Josd1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Josd1 0.17 0.1 7.2e-03 0.06 0.05 0 0.04 1.3e-02 2.7e-02 3.1e-01 4.4e-02
2 PL gene expression Josd1 0.22 0.08 0.0e+00 0.23 0.24 0.25 0.25 6.0e-25 6.6e-26 3.8e-27 5.5e-27
3 BLA gene expression Josd1 0.26 0.09 3.4e-14 0.19 0.22 0.23 0.23 1.4e-10 2.7e-12 1.4e-12 9.5e-13
4 Liver alternative TSS XM_039079268.1 0.03 0.02 6.3e-03 0.02 0 0.01 0 4.6e-03 1.4e-01 6.5e-02 8.9e-02
5 PL isoform ratio XM_039079268.1 0.03 0.02 2.4e-03 0.02 0.01 0.02 0.02 1.2e-03 8.8e-03 5.2e-03 5.2e-03
6 PL isoform ratio NM_001025009.1 0.03 0.02 1.8e-03 0.02 0.02 0.01 0.02 2.0e-03 6.7e-03 7.8e-03 5.7e-03
7 NAcc gene expression Josd1 0.04 0.03 1.1e-03 0.01 0.02 0.02 0.01 6.8e-03 4.4e-03 4.8e-03 6.1e-03
8 NAcc alternative TSS XM_039079268.1 0.12 0.05 2.3e-11 0.1 0.1 0.11 0.11 4.0e-11 6.8e-12 4.9e-13 2.5e-12
9 Adipose mRNA stability Josd1 0.03 0.02 2.8e-03 0.02 0.02 0.02 0.02 1.7e-03 1.3e-03 3.1e-03 2.5e-03
10 NAcc alternative TSS NM_001025009.1 0.11 0.05 4.5e-10 0.08 0.1 0.1 0.09 1.2e-09 3.7e-11 4.4e-11 5.4e-11
11 pVTA alternative TSS NM_001025009.1 0.08 0.05 4.2e-03 0 0.03 0.02 0.01 3.0e-01 1.6e-02 4.1e-02 1.2e-01
12 pVTA alternative TSS XM_039079268.1 0.1 0.05 2.2e-03 0.01 0.04 0.03 0.02 1.1e-01 7.4e-03 2.6e-02 5.4e-02
13 PL alternative TSS NM_001025009.1 0.42 0.16 0.0e+00 0.2 0.2 0.19 0.2 3.4e-21 3.1e-21 4.7e-20 1.8e-21
14 Brain mRNA stability Josd1 0.08 0.04 8.3e-06 0.06 0.08 0.06 0.03 5.5e-06 1.3e-07 1.5e-06 2.2e-03
15 PL alternative TSS XM_039079268.1 0.36 0.13 0.0e+00 0.21 0.2 0.19 0.2 1.7e-22 7.5e-22 8.4e-21 3.6e-22
16 Brain gene expression Josd1 0.08 0.04 4.9e-07 0.02 0.05 0.05 0.05 6.3e-03 2.0e-05 3.4e-05 2.4e-05
17 PL mRNA stability Josd1 0.05 0.03 3.1e-05 0.02 0.04 0.04 0.04 6.2e-03 2.3e-05 9.0e-06 5.6e-05
18 OFC gene expression Josd1 0.21 0.11 3.0e-03 0.12 0.03 0.05 0.07 8.7e-04 6.2e-02 2.8e-02 1.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density0.00.00.2-0.10.1-0.10.20.2-0.2-0.30.0-0.00.40.2-0.2-0.00.40.00.10.10.4
Area under the delay curve2.12.25.71.82.4-2.22.42.4-2.4-1.00.22.00.00.6-0.5-0.31.3-0.5-1.1-0.4-0.4
BMI with tail0.00.10.8-0.4-0.50.90.10.1-0.10.90.2-0.40.1-0.1-0.10.2-0.40.10.0-0.20.1
BMI without tail0.40.92.30.60.6-0.61.51.5-1.5-0.31.4-0.21.41.0-1.00.90.40.5-0.70.10.7
Body weight1.14.612.9-3.6-3.43.3-2.6-2.62.62.6-1.5-1.7-1.5-1.81.5-0.5-1.6-0.71.8-0.4-0.4
Weight adjusted by age0.30.30.9-0.3-0.7-0.1-0.7-0.70.7-0.3-0.2-1.00.10.1-0.10.5-0.70.6-0.00.80.6
Bone surface0.10.10.6-0.70.1-0.10.40.4-0.40.2-0.80.5-0.4-0.20.1-0.40.3-0.5-0.1-0.2-0.3
Bone volume0.00.10.2-0.40.1-0.10.30.3-0.3-0.2-0.2-0.00.20.3-0.30.0-0.1-0.0-0.20.30.3
Breakpoint value in progressive ratio session0.30.31.20.20.5-0.51.11.1-1.1-0.00.50.40.50.3-0.3-0.00.5-0.1-0.2-0.4-0.3
Number of licking bursts0.70.81.70.91.2-1.21.31.3-1.3-1.30.70.50.60.9-0.80.40.20.2-0.90.50.5
Context. condit. distance diff. score3.34.08.7-2.6-2.82.8-2.8-2.82.81.1-0.5-3.0-0.1-0.30.10.9-2.91.20.61.51.2
Locomotion velocity, session 11.01.03.1-0.7-0.00.1-0.5-0.50.50.8-1.51.3-1.8-1.41.3-1.00.8-1.00.7-0.9-1.4
Locomotion distance, session 12.32.98.02.02.8-2.72.52.5-2.5-1.40.22.4-0.00.7-0.7-0.21.5-0.3-1.5-0.1-0.5
Locomotion velocity, session 20.10.20.60.10.30.3-0.1-0.10.10.8-0.40.6-0.7-0.50.3-0.30.2-0.4-0.1-0.5-0.6
Locomotion distance, session 22.53.510.22.12.8-2.52.42.4-2.4-0.7-0.13.2-0.5-0.00.1-1.22.6-1.4-0.7-1.5-1.7
Locomotion velocity, session 31.41.65.0-1.0-1.20.4-1.1-1.11.1-0.40.4-2.10.60.8-0.91.4-2.21.5-0.71.81.6
Locomotion distance, session 32.93.26.00.91.0-1.71.41.4-1.4-2.31.7-0.81.62.2-2.22.1-1.52.0-2.32.41.9
Stereotopy head waving bouts, day 31.31.62.7-1.1-1.21.4-1.0-1.01.01.6-1.50.3-1.5-1.61.6-1.30.4-1.31.5-1.3-1.1
Stereotopy head waving duration, day 33.54.26.9-2.2-2.42.6-2.4-2.42.42.6-2.1-0.4-2.0-2.42.3-1.4-0.0-1.32.4-1.4-1.2
Locomotion velocity, session 70.40.41.2-1.1-0.51.1-0.7-0.70.70.2-0.8-0.7-0.6-0.50.40.0-0.90.00.40.30.1
