Hub : Genes

Kctd20

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Kctd20 0.12 0.08 1.3e-12 0.13 0.12 0.1 0.13 2.5e-12 6.3e-11 1.3e-09 4.7e-12
2 OFC gene expression Kctd20 0.28 0.2 1.6e-05 0.17 0.22 0.18 0.18 7.1e-05 5.6e-06 5.0e-05 5.8e-05
3 NAcc mRNA stability Kctd20 0.06 0.05 1.3e-05 0.02 0.04 0.03 0.03 9.0e-04 2.8e-05 1.6e-04 5.1e-04
4 BLA gene expression Kctd20 0.12 0.07 4.5e-07 0.13 0.12 0.11 0.11 1.8e-07 3.6e-07 1.6e-06 1.1e-06
5 Brain isoform ratio XM_017601866.2 0.03 0.02 2.4e-03 0.01 0.01 0.01 0.01 4.1e-02 1.2e-02 5.9e-02 8.5e-02
6 PL gene expression Kctd20 0.11 0.06 1.2e-14 0.11 0.14 0.13 0.13 8.1e-12 1.1e-14 8.4e-14 5.8e-14
7 Adipose isoform ratio XM_039099246.1 0.02 0.02 7.1e-03 0 0.01 0 0 1.3e-01 4.3e-02 1.5e-01 2.6e-01
8 Adipose mRNA stability Kctd20 0.04 0.03 2.7e-06 0.04 0.04 0.03 0.04 9.9e-06 9.4e-06 1.3e-04 6.2e-05
9 pVTA gene expression Kctd20 0.12 0.1 1.7e-03 0.04 0.05 0.03 0.04 5.3e-03 3.0e-03 1.6e-02 9.2e-03
10 IL gene expression Kctd20 0.14 0.11 4.7e-03 0.05 0.05 0.02 0.04 2.0e-02 2.4e-02 8.7e-02 4.0e-02
11 NAcc gene expression Kctd20 0.12 0.11 1.7e-10 0.1 0.09 0.09 0.09 3.2e-11 1.2e-10 4.7e-11 5.6e-11
12 PL mRNA stability Kctd20 0.15 0.11 7.8e-11 0.08 0.09 0.09 0.09 1.9e-09 2.4e-10 6.7e-10 2.8e-10
13 pVTA intron excision ratio chr20_7015975_7024431 0.06 0.06 5.3e-03 0.03 0.03 -0 0.02 1.6e-02 1.6e-02 4.6e-01 5.5e-02
14 Liver isoform ratio XM_006256152.4 0.42 0.18 1.3e-04 0.01 0.03 0.02 0.02 2.4e-02 2.5e-04 1.0e-03 2.1e-03
15 Adipose gene expression Kctd20 0.03 0.03 1.6e-03 0.04 0.02 0.03 0.02 4.8e-05 1.7e-03 5.9e-04 2.0e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.40.71.1-1.10.90.8-1.0-0.90.8-1.00.91.0-0.9-0.80.7-0.70.40.0
Area under the delay curve0.80.91.81.1-0.9-1.11.01.0-0.90.8-0.9-0.81.10.8-0.90.6-1.3-0.4
BMI with tail1.65.16.72.6-2.4-2.52.52.5-2.42.4-2.4-2.32.52.3-2.21.2-2.30.0
BMI without tail1.12.23.11.7-1.6-1.61.61.6-1.61.6-1.6-1.61.71.4-1.50.5-1.40.0
Body weight5.723.728.25.3-5.2-5.35.25.2-5.25.0-5.1-5.05.25.1-5.24.0-4.40.0
Weight adjusted by age1.01.12.10.9-1.0-1.20.91.0-1.10.9-1.0-0.90.91.0-1.31.4-1.50.2
Bone surface0.00.00.1-0.20.0-0.1-0.2-0.0-0.1-0.10.00.0-0.10.1-0.10.0-0.30.0
Bone volume0.00.00.2-0.0-0.2-0.2-0.00.2-0.20.1-0.1-0.10.10.2-0.30.2-0.40.0
Breakpoint value in progressive ratio session0.40.42.0-0.50.50.6-0.5-0.60.5-0.40.50.4-0.5-0.50.50.71.40.7
Number of licking bursts0.50.61.3-0.80.90.9-0.8-0.80.8-0.70.80.7-0.8-0.70.9-1.10.30.0
Context. condit. distance diff. score0.30.40.9-0.40.70.7-0.5-0.60.7-0.70.70.7-0.6-0.70.8-0.90.30.0
Locomotion velocity, session 10.60.61.3-0.80.90.7-0.8-0.80.8-1.00.90.9-0.7-0.80.6-1.1-0.40.0
Locomotion distance, session 13.24.15.0-2.22.12.1-2.1-2.12.1-2.22.12.2-2.2-2.12.1-2.21.10.0
Locomotion velocity, session 20.30.41.6-0.50.70.6-0.6-0.60.6-0.60.60.6-0.6-0.60.6-1.3-0.40.0
Locomotion distance, session 20.81.11.3-1.21.11.0-1.0-1.11.1-1.21.11.2-1.1-1.11.0-1.00.70.0
Locomotion velocity, session 30.50.61.20.7-0.7-0.70.70.8-0.80.8-0.8-0.80.70.9-0.80.3-1.10.0
Locomotion distance, session 30.30.31.1-0.50.50.5-0.4-0.50.5-0.50.50.5-0.5-0.50.6-1.1-0.20.0
Stereotopy head waving bouts, day 31.82.22.71.6-1.6-1.51.61.5-1.51.6-1.5-1.51.61.5-1.51.5-0.90.0
Stereotopy head waving duration, day 30.10.10.20.4-0.4-0.40.30.3-0.40.3-0.3-0.30.20.3-0.40.4-0.30.0
Locomotion velocity, session 70.00.00.2-0.10.0-0.1-0.1-0.1-0.0-0.20.10.2-0.1-0.1-0.20.0-0.40.0
Locomotion distance, session 70.60.81.3-0.91.00.8-0.9-1.00.9-1.11.01.1-0.9-1.00.7-0.80.30.0
