.41.41.51.5-1.5-1.1-2.31.5-2.1-0.70.91.0-0.9
Cocaine induced anxiety0.60.77.11.1-0.2-1.00.10.20.30.30.30.20.70.20.6-0.60.2-2.71.1-1.1-0.20.30.6-0.6
Post-drug Anxiety0.80.94.30.10.2-0.80.60.00.60.60.60.60.60.51.2-0.6-0.6-2.11.7-0.8-1.11.21.4-1.4
Baseline Anxiety0.30.33.5-0.90.10.30.00.1-0.2-0.2-0.3-0.2-0.7-0.3-0.20.4-0.31.9-0.30.9-0.40.30.2-0.2
Tail length0.10.31.00.1-0.3-0.9-0.50.50.0-0.2-0.4-0.4-0.3-0.20.4-0.3-0.3-0.30.70.1-0.90.80.9-1.0
Length with tail0.41.56.72.1-1.7-2.6-1.71.7-0.8-0.8-1.3-1.3-1.1-1.1-0.61.31.0-0.60.10.60.00.00.3-0.4
Length without tail0.51.25.22.3-1.6-1.8-1.21.1-0.4-0.2-0.7-0.8-0.3-0.7-0.81.51.4-1.3-0.4-0.11.0-0.9-0.60.6
Times rat made contact with spout0.10.20.6-0.10.00.70.2-0.1-0.3-0.2-0.1-0.10.3-0.2-0.30.70.40.2-0.60.30.5-0.6-0.70.6
Lifetime Intake1.21.42.1-1.10.80.21.2-0.81.21.21.31.30.91.31.4-0.7-1.3-1.01.5-1.0-1.31.31.3-1.3
Liver weight, left0.00.10.2-0.20.20.30.3-0.20.20.30.0-0.00.40.10.3-0.1-0.1-0.50.1-0.2-0.10.10.1-0.2
Liver weight, right3.55.99.8-1.92.31.32.4-2.63.13.12.92.92.52.82.7-2.2-2.4-2.62.4-3.1-1.51.71.7-1.6
Locomotor activity0.81.23.0-0.61.01.71.1-1.41.21.11.21.11.71.30.5-1.1-0.1-1.60.2-1.40.7-0.6-0.70.7
Locomotor testing distance1.01.74.8-1.71.72.21.3-1.81.61.51.41.41.71.31.0-1.4-1.0-0.90.8-1.3-0.10.1-0.00.1
Locomotor testing rearing3.45.310.1-3.22.82.62.5-2.62.62.62.82.82.02.52.3-2.3-2.5-0.91.9-1.8-1.71.61.4-1.4
Locomotion in novel chamber4.55.68.3-2.52.41.62.6-2.12.42.42.52.52.42.52.9-2.1-2.4-2.52.8-2.0-2.22.22.2-2.2
Locomotion in novel chamber post-restriction0.40.42.0-0.3-0.01.40.4-0.70.20.10.30.41.10.6-0.10.50.4-0.6-0.6-0.30.9-0.9-0.90.9
Fecal boli incidents, locomotor time 11.92.13.91.0-1.3-0.3-1.61.0-1.5-1.6-1.6-1.6-1.1-1.7-1.61.81.41.6-2.01.31.3-1.3-1.41.4
Change in fecal boli incidents, locomotor task0.40.31.4-0.20.6-0.00.3-0.40.50.60.70.60.40.60.5-1.2-0.5-0.90.7-0.7-0.40.50.5-0.5
Time >=10cm from walls, locomotor time 10.10.10.4-0.50.1-0.0-0.20.1-0.0-0.0-0.3-0.3-0.4-0.30.1-0.6-0.40.60.20.4-0.60.50.5-0.5
Bouts of movement, locomotor time 10.10.10.40.3-0.2-0.30.30.00.10.1-0.1-0.10.3-0.00.20.50.1-0.60.2-0.30.1-0.00.1-0.0
Total resting periods, locomotor time 10.30.41.41.0-1.0-0.6-0.30.6-0.4-0.5-0.7-0.6-0.1-0.6-0.51.20.8-0.4-0.40.20.6-0.6-0.50.5
Rest time, locomotor task time 10.90.92.80.8-1.10.4-0.10.2-0.5-0.5-0.4-0.30.1-0.2-1.11.71.20.4-1.40.61.5-1.5-1.51.5
