Kansl1l

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA alternative TSS XM_039084612.1 0.16 0.09 1.5e-03 0.07 0.06 0.06 0.08 4.4e-04 1.1e-03 1.0e-03 2.9e-04
2 IL mRNA stability Kansl1l 0.34 0.19 4.7e-03 -0.01 0.07 0.03 0.04 5.8e-01 8.1e-03 6.2e-02 4.6e-02
3 Adipose alternative TSS XM_039084606.1 0.1 0.05 1.0e-08 0.01 0.02 0.02 0.02 4.2e-02 1.3e-03 3.4e-03 5.7e-03
4 Brain isoform ratio XM_039084628.1 0.03 0.02 7.7e-03 0.01 0.02 0.01 0.01 3.9e-02 9.7e-03 1.5e-02 4.4e-02
5 Brain mRNA stability Kansl1l 0.04 0.02 3.4e-03 0.03 0.02 0.02 0.02 1.2e-03 3.9e-03 1.2e-02 2.6e-03
6 Adipose alternative TSS XM_039084608.1 0.08 0.05 3.4e-04 0 0 -0 -0 2.2e-01 3.1e-01 6.3e-01 5.6e-01
7 Adipose alternative TSS XM_039084605.1 0.03 0.02 3.3e-03 -0 -0 0 -0 6.4e-01 8.0e-01 2.4e-01 4.3e-01
8 LHb mRNA stability Kansl1l 0.27 0.13 7.8e-04 0.04 0.06 0.01 0.08 4.8e-02 1.6e-02 1.9e-01 5.1e-03
9 Adipose alternative TSS XM_039084605.1 0.03 0.02 5.7e-03 -0 -0 0 0 5.5e-01 5.9e-01 8.1e-02 3.4e-01
10 Adipose alternative TSS XM_039084608.1 0.08 0.04 1.6e-04 -0 0 -0 -0 3.8e-01 2.3e-01 7.7e-01 7.3e-01
11 Adipose intron excision ratio chr9_68300220_68306570 0.15 0.08 4.2e-10 0.05 0.05 0.05 0.05 1.2e-06 2.4e-06 1.3e-06 4.0e-06
12 NAcc mRNA stability Kansl1l 0.04 0.03 1.7e-03 0.02 0.01 0.01 0.01 1.5e-03 8.1e-03 7.6e-03 1.0e-02
13 Adipose isoform ratio XM_039084608.1 0.08 0.04 4.9e-05 -0 0 -0 -0 5.6e-01 8.7e-02 3.9e-01 6.8e-01
14 Adipose isoform ratio XM_039084605.1 0.03 0.02 3.8e-03 -0 -0 0 0 5.5e-01 6.8e-01 1.2e-01 1.8e-01
15 Liver mRNA stability Kansl1l 0.07 0.04 2.1e-03 0 0.01 0.04 0.02 9.9e-02 1.2e-02 4.5e-05 3.6e-03
16 Adipose gene expression Kansl1l 0.08 0.04 1.5e-06 0.04 0.05 0.04 0.04 3.9e-05 5.2e-06 1.6e-05 9.2e-06
17 Brain alternative TSS XM_039084608.1 0.02 0.02 6.5e-03 0 0.01 -0 0.01 9.9e-02 3.7e-02 7.7e-01 7.8e-02
18 Adipose alternative TSS XM_039084606.1 0.11 0.05 1.9e-09 0.05 0.03 0.03 0.03 3.7e-06 3.3e-04 4.8e-04 2.9e-04
19 Adipose isoform ratio XM_039084606.1 0.12 0.05 3.5e-10 0.05 0.03 0.03 0.03 2.3e-06 1.4e-04 2.6e-04 2.4e-04
20 Adipose intron excision ratio chr9_68300220_68316808 0.14 0.08 6.1e-10 0.05 0.05 0.06 0.05 1.5e-06 1.4e-06 8.1e-07 2.7e-06
21 Adipose isoform ratio XM_039084625.1 0.07 0.04 9.1e-04 0 0.01 0.01 0 2.5e-01 1.4e-02 2.3e-02 1.2e-01
22 Adipose mRNA stability Kansl1l 0.08 0.04 3.0e-05 0.02 0.01 0.01 0.01 4.2e-03 4.6e-02 5.7e-02 2.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.40.71.90.2-0.20.6-1.00.20.9-0.8-1.1-0.9-1.41.21.2-1.3-1.00.8-0.4-0.5-1.0-1.0-0.20.20.8
Area under the delay curve0.20.21.40.3-0.1-0.10.5-0.2-0.40.40.10.30.5-0.1-0.10.50.4-0.40.80.10.30.30.4-1.20.7
BMI with tail3.09.722.7-4.34.0-3.84.0-4.8-2.53.53.03.42.2-2.9-2.92.22.9-0.63.91.52.82.82.8-2.9-0.4
BMI without tail0.71.46.3-2.21.7-1.41.3-2.5-0.41.20.61.10.2-0.7-0.70.30.80.11.70.30.50.51.3-1.50.5
Body weight0.52.26.71.1-0.51.2-0.5-0.72.6-1.0-1.4-1.1-1.51.51.5-1.5-1.12.41.0-1.5-1.5-1.51.3-2.21.8
Weight adjusted by age0.20.20.5-0.60.6-0.70.7-0.4-0.50.40.40.30.3-0.2-0.20.30.20.00.5-0.10.50.50.5-0.60.4
Bone surface0.71.22.5-0.1-0.50.9-1.00.31.2-1.1-1.2-1.1-1.51.31.3-1.6-1.31.1-0.8-1.5-1.1-1.1-0.90.20.7
Bone volume1.32.13.51.1-1.31.6-1.81.01.5-1.6-1.8-1.6-1.81.91.9-1.7-1.61.0-1.1-1.2-1.6-1.6-1.00.50.9
Breakpoint value in progressive ratio session0.30.32.21.5-0.10.1-0.10.60.50.30.50.40.4-0.6-0.60.50.6-0.30.10.90.20.20.30.4-1.1
Number of licking bursts0.30.41.2-0.80.8-0.2-0.0-0.60.7-0.1-0.4-0.2-1.10.20.2-1.1-0.60.80.4-0.8-0.4-0.40.7-0.40.9
Context. condit. distance diff. score0.20.20.70.00.3-0.10.2-0.90.40.0-0.2-0.10.00.00.00.10.1-0.00.80.5-0.7-0.70.8-0.80.4
Locomotion velocity, session 10.50.52.20.1-0.90.5-0.61.2-0.6-0.3-0.1-0.20.20.10.10.1-0.2-1.2-1.5-0.20.30.3-0.81.5-1.0
Locomotion distance, session 10.30.43.7-0.5-0.1-0.20.3-0.4-0.50.50.30.50.7-0.5-0.50.60.6-1.90.00.50.60.60.00.0-0.5
Locomotion velocity, session 21.01.13.9-1.1-0.10.6-0.5-0.51.1-1.0-1.1-1.0-1.51.11.1-1.6-1.41.2-0.3-2.0-0.6-0.60.3-0.51.5
Locomotion distance, session 20.40.51.7-1.00.6-0.70.8-0.9-0.50.60.70.60.7-0.8-0.80.60.5-1.30.50.30.90.90.4-0.4-0.3
Locomotion velocity, session 31.11.23.50.20.9-1.00.8-0.7-1.21.31.01.31.0-1.3-1.31.21.4-1.41.21.91.11.10.8-0.3-1.0
Locomotion distance, session 31.11.23.41.1-1.71.5-1.51.3-0.1-1.1-1.2-1.0-0.70.90.9-0.7-0.8-0.7-1.7-0.7-0.8-0.8-1.81.2-0.3
Stereotopy head waving bouts, day 36.77.912.3-1.93.2-3.42.9-1.7-3.03.13.53.22.8-3.5-3.52.83.0-1.92.02.93.23.22.10.1-2.8