Stereotopy head waving bouts, day 70.40.50.70.7-0.7-0.70.60.8-0.80.8-0.8-0.80.80.8-0.70.4-0.70.0
Stereotopy head waving duration, day 71.21.51.81.2-1.3-1.21.11.3-1.31.3-1.3-1.31.31.3-1.30.8-1.30.0
Locomotion velocity, session 80.00.00.00.00.00.00.1-0.00.1-0.10.10.1-0.2-0.10.1-0.1-0.00.0
Locomotion distance, session 80.81.21.5-1.11.11.1-1.1-1.11.2-1.11.21.2-1.2-1.21.2-1.10.90.0
Degree of sensitization distance0.00.00.3-0.00.0-0.1-0.0-0.10.0-0.20.10.2-0.0-0.1-0.10.60.40.0
Degree of sensitization stereotypy0.00.00.30.0-0.00.0-0.10.1-0.10.1-0.1-0.10.10.1-0.1-0.4-0.50.0
Conditioned locomotion2.63.13.71.9-1.9-1.81.91.8-1.91.9-1.9-1.91.81.8-1.81.9-0.90.0
Cocaine response after cond. corrected0.50.50.90.8-0.8-0.80.70.8-0.70.8-0.8-0.80.60.7-0.50.90.00.0
Cocaine response after cond. not corrected0.50.61.20.9-0.8-0.80.80.8-0.70.9-0.8-0.80.70.7-0.51.10.20.0
Cocaine response before conditioning0.00.00.10.2-0.1-0.10.20.1-0.10.1-0.1-0.10.30.0-0.20.30.10.0
Saline control response0.70.91.81.1-1.0-1.01.10.9-0.90.9-0.9-0.91.00.8-0.91.4-0.10.0
Bone: connectivity density0.40.61.1-1.00.80.7-1.0-0.80.7-0.90.80.9-0.9-0.70.5-0.7-0.00.0
Bone: cortical apparent density0.10.21.4-0.0-0.2-0.0-0.00.1-0.10.2-0.1-0.2-0.00.2-0.11.01.20.0
Bone: cortical area0.20.30.70.7-0.6-0.70.70.6-0.50.5-0.5-0.40.60.4-0.40.3-0.80.0
Bone: cortical porosity0.00.00.40.00.0-0.10.0-0.0-0.0-0.20.10.10.0-0.0-0.1-0.2-0.60.0
Bone: cortical porosity0.00.00.3-0.00.1-0.10.0-0.10.0-0.20.10.2-0.0-0.1-0.1-0.1-0.50.0
Bone: cortical thickness0.10.10.2-0.20.40.3-0.2-0.40.4-0.50.40.5-0.3-0.50.4-0.4-0.00.0
Bone: cortical thickness0.00.00.10.3-0.1-0.10.30.1-0.10.1-0.1-0.10.20.1-0.00.0-0.10.0
Bone: cortical tissue density0.10.21.20.0-0.3-0.10.00.2-0.20.3-0.2-0.30.10.3-0.21.01.10.0
Condit. Reinf. active minus inactive responses0.80.91.6-1.11.00.8-1.2-1.00.9-1.11.01.1-1.0-1.00.7-1.3-0.40.0
Condit. Reinf. active-inactive response ratio0.10.10.2-0.40.30.2-0.4-0.20.2-0.30.30.3-0.3-0.30.3-0.5-0.20.0
Condit. Reinf. active responses0.20.20.4-0.50.50.3-0.6-0.40.3-0.60.50.5-0.4-0.40.1-0.6-0.60.0
Condit. Reinf. inactive responses0.10.10.2-0.40.40.3-0.4-0.40.3-0.50.40.4-0.3-0.30.1-0.10.10.0
Incentive salience index mean0.30.41.0-0.70.60.5-0.8-0.60.5-0.70.60.7-0.6-0.60.4-1.0-0.70.0
Condit. Reinf. lever presses0.10.10.7-0.30.30.1-0.3-0.20.2-0.30.30.3-0.2-0.20.1-0.7-0.80.0
Condit. Reinf. active minus inactive responses0.60.81.2-1.00.90.9-1.1-0.90.9-0.90.90.9-0.9-0.80.8-0.60.70.0
Condit. Reinf. active-inactive response ratio0.30.30.7-0.80.50.6-0.8-0.60.5-0.50.50.5-0.5-0.40.4-0.10.70.0
Condit. Reinf. active responses0.60.81.0-1.00.90.9-1.0-0.90.9-1.00.91.0-0.9-0.90.9-0.90.50.0
Condit. Reinf. inactive responses0.00.00.10.3-0.2-0.30.30.3-0.20.2-0.2-0.20.30.1-0.10.0-0.30.0
Condit. Reinf. lever presses3.44.65.8-2.12.32.2-2.1-2.22.3-2.32.32.3-2.2-2.42.4-2.21.60.0
Condit. Reinf. lever reinforcers received1.21.72.3-1.41.41.3-1.4-1.41.4-1.41.41.4-1.3-1.41.4-1.50.70.0
Conditioned reinforcement - actives0.80.83.60.8-0.7-0.90.80.8-0.80.6-0.7-0.60.80.8-1.0-0.1-1.9-0.8
Conditioned reinforcement - inactives0.10.10.6-0.20.30.4-0.2-0.30.3-0.30.30.3-0.2-0.30.3-0.70.4-0.1
Conditioned locomotion0.70.93.30.9-0.8-1.10.90.8-0.90.6-0.8-0.60.90.8-1.10.8-1.8-0.6
Patch foraging indifference point 0 sec0.30.40.60.8-0.7-0.60.80.7-0.70.8-0.7-0.80.70.7-0.60.5-0.00.0
Patch foraging indifference point AUC0.00.00.2-0.10.20.2-0.1-0.10.2-0.10.10.1-0.2-0.10.3-0.50.00.0
Delay disc. indifference point, 0s delay0.00.10.40.2-0.2-0.30.10.2-0.20.1-0.2-0.10.20.1-0.1-0.1-0.6-0.1