Distance moved, locomotor task time 11.51.63.9-0.91.0-0.20.4-0.61.00.91.00.90.50.81.6-1.9-1.5-1.32.0-1.1-1.71.81.8-1.8
Vertical activity count, locomotor time 10.10.10.6-0.00.3-0.2-0.1-0.00.10.10.0-0.0-0.1-0.20.2-0.8-0.2-0.20.3-0.2-0.30.30.3-0.3
Time >=10cm from walls, locomotor time 20.60.62.1-0.70.61.40.8-1.10.90.90.90.91.10.90.3-1.2-0.2-0.50.1-0.70.4-0.4-0.50.5
Bouts of movement, locomotor time 20.80.81.8-0.71.20.41.4-0.71.01.21.11.10.70.90.9-1.3-0.8-0.71.0-0.7-0.70.70.7-0.7
Total resting periods, locomotor time 20.80.81.7-0.71.10.11.3-0.50.91.11.01.00.50.90.9-1.1-0.8-0.61.1-0.6-0.90.90.9-1.0
Rest time, locomotor task time 20.70.82.81.1-1.0-0.8-0.80.9-0.9-0.9-0.8-0.7-0.6-0.6-0.91.71.00.5-1.00.80.8-0.8-0.70.7
Distance moved, locomotor task time 20.40.41.3-0.00.1-0.30.3-0.30.60.50.80.80.40.70.7-0.9-0.5-1.11.0-0.8-0.50.60.6-0.6
Vertical activity count, locomotor time 20.10.10.30.3-0.4-0.6-0.40.3-0.3-0.3-0.2-0.2-0.4-0.3-0.1-0.2-0.00.10.20.1-0.20.20.2-0.2
Light reinforcement 11.52.84.6-2.01.72.12.1-1.91.91.82.12.11.92.01.6-1.8-1.4-1.31.1-1.4-0.80.70.6-0.6
Light reinforcement 20.81.14.3-0.50.30.90.4-1.11.31.40.90.81.60.71.1-1.5-0.6-2.11.0-1.5-0.20.30.3-0.3
Bone: marrow area1.43.06.92.6-2.0-1.0-1.21.2-1.1-1.3-1.1-1.1-0.4-1.0-2.02.62.4-0.2-1.50.62.5-2.4-2.32.3
Bone: maximum diameter0.10.20.40.10.20.50.5-0.40.30.10.40.40.60.4-0.10.40.3-0.40.3-0.30.6-0.6-0.60.6
Bone: maximum force0.30.61.40.60.30.40.7-0.40.80.70.70.70.80.7-0.30.70.7-0.80.1-0.61.2-1.1-1.11.2
Bone: maximum moment0.30.51.40.80.10.20.5-0.20.60.40.40.40.60.5-0.50.90.8-0.6-0.0-0.41.2-1.1-1.11.1
Mean time between licks in bursts3.24.57.92.1-1.8-0.5-1.31.6-2.4-2.4-1.6-1.5-1.6-1.3-2.82.52.61.9-2.72.02.5-2.6-2.62.6
Mean num. licks in bursts0.30.41.2-0.50.1-0.6-0.10.3-0.2-0.20.20.3-0.40.10.60.5-0.70.50.20.3-1.11.11.1-1.1
Cd content in liver0.30.30.9-0.40.2-0.20.5-0.20.40.50.40.40.30.00.80.1-0.7-0.40.3-0.3-0.90.80.9-0.9
Co content in liver0.91.02.60.5-0.8-1.6-1.01.3-1.1-1.2-1.4-1.4-1.2-1.4-0.00.2-0.00.70.11.0-1.00.91.0-1.0
Cu content in liver0.50.62.0-0.50.5-0.70.30.30.10.0-0.1-0.1-0.4-0.10.8-0.7-0.90.11.00.1-1.41.41.4-1.4
Fe content in liver0.20.21.90.7-0.4-0.7-0.40.30.20.1-0.1-0.20.2-0.20.20.10.2-1.40.4-0.5-0.10.10.3-0.3
K content in liver3.83.86.4-2.02.21.82.0-2.42.52.52.32.32.12.01.9-2.0-1.9-1.61.9-2.4-0.91.00.9-0.8
Mg content in liver3.13.15.7-2.42.31.21.6-1.81.81.81.71.70.91.41.8-2.4-2.3-0.11.9-1.6-1.71.81.6-1.6