Stereotopy head waving duration, day 35.36.314.0-1.93.7-3.52.6-2.0-2.52.83.02.81.8-3.0-3.02.02.4-0.32.52.92.52.52.5-0.2-1.9
Locomotion velocity, session 71.01.13.20.3-1.81.5-0.5-0.31.0-1.0-1.3-1.1-0.21.21.2-0.3-0.6-0.5-0.3-1.2-1.2-1.2-1.3-1.21.2
Locomotion distance, session 71.72.25.70.1-2.42.1-1.10.11.2-1.8-1.8-1.9-0.81.61.6-1.0-1.5-0.1-1.2-2.3-1.6-1.6-1.7-0.71.3
Stereotopy head waving bouts, day 70.10.10.4-0.50.5-0.30.1-0.50.10.1-0.10.1-0.40.30.3-0.3-0.10.60.4-0.0-0.1-0.10.2-0.30.6
Stereotopy head waving duration, day 70.70.84.0-0.31.3-1.00.8-1.40.30.90.30.80.1-0.1-0.10.30.70.52.01.20.00.01.1-1.60.9
Locomotion velocity, session 80.30.41.9-1.40.7-0.70.4-0.6-1.30.50.20.50.2-0.3-0.30.20.3-1.20.20.20.40.40.00.0-0.0
Locomotion distance, session 80.10.10.7-0.50.1-0.10.3-0.80.00.1-0.00.10.2-0.3-0.30.20.1-0.80.40.0-0.1-0.10.4-0.60.1
Degree of sensitization distance0.40.42.0-0.90.2-0.20.8-1.20.6-0.00.1-0.10.3-0.2-0.20.2-0.00.50.8-0.7-0.1-0.10.8-1.40.8
Degree of sensitization stereotypy0.70.83.2-0.4-0.10.4-0.4-0.61.0-0.4-1.1-0.5-1.01.21.2-1.0-0.71.10.4-0.8-0.9-0.9-0.2-1.11.8
Conditioned locomotion0.70.82.70.2-0.20.6-0.90.61.0-0.7-1.0-0.7-1.50.90.9-1.4-1.11.6-0.5-1.0-0.7-0.70.00.40.8
Cocaine response after cond. corrected0.30.41.60.1-0.60.5-0.80.90.2-0.5-0.3-0.5-0.40.30.3-0.4-0.6-0.3-1.2-0.3-0.2-0.2-1.21.3-0.1
Cocaine response after cond. not corrected1.11.22.40.9-1.41.3-1.31.31.0-1.3-1.0-1.3-0.71.01.0-0.8-1.10.1-1.5-0.8-1.1-1.1-1.50.90.6
Cocaine response before conditioning1.41.63.61.3-1.41.5-0.80.41.7-1.5-1.3-1.5-0.81.21.2-0.9-1.21.3-0.2-1.3-1.9-1.9-0.4-1.01.6
Saline control response0.60.83.7-1.91.5-1.21.0-1.2-0.40.90.70.90.0-0.9-0.9-0.00.50.70.7-0.21.01.01.0-0.2-0.3
Bone: connectivity density0.30.52.1-1.40.6-0.20.2-1.20.5-0.3-0.5-0.4-0.80.50.5-0.8-0.70.90.5-1.0-0.6-0.60.3-0.91.1
Bone: cortical apparent density2.73.68.2-2.91.9-2.22.7-2.2-1.81.82.41.82.2-2.3-2.31.91.7-1.01.50.41.81.81.4-1.1-0.7
Bone: cortical area0.81.23.00.2-1.41.3-1.00.90.9-1.4-1.0-1.3-0.81.21.2-1.0-1.3-0.1-1.5-1.7-1.2-1.2-1.20.60.5
Bone: cortical porosity5.25.610.13.1-2.22.7-3.23.12.4-2.6-2.4-2.5-2.72.32.3-2.6-2.42.1-2.5-1.4-2.2-2.2-1.42.10.4
Bone: cortical porosity5.76.211.23.2-2.12.7-3.43.32.5-2.7-2.5-2.6-3.02.32.3-2.8-2.62.3-2.7-1.5-2.2-2.2-1.42.40.3
Bone: cortical thickness0.50.82.9-0.8-1.30.9-0.50.30.4-1.0-0.8-1.0-0.31.01.0-0.5-1.0-0.8-1.3-1.7-0.9-0.9-1.10.20.8
Bone: cortical thickness0.40.51.70.5-0.80.6-0.71.20.2-0.7-0.2-0.6-0.10.30.3-0.2-0.5-0.2-1.3-0.3-0.4-0.4-1.31.3-0.3
Bone: cortical tissue density3.03.98.5-2.92.0-2.32.8-2.4-1.81.92.41.92.2-2.4-2.42.01.7-1.01.60.51.91.91.5-1.2-0.7
Condit. Reinf. active minus inactive responses0.80.94.7-0.60.40.1-1.01.10.3-0.5-0.4-0.4-1.40.30.3-1.4-0.90.9-1.6-0.90.30.3-0.32.2-1.1
Condit. Reinf. active-inactive response ratio0.30.42.0-0.60.6-0.4-0.20.4-0.20.40.20.5-0.4-0.3-0.3-0.40.10.3-0.70.10.90.90.41.4-1.3
Condit. Reinf. active responses1.11.43.8-0.2-0.30.8-1.51.40.9-1.1-1.0-1.0-1.80.90.9-1.8-1.51.0-1.9-1.6-0.3-0.3-0.61.9-0.5
Condit. Reinf. inactive responses0.80.91.80.3-0.71.0-1.11.00.9-1.2-1.0-1.1-1.20.90.9-1.2-1.30.6-1.2-1.3-0.8-0.8-0.80.80.4
Incentive salience index mean0.81.03.4-0.60.00.4-1.21.10.5-0.9-0.7-0.8-1.60.70.7-1.6-1.30.7-1.7-1.4-0.1-0.1-0.51.8-0.2
Condit. Reinf. lever presses0.30.41.10.3-0.50.6-0.70.90.7-0.8-0.5-0.8-0.70.60.6-0.8-0.9-0.3-0.9-1.0-0.2-0.2-0.10.60.5
Condit. Reinf. active minus inactive responses4.55.69.82.1-2.82.8-3.03.11.9-2.7-2.5-2.6-2.22.32.3-2.3-2.50.4-3.1-2.2-2.0-2.0-2.32.01.0
Condit. Reinf. active-inactive response ratio4.54.87.92.3-2.72.7-2.82.82.1-2.5-2.4-2.4-1.92.22.2-1.9-2.1-0.2-2.7-1.5-2.0-2.0-2.21.71.0
Condit. Reinf. active responses2.63.77.11.5-2.22.2-2.42.61.2-2.2-1.9-2.2-1.91.71.7-2.0-2.20.7-2.7-2.0-1.6-1.6-1.71.80.5
Condit. Reinf. inactive responses0.20.31.80.2-0.00.2-0.30.5-0.1-0.5-0.1-0.5-0.60.00.0-0.7-0.61.3-0.5-0.8-0.4-0.40.30.4-0.1
Condit. Reinf. lever presses0.20.21.10.6-0.60.3-0.31.0-0.2-0.20.2-0.20.4-0.4-0.40.30.0-0.7-0.90.10.00.0-0.31.0-0.7
Condit. Reinf. lever reinforcers received3.04.27.41.9-2.42.4-2.52.71.5-2.4-2.1-2.3-1.91.91.9-2.0-2.30.7-2.7-2.0-1.9-1.9-1.81.70.7
Conditioned reinforcement - actives0.10.10.7-0.00.3-0.20.5-0.20.20.30.20.40.2-0.1-0.10.20.3-0.10.6-0.1-0.3-0.30.8-0.70.1
Conditioned reinforcement - inactives1.11.25.92.4-1.81.5-0.82.01.1-0.9-0.7-0.90.10.70.7-0.1-0.5-0.8-0.9-0.8-1.1-1.1-1.2-0.20.3
Conditioned locomotion5.16.111.6-1.01.3-2.23.2-2.3-1.53.02.32.83.4-2.2-2.23.33.2-2.73.02.01.51.53.1-3.0-0.6