Delay disc. indifference point, 16s delay0.30.31.20.5-0.4-0.50.40.5-0.40.3-0.4-0.30.50.4-0.5-0.2-1.0-1.1
Delay disc. indifference point, 2s delay0.10.10.6-0.20.30.2-0.3-0.40.3-0.50.40.5-0.2-0.50.30.20.1-0.8
Delay disc. indifference point, 24s delay2.42.34.51.6-1.6-1.71.51.6-1.61.4-1.5-1.41.61.5-1.61.0-2.1-0.2
Delay disc. indifference point, 4s delay1.01.11.41.2-1.1-1.11.11.1-1.11.1-1.1-1.11.20.9-1.01.1-0.90.6
Delay disc. indifference point, 8s delay1.81.93.11.6-1.4-1.51.51.4-1.41.2-1.3-1.21.61.3-1.41.3-1.80.1
Indifference point function ln k0.10.20.6-0.50.40.4-0.5-0.40.3-0.40.40.4-0.4-0.40.3-0.8-0.30.0
Indifference point function log k0.10.20.6-0.50.40.4-0.5-0.40.3-0.40.40.4-0.4-0.40.3-0.8-0.30.0
Patch foraging total patch changes 0 sec0.20.40.50.7-0.7-0.60.70.7-0.60.7-0.7-0.70.70.6-0.50.50.10.0
Patch foraging total patch changes 12 sec0.00.00.10.10.10.20.1-0.00.20.10.1-0.0-0.0-0.10.4-0.40.40.0
Patch foraging total patch changes 18 sec0.60.81.41.1-1.0-0.81.21.0-0.81.1-1.0-1.00.90.9-0.61.10.40.0
Patch foraging total patch changes 24 sec0.40.51.4-0.70.60.7-0.6-0.60.7-0.60.60.6-0.6-0.80.8-0.41.20.0
Patch foraging total patch changes 6 sec0.00.10.20.2-0.3-0.20.30.3-0.20.3-0.3-0.30.20.1-0.10.20.40.0
Patch foraging time to switch 0 sec0.91.52.91.2-1.3-1.31.41.3-1.31.3-1.3-1.31.21.1-1.11.7-0.40.0
Patch foraging water rate 0 sec0.20.30.6-0.60.60.6-0.7-0.60.6-0.50.60.5-0.6-0.40.6-0.50.80.0
Patch foraging water rate 12 sec0.20.20.5-0.60.50.5-0.6-0.40.5-0.40.40.4-0.4-0.40.5-0.70.50.0
Patch foraging water rate 18 sec0.50.61.7-0.90.70.8-1.0-0.80.8-0.70.80.7-0.7-0.80.7-0.11.30.0
Patch foraging water rate 24 sec0.40.61.5-0.60.70.8-0.8-0.70.8-0.50.70.6-0.6-0.81.0-0.81.20.0
Patch foraging water rate 6 sec0.20.20.6-0.30.50.6-0.5-0.50.5-0.40.50.4-0.3-0.50.6-0.80.40.0
Seeking ratio, delayed vs. immediate footshock0.10.10.70.1-0.10.10.20.1-0.00.3-0.2-0.30.10.20.00.10.90.5
Distance traveled before self-admin0.80.81.41.0-0.9-0.71.00.9-0.81.2-1.0-1.21.00.9-0.80.80.10.7
Distance traveled after self-admin0.30.41.40.3-0.3-0.10.30.3-0.30.6-0.4-0.60.30.4-0.31.01.21.2
Extensor digitorum longus weight0.20.60.8-0.70.90.9-0.8-0.90.9-0.90.90.9-0.9-0.90.8-0.70.70.0
Bone: elastic displacement0.00.00.1-0.20.20.1-0.2-0.20.1-0.30.20.3-0.2-0.20.0-0.1-0.20.0
Bone: elastic work0.00.00.10.2-0.1-0.20.20.1-0.1-0.0-0.00.00.1-0.0-0.10.1-0.30.0
Bone: endosteal estimation3.06.57.62.7-2.7-2.82.72.8-2.72.7-2.7-2.72.62.6-2.52.3-2.00.0
Bone: endosteal perimeter1.53.04.01.8-1.9-1.81.81.9-1.92.0-1.9-2.01.71.9-1.61.7-1.10.0
Epididymis fat weight1.32.93.61.9-1.8-1.91.91.8-1.81.7-1.8-1.71.91.8-1.81.1-1.50.0
Delta time in closed arm before/after self-admin1.41.41.61.3-1.2-1.21.31.2-1.21.2-1.2-1.21.31.3-1.20.8-1.01.0
Delta time in open arm before/after self-admin0.70.71.0-0.90.90.8-0.9-0.90.9-0.90.90.9-0.9-1.00.9-0.30.6-0.3
Diff in mean of infusions in LGA sessions0.91.03.1-1.11.01.0-1.1-1.01.0-0.91.01.0-1.1-1.01.00.01.80.1
Delay discount exponential model param0.70.71.6-1.00.81.0-0.9-0.90.8-0.70.80.7-1.0-0.70.8-0.51.30.5
Extinction: sum of active levers before priming0.20.20.3-0.40.50.5-0.4-0.50.5-0.40.50.4-0.4-0.60.4-0.30.5-0.3
Active lever presses in extinction session 60.20.21.3-0.0-0.2-0.3-0.00.1-0.1-0.0-0.10.0-0.00.1-0.11.10.30.9
Bone: final force3.86.27.42.7-2.7-2.72.72.7-2.62.6-2.6-2.62.52.6-2.52.5-1.80.0
Bone: final moment3.25.16.52.5-2.5-2.52.62.5-2.42.4-2.4-2.32.42.3-2.22.2-1.80.0
Food consumed during 24 hour testing period0.40.40.70.7-0.7-0.70.60.7-0.70.7-0.7-0.70.80.6-0.60.8-0.10.0
