Kiaa0930

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R² and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

#	Tissue	Modality	RNA phenotype	h²	h² SE	h² P	xQTL R²	BLUP R²	ENET R²	LASSO R²	xQTL P	BLUP P	ENET P	LASSO P
1	Liver	gene expression	Kiaa0930	0.2	0.08	0.0e+00	0.16	0.11	0.15	0.13	6.8e-17	5.2e-12	2.5e-16	2.0e-14
2	pVTA	gene expression	Kiaa0930	0.21	0.09	1.1e-15	0.12	0.18	0.18	0.18	2.8e-10	1.5e-14	1.9e-14	1.6e-14
3	PL	gene expression	Kiaa0930	0.09	0.05	1.8e-07	0.07	0.06	0.06	0.07	6.3e-08	3.6e-07	3.1e-07	1.1e-07
4	Brain	gene expression	Kiaa0930	0.2	0.08	5.2e-15	0.17	0.15	0.16	0.17	1.2e-15	5.0e-14	3.1e-15	1.3e-15
5	BLA	gene expression	Kiaa0930	0.18	0.09	2.2e-06	0.1	0.09	0.09	0.09	5.6e-06	1.9e-05	2.1e-05	1.8e-05
6	NAcc	gene expression	Kiaa0930	0.19	0.07	0.0e+00	0.22	0.22	0.21	0.21	3.8e-32	8.1e-32	2.0e-30	9.9e-32
7	LHb	gene expression	Kiaa0930	0.26	0.15	5.4e-03	0.05	0.05	0.04	0.05	2.3e-02	2.1e-02	4.6e-02	2.6e-02
8	Adipose	gene expression	Kiaa0930	0.33	0.11	0.0e+00	0.25	0.26	0.28	0.28	4.2e-27	1.1e-28	1.5e-30	2.7e-31
9	IL	gene expression	Kiaa0930	0.26	0.14	4.8e-03	0	0.03	0.02	0.01	3.2e-01	6.0e-02	9.2e-02	1.4e-01
10	Adipose	mRNA stability	Kiaa0930	0.16	0.08	5.1e-13	0.08	0.12	0.1	0.11	3.9e-09	6.5e-13	9.9e-12	6.7e-12

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait	Avg chi² ratio	Avg chi²	Max chi²	1	2	3	4	5	6	7	8	9	10
Bone: apparent density	0.4	0.7	1.9	-1.4	-1.3	0.8	0.8	1.0	1.0	-0.8	0.3	-0.2	-0.2
Area under the delay curve	2.1	3.3	5.0	-1.5	-2.1	2.2	2.1	2.1	2.1	-1.9	-0.6	-1.4	-1.4
BMI with tail	0.5	1.8	8.5	2.9	2.0	-0.8	-0.8	-0.7	-0.7	0.2	-1.1	-0.9	-1.2
BMI without tail	0.0	0.2	0.7	0.8	0.7	-0.4	-0.5	-0.2	-0.2	0.2	0.1	0.0	-0.2
Body weight	0.6	2.5	8.1	2.8	2.4	-1.5	-1.6	-1.5	-1.5	1.1	-0.6	0.1	-0.2
Weight adjusted by age	0.3	0.8	1.3	0.9	1.1	-1.1	-1.1	-1.1	-1.1	0.9	0.3	0.6	0.5
Bone surface	0.2	0.4	0.8	-0.7	-0.8	0.6	0.6	0.9	0.9	-0.7	-0.1	-0.3	-0.3
Bone volume	0.2	0.3	0.8	-0.9	-0.8	0.5	0.5	0.7	0.7	-0.5	0.3	-0.1	-0.0
Breakpoint value in progressive ratio session	0.1	0.1	0.5	0.7	0.5	-0.3	-0.3	-0.2	-0.2	0.1	-0.2	-0.1	-0.2
Number of licking bursts	0.1	0.4	1.0	-1.0	-0.3	-0.1	-0.1	-0.1	-0.1	0.4	1.0	0.8	0.9
Context. condit. distance diff. score	1.1	1.3	4.1	2.0	1.7	-1.2	-1.2	-0.8	-0.8	1.1	-1.0	0.2	0.1
Locomotion velocity, session 1	0.5	0.6	1.0	0.9	0.8	-0.8	-0.9	-0.7	-0.7	0.8	-1.0	0.5	0.3
Locomotion distance, session 1	0.1	0.2	0.7	-0.8	-0.5	0.2	0.2	0.3	0.3	0.1	-0.6	0.2	0.3
Locomotion velocity, session 2	2.6	3.1	5.0	2.1	2.2	-1.9	-1.9	-2.0	-2.0	1.8	0.5	1.1	0.9
Locomotion distance, session 2	0.3	0.4	0.7	-0.0	-0.5	0.6	0.7	0.5	0.5	-0.7	-0.8	-0.7	-0.7
Locomotion velocity, session 3	3.1	3.6	5.4	1.5	2.3	-2.0	-2.0	-2.2	-2.2	2.3	0.9	1.6	1.5
Locomotion distance, session 3	1.7	1.9	3.6	-0.1	1.0	-1.3	-1.3	-1.4	-1.4	1.5	1.9	1.6	1.7
Stereotopy head waving bouts, day 3	0.5	0.6	2.8	1.7	1.1	-0.4	-0.4	-0.4	-0.4	0.3	-1.0	-0.5	-0.6
Stereotopy head waving duration, day 3	1.3	1.6	4.7	2.2	1.9	-1.2	-1.2	-1.1	-1.1	1.1	-1.0	0.0	-0.2
Locomotion velocity, session 7	1.3	1.5	2.6	1.0	1.6	-1.2	-1.2	-1.3	-1.3	1.5	0.7	0.9	0.9
Locomotion distance, session 7	0.0	0.0	0.1	-0.1	0.1	0.2	0.2	-0.1	-0.1	0.3	0.3	0.2	0.3
Stereotopy head waving bouts, day 7	3.8	4.4	7.2	2.0	2.5	-2.7	-2.7	-2.2	-2.2	2.3	0.5	1.6	1.4
Stereotopy head waving duration, day 7	2.2	2.7	4.5	1.4	1.9	-2.1	-2.1	-1.7	-1.7	1.8	0.6	1.4	1.2