Locomotion distance, session 70.60.71.8-0.60.10.5-0.6-0.60.60.2-1.30.7-1.2-1.11.2-1.00.5-1.01.0-0.7-1.2
Stereotopy head waving bouts, day 72.02.35.7-1.6-2.42.4-2.1-2.12.11.4-0.8-2.0-0.6-0.80.60.5-1.70.70.80.71.0
Stereotopy head waving duration, day 71.62.05.8-0.8-2.01.9-1.7-1.71.70.80.2-2.40.40.0-0.21.2-1.91.40.21.41.7
Locomotion velocity, session 81.62.03.9-1.8-1.62.0-1.7-1.71.71.7-1.6-0.2-1.7-1.61.4-0.7-0.5-0.71.1-0.5-1.0
Locomotion distance, session 80.20.30.9-0.4-0.60.6-0.9-0.90.90.2-0.1-0.90.20.1-0.10.3-0.80.5-0.00.60.4
Degree of sensitization distance6.16.111.1-1.6-1.72.7-2.6-2.62.62.6-2.50.5-2.4-3.13.2-2.61.3-2.53.3-2.7-2.4
Degree of sensitization stereotypy1.41.53.9-0.9-1.61.5-1.4-1.41.40.5-0.0-2.00.10.1-0.31.2-1.81.4-0.11.41.6
Conditioned locomotion0.40.51.8-0.4-0.80.9-1.3-1.31.30.4-0.7-0.5-0.4-0.60.6-0.4-0.2-0.30.7-0.00.1
Cocaine response after cond. corrected0.70.81.6-0.3-0.30.3-0.5-0.50.51.0-1.00.8-1.1-1.00.9-1.30.7-1.20.6-1.3-1.0
Cocaine response after cond. not corrected0.30.30.9-0.1-0.20.2-0.2-0.20.20.8-0.50.5-0.6-0.60.5-0.80.5-0.80.3-1.0-0.7
Cocaine response before conditioning0.81.01.80.80.5-0.41.01.0-1.0-0.81.2-0.71.31.2-1.21.2-0.61.1-1.00.81.1
Saline control response0.60.82.40.2-1.00.5-1.0-1.01.0-0.20.4-1.61.00.7-0.80.7-1.01.1-0.30.91.0
Bone: connectivity density0.10.10.4-0.7-0.40.4-0.4-0.40.40.2-0.3-0.1-0.2-0.40.4-0.20.3-0.10.6-0.2-0.1
Bone: cortical apparent density1.41.94.00.40.3-0.90.50.5-0.5-1.71.9-1.31.51.6-1.51.9-1.51.8-1.32.01.3
Bone: cortical area0.50.81.6-1.2-0.60.9-0.3-0.30.31.3-1.00.5-1.2-1.11.0-1.00.2-1.20.7-1.0-1.0
Bone: cortical porosity1.81.93.9-0.9-1.11.8-1.1-1.11.12.0-1.90.3-1.3-1.51.4-1.80.7-1.61.3-1.7-1.2
Bone: cortical porosity3.03.26.9-1.2-1.42.2-1.4-1.41.42.6-2.40.6-1.9-2.01.8-2.30.8-2.11.6-2.3-1.7
Bone: cortical thickness0.30.51.80.40.9-0.51.31.3-1.3-0.10.51.0-0.00.3-0.4-0.20.2-0.5-0.7-0.4-0.3
Bone: cortical thickness0.60.72.50.81.5-1.21.11.1-1.1-0.30.41.6-0.30.2-0.2-0.40.7-0.7-0.7-0.6-0.6
Bone: cortical tissue density1.31.73.80.30.2-0.90.40.4-0.4-1.71.8-1.31.31.5-1.41.8-1.51.8-1.21.91.2
Condit. Reinf. active minus inactive responses0.00.00.20.3-0.0-0.4-0.0-0.00.0-0.40.2-0.10.10.2-0.1-0.1-0.20.00.00.3-0.3
Condit. Reinf. active-inactive response ratio0.30.31.1-0.3-0.50.1-0.5-0.50.5-0.30.1-0.90.30.4-0.40.4-1.00.6-0.20.80.2
Condit. Reinf. active responses0.60.72.21.30.4-1.10.40.4-0.4-1.21.5-0.51.31.0-0.80.7-0.10.7-0.30.80.5
Condit. Reinf. inactive responses1.31.55.31.60.7-1.30.80.8-0.8-1.62.3-0.61.91.4-1.11.20.21.0-0.41.01.3
Incentive salience index mean0.10.20.70.80.2-0.70.30.3-0.3-0.80.7-0.00.50.3-0.20.10.10.10.10.3-0.1
Condit. Reinf. lever presses0.30.31.61.20.3-0.70.50.5-0.5-0.91.2-0.00.80.4-0.20.20.40.10.20.20.2
Condit. Reinf. active minus inactive responses0.81.03.2-0.40.7-0.40.40.4-0.40.6-1.41.7-1.4-0.90.9-1.20.9-1.10.2-1.2-1.8
Condit. Reinf. active-inactive response ratio1.11.23.1-0.5-0.10.3-0.3-0.30.31.1-1.51.3-1.5-1.31.3-1.40.8-1.40.8-1.2-1.8
Condit. Reinf. active responses0.81.13.2-0.80.40.00.10.1-0.11.0-1.81.4-1.7-1.10.9-1.20.4-1.10.2-1.2-1.7
Condit. Reinf. inactive responses0.20.21.0-0.50.6-0.10.40.4-0.40.2-1.00.7-0.9-0.30.1-0.3-0.4-0.3-0.5-0.4-0.6
Condit. Reinf. lever presses0.20.31.30.51.1-0.90.60.6-0.6-0.5-0.20.80.20.1-0.0-0.30.8-0.1-0.1-0.1-0.4
Condit. Reinf. lever reinforcers received0.81.23.3-0.80.30.1-0.2-0.20.21.1-1.81.4-1.7-1.21.1-1.30.6-1.20.5-1.4-1.8
Conditioned reinforcement - actives0.60.62.30.41.3-1.20.90.9-0.9-0.4-0.61.5-0.60.2-0.2-0.80.4-0.6-0.9-0.4-0.5
Conditioned reinforcement - inactives0.70.82.80.81.3-1.01.21.2-1.2-0.50.11.7-0.20.00.1-0.81.3-0.8-0.1-0.7-0.8
Conditioned locomotion1.11.33.70.0-0.00.2-0.1-0.10.11.3-1.41.7-1.5-1.11.0-1.90.9-1.70.4-1.6-1.5
Patch foraging indifference point 0 sec0.30.41.3-0.1-0.50.6-0.9-0.90.90.1-0.1-0.10.2-0.40.6-0.70.9-0.51.1-0.7-0.7
Patch foraging indifference point AUC0.80.93.51.01.5-1.30.90.9-0.9-0.8-0.41.9-0.7-0.00.0-0.90.8-0.9-0.6-0.6-0.8
