Hub : Genes

Itga7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Itga7 0.29 0.15 8.3e-05 0.15 0.16 0.16 0.16 2.3e-04 1.0e-04 9.8e-05 1.2e-04
2 pVTA mRNA stability Itga7 0.04 0.03 3.1e-03 0.02 0.02 0.02 0.02 1.1e-02 1.7e-02 8.9e-03 9.6e-03
3 Adipose isoform ratio XM_063264290.1 0.12 0.08 6.3e-09 0.07 0.07 0.06 0.06 7.4e-08 6.2e-08 1.5e-07 9.4e-08
4 pVTA gene expression Itga7 0.16 0.09 8.6e-11 0.14 0.12 0.13 0.12 3.1e-11 3.5e-10 2.6e-10 3.7e-10
5 NAcc gene expression Itga7 0.17 0.08 0.0e+00 0.19 0.18 0.19 0.19 2.5e-28 3.2e-27 1.8e-27 1.5e-27
6 Brain gene expression Itga7 0.2 0.12 1.8e-14 0.14 0.13 0.14 0.14 1.1e-12 9.3e-12 9.9e-13 1.0e-12
7 Adipose intron excision ratio chr7_1951997_1952890 0.06 0.04 2.7e-05 0.05 0.04 0.04 0.04 7.2e-06 1.9e-05 1.8e-05 1.1e-05
8 Adipose intron excision ratio chr7_1952638_1953879 0.05 0.03 3.8e-04 0.02 0.02 0.02 0.02 1.0e-03 1.8e-03 1.2e-03 3.4e-03
9 Adipose intron excision ratio chr7_1953009_1953879 0.05 0.03 4.1e-04 0.02 0.02 0.02 0.02 1.0e-03 1.9e-03 1.4e-03 3.2e-03
10 Liver mRNA stability Itga7 0.04 0.03 5.4e-04 0.02 0.02 0.02 0.02 1.3e-03 1.7e-03 3.5e-03 2.7e-03
11 Adipose isoform ratio NM_030842.1 0.08 0.05 2.2e-06 0.05 0.05 0.04 0.05 3.1e-06 7.0e-06 1.3e-05 6.6e-06
12 Adipose intron excision ratio chr7_1951997_1952507 0.06 0.04 3.9e-05 0.04 0.04 0.04 0.04 9.3e-06 2.6e-05 2.3e-05 1.4e-05
13 Adipose gene expression Itga7 0.25 0.14 0.0e+00 0.14 0.14 0.13 0.14 9.4e-16 6.4e-15 1.2e-14 1.8e-15
14 BLA gene expression Itga7 0.13 0.08 3.9e-07 0.12 0.12 0.11 0.12 4.9e-07 1.0e-06 2.9e-06 3.8e-07
15 NAcc mRNA stability Itga7 0.02 0.02 9.8e-03 0 0.01 0.01 0.01 2.0e-01 1.1e-02 1.5e-02 3.1e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.50.95.70.0-0.10.6-0.6-0.5-0.6-0.90.9-0.9-0.9-0.90.9-0.9-0.82.4
Area under the delay curve0.00.10.30.40.10.5-0.00.30.1-0.10.1-0.1-0.1-0.10.1-0.10.30.3
BMI with tail7.827.032.35.75.65.65.45.45.3-5.25.2-5.2-5.2-5.25.2-5.35.21.9
BMI without tail2.16.48.22.92.72.72.62.82.7-2.52.5-2.5-2.5-2.52.5-2.52.70.8
Body weight1.15.07.92.72.62.42.62.82.5-1.91.9-1.9-1.9-1.91.9-1.92.80.2
Weight adjusted by age0.10.10.2-0.2-0.1-0.3-0.00.3-0.20.3-0.30.30.30.3-0.30.40.1-0.4
Bone surface1.01.910.8-0.8-0.80.1-1.6-1.6-1.5-0.80.8-0.8-0.8-0.80.8-0.8-2.03.3
Bone volume1.12.011.8-0.5-0.50.4-1.3-1.4-1.3-1.11.1-1.1-1.1-1.11.1-1.1-1.83.4
Breakpoint value in progressive ratio session0.91.11.6-1.2-1.2-1.3-1.1-0.9-0.81.1-1.11.11.11.1-1.11.1-0.9-0.7
Number of licking bursts1.93.15.22.11.91.92.02.02.1-1.61.6-1.6-1.6-1.61.6-1.52.3-0.2
Context. condit. distance diff. score0.20.30.30.60.50.60.50.50.5-0.60.6-0.6-0.6-0.60.6-0.60.40.1
Locomotion velocity, session 10.30.42.50.30.20.8-0.2-0.3-0.4-0.50.5-0.5-0.5-0.50.5-0.5-0.31.6
Locomotion distance, session 10.40.52.4-0.6-0.6-0.0-1.0-1.1-1.0-0.10.1-0.1-0.1-0.10.1-0.1-1.21.5
Locomotion velocity, session 21.41.64.1-1.5-1.5-0.9-1.8-1.9-1.90.6-0.60.60.60.6-0.60.6-2.01.4
Locomotion distance, session 22.43.36.4-1.9-2.2-1.4-2.5-2.3-2.51.5-1.51.51.51.5-1.51.5-2.31.0
Locomotion velocity, session 34.85.46.2-2.4-2.4-2.4-2.3-2.2-2.42.5-2.52.52.52.5-2.52.5-2.1-1.0
Locomotion distance, session 30.10.10.2-0.2-0.3-0.3-0.2-0.2-0.20.4-0.40.40.40.4-0.40.4-0.1-0.4
Stereotopy head waving bouts, day 35.46.48.0-2.8-2.8-2.7-2.7-2.7-2.72.5-2.52.52.52.5-2.52.5-2.7-0.5
Stereotopy head waving duration, day 33.74.46.6-2.6-2.3-2.4-2.2-2.4-2.31.9-1.91.91.91.9-1.91.9-2.4-0.4
Locomotion velocity, session 70.10.10.3-0.3-0.3-0.1-0.4-0.5-0.50.0-0.00.00.00.0-0.00.0-0.60.5
Locomotion distance, session 70.10.10.60.40.30.10.50.50.5-0.10.1-0.1-0.1-0.10.1-0.10.5-0.7