Mn content in liver3.33.77.1-2.52.72.32.1-2.52.01.92.52.51.62.41.5-2.5-2.0-0.21.3-1.9-0.80.90.6-0.5
Na content in liver2.12.24.5-0.61.31.71.9-1.91.91.82.02.02.11.80.8-0.1-0.5-1.61.0-2.10.8-0.6-0.70.8
Rb content in liver0.40.41.2-1.10.80.70.5-0.50.50.5-0.1-0.20.3-0.30.8-0.9-0.9-0.20.6-0.1-1.00.90.9-0.9
Se content in liver5.36.510.8-3.33.12.42.5-2.92.72.72.62.62.42.52.9-3.1-2.9-1.42.4-2.5-2.12.11.9-1.8
Sr content in liver0.10.10.4-0.40.1-0.1-0.20.2-0.2-0.2-0.1-0.1-0.4-0.10.1-0.2-0.30.60.20.5-0.60.50.5-0.5
Zn content in liver1.01.12.4-1.60.91.11.0-1.00.90.90.60.61.20.61.4-0.5-1.2-0.81.2-0.6-1.21.11.1-1.1
Bone: minimum diameter0.30.51.41.0-0.6-0.3-0.40.2-0.2-0.3-0.4-0.5-0.1-0.3-0.81.10.90.1-0.3-0.01.2-1.1-1.11.1
Time in familiar zone, hab. session 11.21.14.2-0.00.61.10.8-1.31.41.31.21.21.71.00.5-0.6-0.0-2.00.5-1.60.7-0.6-0.60.7
Time in novel zone, hab. session 10.70.76.1-0.90.2-0.2-0.20.5-1.0-0.9-0.6-0.6-1.3-0.3-0.30.1-0.42.5-0.31.3-0.80.70.5-0.5
Total zone transitions, hab. session 10.91.34.01.2-1.5-2.0-1.81.6-1.1-1.1-1.5-1.5-1.3-1.7-0.40.30.50.1-0.20.9-0.50.50.7-0.7
Total locomotion distance, hab. session 10.30.41.5-0.40.1-0.6-0.30.10.20.20.10.0-0.2-0.30.7-0.9-0.8-0.30.7-0.1-1.21.21.2-1.2
Locomotion velocity, hab. session 10.30.41.4-0.0-0.1-0.8-0.40.20.30.20.10.0-0.1-0.30.7-0.7-0.6-0.70.7-0.3-1.01.01.2-1.2
Time in familiar zone, hab. session 22.42.54.6-1.31.81.11.5-1.81.71.72.02.01.61.81.6-2.0-1.4-1.81.6-2.1-0.70.90.8-0.7
Time in novel zone, hab. session 20.60.61.90.2-0.6-0.0-0.40.6-0.7-0.7-0.8-0.8-0.7-0.8-0.81.30.61.4-0.91.30.4-0.5-0.50.5
Total zone transitions, hab. session 21.01.32.41.4-1.5-1.2-1.61.4-1.2-1.2-1.3-1.3-1.1-1.4-1.11.31.20.4-0.91.10.6-0.7-0.50.5
Total locomotion distance, hab. session 20.40.51.10.9-1.1-0.5-0.90.7-0.6-0.7-0.6-0.5-0.4-0.8-0.80.90.90.1-0.90.60.7-0.7-0.70.7
Locomotion velocity, hab. session 20.40.61.31.1-1.2-0.7-1.00.8-0.6-0.8-0.6-0.6-0.5-0.8-0.80.90.90.1-0.90.60.7-0.7-0.60.6
Novel to familiar place preference ratio0.30.31.20.00.1-1.0-0.00.30.10.10.10.0-0.40.20.5-0.4-0.6-0.20.8-0.2-1.01.01.1-1.1
Novelty place preference0.40.41.5-0.10.1-1.1-0.10.4-0.0-0.00.0-0.0-0.60.10.5-0.4-0.70.10.90.0-1.21.21.2-1.2
Time in novel zone, NPP test0.50.51.6-0.40.5-0.70.20.00.30.30.30.3-0.20.40.7-0.6-0.9-0.11.0-0.3-1.21.21.2-1.2
Total zone transitions, NPP test1.11.63.31.8-1.7-0.8-1.51.2-1.0-0.9-1.3-1.3-0.4-1.5-1.21.41.7-0.6-1.10.91.3-1.4-1.21.2