Delay disc. indifference point, 0s delay0.50.52.00.2-0.30.50.00.0-0.01.2-0.30.6-0.4-0.70.6-0.90.7-0.90.6-1.4-1.2
Delay disc. indifference point, 16s delay2.52.56.51.92.5-2.62.32.3-2.3-1.2-0.12.30.00.6-0.6-0.51.6-0.7-1.2-0.5-0.5
Delay disc. indifference point, 2s delay3.03.39.92.22.7-2.13.23.2-3.2-0.40.52.4-0.00.7-0.9-0.11.1-0.4-1.8-0.8-0.7
Delay disc. indifference point, 24s delay0.40.41.4-0.20.7-0.90.50.5-0.5-0.6-0.71.2-0.9-0.40.4-0.30.5-0.5-0.1-0.1-0.5
Delay disc. indifference point, 4s delay1.21.33.51.41.5-1.31.61.6-1.6-0.1-0.31.9-0.4-0.10.1-0.71.4-0.8-0.4-1.0-1.0
Delay disc. indifference point, 8s delay1.61.64.21.52.1-2.02.02.0-2.0-1.40.41.60.30.7-0.5-0.21.2-0.4-0.80.0-0.1
Indifference point function ln k1.21.74.7-1.9-2.21.9-1.6-1.61.61.2-0.1-2.10.2-0.20.10.8-1.60.80.50.60.5
Indifference point function log k1.21.74.7-1.9-2.21.9-1.6-1.61.61.2-0.1-2.10.2-0.20.10.8-1.60.80.50.60.5
Patch foraging total patch changes 0 sec0.10.21.10.4-0.10.1-0.5-0.50.5-0.20.30.10.5-0.10.3-0.51.1-0.40.8-0.6-0.5
Patch foraging total patch changes 12 sec0.70.92.30.50.10.3-0.3-0.30.30.6-0.81.2-1.0-0.90.9-1.51.1-1.50.7-1.5-1.4
Patch foraging total patch changes 18 sec1.41.84.6-0.00.50.10.00.0-0.00.6-1.21.9-1.2-1.31.5-1.92.1-1.91.3-1.9-2.2
Patch foraging total patch changes 24 sec0.30.41.20.91.1-0.30.60.6-0.6-0.80.50.90.10.10.1-0.30.9-0.30.1-0.5-0.8
Patch foraging total patch changes 6 sec0.60.93.40.70.8-0.30.30.3-0.3-0.2-0.31.7-0.6-0.60.8-1.31.8-1.30.7-1.4-1.3
Patch foraging time to switch 0 sec0.30.51.40.30.10.80.20.2-0.21.2-0.80.6-0.6-0.80.7-0.80.8-0.90.6-1.1-0.7
Patch foraging water rate 0 sec0.30.41.3-0.8-0.8-0.1-1.2-1.21.2-0.60.4-0.60.3-0.20.40.00.30.01.00.10.1
Patch foraging water rate 12 sec0.40.72.70.1-0.4-0.1-0.1-0.10.1-0.71.6-1.21.40.9-0.81.2-0.41.1-0.30.80.7
Patch foraging water rate 18 sec0.10.20.5-0.5-0.7-0.3-0.5-0.50.5-0.50.5-0.40.3-0.10.30.30.40.20.70.2-0.1
Patch foraging water rate 24 sec1.21.65.0-1.9-2.21.4-2.0-2.02.00.9-0.2-1.6-0.0-0.60.60.2-0.70.41.20.30.2
Patch foraging water rate 6 sec0.71.12.5-0.2-0.5-0.8-0.1-0.10.1-1.51.2-1.51.61.3-1.21.1-0.81.2-0.51.41.2
Seeking ratio, delayed vs. immediate footshock0.60.61.41.20.9-1.10.90.9-0.9-0.90.5-0.10.90.7-0.60.60.30.7-0.50.90.9
Distance traveled before self-admin0.91.03.41.51.8-0.91.01.0-1.0-0.2-0.21.8-0.2-0.00.0-0.91.5-1.0-0.4-1.0-0.6
Distance traveled after self-admin2.32.65.9-0.8-0.30.3-0.7-0.70.71.3-1.91.6-1.7-1.81.9-2.41.9-2.41.8-2.2-2.0
Extensor digitorum longus weight0.72.65.32.21.8-2.02.32.3-2.3-1.31.80.61.91.6-1.50.81.10.7-1.30.40.9
Bone: elastic displacement0.30.40.8-0.9-0.70.7-0.9-0.90.90.4-0.7-0.3-0.5-0.60.6-0.2-0.0-0.20.6-0.0-0.1
Bone: elastic work2.83.66.0-2.0-1.51.8-1.9-1.91.92.3-2.50.5-2.0-2.32.2-2.00.8-2.02.0-1.8-1.5
Bone: endosteal estimation1.73.76.9-2.4-1.71.9-2.2-2.22.22.2-2.60.2-2.1-2.22.1-1.80.3-1.61.9-1.4-1.7
Bone: endosteal perimeter1.53.16.4-2.5-2.02.2-1.9-1.91.92.2-2.5-0.4-1.9-1.91.7-1.4-0.3-1.21.6-1.0-1.2
Epididymis fat weight1.53.59.0-3.0-2.92.9-2.4-2.42.41.9-1.3-2.1-1.1-0.70.30.1-3.00.40.20.50.1
Delta time in closed arm before/after self-admin0.20.20.80.10.10.5-0.3-0.30.30.4-0.80.5-0.9-0.40.2-0.8-0.4-0.7-0.1-0.3-0.4
Delta time in open arm before/after self-admin0.10.10.40.40.3-0.60.50.5-0.5-0.20.60.20.40.2-0.20.10.6-0.2-0.0-0.2-0.1
Diff in mean of infusions in LGA sessions0.20.20.5-0.30.4-0.50.70.7-0.7-0.10.10.7-0.4-0.20.3-0.20.3-0.40.1-0.4-0.6
Delay discount exponential model param2.22.35.9-1.8-2.42.3-2.4-2.42.41.1-0.2-2.0-0.1-0.70.70.2-1.20.41.30.30.3
Extinction: sum of active levers before priming1.41.44.61.11.7-1.62.22.2-2.2-0.50.21.40.00.6-0.70.00.5-0.2-1.2-0.2-0.2
Active lever presses in extinction session 60.20.20.40.1-0.00.10.20.2-0.20.5-0.30.5-0.5-0.40.4-0.40.3-0.60.3-0.6-0.6
Bone: final force1.42.35.3-1.8-0.50.9-0.6-0.60.61.8-2.31.3-2.1-1.91.7-1.90.9-2.01.2-1.7-1.7
Bone: final moment1.72.86.0-1.9-0.71.1-0.9-0.90.92.0-2.41.3-2.3-2.12.0-2.11.0-2.11.5-1.8-1.9
