Hub : Genes

Kat7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose mRNA stability Kat7 0.05 0.03 1.9e-05 0.04 0.03 0.03 0.03 4.7e-05 1.7e-04 1.1e-04 9.7e-05
2 Eye intron excision ratio chr10_80720621_80721430 0.58 0.17 4.4e-03 -0.02 -0.01 -0.02 -0.01 8.4e-01 5.1e-01 7.3e-01 5.2e-01
3 Brain mRNA stability Kat7 0.05 0.03 1.2e-03 0.03 0.04 0.04 0.03 8.0e-04 1.0e-04 3.1e-04 7.2e-04
4 NAcc intron excision ratio chr10_80732867_80737556 0.04 0.02 3.4e-06 0.04 0.04 0.05 0.04 4.0e-07 5.2e-07 1.4e-07 2.9e-07
5 NAcc isoform ratio XM_039086068.2 0.03 0.02 2.4e-04 0.02 0.03 0.02 0.03 1.7e-04 2.2e-05 1.5e-04 2.2e-05
6 NAcc intron excision ratio chr10_80734673_80737556 0.03 0.02 1.9e-03 0.02 0.02 0.02 0.02 1.5e-04 1.1e-03 8.2e-04 1.3e-03
7 Brain isoform ratio XM_063269112.1 0.03 0.02 9.7e-03 0.02 0.02 0.01 0.01 4.6e-03 1.2e-02 8.2e-02 1.4e-02
8 PL intron excision ratio chr10_80732867_80737556 0.02 0.01 4.4e-03 0.01 0.02 0.01 0.01 1.7e-02 3.8e-03 2.0e-02 4.9e-02
9 BLA isoform ratio XM_039086068.2 0.13 0.11 6.8e-03 0.03 0.03 0.01 0.02 1.4e-02 9.9e-03 1.1e-01 3.3e-02
10 PL gene expression Kat7 0.02 0.01 9.4e-03 0.02 0.01 0 0.01 5.1e-03 3.0e-02 1.8e-01 5.7e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density0.20.32.20.3-1.50.20.1-0.1-0.0-0.50.1-0.5-0.8
Area under the delay curve0.00.00.10.0-0.10.0-0.2-0.10.10.2-0.3-0.20.0
BMI with tail2.910.129.92.7-1.45.53.04.2-2.42.6-1.24.21.9
BMI without tail0.51.66.5-0.00.81.50.30.9-0.02.6-2.11.1-0.1
Body weight0.83.67.22.3-1.02.72.22.2-2.30.2-0.11.91.8
Weight adjusted by age0.30.51.7-0.60.7-0.3-0.6-0.40.71.3-0.8-0.5-0.4
Bone surface0.10.21.10.7-1.10.60.30.2-0.40.0-0.2-0.2-0.2
Bone volume0.50.93.11.3-1.81.01.00.7-1.0-0.80.60.20.2
Breakpoint value in progressive ratio session3.03.67.2-1.30.2-1.6-2.1-2.21.91.9-2.3-2.7-1.9
Number of licking bursts0.91.42.6-1.51.2-1.6-1.5-1.21.5-0.0-0.2-0.6-1.0
Context. condit. distance diff. score0.30.40.80.4-0.20.80.60.9-0.4-0.20.70.90.7
Locomotion velocity, session 10.60.62.1-0.91.5-0.2-0.7-0.20.81.2-0.90.3-0.1
Locomotion distance, session 12.02.56.6-2.02.6-1.5-1.5-1.41.31.6-1.5-0.9-0.9
Locomotion velocity, session 20.10.10.50.10.40.20.50.2-0.70.3-0.20.10.5
Locomotion distance, session 23.24.59.9-2.83.2-2.2-1.8-2.01.62.0-2.1-1.3-1.4
Locomotion velocity, session 31.51.72.81.5-0.61.71.51.5-1.50.10.41.41.6
Locomotion distance, session 30.20.20.4-0.50.6-0.5-0.4-0.50.30.7-0.6-0.5-0.2
Stereotopy head waving bouts, day 33.94.55.92.3-1.42.22.42.3-2.3-1.32.12.32.1
Stereotopy head waving duration, day 33.64.35.32.3-1.62.02.32.2-2.3-1.72.22.12.1
Locomotion velocity, session 70.50.52.20.21.50.20.40.4-0.50.7-0.20.81.1
Locomotion distance, session 71.11.33.5-1.41.7-1.9-1.3-1.31.1-0.3-0.0-0.8-0.3
Stereotopy head waving bouts, day 70.20.20.60.8-0.50.60.50.3-0.50.6-0.20.00.2
Stereotopy head waving duration, day 70.40.41.41.2-0.80.80.70.5-0.70.40.10.10.6