Glucose0.10.11.10.00.1-0.10.0-0.00.0-0.20.10.20.0-0.20.1-1.0-0.90.0
Heart weight2.23.24.1-1.92.01.8-1.9-1.91.9-2.01.92.0-1.9-1.81.7-2.00.80.0
Delay discount hyperbolic model param0.40.51.0-0.80.70.8-0.7-0.70.6-0.50.60.5-0.8-0.50.6-0.51.00.6
Intermittent access intake day 1-15 change0.90.91.21.0-1.0-1.01.01.0-1.01.0-1.0-1.01.01.1-1.10.6-0.80.7
Intermittent access intake escalation1.51.51.91.2-1.2-1.21.21.3-1.31.3-1.3-1.31.21.3-1.41.0-0.90.7
Intermittent access intake escalation 20.10.11.2-0.10.10.1-0.1-0.1-0.0-0.00.0-0.0-0.10.3-0.3-0.4-0.5-1.1
Intermitt. access day 1 inactive lever presses0.10.20.9-0.20.30.4-0.2-0.30.3-0.10.20.1-0.2-0.20.3-0.90.6-0.6
Intermitt. access day 15 inactive lever presses1.41.52.01.3-1.2-1.21.31.3-1.31.3-1.3-1.41.31.4-1.40.6-1.00.6
Intermitt. access escalation Index0.50.40.7-0.70.60.7-0.7-0.60.7-0.50.60.5-0.7-0.50.7-0.70.8-0.2
Intermittent access day 1 total infusions0.40.52.0-0.50.60.4-0.5-0.60.5-0.80.70.8-0.5-0.60.3-0.6-0.9-1.4
Intermittent access day 15 total infusions0.20.21.40.4-0.3-0.50.40.3-0.40.2-0.3-0.20.40.3-0.6-0.0-1.2-0.3
Intermittent access terminal intake (last 3 days)0.40.42.60.5-0.4-0.60.50.5-0.60.3-0.4-0.40.50.6-0.80.0-1.6-0.5
Intermittent access total infusions0.10.10.9-0.10.2-0.0-0.1-0.20.1-0.40.20.3-0.1-0.2-0.2-0.2-1.0-0.9
Intermittent access day 1 locomotion0.20.20.30.5-0.4-0.40.50.4-0.40.4-0.4-0.40.50.4-0.50.5-0.5-0.1
Intermittent access day 15 total locomotion5.25.66.92.5-2.4-2.42.52.4-2.42.4-2.4-2.52.52.4-2.62.5-1.81.4
Intermittent access total locomotion2.12.44.11.7-1.5-1.51.71.5-1.61.5-1.5-1.51.71.5-1.72.0-1.10.9
Intermittent access standard deviation0.91.01.31.0-1.0-1.01.01.0-1.01.0-1.0-1.11.01.1-1.00.9-0.41.1
Left kidney weight2.87.810.12.9-3.0-3.02.93.0-3.02.9-3.0-2.92.83.2-3.12.5-2.20.0
Right kidney weight3.610.211.93.4-3.4-3.43.33.4-3.43.3-3.4-3.33.33.5-3.52.9-2.60.0
Cocaine induced anxiety0.00.10.4-0.10.20.3-0.1-0.20.2-0.00.10.0-0.10.20.2-0.30.70.3
Post-drug Anxiety0.30.31.6-0.50.50.6-0.5-0.50.5-0.40.50.4-0.5-0.20.40.41.30.6
Baseline Anxiety0.30.40.7-0.60.50.5-0.6-0.60.5-0.60.60.6-0.6-0.70.60.60.80.4
Tail length1.13.44.82.0-2.0-2.01.91.9-2.01.9-2.0-2.02.11.9-2.21.3-1.60.0
Length with tail2.48.611.33.0-3.1-3.23.03.1-3.23.0-3.1-3.03.13.2-3.42.6-2.60.0
Length without tail1.73.85.31.9-2.1-2.12.02.0-2.12.0-2.0-2.01.92.2-2.12.3-1.50.0
Times rat made contact with spout2.42.83.4-1.81.81.8-1.8-1.81.8-1.81.81.8-1.7-1.71.7-1.61.30.0
Lifetime Intake0.20.21.60.3-0.2-0.40.30.2-0.30.0-0.2-0.00.30.2-0.50.2-1.3-0.7
Liver weight, left5.38.410.63.3-3.1-3.03.23.1-3.03.1-3.1-3.13.13.1-2.93.0-1.70.0
Liver weight, right2.44.05.22.3-2.1-2.02.32.1-2.12.3-2.2-2.32.12.2-2.01.6-1.20.0
Locomotor activity0.10.20.40.6-0.4-0.30.60.5-0.30.6-0.5-0.60.50.4-0.10.20.30.0
Locomotor testing distance0.00.00.10.20.00.20.20.00.10.1-0.0-0.10.2-0.10.4-0.30.40.0
Locomotor testing rearing0.91.32.01.4-1.2-1.11.41.2-1.11.4-1.3-1.31.41.1-1.01.1-0.10.0
Locomotion in novel chamber0.60.81.5-0.70.90.9-0.7-0.80.9-0.90.90.9-0.7-1.01.1-1.20.3-0.9
Locomotion in novel chamber post-restriction1.82.22.51.5-1.6-1.61.51.6-1.51.5-1.5-1.51.61.4-1.41.4-1.01.4
Fecal boli incidents, locomotor time 10.10.10.70.1-0.1-0.10.20.0-0.1-0.0-0.00.00.10.0-0.00.90.20.3
Change in fecal boli incidents, locomotor task0.10.10.20.3-0.2-0.20.20.3-0.20.3-0.2-0.30.30.2-0.00.2-0.30.4
Time >=10cm from walls, locomotor time 11.71.74.31.1-1.3-1.11.21.3-1.21.4-1.3-1.41.11.3-1.11.80.32.1
Bouts of movement, locomotor time 10.30.31.6-0.50.40.6-0.4-0.50.5-0.30.40.3-0.5-0.60.60.11.30.4
