Hub : Genes

Itga7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Itga7 0.29 0.15 8.0e-05 0.15 0.17 0.17 0.17 2.2e-04 6.9e-05 6.4e-05 9.3e-05
2 Adipose intron excision ratio chr7_1368521_1369391 0.04 0.03 7.6e-04 0.02 0.02 0.02 0.02 3.5e-03 2.6e-03 1.8e-03 4.7e-03
3 NAcc intron excision ratio chr7_1367507_1368019 0.04 0.03 1.5e-04 0.04 0.02 0.03 0.03 5.8e-05 8.3e-04 2.8e-04 2.9e-04
4 NAcc gene expression Itga7 0.2 0.1 0.0e+00 0.23 0.21 0.22 0.22 2.9e-26 9.5e-24 2.2e-25 1.4e-25
5 BLA gene expression Itga7 0.13 0.09 3.7e-07 0.12 0.11 0.11 0.12 3.6e-07 2.2e-06 1.6e-06 4.2e-07
6 Adipose intron excision ratio chr7_1367507_1368402 0.06 0.04 4.7e-05 0.04 0.04 0.04 0.04 1.2e-05 3.7e-05 3.2e-05 1.8e-05
7 Liver mRNA stability Itga7 0.04 0.03 9.0e-04 0.02 0.02 0.02 0.02 1.4e-03 3.3e-03 6.4e-03 3.9e-03
8 Adipose intron excision ratio chr7_1367507_1368019 0.06 0.04 6.7e-05 0.04 0.04 0.04 0.04 1.6e-05 5.0e-05 3.9e-05 2.5e-05
9 Adipose intron excision ratio chr7_1368150_1369391 0.04 0.03 7.4e-04 0.02 0.02 0.02 0.02 1.4e-03 2.5e-03 1.8e-03 4.3e-03
10 pVTA gene expression Itga7 0.09 0.06 1.5e-03 0.01 0.04 0.04 0.03 9.4e-02 8.5e-03 6.1e-03 2.3e-02
11 Adipose gene expression Itga7 0.27 0.14 0.0e+00 0.17 0.17 0.17 0.17 2.7e-18 2.9e-18 1.9e-18 1.2e-18

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.50.81.6-0.00.31.11.01.00.80.8-0.8-0.81.2-1.3
Area under the delay curve0.00.00.1-0.10.0-0.3-0.1-0.2-0.1-0.10.10.10.0-0.2
BMI with tail7.524.427.8-5.35.2-4.8-4.7-4.85.15.1-5.1-5.1-4.3-4.8
BMI without tail1.53.13.9-1.91.8-2.0-2.0-1.91.61.6-1.6-1.6-2.0-1.4
Body weight1.35.56.7-2.52.4-2.6-2.5-2.62.32.3-2.3-2.3-2.2-2.1
Weight adjusted by age0.10.10.3-0.1-0.0-0.2-0.6-0.3-0.2-0.20.20.2-0.40.3
Bone surface1.32.35.50.5-0.02.32.12.10.90.9-0.9-0.92.3-1.5
Bone volume1.32.14.70.20.22.01.91.91.11.1-1.1-1.12.2-1.7
Breakpoint value in progressive ratio session2.02.22.91.6-1.61.21.11.2-1.7-1.71.71.70.91.7
Number of licking bursts3.54.16.3-2.02.0-2.5-2.4-2.51.71.7-1.7-1.7-2.3-1.4
Context. condit. distance diff. score0.20.30.3-0.50.5-0.6-0.5-0.50.50.5-0.5-0.5-0.5-0.4
Locomotion velocity, session 10.20.20.6-0.30.3-0.00.10.10.50.5-0.5-0.50.4-0.7
Locomotion distance, session 10.30.41.40.4-0.30.91.01.00.10.1-0.1-0.11.2-0.4
Locomotion velocity, session 21.41.64.41.2-1.01.91.71.7-0.5-0.50.50.52.10.2
Locomotion distance, session 22.43.45.92.0-1.92.22.42.1-1.4-1.41.41.42.41.0
Locomotion velocity, session 34.95.86.52.6-2.62.22.32.1-2.5-2.52.52.52.22.4
Locomotion distance, session 30.10.10.20.3-0.30.10.30.0-0.4-0.40.40.40.10.4
Stereotopy head waving bouts, day 36.07.08.72.8-2.72.92.82.8-2.5-2.52.52.52.72.3
Stereotopy head waving duration, day 34.04.76.72.2-2.12.62.42.6-1.9-1.91.91.92.41.7
Locomotion velocity, session 70.10.10.40.3-0.20.40.60.6-0.1-0.10.10.10.6-0.0
Locomotion distance, session 70.10.10.4-0.20.2-0.6-0.4-0.40.10.1-0.1-0.1-0.70.1
Stereotopy head waving bouts, day 70.91.02.11.0-0.91.31.31.2-0.7-0.70.70.71.40.4