Locomotion velocity, session 81.11.32.80.51.01.50.91.3-0.81.4-0.51.71.2
Locomotion distance, session 80.71.12.6-1.41.6-0.6-0.7-0.70.71.6-1.2-0.4-0.6
Degree of sensitization distance0.20.21.0-0.00.3-0.3-0.00.1-0.0-1.00.80.40.5
Degree of sensitization stereotypy0.70.81.6-0.50.2-0.6-0.7-1.00.61.2-1.2-1.2-1.0
Conditioned locomotion0.70.82.60.8-1.60.60.70.6-0.5-1.40.90.20.3
Cocaine response after cond. corrected0.50.61.21.0-1.01.10.61.0-0.2-0.40.41.10.5
Cocaine response after cond. not corrected0.20.30.90.5-1.00.60.20.60.1-0.60.50.60.1
Cocaine response before conditioning0.81.02.0-1.40.4-1.4-0.9-1.10.8-0.50.0-1.2-1.1
Saline control response1.21.52.4-1.51.5-1.1-1.2-1.21.11.4-1.0-1.0-1.1
Bone: connectivity density0.71.02.8-0.4-1.2-0.4-0.7-0.90.60.5-1.0-1.6-1.7
Bone: cortical apparent density0.50.71.9-0.61.2-1.1-0.3-0.30.1-1.41.00.40.5
Bone: cortical area0.30.40.80.7-0.10.90.70.8-0.80.20.20.60.7
Bone: cortical porosity0.20.20.40.5-0.10.60.60.5-0.60.10.20.30.6
Bone: cortical porosity0.20.20.40.4-0.10.60.70.5-0.60.10.20.30.5
Bone: cortical thickness0.81.32.80.90.41.01.21.3-1.2-0.61.21.61.7
Bone: cortical thickness0.20.21.2-0.41.1-0.3-0.30.10.3-0.30.30.70.1
Bone: cortical tissue density0.50.71.9-0.71.2-1.3-0.4-0.50.2-1.40.90.20.4
Condit. Reinf. active minus inactive responses1.01.21.9-1.21.1-1.0-0.9-1.10.71.2-1.4-0.9-1.1
Condit. Reinf. active-inactive response ratio0.10.10.2-0.40.5-0.1-0.3-0.10.30.5-0.20.1-0.2
Condit. Reinf. active responses1.11.42.6-1.41.2-1.0-0.9-1.20.61.3-1.6-1.0-1.3
Condit. Reinf. inactive responses1.31.62.4-1.40.8-1.3-1.0-1.40.90.9-1.6-1.4-1.5
Incentive salience index mean2.12.63.7-1.91.8-1.4-1.4-1.61.21.8-1.9-1.3-1.5
Condit. Reinf. lever presses2.94.05.7-2.42.3-2.0-1.9-2.01.72.0-2.1-1.6-1.9
Condit. Reinf. active minus inactive responses1.51.92.9-1.50.5-1.5-1.6-1.61.60.7-1.1-1.6-1.7
Condit. Reinf. active-inactive response ratio4.65.39.6-2.31.1-2.3-2.8-2.43.11.3-1.9-2.2-2.8
Condit. Reinf. active responses0.50.61.2-1.10.6-0.7-0.9-0.80.80.7-0.6-0.9-0.9
Condit. Reinf. inactive responses0.71.02.20.50.31.01.21.1-1.5-0.10.81.11.3
Condit. Reinf. lever presses0.30.41.8-0.11.00.50.20.2-0.31.3-0.90.20.5
Condit. Reinf. lever reinforcers received0.50.81.1-1.10.6-0.8-0.9-0.90.80.8-0.9-1.0-0.9
Conditioned reinforcement - actives0.61.12.4-1.11.6-0.7-0.9-0.90.71.2-1.4-0.6-0.7
Conditioned reinforcement - inactives0.10.10.5-0.10.2-0.3-0.1-0.10.0-0.70.20.20.4
Conditioned locomotion0.20.30.8-0.70.9-0.1-0.4-0.30.20.5-0.7-0.2-0.5
Patch foraging indifference point 0 sec0.61.11.81.3-1.31.31.21.1-1.1-0.50.30.90.6
Patch foraging indifference point AUC0.70.92.30.51.40.90.80.7-0.81.5-0.61.01.1
Delay disc. indifference point, 0s delay0.10.10.6-0.30.8-0.1-0.20.00.30.4-0.20.30.4
Delay disc. indifference point, 16s delay0.50.51.31.0-0.91.10.60.8-0.60.20.00.50.6
