Hub : Genes

Kat6a

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Kat6a 0.06 0.04 1.1e-03 0 0.02 0.02 0.01 2.9e-01 1.8e-03 1.8e-03 2.2e-02
2 Brain mRNA stability Kat6a 0.25 0.09 0.0e+00 0.24 0.23 0.22 0.23 8.0e-22 4.8e-21 2.8e-20 6.4e-21
3 Adipose mRNA stability Kat6a 0.07 0.04 1.2e-03 0.01 0.01 0.03 0.02 1.4e-02 7.4e-03 2.0e-04 1.2e-03
4 Brain gene expression Kat6a 0.11 0.05 6.8e-12 0.17 0.12 0.14 0.12 8.2e-16 9.8e-12 3.0e-13 1.8e-11
5 pVTA gene expression Kat6a 0.04 0.03 1.6e-04 0.04 0.04 0.03 0.03 6.6e-04 2.1e-04 2.0e-03 1.2e-03
6 IL gene expression Kat6a 0.23 0.12 1.0e-02 -0.01 0.05 0 0.03 4.7e-01 2.6e-02 2.6e-01 7.6e-02
7 NAcc gene expression Kat6a 0.03 0.02 1.4e-03 0 0 0 0 1.8e-01 8.9e-02 7.0e-02 1.6e-01
8 NAcc mRNA stability Kat6a 0.02 0.02 8.7e-03 0 0.01 0.01 0 1.6e-01 2.6e-03 1.1e-02 4.3e-02
9 NAcc intron excision ratio chr16_75805044_75806569 0.04 0.03 1.5e-03 -0 0.01 0.01 0 5.1e-01 2.1e-02 6.9e-03 2.6e-01
10 IC isoform ratio XM_063275455.1 0.12 0.08 6.9e-03 0.07 0.01 0.01 0.04 6.1e-04 1.1e-01 1.1e-01 8.2e-03
11 NAcc intron excision ratio chr16_75803949_75804883 0.04 0.02 5.1e-03 0 0.01 0.01 0 1.9e-01 3.8e-02 5.0e-03 2.9e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.50.81.2-1.01.0-0.2-1.0-0.8-1.0-1.0-0.1-1.10.81.1
Area under the delay curve1.01.22.90.5-1.40.41.61.40.51.5-1.7-0.2-1.00.0
BMI with tail2.48.318.4-4.13.5-3.2-3.2-2.6-4.3-1.80.2-2.61.22.3
BMI without tail1.03.08.5-2.92.2-2.8-2.1-1.2-2.4-0.20.5-0.6-0.30.3
Body weight3.113.630.5-5.54.9-4.4-4.3-3.6-4.9-2.20.7-2.80.82.5
Weight adjusted by age0.10.20.5-0.70.3-0.5-0.3-0.3-0.4-0.1-0.4-0.6-0.10.5
Bone surface0.81.42.9-1.71.5-0.9-1.4-1.0-1.7-0.90.1-1.10.51.0
Bone volume1.63.05.2-2.32.0-1.4-2.0-1.7-2.0-1.50.3-1.81.31.8
Breakpoint value in progressive ratio session0.10.10.7-0.50.30.0-0.3-0.1-0.1-0.3-0.00.2-0.9-0.4
Number of licking bursts0.81.34.80.71.5-0.9-1.3-1.70.8-0.82.20.30.4-0.1
Context. condit. distance diff. score0.20.31.0-0.40.4-0.1-0.3-0.0-0.1-0.00.50.9-0.9-1.0
Locomotion velocity, session 10.30.41.0-0.3-0.60.20.91.0-0.20.9-0.50.3-0.6-0.3
Locomotion distance, session 10.30.30.9-0.5-0.30.20.30.3-0.8-0.1-0.9-0.90.40.8
Locomotion velocity, session 20.81.02.4-0.50.30.3-0.5-0.6-1.0-1.2-0.3-1.51.51.6
Locomotion distance, session 21.31.85.2-0.90.7-0.7-0.9-1.0-1.3-1.1-0.7-2.31.62.2
Locomotion velocity, session 30.50.61.60.6-0.71.30.50.20.4-1.0-1.0-0.60.60.7
Locomotion distance, session 30.20.20.80.7-0.50.50.60.20.90.1-0.30.2-0.2-0.2
Stereotopy head waving bouts, day 30.70.91.71.3-1.31.11.21.11.10.5-0.70.5-0.3-0.4
Stereotopy head waving duration, day 30.70.82.81.4-1.01.70.81.00.5-0.10.10.80.4-0.6
Locomotion velocity, session 70.70.82.00.2-0.1-0.30.20.21.20.71.11.4-1.1-1.4
Locomotion distance, session 70.40.53.0-1.30.5-1.7-0.4-0.80.20.00.3-0.3-0.10.3
Stereotopy head waving bouts, day 70.60.72.31.1-0.81.50.61.10.50.3-0.70.5-0.7-0.7
Stereotopy head waving duration, day 71.31.55.61.6-1.12.40.91.60.60.3-0.71.1-0.8-1.2