Stereotopy head waving bouts, day 70.80.91.9-1.0-1.0-0.6-1.3-1.3-1.30.7-0.70.70.70.7-0.70.7-1.40.9
Stereotopy head waving duration, day 70.70.92.0-0.9-1.0-0.5-1.3-1.3-1.40.6-0.60.60.60.6-0.60.6-1.41.2
Locomotion velocity, session 81.21.43.3-1.1-1.5-0.6-1.8-1.6-1.80.8-0.80.80.80.8-0.80.8-1.71.3
Locomotion distance, session 80.30.51.1-0.6-0.9-0.5-1.1-0.7-0.90.6-0.60.60.60.6-0.60.6-0.80.2
Degree of sensitization distance0.60.60.80.80.80.90.70.70.8-0.90.9-0.9-0.9-0.90.9-0.90.60.4
Degree of sensitization stereotypy0.20.21.10.30.20.6-0.00.0-0.1-0.40.4-0.4-0.4-0.40.4-0.4-0.11.1
Conditioned locomotion0.81.02.31.21.20.81.51.51.4-0.40.4-0.4-0.4-0.40.4-0.41.5-1.0
Cocaine response after cond. corrected1.82.14.01.71.61.31.81.91.9-1.21.2-1.2-1.2-1.21.2-1.22.0-0.7
Cocaine response after cond. not corrected2.02.34.31.71.81.32.02.02.0-1.21.2-1.2-1.2-1.21.2-1.22.1-0.8
Cocaine response before conditioning0.40.50.7-0.9-0.6-0.8-0.5-0.8-0.70.7-0.70.70.70.7-0.70.7-0.8-0.1
Saline control response0.50.71.71.11.10.81.21.31.1-0.50.5-0.5-0.5-0.50.5-0.51.3-0.4
Bone: connectivity density0.30.42.8-0.1-0.10.3-0.5-0.4-0.5-0.60.6-0.6-0.6-0.60.6-0.6-0.61.7
Bone: cortical apparent density1.21.72.21.21.21.31.11.11.3-1.51.5-1.5-1.5-1.51.5-1.50.90.6
Bone: cortical area1.21.94.50.70.81.20.40.10.4-1.71.7-1.7-1.7-1.71.7-1.7-0.22.1
Bone: cortical porosity0.10.20.6-0.1-0.10.1-0.2-0.2-0.2-0.50.5-0.5-0.5-0.50.5-0.5-0.40.8
Bone: cortical porosity0.50.51.70.10.20.4-0.1-0.1-0.2-0.90.9-0.9-0.9-0.90.9-0.9-0.31.3
Bone: cortical thickness1.83.04.51.31.51.61.20.91.2-2.12.1-2.1-2.1-2.12.1-2.10.61.7
Bone: cortical thickness0.70.81.51.01.10.91.20.91.2-0.80.8-0.8-0.8-0.80.8-0.81.0-0.2
Bone: cortical tissue density0.91.21.61.01.01.00.90.91.1-1.31.3-1.3-1.3-1.31.3-1.30.70.5
Condit. Reinf. active minus inactive responses1.92.23.0-1.7-1.7-1.6-1.7-1.7-1.71.4-1.41.41.41.4-1.41.4-1.6-0.4
Condit. Reinf. active-inactive response ratio0.30.30.6-0.7-0.5-0.8-0.3-0.4-0.40.6-0.60.60.60.6-0.60.6-0.4-0.7
Condit. Reinf. active responses2.73.35.5-2.1-2.2-1.8-2.3-2.3-2.41.5-1.51.51.51.5-1.51.5-2.20.1
Condit. Reinf. inactive responses1.41.73.3-1.4-1.6-1.0-1.8-1.8-1.81.0-1.01.01.01.0-1.01.0-1.80.7
Incentive salience index mean1.31.53.0-1.4-1.6-1.1-1.7-1.7-1.70.9-0.90.90.90.9-0.91.0-1.60.3
Condit. Reinf. lever presses0.50.62.1-0.5-0.9-0.0-1.3-1.2-1.30.2-0.20.20.20.2-0.20.2-1.21.4
Condit. Reinf. active minus inactive responses2.53.24.4-1.8-1.6-2.1-1.2-1.4-1.32.0-2.02.02.02.0-2.02.0-1.2-1.7
Condit. Reinf. active-inactive response ratio1.21.34.1-0.7-0.6-1.2-0.2-0.2-0.21.4-1.41.41.41.4-1.41.4-0.0-2.0
Condit. Reinf. active responses1.72.43.5-1.8-1.5-1.9-1.3-1.6-1.51.6-1.61.61.61.6-1.61.6-1.5-0.7
Condit. Reinf. inactive responses0.30.40.9-0.8-0.7-0.7-0.8-1.0-0.90.4-0.40.40.40.4-0.40.4-1.00.5
Condit. Reinf. lever presses2.63.65.0-2.0-1.8-2.2-1.5-1.6-1.32.1-2.12.12.12.1-2.12.1-1.5-1.4
Condit. Reinf. lever reinforcers received1.31.92.8-1.5-1.3-1.7-1.0-1.3-1.11.5-1.51.51.51.5-1.51.5-1.1-1.0
Conditioned reinforcement - actives0.00.10.2-0.40.1-0.40.0-0.00.1-0.20.2-0.2-0.2-0.20.2-0.2-0.40.0
Conditioned reinforcement - inactives0.30.40.90.20.7-0.10.90.90.9-0.60.6-0.6-0.6-0.60.6-0.60.4-0.6
Conditioned locomotion1.92.56.1-2.3-1.7-2.2-1.7-1.9-1.61.2-1.21.21.21.2-1.21.2-2.5-0.0
Patch foraging indifference point 0 sec3.46.48.12.42.42.52.22.22.3-2.82.8-2.8-2.8-2.82.8-2.81.91.5
Patch foraging indifference point AUC0.71.01.4-1.0-1.1-1.0-1.0-0.8-1.01.1-1.11.11.11.1-1.11.2-0.7-0.7