Delay disc. indifference point, 2s delay0.30.41.10.5-1.0-0.4-0.1-0.3-0.1-1.00.8-0.70.3
Delay disc. indifference point, 24s delay0.70.82.6-0.51.1-0.2-0.8-0.40.81.6-1.3-0.4-0.8
Delay disc. indifference point, 4s delay0.10.10.40.2-0.3-0.3-0.0-0.3-0.3-0.50.1-0.60.2
Delay disc. indifference point, 8s delay0.00.10.1-0.2-0.1-0.3-0.3-0.20.3-0.3-0.0-0.1-0.2
Indifference point function ln k0.20.30.7-0.4-0.4-0.6-0.5-0.40.6-0.80.2-0.4-0.6
Indifference point function log k0.20.30.7-0.4-0.4-0.6-0.5-0.40.6-0.80.2-0.4-0.6
Patch foraging total patch changes 0 sec0.71.22.21.5-1.41.41.21.2-1.2-0.50.30.90.7
Patch foraging total patch changes 12 sec0.10.10.20.00.40.20.30.1-0.30.5-0.40.20.0
Patch foraging total patch changes 18 sec1.11.73.41.6-0.51.81.51.5-1.40.50.11.41.4
Patch foraging total patch changes 24 sec0.20.31.10.7-1.00.70.60.3-0.60.2-0.1-0.10.1
Patch foraging total patch changes 6 sec0.81.32.31.30.11.51.21.2-1.21.1-0.51.21.2
Patch foraging time to switch 0 sec0.10.30.6-0.50.4-0.7-0.7-0.50.80.00.1-0.4-0.4
Patch foraging water rate 0 sec0.91.93.81.2-0.61.91.51.8-1.4-0.20.51.91.4
Patch foraging water rate 12 sec0.20.51.40.8-0.51.20.50.9-0.40.4-0.30.70.7
Patch foraging water rate 18 sec0.20.31.1-0.3-0.9-0.3-0.4-0.30.3-1.00.2-0.5-0.5
Patch foraging water rate 24 sec0.40.61.40.7-0.51.20.71.1-0.6-0.20.31.10.7
Patch foraging water rate 6 sec0.71.03.2-1.00.7-0.2-0.8-0.50.91.8-1.6-0.5-0.9
Seeking ratio, delayed vs. immediate footshock1.11.32.01.4-1.31.41.31.3-1.0-0.80.91.00.7
Distance traveled before self-admin3.44.45.6-2.01.7-1.8-2.3-2.12.42.2-2.2-2.0-2.2
Distance traveled after self-admin1.61.93.2-1.40.8-0.9-1.5-1.21.81.6-1.5-1.1-1.7
Extensor digitorum longus weight0.83.06.32.3-1.22.51.91.9-2.10.7-0.31.51.6
Bone: elastic displacement0.10.10.5-0.20.50.2-0.00.1-0.00.7-0.50.3-0.1
Bone: elastic work0.10.10.7-0.00.50.30.00.1-0.10.8-0.40.00.1
Bone: endosteal estimation0.10.30.90.1-0.60.1-0.2-0.40.10.7-0.9-0.9-0.7
Bone: endosteal perimeter0.20.40.90.3-0.90.4-0.1-0.2-0.00.6-0.9-0.8-0.7
Epididymis fat weight0.10.41.0-0.2-0.0-0.5-0.9-0.61.00.5-0.6-0.7-0.7
Delta time in closed arm before/after self-admin0.70.71.61.2-1.20.80.90.6-1.0-0.40.40.10.8
Delta time in open arm before/after self-admin0.20.20.9-0.50.9-0.4-0.3-0.10.3-0.10.10.3-0.0
Diff in mean of infusions in LGA sessions2.22.75.1-1.72.0-1.2-1.7-1.31.72.2-2.0-0.9-0.9
Delay discount exponential model param0.00.00.10.00.10.10.30.2-0.2-0.10.30.40.1
Extinction: sum of active levers before priming0.50.51.5-0.10.2-0.5-0.6-0.90.31.0-1.1-1.2-0.3
Active lever presses in extinction session 60.30.31.80.00.40.4-0.20.20.31.3-0.60.20.1
Bone: final force0.00.10.1-0.20.1-0.3-0.2-0.10.3-0.30.3-0.0-0.1
Bone: final moment0.00.00.1-0.10.1-0.1-0.10.10.2-0.20.40.20.1
Food consumed during 24 hour testing period1.21.62.8-1.01.0-1.2-1.3-1.41.11.3-1.7-1.5-1.2
Glucose3.45.411.81.9-2.31.42.22.0-2.0-3.33.41.81.9