Total locomotion distance, NPP test0.40.61.11.0-1.1-0.1-0.90.5-0.4-0.4-0.6-0.60.0-0.9-0.70.91.1-0.5-0.80.40.9-1.0-0.90.9
Locomotion velocity, NPP test0.81.12.51.4-1.6-0.8-1.51.1-0.9-0.9-1.1-1.1-0.5-1.4-1.01.21.3-0.2-0.90.90.9-0.9-0.80.7
Intraocular pressure3.75.210.12.3-3.0-2.9-3.23.1-2.8-2.8-3.1-3.1-2.4-3.0-1.51.61.70.9-1.22.5-0.0-0.10.1-0.2
Delta distance traveled before/after self-admin0.40.41.30.6-0.2-0.7-0.70.5-0.8-0.8-0.7-0.7-1.0-0.8-0.70.20.31.1-0.80.20.4-0.3-0.40.4
Delta ambulatory time before/after self-admin0.30.40.90.7-0.1-0.3-0.50.1-0.6-0.6-0.5-0.6-0.5-0.5-0.80.30.50.6-1.0-0.10.9-0.8-0.80.9
Parametrial fat weight1.12.25.1-1.41.61.82.1-1.71.71.71.51.52.31.91.5-0.8-0.9-1.91.2-1.6-0.30.30.3-0.3
Pavlov. Cond. lever latency1.11.46.40.7-0.8-1.3-1.51.0-1.2-1.2-1.2-1.2-2.0-1.2-1.20.30.32.5-1.41.00.3-0.2-0.30.4
Pavlov. Cond. magazine entry latency4.96.310.9-2.93.03.13.3-3.02.82.62.92.93.22.92.6-1.9-2.1-2.42.0-2.5-1.11.00.9-0.9
Pavlov. Cond. change in total contacts4.64.98.0-2.82.31.62.4-1.82.12.11.91.91.91.82.8-2.1-2.5-1.62.8-1.4-2.62.42.4-2.4
Pavlov. Cond. index score2.73.47.8-1.91.92.42.5-2.12.01.92.02.12.82.01.9-0.9-1.2-2.41.7-1.6-0.70.60.5-0.6
Pavlov. Cond. latency score2.02.66.8-1.51.52.12.3-1.81.81.71.81.82.61.71.7-0.6-0.9-2.41.5-1.5-0.40.30.4-0.4
Pavlov. Cond. lever contacts0.50.64.2-0.30.31.01.1-0.60.70.60.70.71.60.70.80.20.1-2.00.8-0.50.0-0.2-0.0-0.0
Pavlov. Cond. magazine entry number5.06.310.03.1-2.9-3.1-3.22.9-2.7-2.5-2.8-2.9-3.0-2.8-2.72.12.32.2-2.22.21.4-1.4-1.21.2
Pavlov. Cond. intertrial magazine entries0.70.92.10.7-0.8-1.2-1.11.1-1.2-1.0-1.2-1.2-1.5-1.3-0.80.50.41.3-0.60.90.00.00.0-0.0
Pavlov. Cond. lever-magazine prob. diff.2.83.57.4-2.12.02.52.6-2.12.01.92.02.12.72.12.0-1.0-1.3-2.21.7-1.5-0.80.70.6-0.6
Pavlov. Cond. response bias4.15.07.9-2.62.42.42.8-2.32.42.32.42.42.72.42.5-1.8-2.0-2.42.3-1.8-1.51.51.4-1.4
Pavlov. Cond. lever latency0.20.31.30.5-0.4-1.1-0.30.7-0.4-0.3-0.7-0.7-0.5-0.30.00.40.10.10.50.4-0.40.40.5-0.5
Pavlov. Cond. magazine entry latency0.10.10.40.3-0.5-0.1-0.50.2-0.4-0.4-0.3-0.2-0.0-0.4-0.20.60.30.0-0.40.20.3-0.3-0.20.2
Pavlov. Cond. change in total contacts0.10.21.1-0.70.41.00.1-0.5-0.0-0.00.30.30.0-0.0-0.3-0.0-0.11.0-0.50.30.3-0.4-0.50.5
Pavlov. Cond. index score0.10.20.7-0.2-0.00.8-0.1-0.4-0.0-0.10.30.30.3-0.1-0.30.00.20.1-0.7-0.10.7-0.6-0.70.7
Pavlov. Cond. latency score0.20.20.70.0-0.20.7-0.3-0.3-0.2-0.30.10.10.2-0.2-0.50.20.40.2-0.90.00.8-0.7-0.80.8