Stereotopy head waving duration, day 70.70.82.30.9-0.91.11.21.1-0.6-0.60.60.61.50.2
Locomotion velocity, session 81.21.43.71.2-1.21.51.51.5-0.8-0.80.80.81.90.4
Locomotion distance, session 80.30.40.70.8-0.70.60.70.6-0.6-0.60.60.60.80.4
Degree of sensitization distance0.60.60.7-0.80.8-0.8-0.7-0.50.80.8-0.8-0.8-0.6-0.8
Degree of sensitization stereotypy0.10.10.3-0.30.2-0.10.0-0.20.40.4-0.4-0.40.2-0.6
Conditioned locomotion1.11.33.2-1.20.9-1.7-1.6-1.60.50.5-0.5-0.5-1.8-0.3
Cocaine response after cond. corrected2.22.54.4-1.61.5-2.0-1.9-2.11.21.2-1.2-1.2-2.0-0.9
Cocaine response after cond. not corrected2.32.54.3-1.61.5-2.0-2.1-2.11.21.2-1.2-1.2-2.1-0.8
Cocaine response before conditioning0.50.61.20.7-0.81.10.91.0-0.7-0.70.70.70.90.6
Saline control response0.40.51.0-0.80.7-0.8-0.8-1.00.60.6-0.6-0.6-0.9-0.5
Bone: connectivity density0.30.50.90.00.20.90.80.90.60.6-0.6-0.61.0-0.9
Bone: cortical apparent density1.52.02.3-1.41.5-1.2-1.3-1.21.51.5-1.5-1.5-1.2-1.4
Bone: cortical area1.21.83.9-1.11.4-0.1-0.1-0.11.81.8-1.8-1.80.1-2.0
Bone: cortical porosity0.10.20.50.20.00.70.50.50.20.2-0.2-0.20.7-0.3
Bone: cortical porosity0.40.40.9-0.30.50.50.30.30.80.8-0.8-0.80.5-0.9
Bone: cortical thickness1.52.53.9-1.61.8-0.8-0.9-0.81.91.9-1.9-1.9-0.7-2.0
Bone: cortical thickness0.80.91.4-1.11.0-1.2-0.8-1.10.90.9-0.9-0.9-1.1-0.7
Bone: cortical tissue density1.11.41.6-1.21.3-1.0-1.1-1.01.31.3-1.3-1.3-1.1-1.2
Condit. Reinf. active minus inactive responses2.02.32.91.7-1.51.61.71.6-1.4-1.41.41.41.61.3
Condit. Reinf. active-inactive response ratio0.30.30.40.6-0.50.50.40.5-0.6-0.60.60.60.30.6
Condit. Reinf. active responses2.93.65.62.1-1.82.22.42.2-1.5-1.51.51.52.31.3
Condit. Reinf. inactive responses1.51.83.51.4-1.31.61.81.7-1.0-1.01.01.01.90.7
Incentive salience index mean1.31.62.81.4-1.21.51.61.5-0.9-0.90.90.91.70.7
Condit. Reinf. lever presses0.30.51.90.6-0.40.91.00.9-0.0-0.00.00.01.4-0.3
Condit. Reinf. active minus inactive responses2.12.63.71.6-1.61.31.21.4-1.8-1.81.81.81.01.9
Condit. Reinf. active-inactive response ratio0.80.92.20.7-0.90.10.10.1-1.2-1.21.21.2-0.21.5
Condit. Reinf. active responses1.42.02.51.4-1.41.61.41.5-1.4-1.41.41.41.31.3
Condit. Reinf. inactive responses0.40.41.10.7-0.51.00.90.9-0.3-0.30.30.31.00.2
Condit. Reinf. lever presses2.73.74.81.9-2.01.71.41.6-2.2-2.22.22.21.22.2
Condit. Reinf. lever reinforcers received1.01.51.71.2-1.21.21.11.1-1.3-1.31.31.30.91.3
Conditioned reinforcement - actives0.30.31.10.00.11.10.71.00.30.3-0.3-0.30.5-0.5
Conditioned reinforcement - inactives1.21.32.2-1.31.3-0.9-1.5-0.91.01.0-1.0-1.0-1.5-0.8
Conditioned locomotion2.83.36.61.8-1.62.51.92.6-1.5-1.51.51.51.91.3
Patch foraging indifference point 0 sec3.86.27.6-2.62.7-1.9-2.1-2.02.82.8-2.8-2.8-1.9-2.7
Patch foraging indifference point AUC0.60.70.91.0-0.90.50.60.6-0.9-0.90.90.90.70.9
Delay disc. indifference point, 0s delay1.21.33.2-1.01.2-0.8-0.6-0.71.41.4-1.4-1.4-0.0-1.8
Delay disc. indifference point, 16s delay0.40.40.50.6-0.60.40.60.5-0.7-0.70.70.70.60.5