Food consumed during 24 hour testing period1.01.22.6-1.1-0.71.0-0.5-0.50.51.6-1.50.7-1.4-1.21.0-1.30.2-1.40.7-1.2-1.5
Glucose0.20.31.1-0.8-0.91.0-0.2-0.20.20.60.4-0.30.0-0.50.6-0.10.4-0.61.1-0.7-0.5
Heart weight1.41.95.7-1.9-2.32.4-1.8-1.81.81.30.2-1.3-0.4-1.21.30.1-0.40.11.9-0.3-0.2
Delay discount hyperbolic model param2.32.56.4-1.9-2.52.3-2.5-2.52.51.0-0.2-2.1-0.1-0.60.60.3-1.30.51.30.50.5
Intermittent access intake day 1-15 change0.40.40.90.40.5-0.80.60.6-0.6-1.00.60.10.60.9-0.80.30.00.2-0.80.40.7
Intermittent access intake escalation0.50.51.00.50.6-0.90.90.9-0.9-1.00.80.10.81.0-1.00.40.00.2-1.00.40.7
Intermittent access intake escalation 20.20.20.60.20.3-0.40.60.6-0.6-0.60.80.00.60.6-0.60.30.10.2-0.40.20.3
Intermitt. access day 1 inactive lever presses1.41.52.8-0.9-0.40.5-0.8-0.80.81.0-1.50.8-1.1-1.51.6-1.61.4-1.51.7-1.5-1.6
Intermitt. access day 15 inactive lever presses0.70.81.5-0.9-0.10.3-0.6-0.60.60.5-1.11.0-1.2-1.01.0-1.10.7-1.10.7-0.8-1.1
Intermitt. access escalation Index0.60.51.11.00.8-0.61.01.0-1.0-0.51.00.20.70.7-0.70.80.20.5-0.70.40.4
Intermittent access day 1 total infusions1.21.43.2-0.30.30.4-0.5-0.50.51.3-1.81.7-1.6-1.21.1-1.71.0-1.50.5-1.3-1.6
Intermittent access day 15 total infusions0.60.72.60.10.7-0.4-0.1-0.10.10.3-1.01.6-0.9-0.50.4-1.41.0-1.3-0.0-1.0-0.9
Intermittent access terminal intake (last 3 days)0.30.31.50.20.7-0.30.00.0-0.00.1-0.81.2-0.7-0.20.2-0.90.6-0.8-0.2-0.5-0.4
Intermittent access total infusions1.21.34.20.20.9-0.1-0.1-0.10.10.9-1.62.1-1.5-1.00.9-1.81.3-1.70.3-1.3-1.3
Intermittent access day 1 locomotion1.01.12.5-0.20.00.4-0.4-0.40.41.1-1.21.3-1.2-1.11.1-1.61.1-1.50.9-1.4-1.2
Intermittent access day 15 total locomotion0.30.30.7-0.6-0.20.5-0.3-0.30.30.6-0.70.6-0.8-0.60.5-0.9-0.0-0.70.3-0.5-0.5
Intermittent access total locomotion1.61.83.9-1.1-0.71.3-1.0-1.01.01.5-1.81.1-1.7-1.51.4-2.00.6-1.81.2-1.4-1.4
Intermittent access standard deviation1.71.85.5-0.8-0.30.6-0.9-0.90.91.3-1.71.3-1.3-1.11.1-2.31.1-2.30.8-2.0-1.4
Left kidney weight5.415.338.0-6.2-5.05.6-4.8-4.84.84.5-4.3-1.9-4.1-3.73.2-2.0-2.9-1.52.9-1.2-1.7
Right kidney weight7.721.649.2-7.0-6.16.2-5.7-5.75.75.4-4.8-1.7-4.8-4.64.2-2.9-2.4-2.74.0-2.3-2.6
Cocaine induced anxiety0.30.41.5-0.8-0.81.2-0.5-0.50.50.8-0.0-0.8-0.2-0.50.40.3-0.70.20.60.20.5
Post-drug Anxiety1.41.63.4-1.3-1.81.6-1.9-1.91.91.0-0.5-1.3-0.6-1.31.3-0.0-0.50.11.80.00.2
Baseline Anxiety0.20.20.70.4-0.2-0.3-0.3-0.30.3-0.80.7-0.40.40.00.20.50.20.60.50.50.2
Tail length0.10.42.0-1.4-1.30.7-0.7-0.70.70.10.3-1.10.40.00.10.3-0.40.10.60.30.3
Length with tail1.76.115.0-3.9-3.83.2-3.6-3.63.62.2-1.9-1.9-1.7-1.91.8-0.8-1.6-0.72.1-0.2-0.5
Length without tail3.16.814.9-3.5-3.53.3-3.9-3.93.92.5-2.6-1.3-2.6-2.42.1-1.3-1.8-1.02.0-0.5-0.9
Times rat made contact with spout0.10.10.5-0.20.2-0.60.30.3-0.3-0.70.30.20.20.4-0.3-0.1-0.2-0.2-0.20.30.5
Lifetime Intake1.72.05.0-0.10.70.4-0.3-0.30.31.3-2.02.2-1.9-1.41.3-2.11.3-2.00.6-1.8-1.7
Liver weight, left0.81.23.3-1.2-1.71.2-1.8-1.81.80.9-0.9-1.3-0.4-0.30.1-0.0-1.40.30.10.40.3
Liver weight, right2.03.310.4-2.2-2.62.3-2.1-2.12.11.0-0.6-3.0-0.00.0-0.31.0-3.21.30.01.71.5
Locomotor activity0.91.54.9-1.6-2.21.8-1.5-1.51.51.8-1.0-0.9-0.9-0.90.7-0.7-0.9-0.60.8-0.5-0.3
Locomotor testing distance0.20.41.00.4-0.4-0.10.10.1-0.1-0.30.8-0.60.81.0-1.00.5-0.80.5-0.80.60.8
Locomotor testing rearing0.30.51.7-0.6-1.31.2-0.8-0.80.81.3-0.4-0.5-0.5-0.40.2-0.3-0.9-0.40.2-0.4-0.1
Locomotion in novel chamber4.25.210.01.71.2-2.11.51.5-1.5-3.02.9-1.53.22.8-2.62.6-0.82.8-2.02.62.7
Locomotion in novel chamber post-restriction1.92.25.12.31.8-1.82.02.0-2.0-1.31.10.41.41.6-1.70.8-0.01.0-1.80.80.9
Fecal boli incidents, locomotor time 11.51.73.90.10.4-0.1-0.3-0.30.30.5-1.31.8-1.3-1.41.5-2.01.9-2.01.3-1.7-1.6
Change in fecal boli incidents, locomotor task0.90.83.5-1.0-0.90.3-0.5-0.50.5-0.3-0.0-1.10.10.6-0.81.0-1.91.0-0.91.50.9
Time >=10cm from walls, locomotor time 11.61.62.7-1.1-0.91.0-1.1-1.11.11.5-1.60.6-1.5-1.51.5-1.60.6-1.41.3-1.3-1.3