Delay disc. indifference point, 0s delay2.02.24.91.50.91.90.40.80.6-1.71.7-1.7-1.7-1.71.7-1.70.62.2
Delay disc. indifference point, 16s delay0.20.20.3-0.4-0.4-0.2-0.4-0.6-0.50.4-0.40.40.40.4-0.40.4-0.50.1
Delay disc. indifference point, 2s delay0.40.40.90.70.20.9-0.00.30.3-0.70.7-0.7-0.7-0.70.7-0.70.40.9
Delay disc. indifference point, 24s delay0.30.30.80.90.50.90.40.80.6-0.40.4-0.4-0.4-0.40.4-0.40.70.3
Delay disc. indifference point, 4s delay0.30.30.9-0.4-0.7-0.1-0.9-0.7-0.80.2-0.20.20.20.2-0.20.2-0.70.8
Delay disc. indifference point, 8s delay0.20.20.70.70.40.40.50.80.5-0.10.1-0.1-0.1-0.10.1-0.10.9-0.5
Indifference point function ln k0.10.10.20.10.40.10.50.00.4-0.40.4-0.4-0.4-0.40.4-0.50.10.0
Indifference point function log k0.10.10.20.10.40.10.50.00.4-0.40.4-0.4-0.4-0.40.4-0.50.10.0
Patch foraging total patch changes 0 sec3.05.67.22.22.32.32.12.02.2-2.72.7-2.7-2.7-2.72.7-2.71.81.4
Patch foraging total patch changes 12 sec1.82.43.61.71.61.51.71.91.7-1.51.5-1.5-1.5-1.51.5-1.41.80.1
Patch foraging total patch changes 18 sec0.00.10.20.30.10.30.10.50.1-0.20.2-0.2-0.2-0.20.2-0.10.20.3
Patch foraging total patch changes 24 sec0.40.71.00.90.71.00.50.80.8-0.90.9-0.9-0.9-0.90.9-0.90.60.8
Patch foraging total patch changes 6 sec1.92.93.81.51.71.71.51.31.4-1.91.9-1.9-1.9-1.91.9-1.91.21.2
Patch foraging time to switch 0 sec0.30.51.50.70.60.80.40.40.3-0.80.8-0.8-0.8-0.80.8-0.80.21.2
Patch foraging water rate 0 sec0.30.71.60.90.80.61.01.11.3-0.60.6-0.6-0.6-0.60.6-0.61.3-0.8
Patch foraging water rate 12 sec0.50.92.11.01.20.71.31.11.5-0.70.7-0.7-0.7-0.70.7-0.81.3-0.7
Patch foraging water rate 18 sec0.50.85.50.20.3-0.50.80.80.90.6-0.60.60.60.6-0.60.61.2-2.3
Patch foraging water rate 24 sec1.62.26.61.61.60.82.12.12.3-0.50.5-0.5-0.5-0.50.5-0.52.6-2.2
Patch foraging water rate 6 sec0.71.04.3-0.8-0.6-1.3-0.1-0.20.11.0-1.01.01.01.0-1.01.1-0.0-2.1
Seeking ratio, delayed vs. immediate footshock1.21.43.1-1.6-1.4-1.4-1.5-1.6-1.10.9-0.90.90.90.9-0.91.0-1.80.2
Distance traveled before self-admin1.31.72.0-1.4-1.4-1.3-1.4-1.4-1.31.3-1.31.31.31.3-1.31.3-1.2-0.5
Distance traveled after self-admin0.00.00.00.10.00.10.00.20.10.2-0.20.20.20.2-0.20.20.2-0.1
Extensor digitorum longus weight4.919.125.25.04.94.44.94.95.0-4.24.2-4.2-4.2-4.24.2-4.24.90.4
Bone: elastic displacement0.00.00.00.00.10.10.00.10.2-0.10.1-0.1-0.1-0.10.1-0.1-0.00.1
Bone: elastic work1.01.31.71.11.01.20.70.80.9-1.31.3-1.3-1.3-1.31.3-1.30.71.1
Bone: endosteal estimation0.61.21.90.80.81.00.60.50.6-1.41.4-1.4-1.4-1.41.4-1.40.31.2
Bone: endosteal perimeter0.30.71.8-1.0-1.0-0.7-1.2-1.2-1.20.3-0.30.30.30.3-0.30.3-1.30.9
Epididymis fat weight0.10.51.7-0.2-0.2-0.50.00.20.10.8-0.80.80.80.8-0.80.80.3-1.3
Delta time in closed arm before/after self-admin1.41.33.81.11.30.51.71.61.9-0.60.6-0.6-0.6-0.60.6-0.61.8-1.5
Delta time in open arm before/after self-admin0.90.81.61.31.11.31.01.20.9-0.70.7-0.7-0.7-0.70.7-0.71.20.3
Diff in mean of infusions in LGA sessions2.02.43.1-1.7-1.6-1.8-1.5-1.5-1.41.6-1.61.61.61.6-1.61.6-1.4-0.8
Delay discount exponential model param0.00.00.1-0.30.0-0.40.1-0.2-0.0-0.00.0-0.0-0.0-0.00.0-0.0-0.2-0.2
Extinction: sum of active levers before priming1.82.02.7-1.3-1.3-1.6-1.0-0.9-1.01.6-1.61.61.61.6-1.61.6-0.7-1.4
Active lever presses in extinction session 60.20.20.5-0.5-0.6-0.4-0.7-0.5-0.60.3-0.30.30.30.3-0.30.3-0.60.2
Bone: final force3.15.07.01.92.12.41.51.31.5-2.62.6-2.6-2.6-2.62.6-2.70.92.5
Bone: final moment3.15.06.91.92.02.31.51.31.4-2.62.6-2.6-2.6-2.62.6-2.60.92.5
Food consumed during 24 hour testing period0.30.50.60.70.70.80.70.60.8-0.70.7-0.7-0.7-0.70.7-0.60.60.3