Delay disc. indifference point, 2s delay0.20.20.5-0.30.4-0.6-0.3-0.50.50.5-0.5-0.5-0.0-0.7
Delay disc. indifference point, 24s delay0.30.30.6-0.60.4-0.8-0.8-0.70.30.3-0.3-0.3-0.6-0.4
Delay disc. indifference point, 4s delay0.40.40.90.6-0.60.70.80.7-0.5-0.50.50.51.00.1
Delay disc. indifference point, 8s delay0.20.20.6-0.30.2-0.7-0.7-0.8-0.2-0.20.20.2-0.70.1
Indifference point function ln k0.20.20.4-0.50.6-0.3-0.1-0.20.60.6-0.6-0.6-0.4-0.5
Indifference point function log k0.20.20.4-0.50.6-0.3-0.1-0.20.60.6-0.6-0.6-0.4-0.5
Patch foraging total patch changes 0 sec3.55.76.9-2.52.6-1.9-2.0-2.02.62.6-2.6-2.6-1.9-2.5
Patch foraging total patch changes 12 sec1.92.43.9-1.61.6-1.6-2.0-1.81.41.4-1.4-1.4-1.8-1.2
Patch foraging total patch changes 18 sec0.00.00.1-0.20.1-0.2-0.4-0.20.10.1-0.1-0.1-0.2-0.1
Patch foraging total patch changes 24 sec0.60.71.0-0.90.8-0.6-1.0-0.70.90.9-0.9-0.9-0.7-0.9
Patch foraging total patch changes 6 sec2.02.93.7-1.81.9-1.3-1.4-1.41.91.9-1.9-1.9-1.3-1.8
Patch foraging time to switch 0 sec0.20.30.7-0.60.6-0.1-0.5-0.40.70.7-0.7-0.7-0.1-0.8
Patch foraging water rate 0 sec0.50.91.9-0.90.9-1.2-1.1-1.10.70.7-0.7-0.7-1.4-0.4
Patch foraging water rate 12 sec0.81.22.6-1.11.1-1.5-1.3-1.30.80.8-0.8-0.8-1.6-0.5
Patch foraging water rate 18 sec0.40.51.4-0.1-0.0-0.9-0.7-0.8-0.5-0.50.50.5-1.20.9
Patch foraging water rate 24 sec1.72.46.7-1.41.1-2.4-2.1-2.30.50.5-0.5-0.5-2.6-0.0
Patch foraging water rate 6 sec0.40.61.50.7-0.70.20.30.3-0.9-0.90.90.9-0.21.2
Seeking ratio, delayed vs. immediate footshock1.41.63.21.2-1.11.81.71.8-0.8-0.80.80.81.50.7
Distance traveled before self-admin0.91.01.31.1-1.11.01.10.9-1.0-1.01.01.01.00.9
Distance traveled after self-admin0.20.20.60.4-0.40.80.40.7-0.4-0.40.40.40.50.3
Extensor digitorum longus weight5.521.626.8-5.04.8-5.0-5.1-5.24.34.3-4.3-4.3-4.9-3.8
Bone: elastic displacement0.00.00.00.00.00.20.20.20.10.1-0.1-0.10.1-0.1
Bone: elastic work0.70.81.5-0.91.0-0.5-0.5-0.61.11.1-1.1-1.1-0.4-1.2
Bone: endosteal estimation0.71.52.7-1.11.4-0.4-0.2-0.41.61.6-1.6-1.6-0.4-1.7
Bone: endosteal perimeter0.40.82.20.7-0.41.41.51.3-0.1-0.10.10.11.4-0.1
Epididymis fat weight0.10.20.40.4-0.5-0.0-0.10.2-0.6-0.60.60.60.00.6
Delta time in closed arm before/after self-admin1.01.02.7-0.90.8-1.4-1.5-1.40.30.3-0.3-0.3-1.70.1
Delta time in open arm before/after self-admin1.51.41.6-1.21.1-1.2-1.2-1.31.21.2-1.2-1.2-1.1-1.2
Diff in mean of infusions in LGA sessions2.12.42.61.6-1.61.51.41.6-1.6-1.61.61.61.31.5
Delay discount exponential model param0.00.00.10.00.00.30.10.20.20.2-0.2-0.2-0.00.1
Extinction: sum of active levers before priming3.33.35.51.8-2.00.91.10.9-2.2-2.22.22.20.82.3
Active lever presses in extinction session 61.11.11.41.2-1.20.91.00.9-1.1-1.11.11.11.01.0
Bone: final force2.84.57.1-2.22.3-1.2-1.3-1.32.52.5-2.5-2.5-1.1-2.7
Bone: final moment2.64.36.9-2.22.2-1.2-1.3-1.22.52.5-2.5-2.5-1.0-2.6
Food consumed during 24 hour testing period0.40.50.6-0.80.7-0.6-0.8-0.70.70.7-0.7-0.7-0.6-0.7