Total resting periods, locomotor time 10.10.10.7-0.10.10.2-0.1-0.20.2-0.00.10.1-0.1-0.30.20.40.80.3
Rest time, locomotor task time 10.20.21.20.3-0.3-0.40.20.3-0.30.3-0.3-0.30.30.4-0.4-0.4-1.1-0.7
Distance moved, locomotor task time 10.20.21.20.3-0.4-0.40.30.4-0.40.4-0.4-0.40.30.3-0.40.70.11.1
Vertical activity count, locomotor time 11.11.24.60.7-0.9-0.80.70.8-0.80.9-0.9-0.90.70.9-0.82.20.42.1
Time >=10cm from walls, locomotor time 25.45.76.72.4-2.4-2.62.42.4-2.52.3-2.4-2.32.42.4-2.42.3-2.32.2
Bouts of movement, locomotor time 20.20.20.90.3-0.4-0.30.40.4-0.30.6-0.5-0.50.30.3-0.31.00.80.1
Total resting periods, locomotor time 20.10.11.3-0.20.10.3-0.1-0.10.20.00.1-0.0-0.2-0.20.20.41.1-0.4
Rest time, locomotor task time 20.00.10.40.10.00.2-0.1-0.00.10.1-0.0-0.10.1-0.20.2-0.40.4-0.6
Distance moved, locomotor task time 22.63.03.91.6-1.7-1.81.61.7-1.81.5-1.6-1.61.61.7-1.91.9-1.92.0
Vertical activity count, locomotor time 21.81.95.01.1-1.3-1.51.11.2-1.41.1-1.2-1.11.11.5-1.62.2-1.11.6
Light reinforcement 11.83.34.52.0-1.9-1.82.12.0-1.92.1-2.0-2.12.11.9-1.71.6-0.90.0
Light reinforcement 22.23.03.81.8-1.9-1.81.91.9-1.82.0-1.9-1.91.81.8-1.61.6-0.90.0
Bone: marrow area3.16.77.92.8-2.8-2.82.82.8-2.82.7-2.8-2.72.72.7-2.62.4-2.10.0
Bone: maximum diameter0.30.50.70.8-0.8-0.80.80.8-0.80.7-0.8-0.70.70.7-0.60.6-0.70.0
Bone: maximum force1.42.53.31.6-1.7-1.81.71.7-1.71.6-1.6-1.61.51.6-1.61.4-1.60.0
Bone: maximum moment1.01.82.41.5-1.4-1.61.51.5-1.41.3-1.4-1.21.31.3-1.31.1-1.60.0
Mean time between licks in bursts0.50.71.2-1.10.91.0-1.1-0.90.9-0.80.80.7-0.9-0.80.9-1.10.60.0
Mean num. licks in bursts0.10.20.3-0.50.40.3-0.4-0.40.4-0.50.50.5-0.4-0.50.3-0.10.50.0
Cd content in liver1.21.31.81.1-1.2-1.31.01.2-1.21.0-1.1-1.01.21.2-1.41.2-1.20.0
Co content in liver2.02.42.81.5-1.6-1.61.61.7-1.71.7-1.7-1.71.61.6-1.61.1-1.60.0
Cu content in liver3.13.85.0-2.22.12.0-2.1-2.12.0-2.12.12.1-2.2-2.01.9-2.01.10.0
Fe content in liver4.14.96.12.1-2.4-2.42.12.3-2.42.3-2.4-2.32.22.4-2.52.3-1.90.0
K content in liver1.21.21.9-1.41.21.1-1.3-1.11.1-1.11.11.1-1.4-0.91.0-1.40.20.0
Mg content in liver2.82.85.9-1.81.81.7-1.8-1.71.7-1.81.81.8-1.8-1.61.7-2.40.00.0
Mn content in liver0.10.10.4-0.50.40.3-0.4-0.30.3-0.30.30.3-0.6-0.20.3-0.6-0.30.0
Na content in liver0.10.10.4-0.50.20.3-0.5-0.20.1-0.00.1-0.0-0.20.0-0.10.20.70.0
Rb content in liver0.10.20.80.5-0.3-0.50.50.4-0.40.2-0.3-0.20.50.3-0.40.1-0.90.0
Se content in liver2.73.35.1-2.12.01.9-2.1-1.91.9-1.91.91.9-2.0-1.71.7-2.30.60.0
Sr content in liver0.00.00.1-0.10.10.0-0.1-0.20.1-0.30.20.2-0.1-0.30.00.0-0.00.0
Zn content in liver0.50.61.51.2-0.8-0.91.20.8-0.70.6-0.7-0.50.90.4-0.40.2-1.10.0
Bone: minimum diameter0.91.82.41.5-1.5-1.51.51.5-1.41.4-1.4-1.41.31.3-1.21.2-1.10.0
Time in familiar zone, hab. session 10.00.00.10.10.10.00.0-0.10.1-0.20.10.2-0.0-0.10.1-0.3-0.30.0
Time in novel zone, hab. session 10.30.30.70.4-0.5-0.50.50.5-0.50.5-0.5-0.50.50.6-0.50.1-0.90.0
Total zone transitions, hab. session 12.33.35.1-1.92.02.0-1.9-2.01.9-1.91.91.9-1.9-1.81.8-2.30.70.0
Total locomotion distance, hab. session 11.72.43.8-1.61.71.7-1.6-1.71.7-1.61.71.6-1.6-1.61.6-1.90.80.0
Locomotion velocity, hab. session 11.62.33.4-1.51.71.7-1.5-1.61.6-1.61.61.6-1.6-1.51.5-1.80.80.0
Time in familiar zone, hab. session 21.51.66.7-1.01.11.4-1.1-1.11.3-0.91.11.0-1.2-1.21.5-0.42.60.0
Time in novel zone, hab. session 21.71.77.31.1-1.2-1.51.11.3-1.41.0-1.2-1.01.21.3-1.50.5-2.70.0