Patch foraging indifference point 0 sec0.20.42.4-1.61.0-0.80.8-0.7-0.20.30.50.3-0.0-0.6-0.6-0.2-0.10.40.2-1.00.20.20.4-0.30.2
Patch foraging indifference point AUC0.10.10.40.4-0.60.5-0.50.00.3-0.5-0.5-0.5-0.30.50.5-0.2-0.40.3-0.1-0.0-0.4-0.4-0.4-0.10.1
Delay disc. indifference point, 0s delay0.70.71.6-0.60.5-0.81.1-1.2-0.80.90.70.91.1-0.7-0.71.11.0-0.61.20.80.60.60.7-1.30.2
Delay disc. indifference point, 16s delay0.20.21.40.4-0.2-0.10.50.1-0.40.30.20.20.8-0.2-0.20.70.4-1.20.40.30.50.50.0-0.80.4
Delay disc. indifference point, 2s delay1.51.73.4-0.20.4-1.01.5-1.1-1.21.51.01.41.7-1.0-1.01.71.6-1.61.81.41.01.01.4-1.80.0
Delay disc. indifference point, 24s delay0.30.31.0-1.00.9-0.50.4-0.4-0.10.1-0.0-0.0-0.60.10.1-0.6-0.40.90.4-0.8-0.1-0.10.3-0.50.9
Delay disc. indifference point, 4s delay0.50.51.0-0.70.4-0.60.9-1.0-0.90.70.50.70.8-0.4-0.40.80.8-0.11.00.60.60.60.4-1.00.4
Delay disc. indifference point, 8s delay0.40.41.80.3-0.60.6-0.20.20.6-0.5-0.7-0.6-0.40.70.7-0.5-0.50.30.1-0.9-0.6-0.6-0.2-1.01.3
Indifference point function ln k1.52.03.5-0.91.6-1.71.8-1.1-1.41.61.91.61.6-1.7-1.71.51.6-0.81.51.21.01.01.7-0.8-0.7
Indifference point function log k1.52.03.5-0.91.6-1.71.8-1.1-1.41.61.91.61.6-1.7-1.71.51.6-0.81.51.21.01.01.7-0.8-0.7
Patch foraging total patch changes 0 sec0.20.42.0-1.41.1-0.90.9-0.6-0.30.50.70.50.0-0.8-0.8-0.10.10.30.2-0.80.30.30.6-0.1-0.0
Patch foraging total patch changes 12 sec0.00.00.1-0.30.1-0.20.1-0.20.10.00.20.00.2-0.2-0.20.20.0-0.0-0.10.10.00.0-0.10.3-0.4
Patch foraging total patch changes 18 sec0.20.33.0-1.70.8-0.70.4-0.9-0.30.30.30.3-0.2-0.5-0.5-0.3-0.1-0.00.1-0.40.10.1-0.70.10.1
Patch foraging total patch changes 24 sec0.10.20.7-0.3-0.1-0.20.5-0.2-0.20.20.50.30.8-0.5-0.50.70.4-0.8-0.10.10.30.3-0.30.0-0.5
Patch foraging total patch changes 6 sec0.40.63.3-1.81.2-0.80.6-1.40.20.30.00.2-0.6-0.2-0.2-0.6-0.21.00.8-0.70.00.00.8-0.80.7
Patch foraging time to switch 0 sec0.20.20.70.5-0.50.5-0.80.40.8-0.0-0.50.0-0.40.30.3-0.40.1-0.5-0.70.20.10.1-0.80.8-0.3
Patch foraging water rate 0 sec0.30.41.8-0.6-0.10.00.3-0.5-0.0-0.5-0.3-0.6-0.20.60.6-0.3-0.60.50.4-0.8-0.9-0.90.9-1.11.3
Patch foraging water rate 12 sec0.91.44.0-1.31.1-1.31.0-0.7-2.01.31.11.31.0-1.3-1.31.01.1-1.60.61.11.51.50.80.1-0.7
Patch foraging water rate 18 sec0.10.20.90.60.2-0.2-0.10.8-0.5-0.00.6-0.00.2-0.3-0.30.30.0-0.4-0.40.50.30.30.61.0-0.6
Patch foraging water rate 24 sec0.10.21.0-0.2-0.10.2-0.40.1-0.0-0.4-0.4-0.4-0.60.40.4-0.5-0.50.1-0.2-0.1-0.5-0.5-0.40.21.0
Patch foraging water rate 6 sec1.31.97.7-2.81.9-2.01.6-1.9-1.91.31.31.30.8-1.1-1.10.80.9-0.81.20.61.41.40.9-0.5-0.0
Seeking ratio, delayed vs. immediate footshock0.10.21.11.1-0.10.2-0.50.80.2-0.2-0.2-0.1-0.30.20.2-0.2-0.1-0.1-0.40.4-0.1-0.1-0.40.6-0.4
Distance traveled before self-admin0.30.31.91.4-0.60.6-0.40.80.8-0.3-0.4-0.3-0.10.30.3-0.1-0.10.9-0.00.1-0.8-0.80.9-0.1-0.1
Distance traveled after self-admin0.30.42.20.1-0.90.60.3-0.60.6-0.4-0.4-0.50.50.50.50.4-0.00.20.4-0.4-0.5-0.50.8-1.50.9
Extensor digitorum longus weight0.62.511.4-3.42.5-1.91.8-3.0-0.21.10.61.0-0.4-0.8-0.8-0.40.31.52.0-0.80.70.72.3-1.91.0
Bone: elastic displacement1.21.44.5-1.61.3-1.51.0-0.4-2.11.11.41.21.0-1.4-1.40.90.8-0.20.10.81.31.30.20.9-1.5
Bone: elastic work0.20.30.9-0.4-0.20.2-0.50.5-0.1-0.5-0.3-0.4-0.50.30.3-0.6-0.60.6-0.9-0.7-0.2-0.2-0.70.9-0.3
Bone: endosteal estimation0.92.06.22.5-1.41.7-1.81.81.7-1.5-1.4-1.5-1.41.31.3-1.3-1.21.3-1.1-0.6-1.4-1.4-0.60.80.0
Bone: endosteal perimeter0.30.62.51.6-0.30.7-1.11.20.8-0.7-0.6-0.6-1.00.60.6-0.9-0.60.7-0.50.0-0.5-0.5-0.40.8-0.3
Epididymis fat weight2.45.617.30.5-1.11.9-1.2-0.33.1-2.3-2.5-2.4-2.72.62.6-2.8-2.64.20.1-3.2-2.7-2.70.8-1.93.0
Delta time in closed arm before/after self-admin1.11.13.1-1.21.0-0.3-0.2-0.80.5-0.6-0.8-0.6-1.70.90.9-1.7-1.31.60.3-1.4-0.6-0.60.7-0.51.7
Delta time in open arm before/after self-admin1.61.68.62.9-0.90.3-0.02.1-0.30.70.80.71.5-1.1-1.11.61.4-1.1-0.21.80.60.60.00.5-1.9
Diff in mean of infusions in LGA sessions4.34.710.8-2.13.3-3.02.2-1.8-2.32.52.42.61.3-2.5-2.51.42.0-0.31.92.02.22.22.8-0.1-1.5
Delay discount exponential model param0.20.21.3-0.30.00.2-0.60.20.4-0.4-0.1-0.3-0.50.10.1-0.5-0.40.2-0.8-0.2-0.4-0.4-0.41.2-0.7
Extinction: sum of active levers before priming1.31.33.90.80.8-0.91.2-0.5-0.11.21.21.21.2-1.3-1.31.31.4-0.81.61.40.40.42.0-1.1-0.7
Active lever presses in extinction session 60.10.10.50.3-0.60.5-0.30.40.3-0.3-0.3-0.3-0.10.20.2-0.1-0.2-0.0-0.4-0.3-0.0-0.0-0.70.1-0.0
Bone: final force0.91.53.71.9-1.91.7-1.41.41.5-1.4-1.2-1.4-0.61.31.3-0.7-1.0-0.3-1.1-0.7-1.4-1.4-0.90.30.4