Pavlov. Cond. lever contacts0.40.52.1-0.60.61.50.6-1.00.70.60.90.91.00.50.1-0.6-0.1-0.6-0.2-0.60.6-0.6-0.60.7
Pavlov. Cond. magazine entry number0.10.10.20.2-0.2-0.50.00.5-0.0-0.0-0.4-0.4-0.3-0.1-0.0-0.00.1-0.00.40.3-0.30.20.3-0.3
Pavlov. Cond. intertrial magazine entries1.21.54.11.0-1.3-2.0-1.61.9-1.0-1.0-1.6-1.7-1.7-1.4-0.60.60.50.90.11.6-0.80.70.8-0.9
Pavlov. Cond. lever-magazine prob. diff.0.10.20.5-0.1-0.10.7-0.3-0.3-0.1-0.10.20.20.2-0.2-0.30.10.20.1-0.7-0.10.6-0.6-0.70.7
Pavlov. Cond. response bias0.50.72.4-0.90.91.60.7-1.30.90.81.11.11.20.70.5-0.6-0.4-0.80.0-0.90.2-0.2-0.30.3
Time in closed arm before self-admin0.40.41.9-1.21.01.00.4-0.90.60.40.60.50.10.60.3-1.4-0.80.70.2-0.4-0.40.40.2-0.2
Time in closed arm after self-admin0.30.31.5-0.30.6-0.4-0.20.1-0.1-0.3-0.1-0.2-1.1-0.2-0.2-1.1-0.51.20.10.0-0.40.50.3-0.3
Time in open arm before self-admin0.30.31.21.1-0.8-1.0-0.40.7-0.4-0.4-0.4-0.3-0.2-0.3-0.30.60.7-0.6-0.10.20.3-0.3-0.20.2
Time in open arm after self-admin0.50.51.70.8-0.9-0.8-0.60.9-0.8-0.7-0.8-0.8-0.6-0.7-0.61.30.70.6-0.60.80.3-0.4-0.30.3
Bone: periosteal estimation0.40.72.41.1-0.60.0-0.20.1-0.0-0.3-0.3-0.30.3-0.2-0.91.41.2-0.4-0.4-0.11.6-1.5-1.51.5
Bone: periosteal perimeter0.81.43.71.5-1.1-0.1-0.80.5-0.7-0.9-0.6-0.6-0.2-0.5-1.51.31.60.2-1.00.41.9-1.9-1.91.9
Bone: post-yield work1.01.32.91.7-1.4-1.3-1.11.4-0.8-0.9-1.2-1.2-1.1-1.4-1.31.31.40.3-0.71.10.9-0.9-0.80.8
Progressive ratio test 1 active lever presses0.60.61.0-0.80.40.20.9-0.60.90.90.91.00.61.01.0-0.3-0.9-0.51.0-0.6-0.90.90.9-0.9
Progressive ratio test 1 breakpoint0.60.71.2-0.80.50.30.9-0.71.00.91.01.00.71.11.0-0.4-0.9-0.40.9-0.7-0.80.80.8-0.8
Progressive ratio test 1 inactive lever presses1.92.13.0-1.61.40.71.7-1.21.71.71.61.71.21.71.7-0.8-1.7-0.81.7-1.1-1.51.41.4-1.4
Progressive ratio test 2 active lever presses0.20.21.0-1.00.40.90.3-0.60.50.50.50.50.30.60.3-0.1-0.60.60.10.0-0.30.20.1-0.1
Progressive ratio test 2 breakpoint0.20.20.8-0.90.30.80.3-0.60.50.50.40.50.30.60.3-0.0-0.50.7-0.0-0.0-0.20.10.0-0.0
Progressive ratio test 2 inactive lever presses0.10.20.6-0.80.20.60.1-0.50.40.40.40.50.30.60.3-0.2-0.50.30.1-0.1-0.30.20.2-0.1
Incentive Sensitization - Responses0.80.82.1-0.2-0.60.9-1.00.2-0.8-0.7-0.8-0.8-0.3-0.7-0.90.90.71.4-1.31.20.9-1.0-1.11.1
Incentive Sensitization - Breakpoint0.70.71.9-0.3-0.51.0-0.90.0-0.7-0.6-0.7-0.7-0.2-0.6-0.90.80.71.4-1.41.00.9-1.0-1.21.1
