Hub : Genes

Kpna2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Kpna2 0.05 0.02 1.2e-04 0.01 0.03 0.01 0.01 1.0e-02 7.1e-04 7.6e-03 7.2e-03
2 Liver gene expression Kpna2 0.14 0.06 2.2e-10 0.06 0.07 0.06 0.06 1.2e-07 2.5e-08 9.1e-07 1.1e-07
3 Liver mRNA stability Kpna2 0.04 0.02 3.4e-04 0.01 0.02 0.02 0.01 9.9e-03 4.2e-03 4.1e-03 3.9e-02
4 BLA gene expression Kpna2 0.09 0.05 2.4e-04 0.07 0.05 0.06 0.06 2.1e-04 1.8e-03 2.4e-04 3.0e-04
5 IC gene expression Kpna2 0.11 0.06 1.4e-04 0.09 0.1 0.09 0.08 1.4e-04 4.0e-05 1.5e-04 3.1e-04
6 Eye gene expression Kpna2 0.37 0.16 5.2e-03 0.2 0.08 0.04 0.15 5.2e-04 2.7e-02 7.1e-02 2.6e-03
7 Brain gene expression Kpna2 0.23 0.11 5.5e-14 0.12 0.12 0.1 0.13 4.1e-11 2.5e-11 8.1e-10 2.1e-12
8 Brain mRNA stability Kpna2 0.03 0.02 7.0e-03 0.02 0.02 0.01 0.01 8.1e-03 7.3e-03 4.7e-02 1.5e-02
9 NAcc gene expression Kpna2 0.16 0.06 0.0e+00 0.19 0.19 0.21 0.21 4.2e-28 2.2e-27 1.2e-30 2.0e-30
10 IC intron excision ratio chr10_92444072_92445739 0.09 0.06 4.4e-03 0.01 0.03 0.04 0.02 1.4e-01 2.9e-02 6.7e-03 4.4e-02
11 PL gene expression Kpna2 0.13 0.05 4.1e-13 0.07 0.12 0.12 0.12 3.1e-08 3.7e-13 1.8e-13 1.0e-12
12 IL gene expression Kpna2 0.33 0.12 3.8e-06 0.1 0.15 0.08 0.1 1.8e-03 1.7e-04 4.9e-03 2.3e-03
13 pVTA gene expression Kpna2 0.1 0.05 1.2e-06 0.09 0.08 0.1 0.09 2.2e-07 3.2e-07 3.4e-08 2.3e-07
14 Liver isoform ratio NM_053483.2 0.03 0.02 8.1e-03 -0 0.01 0.01 0 4.4e-01 1.9e-02 1.2e-02 1.7e-01
15 Brain isoform ratio NM_053483.2 0.06 0.04 1.7e-03 0 0.02 -0 -0 2.0e-01 8.3e-03 4.3e-01 4.6e-01
16 Brain isoform ratio NM_001270802.1 0.07 0.04 1.7e-03 -0 0.02 0 -0 9.3e-01 1.1e-02 2.8e-01 5.1e-01
17 Adipose gene expression Kpna2 0.33 0.1 0.0e+00 0.37 0.35 0.37 0.36 3.3e-43 2.3e-40 2.1e-43 4.0e-42
18 LHb gene expression Kpna2 0.17 0.09 3.4e-03 0.06 0.11 0.1 0.08 1.7e-02 1.8e-03 2.4e-03 5.3e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.30.61.71.20.41.2-0.7-1.00.4-1.31.0-0.8-0.3-0.7-0.8-0.8-0.2-0.00.1-0.3-0.9
Area under the delay curve0.50.62.30.40.30.70.2-0.5-0.1-0.4-0.3-0.61.5-0.8-0.6-1.50.61.1-1.10.7-0.8
BMI with tail1.44.818.32.14.32.1-2.0-3.21.0-3.11.0-2.10.1-1.9-3.1-2.52.00.8-0.9-0.8-1.6
BMI without tail2.99.030.63.25.52.8-2.9-4.42.0-4.21.7-3.4-0.5-3.2-4.0-2.92.31.0-1.1-1.2-2.3
Body weight3.013.029.34.15.44.3-3.9-5.13.2-4.83.1-4.2-0.9-4.1-4.2-4.21.10.6-0.6-1.8-3.1
Weight adjusted by age0.30.51.7-0.4-0.6-0.51.10.7-0.70.8-1.00.60.40.40.51.1-0.20.4-0.41.30.3
Bone surface2.64.710.63.21.13.1-2.7-2.32.1-2.63.3-2.2-2.2-2.0-1.2-1.6-2.0-1.51.6-1.2-1.4
Bone volume2.13.88.32.91.42.8-2.3-2.31.8-2.62.7-2.1-1.5-1.9-1.5-1.7-1.2-0.80.9-1.0-1.6
Breakpoint value in progressive ratio session0.81.02.00.1-0.2-0.81.30.70.51.0-0.70.8-1.01.21.21.2-1.3-1.01.01.01.4
Number of licking bursts0.20.31.50.3-0.6-0.40.00.40.20.50.00.3-0.30.40.70.4-1.2-0.70.71.10.6
Context. condit. distance diff. score0.10.10.20.30.2-0.30.00.10.10.2-0.10.1-0.20.40.10.4-0.1-0.50.5-0.30.4
Locomotion velocity, session 10.40.41.11.10.80.2-0.5-0.90.6-0.90.7-0.8-0.3-0.8-0.6-0.8-0.1-0.20.2-0.3-0.4
Locomotion distance, session 10.40.51.21.11.10.2-0.5-0.9-0.3-1.10.2-0.80.4-0.9-0.7-1.00.50.1-0.10.1-0.4
Locomotion velocity, session 21.21.56.01.00.40.1-0.50.01.10.20.70.1-2.50.51.01.6-1.8-2.02.0-0.31.2
Locomotion distance, session 20.30.51.41.00.3-0.50.30.0-0.30.2-0.20.4-0.50.40.70.5-1.0-1.21.20.91.1
Locomotion velocity, session 30.80.92.90.60.2-1.01.60.5-0.70.6-1.31.00.41.00.80.7-0.7-0.60.71.71.3
Locomotion distance, session 30.40.41.80.9-0.10.00.60.2-0.20.2-0.00.4-0.70.40.70.6-1.3-1.01.00.80.7
Stereotopy head waving bouts, day 30.60.73.3-0.8-0.4-0.91.10.5-0.70.4-1.10.51.80.5-0.0-0.60.81.0-1.00.6-0.0
Stereotopy head waving duration, day 30.60.73.9-0.5-0.4-0.91.20.5-0.60.6-1.30.62.00.50.2-0.70.50.9-0.91.10.2
Locomotion velocity, session 70.20.20.6-0.6-0.4-0.80.30.5-0.70.3-0.20.7-0.10.70.20.60.3-0.20.2-0.10.4
Locomotion distance, session 70.00.00.20.00.10.1-0.0-0.1-0.2-0.2-0.0-0.2-0.4-0.2-0.10.40.20.0-0.00.10.0
