Hub : Genes

Itga1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Itga1 0.05 0.03 5.4e-04 0.06 0.04 0.05 0.06 1.0e-05 1.7e-04 5.7e-05 2.7e-05
2 Adipose gene expression Itga1 0.2 0.08 0.0e+00 0.12 0.12 0.12 0.12 2.0e-13 3.2e-13 1.2e-13 1.2e-13
3 PL gene expression Itga1 0.03 0.02 5.9e-04 0.01 0.03 0.02 0.01 6.2e-02 5.5e-04 5.8e-03 1.1e-02
4 Adipose alternative polyA XM_039101763.2 0.03 0.02 5.1e-03 0 0.01 0 0 1.1e-01 1.8e-02 1.4e-01 8.3e-02
5 Adipose alternative polyA NM_030994.2 0.03 0.02 4.0e-03 0 0.01 0 0 1.2e-01 1.7e-02 8.4e-02 9.4e-02
6 Adipose isoform ratio NM_030994.2 0.04 0.03 1.4e-04 0.03 0.03 0.03 0.04 3.5e-04 2.2e-04 1.1e-04 5.3e-05
7 Brain mRNA stability Itga1 0.03 0.02 1.4e-03 0.03 0.03 0.04 0.03 3.8e-04 1.3e-03 2.6e-04 7.6e-04
8 Brain gene expression Itga1 0.16 0.07 1.1e-13 0.17 0.16 0.17 0.16 2.4e-15 1.8e-14 2.9e-15 3.5e-15
9 NAcc gene expression Itga1 0.03 0.02 1.1e-04 0.03 0.03 0.02 0.02 4.3e-05 3.6e-05 3.4e-04 1.1e-04
10 Adipose mRNA stability Itga1 0.04 0.02 5.2e-03 0.03 0 0.01 0.01 3.2e-04 3.2e-01 3.6e-02 2.6e-02
11 Adipose isoform ratio XM_039101763.2 0.04 0.03 4.4e-03 0.01 0.01 0.01 0.01 1.1e-02 6.2e-02 2.3e-02 1.8e-02
12 BLA gene expression Itga1 0.08 0.06 2.6e-03 0.02 0.05 0.02 0.02 2.2e-02 1.7e-03 3.5e-02 2.7e-02
13 RMTg isoform ratio NM_030994.2 0.14 0.09 6.2e-03 0.06 0.06 0 0.04 9.3e-03 1.4e-02 2.6e-01 2.5e-02
14 RMTg isoform ratio XM_039101763.2 0.16 0.1 4.1e-03 0.08 0.09 0.06 0.08 4.1e-03 2.0e-03 1.2e-02 3.5e-03
15 Liver gene expression Itga1 0.17 0.06 6.6e-12 0.06 0.07 0.07 0.07 3.1e-07 2.1e-08 1.2e-08 1.4e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bone: apparent density2.95.09.82.43.01.7-3.13.12.52.42.30.7-0.3-2.90.12.6-2.10.6
Area under the delay curve1.11.33.10.2-1.00.41.2-1.2-1.3-0.7-0.90.9-1.21.81.4-1.41.7-0.0
BMI with tail1.44.710.12.83.22.3-3.03.02.22.22.11.50.1-2.21.31.7-1.31.3
BMI without tail3.711.219.94.14.54.0-3.93.94.04.24.03.0-2.4-2.92.22.5-1.10.4
Body weight1.46.011.73.43.43.0-3.13.12.72.82.62.1-1.2-1.81.91.7-0.91.2
Weight adjusted by age0.10.10.4-0.5-0.0-0.30.3-0.30.40.30.4-0.20.2-0.4-0.70.4-0.0-0.3
Bone surface2.13.87.81.52.40.9-2.82.82.21.61.6-0.01.5-2.6-0.32.5-2.31.5
Bone volume1.62.96.31.42.20.7-2.52.51.81.31.3-0.11.2-2.3-0.22.1-2.01.5
Breakpoint value in progressive ratio session0.20.20.6-0.00.50.7-0.10.10.10.40.50.8-0.7-0.10.50.10.4-0.2