Bone: final moment0.71.12.71.5-1.61.5-1.21.11.2-1.2-1.1-1.2-0.51.11.1-0.6-0.9-0.4-1.0-0.6-1.2-1.2-0.80.30.3
Food consumed during 24 hour testing period0.50.64.02.0-0.60.3-0.11.0-0.10.00.40.10.9-0.5-0.51.00.6-1.20.11.5-0.3-0.30.10.4-0.6
Glucose0.20.31.6-0.60.4-0.20.5-1.0-0.10.1-0.20.0-0.20.00.0-0.2-0.01.00.8-0.60.10.1-0.1-1.30.9
Heart weight0.71.04.1-0.81.0-0.7-0.10.7-1.70.40.60.5-0.4-0.8-0.8-0.4-0.00.4-1.0-0.11.71.70.32.0-1.7
Delay discount hyperbolic model param0.30.31.5-0.1-0.10.3-0.70.30.5-0.5-0.2-0.4-0.60.20.2-0.6-0.50.3-0.9-0.3-0.5-0.5-0.51.2-0.7
Intermittent access intake day 1-15 change0.50.41.3-0.01.1-1.00.60.4-1.00.80.70.80.3-0.7-0.70.40.5-0.40.50.70.80.80.60.1-0.3
Intermittent access intake escalation1.11.12.30.11.5-1.40.80.4-1.41.21.21.20.6-1.2-1.20.70.9-0.50.61.21.31.30.90.4-0.9
Intermittent access intake escalation 21.31.32.60.01.6-1.50.90.5-1.51.41.41.40.7-1.4-1.40.81.1-0.40.71.51.41.40.90.5-1.0
Intermitt. access day 1 inactive lever presses0.30.31.00.9-1.00.7-0.30.80.4-0.40.0-0.40.4-0.0-0.00.3-0.1-1.0-0.7-0.3-0.5-0.5-0.30.5-0.8
Intermitt. access day 15 inactive lever presses0.40.54.62.1-0.30.3-0.11.40.6-0.30.4-0.30.5-0.3-0.30.50.1-0.6-0.00.7-0.5-0.50.40.3-0.8
Intermitt. access escalation Index2.32.03.7-1.11.9-1.71.3-1.2-1.71.51.71.51.0-1.5-1.51.11.3-0.51.11.51.91.91.60.2-1.3
Intermittent access day 1 total infusions0.40.51.80.2-1.31.0-0.4-0.10.8-0.6-0.7-0.50.20.80.80.1-0.1-1.0-0.6-0.5-0.8-0.8-1.0-0.20.0
Intermittent access day 15 total infusions0.30.31.2-0.20.2-0.40.7-0.3-0.30.70.50.70.8-0.4-0.40.70.8-1.10.50.30.30.30.4-0.6-0.3
Intermittent access terminal intake (last 3 days)1.01.11.8-0.51.0-1.21.2-0.4-0.81.31.31.31.3-1.1-1.11.31.3-1.30.81.10.70.70.9-0.3-1.1
Intermittent access total infusions0.30.32.50.4-0.80.40.3-0.00.30.00.00.10.90.10.10.80.5-1.60.00.1-0.4-0.4-0.5-0.6-0.3
Intermittent access day 1 locomotion0.60.64.10.3-1.80.90.2-0.00.5-0.2-0.1-0.21.30.30.31.10.4-2.0-0.5-0.4-0.2-0.2-1.0-0.6-0.1
Intermittent access day 15 total locomotion0.91.07.10.2-0.4-0.20.9-0.3-0.51.00.80.91.7-0.7-0.71.61.3-2.70.60.80.70.70.2-0.8-0.7
Intermittent access total locomotion1.21.46.7-0.2-0.3-0.51.4-0.6-0.61.31.01.22.1-0.9-0.91.91.6-2.60.80.70.80.80.3-1.2-0.5
Intermittent access standard deviation1.61.74.12.0-0.5-0.20.81.2-1.01.31.31.42.0-1.4-1.41.91.8-1.40.21.41.01.0-0.40.0-2.0
Left kidney weight0.20.74.90.40.60.1-0.4-0.31.0-0.4-0.6-0.3-1.40.50.5-1.2-0.72.20.5-0.5-0.5-0.51.3-0.40.5
Right kidney weight1.02.810.20.4-0.21.1-1.30.22.2-1.6-1.7-1.6-2.51.61.6-2.4-2.03.2-0.3-1.8-1.9-1.90.4-0.21.6
Cocaine induced anxiety0.40.51.40.90.2-0.30.5-0.2-0.40.50.90.50.9-0.9-0.91.00.8-0.40.61.20.20.20.6-0.0-0.9
Post-drug Anxiety0.50.62.7-0.21.0-0.80.9-1.0-0.20.50.90.50.6-0.9-0.90.60.50.11.30.9-0.0-0.01.6-0.90.2
Baseline Anxiety0.50.51.6-1.30.9-0.4-0.1-0.10.2-0.3-0.4-0.3-1.10.50.5-1.1-0.81.3-0.0-0.8-0.4-0.40.10.01.1
Tail length7.422.532.04.3-4.85.5-5.43.95.7-5.4-5.5-5.4-5.15.45.4-5.0-5.23.6-3.8-4.1-5.4-5.4-2.61.43.2
Length with tail7.126.143.66.3-5.36.1-5.64.86.6-5.7-5.6-5.8-5.15.75.7-5.1-5.34.5-3.4-4.2-5.7-5.7-1.60.83.3
Length without tail1.73.78.32.9-1.82.2-1.51.82.8-2.2-1.7-2.2-1.61.91.9-1.7-1.92.5-0.6-1.9-2.2-2.20.2-0.71.5
Times rat made contact with spout0.50.62.01.2-0.80.4-0.41.2-0.2-0.20.4-0.20.8-0.5-0.50.70.2-1.4-0.90.7-0.1-0.1-0.31.3-1.1
Lifetime Intake0.30.31.70.1-0.70.30.5-0.30.5-0.00.00.01.00.20.20.80.5-1.30.2-0.0-0.5-0.5-0.1-1.0-0.1
Liver weight, left0.61.03.01.7-1.11.2-1.41.60.8-1.2-0.8-1.1-0.90.70.7-0.8-0.90.4-1.3-0.4-0.6-0.6-0.51.3-0.4
Liver weight, right0.30.52.71.6-0.70.5-0.31.30.3-0.10.50.00.5-0.3-0.30.50.3-0.6-0.70.20.40.40.31.0-1.5
Locomotor activity0.40.63.5-0.30.8-0.81.0-0.2-0.10.61.00.70.8-1.3-1.30.70.60.10.40.20.60.61.9-0.2-0.6
Locomotor testing distance0.20.31.4-0.50.7-0.70.60.10.00.20.80.30.5-0.9-0.90.40.1-0.0-0.10.10.20.21.20.4-0.1
Locomotor testing rearing0.10.21.7-0.10.5-0.40.40.00.30.10.60.10.3-0.5-0.50.20.10.60.00.00.20.21.30.2-0.2
Locomotion in novel chamber1.41.73.4-1.21.8-1.71.4-1.2-1.51.61.41.50.9-1.5-1.51.01.3-0.51.31.31.41.40.9-0.3-0.8
Locomotion in novel chamber post-restriction0.10.20.8-0.9-0.10.00.1-0.1-0.3-0.2-0.2-0.3-0.30.10.1-0.4-0.50.6-0.1-0.9-0.2-0.2-0.5-0.30.9
Fecal boli incidents, locomotor time 11.21.33.71.8-1.01.3-1.21.21.9-1.3-1.0-1.2-1.01.11.1-0.9-1.10.4-0.7-0.5-1.6-1.60.50.40.3
Change in fecal boli incidents, locomotor task0.50.51.70.1-0.1-0.30.30.4-1.30.60.50.60.8-0.6-0.60.70.6-0.4-0.30.31.01.0-1.10.4-0.8