Glucose2.03.03.4-1.81.8-1.8-1.8-1.81.71.7-1.7-1.7-1.6-1.6
Heart weight0.00.00.0-0.10.1-0.2-0.2-0.10.10.1-0.1-0.1-0.2-0.0
Delay discount hyperbolic model param0.00.10.20.2-0.20.50.20.4-0.0-0.00.00.00.10.3
Intermittent access intake day 1-15 change0.30.30.90.5-0.40.90.40.7-0.4-0.40.40.40.30.5
Intermittent access intake escalation0.20.20.60.2-0.20.3-0.30.0-0.5-0.50.50.5-0.30.8
Intermittent access intake escalation 20.70.71.40.7-0.80.60.30.4-1.0-1.01.01.00.21.2
Intermitt. access day 1 inactive lever presses0.10.20.50.1-0.1-0.0-0.4-0.0-0.5-0.50.50.5-0.40.7
Intermitt. access day 15 inactive lever presses0.80.91.70.9-0.90.70.50.5-1.2-1.21.21.20.31.3
Intermitt. access escalation Index0.60.51.70.20.11.30.81.10.40.4-0.4-0.40.9-0.6
Intermittent access day 1 total infusions0.40.40.7-0.70.7-0.3-0.4-0.20.80.8-0.8-0.8-0.6-0.8
Intermittent access day 15 total infusions0.20.20.4-0.50.50.0-0.5-0.10.40.4-0.4-0.4-0.7-0.3
Intermittent access terminal intake (last 3 days)0.30.30.6-0.50.60.3-0.10.30.80.8-0.8-0.8-0.3-0.8
Intermittent access total infusions0.50.50.7-0.80.8-0.3-0.6-0.40.80.8-0.8-0.8-0.9-0.7
Intermittent access day 1 locomotion0.00.00.2-0.10.0-0.1-0.40.0-0.0-0.00.00.0-0.30.0
Intermittent access day 15 total locomotion0.30.40.90.5-0.51.00.31.0-0.5-0.50.50.50.30.6
Intermittent access total locomotion0.20.20.50.4-0.50.70.20.7-0.4-0.40.40.40.30.4
Intermittent access standard deviation0.10.10.40.3-0.20.60.20.5-0.3-0.30.30.30.20.4
Left kidney weight0.20.41.2-0.30.50.20.30.40.80.8-0.8-0.80.5-1.1
Right kidney weight0.30.81.80.8-0.61.21.21.3-0.4-0.40.40.41.30.2
Cocaine induced anxiety1.51.73.31.4-1.31.51.51.6-1.1-1.11.11.11.80.8
Post-drug Anxiety0.50.51.90.6-0.51.11.01.1-0.1-0.10.10.11.4-0.3
Baseline Anxiety0.00.00.2-0.10.1-0.3-0.2-0.30.00.0-0.0-0.0-0.40.1
Tail length4.613.816.93.9-4.03.23.13.2-4.1-4.14.14.12.64.1
Length with tail1.65.76.82.6-2.62.22.22.2-2.5-2.52.52.52.12.4
Length without tail0.10.30.7-0.40.5-0.00.0-0.10.70.7-0.7-0.70.4-0.9
Times rat made contact with spout1.11.32.1-1.21.1-1.4-1.4-1.30.90.9-0.9-0.9-1.5-0.7
Lifetime Intake1.21.42.0-1.21.3-0.3-0.8-0.41.41.4-1.4-1.4-1.0-1.4
Liver weight, left1.52.42.8-1.71.7-1.7-1.6-1.51.51.5-1.5-1.5-1.6-1.3
Liver weight, right0.91.52.0-1.41.4-1.0-1.3-0.81.31.3-1.3-1.3-0.9-1.3
Locomotor activity3.35.26.72.3-2.32.42.52.6-2.1-2.12.12.12.51.8
Locomotor testing distance1.32.13.11.5-1.41.61.71.8-1.3-1.31.31.31.71.1
Locomotor testing rearing0.00.10.1-0.1-0.1-0.2-0.2-0.2-0.3-0.30.30.3-0.20.3
Locomotion in novel chamber0.20.30.4-0.60.6-0.2-0.5-0.30.60.6-0.6-0.6-0.4-0.5
Locomotion in novel chamber post-restriction3.54.24.92.2-2.21.72.02.0-2.1-2.12.12.11.82.0
Fecal boli incidents, locomotor time 10.80.92.1-0.90.7-1.5-1.3-1.40.40.4-0.4-0.4-1.4-0.2
Change in fecal boli incidents, locomotor task0.70.61.90.8-0.51.21.21.1-0.0-0.00.00.01.4-0.0
Time >=10cm from walls, locomotor time 10.60.61.4-0.80.8-0.3-0.3-0.30.90.9-0.9-0.9-0.1-1.2
Bouts of movement, locomotor time 10.60.71.00.8-0.80.80.60.6-1.0-1.01.01.00.60.8
