Hub : Genes

Itga7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 LHb gene expression Itga7 0.29 0.15 8.3e-05 0.15 0.16 0.16 0.16 2.3e-04 1.0e-04 9.8e-05 1.2e-04
2 pVTA mRNA stability Itga7 0.04 0.03 3.1e-03 0.02 0.02 0.02 0.02 1.1e-02 1.7e-02 8.9e-03 9.6e-03
3 Adipose isoform ratio XM_063264290.1 0.12 0.08 6.3e-09 0.07 0.07 0.06 0.06 7.4e-08 6.2e-08 1.5e-07 9.7e-08
4 pVTA gene expression Itga7 0.16 0.09 8.6e-11 0.14 0.12 0.13 0.12 3.1e-11 3.5e-10 2.7e-10 3.7e-10
5 NAcc gene expression Itga7 0.17 0.08 0.0e+00 0.19 0.18 0.19 0.19 2.5e-28 3.2e-27 1.8e-27 1.6e-27
6 Brain gene expression Itga7 0.2 0.12 1.8e-14 0.14 0.13 0.14 0.14 1.1e-12 9.3e-12 9.8e-13 9.8e-13
7 Adipose intron excision ratio chr7_1951997_1952890 0.06 0.04 2.7e-05 0.05 0.04 0.04 0.04 7.2e-06 1.9e-05 1.8e-05 1.1e-05
8 Adipose intron excision ratio chr7_1952638_1953879 0.05 0.03 3.8e-04 0.02 0.02 0.02 0.02 1.0e-03 1.8e-03 1.2e-03 3.1e-03
9 Adipose intron excision ratio chr7_1953009_1953879 0.05 0.03 4.1e-04 0.02 0.02 0.02 0.02 1.0e-03 1.9e-03 1.4e-03 3.4e-03
10 Liver mRNA stability Itga7 0.04 0.03 5.4e-04 0.02 0.02 0.02 0.02 1.3e-03 1.7e-03 3.5e-03 2.5e-03
11 Adipose isoform ratio NM_030842.1 0.08 0.05 2.2e-06 0.05 0.05 0.04 0.05 3.1e-06 7.0e-06 1.3e-05 6.7e-06
12 Adipose intron excision ratio chr7_1951997_1952507 0.06 0.04 3.9e-05 0.04 0.04 0.04 0.04 9.3e-06 2.6e-05 2.3e-05 1.4e-05
13 Adipose gene expression Itga7 0.25 0.14 0.0e+00 0.14 0.14 0.13 0.14 9.4e-16 6.4e-15 1.2e-14 1.7e-15
14 BLA gene expression Itga7 0.13 0.08 3.9e-07 0.12 0.12 0.11 0.12 4.9e-07 1.0e-06 2.9e-06 3.9e-07
15 NAcc mRNA stability Itga7 0.02 0.02 9.8e-03 0 0.01 0.01 0.01 2.0e-01 1.1e-02 1.4e-02 3.0e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density0.51.05.7-0.00.10.60.60.5-0.80.9-0.90.90.90.9-0.90.9-0.82.4
Area under the delay curve0.00.10.3-0.4-0.10.50.0-0.30.10.1-0.10.10.10.1-0.10.10.30.3
BMI with tail7.726.932.3-5.7-5.65.6-5.4-5.45.25.2-5.25.25.25.2-5.25.35.21.9
BMI without tail1.26.48.2-2.9-2.72.7-2.6-2.82.62.5-2.52.52.52.5-2.52.52.70.8
Body weight1.15.07.9-2.7-2.62.4-2.6-2.82.51.9-1.91.91.91.9-1.91.92.80.2
Weight adjusted by age0.00.10.20.20.1-0.30.0-0.3-0.2-0.30.3-0.3-0.3-0.30.3-0.40.1-0.4
Bone surface1.01.910.80.80.80.11.61.6-1.80.8-0.80.80.80.8-0.80.8-2.03.3
Bone volume1.02.011.80.50.50.41.31.4-1.61.1-1.11.11.11.1-1.11.1-1.83.4
Breakpoint value in progressive ratio session0.61.11.61.21.2-1.31.10.9-0.9-1.11.1-1.1-1.1-1.11.1-1.1-0.9-0.7
Number of licking bursts1.03.15.2-2.1-1.91.9-2.0-2.02.11.6-1.61.61.61.6-1.61.52.3-0.2
Context. condit. distance diff. score0.20.30.3-0.6-0.50.6-0.5-0.50.50.6-0.60.60.60.6-0.60.60.40.1
Locomotion velocity, session 10.30.42.5-0.3-0.20.80.20.3-0.40.5-0.50.50.50.5-0.50.5-0.31.6
Locomotion distance, session 10.40.52.40.60.6-0.01.01.1-1.10.1-0.10.10.10.1-0.10.1-1.21.5
Locomotion velocity, session 21.31.64.01.51.5-0.91.81.9-1.9-0.60.6-0.6-0.6-0.60.6-0.6-2.01.4
Locomotion distance, session 22.43.36.41.92.2-1.42.52.3-2.5-1.51.5-1.5-1.5-1.51.5-1.5-2.31.0
Locomotion velocity, session 34.75.46.22.42.4-2.42.32.2-2.2-2.52.5-2.5-2.5-2.52.5-2.5-2.1-1.0
Locomotion distance, session 30.10.10.20.20.3-0.30.20.2-0.2-0.40.4-0.4-0.4-0.40.4-0.4-0.1-0.4
Stereotopy head waving bouts, day 35.36.38.02.82.8-2.72.72.7-2.7-2.52.5-2.5-2.5-2.52.5-2.5-2.7-0.5
Stereotopy head waving duration, day 33.54.46.62.62.3-2.42.22.4-2.2-1.91.9-1.9-1.9-1.91.9-1.9-2.4-0.4
Locomotion velocity, session 70.10.10.30.30.3-0.10.40.5-0.4-0.00.0-0.0-0.0-0.00.0-0.0-0.60.5
Locomotion distance, session 70.10.10.6-0.4-0.30.1-0.5-0.50.60.1-0.10.10.10.1-0.10.10.5-0.7