Locomotion velocity, session 8	4.3	5.2	12.0	3.5	3.2	-2.6	-2.6	-2.3	-2.3	1.9	-1.5	0.6	0.3
Locomotion distance, session 8	1.0	1.5	3.5	1.9	1.7	-1.4	-1.3	-1.1	-1.1	1.2	-0.5	0.6	0.4
Degree of sensitization distance	1.8	1.9	4.4	0.8	-0.4	1.4	1.4	1.1	1.1	-1.3	-2.1	-1.8	-1.8
Degree of sensitization stereotypy	2.7	3.1	5.3	1.4	2.0	-2.3	-2.3	-1.8	-1.8	1.9	0.7	1.5	1.3
Conditioned locomotion	0.0	0.0	0.3	-0.2	-0.0	0.2	0.2	0.2	0.2	0.1	0.5	-0.0	0.1
Cocaine response after cond. corrected	0.3	0.5	1.1	-0.8	-0.1	-0.4	-0.4	-0.4	-0.4	0.6	0.9	1.0	1.0
Cocaine response after cond. not corrected	1.0	1.5	3.0	-1.0	0.2	-1.0	-1.0	-0.9	-0.9	1.2	1.6	1.7	1.7
Cocaine response before conditioning	0.2	0.2	0.6	-0.6	-0.1	-0.3	-0.3	-0.2	-0.2	0.4	0.7	0.5	0.6
Saline control response	0.4	0.6	1.4	-0.6	0.1	-0.5	-0.6	-0.5	-0.5	0.8	0.9	1.2	1.2
Bone: connectivity density	0.2	0.2	0.7	-0.9	-0.7	0.3	0.3	0.6	0.6	-0.5	0.2	-0.1	-0.1
Bone: cortical apparent density	1.1	1.8	2.8	-1.1	-1.5	1.7	1.6	1.5	1.5	-1.3	-0.5	-1.0	-0.9
Bone: cortical area	0.4	0.6	1.2	1.0	1.1	-0.9	-0.9	-0.8	-0.8	0.8	0.4	0.4	0.4
Bone: cortical porosity	0.0	0.0	0.2	-0.2	0.1	-0.2	-0.2	0.1	0.1	0.1	0.4	0.1	0.0
Bone: cortical porosity	0.0	0.0	0.1	0.1	0.3	-0.3	-0.4	0.0	0.0	0.2	0.2	0.0	-0.1
Bone: cortical thickness	0.4	0.6	0.8	-0.5	-0.8	0.9	0.8	0.9	0.9	-0.8	-0.7	-0.8	-0.7
Bone: cortical thickness	0.8	1.0	2.0	0.3	-0.3	1.0	1.0	0.8	0.8	-0.9	-1.4	-1.4	-1.4
Bone: cortical tissue density	1.0	1.5	2.5	-0.9	-1.4	1.6	1.5	1.4	1.4	-1.3	-0.6	-1.0	-0.9
Condit. Reinf. active minus inactive responses	1.2	1.4	2.2	-1.2	-1.5	1.4	1.4	1.3	1.3	-1.3	-0.5	-0.9	-0.8
Condit. Reinf. active-inactive response ratio	1.5	1.6	2.6	-1.2	-1.6	1.5	1.4	1.5	1.5	-1.3	-0.6	-0.9	-0.8
Condit. Reinf. active responses	0.7	0.9	1.8	-1.3	-1.4	1.1	1.1	1.0	1.0	-0.9	0.2	-0.4	-0.3
Condit. Reinf. inactive responses	0.1	0.1	0.3	-0.3	-0.2	-0.1	-0.1	-0.2	-0.2	0.1	0.6	0.4	0.4
Incentive salience index mean	0.5	0.6	1.5	-1.2	-1.1	0.9	0.9	0.7	0.7	-0.7	0.0	-0.3	-0.2
Condit. Reinf. lever presses	0.1	0.2	0.5	-0.7	-0.1	-0.0	-0.0	-0.3	-0.3	0.4	0.5	0.4	0.6
Condit. Reinf. active minus inactive responses	0.2	0.3	1.1	0.7	0.3	0.1	0.0	0.1	0.1	-0.4	-1.1	-0.7	-0.7
Condit. Reinf. active-inactive response ratio	0.0	0.1	0.4	0.1	0.1	-0.0	-0.1	-0.2	-0.2	-0.1	-0.7	0.0	-0.1
Condit. Reinf. active responses	0.5	0.7	3.0	1.7	1.0	-0.3	-0.4	-0.2	-0.2	-0.2	-1.2	-0.9	-1.0
Condit. Reinf. inactive responses	0.5	0.8	3.3	1.8	1.1	-0.3	-0.3	-0.1	-0.1	-0.0	-1.0	-1.0	-1.0
Condit. Reinf. lever presses	0.5	0.8	2.7	1.7	1.3	-0.9	-1.0	-0.8	-0.8	0.5	-0.4	-0.0	-0.1
Condit. Reinf. lever reinforcers received	0.4	0.5	1.9	1.4	0.7	-0.1	-0.2	0.0	0.0	-0.3	-1.1	-0.9	-0.9
Conditioned reinforcement - actives	0.0	0.2	0.3	-0.1	-0.4	0.4	0.5	0.5	0.5	-0.4	-0.1	-0.4	-0.3
Conditioned reinforcement - inactives	0.1	0.2	1.3	0.4	0.2	-0.0	0.1	0.0	0.0	-0.1	-1.1	-0.2	-0.3
Conditioned locomotion	0.9	1.3	1.9	0.6	1.3	-1.4	-1.4	-1.3	-1.3	1.3	0.6	1.2	1.0
Patch foraging indifference point 0 sec	0.0	0.1	0.4	-0.6	-0.3	-0.2	-0.1	-0.1	-0.1	0.0	0.3	0.5	0.5
Patch foraging indifference point AUC	0.2	0.4	0.6	-0.2	-0.6	0.7	0.7	0.7	0.7	-0.7	-0.8	-0.7	-0.6
Delay disc. indifference point, 0s delay	0.1	0.1	0.1	0.1	-0.2	0.3	0.3	0.4	0.4	-0.2	0.0	-0.2	-0.3
Delay disc. indifference point, 16s delay	2.2	3.2	5.7	-1.9	-2.4	2.0	2.1	2.1	2.1	-1.7	-0.3	-1.0	-0.9