Sum of active levers in priming session hrs 5-62.02.04.0-1.01.51.11.8-1.71.71.61.81.71.71.41.4-1.5-1.2-1.71.1-2.0-0.50.60.5-0.5
Progressive ratio0.30.30.9-0.20.30.80.6-0.60.60.60.80.80.90.80.2-0.10.0-0.90.1-0.60.4-0.3-0.30.3
Food seeking constrained by brief footshock0.60.71.9-0.40.80.91.0-1.00.91.01.11.11.31.20.7-0.7-0.4-1.40.5-1.10.1-0.0-0.00.0
Seeking ratio, punishment vs. effort0.00.00.2-0.00.1-0.2-0.10.1-0.2-0.2-0.2-0.3-0.3-0.2-0.1-0.2-0.10.5-0.10.1-0.10.10.1-0.1
Retroperitoneal fat weight0.00.10.30.40.1-0.20.2-0.10.40.30.30.30.40.40.0-0.10.2-0.50.1-0.40.3-0.3-0.20.2
Reaction time number correct0.60.81.81.3-1.0-0.8-0.51.0-0.7-0.8-0.6-0.5-0.7-0.5-1.11.41.30.3-0.60.91.0-1.0-0.90.9
Reaction time mean minus median1.52.03.21.1-1.6-0.8-1.41.4-1.8-1.7-1.5-1.5-1.3-1.5-1.61.61.41.8-1.41.71.0-1.0-1.01.0
Reaction time mean minus median AUC0.81.01.90.6-1.1-0.4-0.81.0-1.3-1.3-1.1-1.0-0.9-1.0-1.11.20.91.4-1.01.30.6-0.7-0.70.7
Reaction time num false alarms0.50.72.1-0.10.51.40.7-0.90.40.50.70.71.00.8-0.3-0.10.5-0.7-0.2-0.61.3-1.2-1.41.4
Reaction time num false alarms AUC0.70.93.50.20.31.50.5-0.70.00.20.50.50.80.6-0.80.21.0-0.3-0.6-0.21.7-1.7-1.81.9
Reaction time trials correct on left0.60.81.81.3-1.0-0.8-0.51.0-0.7-0.8-0.6-0.5-0.7-0.5-1.11.41.30.3-0.60.91.0-1.0-0.90.9
Reaction time trials on left0.60.81.91.3-1.0-0.7-0.51.0-0.7-0.8-0.6-0.5-0.7-0.5-1.11.41.30.3-0.70.91.0-1.0-1.00.9
Reaction time mean0.20.31.1-1.10.60.30.3-0.50.20.30.20.2-0.10.20.6-0.8-1.00.70.4-0.2-0.80.90.8-0.7
Reaction time mean AUC0.30.51.3-1.10.70.30.5-0.50.30.40.30.30.00.30.7-0.9-1.10.60.5-0.3-1.01.00.9-0.9
Median of all reaction times1.01.43.4-1.81.51.01.0-1.21.01.01.00.90.60.91.3-1.6-1.70.10.9-0.9-1.31.31.2-1.2
Reaction time omissions0.40.61.4-1.00.91.20.9-1.00.80.70.90.90.90.90.7-0.7-0.6-0.50.4-0.7-0.20.20.1-0.1
Reaction time false alarm rate0.50.72.9-0.50.81.70.8-1.10.50.60.70.71.10.8-0.1-0.50.2-0.4-0.2-0.71.0-1.0-1.21.2
Reaction time premature initiation rate3.64.87.0-1.92.11.02.4-2.12.52.22.42.42.02.42.6-2.3-2.4-2.32.1-2.6-1.81.91.9-1.9
Reaction time premature initiations1.31.92.9-0.81.20.31.7-1.11.71.41.61.61.21.61.6-1.2-1.3-1.71.4-1.7-1.01.11.2-1.2
Std. dev. reaction times0.40.62.20.2-0.7-0.0-0.50.5-1.0-1.0-0.8-0.8-0.7-0.7-0.90.80.61.5-1.00.90.6-0.6-0.70.7
Reaction time trials completed0.60.81.91.3-1.0-0.7-0.51.0-0.7-0.8-0.6-0.5-0.7-0.5-1.11.41.30.3-0.70.91.0-1.0-1.00.9
Reaction time trials AUC0.60.91.91.3-1.0-0.7-0.61.0-0.8-0.9-0.6-0.6-0.8-0.6-1.31.41.30.6-0.81.01.0-1.1-1.01.0