Bouts of movement, locomotor time 10.30.31.1-1.0-0.60.7-0.4-0.40.40.5-0.8-0.2-0.7-0.40.3-0.3-0.8-0.20.1-0.0-0.4
Total resting periods, locomotor time 10.30.41.1-0.7-0.40.6-0.4-0.40.40.6-1.00.3-0.9-0.70.7-0.7-0.1-0.60.5-0.5-0.7
Rest time, locomotor task time 11.01.12.4-1.0-0.30.9-0.3-0.30.30.8-1.40.8-1.3-1.51.5-1.20.8-1.21.5-1.2-1.4
Distance moved, locomotor task time 10.60.72.10.0-0.90.3-0.6-0.60.60.10.9-1.40.70.6-0.61.1-1.21.1-0.41.01.1
Vertical activity count, locomotor time 10.60.61.9-1.0-1.40.9-1.1-1.11.10.20.6-1.30.40.00.10.4-0.60.20.70.50.5
Time >=10cm from walls, locomotor time 20.70.72.3-1.1-0.70.7-0.8-0.80.80.4-1.00.1-0.7-1.11.3-0.80.8-0.71.5-0.5-0.5
Bouts of movement, locomotor time 20.70.71.80.60.8-0.21.31.3-1.3-0.00.90.10.50.9-1.10.6-0.70.5-1.30.30.4
Total resting periods, locomotor time 20.70.72.40.81.1-0.51.51.5-1.50.10.60.70.20.7-0.90.3-0.30.1-1.3-0.10.0
Rest time, locomotor task time 20.30.41.1-0.10.5-0.40.60.6-0.6-0.0-0.71.1-0.7-0.40.4-0.60.7-0.80.1-0.6-0.9
Distance moved, locomotor task time 20.40.51.9-0.6-1.30.8-0.9-0.90.90.30.2-1.40.2-0.20.20.4-0.80.60.60.40.4
Vertical activity count, locomotor time 20.80.82.7-1.7-1.51.4-1.1-1.11.10.7-0.4-0.9-0.3-0.70.8-0.2-0.4-0.21.2-0.1-0.1
Light reinforcement 10.00.10.50.7-0.00.1-0.1-0.10.10.30.20.20.0-0.20.1-0.00.4-0.10.2-0.2-0.1
Light reinforcement 20.30.41.3-0.0-0.70.7-0.4-0.40.40.40.3-1.10.50.4-0.60.6-1.10.5-0.40.71.0
Bone: marrow area1.83.97.0-2.5-1.82.0-2.2-2.22.22.3-2.60.2-2.2-2.32.2-1.90.4-1.62.0-1.5-1.7
Bone: maximum diameter2.54.58.1-2.8-2.32.5-2.1-2.12.12.8-2.50.1-2.5-2.52.3-1.8-0.0-1.82.1-1.7-1.8
Bone: maximum force2.03.56.7-2.1-0.71.3-0.9-0.90.92.3-2.51.5-2.6-2.42.2-2.31.0-2.41.6-2.1-2.1
Bone: maximum moment2.44.17.6-2.2-0.91.5-1.1-1.11.12.5-2.71.6-2.8-2.62.4-2.41.1-2.51.8-2.2-2.2
Mean time between licks in bursts0.50.73.01.71.2-1.20.90.9-0.9-0.70.40.50.80.6-0.60.31.00.4-0.60.30.1
Mean num. licks in bursts0.50.61.4-1.2-1.10.9-1.2-1.21.20.7-0.4-0.7-0.4-0.40.4-0.2-0.80.00.50.00.0
Cd content in liver0.80.82.00.2-0.2-0.3-0.2-0.20.2-0.21.2-0.91.21.2-1.31.2-0.91.4-1.21.20.8
Co content in liver0.00.10.2-0.0-0.0-0.30.20.2-0.20.10.40.10.50.3-0.30.10.30.0-0.30.0-0.2
Cu content in liver3.23.98.22.92.4-2.72.42.4-2.4-2.22.40.52.22.0-1.81.30.91.2-1.61.01.0
Fe content in liver2.22.77.4-2.3-2.31.7-2.7-2.72.71.6-1.1-1.2-0.6-1.21.2-0.9-0.1-0.61.6-0.6-0.5
K content in liver0.40.41.10.30.8-0.30.70.7-0.7-0.0-0.70.9-0.3-0.20.3-0.61.0-0.60.1-0.8-0.6
Mg content in liver0.30.31.10.10.6-0.20.20.2-0.20.2-0.60.8-0.3-0.40.5-0.71.1-0.70.4-0.9-0.7
Mn content in liver0.60.72.20.70.7-0.50.80.8-0.8-0.80.2-0.30.61.1-1.30.6-1.00.6-1.50.80.8
Na content in liver0.20.20.60.70.5-0.70.20.2-0.2-0.70.60.10.80.5-0.40.10.70.3-0.10.20.5
Rb content in liver0.10.10.40.20.3-0.2-0.2-0.20.2-0.1-0.20.5-0.3-0.30.4-0.50.6-0.60.4-0.4-0.6
Se content in liver2.73.46.51.00.6-1.61.01.0-1.0-1.72.2-1.42.42.5-2.52.1-1.32.2-2.32.12.3
Sr content in liver4.23.86.72.62.1-2.32.22.2-2.2-2.42.10.12.22.3-2.21.5-0.01.5-2.11.41.5
Zn content in liver0.80.92.11.00.9-1.41.51.5-1.5-0.90.80.20.90.9-0.90.70.40.7-0.90.50.7
Bone: minimum diameter0.81.63.1-1.6-0.91.4-0.6-0.60.61.7-1.80.6-1.6-1.51.3-1.40.3-1.41.1-1.2-1.6
Time in familiar zone, hab. session 10.30.31.2-0.40.5-0.20.10.1-0.1-0.1-1.10.9-0.9-0.60.5-0.60.5-0.50.2-0.2-1.0
Time in novel zone, hab. session 10.60.62.0-0.5-1.41.2-1.1-1.11.11.00.4-1.10.3-0.20.10.2-0.50.20.5-0.10.7
Total zone transitions, hab. session 12.94.07.31.91.8-2.71.81.8-1.8-2.71.9-0.12.02.5-2.51.8-0.61.9-2.62.11.6
Total locomotion distance, hab. session 11.52.14.00.80.6-1.30.80.8-0.8-1.81.4-0.81.62.0-2.01.6-1.21.7-2.01.81.4
Locomotion velocity, hab. session 11.42.03.61.31.0-1.61.11.1-1.1-1.91.6-0.41.51.8-1.81.4-0.71.4-1.81.51.2
Time in familiar zone, hab. session 21.11.22.50.50.4-0.50.60.6-0.6-1.31.1-1.11.31.3-1.31.4-1.01.4-1.11.61.4
Time in novel zone, hab. session 21.01.02.5-0.6-0.40.5-0.4-0.40.41.2-0.91.0-1.1-1.01.0-1.30.9-1.40.8-1.6-1.5