Stereotopy head waving bouts, day 70.81.02.21.01.0-0.61.31.3-1.5-0.70.7-0.7-0.7-0.70.7-0.7-1.40.9
Stereotopy head waving duration, day 70.70.92.30.91.0-0.51.31.3-1.5-0.60.6-0.6-0.6-0.60.6-0.6-1.41.2
Locomotion velocity, session 81.21.53.51.11.5-0.61.81.6-1.9-0.80.8-0.8-0.8-0.80.8-0.8-1.71.3
Locomotion distance, session 80.30.51.10.60.9-0.51.10.7-0.9-0.60.6-0.6-0.6-0.60.6-0.6-0.80.2
Degree of sensitization distance0.60.60.8-0.8-0.80.9-0.7-0.70.70.9-0.90.90.90.9-0.90.90.60.4
Degree of sensitization stereotypy0.20.21.1-0.3-0.20.60.0-0.0-0.20.4-0.40.40.40.4-0.40.4-0.11.1
Conditioned locomotion0.81.02.3-1.2-1.20.8-1.5-1.51.40.4-0.40.40.40.4-0.40.41.5-1.0
Cocaine response after cond. corrected1.42.24.0-1.7-1.61.3-1.8-1.92.01.2-1.21.21.21.2-1.21.22.0-0.7
Cocaine response after cond. not corrected1.62.34.4-1.7-1.81.3-2.0-2.02.11.2-1.21.21.21.2-1.21.22.1-0.8
Cocaine response before conditioning0.40.50.70.90.6-0.80.50.8-0.8-0.70.7-0.7-0.7-0.70.7-0.7-0.8-0.1
Saline control response0.50.71.7-1.1-1.10.8-1.2-1.31.10.5-0.50.50.50.5-0.50.51.3-0.4
Bone: connectivity density0.30.52.80.10.10.30.50.4-0.60.6-0.60.60.60.6-0.60.6-0.61.7
Bone: cortical apparent density1.11.72.2-1.2-1.21.3-1.1-1.11.21.5-1.51.51.51.5-1.51.50.90.6
Bone: cortical area1.11.84.5-0.7-0.81.2-0.4-0.10.21.7-1.71.71.71.7-1.71.7-0.22.1
Bone: cortical porosity0.10.20.60.10.10.10.20.2-0.20.5-0.50.50.50.5-0.50.5-0.40.8
Bone: cortical porosity0.50.51.7-0.1-0.20.40.10.1-0.10.9-0.90.90.90.9-0.90.9-0.31.3
Bone: cortical thickness1.83.04.5-1.3-1.51.6-1.2-0.91.12.1-2.12.12.12.1-2.12.10.61.7
Bone: cortical thickness0.70.81.4-1.0-1.10.9-1.2-0.91.10.8-0.80.80.80.8-0.80.81.0-0.2
Bone: cortical tissue density0.71.21.6-1.0-1.01.0-0.9-0.91.01.3-1.31.31.31.3-1.31.30.70.5
Condit. Reinf. active minus inactive responses1.92.13.01.71.7-1.61.71.7-1.5-1.41.4-1.4-1.4-1.41.4-1.4-1.6-0.4
Condit. Reinf. active-inactive response ratio0.30.30.60.70.5-0.80.30.4-0.3-0.60.6-0.6-0.6-0.60.6-0.6-0.4-0.7
Condit. Reinf. active responses2.63.35.42.12.2-1.82.32.3-2.2-1.51.5-1.5-1.5-1.51.5-1.5-2.20.1
Condit. Reinf. inactive responses1.31.73.31.41.6-1.01.81.8-1.8-1.01.0-1.0-1.0-1.01.0-1.0-1.80.7
Incentive salience index mean1.21.52.91.41.6-1.11.71.7-1.6-0.90.9-0.9-0.9-0.90.9-1.0-1.60.3
Condit. Reinf. lever presses0.40.62.10.50.9-0.01.31.2-1.3-0.20.2-0.2-0.2-0.20.2-0.2-1.21.4
Condit. Reinf. active minus inactive responses2.13.24.41.81.6-2.11.21.4-1.2-2.02.0-2.0-2.0-2.02.0-2.0-1.2-1.7
Condit. Reinf. active-inactive response ratio0.81.34.10.70.6-1.20.20.2-0.1-1.41.4-1.4-1.4-1.41.4-1.4-0.0-2.0
Condit. Reinf. active responses1.62.33.51.81.5-1.91.31.6-1.3-1.61.6-1.6-1.6-1.61.6-1.6-1.5-0.7
Condit. Reinf. inactive responses0.30.40.90.80.7-0.70.81.0-0.8-0.40.4-0.4-0.4-0.40.4-0.4-1.00.5
Condit. Reinf. lever presses2.53.65.02.01.8-2.21.51.6-1.4-2.12.1-2.1-2.1-2.12.1-2.1-1.5-1.4
Condit. Reinf. lever reinforcers received1.31.82.81.51.3-1.71.01.3-1.0-1.51.5-1.5-1.5-1.51.5-1.5-1.1-1.0
Conditioned reinforcement - actives0.00.10.20.4-0.1-0.4-0.00.00.20.2-0.20.20.20.2-0.20.2-0.40.0
Conditioned reinforcement - inactives0.20.41.0-0.2-0.7-0.1-0.9-0.91.00.6-0.60.60.60.6-0.60.60.4-0.6
Conditioned locomotion1.72.56.12.31.7-2.21.71.9-1.6-1.21.2-1.2-1.2-1.21.2-1.2-2.5-0.0
Patch foraging indifference point 0 sec2.36.38.1-2.4-2.42.5-2.2-2.22.22.8-2.82.82.82.8-2.82.81.91.5
Patch foraging indifference point AUC0.41.01.41.01.1-1.01.00.8-0.9-1.11.1-1.1-1.1-1.11.1-1.2-0.7-0.7
Delay disc. indifference point, 0s delay1.92.24.9-1.5-0.91.9-0.4-0.80.51.7-1.71.71.71.7-1.71.70.62.2