Time >=10cm from walls, locomotor time 11.31.35.90.7-1.60.9-0.71.6-0.6-0.50.1-0.40.60.00.00.5-0.1-2.0-2.0-0.20.70.7-2.41.8-1.2
Bouts of movement, locomotor time 10.40.43.00.1-0.00.1-0.51.20.0-0.40.2-0.3-0.3-0.1-0.1-0.3-0.40.5-1.3-0.30.10.1-1.21.7-1.0
Total resting periods, locomotor time 10.40.53.2-0.2-0.20.1-0.51.00.1-0.40.3-0.3-0.1-0.1-0.1-0.2-0.40.1-1.4-0.40.00.0-1.61.8-1.1
Rest time, locomotor task time 10.20.32.10.30.3-0.1-0.31.10.4-0.20.4-0.1-0.2-0.3-0.3-0.2-0.30.1-0.9-0.1-0.0-0.0-0.11.5-0.9
Distance moved, locomotor task time 10.80.92.9-0.3-1.41.1-0.4-0.90.7-0.8-1.4-0.9-0.41.21.2-0.5-0.6-0.00.2-1.2-0.7-0.7-0.4-1.61.7
Vertical activity count, locomotor time 10.20.21.1-0.6-0.40.20.1-1.0-0.3-0.1-0.5-0.20.10.40.40.1-0.0-0.50.4-0.20.20.2-0.2-0.90.7
Time >=10cm from walls, locomotor time 20.50.51.80.9-0.50.1-0.21.0-0.80.30.50.40.7-0.4-0.40.70.6-1.3-0.60.80.60.6-0.41.0-1.3
Bouts of movement, locomotor time 20.40.42.4-1.50.9-0.80.9-0.8-0.50.50.70.50.3-0.5-0.50.20.30.40.4-0.40.60.60.4-0.30.0
Total resting periods, locomotor time 20.20.21.2-1.10.7-0.60.7-0.3-0.30.40.70.40.4-0.6-0.60.30.20.00.1-0.30.50.50.30.1-0.2
Rest time, locomotor task time 20.60.73.20.30.00.3-0.91.40.8-0.9-0.2-0.8-1.00.40.4-1.0-1.10.6-1.4-0.9-0.2-0.2-0.61.8-0.3
Distance moved, locomotor task time 20.30.43.1-0.2-0.70.40.4-1.10.20.2-0.40.10.50.20.20.40.4-0.50.8-0.2-0.2-0.20.7-1.80.7
Vertical activity count, locomotor time 21.92.14.5-1.41.4-1.51.7-2.1-1.01.61.21.51.3-1.3-1.31.41.6-0.62.11.31.01.02.1-1.6-0.2
Light reinforcement 11.12.17.2-1.92.7-2.21.4-1.8-1.21.51.31.50.3-1.3-1.30.50.90.61.71.51.01.02.2-0.3-0.5
Light reinforcement 20.10.20.90.9-0.10.4-0.80.50.4-0.2-0.5-0.2-0.70.40.4-0.5-0.20.2-0.10.50.10.1-0.00.5-0.5
Bone: marrow area0.92.05.72.4-1.41.7-1.81.81.7-1.6-1.4-1.5-1.51.31.3-1.4-1.31.3-1.2-0.7-1.5-1.5-0.60.80.1
Bone: maximum diameter0.61.12.31.1-1.01.2-1.31.51.0-1.1-0.8-1.1-1.20.90.9-1.2-1.10.7-1.4-1.2-0.7-0.7-1.01.1-0.3
Bone: maximum force0.40.72.41.6-1.41.2-0.90.91.1-0.9-0.9-1.0-0.30.80.8-0.3-0.5-0.6-0.6-0.1-1.1-1.1-0.70.10.2
Bone: maximum moment0.20.41.31.1-1.00.8-0.70.60.7-0.6-0.7-0.7-0.20.60.6-0.1-0.3-0.7-0.40.1-0.8-0.8-0.50.10.0
Mean time between licks in bursts0.50.71.5-0.10.9-0.91.2-0.6-0.10.71.20.60.9-1.2-1.20.80.70.11.10.40.70.71.2-0.7-0.5
Mean num. licks in bursts0.60.72.11.1-1.00.3-0.01.0-0.80.00.70.11.4-0.5-0.51.40.7-1.4-0.71.00.30.3-0.91.0-1.3
Cd content in liver0.60.62.10.60.6-0.60.5-0.2-0.51.00.71.00.7-0.8-0.80.91.2-0.20.81.41.01.00.6-0.2-0.9
Co content in liver0.10.10.70.3-0.50.20.2-0.30.20.3-0.20.20.40.00.00.40.50.10.40.1-0.1-0.1-0.3-0.90.3
Cu content in liver1.21.54.20.2-0.91.2-0.80.11.5-1.1-1.4-1.2-1.31.31.3-1.4-1.32.1-0.3-2.0-1.3-1.3-0.3-0.91.3
Fe content in liver0.20.31.00.40.10.2-0.60.70.8-0.6-0.2-0.6-0.70.10.1-0.6-0.70.5-0.6-0.0-0.5-0.50.71.0-0.2
K content in liver0.20.21.0-1.00.4-0.30.4-0.90.50.2-0.00.1-0.1-0.1-0.1-0.1-0.00.60.5-0.5-0.3-0.30.4-0.80.6
Mg content in liver0.30.31.3-1.20.9-0.70.6-1.0-0.10.50.20.5-0.0-0.3-0.3-0.00.30.60.8-0.00.10.10.6-0.70.4
Mn content in liver2.22.58.1-2.42.8-2.51.6-1.6-1.31.81.71.80.5-1.7-1.70.51.10.51.31.01.61.61.90.1-0.7
Na content in liver0.60.71.30.1-0.40.7-0.90.50.9-0.9-1.0-0.9-1.10.80.8-1.1-1.10.9-0.7-0.8-0.9-0.9-0.20.50.5
Rb content in liver0.10.20.5-0.6-0.50.10.5-0.2-0.30.30.30.30.7-0.3-0.30.40.4-0.6-0.3-0.70.50.5-0.3-0.3-0.2
Se content in liver0.40.53.50.00.8-0.50.5-0.60.60.20.30.2-0.2-0.4-0.4-0.10.01.61.00.00.10.11.9-0.70.3
Sr content in liver0.60.52.7-0.91.1-0.70.10.5-0.3-0.10.9-0.0-0.5-0.7-0.7-0.5-0.51.1-0.7-0.50.40.40.21.6-0.9
Zn content in liver0.20.32.30.3-0.20.20.4-0.70.40.2-0.20.10.20.10.10.10.30.60.9-0.3-0.1-0.10.6-1.50.8
Bone: minimum diameter1.63.04.61.5-1.72.0-2.01.72.1-2.1-1.7-2.0-1.81.81.8-1.9-1.90.8-1.8-1.7-2.0-2.0-0.71.00.5
Time in familiar zone, hab. session 13.43.15.3-0.61.5-1.81.9-1.5-1.52.31.72.31.9-2.0-2.02.02.3-0.82.02.11.91.91.4-1.2-0.9
Time in novel zone, hab. session 13.93.87.81.4-1.51.8-2.52.71.3-2.3-1.5-2.3-2.01.71.7-2.0-2.30.8-2.8-1.4-1.7-1.7-2.12.8-0.3
Total zone transitions, hab. session 11.72.44.7-0.3-1.21.5-1.70.71.2-1.6-2.0-1.6-2.11.81.8-2.2-1.90.6-1.5-2.1-1.4-1.4-1.70.51.3
Total locomotion distance, hab. session 11.31.83.70.0-1.01.3-1.71.30.7-1.4-1.5-1.3-1.81.31.3-1.8-1.60.2-1.9-1.6-1.0-1.0-1.91.40.3
Locomotion velocity, hab. session 11.72.44.90.1-1.11.5-1.81.11.2-1.7-1.8-1.6-2.21.61.6-2.2-1.90.8-1.8-2.1-1.3-1.3-1.51.00.8
Time in familiar zone, hab. session 20.40.51.80.20.2-0.40.5-0.6-0.20.60.50.50.9-0.4-0.41.00.9-1.40.91.30.30.30.3-0.70.2