Glucose1.42.23.31.81.61.71.51.81.6-1.41.4-1.4-1.4-1.41.4-1.41.60.4
Heart weight0.30.50.9-0.6-0.6-0.8-0.3-0.2-0.40.8-0.80.80.80.8-0.80.8-0.3-1.0
Delay discount hyperbolic model param0.10.20.5-0.6-0.2-0.7-0.0-0.3-0.20.4-0.40.40.40.4-0.40.4-0.4-0.5
Intermittent access intake day 1-15 change0.40.71.9-1.1-0.7-1.4-0.4-0.4-0.30.9-0.90.90.90.9-0.90.9-0.6-1.2
Intermittent access intake escalation0.30.71.7-1.0-0.6-1.3-0.3-0.3-0.20.8-0.80.80.80.8-0.80.8-0.5-1.2
Intermittent access intake escalation 20.70.81.6-1.1-0.9-1.3-0.6-0.6-0.51.0-1.01.01.01.0-1.01.0-0.7-1.0
Intermitt. access day 1 inactive lever presses0.31.03.3-0.6-0.5-1.10.00.0-0.21.2-1.21.21.21.2-1.21.20.2-1.8
Intermitt. access day 15 inactive lever presses0.61.21.6-1.0-1.1-1.2-0.9-0.9-1.01.2-1.21.21.21.2-1.21.2-0.6-0.9
Intermitt. access escalation Index0.20.31.40.10.10.4-0.1-0.10.0-0.60.6-0.6-0.6-0.60.6-0.6-0.41.2
Intermittent access day 1 total infusions0.10.20.50.30.50.20.60.50.7-0.50.5-0.5-0.5-0.50.5-0.50.20.1
Intermittent access day 15 total infusions0.00.10.2-0.40.0-0.50.1-0.10.2-0.20.2-0.2-0.2-0.20.2-0.2-0.50.1
Intermittent access terminal intake (last 3 days)0.10.10.7-0.5-0.2-0.5-0.3-0.5-0.1-0.20.2-0.2-0.2-0.20.2-0.2-0.80.5
Intermittent access total infusions0.20.20.30.00.3-0.00.20.20.4-0.60.6-0.6-0.6-0.60.6-0.6-0.20.4
Intermittent access day 1 locomotion0.10.10.40.20.3-0.10.60.60.60.1-0.10.10.10.1-0.10.10.4-0.6
Intermittent access day 15 total locomotion0.20.31.3-0.9-0.4-1.2-0.1-0.1-0.10.5-0.50.50.50.5-0.50.5-0.6-0.9
Intermittent access total locomotion0.10.20.5-0.5-0.3-0.7-0.20.10.00.4-0.40.40.40.4-0.40.4-0.4-0.5
Intermittent access standard deviation0.40.92.7-1.5-1.0-1.4-0.9-1.3-1.00.6-0.60.60.60.6-0.60.6-1.60.1
Left kidney weight0.00.00.10.20.10.10.10.20.10.2-0.20.20.20.2-0.20.20.4-0.4
Right kidney weight0.20.81.3-0.6-0.7-0.7-0.5-0.4-0.61.1-1.11.11.11.1-1.11.1-0.3-0.8
Cocaine induced anxiety1.21.63.4-1.5-1.6-1.1-1.8-1.7-1.60.9-0.90.90.90.9-0.90.9-1.80.7
Post-drug Anxiety0.80.83.0-1.0-1.2-0.5-1.6-1.2-0.90.2-0.20.20.20.2-0.20.2-1.71.4
Baseline Anxiety0.00.00.10.10.10.10.10.10.3-0.20.2-0.2-0.2-0.20.2-0.20.10.0
Tail length3.413.416.0-3.8-3.8-4.0-3.4-3.3-3.43.9-3.93.93.93.9-3.94.0-3.0-2.0
Length with tail1.56.48.5-2.5-2.3-2.8-1.9-1.9-2.12.9-2.92.92.92.9-2.92.9-1.7-1.9
Length without tail0.20.71.50.91.10.81.21.11.0-0.60.6-0.6-0.6-0.60.6-0.61.2-0.2
Times rat made contact with spout1.01.22.31.31.31.11.31.41.2-0.90.9-0.9-0.9-0.90.9-0.91.5-0.2
Lifetime Intake0.80.91.50.40.80.40.70.60.9-1.21.2-1.2-1.2-1.21.2-1.20.00.7
Liver weight, left0.40.60.90.90.90.90.80.80.9-0.70.7-0.7-0.7-0.70.7-0.70.90.2
Liver weight, right0.20.30.5-0.1-0.3-0.3-0.10.2-0.20.7-0.70.70.70.7-0.70.70.2-0.6
Locomotor activity2.84.46.7-2.3-2.2-2.0-2.3-2.3-2.62.0-2.02.02.02.0-2.02.0-2.40.0
Locomotor testing distance1.22.23.5-1.7-1.6-1.5-1.7-1.7-1.81.3-1.31.31.31.3-1.31.3-1.90.2
Locomotor testing rearing0.00.10.20.00.1-0.10.20.30.00.3-0.30.30.30.3-0.30.30.2-0.4
Locomotion in novel chamber0.10.10.30.10.30.10.30.10.4-0.40.4-0.4-0.4-0.40.4-0.5-0.00.2
Locomotion in novel chamber post-restriction3.55.66.5-2.5-2.6-2.4-2.4-2.5-2.22.5-2.52.52.52.5-2.52.4-2.2-1.1
Fecal boli incidents, locomotor time 10.60.82.11.21.20.91.31.21.2-0.50.5-0.5-0.5-0.50.5-0.51.5-0.5
Change in fecal boli incidents, locomotor task0.70.61.8-0.9-0.9-0.5-1.2-1.2-1.20.3-0.30.30.30.3-0.30.3-1.31.0
Time >=10cm from walls, locomotor time 10.70.82.30.60.61.00.30.30.2-1.01.0-1.0-1.0-1.01.0-1.00.11.5
Bouts of movement, locomotor time 10.70.81.1-1.0-0.8-1.0-0.7-0.8-0.90.9-0.90.90.90.9-0.90.9-0.7-0.6