Delay disc. indifference point, 16s delay0.10.20.30.40.4-0.20.40.6-0.5-0.40.4-0.4-0.4-0.40.4-0.4-0.50.1
Delay disc. indifference point, 2s delay0.40.40.9-0.7-0.20.90.0-0.30.20.7-0.70.70.70.7-0.70.70.40.9
Delay disc. indifference point, 24s delay0.20.30.8-0.9-0.50.9-0.4-0.80.50.4-0.40.40.40.4-0.40.40.70.3
Delay disc. indifference point, 4s delay0.30.30.90.40.7-0.10.90.7-0.8-0.20.2-0.2-0.2-0.20.2-0.2-0.70.8
Delay disc. indifference point, 8s delay0.10.20.7-0.7-0.40.4-0.5-0.80.60.1-0.10.10.10.1-0.10.10.9-0.5
Indifference point function ln k0.00.10.2-0.1-0.40.1-0.5-0.00.40.4-0.40.40.40.4-0.40.50.10.0
Indifference point function log k0.00.10.2-0.1-0.40.1-0.5-0.00.40.4-0.40.40.40.4-0.40.50.10.0
Patch foraging total patch changes 0 sec1.95.67.2-2.2-2.32.3-2.1-2.02.12.7-2.72.72.72.7-2.72.71.81.4
Patch foraging total patch changes 12 sec1.82.43.6-1.7-1.61.5-1.7-1.91.81.5-1.51.51.51.5-1.51.41.80.1
Patch foraging total patch changes 18 sec0.00.10.2-0.3-0.10.3-0.1-0.50.10.2-0.20.20.20.2-0.20.10.20.3
Patch foraging total patch changes 24 sec0.20.71.0-0.9-0.71.0-0.5-0.80.50.9-0.90.90.90.9-0.90.90.60.8
Patch foraging total patch changes 6 sec1.72.93.8-1.5-1.71.7-1.5-1.31.51.9-1.91.91.91.9-1.91.91.21.2
Patch foraging time to switch 0 sec0.10.51.5-0.7-0.60.8-0.4-0.40.20.8-0.80.80.80.8-0.80.80.21.2
Patch foraging water rate 0 sec0.20.71.6-0.9-0.80.6-1.0-1.11.30.6-0.60.60.60.6-0.60.61.3-0.8
Patch foraging water rate 12 sec0.20.92.0-1.0-1.20.7-1.3-1.11.40.7-0.70.70.70.7-0.70.81.3-0.7
Patch foraging water rate 18 sec0.40.85.5-0.2-0.3-0.5-0.8-0.81.0-0.60.6-0.6-0.6-0.60.6-0.61.2-2.3
Patch foraging water rate 24 sec1.62.26.6-1.6-1.60.8-2.1-2.12.30.5-0.50.50.50.5-0.50.52.6-2.2
Patch foraging water rate 6 sec0.61.04.30.80.6-1.30.10.20.1-1.01.0-1.0-1.0-1.01.0-1.1-0.0-2.1
Seeking ratio, delayed vs. immediate footshock1.01.53.11.61.4-1.41.51.6-1.4-0.90.9-0.9-0.9-0.90.9-1.0-1.80.2
Distance traveled before self-admin0.81.72.01.41.4-1.31.41.4-1.4-1.31.3-1.3-1.3-1.31.3-1.3-1.2-0.5
Distance traveled after self-admin0.00.00.0-0.1-0.00.1-0.0-0.2-0.0-0.20.2-0.2-0.2-0.20.2-0.20.2-0.1
Extensor digitorum longus weight4.819.124.5-5.0-4.94.4-4.9-4.94.94.2-4.24.24.24.2-4.24.24.90.4
Bone: elastic displacement0.00.00.0-0.0-0.10.1-0.0-0.10.10.1-0.10.10.10.1-0.10.1-0.00.1
Bone: elastic work1.01.31.7-1.1-1.01.2-0.7-0.80.71.3-1.31.31.31.3-1.31.30.71.1
Bone: endosteal estimation0.51.21.9-0.8-0.81.0-0.6-0.50.61.4-1.41.41.41.4-1.41.40.31.2
Bone: endosteal perimeter0.30.71.81.01.0-0.71.21.2-1.2-0.30.3-0.3-0.3-0.30.3-0.3-1.30.9
Epididymis fat weight0.10.51.70.20.2-0.5-0.0-0.20.1-0.80.8-0.8-0.8-0.80.8-0.80.2-1.3
Delta time in closed arm before/after self-admin1.41.33.8-1.1-1.30.5-1.7-1.61.90.6-0.60.60.60.6-0.60.61.8-1.5
Delta time in open arm before/after self-admin0.70.81.6-1.3-1.11.3-1.0-1.20.80.7-0.70.70.70.7-0.70.71.20.3
Diff in mean of infusions in LGA sessions1.32.43.11.71.6-1.81.51.5-1.4-1.61.6-1.6-1.6-1.61.6-1.6-1.4-0.8
Delay discount exponential model param0.00.00.10.3-0.0-0.4-0.10.20.00.0-0.00.00.00.0-0.00.0-0.2-0.2
Extinction: sum of active levers before priming1.32.02.71.31.3-1.61.00.9-0.8-1.61.6-1.6-1.6-1.61.6-1.6-0.7-1.4
Active lever presses in extinction session 60.20.20.50.50.6-0.40.70.5-0.6-0.30.3-0.3-0.3-0.30.3-0.3-0.60.2
Bone: final force3.15.07.0-1.9-2.12.4-1.5-1.31.22.6-2.62.62.62.6-2.62.70.92.5
Bone: final moment3.04.96.9-1.9-2.02.3-1.5-1.31.22.6-2.62.62.62.6-2.62.60.92.5
Food consumed during 24 hour testing period0.20.50.6-0.7-0.70.8-0.7-0.60.60.7-0.70.70.70.7-0.70.60.60.3