Delay disc. indifference point, 2s delay	1.5	1.7	2.4	-1.0	-1.4	1.5	1.4	1.5	1.5	-1.4	-0.6	-1.2	-1.1
Delay disc. indifference point, 24s delay	0.2	0.4	0.6	0.0	-0.4	0.7	0.6	0.6	0.6	-0.8	-0.3	-0.8	-0.8
Delay disc. indifference point, 4s delay	3.9	4.1	5.8	-1.2	-2.2	2.4	2.3	2.3	2.3	-2.2	-1.7	-1.7	-1.8
Delay disc. indifference point, 8s delay	1.6	2.6	4.2	-1.2	-1.8	2.0	1.9	1.8	1.8	-1.8	-0.2	-1.4	-1.3
Indifference point function ln k	0.8	2.4	3.2	1.0	1.6	-1.7	-1.6	-1.8	-1.8	1.7	1.1	1.4	1.3
Indifference point function log k	0.8	2.4	3.2	1.0	1.6	-1.7	-1.6	-1.8	-1.8	1.7	1.1	1.4	1.3
Patch foraging total patch changes 0 sec	0.1	0.2	0.6	-0.8	-0.3	-0.3	-0.2	-0.1	-0.1	0.2	0.4	0.7	0.8
Patch foraging total patch changes 12 sec	0.2	0.3	0.9	0.1	-0.2	0.4	0.4	0.5	0.5	-0.4	-0.9	-0.7	-0.6
Patch foraging total patch changes 18 sec	0.2	0.5	1.8	-1.3	-1.0	0.7	0.7	0.7	0.7	-0.5	-0.3	-0.0	0.1
Patch foraging total patch changes 24 sec	0.4	1.3	1.9	0.1	0.9	-1.2	-1.2	-1.2	-1.2	1.3	1.1	1.4	1.4
Patch foraging total patch changes 6 sec	0.3	0.4	0.8	-0.8	-0.9	0.6	0.7	0.6	0.6	-0.8	-0.7	-0.3	-0.3
Patch foraging time to switch 0 sec	0.0	0.0	0.1	-0.1	0.1	0.1	0.1	0.3	0.3	0.0	0.2	-0.3	-0.3
Patch foraging water rate 0 sec	0.3	1.0	1.7	1.0	1.1	-1.2	-1.2	-1.3	-1.3	0.8	0.2	0.8	0.7
Patch foraging water rate 12 sec	0.9	3.7	6.1	0.1	1.2	-2.0	-2.1	-2.0	-2.0	2.0	2.0	2.5	2.2
Patch foraging water rate 18 sec	0.1	0.3	0.5	0.2	0.3	-0.6	-0.5	-0.7	-0.7	0.3	0.5	0.7	0.6
Patch foraging water rate 24 sec	0.7	1.0	1.6	1.3	1.1	-1.3	-1.2	-1.2	-1.2	0.8	0.3	0.8	0.5
Patch foraging water rate 6 sec	0.3	0.5	1.3	-0.5	0.0	-0.6	-0.6	-0.4	-0.4	0.6	1.1	1.0	1.0
Seeking ratio, delayed vs. immediate footshock	0.2	0.3	1.3	-0.9	-0.5	-0.1	-0.1	0.0	0.0	-0.1	1.1	0.5	0.5
Distance traveled before self-admin	0.0	0.1	0.7	-0.8	-0.4	0.0	0.2	0.1	0.1	0.1	0.1	0.1	0.3
Distance traveled after self-admin	0.4	0.7	1.2	-0.2	0.7	-1.1	-0.8	-1.0	-1.0	0.9	0.3	0.9	0.9
Extensor digitorum longus weight	0.5	1.9	3.3	1.4	1.8	-1.5	-1.5	-1.7	-1.7	1.4	0.7	1.0	0.9
Bone: elastic displacement	1.5	1.9	2.6	0.9	1.2	-1.6	-1.6	-1.6	-1.6	1.5	0.6	1.5	1.3
Bone: elastic work	3.1	4.1	7.3	2.4	2.7	-2.3	-2.4	-2.2	-2.2	2.1	0.2	1.3	0.9
Bone: endosteal estimation	2.5	6.1	10.3	2.9	3.2	-2.8	-2.8	-2.7	-2.7	2.5	0.9	1.7	1.3
Bone: endosteal perimeter	3.5	8.6	11.8	2.3	3.4	-3.3	-3.4	-3.2	-3.2	3.2	2.2	2.5	2.3
Epididymis fat weight	0.2	0.9	2.4	1.4	0.4	0.6	0.5	0.4	0.4	-0.7	-1.0	-1.4	-1.5
Delta time in closed arm before/after self-admin	1.7	1.6	2.4	-0.8	-1.2	1.2	1.4	1.3	1.3	-1.2	-1.6	-1.2	-1.2
Delta time in open arm before/after self-admin	4.5	5.3	7.1	0.8	2.0	-2.6	-2.6	-2.5	-2.5	2.7	1.5	2.6	2.5
Diff in mean of infusions in LGA sessions	0.9	1.5	2.3	0.1	-0.8	1.2	1.2	1.3	1.3	-1.4	-1.5	-1.5	-1.5
Delay discount exponential model param	2.6	3.6	5.4	1.5	2.2	-2.3	-2.2	-2.2	-2.2	2.0	0.7	1.5	1.5
Extinction: sum of active levers before priming	0.5	0.7	1.6	0.9	-0.2	0.6	0.5	0.6	0.6	-0.9	-1.1	-1.0	-1.3
Active lever presses in extinction session 6	0.5	0.5	1.2	0.9	0.2	0.3	0.3	0.4	0.4	-0.6	-0.8	-0.9	-1.1
Bone: final force	0.6	0.9	2.0	0.8	-0.0	0.6	0.6	0.9	0.9	-0.8	-1.3	-1.3	-1.4
Bone: final moment	0.7	1.1	2.4	1.1	0.1	0.6	0.5	0.9	0.9	-0.8	-1.5	-1.4	-1.5
Food consumed during 24 hour testing period	0.4	0.9	2.5	1.6	1.2	-0.6	-0.6	-0.6	-0.6	0.4	-1.6	-0.5	-0.5
Glucose	1.3	2.0	3.0	-1.7	-1.7	1.7	1.7	1.6	1.6	-1.3	-0.3	-1.1	-0.8