Heart weight0.20.42.30.5-1.50.1-0.3-0.20.2-0.2-0.1-0.8-0.5
Delay discount hyperbolic model param0.00.00.1-0.10.20.00.20.1-0.00.10.10.3-0.1
Intermittent access intake day 1-15 change0.30.62.8-0.30.7-0.2-0.5-0.50.51.3-1.7-0.2-0.2
Intermittent access intake escalation0.51.03.5-0.61.0-0.4-0.8-0.60.81.5-1.9-0.3-0.5
Intermittent access intake escalation 20.60.73.0-0.60.6-0.2-0.5-0.50.71.4-1.7-0.2-0.7
Intermitt. access day 1 inactive lever presses0.10.30.9-0.40.9-0.2-0.10.20.2-0.70.21.00.5
Intermitt. access day 15 inactive lever presses1.42.85.41.8-0.62.01.82.0-1.7-0.70.92.02.3
Intermitt. access escalation Index0.30.41.0-1.00.8-0.6-0.8-0.40.80.4-0.4-0.1-0.7
Intermittent access day 1 total infusions0.30.41.50.5-0.70.00.50.3-0.8-1.01.20.10.4
Intermittent access day 15 total infusions0.10.20.7-0.20.6-0.3-0.3-0.30.20.6-0.8-0.1-0.1
Intermittent access terminal intake (last 3 days)0.00.10.40.00.1-0.0-0.0-0.2-0.20.3-0.7-0.1-0.0
Intermittent access total infusions0.10.20.30.4-0.50.20.30.2-0.6-0.60.40.10.4
Intermittent access day 1 locomotion0.30.31.80.2-0.1-0.10.30.2-0.5-1.31.00.30.3
Intermittent access day 15 total locomotion0.00.10.20.10.1-0.3-0.1-0.3-0.30.1-0.4-0.4-0.0
Intermittent access total locomotion0.00.00.20.20.1-0.10.00.0-0.3-0.50.20.10.1
Intermittent access standard deviation0.20.40.80.70.20.80.40.6-0.30.5-0.70.70.9
Left kidney weight0.10.41.10.5-0.90.40.60.5-0.7-1.00.50.30.2
Right kidney weight0.21.02.41.0-1.61.01.20.8-1.3-1.00.60.40.5
Cocaine induced anxiety0.60.93.0-0.11.60.70.30.5-0.21.7-1.10.90.4
Post-drug Anxiety0.50.62.9-0.11.70.20.00.1-0.01.2-1.00.30.6
Baseline Anxiety0.50.52.40.1-0.7-0.7-0.3-0.60.1-1.50.8-0.90.1
Tail length2.28.522.9-2.52.2-4.8-2.8-4.11.9-0.5-1.0-4.1-2.0
Length with tail0.41.97.40.4-0.2-2.0-0.0-1.3-0.7-2.71.4-1.70.6
Length without tail1.85.710.42.7-2.51.72.31.9-2.5-3.22.71.52.3
Times rat made contact with spout0.20.20.6-0.60.2-0.8-0.4-0.60.3-0.6-0.3-0.4-0.3
Lifetime Intake0.10.20.40.4-0.50.10.30.2-0.5-0.50.60.20.3
Liver weight, left0.20.30.8-0.60.8-0.2-0.5-0.30.40.6-0.90.1-0.3
Liver weight, right0.10.10.40.5-0.30.30.40.3-0.6-0.40.00.30.3
Locomotor activity0.60.93.5-1.61.9-0.3-0.3-0.10.61.0-0.70.8-0.4
Locomotor testing distance0.40.82.8-1.41.7-0.3-0.5-0.10.81.0-0.60.8-0.5
Locomotor testing rearing0.71.44.5-1.62.1-0.6-0.8-0.41.01.5-1.10.5-0.7
Locomotion in novel chamber1.01.32.6-0.9-0.3-1.1-1.2-1.41.00.4-1.3-1.6-1.5
Locomotion in novel chamber post-restriction0.00.10.30.3-0.60.20.30.1-0.20.00.2-0.2-0.0
Fecal boli incidents, locomotor time 11.72.54.91.5-0.72.21.82.0-1.7-0.30.82.01.4
Change in fecal boli incidents, locomotor task1.21.22.2-1.30.8-1.4-1.4-1.21.50.1-0.3-1.1-0.8
Time >=10cm from walls, locomotor time 11.92.03.4-1.81.2-1.3-1.6-1.31.70.8-1.3-1.0-1.8
Bouts of movement, locomotor time 12.02.24.31.10.31.61.51.9-1.5-0.81.32.11.9
Total resting periods, locomotor time 12.42.75.11.20.01.81.72.1-1.6-1.11.52.31.9