Total resting periods, locomotor time 11.41.51.9-1.3-1.3-1.4-1.2-1.2-1.31.3-1.31.31.31.3-1.31.3-1.1-0.6
Rest time, locomotor task time 10.40.60.9-0.8-0.8-0.6-0.9-0.8-0.90.7-0.70.70.70.7-0.70.7-0.80.2
Distance moved, locomotor task time 10.71.12.60.70.71.10.40.40.3-1.31.3-1.3-1.3-1.31.3-1.30.01.6
Vertical activity count, locomotor time 10.61.41.71.01.21.01.21.11.2-1.31.3-1.3-1.3-1.31.3-1.30.80.4
Time >=10cm from walls, locomotor time 20.81.11.91.11.20.91.31.31.4-1.01.0-1.0-1.0-1.01.0-1.01.2-0.2
Bouts of movement, locomotor time 20.20.31.0-0.5-0.4-0.2-0.6-0.9-0.90.1-0.10.10.10.1-0.10.1-0.81.0
Total resting periods, locomotor time 20.20.31.4-0.5-0.4-0.2-0.6-0.9-1.0-0.00.0-0.0-0.0-0.00.0-0.0-0.91.2
Rest time, locomotor task time 20.10.10.6-0.3-0.2-0.0-0.5-0.4-0.50.0-0.00.00.00.0-0.00.0-0.60.8
Distance moved, locomotor task time 20.10.10.50.10.2-0.10.40.50.30.1-0.10.10.10.1-0.10.10.4-0.7
Vertical activity count, locomotor time 20.91.22.41.21.20.91.51.61.5-0.80.8-0.8-0.8-0.80.8-0.81.5-0.7
Light reinforcement 12.45.98.3-2.9-2.6-2.8-2.6-2.6-2.72.3-2.32.32.32.3-2.32.3-2.8-0.6
Light reinforcement 20.81.31.9-1.3-1.2-1.4-1.1-1.2-1.21.1-1.11.11.11.1-1.11.1-1.2-0.4
Bone: marrow area0.51.11.70.70.80.90.50.50.6-1.31.3-1.3-1.3-1.31.3-1.30.31.2
Bone: maximum diameter0.50.92.8-1.2-1.1-0.7-1.4-1.5-1.30.2-0.20.20.20.2-0.20.2-1.71.2
Bone: maximum force2.95.17.02.02.12.41.61.51.6-2.62.6-2.6-2.6-2.62.6-2.71.12.3
Bone: maximum moment2.95.17.02.12.12.41.61.51.6-2.62.6-2.6-2.6-2.62.6-2.61.12.2
Mean time between licks in bursts0.41.11.7-1.3-1.3-1.3-1.1-1.1-0.91.0-1.01.01.01.0-1.01.0-1.0-0.6
Mean num. licks in bursts0.40.61.0-0.9-0.8-0.9-0.8-0.7-1.00.8-0.80.80.80.8-0.80.8-0.90.0
Cd content in liver0.30.40.8-0.8-0.8-0.8-0.9-0.7-0.60.4-0.40.40.40.4-0.40.4-0.9-0.1
Co content in liver2.73.24.2-1.9-1.8-2.0-1.6-1.5-1.51.9-1.91.91.91.9-1.91.9-1.4-1.3
Cu content in liver0.60.72.10.20.40.60.10.0-0.0-1.11.1-1.1-1.1-1.11.1-1.1-0.41.5
Fe content in liver0.10.20.30.40.50.30.60.50.5-0.40.4-0.4-0.4-0.40.4-0.40.4-0.2
K content in liver0.70.71.5-1.0-0.8-0.8-1.0-1.0-1.10.6-0.60.60.60.6-0.60.6-1.20.6
Mg content in liver1.11.21.8-1.2-1.2-1.1-1.3-1.3-1.31.0-1.01.01.01.0-1.01.0-1.20.1
Mn content in liver1.71.95.2-1.6-1.5-0.9-1.9-2.0-2.10.6-0.60.60.60.6-0.60.6-2.31.7
Na content in liver0.20.20.70.30.30.60.20.50.0-0.40.4-0.4-0.4-0.40.4-0.4-0.10.8
Rb content in liver0.50.62.70.10.30.5-0.1-0.2-0.1-0.90.9-0.9-0.9-0.90.9-0.9-0.51.6
Se content in liver0.00.00.1-0.1-0.1-0.1-0.2-0.2-0.30.1-0.10.10.10.1-0.10.1-0.1-0.0
Sr content in liver0.20.20.6-0.5-0.3-0.7-0.20.0-0.00.4-0.40.40.40.4-0.40.4-0.4-0.8
Zn content in liver3.33.75.9-1.8-1.6-2.2-1.1-1.2-1.22.2-2.22.22.22.2-2.22.2-0.8-2.4
Bone: minimum diameter0.40.72.10.20.20.5-0.1-0.30.0-1.11.1-1.1-1.1-1.11.1-1.0-0.41.5
Time in familiar zone, hab. session 15.04.86.1-2.1-2.2-2.3-1.9-1.8-1.92.5-2.52.52.52.5-2.52.5-1.6-1.5
Time in novel zone, hab. session 13.93.95.31.71.72.11.31.31.3-2.32.3-2.3-2.3-2.32.3-2.30.92.1
Total zone transitions, hab. session 10.40.61.6-0.7-0.9-0.3-1.3-1.1-1.20.3-0.30.30.30.3-0.30.3-1.11.2
Total locomotion distance, hab. session 11.62.25.1-1.6-1.9-1.0-2.3-2.0-2.20.9-0.90.90.90.9-0.90.9-2.21.6
Locomotion velocity, hab. session 11.72.34.9-1.7-1.9-1.2-2.2-1.9-2.21.1-1.11.11.11.1-1.11.1-2.11.1
Time in familiar zone, hab. session 25.25.57.2-2.3-2.3-2.7-1.9-1.9-1.82.6-2.62.62.62.6-2.62.6-1.6-2.0
Time in novel zone, hab. session 25.96.07.72.32.32.71.81.91.8-2.82.8-2.8-2.8-2.82.8-2.81.62.3