Total zone transitions, hab. session 20.70.93.10.81.5-1.60.80.8-0.8-0.7-0.31.7-0.4-0.10.2-0.81.4-0.7-0.1-0.5-1.1
Total locomotion distance, hab. session 20.60.82.70.71.0-0.90.30.3-0.3-0.1-0.71.6-0.5-0.40.5-1.31.7-1.10.2-1.1-1.3
Locomotion velocity, hab. session 20.81.03.61.01.2-1.20.50.5-0.5-0.3-0.51.8-0.4-0.40.5-1.31.9-1.20.2-1.1-1.3
Novel to familiar place preference ratio1.21.23.7-1.5-1.91.0-1.6-1.61.60.90.3-1.60.00.0-0.20.8-1.50.80.00.80.7
Novelty place preference1.61.74.6-1.6-2.11.1-1.7-1.71.70.80.4-1.90.10.2-0.31.1-2.01.1-0.11.11.0
Time in novel zone, NPP test1.92.05.3-1.7-2.31.2-1.9-1.91.90.90.4-2.10.10.2-0.41.1-2.21.2-0.11.21.1
Total zone transitions, NPP test1.92.67.71.82.2-2.81.81.8-1.8-2.41.30.91.21.7-1.60.90.40.9-1.91.10.7
Total locomotion distance, NPP test0.30.52.01.01.1-1.40.50.5-0.5-1.00.11.00.00.3-0.3-0.20.8-0.1-0.6-0.1-0.4
Locomotion velocity, NPP test0.60.93.11.51.6-1.71.01.0-1.0-1.40.41.00.40.7-0.60.00.80.1-0.90.1-0.2
Intraocular pressure0.60.82.9-1.2-0.81.1-0.7-0.70.71.0-1.7-0.0-1.2-0.80.6-0.9-0.6-0.50.3-0.3-1.0
Delta distance traveled before/after self-admin2.52.77.2-2.7-2.41.5-1.9-1.91.91.4-1.7-0.6-1.6-1.71.7-1.3-0.3-1.11.9-0.8-1.0
Delta ambulatory time before/after self-admin3.03.36.9-2.6-2.31.3-2.0-2.02.01.7-2.1-0.1-2.0-2.12.1-1.80.2-1.52.1-1.3-1.5
Parametrial fat weight0.20.51.3-0.8-0.90.4-0.2-0.20.2-0.40.9-1.20.50.3-0.20.9-1.00.90.20.80.7
Pavlov. Cond. lever latency0.20.30.9-1.0-0.60.7-0.5-0.50.50.7-0.8-0.0-0.7-0.50.4-0.3-0.3-0.20.2-0.2-0.2
Pavlov. Cond. magazine entry latency0.91.12.81.41.6-1.31.41.4-1.4-0.5-0.21.7-0.10.2-0.1-0.81.4-1.0-0.5-0.7-0.7
Pavlov. Cond. change in total contacts1.41.53.91.71.8-1.31.51.5-1.5-0.4-0.32.0-0.20.00.1-1.01.7-1.2-0.3-1.0-1.0
Pavlov. Cond. index score0.40.51.30.60.8-0.50.60.6-0.6-0.0-0.41.1-0.4-0.30.4-0.81.0-1.00.2-0.9-0.8
Pavlov. Cond. latency score0.20.30.70.60.6-0.40.40.4-0.4-0.0-0.30.8-0.2-0.20.3-0.60.8-0.70.2-0.7-0.5
Pavlov. Cond. lever contacts0.30.41.41.20.8-0.70.70.7-0.7-0.50.30.70.20.10.1-0.30.9-0.40.1-0.5-0.4
Pavlov. Cond. magazine entry number0.60.72.2-0.9-1.51.1-1.2-1.21.20.70.2-1.30.1-0.20.20.5-0.90.60.60.40.3
Pavlov. Cond. intertrial magazine entries0.10.10.60.40.0-0.70.00.0-0.0-0.50.80.10.30.00.20.20.50.00.40.0-0.2
Pavlov. Cond. lever-magazine prob. diff.0.40.51.10.91.0-0.70.90.9-0.9-0.4-0.11.1-0.2-0.00.1-0.50.9-0.7-0.1-0.6-0.5
Pavlov. Cond. response bias0.60.82.01.11.4-0.91.01.0-1.0-0.4-0.31.4-0.2-0.10.2-0.91.2-1.0-0.1-0.8-0.7
Pavlov. Cond. lever latency0.20.31.4-0.20.10.20.80.8-0.8-0.00.1-0.0-0.30.4-0.60.4-1.20.1-1.00.40.4
Pavlov. Cond. magazine entry latency0.70.84.00.81.2-1.30.60.6-0.6-0.4-0.01.50.1-0.20.4-0.82.0-0.60.4-0.9-1.0
Pavlov. Cond. change in total contacts2.94.07.7-1.4-0.81.0-1.6-1.61.61.7-2.31.3-1.9-2.62.7-2.32.3-2.02.8-2.2-2.5
Pavlov. Cond. index score0.40.53.00.30.6-0.7-0.1-0.10.1-0.2-0.40.90.0-0.50.7-0.81.7-0.60.9-0.7-0.8
Pavlov. Cond. latency score0.50.63.60.40.7-0.8-0.1-0.10.1-0.3-0.41.0-0.0-0.50.8-0.91.9-0.71.0-0.8-0.9
Pavlov. Cond. lever contacts0.20.21.00.40.0-0.2-0.6-0.60.6-0.20.2-0.10.5-0.20.4-0.21.00.10.9-0.2-0.0
Pavlov. Cond. magazine entry number0.20.31.7-0.2-0.50.70.10.1-0.10.20.2-0.80.10.4-0.60.6-1.30.4-0.70.60.6
Pavlov. Cond. intertrial magazine entries0.40.51.3-0.9-0.30.9-0.1-0.10.10.6-0.70.4-1.1-0.80.8-0.7-0.2-0.80.5-0.8-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.42.60.30.5-0.7-0.1-0.10.1-0.2-0.20.70.2-0.40.6-0.61.6-0.40.8-0.6-0.6
Pavlov. Cond. response bias0.30.52.60.40.4-0.4-0.3-0.30.30.1-0.40.8-0.1-0.60.8-0.81.6-0.51.0-0.8-0.8
Time in closed arm before self-admin0.81.05.22.01.0-0.90.70.7-0.7-0.30.91.00.90.10.1-0.52.3-0.50.5-1.0-0.5
Time in closed arm after self-admin0.80.82.1-0.2-0.81.5-1.1-1.11.11.0-0.40.1-0.7-1.01.1-0.90.2-0.81.2-0.8-0.8
Time in open arm before self-admin0.40.41.1-0.9-0.40.2-0.3-0.30.3-0.6-0.3-1.00.10.3-0.30.6-1.10.8-0.21.00.8
Time in open arm after self-admin0.91.02.00.40.3-0.80.70.7-0.7-1.31.1-1.01.41.3-1.21.2-0.61.0-0.81.31.3