Heart weight	0.7	1.2	4.7	2.2	1.2	-0.1	-0.3	-0.3	-0.3	-0.1	-1.6	-1.0	-1.3
Delay discount hyperbolic model param	2.9	3.7	5.5	1.5	2.2	-2.3	-2.2	-2.2	-2.2	2.0	0.8	1.5	1.5
Intermittent access intake day 1-15 change	0.1	0.4	2.2	-0.7	0.0	-0.2	-0.5	-0.3	-0.3	0.5	1.5	0.7	0.8
Intermittent access intake escalation	0.1	0.5	2.3	-0.8	-0.0	-0.3	-0.5	-0.3	-0.3	0.5	1.5	0.8	0.9
Intermittent access intake escalation 2	0.3	0.5	1.9	-1.4	-0.9	0.7	0.3	0.6	0.6	-0.4	0.9	-0.0	0.2
Intermitt. access day 1 inactive lever presses	0.0	0.5	1.2	0.4	-0.1	0.6	0.6	0.6	0.6	-0.6	-1.1	-1.0	-1.1
Intermitt. access day 15 inactive lever presses	0.2	1.3	2.6	0.2	-0.7	1.1	1.2	1.1	1.1	-1.1	-1.6	-1.3	-1.3
Intermitt. access escalation Index	0.1	0.4	0.9	-0.8	-1.0	0.7	0.6	0.7	0.7	-0.5	0.1	0.0	0.0
Intermittent access day 1 total infusions	0.4	1.1	1.9	1.3	1.2	-1.4	-1.2	-1.1	-1.1	1.0	-0.2	0.6	0.6
Intermittent access day 15 total infusions	0.5	1.3	1.9	0.1	0.7	-1.3	-1.2	-1.0	-1.0	1.3	1.3	1.3	1.4
Intermittent access terminal intake (last 3 days)	0.4	0.7	1.1	0.4	0.8	-1.1	-1.0	-0.8	-0.8	1.0	0.7	0.8	0.9
Intermittent access total infusions	0.9	1.0	1.7	0.8	1.1	-1.3	-1.2	-1.0	-1.0	1.2	0.6	0.9	1.0
Intermittent access day 1 locomotion	0.1	0.1	0.3	0.1	0.2	-0.4	-0.3	-0.3	-0.3	0.5	0.5	0.5	0.5
Intermittent access day 15 total locomotion	0.7	2.6	3.8	1.3	1.8	-1.9	-1.9	-1.8	-1.8	1.7	1.1	1.4	1.3
Intermittent access total locomotion	1.8	2.2	3.1	1.5	1.8	-1.8	-1.7	-1.5	-1.5	1.6	0.8	1.1	1.0
Intermittent access standard deviation	0.0	0.1	0.2	0.4	0.3	0.1	0.1	0.1	0.1	-0.0	-0.2	-0.5	-0.4
Left kidney weight	3.4	27.3	77.7	8.8	7.7	-5.2	-5.4	-5.2	-5.2	4.3	-2.5	0.9	-0.0
Right kidney weight	3.4	23.5	82.1	9.1	7.1	-4.3	-4.4	-4.3	-4.3	3.2	-3.9	-0.5	-1.4
Cocaine induced anxiety	0.3	0.9	2.1	1.5	0.3	0.5	0.5	0.5	0.5	-0.8	-1.1	-1.3	-1.4
Post-drug Anxiety	1.6	1.9	2.6	-0.0	-1.0	1.5	1.6	1.5	1.5	-1.6	-0.9	-1.6	-1.6
Baseline Anxiety	0.5	0.8	4.1	-2.0	-1.2	0.6	0.6	0.6	0.6	-0.2	0.8	0.6	0.7
Tail length	0.2	0.8	2.1	-1.4	-0.7	-0.1	-0.2	-0.2	-0.2	0.6	1.2	1.3	1.4
Length with tail	0.2	1.1	1.6	0.8	1.0	-1.1	-1.2	-1.3	-1.3	1.2	0.2	0.9	0.9
Length without tail	0.3	1.5	5.3	2.3	1.2	-0.3	-0.4	-0.5	-0.5	-0.2	-2.2	-1.1	-1.3
Times rat made contact with spout	0.3	0.3	1.0	0.7	0.1	0.4	0.4	0.4	0.4	-0.4	-1.0	-0.8	-0.8
Lifetime Intake	1.1	1.3	2.2	1.0	1.3	-1.5	-1.3	-1.2	-1.2	1.3	0.5	0.9	0.9
Liver weight, left	0.2	0.4	1.3	1.1	0.9	-0.5	-0.4	-0.5	-0.5	0.6	0.1	0.1	-0.0
Liver weight, right	0.1	0.2	0.6	0.8	0.7	-0.5	-0.4	-0.5	-0.5	0.7	0.1	0.2	0.3
Locomotor activity	0.9	1.4	2.7	1.3	1.7	-1.5	-1.4	-1.3	-1.3	1.2	-0.1	0.6	0.5
Locomotor testing distance	0.0	0.1	0.4	-0.6	-0.1	-0.1	-0.1	0.1	0.1	0.1	0.3	0.2	0.3
Locomotor testing rearing	0.1	0.3	0.7	0.2	0.7	-0.7	-0.7	-0.4	-0.4	0.8	0.0	0.5	0.5
Locomotion in novel chamber	2.3	3.1	6.0	-0.8	0.6	-1.5	-1.5	-1.6	-1.6	1.8	2.5	2.3	2.3
Locomotion in novel chamber post-restriction	0.0	0.1	1.0	-0.2	0.0	-0.1	-0.2	-0.1	-0.1	0.0	1.0	0.2	0.2
Fecal boli incidents, locomotor time 1	0.2	0.6	1.7	1.3	1.1	-0.8	-0.8	-0.9	-0.9	0.5	-0.3	0.2	0.1
Change in fecal boli incidents, locomotor task	1.0	1.1	1.8	-0.1	0.6	-1.1	-1.1	-1.0	-1.0	1.1	1.2	1.3	1.3
Time >=10cm from walls, locomotor time 1	0.1	0.2	0.7	0.8	0.6	-0.1	-0.1	-0.2	-0.2	-0.0	-0.2	-0.4	-0.4
Bouts of movement, locomotor time 1	0.6	0.8	1.6	0.4	-0.3	0.9	0.9	0.8	0.8	-1.0	-0.8	-1.2	-1.3
Total resting periods, locomotor time 1	1.7	1.9	3.2	0.0	-0.8	1.5	1.5	1.4	1.4	-1.6	-1.1	-1.7	-1.8