Total zone transitions, hab. session 20.40.51.2-0.80.70.9-0.7-0.70.8-0.50.60.5-0.8-0.70.9-0.61.10.0
Total locomotion distance, hab. session 22.43.24.5-1.81.82.0-1.8-1.81.9-1.61.71.6-1.9-1.82.1-1.72.10.0
Locomotion velocity, hab. session 22.83.85.3-2.02.02.2-2.0-2.02.1-1.81.91.8-2.1-2.02.3-1.82.30.0
Novel to familiar place preference ratio0.30.31.60.6-0.5-0.60.40.5-0.60.4-0.5-0.40.60.5-0.60.1-1.30.0
Novelty place preference0.30.31.30.6-0.4-0.60.40.5-0.50.4-0.4-0.40.60.5-0.60.1-1.10.0
Time in novel zone, NPP test0.30.31.40.6-0.5-0.70.40.6-0.60.4-0.5-0.40.70.6-0.60.2-1.20.0
Total zone transitions, NPP test1.62.22.8-1.61.61.6-1.5-1.51.6-1.61.61.6-1.6-1.61.6-1.70.90.0
Total locomotion distance, NPP test1.31.72.2-1.31.41.4-1.3-1.41.4-1.41.41.4-1.4-1.51.5-1.31.10.0
Locomotion velocity, NPP test1.92.83.4-1.71.81.8-1.6-1.71.8-1.71.81.7-1.7-1.81.8-1.61.50.0
Intraocular pressure1.01.42.01.2-1.4-1.41.21.4-1.31.3-1.3-1.31.21.2-1.10.6-1.10.0
Delta distance traveled before/after self-admin0.40.50.8-0.80.70.6-0.8-0.80.7-0.80.70.8-0.8-0.60.50.10.90.2
Delta ambulatory time before/after self-admin0.50.61.3-0.80.80.8-0.8-0.90.8-0.90.80.8-0.8-0.70.60.11.10.2
Parametrial fat weight1.93.85.32.2-2.1-1.92.12.1-2.02.3-2.2-2.32.22.0-1.81.7-1.10.0
Pavlov. Cond. lever latency0.60.82.90.8-0.8-0.60.80.7-0.60.9-0.8-0.90.70.6-0.51.71.40.0
Pavlov. Cond. magazine entry latency0.60.82.3-0.80.90.7-0.8-0.80.8-1.00.91.0-0.9-0.91.0-1.5-0.50.0
Pavlov. Cond. change in total contacts0.70.85.90.7-0.6-0.80.60.7-0.80.6-0.7-0.60.70.7-0.7-0.6-2.40.0
Pavlov. Cond. index score0.40.52.0-0.50.60.3-0.5-0.50.5-0.70.60.7-0.5-0.60.5-1.4-1.20.0
Pavlov. Cond. latency score0.30.41.7-0.40.50.3-0.4-0.40.4-0.60.50.6-0.4-0.50.5-1.3-1.20.0
Pavlov. Cond. lever contacts0.50.51.8-0.60.70.4-0.6-0.60.5-0.80.70.8-0.6-0.60.4-1.4-1.30.0
Pavlov. Cond. magazine entry number1.01.32.71.2-1.2-1.11.21.1-1.21.2-1.2-1.21.21.2-1.21.6-0.00.0
Pavlov. Cond. intertrial magazine entries0.00.00.2-0.10.0-0.1-0.1-0.1-0.1-0.10.00.10.00.1-0.40.4-0.10.0
Pavlov. Cond. lever-magazine prob. diff.0.40.52.3-0.40.50.3-0.4-0.40.4-0.70.50.7-0.4-0.50.4-1.5-1.50.0
Pavlov. Cond. response bias1.11.33.1-1.21.21.0-1.2-1.11.1-1.31.21.3-1.2-1.21.0-1.8-0.60.0
Pavlov. Cond. lever latency1.82.43.21.5-1.6-1.61.41.6-1.71.7-1.7-1.71.51.8-1.81.3-1.40.0
Pavlov. Cond. magazine entry latency0.20.31.00.5-0.5-0.50.60.4-0.50.4-0.4-0.40.50.5-0.51.00.20.0
Pavlov. Cond. change in total contacts1.11.51.9-1.31.31.3-1.3-1.31.3-1.41.31.4-1.1-1.41.3-1.01.30.0
Pavlov. Cond. index score0.40.50.6-0.70.70.6-0.6-0.70.7-0.80.70.8-0.6-0.80.7-0.40.80.0
Pavlov. Cond. latency score0.20.30.5-0.50.50.5-0.5-0.50.6-0.60.60.6-0.4-0.60.6-0.20.70.0
Pavlov. Cond. lever contacts1.11.52.1-1.21.31.3-1.1-1.31.4-1.41.41.4-1.1-1.51.4-1.21.00.0
Pavlov. Cond. magazine entry number0.10.10.3-0.30.30.3-0.3-0.20.2-0.20.20.2-0.3-0.20.2-0.5-0.30.0
Pavlov. Cond. intertrial magazine entries0.50.71.5-1.00.91.0-1.1-0.80.8-0.70.80.7-0.9-0.70.9-1.20.30.0
Pavlov. Cond. lever-magazine prob. diff.0.20.20.5-0.40.40.4-0.4-0.50.5-0.50.50.6-0.4-0.50.5-0.10.70.0
Pavlov. Cond. response bias0.60.81.2-0.80.90.8-0.7-0.91.0-1.11.01.1-0.8-1.01.0-0.70.70.0
Time in closed arm before self-admin0.40.40.7-0.80.60.6-0.8-0.70.7-0.70.70.7-0.8-0.60.6-0.10.8-0.3
Time in closed arm after self-admin0.00.00.20.1-0.2-0.30.10.2-0.20.1-0.2-0.10.10.3-0.2-0.0-0.40.1
Time in open arm before self-admin0.30.31.2-0.30.50.5-0.3-0.50.4-0.50.40.4-0.3-0.40.2-0.8-0.4-1.1
Time in open arm after self-admin1.51.62.2-1.31.41.4-1.3-1.41.3-1.41.41.4-1.3-1.51.2-0.70.8-1.2