Stereotopy head waving bouts, day 71.41.63.2-0.3-0.9-1.51.71.4-0.71.5-1.51.50.81.71.60.7-0.9-0.70.71.81.7
Stereotopy head waving duration, day 73.03.66.1-1.0-1.8-2.12.32.3-1.12.5-1.92.40.82.42.41.4-1.3-1.01.02.22.3
Locomotion velocity, session 80.40.52.20.80.10.5-0.5-0.40.8-0.41.2-0.3-1.5-0.1-0.00.1-1.0-1.00.9-0.9-0.1
Locomotion distance, session 80.20.31.31.00.5-0.1-0.3-0.20.3-0.10.30.0-0.90.30.30.4-0.8-1.11.1-0.20.6
Degree of sensitization distance0.60.71.4-0.20.30.6-0.8-0.80.4-0.80.6-1.10.3-1.2-1.0-1.01.00.9-0.9-0.7-1.0
Degree of sensitization stereotypy2.32.55.7-0.2-0.7-1.51.71.6-0.71.8-1.61.9-0.12.02.11.8-1.3-1.51.51.92.4
Conditioned locomotion0.20.20.60.20.60.5-0.4-0.70.5-0.50.4-0.7-0.3-0.7-0.6-0.50.20.4-0.4-0.3-0.6
Cocaine response after cond. corrected0.50.62.8-0.8-1.7-0.60.70.9-1.20.7-0.50.70.80.40.70.1-0.30.3-0.30.90.2
Cocaine response after cond. not corrected1.51.75.8-0.6-2.4-0.90.91.8-1.01.6-0.71.50.31.51.90.9-1.5-1.01.01.21.3
Cocaine response before conditioning1.11.33.60.6-0.4-0.30.41.00.31.0-0.31.1-0.31.61.60.7-1.6-1.91.90.61.7
Saline control response0.71.05.30.92.31.1-0.8-1.22.1-0.50.5-1.0-0.9-0.4-0.6-0.80.1-0.20.2-0.4-0.0
Bone: connectivity density0.81.22.51.60.51.6-1.1-1.30.8-1.51.5-1.3-0.7-1.1-0.9-1.3-0.8-0.40.4-0.5-1.0
Bone: cortical apparent density1.92.69.3-1.5-0.4-2.01.81.0-2.70.8-2.31.63.01.0-0.1-0.31.91.5-1.41.70.4
Bone: cortical area1.11.77.32.72.21.6-1.4-1.70.2-1.91.0-0.7-0.4-0.7-1.1-0.9-0.7-1.21.20.3-0.2
Bone: cortical porosity2.83.08.62.20.91.6-1.8-0.62.3-0.21.8-0.4-2.80.10.90.4-2.9-2.82.8-0.50.9
Bone: cortical porosity2.32.46.42.51.41.8-1.7-1.01.9-0.71.5-0.6-2.2-0.10.4-0.0-2.4-2.42.3-0.10.6
Bone: cortical thickness2.84.616.7-0.60.5-2.32.41.3-4.11.0-3.42.83.22.30.61.01.30.3-0.33.11.9
Bone: cortical thickness1.72.05.7-0.40.2-1.61.01.2-2.41.1-1.92.11.11.90.81.60.3-0.80.71.91.8
Bone: cortical tissue density1.92.68.9-1.6-0.4-2.01.71.1-2.60.9-2.31.53.01.0-0.1-0.22.01.5-1.51.60.4
Condit. Reinf. active minus inactive responses1.51.64.61.81.82.1-2.1-1.11.9-0.51.1-1.0-1.2-0.50.0-0.8-1.0-1.21.1-0.60.1
Condit. Reinf. active-inactive response ratio0.50.52.01.00.50.8-1.1-0.31.40.20.6-0.4-0.90.10.4-0.0-0.9-1.00.9-0.30.4
Condit. Reinf. active responses2.12.67.62.32.22.8-2.6-1.62.1-1.11.6-1.5-1.4-1.0-0.4-1.3-1.1-1.21.1-0.7-0.4
Condit. Reinf. inactive responses1.31.65.61.61.52.4-1.8-1.50.7-1.51.3-1.3-0.5-1.3-0.9-1.6-0.4-0.20.2-0.3-1.0
Incentive salience index mean1.21.53.61.81.51.7-1.9-0.91.9-0.41.2-0.7-1.6-0.20.3-0.3-1.5-1.51.5-0.30.3
Condit. Reinf. lever presses0.50.72.00.60.50.3-0.40.11.00.50.20.3-1.40.70.80.8-1.4-1.31.20.50.9
Condit. Reinf. active minus inactive responses3.34.315.74.01.92.8-2.1-1.92.4-1.32.1-1.4-2.0-0.90.0-1.1-2.9-2.62.60.50.3
Condit. Reinf. active-inactive response ratio1.31.55.12.00.51.6-1.1-0.71.7-0.11.2-0.7-1.7-0.20.5-0.2-2.3-1.61.60.50.3
Condit. Reinf. active responses4.36.017.44.23.03.5-2.9-2.73.0-2.22.7-2.3-2.0-1.8-0.9-2.0-2.1-2.22.2-0.6-0.5
Condit. Reinf. inactive responses2.83.610.32.73.22.7-2.4-2.41.8-2.41.7-2.0-0.9-1.8-1.5-1.8-0.1-0.90.8-1.1-0.8
Condit. Reinf. lever presses1.82.56.82.62.31.8-2.2-1.41.9-0.91.4-0.9-1.8-0.4-0.0-0.3-1.6-2.12.1-0.30.5
Condit. Reinf. lever reinforcers received3.65.014.23.82.73.1-2.8-2.52.8-2.12.5-2.2-1.9-1.7-0.8-1.8-1.8-2.02.0-0.7-0.5
Conditioned reinforcement - actives0.30.52.00.91.40.8-0.3-1.01.0-0.80.1-0.7-0.3-0.6-0.6-0.50.20.2-0.30.2-0.3
Conditioned reinforcement - inactives1.01.43.51.31.71.1-1.1-1.61.1-1.91.2-1.3-1.3-1.1-1.3-0.40.5-0.20.2-1.7-0.9
Conditioned locomotion2.02.65.51.82.42.1-1.6-2.22.1-1.91.5-2.1-1.1-1.8-1.7-1.5-0.10.2-0.2-0.8-1.4
Patch foraging indifference point 0 sec3.46.313.83.33.73.1-3.6-3.42.1-3.02.5-2.8-0.8-2.8-2.5-2.80.1-0.20.2-1.1-1.9
Patch foraging indifference point AUC0.91.32.71.51.51.2-0.8-1.51.5-1.61.3-1.6-1.2-1.2-1.2-0.4-0.2-0.20.2-0.7-0.9
Delay disc. indifference point, 0s delay0.50.51.4-0.8-1.0-0.90.90.6-0.40.6-0.80.21.20.00.2-0.20.61.1-1.00.9-0.3