Time in novel zone, hab. session 20.40.42.6-0.40.4-0.1-0.30.50.1-0.4-0.0-0.4-0.80.00.0-0.9-0.81.6-0.7-0.9-0.2-0.2-0.10.9-0.3
Total zone transitions, hab. session 20.10.20.90.10.2-0.20.1-0.10.20.40.20.40.0-0.3-0.30.10.3-1.00.20.30.60.60.90.1-0.6
Total locomotion distance, hab. session 20.10.21.0-0.30.5-0.30.1-0.00.40.30.20.4-0.2-0.5-0.5-0.20.2-1.00.0-0.00.60.60.50.3-0.6
Locomotion velocity, hab. session 20.10.20.9-0.20.4-0.20.0-0.00.50.30.10.3-0.3-0.3-0.3-0.30.1-0.90.0-0.10.60.60.50.2-0.5
Novel to familiar place preference ratio2.52.67.41.3-1.31.7-1.81.21.9-1.6-1.9-1.6-2.01.71.7-1.9-1.72.7-1.0-1.5-1.4-1.4-0.90.11.4
Novelty place preference2.32.38.31.4-1.01.5-1.71.31.7-1.4-1.8-1.4-2.01.61.6-1.9-1.62.9-0.9-1.3-1.3-1.3-0.90.31.1
Time in novel zone, NPP test2.52.69.11.4-0.91.5-1.91.41.8-1.5-1.8-1.5-2.21.61.6-2.0-1.73.0-1.0-1.2-1.4-1.4-0.90.61.1
Total zone transitions, NPP test0.00.10.5-0.20.1-0.0-0.1-0.00.40.0-0.10.0-0.2-0.0-0.0-0.2-0.1-0.7-0.1-0.00.20.20.70.2-0.2
Total locomotion distance, NPP test0.10.20.7-0.50.10.1-0.50.40.1-0.2-0.4-0.2-0.70.00.0-0.7-0.5-0.5-0.7-0.50.20.2-0.40.8-0.2
Locomotion velocity, NPP test0.10.10.8-0.70.2-0.2-0.10.1-0.20.1-0.10.1-0.3-0.2-0.2-0.4-0.2-0.9-0.4-0.40.60.6-0.00.5-0.4
Intraocular pressure1.52.04.1-0.70.6-1.21.6-1.3-1.21.71.51.62.0-1.6-1.62.01.8-0.91.31.51.61.60.6-1.0-1.0
Delta distance traveled before/after self-admin0.40.41.7-1.30.6-0.60.9-1.2-0.30.40.40.30.5-0.3-0.30.40.3-0.10.8-0.20.40.40.6-1.00.6
Delta ambulatory time before/after self-admin0.20.21.2-1.1-0.20.10.5-1.00.2-0.2-0.0-0.20.30.10.10.2-0.1-0.40.3-0.6-0.1-0.1-0.1-0.90.7
Parametrial fat weight2.54.88.01.7-2.12.6-2.20.72.8-2.6-2.6-2.6-2.52.42.4-2.5-2.42.3-1.1-2.3-2.4-2.4-1.5-0.21.8
Pavlov. Cond. lever latency2.12.77.40.51.0-1.41.0-0.1-1.51.81.91.91.9-2.0-2.02.02.1-1.30.82.71.81.80.20.8-2.5
Pavlov. Cond. magazine entry latency1.62.04.00.7-1.71.8-1.50.91.4-1.5-1.9-1.5-1.52.02.0-1.5-1.50.8-1.1-1.6-1.2-1.2-0.6-0.11.5
Pavlov. Cond. change in total contacts2.02.15.2-0.7-1.01.2-1.0-0.21.4-1.3-2.0-1.4-1.62.12.1-1.7-1.61.4-0.5-2.1-1.4-1.4-0.8-0.92.3
Pavlov. Cond. index score2.02.54.90.2-1.41.7-1.50.71.6-1.7-2.0-1.8-1.82.12.1-1.9-1.91.1-1.1-2.2-1.5-1.5-0.5-0.21.9
Pavlov. Cond. latency score1.82.44.60.2-1.41.6-1.40.61.5-1.7-1.9-1.8-1.72.02.0-1.8-1.81.1-1.1-2.1-1.5-1.5-0.5-0.21.9
Pavlov. Cond. lever contacts0.80.93.2-0.6-0.50.7-0.60.20.7-1.0-1.1-1.1-1.21.11.1-1.3-1.30.8-0.6-1.8-0.7-0.70.0-0.21.3
Pavlov. Cond. magazine entry number1.92.44.9-0.11.6-1.71.7-0.8-1.11.62.11.61.8-2.2-2.21.81.8-1.21.42.01.21.20.8-0.2-1.6
Pavlov. Cond. intertrial magazine entries0.50.61.9-1.11.4-1.10.6-0.1-0.80.61.00.70.1-1.2-1.20.10.3-0.1-0.10.10.80.80.11.0-1.0
Pavlov. Cond. lever-magazine prob. diff.1.41.73.50.1-1.31.4-1.20.71.2-1.4-1.7-1.4-1.41.81.8-1.5-1.50.7-1.1-1.9-1.1-1.1-0.4-0.11.5
Pavlov. Cond. response bias1.51.94.30.0-1.31.5-1.40.81.3-1.5-1.7-1.5-1.61.81.8-1.7-1.71.0-1.4-2.1-1.0-1.0-0.30.31.3
Pavlov. Cond. lever latency0.50.73.0-0.90.8-0.20.3-1.30.6-0.0-0.4-0.1-0.80.60.6-0.7-0.41.71.1-0.6-0.4-0.40.8-1.41.0
Pavlov. Cond. magazine entry latency0.81.04.40.6-0.3-0.30.20.7-1.10.80.80.81.4-0.9-0.91.41.1-2.1-0.31.51.01.0-0.10.8-1.1
Pavlov. Cond. change in total contacts0.40.52.20.7-0.80.4-0.61.4-0.7-0.20.1-0.10.3-0.2-0.20.2-0.0-1.2-1.30.10.20.2-1.31.5-0.7
Pavlov. Cond. index score0.91.14.41.1-0.70.1-0.31.6-1.00.30.70.41.1-0.9-0.91.00.7-2.1-1.11.00.90.9-0.71.8-1.6
Pavlov. Cond. latency score0.70.93.91.1-0.80.2-0.31.5-0.80.20.50.30.9-0.7-0.70.90.5-2.0-1.10.90.70.7-0.81.6-1.2
Pavlov. Cond. lever contacts0.60.83.51.2-0.90.5-0.81.8-0.2-0.30.1-0.20.3-0.3-0.30.2-0.0-1.4-1.50.30.10.1-0.81.9-1.0
Pavlov. Cond. magazine entry number0.91.14.2-0.70.10.5-0.2-1.01.2-0.6-1.1-0.7-1.41.01.0-1.4-1.02.00.5-1.5-1.0-1.00.1-1.41.5
Pavlov. Cond. intertrial magazine entries2.33.09.5-1.30.30.6-0.4-1.51.9-1.2-1.7-1.4-2.31.71.7-2.3-1.83.10.6-2.4-1.8-1.80.5-1.82.7
Pavlov. Cond. lever-magazine prob. diff.1.11.45.81.0-0.5-0.2-0.01.5-1.20.61.00.71.3-1.2-1.21.30.9-2.4-1.01.31.21.2-0.61.8-1.8
Pavlov. Cond. response bias0.81.03.81.2-0.70.2-0.51.8-0.80.10.50.30.8-0.7-0.70.80.5-1.9-1.40.80.70.7-0.61.9-1.5
Time in closed arm before self-admin0.80.93.41.6-1.61.3-1.01.20.5-0.7-0.3-0.70.20.30.30.2-0.1-0.4-1.20.2-0.2-0.2-1.81.1-1.1
Time in closed arm after self-admin1.91.93.3-0.2-1.01.3-1.40.21.1-1.7-1.6-1.7-1.81.71.7-1.8-1.80.7-1.2-1.8-1.2-1.2-1.70.51.1
Time in open arm before self-admin1.51.710.6-3.32.3-1.91.4-2.0-1.00.90.70.8-0.3-0.5-0.5-0.4-0.00.61.0-0.70.80.81.7-0.71.0