Rest time, locomotor task time 10.50.61.20.4-0.10.60.70.9-0.6-1.00.81.10.7
Distance moved, locomotor task time 11.92.84.8-1.40.5-1.9-2.0-2.02.01.0-1.0-2.2-1.9
Vertical activity count, locomotor time 10.51.34.5-0.81.4-0.6-1.1-0.81.02.1-1.5-0.7-0.4
Time >=10cm from walls, locomotor time 20.60.91.6-1.20.5-1.1-1.1-0.91.2-0.40.0-0.6-1.3
Bouts of movement, locomotor time 20.10.10.4-0.40.5-0.0-0.4-0.00.30.1-0.60.1-0.2
Total resting periods, locomotor time 20.10.20.6-0.60.6-0.2-0.5-0.20.40.3-0.8-0.0-0.3
Rest time, locomotor task time 20.40.51.4-0.3-0.6-0.9-0.7-0.90.5-0.60.1-1.2-0.8
Distance moved, locomotor task time 20.20.31.10.4-0.20.20.50.4-0.3-0.61.10.30.7
Vertical activity count, locomotor time 20.40.61.40.31.20.60.40.6-0.31.0-0.20.91.1
Light reinforcement 10.51.22.2-1.10.8-0.7-1.1-0.91.11.4-1.5-0.7-1.4
Light reinforcement 20.81.21.8-1.30.9-1.1-1.2-1.11.10.7-1.1-0.9-1.3
Bone: marrow area0.10.30.9-0.0-0.50.1-0.2-0.40.10.8-0.9-0.9-0.7
Bone: maximum diameter0.20.30.90.0-0.50.3-0.4-0.30.30.9-1.0-0.7-0.7
Bone: maximum force0.30.50.80.9-0.70.80.70.7-0.7-0.50.70.50.8
Bone: maximum moment0.50.81.21.1-0.71.01.01.0-0.9-0.50.80.81.0
Mean time between licks in bursts0.82.03.61.5-0.51.51.51.6-1.6-0.80.91.61.9
Mean num. licks in bursts0.50.81.81.2-1.20.91.20.7-1.3-0.60.10.20.8
Cd content in liver0.80.91.5-0.7-0.1-1.2-1.0-1.20.9-0.1-0.7-1.2-1.2
Co content in liver0.10.10.5-0.20.7-0.1-0.2-0.00.30.4-0.00.20.1
Cu content in liver5.86.810.6-2.73.3-2.8-2.8-2.72.62.5-2.5-2.1-1.9
Fe content in liver0.50.61.3-0.90.5-1.1-1.0-1.00.8-0.3-0.2-0.9-0.7
K content in liver1.11.12.80.90.00.31.10.7-1.2-1.01.50.61.7
Mg content in liver0.70.72.2-0.61.0-1.5-0.8-1.00.7-0.60.4-0.80.1
Mn content in liver1.41.52.9-1.01.7-1.1-0.9-1.20.71.7-1.6-1.1-0.8
Na content in liver0.30.30.70.2-0.00.10.70.3-0.8-0.60.80.20.7
Rb content in liver2.12.45.3-1.61.7-1.4-2.1-1.42.31.3-1.2-0.9-1.2
Se content in liver0.20.20.60.0-0.8-0.4-0.2-0.40.1-0.50.4-0.7-0.5
Sr content in liver0.20.20.40.7-0.50.00.4-0.0-0.6-0.10.1-0.40.4
Zn content in liver0.40.41.1-0.3-0.3-1.1-0.5-0.90.5-0.50.2-0.9-0.5
Bone: minimum diameter0.30.62.70.8-1.60.20.6-0.0-0.7-1.00.7-0.8-0.1
Time in familiar zone, hab. session 11.11.12.0-0.8-0.2-1.4-1.3-1.21.4-0.60.2-1.1-1.2
Time in novel zone, hab. session 12.92.95.01.7-1.02.22.22.0-2.2-0.30.61.81.6
Total zone transitions, hab. session 14.56.38.5-2.82.9-2.5-2.4-2.62.22.6-2.8-2.2-2.0
Total locomotion distance, hab. session 12.73.85.9-2.32.4-1.9-1.5-2.01.12.1-2.4-1.7-1.6
Locomotion velocity, hab. session 13.14.47.2-2.52.7-2.2-1.7-2.21.42.0-2.3-1.9-1.7
Time in familiar zone, hab. session 20.10.10.40.3-0.60.4-0.20.10.20.2-0.50.1-0.4
Time in novel zone, hab. session 20.20.20.7-0.10.3-0.20.30.2-0.2-0.50.80.30.5
Total zone transitions, hab. session 23.24.16.4-2.52.3-2.2-2.0-2.11.81.7-2.0-1.7-1.7