Delay disc. indifference point, 16s delay0.91.04.30.70.81.3-0.0-0.9-0.1-0.6-0.3-0.71.6-1.0-0.9-2.10.61.3-1.30.9-1.0
Delay disc. indifference point, 2s delay0.80.93.11.1-0.00.8-1.0-0.90.5-1.10.9-1.20.9-1.4-0.8-1.8-0.10.6-0.60.3-1.4
Delay disc. indifference point, 24s delay2.32.66.61.62.12.6-1.2-2.10.7-2.00.8-1.70.7-1.9-2.0-2.20.71.1-1.1-0.1-1.7
Delay disc. indifference point, 4s delay0.70.71.5-0.5-1.0-1.01.21.0-0.61.1-1.10.91.10.70.90.2-0.20.1-0.11.20.6
Delay disc. indifference point, 8s delay0.60.72.6-0.30.0-0.10.7-0.2-0.5-0.2-0.7-0.31.6-0.5-0.6-1.11.01.4-1.40.7-0.8
Indifference point function ln k0.40.71.80.0-0.1-0.50.20.7-1.20.8-1.01.31.11.10.90.1-0.0-0.60.61.21.1
Indifference point function log k0.40.71.80.0-0.1-0.50.20.7-1.20.8-1.01.31.11.10.90.1-0.0-0.60.61.21.1
Patch foraging total patch changes 0 sec3.46.313.13.33.63.0-3.4-3.42.1-3.02.5-2.9-0.9-2.9-2.5-2.90.1-0.20.1-1.1-1.9
Patch foraging total patch changes 12 sec5.06.511.92.82.93.0-3.2-3.33.1-2.93.0-3.5-2.0-3.1-2.4-2.1-0.5-0.0-0.0-1.7-2.3
Patch foraging total patch changes 18 sec1.92.97.22.32.71.8-1.8-2.32.3-2.01.7-2.2-1.6-1.8-1.5-1.1-0.4-0.60.5-1.0-0.9
Patch foraging total patch changes 24 sec2.84.89.93.13.12.8-2.5-3.02.0-2.82.1-2.6-0.9-2.6-2.3-2.1-0.3-0.20.2-0.6-1.7
Patch foraging total patch changes 6 sec2.94.410.32.82.92.6-3.2-2.71.9-2.62.4-2.2-1.4-2.0-1.9-1.6-0.2-0.60.6-1.5-1.5
Patch foraging time to switch 0 sec0.40.83.0-1.7-1.3-1.21.01.2-0.51.4-0.90.80.00.70.81.00.00.6-0.60.10.4
Patch foraging water rate 0 sec1.73.78.12.32.72.8-2.4-2.51.1-2.71.9-2.0-0.8-2.1-2.1-1.70.5-0.20.2-1.4-1.5
Patch foraging water rate 12 sec0.30.73.10.2-0.2-0.40.20.5-1.60.1-0.91.21.80.60.3-0.50.0-0.50.51.30.9
Patch foraging water rate 18 sec0.40.61.81.20.00.5-0.7-0.0-1.1-0.1-0.10.80.80.30.3-0.4-1.0-1.01.01.30.7
Patch foraging water rate 24 sec0.20.31.10.5-0.50.5-0.20.3-0.60.2-0.20.50.40.10.6-0.0-1.0-0.60.61.00.5
Patch foraging water rate 6 sec0.20.31.60.60.50.4-0.1-0.3-0.8-0.5-0.20.11.3-0.2-0.3-1.00.30.0-0.01.00.0
Seeking ratio, delayed vs. immediate footshock0.20.30.9-0.21.00.9-0.0-0.4-0.0-0.2-0.3-0.30.4-0.4-0.7-0.50.90.7-0.7-0.2-0.4
Distance traveled before self-admin1.31.63.6-0.2-1.6-1.11.51.5-0.81.5-1.21.40.91.41.80.4-1.4-0.80.91.91.5
Distance traveled after self-admin1.01.33.90.8-0.9-0.40.30.90.30.9-0.20.9-0.51.21.61.0-2.0-1.81.81.21.5
Extensor digitorum longus weight1.66.424.2-4.2-0.3-1.31.70.5-1.70.5-1.90.03.3-0.5-1.7-1.34.94.6-4.6-1.1-1.9
Bone: elastic displacement1.41.63.7-0.7-0.7-1.41.21.4-1.91.2-1.71.91.31.71.10.90.1-0.30.31.41.4
Bone: elastic work0.10.20.90.51.0-0.0-0.6-0.4-0.8-0.70.10.30.20.2-0.60.00.4-0.30.2-0.1-0.0
Bone: endosteal estimation8.919.642.25.02.86.0-6.2-4.36.1-4.16.5-4.8-5.4-4.0-2.0-2.6-3.3-3.02.9-4.1-2.4
Bone: endosteal perimeter9.720.641.95.73.26.2-5.7-4.96.1-4.76.5-5.2-4.8-4.5-2.6-3.3-3.1-2.42.4-3.6-3.0
Epididymis fat weight0.41.32.90.71.50.8-1.1-1.71.0-1.50.9-1.5-0.5-1.5-1.7-1.00.80.9-0.9-0.1-1.4
Delta time in closed arm before/after self-admin0.30.31.6-0.7-0.9-1.3-0.10.4-0.20.20.2-0.0-0.30.00.10.90.10.2-0.1-0.7-0.3
Delta time in open arm before/after self-admin0.50.51.6-0.40.50.40.8-0.20.30.1-0.8-0.41.1-0.4-0.5-0.91.11.3-1.30.2-0.5
Diff in mean of infusions in LGA sessions1.31.63.5-1.5-0.6-1.91.81.3-1.41.4-1.71.70.71.50.91.30.70.2-0.31.01.2
Delay discount exponential model param0.60.62.5-0.5-0.4-0.90.10.7-0.00.60.10.7-1.30.90.71.6-0.5-1.01.0-0.51.0
Extinction: sum of active levers before priming0.10.20.60.10.4-0.30.4-0.20.20.1-0.3-0.20.8-0.2-0.2-0.70.00.4-0.40.8-0.1
Active lever presses in extinction session 60.70.72.61.11.40.4-1.0-1.01.6-0.70.8-0.9-0.7-0.5-0.4-0.6-0.3-0.50.4-0.5-0.2
Bone: final force0.81.25.12.30.71.0-1.8-1.1-0.1-1.51.3-0.4-0.7-0.3-0.5-0.5-1.1-1.51.50.1-0.1
Bone: final moment0.81.24.92.20.71.0-1.9-1.0-0.2-1.41.3-0.3-0.7-0.2-0.4-0.3-1.1-1.61.60.10.0
Food consumed during 24 hour testing period1.82.55.51.32.31.0-1.3-2.31.7-2.21.4-2.0-0.6-1.8-2.1-1.70.70.7-0.8-0.9-1.6