Rest time, locomotor task time 1	0.2	0.3	1.4	1.2	0.8	-0.3	-0.3	-0.2	-0.2	0.0	-0.4	-0.5	-0.7
Distance moved, locomotor task time 1	0.0	0.0	0.0	-0.1	0.1	-0.0	-0.0	-0.1	-0.1	0.1	-0.0	0.0	0.1
Vertical activity count, locomotor time 1	0.0	0.3	0.7	-0.9	-0.7	0.6	0.6	0.5	0.5	-0.5	-0.2	-0.3	-0.2
Time >=10cm from walls, locomotor time 2	0.1	0.2	1.1	-0.4	-0.0	-0.2	-0.2	-0.3	-0.3	0.2	1.1	0.4	0.5
Bouts of movement, locomotor time 2	0.9	2.8	3.9	-0.2	-1.2	1.9	1.9	1.9	1.9	-1.9	-1.0	-2.0	-2.0
Total resting periods, locomotor time 2	0.8	3.3	4.7	-0.1	-1.3	2.0	2.0	2.0	2.0	-2.1	-1.2	-2.2	-2.2
Rest time, locomotor task time 2	0.2	0.4	0.8	-0.5	-0.9	0.7	0.7	0.7	0.7	-0.7	-0.0	-0.3	-0.4
Distance moved, locomotor task time 2	1.9	2.6	3.7	1.1	1.9	-1.9	-1.9	-1.9	-1.9	1.8	0.6	1.2	1.2
Vertical activity count, locomotor time 2	1.0	2.2	3.1	0.8	1.7	-1.7	-1.7	-1.8	-1.8	1.7	0.8	1.2	1.2
Light reinforcement 1	1.1	4.9	6.8	1.2	2.2	-2.6	-2.3	-2.6	-2.6	2.5	1.4	2.2	2.1
Light reinforcement 2	1.4	3.1	4.6	1.6	2.1	-2.0	-1.9	-2.0	-2.0	1.9	1.4	1.3	1.2
Bone: marrow area	2.4	6.0	10.2	2.9	3.2	-2.8	-2.8	-2.7	-2.7	2.4	0.8	1.6	1.3
Bone: maximum diameter	3.2	6.5	12.0	3.2	3.5	-2.9	-2.9	-2.8	-2.8	2.5	0.6	1.4	1.1
Bone: maximum force	0.3	0.6	1.9	1.4	0.7	-0.0	-0.1	0.2	0.2	-0.3	-1.2	-0.9	-1.1
Bone: maximum moment	0.4	0.8	2.8	1.7	0.8	-0.1	-0.2	0.1	0.1	-0.3	-1.5	-1.1	-1.2
Mean time between licks in bursts	0.2	1.0	4.6	-2.1	-1.3	0.5	0.5	0.5	0.5	-0.2	1.5	0.5	0.8
Mean num. licks in bursts	0.4	1.2	3.3	1.6	0.3	0.4	0.4	0.4	0.4	-0.7	-1.8	-1.5	-1.6
Cd content in liver	0.2	0.2	0.4	0.4	0.6	-0.5	-0.5	-0.6	-0.6	0.5	0.0	0.3	0.4
Co content in liver	0.1	0.1	0.3	-0.1	0.2	-0.3	-0.3	-0.4	-0.4	0.4	0.3	0.5	0.5
Cu content in liver	1.1	1.4	4.5	-2.1	-1.6	0.3	0.4	0.5	0.5	-0.6	2.1	0.8	0.8
Fe content in liver	0.1	0.1	0.2	0.5	0.5	-0.3	-0.2	-0.3	-0.3	0.1	-0.5	0.0	-0.1
K content in liver	0.3	0.3	0.5	0.5	0.4	-0.7	-0.7	-0.7	-0.7	0.4	-0.1	0.4	0.3
Mg content in liver	0.1	0.1	0.2	-0.1	-0.3	0.1	0.1	0.2	0.2	-0.4	-0.3	-0.3	-0.3
Mn content in liver	0.7	0.8	1.2	0.7	0.9	-1.0	-0.9	-1.1	-1.1	1.1	0.2	0.8	0.8
Na content in liver	0.2	0.2	0.9	-1.0	-0.7	0.1	0.1	0.2	0.2	-0.4	0.4	0.1	0.2
Rb content in liver	0.7	0.8	1.3	-0.3	-0.8	0.9	0.9	0.9	0.9	-1.2	-0.9	-0.9	-1.0
Se content in liver	0.2	0.2	0.6	-0.4	0.0	-0.3	-0.3	-0.5	-0.5	0.4	0.6	0.7	0.8
Sr content in liver	0.3	0.3	0.5	-0.7	-0.7	0.6	0.6	0.7	0.7	-0.4	0.1	-0.3	-0.1
Zn content in liver	0.3	0.3	0.6	0.4	0.6	-0.8	-0.7	-0.6	-0.6	0.6	0.1	0.5	0.4
Bone: minimum diameter	2.7	5.2	6.7	1.0	2.3	-2.6	-2.6	-2.4	-2.4	2.5	2.2	2.2	2.2
Time in familiar zone, hab. session 1	0.6	0.7	1.2	0.7	1.1	-0.9	-1.0	-1.0	-1.0	0.8	0.0	0.6	0.5
Time in novel zone, hab. session 1	0.1	0.2	0.3	-0.5	-0.5	0.4	0.4	0.5	0.5	-0.3	0.1	-0.1	0.0
Total zone transitions, hab. session 1	0.9	1.2	2.4	-1.5	-1.5	1.3	1.2	1.3	1.3	-1.0	-0.1	-0.4	-0.3
Total locomotion distance, hab. session 1	0.4	0.5	0.8	0.4	0.7	-0.7	-0.7	-0.7	-0.7	0.9	0.6	0.9	0.8
Locomotion velocity, hab. session 1	0.4	0.5	0.8	0.5	0.7	-0.8	-0.8	-0.6	-0.6	0.9	0.5	0.8	0.8
Time in familiar zone, hab. session 2	0.2	0.2	0.6	-0.4	-0.0	-0.5	-0.5	-0.2	-0.2	0.6	0.4	0.8	0.8
Time in novel zone, hab. session 2	0.2	0.2	0.3	-0.1	-0.4	0.5	0.6	0.3	0.3	-0.6	-0.4	-0.5	-0.5
Total zone transitions, hab. session 2	0.2	0.3	1.9	0.6	0.3	-0.1	-0.1	-0.1	-0.1	-0.1	-1.4	-0.3	-0.4