Bone: periosteal estimation1.53.15.3-2.2-1.51.8-1.6-1.61.62.3-2.30.4-2.1-2.12.0-1.80.3-1.81.7-1.5-1.6
Bone: periosteal perimeter2.54.29.2-3.0-2.22.5-2.0-2.02.02.7-2.6-0.1-2.3-2.32.1-1.7-0.2-1.71.9-1.5-1.7
Bone: post-yield work0.71.03.40.10.6-0.20.60.6-0.60.8-0.51.8-1.3-1.21.2-1.01.4-1.10.6-1.5-1.1
Progressive ratio test 1 active lever presses1.11.13.90.50.9-0.30.20.2-0.20.6-1.32.0-1.3-0.90.9-1.71.3-1.40.4-1.3-1.2
Progressive ratio test 1 breakpoint0.60.72.40.50.8-0.30.10.1-0.10.3-1.01.5-1.0-0.70.7-1.31.0-1.00.3-0.9-0.8
Progressive ratio test 1 inactive lever presses1.01.13.40.91.5-0.40.80.8-0.80.3-0.71.8-0.4-0.60.7-1.21.8-0.80.5-1.4-1.4
Progressive ratio test 2 active lever presses0.50.52.2-0.01.1-0.40.80.8-0.8-0.3-0.71.5-0.9-0.20.2-0.90.4-0.9-0.3-0.5-0.7
Progressive ratio test 2 breakpoint0.60.72.7-0.10.9-0.20.60.6-0.60.1-1.11.6-1.2-0.60.6-1.20.7-1.10.1-0.9-1.1
Progressive ratio test 2 inactive lever presses1.01.14.20.82.1-1.21.41.4-1.4-0.8-0.32.0-0.40.1-0.0-0.71.3-0.7-0.5-0.6-0.7
Incentive Sensitization - Responses0.30.30.9-0.30.5-0.30.70.7-0.7-0.90.2-0.10.30.7-0.60.5-0.60.5-0.70.60.3
Incentive Sensitization - Breakpoint0.30.30.7-0.40.5-0.20.70.7-0.7-0.80.1-0.10.20.6-0.60.5-0.70.5-0.70.50.2
Sum of active levers in priming session hrs 5-60.10.10.50.30.4-0.50.50.5-0.5-0.1-0.10.40.1-0.00.1-0.20.7-0.50.1-0.4-0.4
Progressive ratio0.20.31.0-0.00.10.0-0.4-0.40.40.4-0.30.7-0.4-0.60.7-0.61.0-0.60.7-0.7-0.4
Food seeking constrained by brief footshock0.10.10.40.10.20.40.00.0-0.00.6-0.30.5-0.6-0.30.1-0.2-0.1-0.2-0.3-0.3-0.2
Seeking ratio, punishment vs. effort0.10.10.20.30.30.10.50.5-0.50.1-0.10.2-0.20.1-0.2-0.1-0.3-0.0-0.4-0.0-0.2
Retroperitoneal fat weight2.47.821.0-4.0-4.44.6-3.7-3.73.73.0-1.5-2.8-2.0-1.91.5-0.0-3.3-0.11.70.0-0.2
Reaction time number correct1.82.64.30.61.1-1.51.41.4-1.4-1.91.1-0.91.62.0-2.11.8-1.32.1-2.12.11.8
Reaction time mean minus median0.00.00.1-0.2-0.20.40.00.0-0.00.2-0.2-0.1-0.0-0.20.3-0.10.2-0.10.4-0.3-0.2
Reaction time mean minus median AUC0.20.20.8-0.5-0.80.9-0.4-0.40.40.6-0.3-0.6-0.1-0.30.3-0.0-0.4-0.10.5-0.1-0.2
Reaction time num false alarms0.10.10.4-0.3-0.70.5-0.4-0.40.40.20.2-0.50.50.3-0.40.2-0.30.0-0.10.20.1
Reaction time num false alarms AUC0.10.10.3-0.1-0.50.3-0.4-0.40.40.00.3-0.50.60.5-0.60.4-0.40.2-0.40.40.3
Reaction time trials correct on left1.82.64.30.61.1-1.51.41.4-1.4-1.91.1-0.91.62.0-2.11.8-1.32.1-2.12.11.8
Reaction time trials on left2.02.84.70.71.2-1.61.51.5-1.5-1.91.2-0.91.62.1-2.11.9-1.32.1-2.22.11.8
Reaction time mean0.10.10.7-0.2-0.40.4-0.4-0.40.40.30.3-0.3-0.0-0.50.60.10.4-0.00.8-0.5-0.1
Reaction time mean AUC0.00.10.3-0.2-0.20.2-0.2-0.20.20.10.3-0.30.0-0.30.40.20.20.10.5-0.30.0
Median of all reaction times0.10.10.50.0-0.10.1-0.2-0.20.20.10.4-0.1-0.0-0.40.50.00.6-0.10.7-0.6-0.0
Reaction time omissions0.91.23.20.81.6-1.31.81.8-1.8-0.5-0.31.20.40.9-1.00.00.50.2-1.6-0.2-0.2
Reaction time false alarm rate0.20.30.7-0.3-0.80.9-0.8-0.80.80.7-0.0-0.20.0-0.20.2-0.30.1-0.60.4-0.4-0.3
Reaction time premature initiation rate1.31.74.1-0.8-0.81.0-0.7-0.70.71.6-1.11.0-1.2-1.51.5-1.61.3-1.61.5-1.9-2.0
Reaction time premature initiations0.20.31.3-0.7-0.40.4-0.1-0.10.10.7-0.60.4-0.5-0.60.6-0.70.5-0.60.5-0.9-1.1
Std. dev. reaction times0.30.51.6-1.3-1.01.1-0.8-0.80.80.8-0.4-0.5-0.4-0.60.6-0.2-0.1-0.20.8-0.5-0.5
Reaction time trials completed2.02.84.70.71.2-1.61.51.5-1.5-1.91.2-0.91.62.1-2.11.9-1.32.1-2.22.11.8
Reaction time trials AUC1.52.13.70.40.9-1.21.21.2-1.2-1.60.9-0.91.41.8-1.91.7-1.41.9-1.91.91.6
Run reversals in cocaine runway, females1.01.03.1-0.5-0.30.10.10.1-0.1-1.01.3-1.41.10.9-0.91.6-1.11.8-0.51.30.9
Run reversals in cocaine runway, males0.20.20.90.2-0.3-0.2-0.6-0.60.60.2-0.60.2-1.0-0.40.3-0.3-0.6-0.4-0.10.1-0.1
Latency to leave start box in cocaine runway0.20.30.7-0.5-0.50.6-0.6-0.60.60.8-0.6-0.8-0.2-0.1-0.10.1-0.80.2-0.20.30.4
Latency to leave start box in cocaine runway, F0.10.10.60.80.6-0.60.00.0-0.00.0-0.40.10.10.2-0.30.00.20.2-0.50.30.3