Glucose1.42.23.3-1.8-1.61.7-1.5-1.81.51.4-1.41.41.41.4-1.41.41.60.4
Heart weight0.30.50.90.60.6-0.80.30.2-0.2-0.80.8-0.8-0.8-0.80.8-0.8-0.3-1.0
Delay discount hyperbolic model param0.10.20.50.60.2-0.70.00.3-0.1-0.40.4-0.4-0.4-0.40.4-0.4-0.4-0.5
Intermittent access intake day 1-15 change0.10.71.91.10.7-1.40.40.4-0.2-0.90.9-0.9-0.9-0.90.9-0.9-0.6-1.2
Intermittent access intake escalation0.10.71.71.00.6-1.30.30.3-0.1-0.80.8-0.8-0.8-0.80.8-0.8-0.5-1.2
Intermittent access intake escalation 20.50.81.61.10.9-1.30.60.6-0.5-1.01.0-1.0-1.0-1.01.0-1.0-0.7-1.0
Intermitt. access day 1 inactive lever presses0.11.03.30.60.5-1.1-0.0-0.00.1-1.21.2-1.2-1.2-1.21.2-1.20.2-1.8
Intermitt. access day 15 inactive lever presses0.21.21.61.01.1-1.20.90.9-0.8-1.21.2-1.2-1.2-1.21.2-1.2-0.6-0.9
Intermitt. access escalation Index0.10.31.4-0.1-0.10.40.10.1-0.20.6-0.60.60.60.6-0.60.6-0.41.2
Intermittent access day 1 total infusions0.10.20.4-0.3-0.50.2-0.6-0.50.70.5-0.50.50.50.5-0.50.50.20.1
Intermittent access day 15 total infusions0.00.10.20.4-0.0-0.5-0.10.10.20.2-0.20.20.20.2-0.20.2-0.50.1
Intermittent access terminal intake (last 3 days)0.10.10.70.60.2-0.50.30.5-0.20.2-0.20.20.20.2-0.20.2-0.80.5
Intermittent access total infusions0.20.20.3-0.0-0.3-0.0-0.2-0.20.40.6-0.60.60.60.6-0.60.6-0.20.4
Intermittent access day 1 locomotion0.10.10.4-0.2-0.3-0.1-0.6-0.60.7-0.10.1-0.1-0.1-0.10.1-0.10.4-0.6
Intermittent access day 15 total locomotion0.10.31.30.90.4-1.20.10.10.0-0.50.5-0.5-0.5-0.50.5-0.5-0.6-0.9
Intermittent access total locomotion0.10.20.50.50.3-0.70.2-0.10.0-0.40.4-0.4-0.4-0.40.4-0.4-0.4-0.5
Intermittent access standard deviation0.20.92.71.51.0-1.40.91.3-1.0-0.60.6-0.6-0.6-0.60.6-0.6-1.60.1
Left kidney weight0.00.00.1-0.2-0.10.1-0.1-0.20.2-0.20.2-0.2-0.2-0.20.2-0.20.4-0.4
Right kidney weight0.10.81.30.60.7-0.70.50.4-0.5-1.11.1-1.1-1.1-1.11.1-1.1-0.3-0.8
Cocaine induced anxiety0.61.73.41.51.6-1.11.81.7-1.8-0.90.9-0.9-0.9-0.90.9-0.9-1.80.7
Post-drug Anxiety0.80.93.01.01.2-0.51.61.2-1.5-0.20.2-0.2-0.2-0.20.2-0.2-1.71.4
Baseline Anxiety0.00.00.0-0.1-0.10.1-0.1-0.10.10.2-0.20.20.20.2-0.20.20.10.0
Tail length2.513.316.03.83.8-4.03.43.3-3.3-3.93.9-3.9-3.9-3.93.9-4.0-3.0-2.0
Length with tail1.46.48.52.52.3-2.81.91.9-2.0-2.92.9-2.9-2.9-2.92.9-2.9-1.7-1.9
Length without tail0.10.71.5-0.9-1.10.8-1.2-1.11.00.6-0.60.60.60.6-0.60.61.2-0.2
Times rat made contact with spout1.11.22.3-1.3-1.31.1-1.3-1.41.30.9-0.90.90.90.9-0.90.91.5-0.2
Lifetime Intake0.70.91.5-0.4-0.80.4-0.7-0.60.81.2-1.21.21.21.2-1.21.20.00.7
Liver weight, left0.40.60.9-0.9-0.90.9-0.8-0.80.80.7-0.70.70.70.7-0.70.70.90.2
Liver weight, right0.20.30.50.10.3-0.30.1-0.2-0.1-0.70.7-0.7-0.7-0.70.7-0.70.2-0.6
Locomotor activity2.84.46.52.32.2-2.02.32.3-2.6-2.02.0-2.0-2.0-2.02.0-2.0-2.40.0
Locomotor testing distance0.92.23.51.71.6-1.51.71.7-1.9-1.31.3-1.3-1.3-1.31.3-1.3-1.90.2
Locomotor testing rearing0.00.10.2-0.0-0.1-0.1-0.2-0.30.1-0.30.3-0.3-0.3-0.30.3-0.30.2-0.4
Locomotion in novel chamber0.10.10.3-0.1-0.30.1-0.3-0.10.30.4-0.40.40.40.4-0.40.5-0.00.2
Locomotion in novel chamber post-restriction1.95.76.52.52.6-2.42.42.5-2.3-2.52.5-2.5-2.5-2.52.5-2.4-2.2-1.1
Fecal boli incidents, locomotor time 10.30.82.1-1.2-1.20.9-1.3-1.21.20.5-0.50.50.50.5-0.50.51.5-0.5
Change in fecal boli incidents, locomotor task0.60.71.80.90.9-0.51.21.2-1.2-0.30.3-0.3-0.3-0.30.3-0.3-1.31.0
Time >=10cm from walls, locomotor time 10.60.82.3-0.6-0.61.0-0.3-0.30.21.0-1.01.01.01.0-1.01.00.11.5