Glucose1.01.64.0-0.8-1.2-2.02.01.5-1.21.3-1.61.61.01.31.40.9-0.3-0.20.21.41.3
Heart weight0.40.64.00.1-0.0-0.50.80.1-1.20.0-1.10.41.30.0-0.1-0.10.60.7-0.72.00.1
Delay discount hyperbolic model param0.50.62.3-0.5-0.3-0.80.10.6-0.10.6-0.00.7-1.21.00.71.5-0.5-1.01.0-0.41.0
Intermittent access intake day 1-15 change0.10.21.3-1.0-0.7-0.50.00.30.10.60.4-0.0-0.00.1-0.0-0.10.20.2-0.2-1.1-0.2
Intermittent access intake escalation0.10.21.3-0.4-0.10.0-0.4-0.10.60.10.7-0.4-0.2-0.2-0.3-0.40.10.1-0.1-1.1-0.4
Intermittent access intake escalation 20.40.52.7-0.6-0.3-0.1-0.6-0.30.8-0.11.2-0.7-0.7-0.6-0.6-0.20.20.2-0.2-1.7-0.8
Intermitt. access day 1 inactive lever presses0.51.84.01.51.91.8-1.3-1.62.0-1.51.6-1.3-1.6-1.0-0.8-0.8-0.1-0.70.7-1.4-0.6
Intermitt. access day 15 inactive lever presses0.71.44.5-0.01.71.1-1.0-1.31.2-1.41.1-1.1-1.3-0.8-1.4-0.51.40.6-0.6-2.1-1.1
Intermitt. access escalation Index2.63.77.8-1.0-2.3-2.22.12.3-1.72.3-1.82.41.12.42.31.2-1.2-0.90.92.82.1
Intermittent access day 1 total infusions0.71.15.72.41.81.0-1.1-1.21.1-1.20.5-0.6-0.8-0.4-0.2-0.3-1.0-1.11.10.50.3
Intermittent access day 15 total infusions0.81.23.01.51.71.0-1.3-1.51.4-1.31.0-1.2-0.4-1.0-1.0-1.2-0.0-0.10.1-0.6-0.7
Intermittent access terminal intake (last 3 days)1.92.54.41.91.81.6-2.0-2.11.9-2.01.9-1.9-1.2-1.6-1.4-1.4-0.2-0.30.3-1.4-1.3
Intermittent access total infusions2.22.67.52.72.31.9-2.1-2.11.8-2.11.6-1.6-1.2-1.4-1.1-1.2-0.7-0.80.8-0.7-0.8
Intermittent access day 1 locomotion2.53.210.13.03.22.3-2.2-2.32.0-2.21.4-1.5-1.9-1.2-1.1-0.4-0.7-1.21.1-0.5-0.3
Intermittent access day 15 total locomotion2.75.09.73.13.12.8-3.0-2.92.8-2.62.4-2.4-1.8-2.0-1.8-1.6-0.6-0.90.9-1.5-1.2
Intermittent access total locomotion6.57.718.94.24.33.6-3.8-3.63.2-3.32.8-2.8-2.5-2.3-2.1-1.4-0.9-1.41.4-1.4-1.2
Intermittent access standard deviation0.50.92.60.51.21.3-0.9-1.10.9-1.11.1-1.1-0.7-1.0-1.0-1.00.40.0-0.0-1.6-0.9
Left kidney weight0.20.82.11.50.2-0.2-0.20.1-0.9-0.3-0.50.80.70.60.60.1-0.8-1.41.41.41.3
Right kidney weight0.10.62.81.60.1-0.10.0-0.1-0.8-0.5-0.30.70.70.50.3-0.0-1.0-1.11.11.70.8
Cocaine induced anxiety0.50.81.9-0.1-0.6-0.40.11.0-1.20.8-0.71.40.61.31.20.6-0.4-1.01.00.41.3
Post-drug Anxiety0.50.51.9-0.4-0.6-0.60.30.9-1.40.7-0.81.10.60.90.70.80.1-0.40.40.30.8
Baseline Anxiety0.50.51.9-0.80.2-1.00.7-0.2-0.3-0.1-0.5-0.40.4-0.7-0.90.21.11.4-1.40.1-0.7
Tail length1.87.011.73.33.43.1-3.2-3.43.3-3.13.0-3.3-2.4-2.9-2.4-1.8-0.4-0.60.6-1.8-1.9
Length with tail1.56.510.83.12.23.3-3.0-3.13.2-3.03.2-3.2-1.5-3.2-2.1-2.8-1.0-0.30.3-1.7-2.3
Length without tail0.30.92.70.3-0.01.0-0.8-0.90.7-1.11.2-1.10.3-1.4-1.0-1.6-0.10.8-0.8-0.7-1.6
Times rat made contact with spout0.30.30.90.60.30.9-0.3-0.60.8-0.70.8-0.7-0.5-0.3-0.3-0.9-0.7-0.50.4-0.3-0.2
Lifetime Intake2.53.19.13.02.82.1-2.1-2.32.0-2.31.5-1.7-1.3-1.4-1.3-1.2-0.7-0.90.9-0.7-0.7
Liver weight, left2.64.210.33.21.02.3-2.1-1.62.8-1.42.7-1.5-2.8-0.9-0.1-0.2-3.1-2.72.7-0.60.0
Liver weight, right0.40.81.90.3-0.1-1.00.70.6-1.40.2-1.21.20.81.00.60.70.0-0.80.81.11.4
Locomotor activity1.21.86.42.52.11.2-1.1-0.80.6-0.40.20.3-0.90.50.50.2-1.7-2.32.30.91.5
Locomotor testing distance1.01.86.42.42.51.3-0.8-0.91.1-0.30.10.1-1.10.40.40.2-1.4-2.12.10.81.5
Locomotor testing rearing0.91.75.41.11.70.8-0.8-0.31.80.30.60.1-2.20.60.81.0-1.4-2.32.3-0.61.6
Locomotion in novel chamber0.50.72.10.3-1.2-0.10.30.8-0.10.60.10.7-0.50.81.20.9-1.5-1.11.20.70.8
Locomotion in novel chamber post-restriction1.11.74.41.60.01.3-2.0-1.31.1-1.72.1-1.6-0.6-1.6-0.9-1.5-0.8-0.30.3-0.8-1.5
Fecal boli incidents, locomotor time 10.10.20.6-0.7-0.8-0.10.50.30.20.4-0.1-0.10.2-0.10.2-0.10.20.7-0.70.2-0.4
Change in fecal boli incidents, locomotor task1.01.02.8-0.50.50.3-0.4-0.7-0.4-0.80.2-0.81.0-1.0-1.3-1.01.71.6-1.5-0.9-1.4
Time >=10cm from walls, locomotor time 12.42.65.4-0.7-2.2-1.61.32.0-1.41.5-1.01.9-0.21.72.02.3-1.5-1.41.41.31.9