Total locomotion distance, hab. session 2	0.4	0.5	0.8	0.8	0.9	-0.9	-0.9	-0.8	-0.8	0.7	-0.2	0.6	0.5
Locomotion velocity, hab. session 2	0.2	0.3	0.5	0.7	0.7	-0.7	-0.7	-0.6	-0.6	0.5	-0.3	0.4	0.3
Novel to familiar place preference ratio	0.1	0.1	0.4	0.3	0.3	-0.3	-0.3	-0.6	-0.6	0.3	-0.0	0.3	0.3
Novelty place preference	0.4	0.5	1.0	0.5	0.7	-0.7	-0.7	-1.0	-1.0	0.8	0.1	0.6	0.6
Time in novel zone, NPP test	0.5	0.6	1.0	0.5	0.7	-0.8	-0.8	-1.0	-1.0	0.8	0.0	0.7	0.7
Total zone transitions, NPP test	0.1	0.1	0.5	-0.2	-0.5	0.2	0.2	0.2	0.2	-0.3	-0.7	-0.0	-0.0
Total locomotion distance, NPP test	0.8	1.1	1.5	0.8	1.0	-1.2	-1.2	-1.2	-1.2	1.1	0.4	1.2	1.0
Locomotion velocity, NPP test	0.6	0.8	1.1	0.5	0.7	-1.0	-0.9	-1.1	-1.1	1.0	0.7	1.0	1.0
Intraocular pressure	0.0	0.1	0.1	-0.2	0.2	-0.1	-0.1	-0.3	-0.3	0.4	0.3	0.3	0.4
Delta distance traveled before/after self-admin	1.7	1.8	2.7	0.8	1.5	-1.6	-1.6	-1.6	-1.6	1.4	0.4	1.3	1.1
Delta ambulatory time before/after self-admin	0.7	1.2	1.9	0.7	1.2	-1.3	-1.3	-1.4	-1.4	1.1	0.1	1.1	0.8
Parametrial fat weight	0.4	0.8	2.1	-1.4	-1.1	0.8	0.9	1.0	1.0	-0.3	1.2	0.2	0.3
Pavlov. Cond. lever latency	0.3	0.3	1.0	1.0	0.1	0.0	0.1	0.2	0.2	-0.5	-0.8	-0.7	-0.9
Pavlov. Cond. magazine entry latency	1.2	1.5	3.3	-1.8	-1.7	1.4	1.4	1.3	1.3	-1.2	-0.1	-0.6	-0.4
Pavlov. Cond. change in total contacts	1.3	1.3	3.0	-1.7	-1.5	1.4	1.3	1.1	1.1	-1.2	-0.0	-0.6	-0.5
Pavlov. Cond. index score	0.7	0.9	2.6	-1.6	-1.3	1.0	1.0	0.9	0.9	-0.8	0.0	-0.4	-0.1
Pavlov. Cond. latency score	0.3	0.3	1.8	-1.3	-0.8	0.5	0.5	0.4	0.4	-0.3	0.2	0.1	0.3
Pavlov. Cond. lever contacts	0.4	0.4	2.0	-1.4	-0.6	0.3	0.3	0.0	0.0	0.2	1.0	0.6	0.8
Pavlov. Cond. magazine entry number	1.6	2.0	3.5	1.9	1.9	-1.6	-1.6	-1.4	-1.4	1.5	0.1	0.8	0.6
Pavlov. Cond. intertrial magazine entries	0.2	0.2	0.6	-0.6	-0.8	0.5	0.4	0.5	0.5	-0.5	0.0	0.1	0.0
Pavlov. Cond. lever-magazine prob. diff.	0.8	1.0	3.1	-1.8	-1.4	1.1	1.1	0.9	0.9	-0.8	0.1	-0.3	-0.1
Pavlov. Cond. response bias	1.1	1.3	3.7	-1.9	-1.6	1.3	1.3	1.1	1.1	-1.0	0.4	-0.4	-0.2
Pavlov. Cond. lever latency	0.3	0.4	1.2	-1.1	-0.9	0.7	0.7	0.5	0.5	-0.3	0.5	0.1	0.2
Pavlov. Cond. magazine entry latency	0.6	0.9	1.5	-0.1	-0.8	1.0	0.9	0.9	0.9	-1.2	-1.0	-1.0	-1.1
Pavlov. Cond. change in total contacts	0.3	0.6	2.2	0.9	0.3	0.2	0.2	0.3	0.3	-0.7	-1.5	-1.0	-1.2
Pavlov. Cond. index score	0.2	0.3	0.6	0.5	0.1	0.3	0.2	0.3	0.3	-0.6	-0.8	-0.7	-0.8
Pavlov. Cond. latency score	0.1	0.2	0.6	0.6	0.2	0.2	0.1	0.2	0.2	-0.5	-0.7	-0.7	-0.7
Pavlov. Cond. lever contacts	0.2	0.3	0.9	1.0	0.6	-0.3	-0.4	-0.1	-0.1	-0.1	-0.8	-0.4	-0.5
Pavlov. Cond. magazine entry number	0.2	0.2	0.7	-0.5	-0.1	-0.3	-0.2	-0.2	-0.2	0.5	0.8	0.6	0.7
Pavlov. Cond. intertrial magazine entries	0.3	0.7	1.7	0.8	-0.0	0.6	0.6	0.7	0.7	-0.8	-1.1	-1.3	-1.3
Pavlov. Cond. lever-magazine prob. diff.	0.1	0.2	0.4	0.6	0.2	0.1	0.1	0.1	0.1	-0.4	-0.6	-0.5	-0.6
Pavlov. Cond. response bias	0.3	0.4	1.2	0.5	-0.0	0.3	0.3	0.4	0.4	-0.7	-1.1	-0.8	-0.9
Time in closed arm before self-admin	0.6	1.0	3.7	-1.9	-1.4	0.5	0.8	0.5	0.5	-0.4	1.6	0.5	0.7
Time in closed arm after self-admin	0.8	0.9	4.1	-2.0	-1.3	0.8	0.8	0.8	0.8	-0.4	0.6	0.1	0.3
Time in open arm before self-admin	0.1	0.2	0.4	0.5	0.6	-0.5	-0.4	-0.5	-0.5	0.3	-0.0	-0.1	-0.0
Time in open arm after self-admin	3.2	3.6	5.0	1.8	2.2	-2.2	-2.2	-2.2	-2.2	1.9	0.6	1.5	1.3
Bone: periosteal estimation	1.8	4.3	7.4	2.5	2.7	-2.4	-2.4	-2.3	-2.3	2.1	0.8	1.3	1.1