Total zone transitions, hab. session 20.91.24.90.60.51.20.00.0-0.0-1.31.3-1.3-1.3-1.31.3-1.3-0.32.2
Total locomotion distance, hab. session 20.30.41.2-0.6-0.8-0.2-1.1-0.9-1.10.3-0.30.30.30.3-0.30.3-1.01.0
Locomotion velocity, hab. session 20.40.61.7-0.6-0.9-0.2-1.2-1.0-1.20.3-0.30.30.30.3-0.30.3-1.21.3
Novel to familiar place preference ratio3.13.44.51.71.62.11.21.31.2-2.12.1-2.1-2.1-2.12.1-2.10.92.1
Novelty place preference2.12.33.51.31.21.70.81.00.9-1.81.8-1.8-1.8-1.81.8-1.80.61.9
Time in novel zone, NPP test2.72.94.01.51.51.91.11.21.1-2.02.0-2.0-2.0-2.02.0-2.00.91.9
Total zone transitions, NPP test0.40.61.70.80.61.10.30.40.2-0.90.9-0.9-0.9-0.90.9-0.90.41.3
Total locomotion distance, NPP test0.20.31.70.2-0.00.6-0.3-0.0-0.3-0.50.5-0.5-0.5-0.50.5-0.5-0.21.3
Locomotion velocity, NPP test0.10.21.2-0.1-0.30.3-0.6-0.3-0.6-0.10.1-0.1-0.1-0.10.1-0.1-0.41.1
Intraocular pressure0.50.83.3-0.1-0.4-0.60.00.20.11.0-1.01.01.01.0-1.01.00.7-1.8
Delta distance traveled before/after self-admin0.60.71.21.00.90.90.91.11.1-0.70.7-0.7-0.7-0.70.7-0.71.00.2
Delta ambulatory time before/after self-admin0.60.81.11.00.81.00.70.80.8-0.90.9-0.9-0.9-0.90.9-0.90.60.8
Parametrial fat weight0.41.01.30.91.01.00.90.90.9-1.11.1-1.1-1.1-1.11.1-1.10.80.8
Pavlov. Cond. lever latency0.30.41.80.30.6-0.11.00.80.90.2-0.20.20.20.2-0.20.20.9-1.3
Pavlov. Cond. magazine entry latency1.51.92.9-1.4-1.7-1.4-1.6-1.5-1.51.3-1.31.31.31.3-1.31.4-1.3-0.6
Pavlov. Cond. change in total contacts0.20.20.40.30.10.40.00.00.2-0.60.6-0.6-0.6-0.60.6-0.60.10.3
Pavlov. Cond. index score0.50.61.6-0.8-1.1-0.5-1.3-1.1-1.10.5-0.50.50.50.5-0.50.5-1.00.4
Pavlov. Cond. latency score0.60.71.9-0.8-1.2-0.5-1.4-1.3-1.30.4-0.40.40.40.4-0.40.4-1.20.7
Pavlov. Cond. lever contacts0.30.31.70.0-0.40.4-0.8-0.6-0.6-0.40.4-0.4-0.4-0.40.4-0.4-0.61.3
Pavlov. Cond. magazine entry number0.70.91.40.91.20.91.11.01.0-0.90.9-0.9-0.9-0.90.9-0.90.70.6
Pavlov. Cond. intertrial magazine entries0.10.21.0-0.2-0.0-0.40.20.20.20.4-0.40.40.40.4-0.40.40.2-1.0
Pavlov. Cond. lever-magazine prob. diff.0.60.71.7-0.8-1.2-0.6-1.3-1.2-1.20.6-0.60.60.60.6-0.60.6-1.10.3
Pavlov. Cond. response bias0.60.71.2-0.7-1.1-0.7-1.1-0.9-1.00.8-0.80.80.80.8-0.80.8-0.7-0.3
Pavlov. Cond. lever latency1.62.12.51.51.51.61.41.41.3-1.61.6-1.6-1.6-1.61.6-1.51.20.6
Pavlov. Cond. magazine entry latency2.22.73.6-1.7-1.9-1.7-1.8-1.7-1.71.7-1.71.71.71.7-1.71.7-1.4-0.6
Pavlov. Cond. change in total contacts0.71.11.5-1.1-1.0-1.2-0.8-1.1-0.91.1-1.11.11.11.1-1.11.1-0.9-0.7
Pavlov. Cond. index score1.92.63.2-1.7-1.7-1.8-1.5-1.7-1.41.7-1.71.71.71.7-1.71.7-1.4-0.8
Pavlov. Cond. latency score2.12.83.3-1.8-1.8-1.8-1.7-1.8-1.61.7-1.71.71.71.7-1.71.7-1.5-0.6
Pavlov. Cond. lever contacts1.52.12.5-1.4-1.5-1.6-1.3-1.3-1.11.6-1.61.61.61.6-1.61.6-1.1-0.9
Pavlov. Cond. magazine entry number2.32.83.81.91.91.81.81.91.7-1.61.6-1.6-1.6-1.61.6-1.61.70.5
Pavlov. Cond. intertrial magazine entries0.91.32.51.31.41.01.51.61.4-1.01.0-1.0-1.0-1.01.0-1.01.4-0.1
Pavlov. Cond. lever-magazine prob. diff.2.12.83.6-1.9-1.9-1.9-1.7-1.8-1.61.7-1.71.71.71.7-1.71.7-1.6-0.7
Pavlov. Cond. response bias2.43.24.0-1.8-1.9-2.0-1.6-1.6-1.41.9-1.91.91.91.9-1.91.9-1.4-1.2
Time in closed arm before self-admin0.20.31.30.20.20.5-0.0-0.2-0.1-0.60.6-0.6-0.6-0.60.6-0.6-0.41.2
Time in closed arm after self-admin0.50.61.30.40.70.30.80.51.1-0.90.9-0.9-0.9-0.90.9-0.90.3-0.0
Time in open arm before self-admin0.00.00.2-0.3-0.1-0.4-0.1-0.2-0.2-0.10.1-0.1-0.1-0.10.1-0.1-0.2-0.1
Time in open arm after self-admin1.51.63.01.71.51.51.51.71.2-1.11.1-1.1-1.1-1.11.1-1.11.70.1