Time in open arm after self-admin0.50.61.40.90.3-0.50.40.8-0.40.70.80.81.0-0.9-0.91.01.0-0.30.11.20.60.61.00.4-1.1
Bone: periosteal estimation1.53.04.31.8-1.92.1-2.01.91.9-2.1-1.7-2.0-1.71.81.8-1.8-1.80.9-1.8-1.6-1.8-1.8-1.11.00.4
Bone: periosteal perimeter0.50.82.61.5-0.80.9-1.21.60.8-0.9-0.5-0.8-0.80.60.6-0.7-0.70.1-1.2-0.3-0.6-0.6-0.41.3-0.6
Bone: post-yield work0.30.52.41.2-0.50.10.2-0.1-0.30.40.10.41.0-0.5-0.51.10.9-1.60.71.30.10.10.2-0.7-0.2
Progressive ratio test 1 active lever presses0.10.10.70.2-0.50.30.4-0.20.10.30.00.30.70.10.10.60.5-0.60.2-0.30.30.3-0.1-0.8-0.2
Progressive ratio test 1 breakpoint0.10.10.50.2-0.50.30.40.00.20.2-0.00.20.70.10.10.50.4-0.60.1-0.20.20.2-0.1-0.7-0.3
Progressive ratio test 1 inactive lever presses1.01.12.90.60.3-0.61.4-0.3-0.40.91.30.91.7-1.2-1.21.61.3-1.41.20.80.70.71.0-1.1-0.9
Progressive ratio test 2 active lever presses0.10.10.7-0.1-0.50.30.1-0.0-0.1-0.0-0.20.00.30.20.20.20.2-0.9-0.2-0.40.00.0-0.6-0.4-0.1
Progressive ratio test 2 breakpoint0.10.11.0-0.1-0.50.30.20.2-0.10.0-0.00.10.50.10.10.30.2-1.0-0.2-0.40.00.0-0.6-0.3-0.2
Progressive ratio test 2 inactive lever presses0.40.54.40.7-0.60.10.60.20.00.20.60.31.3-0.5-0.51.20.7-2.10.10.4-0.0-0.0-0.3-0.4-0.7
Incentive Sensitization - Responses0.10.10.80.1-0.50.3-0.10.4-0.4-0.1-0.1-0.10.20.10.10.20.0-0.9-0.4-0.20.10.1-0.9-0.0-0.2
Incentive Sensitization - Breakpoint0.10.10.90.0-0.60.3-0.10.4-0.4-0.2-0.1-0.20.20.10.10.1-0.0-0.8-0.4-0.30.10.1-0.90.1-0.2
Sum of active levers in priming session hrs 5-61.00.92.60.6-1.01.1-0.60.11.6-1.1-1.1-1.1-0.71.11.1-0.8-1.00.1-0.0-1.1-1.1-1.10.1-0.91.5
Progressive ratio0.30.31.2-0.6-0.50.5-0.5-0.2-0.3-0.6-0.4-0.5-0.50.40.4-0.6-0.70.2-0.9-1.00.60.6-1.10.60.0
Food seeking constrained by brief footshock1.31.65.4-1.51.9-1.51.4-2.1-0.61.20.81.20.3-0.8-0.80.40.80.72.00.61.11.12.3-1.60.7
Seeking ratio, punishment vs. effort0.80.94.4-0.11.1-1.01.0-1.00.11.00.60.90.5-0.5-0.50.70.90.21.81.10.00.02.1-1.50.5
Retroperitoneal fat weight0.41.38.70.4-0.60.70.6-1.71.6-0.4-0.7-0.50.10.80.80.1-0.10.81.7-0.6-1.0-1.01.5-3.01.6
Reaction time number correct1.42.05.7-2.22.4-2.11.1-0.8-2.01.51.51.50.3-1.4-1.40.40.8-0.10.51.01.81.80.51.0-1.4
Reaction time mean minus median0.00.00.30.20.2-0.1-0.1-0.10.1-0.10.2-0.10.0-0.0-0.00.1-0.0-0.20.10.6-0.0-0.00.30.5-0.4
Reaction time mean minus median AUC0.10.10.60.30.2-0.2-0.10.1-0.10.10.30.10.2-0.2-0.20.30.2-0.4-0.10.80.30.30.10.7-0.6
Reaction time num false alarms1.11.54.1-1.41.7-1.51.7-2.0-0.51.21.11.10.7-1.1-1.10.70.9-0.22.00.40.20.21.4-1.80.7
Reaction time num false alarms AUC0.71.03.0-1.41.6-1.21.3-1.7-0.30.80.70.80.2-0.7-0.70.20.50.31.70.10.00.01.1-1.50.8
Reaction time trials correct on left1.42.05.7-2.22.4-2.11.1-0.8-2.01.51.51.50.3-1.4-1.40.40.8-0.10.51.01.81.80.51.0-1.4
Reaction time trials on left1.31.85.7-2.22.4-2.11.0-0.8-1.91.41.41.50.2-1.4-1.40.30.8-0.00.50.91.71.70.41.0-1.4
Reaction time mean1.82.47.62.8-2.72.3-1.82.51.5-1.7-1.1-1.7-0.31.21.2-0.4-1.1-0.2-2.1-0.7-1.1-1.1-1.51.3-0.3
Reaction time mean AUC1.92.67.62.4-2.82.3-1.82.31.6-1.9-1.4-1.8-0.51.51.5-0.6-1.30.1-2.0-1.0-1.3-1.3-1.61.00.2
Median of all reaction times3.04.112.93.2-3.63.0-2.23.11.9-2.2-1.6-2.2-0.41.71.7-0.6-1.5-0.0-2.6-1.5-1.4-1.4-2.01.30.1
Reaction time omissions0.81.14.00.4-0.51.0-1.0-0.12.0-1.2-1.2-1.2-1.41.31.3-1.3-1.20.9-0.2-0.9-1.3-1.3-0.4-0.21.1
Reaction time false alarm rate0.50.63.80.10.00.20.4-1.11.0-0.2-0.4-0.3-0.20.30.3-0.2-0.20.51.2-0.6-1.1-1.10.6-1.91.6
Reaction time premature initiation rate0.40.62.10.40.2-0.40.20.7-0.40.50.80.60.6-0.9-0.90.60.6-0.8-0.30.61.01.01.51.0-1.3
Reaction time premature initiations1.52.24.5-0.81.6-1.70.90.2-1.51.51.71.60.9-1.8-1.80.91.2-1.00.11.32.02.01.81.4-2.1
Std. dev. reaction times0.50.82.71.6-1.31.2-1.11.01.2-1.1-0.6-1.1-0.30.80.8-0.2-0.6-0.2-0.80.1-1.0-1.0-0.40.70.1
Reaction time trials completed1.31.85.7-2.22.4-2.11.0-0.8-1.91.41.41.50.2-1.4-1.40.30.8-0.00.50.91.71.70.41.0-1.4
Reaction time trials AUC1.11.64.8-1.92.2-1.90.9-0.6-1.81.31.41.40.2-1.3-1.30.30.7-0.00.40.91.71.70.41.1-1.4
Run reversals in cocaine runway, females0.40.31.6-0.8-0.70.5-0.1-0.9-0.3-0.3-0.7-0.3-0.20.60.6-0.3-0.3-0.8-0.2-0.80.10.1-1.3-0.70.7
Run reversals in cocaine runway, males0.30.30.70.6-0.50.5-0.40.50.8-0.5-0.6-0.6-0.40.80.8-0.4-0.50.6-0.1-0.4-0.7-0.70.1-0.30.8
Latency to leave start box in cocaine runway0.70.73.1-1.81.1-1.01.3-1.4-1.00.70.60.70.5-0.5-0.50.30.30.10.8-0.60.80.80.7-1.00.4