Bouts of movement, locomotor time 10.60.71.11.00.8-1.00.70.8-0.8-0.90.9-0.9-0.9-0.90.9-0.9-0.7-0.6
Total resting periods, locomotor time 11.31.51.91.31.3-1.41.21.2-1.2-1.31.3-1.3-1.3-1.31.3-1.3-1.1-0.6
Rest time, locomotor task time 10.30.61.00.80.8-0.60.90.8-1.0-0.70.7-0.7-0.7-0.70.7-0.7-0.80.2
Distance moved, locomotor task time 10.41.12.6-0.7-0.71.1-0.4-0.40.31.3-1.31.31.31.3-1.31.30.01.6
Vertical activity count, locomotor time 10.21.41.7-1.0-1.21.0-1.2-1.11.31.3-1.31.31.31.3-1.31.30.80.4
Time >=10cm from walls, locomotor time 20.41.11.8-1.1-1.20.9-1.3-1.31.31.0-1.01.01.01.0-1.01.01.2-0.2
Bouts of movement, locomotor time 20.10.31.00.50.4-0.20.60.9-0.8-0.10.1-0.1-0.1-0.10.1-0.1-0.81.0
Total resting periods, locomotor time 20.10.31.40.50.4-0.20.60.9-0.90.0-0.00.00.00.0-0.00.0-0.91.2
Rest time, locomotor task time 20.10.10.60.30.2-0.00.50.4-0.6-0.00.0-0.0-0.0-0.00.0-0.0-0.60.8
Distance moved, locomotor task time 20.10.10.5-0.1-0.2-0.1-0.4-0.50.5-0.10.1-0.1-0.1-0.10.1-0.10.4-0.7
Vertical activity count, locomotor time 20.51.22.5-1.2-1.20.9-1.5-1.61.60.8-0.80.80.80.8-0.80.81.5-0.7
Light reinforcement 11.35.98.32.92.6-2.82.62.6-2.6-2.32.3-2.3-2.3-2.32.3-2.3-2.8-0.6
Light reinforcement 20.61.31.91.31.2-1.41.11.2-1.2-1.11.1-1.1-1.1-1.11.1-1.1-1.2-0.4
Bone: marrow area0.41.01.7-0.7-0.80.9-0.5-0.50.51.3-1.31.31.31.3-1.31.30.31.2
Bone: maximum diameter0.50.92.81.21.1-0.71.41.5-1.4-0.20.2-0.2-0.2-0.20.2-0.2-1.71.2
Bone: maximum force2.65.17.0-2.0-2.12.4-1.6-1.51.42.6-2.62.62.62.6-2.62.71.12.3
Bone: maximum moment2.75.17.0-2.1-2.12.4-1.6-1.51.42.6-2.62.62.62.6-2.62.61.22.2
Mean time between licks in bursts0.21.11.71.31.3-1.31.11.1-0.8-1.01.0-1.0-1.0-1.01.0-1.0-1.0-0.6
Mean num. licks in bursts0.20.60.90.90.8-0.90.80.7-0.9-0.80.8-0.8-0.8-0.80.8-0.8-0.90.0
Cd content in liver0.30.40.80.80.8-0.80.90.7-0.6-0.40.4-0.4-0.4-0.40.4-0.4-0.9-0.1
Co content in liver2.73.24.21.91.8-2.01.61.5-1.5-1.91.9-1.9-1.9-1.91.9-1.9-1.4-1.3
Cu content in liver0.60.72.1-0.2-0.40.6-0.1-0.00.01.1-1.11.11.11.1-1.11.1-0.41.5
Fe content in liver0.20.20.4-0.4-0.50.3-0.6-0.50.60.4-0.40.40.40.4-0.40.40.4-0.2
K content in liver0.70.71.51.00.8-0.81.01.0-1.1-0.60.6-0.6-0.6-0.60.6-0.6-1.20.6
Mg content in liver1.11.21.81.21.2-1.11.31.3-1.3-1.01.0-1.0-1.0-1.01.0-1.0-1.20.1
Mn content in liver1.71.95.21.51.5-0.91.92.0-2.1-0.60.6-0.6-0.6-0.60.6-0.6-2.31.7
Na content in liver0.20.20.7-0.3-0.30.6-0.2-0.5-0.10.4-0.40.40.40.4-0.40.4-0.10.8
Rb content in liver0.50.62.7-0.1-0.30.50.10.2-0.10.9-0.90.90.90.9-0.90.9-0.41.6
Se content in liver0.00.00.00.10.1-0.10.20.2-0.2-0.10.1-0.1-0.1-0.10.1-0.1-0.1-0.0
Sr content in liver0.20.20.60.50.3-0.70.2-0.0-0.0-0.40.4-0.4-0.4-0.40.4-0.4-0.4-0.8
Zn content in liver3.23.75.91.81.6-2.21.11.2-1.0-2.22.2-2.2-2.2-2.22.2-2.2-0.8-2.4
Bone: minimum diameter0.40.72.1-0.2-0.20.50.10.3-0.11.1-1.11.11.11.1-1.11.0-0.41.5
Time in familiar zone, hab. session 14.44.86.12.12.2-2.31.91.8-1.9-2.52.5-2.5-2.5-2.52.5-2.5-1.6-1.5
Time in novel zone, hab. session 13.43.85.3-1.7-1.72.1-1.3-1.31.22.3-2.32.32.32.3-2.32.30.92.1
Total zone transitions, hab. session 10.40.61.70.70.9-0.31.31.1-1.3-0.30.3-0.3-0.3-0.30.3-0.3-1.11.2
Total locomotion distance, hab. session 11.62.35.11.61.9-1.02.32.0-2.3-0.90.9-0.9-0.9-0.90.9-0.9-2.21.6
Locomotion velocity, hab. session 11.72.34.91.71.9-1.22.21.9-2.2-1.11.1-1.1-1.1-1.11.1-1.1-2.11.1
Time in familiar zone, hab. session 24.95.57.22.32.3-2.71.91.9-1.7-2.62.6-2.6-2.6-2.62.6-2.6-1.7-2.0
Time in novel zone, hab. session 25.45.97.7-2.4-2.32.7-1.8-1.91.72.8-2.82.82.82.8-2.82.81.62.3