Bouts of movement, locomotor time 10.60.73.1-1.20.2-0.3-0.30.0-0.9-0.0-0.50.11.0-0.1-0.7-0.41.81.3-1.3-0.9-0.6
Total resting periods, locomotor time 10.80.93.8-1.30.0-0.3-0.2-0.0-0.9-0.2-0.4-0.11.1-0.3-0.8-0.62.01.6-1.6-1.1-0.9
Rest time, locomotor task time 10.50.62.4-1.5-1.1-0.70.60.5-0.30.4-0.2-0.00.6-0.1-0.1-0.31.11.2-1.2-0.7-0.7
Distance moved, locomotor task time 10.30.41.20.91.10.8-0.5-1.00.5-1.00.6-0.7-0.6-0.7-0.8-0.40.1-0.10.1-0.3-0.4
Vertical activity count, locomotor time 10.10.30.80.90.50.8-0.3-0.60.2-0.60.5-0.3-0.5-0.4-0.3-0.3-0.7-0.50.50.3-0.0
Time >=10cm from walls, locomotor time 20.81.23.2-0.9-1.5-1.30.71.2-0.31.0-0.11.0-1.11.21.21.8-1.2-1.11.10.21.2
Bouts of movement, locomotor time 20.40.62.2-1.00.3-0.60.80.0-0.40.1-0.80.11.2-0.1-0.5-0.71.51.1-1.2-0.0-0.3
Total resting periods, locomotor time 20.30.61.9-1.00.2-0.70.90.3-0.50.4-1.10.41.30.1-0.2-0.51.41.1-1.10.2-0.0
Rest time, locomotor task time 22.73.47.5-2.6-2.4-2.42.72.0-2.01.9-2.31.61.91.21.11.01.11.8-1.71.40.4
Distance moved, locomotor task time 20.40.52.30.30.60.2-0.6-0.50.8-0.60.9-0.4-1.5-0.0-0.30.4-0.4-1.00.9-0.80.2
Vertical activity count, locomotor time 21.11.63.21.31.81.6-1.5-1.41.7-1.21.6-1.1-1.7-0.7-0.8-0.5-0.5-1.21.1-1.2-0.2
Light reinforcement 10.61.45.10.82.30.2-0.1-1.40.0-1.1-0.7-0.71.5-0.8-1.4-1.81.41.3-1.31.4-0.7
Light reinforcement 21.11.74.40.71.60.90.2-1.40.1-1.3-0.2-1.11.6-1.3-1.7-2.11.41.7-1.70.3-1.4
Bone: marrow area8.618.841.04.92.65.8-6.1-4.26.0-4.06.4-4.7-5.4-3.9-1.9-2.5-3.3-2.92.9-4.1-2.4
Bone: maximum diameter3.05.713.73.72.03.5-3.1-2.62.4-2.73.1-2.3-1.9-2.2-1.3-2.1-1.9-1.61.6-1.2-1.4
Bone: maximum force1.52.79.13.02.02.0-2.4-2.10.3-2.51.7-1.4-0.3-1.6-1.4-1.7-0.7-1.01.00.1-0.9
Bone: maximum moment1.52.78.52.91.92.0-2.5-2.10.2-2.41.8-1.4-0.4-1.5-1.4-1.6-0.6-1.01.0-0.1-0.9
Mean time between licks in bursts0.30.71.70.20.20.1-0.4-0.90.0-1.00.6-0.90.5-1.2-1.2-1.30.70.9-0.9-0.2-1.3
Mean num. licks in bursts0.50.91.8-0.01.11.0-0.1-0.90.2-1.00.3-0.90.5-0.8-1.2-1.21.41.0-1.0-1.2-1.0
Cd content in liver2.12.39.0-3.0-2.5-2.00.91.8-1.31.7-0.91.10.81.20.51.21.61.3-1.3-1.0-0.1
Co content in liver0.80.92.5-1.3-1.2-1.61.21.2-0.51.2-0.91.20.81.40.70.60.10.3-0.30.20.5
Cu content in liver0.20.30.6-0.30.30.4-0.4-0.40.4-0.40.5-0.6-0.1-0.7-0.5-0.70.40.6-0.6-0.8-0.8
Fe content in liver1.21.45.11.10.00.4-0.60.50.40.60.30.7-1.20.81.51.0-2.3-2.22.20.71.5
K content in liver0.50.42.31.2-0.11.2-0.4-0.30.6-0.30.7-0.1-0.3-0.10.3-0.4-1.5-0.70.70.5-0.1
Mg content in liver0.20.20.8-0.7-0.9-0.00.40.6-0.20.4-0.20.50.40.60.30.3-0.00.4-0.40.1-0.1
Mn content in liver0.40.51.91.0-0.40.4-0.40.3-0.40.00.10.70.20.70.70.1-1.4-1.11.20.80.6
Na content in liver0.70.83.31.20.10.50.60.21.20.6-0.00.4-0.80.91.00.3-1.8-1.21.11.10.8
Rb content in liver2.12.54.8-1.0-1.9-1.51.12.1-1.91.8-1.32.20.41.91.92.2-0.8-0.90.91.11.6
Se content in liver0.80.93.80.5-0.2-0.61.40.6-1.20.5-1.40.91.80.70.8-0.5-0.4-0.00.11.90.8
Sr content in liver0.40.30.90.60.5-0.3-0.4-0.80.5-1.00.8-0.6-0.5-0.4-0.8-0.20.10.0-0.0-0.5-0.6
Zn content in liver0.40.51.5-0.4-1.1-0.90.90.9-0.80.7-0.80.81.20.50.7-0.3-0.10.0-0.00.60.5
Bone: minimum diameter8.315.130.75.03.75.5-5.1-4.64.6-4.55.2-4.4-3.7-3.8-2.8-2.9-1.9-1.71.6-2.8-2.8
Time in familiar zone, hab. session 10.90.82.20.10.41.3-1.2-0.90.7-0.81.3-1.1-0.9-1.5-0.9-0.50.10.4-0.4-1.1-1.2
Time in novel zone, hab. session 10.90.92.1-0.5-0.4-1.41.20.9-1.00.7-1.41.21.31.40.60.10.4-0.20.20.81.1
Total zone transitions, hab. session 10.30.42.01.31.40.1-1.1-0.9-0.1-0.90.4-0.4-0.2-0.6-0.6-0.30.1-0.60.50.00.1
Total locomotion distance, hab. session 10.91.24.51.92.10.6-1.8-1.60.3-1.60.8-1.0-0.5-0.9-1.0-0.40.1-0.70.7-0.4-0.2
Locomotion velocity, hab. session 10.91.33.91.92.00.8-1.8-1.60.6-1.61.0-1.3-0.8-1.0-1.0-0.5-0.1-0.60.6-0.5-0.4
Time in familiar zone, hab. session 21.01.14.41.10.51.1-0.9-0.81.5-0.61.5-0.9-2.1-0.5-0.20.2-1.1-1.11.1-1.1-0.2
Time in novel zone, hab. session 20.90.94.1-1.0-0.6-0.80.50.5-1.70.1-1.10.62.00.0-0.2-0.51.21.2-1.10.6-0.2