Locomotion velocity, session 80.30.30.6-0.1-0.60.50.70.70.50.6-0.30.5-0.8-0.6
Locomotion distance, session 80.10.20.7-0.6-0.0-0.30.10.2-0.20.2-0.7-0.1-0.9-0.1
Degree of sensitization distance0.60.62.9-1.60.5-1.7-0.5-0.5-0.30.30.4-0.2-0.30.2
Degree of sensitization stereotypy0.70.72.81.1-0.71.70.51.10.20.2-0.60.6-0.6-0.8
Conditioned locomotion0.70.83.50.90.0-0.60.0-0.51.90.00.50.9-1.5-1.1
Cocaine response after cond. corrected0.60.72.3-1.50.3-1.3-0.40.1-1.10.5-0.6-0.9-0.10.7
Cocaine response after cond. not corrected0.40.51.5-0.2-1.0-0.30.70.9-0.01.2-0.9-0.4-0.00.3
Cocaine response before conditioning1.92.26.32.5-2.12.21.71.21.80.5-0.50.31.0-0.0
Saline control response0.50.71.6-1.20.9-0.1-1.0-0.7-0.8-0.9-0.2-0.90.30.8
Bone: connectivity density0.10.20.5-0.00.10.7-0.10.6-0.50.1-0.10.5-0.5-0.6
Bone: cortical apparent density1.52.08.6-0.10.81.0-1.0-1.1-1.1-2.01.2-1.02.91.5
Bone: cortical area5.28.016.9-4.04.1-3.3-3.6-3.6-2.2-2.22.2-1.30.81.3
Bone: cortical porosity0.10.20.8-0.00.0-0.70.20.10.20.4-0.30.1-0.9-0.2
Bone: cortical porosity0.30.31.4-0.30.2-0.8-0.0-0.10.40.50.10.4-1.2-0.6
Bone: cortical thickness2.23.78.5-2.92.7-2.0-2.3-2.3-1.8-1.31.8-0.81.10.9
Bone: cortical thickness1.92.34.9-2.21.3-1.1-1.2-1.1-2.2-1.1-0.4-1.81.31.8
Bone: cortical tissue density1.52.08.90.10.71.2-0.9-1.1-1.0-2.01.2-1.03.01.5
Condit. Reinf. active minus inactive responses0.40.51.10.9-1.10.80.90.60.90.2-0.6-0.10.20.2
Condit. Reinf. active-inactive response ratio1.31.43.81.3-1.91.11.71.51.01.3-0.90.20.1-0.1
Condit. Reinf. active responses0.81.02.11.1-1.40.71.50.91.30.6-1.4-0.3-0.50.2
Condit. Reinf. inactive responses0.50.61.80.8-0.60.61.00.41.20.0-1.3-0.0-1.1-0.2
Incentive salience index mean0.50.61.21.1-1.01.00.90.50.8-0.2-1.0-0.50.30.5
Condit. Reinf. lever presses0.81.13.91.0-1.20.81.41.10.90.5-2.0-0.2-1.2-0.1
Condit. Reinf. active minus inactive responses0.50.61.5-0.41.0-0.3-0.8-1.0-0.6-1.20.9-0.41.10.6
Condit. Reinf. active-inactive response ratio0.91.12.2-1.01.1-0.0-0.8-0.9-1.4-1.50.2-1.01.31.1
Condit. Reinf. active responses0.00.10.2-0.00.10.2-0.0-0.2-0.1-0.40.3-0.10.50.2
Condit. Reinf. inactive responses0.40.51.10.6-0.80.20.70.80.61.0-0.30.6-0.7-0.7
Condit. Reinf. lever presses0.20.31.3-0.40.40.5-0.1-0.50.0-1.10.1-0.30.70.4
Condit. Reinf. lever reinforcers received0.10.10.3-0.20.10.20.1-0.2-0.2-0.50.1-0.20.60.3
Conditioned reinforcement - actives0.20.31.3-0.80.5-1.1-0.1-0.2-0.10.7-0.00.1-0.9-0.2
Conditioned reinforcement - inactives0.10.10.3-0.50.4-0.40.3-0.3-0.40.5-0.2-0.30.00.2
Conditioned locomotion0.50.61.70.1-0.50.11.00.80.51.1-0.90.4-1.3-0.7
Patch foraging indifference point 0 sec0.50.94.1-0.5-0.80.50.70.9-0.70.3-2.0-1.30.11.1
Patch foraging indifference point AUC1.01.53.3-1.31.8-0.6-1.6-1.2-1.8-1.30.4-0.80.60.8
Delay disc. indifference point, 0s delay0.60.61.40.8-1.11.01.11.20.40.5-0.80.3-0.2-0.4
Delay disc. indifference point, 16s delay0.50.61.60.6-0.7-0.31.20.70.81.3-0.8-0.1-0.90.0
Delay disc. indifference point, 2s delay1.21.32.91.0-1.60.91.41.41.31.1-1.7-0.2-0.7-0.0