Bone: periosteal estimation1.93.84.72.1-2.1-2.22.22.1-2.12.0-2.1-2.02.02.0-1.91.7-1.70.0
Bone: periosteal perimeter0.61.01.41.1-1.1-1.11.11.2-1.11.2-1.1-1.21.11.0-0.80.9-0.60.0
Bone: post-yield work0.20.30.90.4-0.5-0.70.30.5-0.60.4-0.5-0.40.30.6-0.70.5-0.90.0
Progressive ratio test 1 active lever presses0.00.00.1-0.00.10.0-0.0-0.10.1-0.20.20.2-0.0-0.20.10.1-0.1-0.2
Progressive ratio test 1 breakpoint0.00.00.1-0.10.20.1-0.1-0.20.2-0.30.20.3-0.1-0.30.10.1-0.0-0.2
Progressive ratio test 1 inactive lever presses0.91.01.41.1-1.0-1.01.11.0-1.01.0-1.0-1.01.11.0-1.00.4-0.71.2
Progressive ratio test 2 active lever presses0.00.00.10.0-0.0-0.00.00.0-0.10.0-0.0-0.00.0-0.0-0.10.10.10.4
Progressive ratio test 2 breakpoint0.00.00.1-0.10.10.0-0.1-0.10.0-0.10.10.1-0.1-0.10.0-0.10.10.3
Progressive ratio test 2 inactive lever presses0.10.20.6-0.40.40.4-0.4-0.40.3-0.40.40.3-0.4-0.20.0-0.5-0.3-0.8
Incentive Sensitization - Responses0.80.81.5-1.00.91.1-1.0-0.90.9-0.80.90.8-1.0-1.01.0-1.01.2-0.1
Incentive Sensitization - Breakpoint0.40.41.0-0.70.60.8-0.7-0.60.6-0.50.60.5-0.7-0.70.7-0.81.00.2
Sum of active levers in priming session hrs 5-60.50.51.5-0.60.70.5-0.6-0.70.5-0.90.70.8-0.6-0.50.2-0.7-0.5-1.2
Progressive ratio3.74.37.72.0-2.1-1.92.02.1-2.02.2-2.1-2.21.92.1-1.92.1-0.62.8
Food seeking constrained by brief footshock0.10.10.8-0.40.20.3-0.3-0.30.3-0.30.30.3-0.3-0.30.40.30.90.4
Seeking ratio, punishment vs. effort2.53.14.5-1.81.81.6-1.7-1.81.8-1.91.81.9-1.7-1.81.7-1.90.7-2.1
Retroperitoneal fat weight1.13.85.02.2-2.1-2.12.22.1-2.02.1-2.1-2.12.22.1-2.01.4-1.30.0
Reaction time number correct0.60.91.61.0-1.0-0.90.91.0-1.01.1-1.1-1.11.11.0-0.91.30.00.0
Reaction time mean minus median0.20.20.60.4-0.5-0.50.30.5-0.50.5-0.5-0.50.50.5-0.60.0-0.80.0
Reaction time mean minus median AUC0.20.21.20.4-0.4-0.50.30.5-0.50.3-0.4-0.40.50.4-0.50.0-1.10.0
Reaction time num false alarms0.10.11.1-0.20.30.5-0.1-0.30.4-0.10.20.1-0.3-0.30.4-0.21.00.0
Reaction time num false alarms AUC0.60.82.4-0.70.91.1-0.7-0.91.0-0.70.80.7-0.9-0.81.0-0.71.50.0
Reaction time trials correct on left0.60.91.61.0-1.0-0.90.91.0-1.01.1-1.1-1.11.11.0-0.91.30.00.0
Reaction time trials on left0.60.91.61.0-1.0-0.90.91.0-0.91.1-1.0-1.11.10.9-0.81.30.10.0
Reaction time mean0.20.31.20.5-0.5-0.60.50.5-0.50.4-0.5-0.40.50.4-0.50.1-1.10.0
Reaction time mean AUC0.50.72.00.8-0.8-0.90.80.8-0.90.7-0.8-0.70.80.7-0.90.3-1.40.0
Median of all reaction times0.20.30.90.5-0.5-0.60.60.6-0.60.5-0.5-0.40.50.4-0.50.2-1.00.0
Reaction time omissions0.00.00.10.0-0.1-0.00.00.2-0.10.3-0.2-0.30.10.2-0.1-0.00.10.0
Reaction time false alarm rate1.21.72.2-1.31.41.5-1.2-1.41.4-1.31.41.3-1.4-1.31.3-1.41.20.0
Reaction time premature initiation rate0.10.20.5-0.50.50.5-0.4-0.50.4-0.40.50.4-0.4-0.30.4-0.7-0.00.0
Reaction time premature initiations0.10.10.20.2-0.2-0.10.30.2-0.30.4-0.3-0.40.30.4-0.30.3-0.10.0
Std. dev. reaction times0.00.00.20.1-0.2-0.30.10.2-0.20.1-0.2-0.10.20.2-0.3-0.0-0.50.0
Reaction time trials completed0.60.91.61.0-1.0-0.90.91.0-0.91.1-1.0-1.11.10.9-0.81.30.10.0
Reaction time trials AUC0.60.91.60.9-1.0-0.90.91.0-0.91.1-1.0-1.11.00.9-0.81.30.10.0
Run reversals in cocaine runway, females0.30.31.10.6-0.4-0.60.60.4-0.50.2-0.3-0.20.60.3-0.50.5-1.10.2
Run reversals in cocaine runway, males0.60.62.90.6-0.3-0.40.60.4-0.60.4-0.5-0.50.60.7-0.9-0.1-1.7-1.5
Latency to leave start box in cocaine runway0.60.71.1-1.10.80.8-1.0-0.80.8-0.80.80.8-1.0-0.70.8-1.00.5-0.4
Latency to leave start box in cocaine runway, F0.60.71.1-1.00.70.7-1.0-0.70.8-0.80.80.8-1.0-0.70.9-0.90.8-0.3