Bone: periosteal estimation1.12.45.00.90.91.30.40.20.5-2.02.0-2.0-2.0-2.02.0-1.9-0.02.2
Bone: periosteal perimeter0.30.62.6-0.4-0.30.1-0.7-0.8-0.7-0.60.6-0.6-0.6-0.60.6-0.6-1.01.6
Bone: post-yield work0.50.70.80.80.90.80.80.90.8-0.90.9-0.9-0.9-0.90.9-0.90.80.6
Progressive ratio test 1 active lever presses0.40.51.00.60.70.40.71.00.9-0.70.7-0.7-0.7-0.70.7-0.70.40.2
Progressive ratio test 1 breakpoint0.40.51.10.60.70.40.71.00.9-0.70.7-0.7-0.7-0.70.7-0.70.50.2
Progressive ratio test 1 inactive lever presses0.10.20.7-0.8-0.5-0.9-0.4-0.5-0.30.3-0.30.30.30.3-0.30.3-0.7-0.2
Progressive ratio test 2 active lever presses0.00.10.2-0.4-0.3-0.5-0.3-0.1-0.10.1-0.10.10.10.1-0.10.1-0.5-0.0
Progressive ratio test 2 breakpoint0.10.10.3-0.5-0.4-0.6-0.5-0.2-0.20.2-0.20.20.20.2-0.20.2-0.6-0.0
Progressive ratio test 2 inactive lever presses0.20.20.60.00.20.1-0.10.20.2-0.60.6-0.6-0.6-0.60.6-0.6-0.30.7
Incentive Sensitization - Responses0.40.50.6-0.7-0.7-0.8-0.8-0.6-0.70.8-0.80.80.80.8-0.80.8-0.5-0.4
Incentive Sensitization - Breakpoint0.50.60.8-0.8-0.9-0.8-0.9-0.8-0.80.8-0.80.80.80.8-0.80.8-0.7-0.3
Sum of active levers in priming session hrs 5-60.20.10.2-0.4-0.4-0.4-0.3-0.3-0.10.4-0.40.40.40.4-0.40.4-0.1-0.4
Progressive ratio0.91.52.31.21.41.01.51.41.2-1.21.2-1.2-1.2-1.21.2-1.21.2-0.0
Food seeking constrained by brief footshock1.92.33.0-1.2-1.6-1.3-1.5-1.4-1.51.7-1.71.71.71.7-1.71.7-0.9-0.9
Seeking ratio, punishment vs. effort2.43.44.2-1.7-2.0-1.6-2.0-1.8-1.62.1-2.12.12.12.1-2.12.1-1.4-0.7
Retroperitoneal fat weight2.08.513.83.23.42.73.63.73.6-2.62.6-2.6-2.6-2.62.6-2.53.5-0.4
Reaction time number correct0.61.12.91.31.21.01.51.31.4-0.70.7-0.7-0.7-0.70.7-0.71.7-0.7
Reaction time mean minus median0.61.62.3-1.4-1.4-1.2-1.4-1.5-1.31.2-1.21.21.21.2-1.21.3-1.3-0.3
Reaction time mean minus median AUC0.71.83.8-1.5-1.6-1.0-1.9-1.9-1.70.9-0.90.90.90.9-0.91.0-1.91.0
Reaction time num false alarms0.60.91.51.11.10.91.21.20.9-0.90.9-0.9-0.9-0.90.9-0.91.10.2
Reaction time num false alarms AUC0.61.01.91.11.20.81.31.41.0-0.80.8-0.8-0.8-0.80.8-0.81.3-0.1
Reaction time trials correct on left0.61.12.91.31.21.01.51.31.4-0.70.7-0.7-0.7-0.70.7-0.71.7-0.7
Reaction time trials on left0.61.12.61.31.21.01.41.31.4-0.70.7-0.7-0.7-0.70.7-0.71.6-0.6
Reaction time mean1.01.53.1-1.3-1.5-0.9-1.7-1.8-1.51.0-1.01.01.01.0-1.01.0-1.60.6
Reaction time mean AUC0.50.71.9-0.9-1.1-0.5-1.3-1.4-1.00.5-0.50.50.50.5-0.50.6-1.20.7
Median of all reaction times0.60.92.1-1.0-1.2-0.6-1.4-1.4-1.20.7-0.70.70.70.7-0.70.7-1.30.7
Reaction time omissions0.10.10.7-0.2-0.2-0.0-0.4-0.6-0.2-0.30.3-0.3-0.3-0.30.3-0.3-0.60.8
Reaction time false alarm rate0.20.20.40.50.50.50.40.60.3-0.50.5-0.5-0.5-0.50.5-0.50.40.5
Reaction time premature initiation rate1.52.13.2-1.2-1.0-1.5-0.7-0.5-0.91.8-1.81.81.81.8-1.81.7-0.6-1.5
Reaction time premature initiations0.71.33.7-0.5-0.3-1.00.10.2-0.11.4-1.41.41.41.4-1.41.40.3-1.9
Std. dev. reaction times0.51.01.9-1.1-1.2-0.9-1.3-1.4-1.20.8-0.80.80.80.8-0.80.8-1.30.4
Reaction time trials completed0.61.12.61.31.21.01.41.31.4-0.70.7-0.7-0.7-0.70.7-0.71.6-0.6
Reaction time trials AUC0.71.33.41.41.31.11.61.41.5-0.70.7-0.7-0.7-0.70.7-0.71.8-0.8
Run reversals in cocaine runway, females2.72.74.4-1.8-1.9-1.5-2.1-1.9-2.11.5-1.51.51.51.5-1.51.5-1.90.2
Run reversals in cocaine runway, males2.22.24.1-1.8-1.8-1.5-1.9-2.0-1.61.2-1.21.21.21.2-1.21.2-2.00.1
Latency to leave start box in cocaine runway0.30.42.60.30.10.6-0.3-0.0-0.3-0.60.6-0.6-0.6-0.60.6-0.4-0.31.6
Latency to leave start box in cocaine runway, F0.60.74.30.30.10.9-0.4-0.2-0.4-0.80.8-0.8-0.8-0.80.8-0.5-0.52.1