Total zone transitions, hab. session 20.20.20.80.80.9-0.6-0.2-0.50.2-0.40.2-0.1-0.5-0.2-0.20.1-0.2-0.60.60.30.3
Total locomotion distance, hab. session 20.91.23.51.11.90.6-1.1-1.60.5-1.50.7-1.20.0-1.4-1.5-1.20.90.5-0.5-0.6-1.0
Locomotion velocity, hab. session 20.91.22.81.01.70.5-0.9-1.60.4-1.50.6-1.20.1-1.4-1.5-1.30.90.6-0.6-0.4-1.0
Novel to familiar place preference ratio0.70.83.70.90.91.1-1.9-0.80.4-1.11.0-0.60.2-0.6-0.7-1.20.0-0.30.3-0.9-0.6
Novelty place preference0.40.42.50.70.60.7-1.6-0.50.2-0.80.7-0.30.3-0.2-0.4-0.9-0.1-0.50.5-0.7-0.2
Time in novel zone, NPP test0.30.42.30.80.50.6-1.5-0.30.2-0.60.6-0.10.20.0-0.1-0.6-0.3-0.80.8-0.60.1
Total zone transitions, NPP test0.30.52.51.61.30.2-0.1-0.8-0.4-0.7-0.2-0.20.2-0.4-0.4-0.4-0.2-0.40.41.20.3
Total locomotion distance, NPP test0.71.02.51.51.61.0-1.2-1.40.3-1.50.9-1.1-0.7-1.1-1.1-0.70.2-0.30.3-0.4-0.5
Locomotion velocity, NPP test0.91.34.01.32.01.0-0.8-1.70.1-1.70.4-1.30.2-1.5-1.5-1.31.00.6-0.6-0.2-1.0
Intraocular pressure1.11.65.30.32.30.80.2-1.30.4-1.3-0.6-1.20.9-1.3-1.3-1.51.91.6-1.6-0.2-0.9
Delta distance traveled before/after self-admin0.30.30.80.70.70.0-0.3-0.10.2-0.1-0.10.3-0.70.50.20.8-0.5-0.90.90.20.7
Delta ambulatory time before/after self-admin0.20.20.70.80.90.5-0.8-0.60.5-0.60.4-0.4-0.4-0.3-0.4-0.0-0.2-0.30.3-0.2-0.1
Parametrial fat weight0.30.62.4-0.6-1.50.1-0.8-0.1-0.4-0.61.1-0.50.0-0.7-0.7-0.50.40.8-0.7-1.3-1.3
Pavlov. Cond. lever latency1.11.44.3-2.1-1.6-1.10.30.7-1.40.3-0.4-0.01.4-0.5-0.5-0.41.81.9-1.9-0.9-1.1
Pavlov. Cond. magazine entry latency1.62.15.72.42.02.0-1.7-1.42.3-1.11.4-1.0-1.7-0.5-0.2-0.4-1.5-1.41.4-0.4-0.0
Pavlov. Cond. change in total contacts1.61.64.31.92.01.8-1.1-1.02.1-0.60.9-0.5-1.90.20.10.3-1.4-1.51.5-0.30.4
Pavlov. Cond. index score1.62.06.32.52.01.9-1.2-1.22.1-0.91.1-0.7-1.6-0.10.0-0.1-1.8-1.81.70.10.4
Pavlov. Cond. latency score1.41.86.12.51.91.6-0.9-1.12.0-0.70.9-0.5-1.40.00.2-0.2-1.9-1.81.80.40.6
Pavlov. Cond. lever contacts1.01.23.11.61.31.1-0.4-0.61.7-0.20.7-0.1-1.80.40.40.6-1.6-1.71.60.30.8
Pavlov. Cond. magazine entry number1.21.54.1-2.0-1.7-1.81.31.1-2.00.6-0.90.71.60.0-0.0-0.11.41.2-1.20.2-0.2
Pavlov. Cond. intertrial magazine entries1.92.25.81.72.42.3-2.0-1.90.9-1.70.9-1.7-0.0-1.7-1.5-1.80.40.6-0.6-0.1-1.3
Pavlov. Cond. lever-magazine prob. diff.1.61.96.22.51.92.0-1.2-1.22.0-0.91.1-0.7-1.6-0.10.0-0.1-1.8-1.71.60.10.4
Pavlov. Cond. response bias1.72.15.92.41.92.0-1.5-1.22.2-0.81.2-0.8-1.9-0.10.10.1-1.9-1.71.6-0.00.3
Pavlov. Cond. lever latency0.50.61.9-1.4-0.6-0.40.70.3-0.90.1-0.50.20.8-0.1-0.5-0.21.41.3-1.3-0.4-0.6
Pavlov. Cond. magazine entry latency2.42.85.6-1.1-2.3-2.42.22.1-1.42.0-1.61.90.41.82.02.0-1.0-0.60.61.61.7
Pavlov. Cond. change in total contacts0.60.93.11.30.20.1-0.2-0.11.50.20.7-0.3-1.30.30.90.4-1.8-1.61.60.30.8
Pavlov. Cond. index score0.81.02.90.7-0.5-0.70.40.60.40.8-0.10.6-0.90.91.31.2-1.7-1.61.60.81.3
Pavlov. Cond. latency score1.11.43.50.6-0.7-1.00.70.90.11.1-0.40.9-0.81.21.71.5-1.9-1.71.81.11.6
Pavlov. Cond. lever contacts0.30.51.61.30.80.4-0.6-0.30.8-0.00.3-0.2-0.60.10.40.2-1.1-1.11.10.60.6
Pavlov. Cond. magazine entry number3.64.48.81.22.53.0-2.5-2.61.8-2.52.0-2.4-0.5-2.3-2.5-2.51.21.0-1.0-2.0-2.3
Pavlov. Cond. intertrial magazine entries9.213.822.22.74.04.7-3.9-4.73.6-4.74.1-4.6-1.8-4.4-4.2-4.21.11.2-1.2-3.5-4.1
Pavlov. Cond. lever-magazine prob. diff.0.81.12.80.6-0.7-0.80.50.80.20.9-0.20.7-0.71.01.41.2-1.7-1.51.50.91.4
Pavlov. Cond. response bias0.30.51.71.00.1-0.1-0.20.10.30.30.10.2-0.50.30.70.5-1.3-1.21.20.80.8
Time in closed arm before self-admin0.40.51.70.80.70.60.10.1-0.20.1-0.30.7-0.50.70.50.6-0.8-1.31.30.61.2
Time in closed arm after self-admin0.60.62.0-0.4-1.1-0.80.20.8-0.80.40.10.8-0.80.70.71.4-0.8-0.91.0-0.10.7
Time in open arm before self-admin1.41.55.6-1.0-1.8-2.41.31.5-1.41.2-1.01.40.71.31.21.0-0.4-0.20.21.30.9
Time in open arm after self-admin0.30.31.0-0.20.2-0.10.5-0.20.4-0.0-0.3-0.50.8-0.4-0.3-0.90.71.0-1.00.1-0.6