Latency to leave start box in cocaine runway, M0.10.10.4-0.20.20.2-0.1-0.10.1-0.10.10.1-0.1-0.10.1-0.7-0.40.0
Std. dev. time between licks in bursts0.10.10.20.5-0.3-0.20.50.4-0.20.4-0.3-0.30.30.20.1-0.3-0.30.0
Total sessions with >9 infusions0.00.00.20.2-0.1-0.20.20.1-0.1-0.0-0.00.00.20.0-0.10.4-0.5-0.4
Short access day 1 total inactive lever presses0.10.11.2-0.30.30.1-0.3-0.30.1-0.40.30.3-0.3-0.0-0.1-0.1-0.5-1.1
Short access day 10 total inactive lever presses0.20.21.10.3-0.10.20.30.1-0.00.4-0.2-0.40.30.30.1-0.51.00.7
Short access day 1 total infusions1.01.12.9-0.91.10.9-0.9-1.01.0-1.21.11.2-0.9-1.00.8-0.9-0.1-1.7
Short access day 10 total infusions0.00.00.1-0.00.10.1-0.0-0.10.1-0.10.10.1-0.0-0.0-0.10.40.1-0.2
Short access total infusions0.10.10.80.1-0.0-0.20.10.0-0.1-0.10.00.10.10.1-0.20.1-0.9-0.8
Short access day 1 locomotion0.10.10.5-0.10.30.4-0.1-0.30.4-0.20.30.3-0.1-0.30.5-0.70.6-0.1
Short access day 10 total locomotion0.60.63.1-0.60.70.9-0.6-0.70.8-0.50.70.5-0.6-0.80.9-0.31.8-0.4
Short access total locomotion0.10.10.60.1-0.00.10.1-0.00.00.1-0.0-0.10.10.10.00.70.80.1
One hour access (0.3 mA shock)0.70.91.3-1.01.00.9-1.0-1.00.9-1.01.01.0-1.0-0.90.8-0.90.5-1.2
Compulsive drug intake2.72.83.3-1.81.71.7-1.8-1.81.7-1.81.81.8-1.8-1.71.6-0.91.7-1.0
One hour access (shock baseline)0.40.41.40.6-0.6-0.70.60.6-0.60.5-0.6-0.50.60.6-0.80.4-1.2-0.6
Social response proportion0.00.00.10.0-0.0-0.00.10.00.0-0.00.00.00.1-0.00.10.30.20.0
Social responses0.10.21.3-0.10.30.4-0.2-0.30.4-0.10.30.2-0.2-0.30.6-0.21.20.0
Social time0.20.20.8-0.50.50.6-0.5-0.50.5-0.30.40.3-0.3-0.40.6-0.50.90.0
Soleus weight0.20.60.80.9-0.8-0.80.90.8-0.80.8-0.8-0.80.80.8-0.80.7-0.70.0
Bone: stiffness1.11.82.41.4-1.4-1.51.51.5-1.41.4-1.4-1.41.31.3-1.30.9-1.50.0
Tibialis anterior weight0.82.83.4-1.71.81.8-1.7-1.81.8-1.71.81.7-1.6-1.81.8-1.61.50.0
Time to tail flick, vehicle, before self-admin2.12.23.31.6-1.5-1.31.61.6-1.51.8-1.7-1.81.61.5-1.30.6-1.01.0
Time to tail flick, vehicle, after self-admin0.20.21.1-0.40.30.4-0.4-0.40.4-0.30.40.3-0.4-0.50.40.21.00.5
Time to tail flick, test, before self-admin0.30.31.7-0.30.20.5-0.3-0.20.40.00.20.0-0.3-0.20.6-0.71.30.6
Time to tail flick, test, after self-admin0.00.00.00.1-0.1-0.10.10.1-0.10.1-0.1-0.10.10.1-0.1-0.2-0.2-0.1
Delta time to tail flick, vehicle, before/after SA1.31.32.0-1.31.11.0-1.3-1.21.1-1.41.31.4-1.3-1.31.1-0.30.9-0.4
Delta time to tail flick, test, before/after SA1.61.52.91.3-1.2-1.31.31.2-1.31.0-1.1-1.11.31.1-1.31.1-1.70.7
Tibia length2.57.28.82.6-2.9-2.82.62.8-2.92.9-2.9-2.92.63.0-3.02.9-1.80.0
Ambulatory time before self-admin0.40.40.70.6-0.6-0.40.60.6-0.50.9-0.7-0.80.60.6-0.40.40.20.6
Ambulatory time after self-admin0.20.32.5-0.20.30.5-0.2-0.30.3-0.10.20.0-0.2-0.20.20.51.60.6
Bone: tissue strength0.00.00.20.0-0.0-0.10.0-0.0-0.0-0.10.00.10.0-0.1-0.10.40.30.0
Total heroin consumption0.30.41.0-0.60.70.7-0.6-0.70.6-0.60.60.6-0.6-0.50.40.21.0-0.2
Bone: trabecular number0.91.41.9-1.31.31.2-1.4-1.31.2-1.31.31.3-1.3-1.21.0-1.20.40.0
Bone: trabecular spacing1.72.33.21.8-1.6-1.51.81.6-1.51.6-1.6-1.61.61.5-1.41.7-0.60.0
Bone: trabecular thickness0.40.50.70.6-0.7-0.80.60.7-0.80.6-0.7-0.60.70.7-0.90.8-0.80.0
Bone: trabecular tissue density0.10.10.60.1-0.3-0.30.10.2-0.30.2-0.3-0.30.20.3-0.50.80.20.0
Water consumed over 24 hours1.31.61.9-1.31.31.3-1.4-1.31.3-1.31.31.3-1.3-1.31.3-1.11.10.0
Number of responses in last shaping day1.61.77.3-1.01.20.8-1.0-1.10.9-1.41.21.4-1.0-1.00.6-1.8-1.3-2.7