Latency to leave start box in cocaine runway, M0.00.00.10.10.2-0.10.30.30.30.1-0.10.10.10.1-0.10.10.3-0.4
Std. dev. time between licks in bursts0.60.92.2-1.1-1.2-0.8-1.3-1.4-1.20.5-0.50.50.50.5-0.50.5-1.50.9
Total sessions with >9 infusions0.70.81.40.10.80.10.70.40.9-1.21.2-1.2-1.2-1.21.2-1.2-0.30.7
Short access day 1 total inactive lever presses0.40.51.0-0.7-0.6-1.0-0.3-0.4-0.40.8-0.80.80.80.8-0.80.8-0.3-0.9
Short access day 10 total inactive lever presses0.20.63.0-0.4-0.1-0.90.40.10.20.8-0.80.80.80.8-0.80.80.4-1.7
Short access day 1 total infusions0.60.91.40.10.80.10.80.30.8-1.21.2-1.2-1.2-1.21.2-1.2-0.30.7
Short access day 10 total infusions0.20.30.40.20.60.10.60.30.6-0.60.6-0.6-0.6-0.60.6-0.60.10.3
Short access total infusions1.01.32.10.41.00.50.90.61.0-1.51.5-1.5-1.5-1.51.5-1.5-0.00.9
Short access day 1 locomotion0.40.51.6-1.1-0.5-1.2-0.2-0.5-0.30.6-0.60.60.60.6-0.60.6-0.9-0.5
Short access day 10 total locomotion1.42.65.3-1.9-1.1-2.3-0.6-0.8-0.91.8-1.81.81.81.8-1.81.8-1.0-1.9
Short access total locomotion0.30.41.4-1.0-0.4-1.2-0.2-0.2-0.10.6-0.60.60.60.6-0.60.6-0.7-0.7
One hour access (0.3 mA shock)0.10.10.30.30.40.10.40.50.5-0.30.3-0.3-0.3-0.30.3-0.30.4-0.4
Compulsive drug intake0.00.00.1-0.1-0.2-0.0-0.3-0.2-0.20.1-0.10.10.10.1-0.10.1-0.20.1
One hour access (shock baseline)0.00.00.2-0.3-0.1-0.50.0-0.0-0.00.2-0.20.20.20.2-0.20.2-0.2-0.3
Social response proportion0.91.01.7-0.9-0.9-0.7-1.0-1.0-1.31.1-1.11.11.11.1-1.11.1-1.10.1
Social responses8.410.813.1-3.5-3.5-3.2-3.5-3.4-3.63.4-3.43.43.43.4-3.43.4-3.4-0.4
Social time1.01.42.01.41.31.31.41.31.3-1.01.0-1.0-1.0-1.01.0-1.01.4-0.0
Soleus weight5.917.221.14.64.54.54.24.24.3-4.24.2-4.2-4.2-4.24.2-4.24.11.7
Bone: stiffness3.96.48.42.42.52.72.01.92.0-2.92.9-2.9-2.9-2.92.9-2.91.52.1
Tibialis anterior weight1.34.55.62.42.32.32.22.12.2-2.12.1-2.1-2.1-2.12.1-2.12.00.8
Time to tail flick, vehicle, before self-admin0.91.02.3-1.3-1.2-1.0-1.3-1.4-0.90.7-0.70.70.70.7-0.70.7-1.50.3
Time to tail flick, vehicle, after self-admin0.60.82.2-0.4-0.4-0.7-0.1-0.3-0.31.1-1.11.11.11.1-1.11.10.4-1.5
Time to tail flick, test, before self-admin0.70.71.8-1.0-1.0-0.6-1.2-1.3-1.30.3-0.30.30.30.3-0.30.3-1.31.0
Time to tail flick, test, after self-admin0.10.10.3-0.1-0.00.0-0.2-0.2-0.0-0.30.3-0.3-0.3-0.30.3-0.3-0.30.6
Delta time to tail flick, vehicle, before/after SA1.11.14.11.51.21.01.41.51.1-0.40.4-0.4-0.4-0.40.4-0.42.0-1.0
Delta time to tail flick, test, before/after SA0.30.31.60.30.3-0.00.50.60.70.3-0.30.30.30.3-0.30.30.8-1.3
Tibia length0.92.53.4-1.5-1.6-1.6-1.3-1.1-1.41.8-1.81.81.81.8-1.81.8-1.0-1.1
Ambulatory time before self-admin0.30.50.6-0.8-0.7-0.8-0.7-0.6-0.70.7-0.70.70.70.7-0.70.7-0.6-0.4
Ambulatory time after self-admin0.00.00.10.20.10.10.10.30.20.0-0.00.00.00.0-0.00.00.10.1
Bone: tissue strength5.65.67.02.32.42.42.12.12.1-2.62.6-2.6-2.6-2.62.6-2.61.71.6
Total heroin consumption2.12.43.4-1.6-1.8-1.5-1.8-1.6-1.71.6-1.61.61.61.6-1.61.6-1.5-0.2
Bone: trabecular number0.40.61.5-0.8-0.8-0.4-1.2-1.1-1.10.3-0.30.30.30.3-0.30.3-1.21.2
Bone: trabecular spacing0.60.84.70.50.6-0.11.21.21.20.2-0.20.20.20.2-0.20.31.3-2.2
Bone: trabecular thickness1.51.911.3-0.0-0.10.9-0.9-1.1-1.0-1.31.3-1.3-1.3-1.31.3-1.3-1.33.4
Bone: trabecular tissue density4.46.48.32.72.92.52.92.72.8-2.52.5-2.5-2.5-2.52.5-2.52.70.3
Water consumed over 24 hours0.71.01.70.80.91.10.60.60.5-1.21.2-1.2-1.2-1.21.2-1.20.41.3
Number of responses in last shaping day2.12.34.8-1.9-1.3-2.2-1.0-1.3-1.01.5-1.51.51.51.5-1.51.5-1.5-1.2