Total zone transitions, hab. session 20.91.24.9-0.6-0.51.2-0.0-0.0-0.11.3-1.31.31.31.3-1.31.3-0.32.2
Total locomotion distance, hab. session 20.30.51.20.60.8-0.21.10.9-1.1-0.30.3-0.3-0.3-0.30.3-0.3-1.01.0
Locomotion velocity, hab. session 20.50.61.70.60.9-0.21.21.0-1.3-0.30.3-0.3-0.3-0.30.3-0.3-1.21.3
Novel to familiar place preference ratio2.63.44.5-1.7-1.62.1-1.2-1.31.02.1-2.12.12.12.1-2.12.11.02.1
Novelty place preference1.82.33.5-1.3-1.21.7-0.8-1.00.81.8-1.81.81.81.8-1.81.80.71.9
Time in novel zone, NPP test2.42.94.0-1.5-1.51.9-1.1-1.21.02.0-2.02.02.02.0-2.02.00.91.9
Total zone transitions, NPP test0.40.61.7-0.8-0.61.1-0.3-0.40.10.9-0.90.90.90.9-0.90.90.41.3
Total locomotion distance, NPP test0.20.31.7-0.20.00.60.30.0-0.40.5-0.50.50.50.5-0.50.5-0.21.3
Locomotion velocity, NPP test0.10.21.20.10.30.30.60.3-0.70.1-0.10.10.10.1-0.10.1-0.41.1
Intraocular pressure0.50.83.30.10.4-0.6-0.0-0.20.1-1.01.0-1.0-1.0-1.01.0-1.00.7-1.8
Delta distance traveled before/after self-admin0.60.71.2-1.0-0.90.9-0.9-1.10.90.7-0.70.70.70.7-0.70.71.00.2
Delta ambulatory time before/after self-admin0.40.71.1-1.0-0.81.0-0.7-0.80.70.9-0.90.90.90.9-0.90.90.70.8
Parametrial fat weight0.41.01.3-0.9-1.01.0-0.9-0.90.81.1-1.11.11.11.1-1.11.10.80.8
Pavlov. Cond. lever latency0.30.41.8-0.3-0.6-0.1-1.0-0.80.8-0.20.2-0.2-0.2-0.20.2-0.20.8-1.3
Pavlov. Cond. magazine entry latency1.51.92.91.41.7-1.41.61.5-1.4-1.31.3-1.3-1.3-1.31.3-1.4-1.3-0.6
Pavlov. Cond. change in total contacts0.20.20.4-0.3-0.10.4-0.0-0.00.20.6-0.60.60.60.6-0.60.60.10.3
Pavlov. Cond. index score0.50.61.60.81.1-0.51.31.1-1.1-0.50.5-0.5-0.5-0.50.5-0.5-1.00.4
Pavlov. Cond. latency score0.60.71.90.81.2-0.51.41.3-1.2-0.40.4-0.4-0.4-0.40.4-0.4-1.20.7
Pavlov. Cond. lever contacts0.30.31.7-0.00.40.40.80.6-0.60.4-0.40.40.40.4-0.40.4-0.61.3
Pavlov. Cond. magazine entry number0.70.81.4-0.9-1.20.9-1.1-1.00.90.9-0.90.90.90.9-0.90.90.70.6
Pavlov. Cond. intertrial magazine entries0.10.21.00.20.0-0.4-0.2-0.20.3-0.40.4-0.4-0.4-0.40.4-0.40.2-1.0
Pavlov. Cond. lever-magazine prob. diff.0.50.71.70.81.2-0.61.31.2-1.1-0.60.6-0.6-0.6-0.60.6-0.6-1.10.3
Pavlov. Cond. response bias0.50.71.20.71.1-0.71.10.9-0.9-0.80.8-0.8-0.8-0.80.8-0.8-0.7-0.3
Pavlov. Cond. lever latency1.52.12.5-1.5-1.51.6-1.4-1.41.41.6-1.61.61.61.6-1.61.51.20.6
Pavlov. Cond. magazine entry latency1.92.73.61.71.9-1.71.81.7-1.7-1.71.7-1.7-1.7-1.71.7-1.7-1.4-0.6
Pavlov. Cond. change in total contacts0.41.11.51.11.0-1.20.81.1-0.8-1.11.1-1.1-1.1-1.11.1-1.1-0.9-0.7
Pavlov. Cond. index score1.62.63.21.71.7-1.81.51.7-1.5-1.71.7-1.7-1.7-1.71.7-1.7-1.4-0.8
Pavlov. Cond. latency score1.72.83.31.81.8-1.81.71.8-1.7-1.71.7-1.7-1.7-1.71.7-1.7-1.5-0.6
Pavlov. Cond. lever contacts1.42.12.51.41.5-1.61.31.3-1.2-1.61.6-1.6-1.6-1.61.6-1.6-1.1-0.9
Pavlov. Cond. magazine entry number2.22.83.8-1.9-1.91.8-1.8-1.91.71.6-1.61.61.61.6-1.61.61.70.5
Pavlov. Cond. intertrial magazine entries0.61.32.5-1.3-1.41.0-1.5-1.61.41.0-1.01.01.01.0-1.01.01.4-0.1
Pavlov. Cond. lever-magazine prob. diff.1.82.83.61.91.9-1.91.71.8-1.6-1.71.7-1.7-1.7-1.71.7-1.7-1.6-0.7
Pavlov. Cond. response bias2.33.24.01.81.9-2.01.61.6-1.5-1.91.9-1.9-1.9-1.91.9-1.9-1.4-1.2
Time in closed arm before self-admin0.20.31.3-0.2-0.20.50.00.2-0.20.6-0.60.60.60.6-0.60.6-0.41.2
Time in closed arm after self-admin0.50.50.8-0.4-0.70.3-0.8-0.50.90.9-0.90.90.90.9-0.90.90.3-0.0
Time in open arm before self-admin0.00.00.20.30.1-0.40.10.20.00.1-0.10.10.10.1-0.10.1-0.2-0.1
Time in open arm after self-admin1.51.73.0-1.7-1.51.5-1.5-1.71.41.1-1.11.11.11.1-1.11.11.70.1