Latency to leave start box in cocaine runway, M0.90.93.0-1.7-1.31.6-0.9-0.90.91.1-0.3-1.2-0.4-0.30.10.3-1.50.00.00.00.3
Std. dev. time between licks in bursts0.30.42.00.60.2-0.3-0.3-0.30.30.0-0.50.8-0.2-0.60.7-0.91.4-0.70.8-0.8-0.6
Total sessions with >9 infusions1.51.63.5-1.0-0.51.2-0.6-0.60.61.6-1.71.2-1.9-1.61.5-1.70.5-1.61.1-1.5-1.3
Short access day 1 total inactive lever presses2.93.25.9-0.3-0.20.4-1.4-1.41.41.5-2.12.0-2.0-2.12.2-2.42.2-2.21.9-2.2-2.0
Short access day 10 total inactive lever presses1.51.74.5-2.1-1.71.3-1.9-1.91.90.8-1.0-0.6-0.9-1.21.3-0.8-0.0-0.71.6-0.6-0.9
Short access day 1 total infusions1.11.22.4-0.6-0.11.0-0.9-0.90.91.0-1.61.0-1.4-1.31.3-1.40.8-1.41.1-1.2-1.1
Short access day 10 total infusions2.22.44.8-0.5-0.11.0-0.8-0.80.82.0-2.01.7-2.0-1.71.6-2.21.1-2.01.0-2.0-2.0
Short access total infusions2.83.15.6-0.6-0.21.4-1.1-1.11.12.1-2.31.8-2.4-2.12.0-2.31.2-2.21.5-2.1-2.0
Short access day 1 locomotion1.01.13.00.40.20.4-0.2-0.20.20.8-1.31.3-0.9-1.01.0-1.71.4-1.70.9-1.4-1.0
Short access day 10 total locomotion0.91.03.20.30.20.20.20.2-0.20.5-0.71.1-0.2-0.60.8-1.81.7-1.71.0-1.7-1.3
Short access total locomotion2.72.86.7-0.3-0.61.3-0.9-0.90.91.8-1.91.4-1.7-1.91.9-2.61.5-2.31.9-2.3-1.9
One hour access (0.3 mA shock)1.72.06.31.92.5-2.02.02.0-2.0-1.00.12.10.10.8-0.9-0.41.0-0.5-1.5-0.2-0.2
Compulsive drug intake1.51.53.70.81.0-1.61.51.5-1.5-1.91.30.01.11.5-1.31.1-0.40.8-1.31.30.9
One hour access (shock baseline)0.20.31.00.81.0-0.20.30.3-0.30.3-0.41.0-0.3-0.10.0-0.60.6-0.5-0.3-0.6-0.4
Social response proportion0.50.51.90.5-0.1-0.1-0.2-0.20.21.3-0.70.6-0.2-0.70.6-1.01.4-0.80.6-1.3-0.7
Social responses0.40.62.01.40.7-0.60.70.7-0.70.3-0.41.3-0.4-0.20.1-0.71.0-0.7-0.2-0.8-1.0
Social time1.52.06.32.51.9-1.81.71.7-1.7-0.50.32.00.30.2-0.1-0.92.2-1.1-0.3-1.2-1.1
Soleus weight0.20.61.6-0.20.6-0.60.80.8-0.8-0.7-0.41.3-0.6-0.40.6-1.10.9-1.30.5-0.8-1.3
Bone: stiffness1.72.74.4-1.7-1.01.5-1.2-1.21.22.1-1.80.9-1.9-2.12.1-1.81.0-1.91.8-1.9-1.6
Tibialis anterior weight1.55.112.33.03.2-3.03.53.5-3.5-1.82.12.11.51.6-1.50.41.90.1-1.7-0.4-0.1
Time to tail flick, vehicle, before self-admin0.10.10.7-0.8-0.30.2-0.2-0.20.20.3-0.30.1-0.4-0.20.1-0.1-0.30.2-0.1-0.1-0.3
Time to tail flick, vehicle, after self-admin0.20.31.10.0-0.7-0.1-0.4-0.40.4-0.51.0-0.80.70.3-0.20.6-0.20.50.10.50.4
Time to tail flick, test, before self-admin0.70.72.00.90.8-0.81.41.4-1.4-0.51.10.50.30.7-0.80.6-0.30.4-1.10.10.2
Time to tail flick, test, after self-admin0.91.02.01.30.8-1.10.80.8-0.8-1.41.4-0.21.31.0-0.80.90.31.0-0.50.91.2
Delta time to tail flick, vehicle, before/after SA0.10.10.70.80.1-0.2-0.1-0.10.1-0.00.40.10.3-0.10.2-0.30.8-0.50.5-0.5-0.1
Delta time to tail flick, test, before/after SA1.61.43.51.00.5-0.90.30.3-0.3-1.61.6-0.91.91.4-1.21.5-0.01.6-0.61.51.6
Tibia length0.51.43.5-1.8-1.10.8-0.8-0.80.81.5-1.60.5-1.9-1.51.3-1.2-0.1-1.20.9-0.9-1.4
Ambulatory time before self-admin0.90.93.21.61.8-1.11.31.3-1.3-0.90.41.20.40.6-0.6-0.21.0-0.4-0.8-0.10.1
Ambulatory time after self-admin1.01.13.1-0.4-0.1-0.4-0.4-0.40.40.4-1.21.3-1.0-1.01.1-1.81.6-1.61.0-1.4-1.1
Bone: tissue strength0.40.41.4-1.2-0.70.6-0.8-0.80.80.5-0.8-0.2-0.5-0.40.3-0.4-0.4-0.30.3-0.1-0.1
Total heroin consumption0.30.41.20.40.7-0.91.11.1-1.10.1-0.10.9-0.20.3-0.5-0.10.1-0.2-0.9-0.1-0.3
Bone: trabecular number0.20.41.2-0.5-0.40.3-0.2-0.20.2-0.40.2-1.00.60.5-0.50.7-0.90.8-0.30.81.1
Bone: trabecular spacing1.41.94.3-0.8-0.20.5-0.2-0.20.21.4-1.61.5-2.0-1.81.8-1.71.0-1.71.3-1.7-2.1
Bone: trabecular thickness0.50.61.80.40.00.1-0.1-0.10.1-0.81.0-1.21.21.0-0.90.9-0.60.7-0.31.01.3
Bone: trabecular tissue density0.40.52.71.0-0.0-0.80.20.2-0.2-0.71.6-0.51.30.6-0.30.70.70.50.40.40.5
Water consumed over 24 hours0.10.10.5-0.4-0.3-0.2-0.3-0.30.30.0-0.10.3-0.3-0.10.1-0.5-0.1-0.7-0.0-0.30.1
Number of responses in last shaping day2.42.47.51.82.2-1.21.81.8-1.80.4-0.92.7-0.7-0.50.4-1.72.3-1.6-0.2-1.8-1.3