Total resting periods, locomotor time 11.31.51.91.2-1.21.11.01.0-1.4-1.41.41.41.01.1
Rest time, locomotor task time 10.50.50.60.7-0.80.70.70.7-0.8-0.80.80.80.70.5
Distance moved, locomotor task time 11.01.12.0-0.81.0-0.2-0.3-0.21.41.4-1.4-1.4-0.1-1.3
Vertical activity count, locomotor time 11.31.31.8-1.21.3-0.8-1.0-0.81.31.3-1.3-1.3-0.9-1.1
Time >=10cm from walls, locomotor time 21.11.21.8-1.21.1-1.2-1.3-1.20.90.9-0.9-0.9-1.2-0.8
Bouts of movement, locomotor time 20.50.51.10.5-0.51.01.00.8-0.6-0.60.60.61.00.0
Total resting periods, locomotor time 20.40.51.20.5-0.41.11.00.9-0.4-0.40.40.41.1-0.1
Rest time, locomotor task time 20.10.10.20.1-0.20.40.30.4-0.0-0.00.00.00.5-0.2
Distance moved, locomotor task time 20.10.10.4-0.30.2-0.4-0.5-0.40.10.1-0.1-0.1-0.70.2
Vertical activity count, locomotor time 21.41.62.8-1.31.2-1.5-1.6-1.60.90.9-0.9-0.9-1.7-0.6
Light reinforcement 13.46.37.82.6-2.62.82.52.8-2.4-2.42.42.42.42.2
Light reinforcement 21.01.31.81.1-1.11.31.21.3-1.1-1.11.11.11.11.0
Bone: marrow area0.61.32.4-1.01.3-0.4-0.2-0.41.51.5-1.5-1.5-0.3-1.6
Bone: maximum diameter0.61.02.80.7-0.41.61.71.50.00.0-0.0-0.01.6-0.4
Bone: maximum force2.95.07.5-2.42.5-1.4-1.4-1.52.72.7-2.7-2.7-1.2-2.7
Bone: maximum moment2.84.97.4-2.32.4-1.3-1.4-1.52.62.6-2.6-2.6-1.2-2.7
Mean time between licks in bursts0.81.11.51.2-1.10.91.01.0-1.1-1.11.11.10.51.1
Mean num. licks in bursts0.81.01.50.9-1.01.21.01.2-0.9-0.90.90.91.00.8
Cd content in liver0.30.40.7-0.50.6-0.6-0.5-0.80.60.6-0.6-0.6-0.2-0.7
Co content in liver1.11.31.91.2-1.20.90.80.8-1.3-1.31.31.30.71.4
Cu content in liver1.21.53.0-1.11.3-0.4-0.6-0.21.61.6-1.6-1.6-0.1-1.7
Fe content in liver0.50.61.1-0.80.8-0.8-1.0-0.80.60.6-0.6-0.6-1.0-0.5
K content in liver0.60.61.70.7-0.71.31.01.2-0.5-0.50.50.51.10.3
Mg content in liver0.50.51.40.7-0.51.01.20.8-0.3-0.30.30.31.10.0
Mn content in liver0.91.13.30.7-0.51.71.61.50.10.1-0.1-0.11.8-0.5
Na content in liver0.10.10.2-0.30.2-0.2-0.4-0.20.30.3-0.3-0.3-0.1-0.4
Rb content in liver0.81.02.1-0.81.00.40.10.21.31.3-1.3-1.30.3-1.5
Se content in liver0.00.10.10.2-0.20.40.10.3-0.2-0.20.20.20.20.1
Sr content in liver0.20.20.60.3-0.30.1-0.10.1-0.5-0.50.50.5-0.40.8
Zn content in liver2.12.34.71.4-1.60.50.50.6-1.9-1.91.91.90.22.2
Bone: minimum diameter0.40.71.7-0.50.80.30.40.21.11.1-1.1-1.10.3-1.3
Time in familiar zone, hab. session 15.34.96.22.3-2.41.81.71.8-2.5-2.52.52.51.52.5
Time in novel zone, hab. session 13.73.65.9-1.92.1-1.2-1.1-1.22.32.3-2.3-2.3-0.8-2.4
Total zone transitions, hab. session 10.40.61.90.8-0.71.01.01.0-0.4-0.40.40.41.40.1
Total locomotion distance, hab. session 11.82.56.21.6-1.42.22.12.2-0.9-0.90.90.92.50.4
Locomotion velocity, hab. session 11.82.65.51.7-1.52.12.02.1-1.1-1.11.11.12.30.7
Time in familiar zone, hab. session 25.15.26.92.4-2.41.91.91.8-2.6-2.62.62.61.52.6
Time in novel zone, hab. session 25.65.67.9-2.42.5-1.9-1.9-1.72.72.7-2.7-2.7-1.4-2.8
Total zone transitions, hab. session 20.60.82.1-0.70.8-0.1-0.1-0.11.21.2-1.2-1.20.4-1.5