Total locomotion distance, hab. session 20.70.92.3-1.31.5-0.9-0.4-0.90.21.1-1.0-0.7-0.5
Locomotion velocity, hab. session 20.60.81.7-1.31.3-0.9-0.4-0.90.11.0-0.9-0.8-0.6
Novel to familiar place preference ratio0.91.01.8-0.90.3-1.0-1.0-1.20.90.8-1.0-1.2-1.4
Novelty place preference0.60.71.2-0.80.3-0.9-0.8-1.00.80.7-0.8-0.9-1.1
Time in novel zone, NPP test0.50.51.0-0.80.3-0.9-0.8-0.80.90.4-0.5-0.6-1.0
Total zone transitions, NPP test3.65.29.1-3.02.9-2.7-2.2-2.51.91.7-2.0-1.9-1.8
Total locomotion distance, NPP test1.21.75.7-1.92.4-1.4-0.7-1.10.51.2-1.1-0.5-0.6
Locomotion velocity, NPP test1.11.65.3-1.72.3-1.3-0.6-1.10.31.4-1.2-0.7-0.5
Intraocular pressure0.50.81.5-0.41.2-0.7-0.9-0.80.81.2-1.2-0.6-0.5
Delta distance traveled before/after self-admin0.60.70.90.7-0.80.90.90.9-0.8-0.70.70.90.7
Delta ambulatory time before/after self-admin0.70.91.10.8-1.00.91.01.0-0.9-0.91.00.80.9
Parametrial fat weight0.41.04.10.5-1.7-0.20.20.0-0.3-2.01.5-0.4-0.1
Pavlov. Cond. lever latency2.73.46.32.5-2.41.81.91.6-2.0-1.71.61.01.6
Pavlov. Cond. magazine entry latency1.01.32.3-1.51.5-0.8-1.1-0.81.21.4-1.3-0.4-1.0
Pavlov. Cond. change in total contacts4.95.27.1-2.72.2-2.4-2.5-2.32.51.8-2.0-1.9-2.2
Pavlov. Cond. index score2.73.56.8-2.52.6-1.5-1.9-1.42.12.0-1.7-0.6-1.5
Pavlov. Cond. latency score2.32.96.5-2.32.6-1.4-1.7-1.21.81.8-1.4-0.5-1.2
Pavlov. Cond. lever contacts3.34.08.4-2.72.9-2.0-1.9-1.82.01.9-1.6-1.0-1.4
Pavlov. Cond. magazine entry number1.72.13.91.9-2.01.21.41.2-1.6-1.61.50.61.2
Pavlov. Cond. intertrial magazine entries0.60.72.6-0.2-0.5-1.1-0.6-1.20.3-0.4-0.4-1.6-0.9
Pavlov. Cond. lever-magazine prob. diff.2.93.66.5-2.52.5-1.5-2.0-1.52.22.0-1.8-0.7-1.5
Pavlov. Cond. response bias2.83.55.3-2.32.3-1.6-1.9-1.62.02.1-2.0-1.1-1.6
Pavlov. Cond. lever latency2.02.74.5-1.70.9-2.1-2.0-2.01.90.5-0.9-1.8-1.8
Pavlov. Cond. magazine entry latency0.70.82.11.2-1.20.71.20.5-1.5-0.90.30.10.7
Pavlov. Cond. change in total contacts1.21.93.11.3-0.11.81.71.7-1.6-0.00.31.71.6
Pavlov. Cond. index score1.41.93.61.6-1.01.61.81.4-1.9-0.50.51.11.3
Pavlov. Cond. latency score1.11.53.21.5-1.11.31.61.2-1.8-0.70.50.81.1
Pavlov. Cond. lever contacts1.62.24.01.4-0.52.01.81.9-1.7-0.20.71.81.6
Pavlov. Cond. magazine entry number2.32.95.4-2.01.8-1.5-2.1-1.42.31.7-1.2-0.9-1.6
Pavlov. Cond. intertrial magazine entries2.23.37.3-2.42.7-1.6-2.1-1.42.31.6-1.2-0.6-1.2
Pavlov. Cond. lever-magazine prob. diff.1.62.14.01.7-1.01.81.91.6-2.0-0.50.51.31.5
Pavlov. Cond. response bias1.92.63.91.7-0.92.01.91.9-1.9-0.71.01.71.8
Time in closed arm before self-admin2.12.75.61.3-0.32.02.02.1-1.7-0.61.12.41.8
Time in closed arm after self-admin3.53.85.72.2-1.42.22.42.2-2.2-1.11.22.01.9
Time in open arm before self-admin1.71.85.7-0.7-0.9-1.5-1.4-1.71.30.1-0.3-2.4-1.5
Time in open arm after self-admin1.11.32.0-1.20.9-1.4-1.3-1.31.10.7-0.6-1.2-1.1