Delay disc. indifference point, 24s delay0.40.42.0-0.60.6-1.4-0.1-0.5-0.00.5-0.2-0.2-1.00.1
Delay disc. indifference point, 4s delay0.80.92.00.7-1.40.81.31.20.60.9-1.4-0.2-0.50.1
Delay disc. indifference point, 8s delay0.60.71.8-0.0-1.00.61.21.2-0.11.2-1.3-0.5-0.20.4
Indifference point function ln k1.22.05.01.8-2.21.01.81.51.91.3-0.41.0-0.3-0.8
Indifference point function log k1.22.05.01.8-2.21.01.81.51.91.3-0.41.0-0.3-0.8
Patch foraging total patch changes 0 sec0.61.14.8-0.4-1.00.60.81.0-0.70.3-2.2-1.40.21.3
Patch foraging total patch changes 12 sec0.60.82.1-1.10.70.8-0.6-0.2-1.4-1.2-0.9-1.10.31.0
Patch foraging total patch changes 18 sec0.91.43.1-0.70.41.5-0.60.1-1.8-1.4-1.4-1.60.81.4
Patch foraging total patch changes 24 sec0.30.61.8-0.70.41.1-0.40.1-1.3-1.0-0.7-0.70.40.6
Patch foraging total patch changes 6 sec0.20.20.7-0.80.5-0.7-0.3-0.4-0.3-0.2-0.3-0.6-0.00.6
Patch foraging time to switch 0 sec0.51.02.20.01.0-0.7-0.7-1.11.3-0.31.51.0-1.2-1.1
Patch foraging water rate 0 sec0.61.33.60.4-1.01.30.81.0-1.1-0.3-1.9-1.31.21.3
Patch foraging water rate 12 sec1.12.34.62.1-2.22.01.91.81.41.0-0.61.0-0.2-0.9
Patch foraging water rate 18 sec1.32.05.71.2-2.41.12.01.70.71.1-1.8-0.60.60.7
Patch foraging water rate 24 sec1.11.54.61.6-1.92.11.41.50.50.4-1.10.00.60.1
Patch foraging water rate 6 sec0.30.51.20.6-0.51.10.30.4-0.3-0.6-0.8-0.71.00.7
Seeking ratio, delayed vs. immediate footshock0.10.20.7-0.5-0.3-0.30.10.3-0.20.2-0.8-0.1-0.8-0.0
Distance traveled before self-admin0.70.92.4-0.00.6-0.5-0.9-1.10.1-1.10.1-1.51.11.6
Distance traveled after self-admin0.10.10.50.2-0.0-0.0-0.2-0.30.3-0.3-0.2-0.70.30.7
Extensor digitorum longus weight0.62.55.7-2.22.4-1.6-2.2-1.7-2.0-0.91.3-0.30.20.2
Bone: elastic displacement0.50.61.70.4-0.81.30.40.9-0.9-0.1-0.8-0.61.10.7
Bone: elastic work0.50.62.3-1.50.2-0.3-0.10.5-1.50.4-1.1-0.6-0.60.4
Bone: endosteal estimation0.40.91.9-1.01.4-0.9-1.3-1.3-0.3-1.30.4-0.6-0.00.6
Bone: endosteal perimeter0.61.33.9-1.51.7-2.0-1.2-1.30.1-0.30.80.2-1.2-0.4
Epididymis fat weight1.55.111.2-3.02.7-3.4-2.4-2.6-1.8-1.20.5-2.31.02.2
Delta time in closed arm before/after self-admin0.80.71.6-1.10.9-0.7-0.5-1.1-0.9-0.6-0.4-1.20.21.1
Delta time in open arm before/after self-admin0.20.20.6-0.2-0.6-0.0-0.20.8-0.60.2-0.30.2-0.0-0.2
Diff in mean of infusions in LGA sessions0.60.74.1-0.60.3-0.40.00.30.00.7-0.11.0-2.0-1.2
Delay discount exponential model param1.11.33.4-0.41.4-0.4-1.6-1.4-0.6-1.51.80.31.0-0.1
Extinction: sum of active levers before priming0.30.31.0-1.00.8-0.3-0.8-0.4-0.5-0.6-0.0-0.5-0.10.4
Active lever presses in extinction session 60.60.62.7-1.20.9-1.7-0.8-0.6-0.40.10.5-0.2-0.20.1
Bone: final force4.06.314.1-3.83.7-2.8-3.2-3.2-1.9-2.21.7-1.00.10.9
Bone: final moment3.45.413.5-3.73.5-2.6-2.9-2.9-1.9-2.01.3-1.0-0.10.8
Food consumed during 24 hour testing period0.30.41.3-0.50.80.4-0.8-0.4-1.1-0.80.90.10.6-0.0
Glucose0.60.92.40.7-1.21.61.11.4-0.40.7-1.4-0.1-0.10.0