Bone: periosteal perimeter	3.4	6.6	9.0	1.9	3.0	-2.9	-3.0	-2.8	-2.8	2.8	1.8	2.2	2.0
Bone: post-yield work	2.2	3.8	5.1	-0.3	-1.5	2.0	2.0	2.0	2.0	-2.2	-2.1	-2.3	-2.3
Progressive ratio test 1 active lever presses	0.0	0.0	0.0	0.2	-0.1	-0.1	0.0	0.1	0.1	-0.0	-0.0	-0.0	0.0
Progressive ratio test 1 breakpoint	0.0	0.0	0.1	-0.0	-0.3	0.1	0.2	0.3	0.3	-0.2	0.0	-0.1	-0.0
Progressive ratio test 1 inactive lever presses	0.0	0.1	0.2	0.4	0.3	-0.0	0.2	0.2	0.2	0.2	-0.4	-0.1	-0.2
Progressive ratio test 2 active lever presses	0.4	0.5	2.4	1.5	0.6	-0.2	-0.2	-0.1	-0.1	-0.2	-1.1	-0.6	-0.7
Progressive ratio test 2 breakpoint	0.3	0.4	2.0	1.4	0.6	-0.3	-0.3	-0.1	-0.1	-0.1	-1.0	-0.5	-0.6
Progressive ratio test 2 inactive lever presses	0.0	0.1	0.6	0.8	0.4	-0.3	-0.4	-0.3	-0.3	0.2	-0.5	-0.1	-0.1
Incentive Sensitization - Responses	0.3	0.8	3.1	1.7	0.4	0.0	0.0	0.1	0.1	-0.4	-1.7	-0.9	-1.1
Incentive Sensitization - Breakpoint	0.4	0.9	3.2	1.8	0.5	0.0	-0.0	0.1	0.1	-0.4	-1.8	-0.9	-1.1
Sum of active levers in priming session hrs 5-6	0.2	0.1	0.5	0.7	0.6	-0.4	-0.4	-0.3	-0.3	0.3	-0.0	0.1	-0.1
Progressive ratio	0.3	1.0	1.5	-0.4	-1.0	1.2	1.2	0.9	0.9	-1.2	-0.7	-1.1	-1.0
Food seeking constrained by brief footshock	0.0	0.1	0.2	0.4	0.5	-0.0	-0.1	-0.1	-0.1	0.1	-0.3	-0.1	-0.3
Seeking ratio, punishment vs. effort	0.1	0.2	0.6	0.7	0.8	-0.6	-0.6	-0.2	-0.2	0.4	-0.1	0.2	-0.0
Retroperitoneal fat weight	0.6	2.7	11.2	3.3	2.5	-1.2	-1.2	-1.1	-1.1	0.7	-1.4	-0.7	-1.0
Reaction time number correct	0.1	0.5	1.4	-0.1	0.3	-0.8	-0.7	-0.7	-0.7	0.5	1.2	0.7	0.9
Reaction time mean minus median	0.0	0.2	0.3	0.0	0.2	-0.6	-0.6	-0.5	-0.5	0.2	-0.3	0.4	0.4
Reaction time mean minus median AUC	0.1	0.9	1.4	1.1	1.1	-1.2	-1.2	-1.2	-1.2	0.8	-0.3	0.5	0.5
Reaction time num false alarms	0.3	0.5	1.2	-0.5	0.2	-0.5	-0.4	-0.5	-0.5	0.7	0.9	0.9	1.1
Reaction time num false alarms AUC	0.2	0.5	1.2	-0.2	0.4	-0.6	-0.5	-0.7	-0.7	0.8	0.6	0.9	1.1
Reaction time trials correct on left	0.1	0.5	1.4	-0.1	0.3	-0.8	-0.7	-0.7	-0.7	0.5	1.2	0.7	0.9
Reaction time trials on left	0.1	0.5	1.3	-0.1	0.3	-0.7	-0.7	-0.7	-0.7	0.5	1.2	0.7	0.9
Reaction time mean	0.4	0.9	1.4	-0.7	-1.1	1.0	1.1	1.0	1.0	-1.2	-0.7	-0.8	-0.8
Reaction time mean AUC	0.3	0.8	1.3	-0.6	-1.1	1.0	1.0	0.9	0.9	-1.1	-0.7	-0.8	-0.8
Median of all reaction times	1.2	1.9	2.8	-0.9	-1.5	1.6	1.6	1.4	1.4	-1.7	-0.8	-1.2	-1.2
Reaction time omissions	0.3	0.5	0.9	-0.7	-0.9	0.7	0.8	0.7	0.7	-0.8	-0.6	-0.5	-0.4
Reaction time false alarm rate	0.0	0.1	0.2	-0.3	0.1	-0.0	0.0	-0.1	-0.1	0.4	0.0	0.4	0.5
Reaction time premature initiation rate	1.0	1.6	5.2	1.6	0.1	0.4	0.5	0.6	0.6	-1.1	-2.3	-1.7	-1.8
Reaction time premature initiations	0.3	0.8	2.2	1.3	0.2	0.1	0.2	0.2	0.2	-0.7	-1.5	-1.2	-1.2
Std. dev. reaction times	0.0	0.0	0.2	-0.1	-0.3	-0.0	0.0	0.1	0.1	-0.3	-0.4	-0.1	-0.1
Reaction time trials completed	0.1	0.5	1.3	-0.1	0.3	-0.7	-0.7	-0.7	-0.7	0.5	1.2	0.7	0.9
Reaction time trials AUC	0.1	0.5	1.1	0.1	0.5	-0.8	-0.8	-0.8	-0.8	0.6	1.1	0.7	0.8
Run reversals in cocaine runway, females	0.9	1.0	3.3	-1.8	-0.9	0.3	0.3	0.2	0.2	0.2	1.8	1.0	1.1
Run reversals in cocaine runway, males	1.7	1.9	2.9	1.1	1.6	-1.4	-1.5	-1.7	-1.7	1.5	0.5	1.2	1.2
Latency to leave start box in cocaine runway	0.3	0.4	0.9	0.7	0.9	-0.6	-0.6	-0.6	-0.6	0.7	-0.4	0.2	0.2
Latency to leave start box in cocaine runway, F	0.1	0.1	0.3	0.5	0.5	-0.2	-0.2	-0.1	-0.1	0.2	-0.5	-0.2	-0.2