Latency to leave start box in cocaine runway, F0.70.72.8-1.71.0-1.01.2-1.7-0.70.60.50.60.5-0.4-0.40.40.4-0.11.0-0.40.60.61.2-1.10.4
Latency to leave start box in cocaine runway, M0.20.21.0-0.20.1-0.20.10.4-0.90.20.20.20.1-0.2-0.20.0-0.00.1-0.5-0.20.70.7-1.00.5-0.4
Std. dev. time between licks in bursts1.51.87.4-2.72.5-2.11.7-2.1-0.91.01.31.00.3-1.0-1.00.30.40.61.60.30.60.61.5-0.80.5
Total sessions with >9 infusions0.10.10.5-0.2-0.70.5-0.10.30.4-0.3-0.4-0.20.20.40.40.0-0.20.1-0.7-0.7-0.0-0.0-0.10.1-0.2
Short access day 1 total inactive lever presses0.40.52.11.1-1.20.60.50.10.00.20.10.11.30.00.01.20.7-0.90.50.20.10.1-0.1-1.50.1
Short access day 10 total inactive lever presses0.60.65.22.3-1.20.9-0.41.30.4-0.30.1-0.30.7-0.2-0.20.70.3-1.0-0.40.5-0.6-0.6-0.30.3-0.8
Short access day 1 total infusions0.60.61.8-0.20.4-0.71.2-0.6-0.10.70.80.71.3-0.7-0.71.31.0-0.81.10.70.40.40.5-1.3-0.3
Short access day 10 total infusions0.10.20.50.6-0.70.5-0.20.40.6-0.1-0.3-0.10.30.40.40.20.2-0.5-0.3-0.0-0.5-0.50.2-0.1-0.5
Short access total infusions0.40.41.4-0.50.0-0.41.0-0.70.10.50.50.51.2-0.4-0.41.10.8-0.80.70.20.10.10.7-1.2-0.2
Short access day 1 locomotion0.60.61.70.8-1.21.1-0.61.11.1-0.6-0.7-0.6-0.30.70.7-0.5-0.50.2-1.1-1.3-0.6-0.6-0.60.3-0.1
Short access day 10 total locomotion0.91.03.61.3-0.90.10.31.0-0.10.80.90.91.6-0.8-0.81.51.3-1.9-0.31.00.60.6-0.20.5-1.8
Short access total locomotion0.40.52.70.2-0.80.10.50.20.10.70.40.71.3-0.4-0.41.21.0-1.7-0.10.20.20.20.2-0.3-0.7
One hour access (0.3 mA shock)0.80.96.21.3-1.40.60.20.7-0.40.30.50.41.6-0.3-0.31.51.0-2.5-0.30.60.40.4-1.0-0.1-1.2
Compulsive drug intake0.20.21.20.2-1.10.7-0.30.10.0-0.3-0.1-0.30.40.10.10.30.0-0.8-0.8-0.3-0.0-0.0-1.10.5-0.5
One hour access (shock baseline)0.20.21.11.1-0.50.30.00.60.6-0.00.10.00.50.10.10.50.3-0.90.10.3-0.6-0.6-0.1-0.3-0.4
Social response proportion0.50.64.80.30.30.2-0.3-0.10.9-0.4-0.5-0.5-1.00.60.6-1.0-0.72.20.3-0.6-0.7-0.70.9-0.40.6
Social responses0.40.64.90.8-0.10.5-0.80.50.4-0.5-0.6-0.5-1.10.40.4-1.1-0.72.2-0.3-0.6-0.5-0.50.20.30.2
Social time0.10.20.90.60.6-0.4-0.00.9-0.10.20.50.2-0.0-0.4-0.40.00.00.3-0.20.40.20.20.20.8-0.4
Soleus weight0.10.21.4-0.61.2-0.7-0.1-0.4-0.00.1-0.00.0-0.9-0.1-0.1-0.7-0.30.90.30.3-0.1-0.10.70.4-0.0
Bone: stiffness0.40.63.61.9-1.01.0-0.70.71.6-0.6-0.7-0.7-0.20.70.7-0.2-0.2-0.10.00.2-0.9-0.90.1-0.30.3
Tibialis anterior weight0.20.51.9-0.90.9-0.70.8-1.4-0.10.80.10.70.1-0.3-0.30.10.60.01.30.20.40.41.1-1.30.3
Time to tail flick, vehicle, before self-admin0.10.10.9-0.4-0.0-0.1-0.10.1-0.6-0.10.2-0.0-0.0-0.1-0.1-0.0-0.1-0.7-0.4-0.0-0.0-0.0-1.00.7-0.3
Time to tail flick, vehicle, after self-admin0.20.31.30.2-0.30.4-0.70.60.3-0.4-0.2-0.4-0.40.20.2-0.3-0.3-0.2-0.80.0-0.7-0.7-0.61.2-0.6
Time to tail flick, test, before self-admin1.61.65.1-0.1-1.51.6-1.40.11.2-1.4-1.5-1.4-1.21.51.5-1.3-1.20.3-1.2-1.3-1.2-1.2-2.30.30.9
Time to tail flick, test, after self-admin5.05.27.3-1.51.9-2.42.7-2.1-2.32.62.42.62.6-2.3-2.32.62.7-2.02.42.02.32.32.6-1.6-1.1
Delta time to tail flick, vehicle, before/after SA0.40.41.30.40.1-0.40.5-0.4-0.20.70.60.71.0-0.6-0.61.01.0-0.50.71.10.20.20.8-0.5-0.7
Delta time to tail flick, test, before/after SA8.47.613.4-1.22.7-3.13.2-1.4-2.83.23.23.23.1-3.1-3.13.13.0-1.62.52.63.03.03.7-1.0-1.9
Tibia length1.95.310.52.8-3.03.1-2.42.23.2-2.7-2.5-2.7-1.82.62.6-1.9-2.21.2-1.9-2.1-2.4-2.4-0.50.41.3
Ambulatory time before self-admin0.20.21.51.1-0.30.30.00.20.70.1-0.20.00.20.10.10.30.30.00.50.4-0.4-0.41.2-0.7-0.1
Ambulatory time after self-admin0.60.74.4-0.8-0.20.01.0-1.50.60.0-0.1-0.10.70.10.10.60.20.31.1-0.5-0.4-0.41.7-2.11.1
Bone: tissue strength0.40.41.50.2-0.40.4-0.2-0.50.7-0.3-0.8-0.4-0.30.70.7-0.3-0.3-0.00.5-0.2-0.8-0.80.4-1.11.2
Total heroin consumption0.30.42.71.6-0.40.4-0.30.80.90.10.30.10.3-0.4-0.40.40.4-0.60.10.8-0.8-0.80.60.3-0.9
Bone: trabecular number0.20.30.9-0.50.3-0.0-0.1-0.80.3-0.1-0.6-0.2-0.70.60.6-0.6-0.40.50.5-0.2-0.5-0.50.1-0.61.0
Bone: trabecular spacing0.50.73.71.0-1.91.3-0.51.10.4-0.8-0.4-0.80.40.30.30.2-0.4-0.4-1.1-0.9-0.7-0.7-1.00.1-0.1
Bone: trabecular thickness0.30.30.80.9-0.30.4-0.80.40.5-0.5-0.7-0.5-0.50.70.7-0.4-0.4-0.5-0.10.6-0.7-0.7-0.50.30.5
Bone: trabecular tissue density1.31.86.40.8-1.0-0.00.71.0-0.90.61.50.72.4-1.4-1.42.11.3-2.5-0.80.81.31.30.01.0-2.1
Water consumed over 24 hours0.50.62.2-0.60.8-0.90.6-0.3-1.50.70.90.70.7-1.1-1.10.70.6-0.80.20.80.60.6-0.00.5-0.7
Number of responses in last shaping day3.33.46.90.7-1.62.0-1.70.92.2-2.1-2.1-2.1-2.12.12.1-2.2-2.21.4-1.4-2.6-2.0-2.0-1.3-0.01.5