Bone: periosteal estimation5.912.425.04.93.14.9-5.0-3.94.0-3.84.8-3.5-3.5-3.0-2.0-2.4-2.5-2.52.5-2.4-1.8
Bone: periosteal perimeter2.94.914.43.81.63.2-2.7-2.32.5-2.32.9-1.9-1.8-1.5-0.9-1.8-2.3-2.12.0-0.9-0.9
Bone: post-yield work1.11.73.61.80.81.4-1.8-1.21.4-1.31.9-1.3-1.7-1.2-0.4-0.2-1.1-1.31.3-1.0-0.4
Progressive ratio test 1 active lever presses2.02.57.92.72.81.8-1.9-2.11.8-2.01.2-1.5-1.3-1.3-1.2-0.6-0.4-0.70.7-0.2-0.5
Progressive ratio test 1 breakpoint2.32.98.92.83.01.9-2.1-2.42.0-2.31.3-1.7-1.3-1.5-1.4-0.8-0.3-0.60.6-0.4-0.7
Progressive ratio test 1 inactive lever presses2.53.69.93.12.91.8-2.5-2.52.0-2.52.0-1.7-1.9-1.3-1.3-0.9-0.6-1.31.3-1.0-0.6
Progressive ratio test 2 active lever presses2.83.27.12.72.52.2-1.8-2.52.3-2.31.6-2.2-1.1-2.0-1.5-1.5-0.3-0.00.0-0.9-1.4
Progressive ratio test 2 breakpoint3.03.57.32.72.52.3-1.9-2.52.4-2.41.8-2.3-1.3-2.0-1.6-1.5-0.3-0.10.0-1.0-1.4
Progressive ratio test 2 inactive lever presses2.03.39.22.23.01.8-2.0-2.61.6-2.51.3-2.0-0.3-1.9-2.0-1.80.90.5-0.5-1.2-1.5
Incentive Sensitization - Responses1.21.63.11.81.21.6-0.9-1.71.7-1.61.4-1.7-1.0-1.5-1.0-1.3-0.50.1-0.1-0.7-1.2
Incentive Sensitization - Breakpoint1.21.63.01.71.11.5-0.8-1.71.7-1.51.4-1.7-1.0-1.5-1.0-1.3-0.60.0-0.0-0.8-1.2
Sum of active levers in priming session hrs 5-61.31.22.6-0.5-0.2-1.01.11.1-0.31.6-1.51.40.61.51.31.0-0.2-0.40.41.61.5
Progressive ratio0.10.10.80.2-0.90.40.1-0.0-0.0-0.10.5-0.4-0.1-0.5-0.0-0.5-0.40.3-0.3-0.1-0.6
Food seeking constrained by brief footshock2.02.412.01.10.61.2-1.3-1.22.3-1.12.4-1.4-3.5-0.8-0.50.8-1.3-1.31.2-2.0-0.6
Seeking ratio, punishment vs. effort0.81.24.31.11.71.1-1.2-1.11.8-0.91.2-0.8-2.1-0.3-0.50.6-0.5-1.01.0-1.0-0.0
Retroperitoneal fat weight0.52.03.80.71.61.0-1.9-1.91.0-1.91.5-1.7-0.7-1.9-2.0-1.10.90.7-0.7-1.1-1.6
Reaction time number correct0.40.83.0-0.3-0.9-1.00.70.7-1.60.6-1.20.81.70.30.5-0.10.30.5-0.51.50.4
Reaction time mean minus median0.20.42.5-1.6-0.8-0.20.30.6-0.40.6-0.40.20.20.10.10.30.70.9-0.9-0.2-0.2
Reaction time mean minus median AUC0.20.61.8-1.1-1.0-0.20.31.0-1.30.9-0.90.91.20.60.60.10.20.5-0.51.00.3
Reaction time num false alarms1.82.59.23.01.91.9-1.5-1.62.1-1.51.6-1.2-1.3-1.0-0.3-1.1-2.0-1.71.7-0.1-0.1
Reaction time num false alarms AUC1.72.68.62.91.82.1-1.7-1.82.1-1.61.8-1.4-1.2-1.1-0.5-1.3-1.8-1.51.5-0.2-0.4
Reaction time trials correct on left0.40.83.0-0.3-0.9-1.00.70.7-1.60.6-1.20.81.70.30.5-0.10.30.5-0.51.50.4
Reaction time trials on left0.40.83.1-0.3-0.9-0.90.60.7-1.60.5-1.20.81.80.20.4-0.20.40.6-0.51.50.3
Reaction time mean0.50.92.7-1.2-1.4-0.30.31.4-0.91.4-0.71.1-0.30.81.21.6-0.4-0.20.20.40.8
Reaction time mean AUC0.91.43.9-1.5-1.5-0.60.51.7-0.91.7-0.91.4-0.31.21.52.0-0.4-0.30.30.51.1
Median of all reaction times0.81.13.7-1.0-1.3-0.40.31.4-0.91.4-0.71.3-0.51.01.41.9-0.6-0.50.60.61.1
Reaction time omissions0.71.02.3-0.50.30.6-1.1-0.8-0.0-1.10.8-1.00.1-1.4-1.3-0.81.31.2-1.2-1.3-1.5
Reaction time false alarm rate2.02.76.72.51.82.1-1.5-1.62.6-1.42.0-1.4-2.1-0.9-0.4-0.8-1.8-1.71.7-0.9-0.2
Reaction time premature initiation rate0.91.24.41.22.11.4-1.2-1.40.9-1.30.7-1.00.1-0.9-1.2-1.40.70.2-0.2-0.7-0.8
Reaction time premature initiations0.40.82.60.91.40.9-0.7-1.10.2-1.10.1-0.71.1-0.8-1.0-1.60.80.6-0.60.2-0.7
Std. dev. reaction times0.20.42.6-1.6-1.3-0.00.00.9-0.40.7-0.10.4-0.20.20.40.70.40.5-0.5-0.6-0.1
Reaction time trials completed0.40.83.1-0.3-0.9-0.90.60.7-1.60.5-1.20.81.80.20.4-0.20.40.6-0.51.50.3
Reaction time trials AUC0.40.72.9-0.3-1.0-0.90.50.6-1.60.4-1.10.71.70.20.4-0.20.40.6-0.51.40.3
Run reversals in cocaine runway, females1.11.15.1-1.9-0.3-0.10.90.3-1.10.1-0.80.20.70.0-0.80.02.31.9-1.9-0.5-0.7
Run reversals in cocaine runway, males0.20.20.5-0.5-0.5-0.70.10.3-0.40.4-0.2-0.10.6-0.1-0.0-0.20.40.6-0.6-0.3-0.3
Latency to leave start box in cocaine runway0.30.30.9-0.1-0.1-0.90.70.5-0.20.4-0.60.7-0.10.80.60.9-0.1-0.40.40.60.8
Latency to leave start box in cocaine runway, F1.01.22.70.2-0.0-1.21.30.9-0.60.9-1.31.3-0.11.41.31.4-0.6-1.01.01.41.6