Bone: periosteal estimation1.02.45.0-0.9-0.91.3-0.4-0.20.42.0-2.02.02.02.0-2.01.9-0.02.2
Bone: periosteal perimeter0.30.62.60.40.30.10.70.8-0.70.6-0.60.60.60.6-0.60.6-1.01.6
Bone: post-yield work0.40.70.8-0.8-0.90.8-0.8-0.90.70.9-0.90.90.90.9-0.90.90.80.6
Progressive ratio test 1 active lever presses0.30.51.0-0.6-0.70.4-0.7-1.00.90.7-0.70.70.70.7-0.70.70.40.2
Progressive ratio test 1 breakpoint0.30.51.1-0.6-0.70.4-0.7-1.00.90.7-0.70.70.70.7-0.70.70.50.2
Progressive ratio test 1 inactive lever presses0.10.20.70.80.5-0.90.40.5-0.3-0.30.3-0.3-0.3-0.30.3-0.3-0.7-0.2
Progressive ratio test 2 active lever presses0.00.10.20.40.3-0.50.30.1-0.1-0.10.1-0.1-0.1-0.10.1-0.1-0.5-0.0
Progressive ratio test 2 breakpoint0.10.10.30.50.4-0.60.50.2-0.2-0.20.2-0.2-0.2-0.20.2-0.2-0.6-0.0
Progressive ratio test 2 inactive lever presses0.10.20.6-0.0-0.20.10.1-0.20.10.6-0.60.60.60.6-0.60.6-0.30.7
Incentive Sensitization - Responses0.20.50.60.70.7-0.80.80.6-0.6-0.80.8-0.8-0.8-0.80.8-0.8-0.5-0.4
Incentive Sensitization - Breakpoint0.30.60.80.80.9-0.80.90.8-0.8-0.80.8-0.8-0.8-0.80.8-0.8-0.7-0.3
Sum of active levers in priming session hrs 5-60.20.20.20.40.4-0.40.30.3-0.2-0.40.4-0.4-0.4-0.40.4-0.4-0.1-0.4
Progressive ratio0.51.52.3-1.2-1.41.0-1.5-1.41.51.2-1.21.21.21.2-1.21.21.2-0.0
Food seeking constrained by brief footshock1.92.33.01.21.6-1.31.51.4-1.5-1.71.7-1.7-1.7-1.71.7-1.7-0.9-0.9
Seeking ratio, punishment vs. effort1.63.54.21.72.0-1.62.01.8-1.9-2.12.1-2.1-2.1-2.12.1-2.1-1.4-0.7
Retroperitoneal fat weight1.98.513.8-3.2-3.42.7-3.6-3.73.62.6-2.62.62.62.6-2.62.53.5-0.4
Reaction time number correct0.31.12.9-1.3-1.21.0-1.5-1.31.50.7-0.70.70.70.7-0.70.71.7-0.7
Reaction time mean minus median0.21.62.31.41.4-1.21.41.5-1.3-1.21.2-1.2-1.2-1.21.2-1.3-1.3-0.3
Reaction time mean minus median AUC0.31.83.81.41.6-1.01.91.9-1.9-0.90.9-0.9-0.9-0.90.9-1.0-1.91.0
Reaction time num false alarms0.50.91.5-1.1-1.10.9-1.2-1.21.10.9-0.90.90.90.9-0.90.91.10.2
Reaction time num false alarms AUC0.41.01.9-1.1-1.20.8-1.3-1.41.30.8-0.80.80.80.8-0.80.81.3-0.1
Reaction time trials correct on left0.31.12.9-1.3-1.21.0-1.5-1.31.50.7-0.70.70.70.7-0.70.71.7-0.7
Reaction time trials on left0.31.12.6-1.3-1.21.0-1.4-1.31.40.7-0.70.70.70.7-0.70.71.6-0.6
Reaction time mean0.71.63.11.31.5-0.91.71.8-1.7-1.01.0-1.0-1.0-1.01.0-1.0-1.60.6
Reaction time mean AUC0.30.81.90.91.1-0.51.31.4-1.2-0.50.5-0.5-0.5-0.50.5-0.6-1.20.7
Median of all reaction times0.60.92.11.01.2-0.61.41.4-1.3-0.70.7-0.7-0.7-0.70.7-0.7-1.30.7
Reaction time omissions0.10.20.70.20.2-0.00.40.6-0.30.3-0.30.30.30.3-0.30.3-0.60.8
Reaction time false alarm rate0.20.30.4-0.5-0.50.5-0.4-0.60.40.5-0.50.50.50.5-0.50.50.40.5
Reaction time premature initiation rate1.32.13.21.21.0-1.50.70.5-0.8-1.81.8-1.8-1.8-1.81.8-1.7-0.6-1.5
Reaction time premature initiations0.41.33.70.50.3-1.0-0.1-0.20.0-1.41.4-1.4-1.4-1.41.4-1.40.3-1.9
Std. dev. reaction times0.31.01.91.11.2-0.91.31.4-1.3-0.80.8-0.8-0.8-0.80.8-0.8-1.30.4
Reaction time trials completed0.31.12.6-1.3-1.21.0-1.4-1.31.40.7-0.70.70.70.7-0.70.71.6-0.6
Reaction time trials AUC0.41.33.4-1.4-1.31.1-1.6-1.41.60.7-0.70.70.70.7-0.70.71.8-0.8
Run reversals in cocaine runway, females2.42.74.21.81.9-1.52.11.9-2.0-1.51.5-1.5-1.5-1.51.5-1.5-1.90.2
Run reversals in cocaine runway, males2.12.34.11.81.8-1.51.92.0-1.9-1.21.2-1.2-1.2-1.21.2-1.2-2.00.1
Latency to leave start box in cocaine runway0.30.42.6-0.3-0.10.60.30.0-0.50.6-0.60.60.60.6-0.60.4-0.31.6
Latency to leave start box in cocaine runway, F0.50.74.3-0.3-0.10.90.40.2-0.60.8-0.80.80.80.8-0.80.5-0.52.1