Total locomotion distance, hab. session 20.30.41.30.7-0.60.80.90.9-0.3-0.30.30.31.20.0
Locomotion velocity, hab. session 20.40.61.90.7-0.60.91.11.0-0.3-0.30.30.31.4-0.1
Novel to familiar place preference ratio3.03.15.0-1.71.8-1.1-1.3-1.22.12.1-2.1-2.1-0.7-2.2
Novelty place preference2.02.03.6-1.41.5-0.8-1.0-0.91.71.7-1.7-1.7-0.4-1.9
Time in novel zone, NPP test2.62.74.4-1.61.7-1.0-1.2-1.22.02.0-2.0-2.0-0.6-2.1
Total zone transitions, NPP test0.30.40.8-0.60.6-0.5-0.6-0.60.80.8-0.8-0.8-0.1-0.9
Total locomotion distance, NPP test0.10.10.5-0.10.20.10.10.00.50.5-0.5-0.50.4-0.7
Locomotion velocity, NPP test0.10.10.40.2-0.20.40.40.30.10.1-0.1-0.10.7-0.3
Intraocular pressure0.60.81.90.7-0.9-0.10.0-0.1-1.2-1.21.21.2-0.31.4
Delta distance traveled before/after self-admin0.00.00.1-0.30.20.1-0.20.20.30.3-0.3-0.3-0.1-0.3
Delta ambulatory time before/after self-admin0.10.10.3-0.20.30.20.00.30.40.4-0.4-0.40.1-0.5
Parametrial fat weight0.00.10.20.3-0.30.00.00.0-0.4-0.40.40.40.00.4
Pavlov. Cond. lever latency0.20.21.0-0.40.2-0.5-0.7-0.6-0.1-0.10.10.1-1.00.4
Pavlov. Cond. magazine entry latency1.62.02.51.6-1.51.21.31.3-1.5-1.51.51.51.21.5
Pavlov. Cond. change in total contacts0.20.20.3-0.30.5-0.2-0.1-0.20.60.6-0.6-0.6-0.1-0.6
Pavlov. Cond. index score0.50.61.40.9-0.70.91.00.9-0.5-0.50.50.51.20.3
Pavlov. Cond. latency score0.60.72.00.9-0.71.11.11.1-0.4-0.40.40.41.40.2
Pavlov. Cond. lever contacts0.20.21.00.2-0.00.40.50.40.30.3-0.3-0.31.0-0.6
Pavlov. Cond. magazine entry number0.50.70.9-1.00.9-0.7-0.7-0.80.80.8-0.8-0.8-0.8-0.8
Pavlov. Cond. intertrial magazine entries0.10.10.30.2-0.2-0.20.0-0.1-0.4-0.40.40.4-0.30.6
Pavlov. Cond. lever-magazine prob. diff.0.60.81.71.0-0.81.01.11.1-0.6-0.60.60.61.30.5
Pavlov. Cond. response bias0.70.91.21.1-1.00.80.80.9-0.9-0.90.90.91.00.9
Pavlov. Cond. lever latency1.52.12.4-1.51.6-1.4-1.3-1.31.51.5-1.5-1.5-1.2-1.4
Pavlov. Cond. magazine entry latency2.42.83.21.8-1.71.81.71.7-1.6-1.61.61.61.51.5
Pavlov. Cond. change in total contacts0.71.01.21.0-1.01.11.01.0-1.0-1.01.01.00.81.0
Pavlov. Cond. index score2.12.73.01.7-1.71.71.61.6-1.7-1.71.71.71.41.6
Pavlov. Cond. latency score2.22.83.11.8-1.71.71.71.7-1.7-1.71.71.71.51.5
Pavlov. Cond. lever contacts1.41.82.31.4-1.41.31.11.1-1.5-1.51.51.50.91.5
Pavlov. Cond. magazine entry number2.22.73.3-1.71.7-1.8-1.8-1.71.51.5-1.5-1.5-1.6-1.4
Pavlov. Cond. intertrial magazine entries1.01.22.2-1.21.1-1.3-1.5-1.30.90.9-0.9-0.9-1.3-0.7
Pavlov. Cond. lever-magazine prob. diff.2.22.83.31.8-1.71.81.81.7-1.6-1.61.61.61.51.5
Pavlov. Cond. response bias2.22.93.41.8-1.81.71.61.5-1.8-1.81.81.81.31.8
Time in closed arm before self-admin0.20.30.7-0.30.40.00.10.00.70.7-0.7-0.70.2-0.9
Time in closed arm after self-admin0.30.30.5-0.50.7-0.2-0.3-0.20.70.7-0.7-0.7-0.3-0.6
Time in open arm before self-admin0.30.40.60.6-0.40.80.70.8-0.5-0.50.50.50.50.6
Time in open arm after self-admin1.11.31.9-1.21.1-1.3-1.3-1.30.90.9-0.9-0.9-1.4-0.8
Bone: periosteal estimation1.22.55.3-1.31.7-0.2-0.1-0.32.12.1-2.1-2.1-0.0-2.3