Latency to leave start box in cocaine runway, M	0.6	0.6	1.0	0.5	0.9	-0.8	-0.7	-1.0	-1.0	1.0	0.2	0.7	0.7
Std. dev. time between licks in bursts	0.0	0.0	0.2	0.0	-0.2	-0.0	-0.0	0.0	0.0	-0.4	0.1	-0.2	-0.2
Total sessions with >9 infusions	1.7	2.1	4.0	1.9	2.0	-1.7	-1.6	-1.5	-1.5	1.4	-0.5	0.6	0.5
Short access day 1 total inactive lever presses	0.5	1.1	3.2	1.8	1.3	-0.9	-0.7	-0.9	-0.9	0.4	-1.6	-0.1	-0.4
Short access day 10 total inactive lever presses	0.1	0.5	1.2	1.1	1.1	-0.6	-0.7	-0.6	-0.6	0.6	-0.7	0.1	-0.1
Short access day 1 total infusions	0.2	0.5	0.9	0.8	1.0	-0.8	-0.8	-0.7	-0.7	0.7	-0.4	0.3	0.3
Short access day 10 total infusions	0.1	0.2	0.4	0.6	0.7	-0.7	-0.5	-0.3	-0.3	0.5	0.3	0.1	0.2
Short access total infusions	0.6	0.9	2.0	1.4	1.4	-1.2	-1.0	-0.9	-0.9	0.9	-0.4	0.3	0.2
Short access day 1 locomotion	0.0	0.0	0.1	0.3	0.3	-0.2	-0.2	0.0	0.0	0.3	-0.0	0.1	-0.0
Short access day 10 total locomotion	0.0	0.2	0.6	-0.7	-0.3	0.2	0.3	0.3	0.3	0.2	0.7	0.2	0.4
Short access total locomotion	0.1	0.1	0.3	-0.1	0.3	-0.4	-0.3	-0.2	-0.2	0.5	0.5	0.4	0.4
One hour access (0.3 mA shock)	1.3	1.5	2.3	1.0	1.3	-1.5	-1.4	-1.4	-1.4	1.3	1.0	0.8	1.0
Compulsive drug intake	0.4	0.5	2.7	1.0	0.4	-0.1	0.0	-0.2	-0.2	-0.4	-1.6	-0.8	-0.8
One hour access (shock baseline)	0.6	1.5	4.1	0.2	0.8	-1.2	-1.1	-1.1	-1.1	1.3	2.0	1.3	1.4
Social response proportion	0.2	0.3	0.6	0.6	0.8	-0.5	-0.5	-0.7	-0.7	0.7	-0.0	0.3	0.3
Social responses	1.3	1.7	2.4	0.9	1.4	-1.5	-1.5	-1.5	-1.5	1.5	0.5	1.0	1.2
Social time	1.5	2.3	4.2	-1.9	-2.1	1.9	1.9	1.6	1.6	-1.4	-0.5	-0.9	-0.6
Soleus weight	0.5	1.5	3.3	1.0	-0.1	1.0	0.9	1.0	1.0	-1.2	-1.8	-1.7	-1.8
Bone: stiffness	0.7	1.2	1.9	-0.3	-0.7	1.0	0.9	1.4	1.4	-1.2	-0.9	-1.4	-1.4
Tibialis anterior weight	0.0	0.0	0.1	-0.1	-0.1	0.1	-0.0	0.2	0.2	-0.3	-0.0	-0.1	-0.2
Time to tail flick, vehicle, before self-admin	0.3	0.3	0.5	0.6	-0.3	0.5	0.5	0.5	0.5	-0.6	-0.7	-0.7	-0.7
Time to tail flick, vehicle, after self-admin	0.0	0.1	0.3	0.3	0.2	-0.3	-0.2	-0.3	-0.3	0.1	0.5	0.3	0.3
Time to tail flick, test, before self-admin	0.1	0.1	0.4	-0.1	0.3	-0.1	-0.1	-0.1	-0.1	0.4	0.6	0.1	0.2
Time to tail flick, test, after self-admin	0.3	0.3	1.0	-1.0	-0.8	0.6	0.5	0.6	0.6	-0.5	-0.1	-0.2	-0.1
Delta time to tail flick, vehicle, before/after SA	0.3	0.4	1.3	1.2	0.8	-0.3	-0.2	-0.4	-0.4	0.0	-0.8	-0.4	-0.5
Delta time to tail flick, test, before/after SA	0.2	0.3	0.7	-0.8	-0.8	0.4	0.4	0.4	0.4	-0.6	-0.3	0.0	-0.0
Tibia length	0.1	0.2	0.4	0.6	0.4	-0.4	-0.5	-0.6	-0.6	0.3	-0.4	0.2	0.1
Ambulatory time before self-admin	0.1	0.2	0.5	-0.5	0.0	-0.5	-0.2	-0.4	-0.4	0.5	0.0	0.5	0.7
Ambulatory time after self-admin	0.5	0.7	1.5	-0.7	0.2	-1.0	-0.7	-0.9	-0.9	0.8	0.5	1.2	1.2
Bone: tissue strength	0.3	0.3	0.6	0.2	-0.4	0.5	0.4	0.6	0.6	-0.7	-0.8	-0.6	-0.7
Total heroin consumption	0.6	0.7	3.2	1.8	1.0	-0.5	-0.5	-0.3	-0.3	-0.1	-0.9	-0.7	-0.9
Bone: trabecular number	0.5	0.9	3.6	-1.9	-1.3	0.6	0.5	0.8	0.8	-0.4	1.0	0.3	0.4
Bone: trabecular spacing	1.7	2.5	6.6	2.6	2.4	-1.6	-1.5	-1.8	-1.8	1.2	-0.7	0.1	-0.1
Bone: trabecular thickness	0.1	0.2	0.5	-0.7	-0.6	0.4	0.3	0.4	0.4	-0.1	0.5	0.2	0.2
Bone: trabecular tissue density	0.3	0.5	0.8	-0.2	-0.6	0.9	0.9	0.7	0.7	-0.8	-0.7	-0.7	-0.7
Water consumed over 24 hours	0.3	0.6	1.5	1.2	1.0	-0.7	-0.7	-0.7	-0.7	0.5	-1.1	-0.0	-0.1
Number of responses in last shaping day	1.0	1.3	2.3	-0.9	-1.2	1.3	1.2	1.5	1.5	-1.2	-0.4	-1.0	-0.9