Heart weight1.11.65.9-0.71.6-1.0-1.8-1.7-0.4-0.82.40.41.0-0.2
Delay discount hyperbolic model param1.41.63.8-0.61.7-0.6-1.8-1.6-0.7-1.61.90.21.10.1
Intermittent access intake day 1-15 change0.71.43.7-1.41.6-1.9-1.5-1.4-0.9-0.41.1-0.50.60.5
Intermittent access intake escalation0.51.02.4-1.21.5-1.5-1.3-1.1-0.8-0.21.1-0.20.40.2
Intermittent access intake escalation 21.61.83.7-1.21.9-1.3-1.9-1.8-0.9-1.31.5-0.51.10.7
Intermitt. access day 1 inactive lever presses0.10.20.6-0.10.1-0.00.4-0.3-0.30.1-0.3-0.80.70.8
Intermitt. access day 15 inactive lever presses0.10.20.7-0.60.2-0.60.4-0.0-0.20.8-0.8-0.5-0.40.3
Intermitt. access escalation Index1.31.83.9-1.31.8-1.4-2.0-1.6-1.2-1.21.7-0.30.90.5
Intermittent access day 1 total infusions0.81.22.00.7-0.91.11.21.30.61.2-0.51.3-1.4-1.4
Intermittent access day 15 total infusions0.30.41.0-0.40.3-0.50.10.2-0.01.00.30.9-0.9-1.0
Intermittent access terminal intake (last 3 days)0.10.10.5-0.1-0.1-0.10.40.30.10.7-0.40.3-0.6-0.4
Intermittent access total infusions0.50.51.00.4-0.60.61.00.80.41.0-0.50.7-0.8-0.8
Intermittent access day 1 locomotion1.51.93.90.7-1.30.81.91.60.62.0-1.31.1-1.6-1.3
Intermittent access day 15 total locomotion0.40.72.00.0-0.6-0.41.00.70.41.4-0.90.4-1.4-0.7
Intermittent access total locomotion0.81.02.30.6-1.00.71.51.10.61.4-1.20.4-0.9-0.6
Intermittent access standard deviation0.10.20.6-0.20.8-0.2-0.1-0.30.10.30.70.7-0.4-0.7
Left kidney weight0.62.610.1-3.21.6-1.9-1.1-0.6-2.80.3-0.7-1.2-0.20.8
Right kidney weight1.25.615.5-3.93.3-2.1-3.0-1.8-3.7-1.31.2-0.70.30.5
Cocaine induced anxiety0.40.52.00.6-0.71.40.71.0-0.00.3-0.40.7-0.5-0.7
Post-drug Anxiety0.30.30.90.5-0.71.00.40.50.2-0.1-0.7-0.50.50.6
Baseline Anxiety2.02.34.5-1.21.3-2.1-1.5-1.8-0.3-1.10.2-2.11.32.1
Tail length0.31.02.1-1.21.0-1.2-1.0-0.2-0.30.50.81.1-1.4-1.2
Length with tail0.72.98.4-2.92.5-2.2-2.0-1.6-2.0-0.70.5-0.9-0.40.6
Length without tail0.92.96.3-2.52.2-1.4-1.7-1.7-2.4-1.4-0.1-1.60.31.4
Times rat made contact with spout0.60.72.70.60.41.1-0.4-0.3-0.6-1.10.5-0.61.60.8
Lifetime Intake0.70.81.40.8-0.81.21.01.00.70.9-0.40.9-0.8-1.0
Liver weight, left0.20.30.7-0.50.3-0.8-0.00.1-0.70.4-0.6-0.1-0.8-0.1
Liver weight, right1.52.610.3-2.51.4-0.5-1.3-0.4-3.2-1.0-1.0-1.70.91.5
Locomotor activity0.71.12.9-1.1-0.6-0.40.40.7-1.50.5-1.7-1.5-0.21.3
Locomotor testing distance0.30.61.5-0.8-0.3-0.30.20.5-1.10.5-1.2-1.0-0.20.9
Locomotor testing rearing0.30.72.1-0.40.30.1-0.3-0.3-0.8-0.8-1.0-1.50.61.4
Locomotion in novel chamber1.01.33.4-0.0-1.40.71.11.50.11.1-1.50.6-1.8-0.9
Locomotion in novel chamber post-restriction1.01.64.0-1.7-0.8-2.00.60.9-1.01.6-2.0-1.0-0.70.7
Fecal boli incidents, locomotor time 10.10.10.40.4-0.40.70.30.40.2-0.3-0.50.0-0.00.0
Change in fecal boli incidents, locomotor task0.20.20.6-0.3-0.20.00.30.1-0.50.3-0.7-0.5-0.50.4
Time >=10cm from walls, locomotor time 10.10.10.3-0.20.3-0.0-0.3-0.4-0.5-0.30.60.00.30.0
Bouts of movement, locomotor time 11.11.23.41.9-1.61.51.60.71.20.6-0.20.10.90.1