Run reversals in cocaine runway, females1.71.66.00.30.0-2.4-0.31.2-0.0-0.1-0.1-0.1-1.3-0.20.8-0.6-0.9-0.11.80.4-2.12.12.2-2.3
Run reversals in cocaine runway, males0.60.61.5-0.70.5-0.10.3-0.20.40.40.60.60.40.61.0-0.3-0.9-0.71.0-0.3-1.21.21.2-1.2
Latency to leave start box in cocaine runway0.40.51.20.8-0.1-0.8-0.60.7-0.9-0.9-0.7-0.7-1.1-0.7-0.8-0.30.50.9-0.70.50.5-0.4-0.40.5
Latency to leave start box in cocaine runway, F0.10.21.10.7-0.0-1.00.00.5-0.4-0.4-0.4-0.4-0.6-0.4-0.1-0.40.1-0.00.0-0.1-0.10.20.2-0.2
Latency to leave start box in cocaine runway, M0.20.21.0-0.50.70.4-0.3-0.2-0.1-0.10.10.0-0.50.0-0.2-0.9-0.31.0-0.20.2-0.00.1-0.10.1
Std. dev. time between licks in bursts0.70.82.90.7-0.20.70.10.0-0.7-0.5-0.2-0.2-0.1-0.2-1.20.51.20.4-1.30.31.6-1.6-1.71.7
Total sessions with >9 infusions1.31.42.2-1.31.20.41.3-0.91.31.31.31.30.61.31.3-1.1-1.5-0.41.4-0.9-1.31.31.3-1.2
Short access day 1 total inactive lever presses1.31.42.4-1.50.80.61.2-0.91.41.41.31.31.11.31.5-0.1-1.4-0.61.4-0.6-1.41.31.3-1.4
Short access day 10 total inactive lever presses0.30.41.0-0.10.4-0.30.7-0.10.60.60.50.50.40.50.8-0.1-0.5-1.01.0-0.5-0.70.70.8-0.8
Short access day 1 total infusions3.43.66.4-1.61.40.11.9-1.22.12.02.12.11.32.12.3-1.2-2.2-1.52.5-1.5-2.22.22.3-2.3
Short access day 10 total infusions0.40.40.9-0.60.20.50.8-0.70.80.70.80.81.00.80.80.1-0.6-1.00.6-0.7-0.50.40.5-0.5
Short access total infusions2.52.85.1-1.41.20.11.8-1.01.81.71.81.81.11.82.0-1.1-1.9-1.42.2-1.4-2.02.02.0-2.0
Short access day 1 locomotion2.32.53.7-1.91.51.41.6-1.61.81.71.81.81.71.81.8-1.7-1.7-1.21.5-1.3-1.31.21.2-1.2
Short access day 10 total locomotion0.91.03.2-0.4-0.51.6-0.6-0.6-0.3-0.4-0.4-0.40.3-0.3-0.90.60.61.5-1.80.31.4-1.4-1.61.6
Short access total locomotion0.10.11.5-0.5-0.10.4-0.1-0.10.0-0.0-0.00.0-0.20.0-0.20.0-0.11.2-0.50.40.1-0.1-0.20.2
One hour access (0.3 mA shock)0.00.00.2-0.3-0.20.00.1-0.10.10.10.20.2-0.10.20.10.2-0.30.4-0.00.0-0.20.20.2-0.2
Compulsive drug intake1.81.95.50.8-1.4-1.7-1.12.0-1.4-1.4-1.3-1.3-2.2-1.3-1.21.20.72.2-0.62.4-0.30.20.2-0.3
One hour access (shock baseline)0.91.12.1-0.90.80.91.0-1.31.21.21.21.21.51.21.1-0.7-0.9-1.40.8-1.5-0.40.40.4-0.4
Social response proportion0.20.20.70.5-0.1-0.8-0.50.4-0.0-0.0-0.3-0.3-0.2-0.50.2-0.1-0.0-0.70.6-0.1-0.40.40.5-0.6
Social responses0.20.22.20.10.00.2-0.2-0.30.50.50.30.30.80.00.4-0.40.0-1.50.4-0.70.1-0.00.0-0.0