Bone: periosteal perimeter0.40.61.1-0.00.31.01.00.90.70.7-0.7-0.71.0-1.0
Bone: post-yield work0.40.50.7-0.80.8-0.5-0.5-0.60.80.8-0.8-0.8-0.5-0.8
Progressive ratio test 1 active lever presses1.61.72.5-1.41.4-0.9-1.6-0.91.31.3-1.3-1.3-1.4-1.2
Progressive ratio test 1 breakpoint1.71.82.5-1.51.4-0.9-1.6-0.91.41.4-1.4-1.4-1.4-1.3
Progressive ratio test 1 inactive lever presses0.20.20.7-0.10.30.80.30.80.40.4-0.4-0.40.1-0.4
Progressive ratio test 2 active lever presses0.60.70.9-0.90.9-0.2-0.6-0.31.01.0-1.0-1.0-0.7-0.9
Progressive ratio test 2 breakpoint0.30.30.7-0.40.60.4-0.00.30.80.8-0.8-0.8-0.1-0.8
Progressive ratio test 2 inactive lever presses0.40.50.9-0.70.80.3-0.40.10.90.9-0.9-0.9-0.4-0.9
Incentive Sensitization - Responses0.10.10.40.3-0.20.70.50.5-0.2-0.20.20.20.40.2
Incentive Sensitization - Breakpoint0.20.20.70.4-0.30.90.70.7-0.2-0.20.20.20.60.2
Sum of active levers in priming session hrs 5-60.30.30.40.6-0.60.40.40.4-0.6-0.60.60.60.30.6
Progressive ratio1.21.41.7-1.31.3-1.0-1.3-1.11.21.2-1.2-1.2-1.2-1.1
Food seeking constrained by brief footshock1.82.22.81.6-1.70.91.31.0-1.7-1.71.71.71.11.6
Seeking ratio, punishment vs. effort2.53.13.91.9-2.01.21.71.3-1.9-1.91.91.91.41.8
Retroperitoneal fat weight2.58.310.3-3.13.0-2.9-3.2-3.02.82.8-2.8-2.8-2.9-2.5
Reaction time number correct1.01.42.7-1.21.0-1.6-1.5-1.70.70.7-0.7-0.7-1.6-0.5
Reaction time mean minus median1.31.72.11.5-1.41.31.41.3-1.3-1.31.31.31.31.2
Reaction time mean minus median AUC1.41.83.31.5-1.31.71.81.7-0.9-0.90.90.91.80.6
Reaction time num false alarms0.60.81.4-1.00.9-0.8-1.2-1.10.80.8-0.8-0.8-0.9-0.7
Reaction time num false alarms AUC0.71.02.1-1.11.0-1.0-1.4-1.30.80.8-0.8-0.8-1.2-0.6
Reaction time trials correct on left1.01.42.7-1.21.0-1.6-1.5-1.70.70.7-0.7-0.7-1.6-0.5
Reaction time trials on left0.91.32.5-1.21.0-1.6-1.4-1.60.70.7-0.7-0.7-1.6-0.5
Reaction time mean1.21.62.51.4-1.31.41.61.5-1.0-1.01.01.01.60.8
Reaction time mean AUC0.50.71.41.0-0.81.01.21.1-0.5-0.50.50.51.20.3
Median of all reaction times0.60.81.51.0-0.91.01.21.1-0.7-0.70.70.71.20.4
Reaction time omissions0.00.10.20.00.10.40.30.40.20.2-0.2-0.20.2-0.3
Reaction time false alarm rate0.10.20.3-0.50.5-0.1-0.5-0.40.50.5-0.5-0.5-0.2-0.5
Reaction time premature initiation rate1.52.03.61.3-1.50.70.60.8-1.8-1.81.81.80.41.9
Reaction time premature initiations0.81.12.70.6-1.0-0.2-0.1-0.0-1.4-1.41.41.4-0.41.7
Std. dev. reaction times0.81.11.61.2-1.11.31.21.2-0.9-0.90.90.91.20.7
Reaction time trials completed0.91.32.5-1.21.0-1.6-1.4-1.60.70.7-0.7-0.7-1.6-0.5
Reaction time trials AUC1.01.53.1-1.31.0-1.8-1.5-1.80.70.7-0.7-0.7-1.7-0.5
Run reversals in cocaine runway, females2.01.92.51.5-1.41.41.51.5-1.3-1.31.31.31.61.1
Run reversals in cocaine runway, males2.52.44.01.7-1.51.61.92.0-1.3-1.31.31.31.71.1
Latency to leave start box in cocaine runway0.40.41.1-0.30.40.40.20.20.80.8-0.8-0.80.5-1.0
Latency to leave start box in cocaine runway, F0.60.71.8-0.30.50.40.40.41.01.0-1.0-1.00.7-1.4