Total resting periods, locomotor time 10.91.02.61.6-1.21.61.10.40.70.00.1-0.11.40.4
Rest time, locomotor task time 10.81.03.71.7-0.81.60.80.30.5-0.50.60.31.90.2
Distance moved, locomotor task time 10.50.71.6-1.20.5-1.2-1.0-0.50.1-0.4-0.8-0.9-1.20.6
Vertical activity count, locomotor time 10.30.72.3-1.20.1-1.0-0.50.0-0.10.2-1.2-0.9-1.50.6
Time >=10cm from walls, locomotor time 20.40.62.20.3-1.01.50.31.1-0.8-0.1-0.10.70.7-0.6
Bouts of movement, locomotor time 20.00.10.20.40.10.2-0.3-0.30.1-0.40.4-0.20.20.2
Total resting periods, locomotor time 20.10.20.40.30.3-0.0-0.4-0.50.1-0.40.6-0.50.60.6
Rest time, locomotor task time 20.50.61.81.20.2-0.40.2-0.71.40.00.9-0.51.00.8
Distance moved, locomotor task time 20.40.51.5-1.20.3-0.3-1.00.2-1.0-0.3-0.10.5-0.9-0.8
Vertical activity count, locomotor time 20.20.31.0-0.1-0.60.5-0.10.8-0.1-0.1-1.00.2-0.8-0.4
Light reinforcement 10.41.03.60.0-1.1-0.11.01.3-0.21.5-1.9-0.7-0.90.3
Light reinforcement 22.43.711.00.9-1.20.22.01.71.92.4-1.22.0-3.3-2.5
Bone: marrow area0.40.91.8-1.01.3-0.8-1.3-1.3-0.3-1.30.4-0.6-0.00.6
Bone: maximum diameter1.93.68.8-2.43.0-2.3-2.6-2.6-0.9-1.61.6-0.4-0.20.3
Bone: maximum force2.64.613.1-3.63.0-2.5-2.5-2.6-1.6-1.71.0-1.20.21.1
Bone: maximum moment2.13.711.9-3.42.7-2.2-2.1-2.2-1.5-1.50.7-1.1-0.01.0
Mean time between licks in bursts1.02.48.20.8-0.20.50.70.91.01.31.32.9-1.9-2.9
Mean num. licks in bursts0.81.23.4-0.5-1.01.40.81.1-1.3-0.2-1.9-1.10.91.0
Cd content in liver1.01.22.4-1.30.8-0.6-0.9-0.9-1.2-0.80.2-1.31.51.4
Co content in liver1.31.53.7-1.91.3-1.4-1.2-1.1-1.2-0.7-0.0-1.40.61.4
Cu content in liver0.91.12.90.7-0.40.70.81.00.80.90.11.6-1.7-1.7
Fe content in liver0.60.73.10.2-0.61.10.90.9-0.20.2-1.7-0.6-0.80.3
K content in liver0.40.31.1-0.4-0.1-1.10.30.10.70.9-0.10.3-0.8-0.4
Mg content in liver0.30.31.2-0.6-0.4-0.60.50.6-0.11.1-0.60.0-0.5-0.1
Mn content in liver0.20.20.70.40.4-0.7-0.2-0.60.9-0.00.60.1-0.1-0.1
Na content in liver1.01.14.40.2-0.6-0.10.91.01.01.3-1.20.5-2.1-0.9
Rb content in liver0.30.31.70.5-0.51.30.50.60.0-0.2-0.00.70.2-0.6
Se content in liver2.42.85.22.3-1.71.32.21.81.61.5-1.51.1-1.8-1.3
Sr content in liver0.30.31.0-0.30.3-1.0-0.3-0.60.70.30.90.3-0.1-0.2
Zn content in liver0.20.20.7-0.5-0.3-0.70.20.5-0.40.8-0.10.4-0.6-0.5
Bone: minimum diameter2.74.911.4-2.23.4-1.8-3.0-3.3-0.7-2.82.2-0.90.80.9
Time in familiar zone, hab. session 10.30.31.30.5-0.10.7-0.1-0.40.3-0.70.7-0.11.10.4
Time in novel zone, hab. session 11.01.03.2-1.81.2-1.0-0.9-0.1-1.70.1-0.4-0.3-1.0-0.0
Total zone transitions, hab. session 10.20.31.4-0.5-0.50.20.50.6-0.40.5-1.2-0.6-0.40.4
Total locomotion distance, hab. session 10.50.72.1-1.50.2-0.8-0.00.2-1.10.4-1.1-1.1-0.20.9
Locomotion velocity, hab. session 10.30.41.1-0.7-0.4-0.30.40.6-0.60.7-1.1-0.6-0.20.4
Time in familiar zone, hab. session 20.20.21.30.5-0.11.10.10.40.2-0.10.10.6-0.4-0.6
Time in novel zone, hab. session 20.80.82.3-1.40.5-1.5-0.4-0.5-1.00.1-0.4-1.00.51.0
Total zone transitions, hab. session 20.10.10.7-0.50.1-0.8-0.0-0.1-0.20.4-0.4-0.3-0.40.2