Bone: periosteal estimation0.10.10.30.3-0.60.40.10.1-0.20.3-0.4-0.4-0.3
Bone: periosteal perimeter0.20.30.80.6-0.80.90.30.4-0.30.5-0.50.0-0.1
Bone: post-yield work0.91.42.21.5-0.71.51.31.4-1.3-0.40.61.21.2
Progressive ratio test 1 active lever presses0.60.71.5-1.00.5-1.2-1.0-1.00.70.3-0.2-0.9-0.9
Progressive ratio test 1 breakpoint0.50.61.3-0.90.4-1.1-0.9-1.00.60.2-0.2-0.9-0.9
Progressive ratio test 1 inactive lever presses0.20.21.1-0.40.60.20.10.50.0-0.10.51.00.3
Progressive ratio test 2 active lever presses1.11.31.9-1.21.4-0.9-1.1-1.01.11.4-1.3-0.7-0.9
Progressive ratio test 2 breakpoint1.21.42.1-1.31.4-1.0-1.2-1.01.21.4-1.4-0.8-1.0
Progressive ratio test 2 inactive lever presses0.30.41.6-0.41.30.2-0.10.30.10.9-0.70.90.2
Incentive Sensitization - Responses0.91.33.2-1.11.6-0.5-1.0-0.71.11.6-1.8-0.3-0.7
Incentive Sensitization - Breakpoint1.01.23.1-1.11.5-0.4-1.0-0.61.11.6-1.8-0.3-0.7
Sum of active levers in priming session hrs 5-61.81.64.6-0.9-0.4-1.7-1.3-1.71.0-0.1-0.5-2.1-1.4
Progressive ratio0.60.92.2-0.70.1-0.8-0.8-1.00.71.0-1.2-1.3-1.5
Food seeking constrained by brief footshock0.10.20.5-0.4-0.1-0.6-0.4-0.50.5-0.30.0-0.3-0.7
Seeking ratio, punishment vs. effort0.30.51.80.1-0.1-0.10.20.3-0.2-1.31.30.50.9
Retroperitoneal fat weight0.10.31.30.20.50.70.30.8-0.10.20.21.10.7
Reaction time number correct0.71.43.21.1-1.71.01.01.0-0.9-1.81.30.70.8
Reaction time mean minus median0.20.41.4-0.21.1-0.4-0.2-0.5-0.11.2-0.7-0.50.2
Reaction time mean minus median AUC0.30.71.1-0.61.0-1.0-0.8-1.00.50.9-0.8-1.0-0.3
Reaction time num false alarms0.91.22.3-1.41.5-0.9-1.0-0.91.01.1-1.3-0.6-0.9
Reaction time num false alarms AUC0.71.12.8-1.41.7-0.9-0.9-0.80.91.1-1.2-0.4-0.7
Reaction time trials correct on left0.71.43.21.1-1.71.01.01.0-0.9-1.81.30.70.8
Reaction time trials on left0.71.32.81.0-1.61.00.91.0-0.9-1.71.20.70.7
Reaction time mean0.20.31.10.21.10.10.40.2-0.50.7-0.40.30.7
Reaction time mean AUC0.20.41.80.01.30.10.20.1-0.30.9-0.40.40.7
Median of all reaction times0.20.20.90.10.90.20.30.2-0.40.5-0.20.50.6
Reaction time omissions0.91.34.0-0.71.7-0.6-0.8-0.80.72.0-1.7-0.6-0.4
Reaction time false alarm rate1.52.14.8-1.72.2-1.2-1.3-1.11.31.7-1.7-0.6-1.0
Reaction time premature initiation rate0.20.31.0-0.4-0.0-0.5-0.4-0.70.30.5-0.6-1.0-0.6
Reaction time premature initiations0.10.20.80.3-0.90.00.1-0.2-0.2-0.30.1-0.7-0.2
Std. dev. reaction times0.10.31.20.21.1-0.10.30.0-0.50.6-0.10.20.8
Reaction time trials completed0.71.32.81.0-1.61.00.91.0-0.9-1.71.20.70.7
Reaction time trials AUC0.71.33.21.0-1.60.90.91.0-0.9-1.81.30.70.7
Run reversals in cocaine runway, females0.10.10.30.40.20.50.50.5-0.40.20.20.50.3
Run reversals in cocaine runway, males0.10.10.9-0.0-0.00.1-0.2-0.20.11.0-0.4-0.50.1
Latency to leave start box in cocaine runway3.33.78.82.5-3.02.12.01.8-2.1-1.61.01.11.3
Latency to leave start box in cocaine runway, F5.36.112.32.9-3.52.42.42.3-2.4-2.62.21.61.7