Latency to leave start box in cocaine runway, M0.10.10.3-0.20.1-0.2-0.4-0.5-0.1-0.10.10.1-0.60.3
Std. dev. time between licks in bursts0.70.82.00.8-0.61.31.41.4-0.3-0.30.30.31.30.0
Total sessions with >9 infusions0.91.02.1-0.60.90.90.20.81.31.3-1.3-1.30.2-1.4
Short access day 1 total inactive lever presses0.10.10.1-0.10.20.30.20.40.30.3-0.3-0.30.0-0.3
Short access day 10 total inactive lever presses0.00.00.2-0.10.10.0-0.2-0.0-0.1-0.10.10.1-0.40.3
Short access day 1 total infusions1.71.83.7-1.11.40.5-0.10.41.81.8-1.8-1.8-0.2-1.9
Short access day 10 total infusions0.91.01.4-1.11.1-0.2-0.6-0.31.21.2-1.2-1.2-0.8-1.2
Short access total infusions2.22.54.5-1.51.7-0.2-0.7-0.22.02.0-2.0-2.0-0.9-2.1
Short access day 1 locomotion0.20.31.10.1-0.01.00.61.00.20.2-0.2-0.20.5-0.3
Short access day 10 total locomotion1.61.82.31.3-1.31.50.91.5-1.4-1.41.41.41.01.5
Short access total locomotion0.20.21.00.3-0.31.00.31.0-0.2-0.20.20.20.40.1
One hour access (0.3 mA shock)0.40.50.6-0.70.8-0.5-0.6-0.60.80.8-0.8-0.8-0.7-0.7
Compulsive drug intake0.20.20.4-0.50.5-0.6-0.4-0.50.50.5-0.5-0.5-0.4-0.5
One hour access (shock baseline)0.10.10.3-0.40.4-0.1-0.4-0.20.20.2-0.2-0.2-0.6-0.1
Social response proportion0.91.01.31.0-1.10.81.10.9-1.0-1.01.01.01.00.8
Social responses8.911.512.83.6-3.63.53.53.5-3.3-3.33.33.33.42.9
Social time1.11.52.2-1.31.3-1.5-1.1-1.41.11.1-1.1-1.1-1.2-1.0
Soleus weight6.418.721.5-4.64.5-4.3-4.3-4.44.34.3-4.3-4.3-4.0-4.1
Bone: stiffness4.67.39.5-2.93.0-2.0-2.1-2.13.13.1-3.1-3.1-1.8-3.1
Tibialis anterior weight1.34.35.2-2.32.2-2.0-2.1-2.22.12.1-2.1-2.1-1.9-2.0
Time to tail flick, vehicle, before self-admin1.92.04.61.4-1.02.12.02.1-0.6-0.60.60.62.10.2
Time to tail flick, vehicle, after self-admin0.40.40.90.5-0.6-0.00.3-0.1-0.8-0.80.80.80.10.9
Time to tail flick, test, before self-admin1.11.12.81.1-0.81.41.71.4-0.5-0.50.50.51.70.2
Time to tail flick, test, after self-admin0.20.20.60.3-0.10.70.70.70.10.1-0.1-0.10.8-0.3
Delta time to tail flick, vehicle, before/after SA1.41.44.2-1.00.7-2.0-1.6-2.00.20.2-0.2-0.2-1.80.1
Delta time to tail flick, test, before/after SA0.20.20.50.2-0.4-0.3-0.3-0.3-0.6-0.60.60.6-0.40.7
Tibia length1.13.14.11.8-1.91.31.41.2-2.0-2.02.02.01.22.0
Ambulatory time before self-admin0.30.30.30.6-0.60.50.40.4-0.5-0.50.50.50.40.5
Ambulatory time after self-admin0.00.00.20.1-0.10.40.10.4-0.1-0.10.10.10.10.0
Bone: tissue strength4.44.35.3-2.22.3-1.6-1.8-1.62.32.3-2.3-2.3-1.5-2.3
Total heroin consumption2.32.73.31.8-1.81.61.71.6-1.7-1.71.71.71.61.5
Bone: trabecular number0.71.12.61.0-0.91.61.51.4-0.5-0.50.50.51.60.1
Bone: trabecular spacing0.60.82.6-0.50.3-1.4-1.4-1.3-0.3-0.30.30.3-1.60.7
Bone: trabecular thickness1.41.73.6-0.10.51.31.31.31.31.3-1.3-1.31.6-1.9
Bone: trabecular tissue density5.98.39.6-3.13.0-2.9-3.1-2.92.72.7-2.7-2.7-3.1-2.4
Water consumed over 24 hours0.91.02.1-1.01.1-0.3-0.5-0.31.31.3-1.3-1.3-0.2-1.4
Number of responses in last shaping day0.91.02.40.9-0.81.51.11.5-0.7-0.70.70.70.80.7