Total locomotion distance, hab. session 20.40.52.0-0.4-0.6-0.60.60.6-0.20.9-1.4-0.7-0.50.4
Locomotion velocity, hab. session 20.40.62.3-0.3-0.7-0.80.60.6-0.11.0-1.5-0.8-0.50.5
Novel to familiar place preference ratio1.11.23.5-1.70.9-1.5-0.7-0.4-1.90.10.1-1.00.91.0
Novelty place preference1.21.34.0-1.91.0-1.7-0.8-0.4-2.00.20.2-0.90.70.9
Time in novel zone, NPP test1.11.14.2-1.80.9-1.5-0.6-0.2-2.00.30.0-0.80.60.8
Total zone transitions, NPP test0.60.92.4-1.20.7-0.8-0.6-0.7-0.8-0.7-0.9-1.60.21.4
Total locomotion distance, NPP test0.81.14.1-0.9-0.0-1.1-0.0-0.2-0.50.0-1.6-2.00.31.8
Locomotion velocity, NPP test0.81.24.2-1.00.1-1.2-0.1-0.4-0.4-0.1-1.5-2.10.31.8
Intraocular pressure1.72.56.2-1.50.5-2.3-0.10.6-1.02.40.61.6-2.5-1.9
Delta distance traveled before/after self-admin0.30.40.80.3-0.50.10.50.70.30.8-0.10.9-0.8-0.9
Delta ambulatory time before/after self-admin0.20.20.70.6-0.60.80.50.60.30.3-0.10.40.1-0.4
Parametrial fat weight0.41.03.5-1.51.2-1.9-1.0-0.4-1.40.2-0.2-0.4-0.80.1
Pavlov. Cond. lever latency0.40.41.8-0.30.7-0.3-0.8-0.7-0.5-0.41.30.10.90.1
Pavlov. Cond. magazine entry latency0.20.30.80.4-0.60.90.50.8-0.50.2-0.60.2-0.1-0.2
Pavlov. Cond. change in total contacts0.91.02.10.6-0.80.01.01.30.41.4-0.71.0-1.4-1.2
Pavlov. Cond. index score0.40.51.11.0-0.71.00.70.90.40.3-0.60.5-0.6-0.6
Pavlov. Cond. latency score0.50.61.11.1-0.81.00.71.00.50.4-0.70.7-0.8-0.8
Pavlov. Cond. lever contacts0.50.61.50.8-0.90.60.90.90.60.5-1.20.2-0.7-0.3
Pavlov. Cond. magazine entry number0.20.20.9-0.60.2-1.0-0.1-0.50.30.1-0.1-0.5-0.00.5
Pavlov. Cond. intertrial magazine entries0.30.41.0-0.20.30.3-0.3-0.6-0.3-1.0-0.1-0.91.01.0
Pavlov. Cond. lever-magazine prob. diff.0.50.61.11.1-0.91.00.91.00.40.5-0.80.5-0.6-0.6
Pavlov. Cond. response bias0.20.30.70.7-0.70.70.70.60.20.3-0.9-0.0-0.2-0.1
Pavlov. Cond. lever latency0.30.42.4-0.20.6-1.5-0.5-0.5-0.00.80.5-0.3-0.40.2
Pavlov. Cond. magazine entry latency2.22.77.22.0-0.71.90.40.32.1-0.32.02.7-0.2-2.3
Pavlov. Cond. change in total contacts0.30.42.10.3-0.31.40.30.40.1-0.50.41.00.0-0.9
Pavlov. Cond. index score0.60.92.90.9-0.71.70.60.31.2-0.60.51.30.1-1.0
Pavlov. Cond. latency score0.71.03.01.1-0.81.70.70.51.4-0.40.41.3-0.0-1.1
Pavlov. Cond. lever contacts0.30.42.20.3-0.41.50.30.20.1-1.0-0.20.20.7-0.1
Pavlov. Cond. magazine entry number0.70.82.3-0.70.1-1.10.10.1-1.00.6-1.5-1.5-0.41.2
Pavlov. Cond. intertrial magazine entries0.60.84.5-0.80.8-2.1-0.7-0.8-0.80.50.6-0.70.50.7
Pavlov. Cond. lever-magazine prob. diff.0.50.72.70.7-0.61.70.50.31.1-0.70.51.10.2-0.9
Pavlov. Cond. response bias0.40.52.20.5-0.31.50.10.10.3-0.90.50.80.6-0.6
Time in closed arm before self-admin0.91.13.50.7-0.81.20.41.20.10.50.71.9-0.7-1.7
Time in closed arm after self-admin0.20.20.80.3-0.00.9-0.3-0.2-0.3-0.90.30.10.4-0.0
Time in open arm before self-admin0.50.51.1-0.20.2-0.90.7-0.21.00.9-0.9-0.6-1.10.3
Time in open arm after self-admin1.01.12.80.0-1.2-0.51.11.50.21.7-1.40.4-1.3-0.7