Latency to leave start box in cocaine runway, M0.40.31.70.30.00.50.10.1-0.31.1-1.3-0.00.1
Std. dev. time between licks in bursts1.01.43.60.90.71.40.91.5-0.80.30.51.91.7
Total sessions with >9 infusions0.91.02.11.0-0.90.51.00.8-1.3-1.01.40.81.1
Short access day 1 total inactive lever presses0.20.31.0-0.40.2-0.4-0.4-0.50.10.7-1.0-0.6-0.5
Short access day 10 total inactive lever presses0.20.61.70.30.21.00.60.6-0.51.3-1.20.60.6
Short access day 1 total infusions0.81.01.90.9-0.40.81.11.1-1.1-0.61.41.21.2
Short access day 10 total infusions0.30.41.30.4-0.60.20.50.5-0.7-0.91.10.40.6
Short access total infusions0.91.22.11.1-0.90.91.11.1-1.2-1.01.51.01.2
Short access day 1 locomotion0.50.61.11.1-0.31.00.80.9-1.00.40.10.70.9
Short access day 10 total locomotion0.20.31.20.30.10.20.40.4-0.4-1.01.10.50.6
Short access total locomotion0.70.91.51.0-0.60.60.90.9-1.0-1.11.20.81.0
One hour access (0.3 mA shock)1.11.22.5-1.10.8-0.9-1.0-1.10.81.4-1.6-1.0-1.1
Compulsive drug intake1.51.83.1-1.30.4-1.6-1.8-1.61.80.3-0.7-1.5-1.2
One hour access (shock baseline)0.10.20.60.10.30.50.40.3-0.50.7-0.80.4-0.0
Social response proportion1.01.21.9-1.41.0-1.3-1.4-1.11.40.2-0.5-0.9-1.1
Social responses0.91.22.1-1.30.7-0.6-1.1-0.91.11.3-1.3-0.9-1.5
Social time1.72.43.7-1.91.9-1.0-1.5-1.11.81.9-1.6-0.6-1.6
Soleus weight1.44.15.42.2-1.72.22.32.3-2.2-1.41.82.11.9
Bone: stiffness0.10.20.60.4-0.6-0.1-0.0-0.00.0-0.80.7-0.30.2
Tibialis anterior weight0.41.54.5-0.60.5-0.4-1.0-0.91.02.1-2.0-1.1-1.1
Time to tail flick, vehicle, before self-admin0.90.91.9-1.11.2-1.4-1.1-1.11.00.2-0.4-0.8-0.5
Time to tail flick, vehicle, after self-admin0.30.40.50.7-0.70.70.60.6-0.6-0.40.40.50.5
Time to tail flick, test, before self-admin1.31.42.01.2-1.11.11.41.1-1.4-1.01.40.91.0
Time to tail flick, test, after self-admin2.62.74.91.6-1.71.21.51.5-1.6-2.22.21.31.3
Delta time to tail flick, vehicle, before/after SA1.41.32.51.1-1.11.61.31.5-1.0-0.50.91.40.7
Delta time to tail flick, test, before/after SA0.30.30.9-0.4-0.2-0.8-0.5-0.50.6-1.00.5-0.3-0.4
Tibia length1.33.55.01.8-1.31.72.11.9-2.2-1.82.21.62.0
Ambulatory time before self-admin2.74.15.7-1.91.8-1.5-2.1-1.82.12.4-2.4-1.7-2.3
Ambulatory time after self-admin0.70.81.9-0.80.1-0.7-0.9-0.91.00.6-0.8-1.0-1.4
Bone: tissue strength2.52.53.81.7-1.61.21.71.4-1.7-1.72.01.01.7
Total heroin consumption2.83.26.4-1.6-0.2-1.8-2.1-2.12.01.1-1.3-2.5-2.2
Bone: trabecular number0.81.33.6-0.6-1.3-0.9-0.8-1.30.80.0-0.8-1.9-1.9
Bone: trabecular spacing1.01.46.2-0.82.50.1-0.50.20.71.9-1.11.10.4
Bone: trabecular thickness5.16.49.52.9-3.12.63.02.4-3.0-2.32.21.51.9
Bone: trabecular tissue density1.11.63.41.2-0.10.91.41.3-1.5-1.11.31.41.9
Water consumed over 24 hours0.00.00.1-0.10.3-0.2-0.0-0.10.0-0.0-0.30.10.0
Number of responses in last shaping day1.61.83.11.8-0.51.51.51.5-1.6-0.00.41.41.7