Social time0.71.03.81.3-1.2-0.1-0.70.6-0.6-0.6-0.5-0.50.3-0.8-0.81.91.5-0.7-0.60.51.3-1.4-1.21.2
Soleus weight0.41.13.41.0-0.40.70.3-0.40.20.20.20.21.00.4-0.71.21.2-1.2-1.0-0.61.8-1.8-1.71.8
Bone: stiffness0.50.72.00.00.60.31.0-0.81.41.31.21.21.10.90.60.0-0.2-1.40.8-1.20.2-0.1-0.00.0
Tibialis anterior weight0.41.44.02.0-1.9-1.9-1.51.3-0.8-0.8-1.4-1.4-0.6-1.3-0.71.61.1-0.7-0.40.30.6-0.5-0.30.3
Time to tail flick, vehicle, before self-admin1.81.93.61.0-1.5-0.5-1.71.5-1.7-1.7-1.6-1.6-1.2-1.6-1.41.21.41.2-1.51.90.9-1.0-1.00.9
Time to tail flick, vehicle, after self-admin0.40.42.40.7-1.3-0.4-0.50.8-0.4-0.6-0.6-0.50.0-0.5-0.31.60.9-0.4-0.40.80.3-0.4-0.30.2
Time to tail flick, test, before self-admin0.80.81.61.1-1.1-0.9-1.31.0-0.9-1.2-0.8-0.8-0.9-1.0-1.00.80.90.6-0.90.80.6-0.6-0.60.6
Time to tail flick, test, after self-admin0.80.81.70.8-1.3-0.0-1.30.8-1.1-1.2-0.8-0.8-0.4-0.9-0.90.91.10.3-1.11.00.9-0.9-0.90.9
Delta time to tail flick, vehicle, before/after SA0.50.51.70.1-0.20.90.7-0.60.60.50.50.51.30.50.21.00.4-1.3-0.2-0.70.8-0.8-0.70.7
Delta time to tail flick, test, before/after SA0.10.10.3-0.5-0.10.50.1-0.1-0.0-0.00.20.20.50.10.4-0.0-0.1-0.50.30.3-0.30.20.2-0.3
Tibia length0.51.45.32.3-1.6-1.7-1.01.3-0.7-0.9-1.1-1.0-0.4-1.2-0.91.71.5-1.1-0.60.21.1-1.0-0.80.7
Ambulatory time before self-admin0.20.20.70.4-0.6-0.8-0.10.7-0.2-0.3-0.3-0.2-0.2-0.20.20.70.2-0.40.30.5-0.50.40.6-0.6
Ambulatory time after self-admin0.60.72.11.3-0.9-1.2-0.60.9-0.8-0.9-0.8-0.8-0.6-0.8-0.61.40.8-0.1-0.70.30.6-0.5-0.40.4
Bone: tissue strength2.52.43.91.6-1.4-0.9-1.11.6-1.7-1.6-1.4-1.4-1.6-1.4-2.01.71.81.6-1.71.91.4-1.5-1.51.4
Total heroin consumption1.21.44.6-0.70.72.11.3-1.51.21.21.31.22.11.30.5-0.60.0-1.8-0.0-1.20.9-0.9-0.90.9
Bone: trabecular number3.96.111.0-2.42.83.03.2-3.13.33.32.92.93.22.92.2-1.6-1.7-2.32.3-2.6-0.40.50.3-0.2
Bone: trabecular spacing1.21.63.81.8-1.9-1.3-1.91.3-1.3-1.3-1.5-1.5-0.6-1.5-0.91.51.3-0.5-1.10.70.8-0.8-0.50.5
Bone: trabecular thickness0.30.31.3-0.10.20.80.2-0.40.10.2-0.1-0.10.1-0.0-0.60.30.40.8-0.40.11.0-1.0-1.11.1
Bone: trabecular tissue density0.50.71.8-0.4-0.0-1.1-0.50.9-0.7-0.6-0.4-0.4-1.2-0.20.2-0.1-0.61.30.31.0-1.41.31.3-1.3
Water consumed over 24 hours0.40.51.00.7-0.7-0.0-0.80.4-0.5-0.7-0.7-0.7-0.4-0.7-0.90.60.90.6-0.90.61.0-1.0-1.01.0
Number of responses in last shaping day0.90.92.2-1.51.30.90.9-1.21.01.11.11.20.21.20.6-0.9-1.21.10.3-0.7-0.50.60.4-0.3