Bone: periosteal estimation2.24.710.3-2.93.2-2.4-2.9-2.8-1.4-2.11.4-1.20.41.1
Bone: periosteal perimeter2.03.58.5-2.52.9-2.5-2.4-2.4-0.9-1.31.6-0.4-0.40.2
Bone: post-yield work0.10.10.4-0.30.5-0.5-0.2-0.60.6-0.10.50.2-0.2-0.1
Progressive ratio test 1 active lever presses0.20.31.00.6-0.41.00.60.60.30.3-0.30.5-0.2-0.5
Progressive ratio test 1 breakpoint0.30.41.20.7-0.61.10.70.70.30.4-0.30.5-0.3-0.6
Progressive ratio test 1 inactive lever presses0.81.22.50.9-1.31.31.61.40.51.2-1.00.7-0.6-0.8
Progressive ratio test 2 active lever presses1.82.14.20.9-1.60.91.91.81.02.1-1.11.2-1.6-1.4
Progressive ratio test 2 breakpoint1.92.24.50.9-1.60.91.91.91.02.1-1.21.2-1.6-1.4
Progressive ratio test 2 inactive lever presses0.30.51.70.0-0.3-0.11.10.50.31.3-0.90.1-0.9-0.3
Incentive Sensitization - Responses1.82.66.30.5-1.50.32.21.81.22.5-1.70.8-2.3-1.1
Incentive Sensitization - Breakpoint2.12.76.50.6-1.70.42.31.91.22.6-1.80.8-2.3-1.1
Sum of active levers in priming session hrs 5-60.80.71.80.4-0.60.71.01.00.70.9-0.90.6-1.3-0.8
Progressive ratio0.20.41.1-1.10.7-0.9-0.3-0.2-0.70.50.00.3-0.7-0.5
Food seeking constrained by brief footshock0.40.53.51.5-0.30.10.30.01.9-0.1-0.10.1-0.2-0.0
Seeking ratio, punishment vs. effort0.60.83.21.8-0.60.80.2-0.01.6-0.80.2-0.31.00.6
Retroperitoneal fat weight0.52.25.3-2.32.1-2.0-1.9-1.4-1.5-0.51.50.1-0.0-0.1
Reaction time number correct0.81.54.70.5-0.80.20.1-0.2-0.1-0.8-1.3-2.02.02.2
Reaction time mean minus median0.51.32.91.5-1.61.41.71.31.01.0-0.90.4-0.0-0.3
Reaction time mean minus median AUC0.30.81.71.3-1.20.91.30.91.00.8-0.50.2-0.0-0.1
Reaction time num false alarms2.23.17.2-2.31.7-2.7-2.0-1.5-1.8-0.7-0.2-2.10.71.9
Reaction time num false alarms AUC1.72.76.4-2.41.2-2.5-1.4-0.9-1.8-0.1-1.0-2.20.31.9
Reaction time trials correct on left0.81.54.70.5-0.80.20.1-0.2-0.1-0.8-1.3-2.02.02.2
Reaction time trials on left0.81.54.60.5-0.90.30.2-0.1-0.2-0.7-1.3-2.02.02.1
Reaction time mean0.50.82.40.7-0.10.50.40.50.80.71.01.5-0.8-1.5
Reaction time mean AUC0.30.61.60.6-0.20.50.60.50.60.70.71.3-0.6-1.2
Median of all reaction times0.60.92.90.40.50.0-0.2-0.00.60.41.61.7-0.8-1.6
Reaction time omissions1.52.25.80.0-1.10.21.31.80.12.3-0.71.6-2.4-1.9
Reaction time false alarm rate1.21.75.9-2.21.3-2.4-1.1-0.7-1.40.4-0.4-1.0-0.70.7
Reaction time premature initiation rate0.40.62.8-0.00.9-0.5-1.1-0.8-0.2-0.61.70.40.2-0.3
Reaction time premature initiations0.40.71.70.30.5-0.2-1.0-1.0-0.2-1.21.1-0.61.30.9
Std. dev. reaction times1.12.03.71.2-1.81.21.81.91.01.9-0.71.3-1.0-1.3
Reaction time trials completed0.81.54.60.5-0.90.30.2-0.1-0.2-0.7-1.3-2.02.02.1
Reaction time trials AUC0.91.65.30.2-0.40.1-0.3-0.5-0.4-1.1-1.0-2.22.22.3
Run reversals in cocaine runway, females0.30.31.60.2-0.1-1.30.0-0.10.80.50.0-0.40.30.5
Run reversals in cocaine runway, males0.80.82.2-1.30.0-0.30.0-0.2-1.50.0-1.0-1.30.71.2
Latency to leave start box in cocaine runway0.30.30.90.2-0.60.40.90.80.20.8-0.7-0.0-0.1-0.1
Latency to leave start box in cocaine runway, F0.20.20.90.4-0.41.00.50.50.10.20.00.30.3-0.3