Latency to leave start box in cocaine runway, M0.00.00.1-0.1-0.2-0.1-0.3-0.30.3-0.10.1-0.1-0.1-0.10.1-0.10.3-0.4
Std. dev. time between licks in bursts0.50.92.21.11.2-0.81.31.4-1.2-0.50.5-0.5-0.5-0.50.5-0.5-1.50.9
Total sessions with >9 infusions0.70.81.4-0.1-0.80.1-0.7-0.40.71.2-1.21.21.21.2-1.21.2-0.30.7
Short access day 1 total inactive lever presses0.30.51.00.70.6-1.00.30.4-0.3-0.80.8-0.8-0.8-0.80.8-0.8-0.3-0.9
Short access day 10 total inactive lever presses0.10.63.00.40.1-0.9-0.4-0.10.4-0.80.8-0.8-0.8-0.80.8-0.80.4-1.7
Short access day 1 total infusions0.40.81.4-0.1-0.80.1-0.8-0.30.71.2-1.21.21.21.2-1.21.2-0.20.7
Short access day 10 total infusions0.20.30.4-0.2-0.60.1-0.6-0.30.60.6-0.60.60.60.6-0.60.60.10.3
Short access total infusions0.91.32.1-0.4-1.00.5-0.9-0.60.91.5-1.51.51.51.5-1.51.5-0.00.9
Short access day 1 locomotion0.30.51.61.10.5-1.20.20.5-0.2-0.60.6-0.6-0.6-0.60.6-0.6-0.9-0.5
Short access day 10 total locomotion0.62.65.31.91.1-2.30.60.8-0.5-1.81.8-1.8-1.8-1.81.8-1.8-1.1-1.9
Short access total locomotion0.20.41.41.00.4-1.20.20.2-0.1-0.60.6-0.6-0.6-0.60.6-0.6-0.7-0.7
One hour access (0.3 mA shock)0.10.10.3-0.3-0.40.1-0.4-0.50.50.3-0.30.30.30.3-0.30.30.4-0.4
Compulsive drug intake0.00.00.10.10.2-0.00.30.2-0.3-0.10.1-0.1-0.1-0.10.1-0.1-0.20.1
One hour access (shock baseline)0.00.00.20.30.1-0.5-0.00.00.1-0.20.2-0.2-0.2-0.20.2-0.2-0.2-0.3
Social response proportion0.81.01.60.90.9-0.71.01.0-1.3-1.11.1-1.1-1.1-1.11.1-1.1-1.10.1
Social responses8.310.913.83.53.5-3.23.53.4-3.7-3.43.4-3.4-3.4-3.43.4-3.4-3.4-0.4
Social time0.91.42.0-1.4-1.31.3-1.4-1.31.41.0-1.01.01.01.0-1.01.01.4-0.0
Soleus weight5.817.121.1-4.6-4.54.5-4.2-4.24.04.2-4.24.24.24.2-4.24.24.11.7
Bone: stiffness3.56.48.4-2.4-2.52.7-2.0-1.91.82.9-2.92.92.92.9-2.92.91.52.1
Tibialis anterior weight1.34.45.6-2.4-2.32.3-2.2-2.12.12.1-2.12.12.12.1-2.12.12.00.8
Time to tail flick, vehicle, before self-admin0.81.02.31.31.2-1.01.31.4-1.3-0.70.7-0.7-0.7-0.70.7-0.7-1.50.3
Time to tail flick, vehicle, after self-admin0.40.72.20.40.4-0.70.10.3-0.1-1.11.1-1.1-1.1-1.11.1-1.10.4-1.5
Time to tail flick, test, before self-admin0.60.71.81.01.0-0.61.21.3-1.2-0.30.3-0.3-0.3-0.30.3-0.3-1.31.0
Time to tail flick, test, after self-admin0.10.10.30.10.00.00.20.2-0.10.3-0.30.30.30.3-0.30.3-0.30.6
Delta time to tail flick, vehicle, before/after SA1.11.14.1-1.5-1.21.0-1.4-1.51.50.4-0.40.40.40.4-0.40.42.0-1.0
Delta time to tail flick, test, before/after SA0.20.31.6-0.3-0.3-0.0-0.5-0.60.6-0.30.3-0.3-0.3-0.30.3-0.30.8-1.3
Tibia length0.92.53.41.51.6-1.61.31.1-1.3-1.81.8-1.8-1.8-1.81.8-1.8-1.0-1.1
Ambulatory time before self-admin0.20.50.60.80.7-0.80.70.6-0.7-0.70.7-0.7-0.7-0.70.7-0.7-0.6-0.4
Ambulatory time after self-admin0.00.00.1-0.2-0.10.1-0.1-0.30.0-0.00.0-0.0-0.0-0.00.0-0.00.10.1
Bone: tissue strength5.45.67.0-2.3-2.42.4-2.1-2.12.02.6-2.62.62.62.6-2.62.61.71.6
Total heroin consumption2.12.43.41.61.8-1.51.81.6-1.8-1.61.6-1.6-1.6-1.61.6-1.6-1.5-0.2
Bone: trabecular number0.30.61.80.80.8-0.41.21.1-1.3-0.30.3-0.3-0.3-0.30.3-0.3-1.21.2
Bone: trabecular spacing0.60.84.7-0.5-0.6-0.1-1.2-1.21.4-0.20.2-0.2-0.2-0.20.2-0.31.3-2.2
Bone: trabecular thickness1.42.011.30.00.10.90.91.1-1.21.3-1.31.31.31.3-1.31.3-1.33.4
Bone: trabecular tissue density3.76.58.3-2.7-2.92.5-2.9-2.72.82.5-2.52.52.52.5-2.52.52.70.3
Water consumed over 24 hours0.51.01.7-0.8-0.91.1-0.6-0.60.51.2-1.21.21.21.2-1.21.20.51.3
Number of responses in last shaping day1.82.34.81.91.3-2.21.01.3-0.9-1.51.5-1.5-1.5-1.51.5-1.5-1.5-1.2