Latency to leave start box in cocaine runway, M0.10.10.3-0.5-0.4-0.4-0.10.00.4-0.00.4-0.1-0.5-0.1-0.10.10.10.1-0.1-0.5-0.3
Std. dev. time between licks in bursts0.20.30.9-0.40.4-0.70.2-0.40.2-0.3-0.1-0.4-0.0-0.5-0.70.00.90.9-0.9-0.1-0.6
Total sessions with >9 infusions0.50.64.31.42.10.50.1-0.90.3-0.7-0.8-0.20.1-0.2-0.40.10.20.0-0.01.10.4
Short access day 1 total inactive lever presses1.62.16.92.22.61.8-1.7-2.01.4-2.11.2-1.5-1.1-1.3-1.4-0.60.1-0.50.4-1.2-0.7
Short access day 10 total inactive lever presses0.41.03.0-0.11.20.7-1.0-0.90.0-1.00.6-0.60.7-0.7-1.2-1.61.70.8-0.8-1.3-1.1
Short access day 1 total infusions0.81.07.02.12.60.9-0.4-1.10.5-0.9-0.8-0.2-0.1-0.1-0.30.4-0.3-0.50.51.20.7
Short access day 10 total infusions2.63.310.12.73.22.0-2.2-2.61.9-2.41.5-1.9-1.3-1.7-1.7-1.1-0.3-0.50.5-0.9-0.9
Short access total infusions1.31.67.02.52.61.6-1.4-1.61.3-1.50.6-0.9-1.0-0.6-0.6-0.2-0.6-1.01.0-0.00.2
Short access day 1 locomotion2.53.115.92.54.02.2-1.3-2.51.3-2.20.1-1.70.1-1.6-2.0-1.40.90.6-0.70.2-0.9
Short access day 10 total locomotion2.85.314.22.63.83.4-2.8-3.02.9-2.52.2-2.5-2.3-2.1-2.0-1.2-0.1-0.60.5-1.6-1.3
Short access total locomotion2.83.314.62.53.82.5-1.7-2.62.0-2.20.9-2.0-1.1-1.7-1.9-1.00.40.0-0.1-0.4-0.9
One hour access (0.3 mA shock)0.50.61.61.30.80.5-0.7-0.81.3-0.70.8-0.7-1.1-0.5-0.2-0.0-0.7-0.60.6-0.3-0.1
Compulsive drug intake1.21.43.5-0.6-1.9-1.61.11.5-1.01.1-0.71.40.21.51.51.2-0.7-0.80.91.11.2
One hour access (shock baseline)1.01.63.31.41.81.5-1.3-1.81.4-1.51.2-1.6-0.9-1.5-1.3-1.0-0.00.2-0.2-1.1-1.1
Social response proportion0.10.10.6-0.4-0.2-0.30.10.5-0.60.3-0.50.50.80.30.4-0.20.40.1-0.10.30.3
Social responses0.30.41.40.90.80.2-0.7-0.10.3-0.10.10.4-0.30.50.50.2-0.6-1.21.20.40.9
Social time0.30.41.3-1.1-1.20.11.00.9-0.20.8-0.40.5-0.10.50.80.6-0.10.3-0.30.30.3
Soleus weight0.10.31.31.20.90.70.2-0.30.30.0-0.40.20.40.40.2-0.5-0.5-0.50.50.90.5
Bone: stiffness0.91.56.32.50.71.3-1.6-1.20.3-1.41.4-0.8-0.7-0.9-0.3-0.9-1.7-1.51.60.7-0.1
Tibialis anterior weight0.72.56.5-0.72.00.9-0.6-1.50.8-1.20.2-1.21.1-1.2-2.2-2.02.52.2-2.2-1.4-1.8
Time to tail flick, vehicle, before self-admin0.70.74.5-0.3-2.1-0.10.61.1-0.10.80.30.5-0.10.51.20.6-1.2-0.70.80.70.4
Time to tail flick, vehicle, after self-admin0.30.31.80.4-0.40.40.2-0.2-0.3-0.20.0-0.41.2-0.7-0.2-1.3-0.20.6-0.50.7-0.6
Time to tail flick, test, before self-admin0.30.41.0-0.8-0.6-0.6-0.60.60.20.70.30.3-0.70.60.61.0-0.1-0.60.5-0.80.4
Time to tail flick, test, after self-admin0.10.10.40.10.20.2-0.6-0.10.40.10.2-0.30.5-0.20.0-0.7-0.0-0.00.00.2-0.1
Delta time to tail flick, vehicle, before/after SA1.31.32.60.41.10.7-1.1-1.40.7-1.31.1-1.4-0.0-1.4-1.5-1.60.80.9-0.9-1.4-1.5
Delta time to tail flick, test, before/after SA0.10.10.50.6-0.30.7-0.3-0.0-0.1-0.00.2-0.10.5-0.20.2-0.7-0.5-0.10.20.5-0.1
Tibia length0.20.63.31.60.20.20.2-0.1-0.8-0.2-0.50.40.70.20.4-0.2-1.0-0.90.91.80.8
Ambulatory time before self-admin0.81.22.60.0-1.4-0.81.31.2-0.51.2-0.81.10.51.11.50.4-1.5-1.01.01.61.3
Ambulatory time after self-admin0.40.51.80.8-0.1-0.1-0.00.30.30.4-0.10.4-0.20.60.80.4-1.3-1.21.20.80.9
Bone: tissue strength1.01.03.20.2-0.6-0.90.90.9-1.60.7-1.21.20.70.81.10.9-0.6-0.60.71.81.2
Total heroin consumption1.41.67.11.4-0.20.20.30.50.70.8-0.10.7-0.81.01.60.3-2.7-2.02.01.61.6
Bone: trabecular number0.71.23.41.80.71.8-1.0-1.40.9-1.51.4-1.3-0.6-1.1-0.9-1.1-0.9-0.30.3-0.0-1.0
Bone: trabecular spacing0.30.41.5-1.0-0.5-1.10.60.80.00.9-0.50.6-0.50.60.71.20.1-0.10.1-0.10.6
Bone: trabecular thickness1.31.63.61.11.21.2-1.0-1.60.8-1.71.1-1.50.4-1.6-1.6-1.90.60.9-0.9-0.6-1.7
Bone: trabecular tissue density0.71.05.40.2-0.2-1.10.80.1-1.8-0.2-1.30.52.3-0.3-0.3-0.80.80.8-0.71.80.0
Water consumed over 24 hours0.10.10.70.50.70.2-0.2-0.6-0.1-0.80.2-0.20.0-0.2-0.5-0.4-0.0-0.10.10.4-0.1
Number of responses in last shaping day0.10.10.80.30.90.4-0.2-0.30.2-0.1-0.3-0.20.3-0.1-0.2-0.30.10.1-0.10.10.1