Latency to leave start box in cocaine runway, M0.40.41.20.2-0.6-0.40.80.60.61.1-0.40.3-0.6-0.3
Std. dev. time between licks in bursts0.10.20.8-0.60.6-0.3-0.4-0.2-0.3-0.2-0.20.2-0.9-0.3
Total sessions with >9 infusions1.31.62.81.1-1.31.71.21.50.91.0-0.31.5-1.3-1.6
Short access day 1 total inactive lever presses0.40.51.30.5-0.60.30.30.80.50.70.11.1-1.1-1.2
Short access day 10 total inactive lever presses0.41.02.5-1.01.6-0.9-1.3-1.4-0.5-0.91.2-0.10.40.2
Short access day 1 total infusions0.60.82.51.0-1.21.61.01.10.70.4-0.60.6-0.6-0.6
Short access day 10 total infusions0.30.31.70.8-0.11.30.00.10.5-0.60.40.50.2-0.4
Short access total infusions1.11.44.01.3-1.42.01.21.40.90.6-0.61.0-0.7-1.1
Short access day 1 locomotion0.91.12.40.7-0.81.20.91.20.70.8-0.11.5-1.4-1.5
Short access day 10 total locomotion0.10.20.40.4-0.50.40.60.40.00.50.10.30.4-0.2
Short access total locomotion0.50.61.00.7-0.90.70.80.90.60.7-0.31.0-0.8-1.0
One hour access (0.3 mA shock)0.20.20.9-0.50.3-0.7-0.1-0.00.20.60.20.4-1.0-0.6
Compulsive drug intake0.50.62.1-0.10.5-0.0-0.6-0.9-0.4-0.90.6-0.91.51.1
One hour access (shock baseline)0.30.51.9-0.10.1-0.40.30.30.40.80.11.0-1.4-1.2
Social response proportion0.20.20.60.1-0.40.60.30.3-0.3-0.3-0.8-0.70.30.7
Social responses0.50.62.0-0.60.10.1-0.5-0.2-0.6-0.8-1.0-1.40.21.3
Social time0.40.52.0-0.3-0.90.80.60.9-0.50.2-1.4-0.6-0.10.5
Soleus weight0.61.75.4-2.31.9-1.3-1.9-1.1-1.5-0.70.5-0.4-0.60.1
Bone: stiffness1.52.45.8-1.82.4-0.8-2.1-2.2-0.4-1.92.00.30.1-0.2
Tibialis anterior weight0.51.63.1-1.61.8-1.3-1.8-1.5-1.6-1.01.1-0.40.70.4
Time to tail flick, vehicle, before self-admin0.90.92.70.5-1.31.41.31.1-0.10.4-1.7-0.2-0.10.1
Time to tail flick, vehicle, after self-admin0.30.41.2-0.6-0.2-1.00.50.4-0.21.1-0.60.1-0.7-0.2
Time to tail flick, test, before self-admin0.50.51.51.1-1.21.00.50.90.6-0.1-0.6-0.00.50.1
Time to tail flick, test, after self-admin2.52.65.31.7-2.10.72.31.81.81.6-2.30.1-1.3-0.3
Delta time to tail flick, vehicle, before/after SA0.50.42.2-0.30.3-1.5-0.1-0.20.61.00.60.5-0.5-0.5
Delta time to tail flick, test, before/after SA0.70.72.00.1-0.4-0.71.30.60.51.4-1.20.0-1.2-0.2
Tibia length2.77.414.4-3.03.8-1.7-3.5-3.1-3.0-3.12.3-1.42.11.6
Ambulatory time before self-admin0.20.31.30.10.0-0.2-0.3-0.40.4-0.6-0.7-1.10.21.1
Ambulatory time after self-admin0.30.31.2-0.0-0.60.40.00.2-0.0-0.3-1.1-0.90.10.8
Bone: tissue strength0.50.52.0-0.4-0.11.40.20.8-0.50.10.10.9-0.5-1.0
Total heroin consumption0.30.41.4-0.40.60.7-0.7-0.5-1.1-1.20.0-0.20.00.1
Bone: trabecular number0.10.10.6-0.20.10.2-0.1-0.0-0.2-0.4-0.8-0.60.00.5
Bone: trabecular spacing0.50.71.9-0.2-0.2-1.30.30.30.31.40.61.1-0.9-1.0
Bone: trabecular thickness0.70.91.7-1.31.3-0.3-1.2-0.9-1.1-1.00.4-0.80.40.8
Bone: trabecular tissue density0.20.31.11.1-0.10.3-0.0-0.41.0-0.40.80.50.3-0.3
Water consumed over 24 hours1.31.84.5-0.41.30.5-1.5-1.2-1.1-2.10.8-1.32.01.4
Number of responses in last shaping day1.11.22.20.5-1.40.51.51.50.81.4-1.40.3-1.1-0.5