Number of licking bursts0.10.21.50.10.30.30.4-0.4-0.30.30.30.5-0.6-0.10.2-0.40.7-1.2
Context. condit. distance diff. score1.01.23.10.00.1-1.1-0.90.9-0.0-0.3-0.3-1.61.3-1.7-1.71.4-1.70.1
Locomotion velocity, session 10.40.42.2-0.8-0.3-0.80.1-0.10.1-0.3-0.3-0.81.5-0.3-0.80.5-0.60.6
Locomotion distance, session 12.43.06.21.11.40.1-2.22.22.31.31.3-0.71.5-2.2-0.82.5-2.41.7
Locomotion velocity, session 20.60.71.70.40.81.1-0.30.31.21.31.31.2-0.8-0.40.70.40.3-0.6
Locomotion distance, session 21.62.24.11.21.50.4-2.02.01.81.41.4-0.21.2-1.9-0.41.9-1.81.1
Locomotion velocity, session 30.60.73.5-0.2-0.00.70.6-0.70.10.70.70.9-1.90.70.5-0.30.9-1.3
Locomotion distance, session 30.00.00.2-0.1-0.3-0.10.3-0.3-0.00.10.1-0.2-0.40.4-0.20.20.0-0.2
Stereotopy head waving bouts, day 32.93.48.01.82.12.8-1.00.91.92.32.22.7-2.6-0.02.20.10.8-0.9
Stereotopy head waving duration, day 31.72.16.71.21.42.1-0.30.31.01.51.52.2-2.60.11.6-0.41.1-1.6
Locomotion velocity, session 70.30.30.7-0.8-0.8-0.30.7-0.7-0.5-0.5-0.50.1-0.70.60.1-0.40.50.2
Locomotion distance, session 70.91.12.1-1.2-1.4-0.71.5-1.5-1.3-1.1-1.1-0.1-0.51.10.0-1.21.2-0.4
Stereotopy head waving bouts, day 70.50.51.30.71.11.2-0.50.50.50.90.91.1-0.7-0.10.9-0.00.2-0.3
Stereotopy head waving duration, day 70.60.71.60.71.31.1-0.80.80.91.21.20.9-0.9-0.70.30.6-0.3-0.7
Locomotion velocity, session 80.50.61.7-1.3-0.8-1.30.5-0.5-0.5-0.8-0.7-1.10.9-0.1-1.10.2-0.40.5
Locomotion distance, session 82.02.96.80.20.8-1.2-1.81.81.00.20.3-1.92.4-2.6-2.02.3-2.61.4
Degree of sensitization distance0.50.51.4-1.2-0.7-0.60.9-0.9-0.6-0.8-0.7-0.2-0.00.3-0.3-0.70.6-0.6
Degree of sensitization stereotypy0.10.10.50.40.70.4-0.50.50.10.50.50.20.2-0.40.00.3-0.3-0.2
Conditioned locomotion0.40.51.10.70.81.0-0.40.41.00.80.81.0-0.9-0.40.8-0.00.4-0.1
Cocaine response after cond. corrected1.11.43.31.81.21.4-1.31.31.41.21.01.1-0.2-0.31.40.5-0.21.5
Cocaine response after cond. not corrected0.30.41.90.5-0.10.5-0.00.00.0-0.1-0.20.70.10.81.2-0.50.61.4
Cocaine response before conditioning5.06.011.2-3.4-3.0-2.73.0-3.0-3.2-3.0-3.0-1.71.22.1-1.3-2.01.2-0.7
Saline control response0.20.20.4-0.5-0.20.00.5-0.5-0.4-0.3-0.50.40.20.60.5-0.40.60.5
Bone: connectivity density2.64.18.11.92.61.5-2.82.82.32.22.20.5-0.5-2.8-0.22.6-2.00.1
Bone: cortical apparent density4.05.59.5-2.8-2.9-2.52.8-2.8-3.1-3.0-3.0-1.50.92.3-1.0-2.31.4-0.5
Bone: cortical area0.30.41.30.80.50.1-0.90.90.30.30.2-0.31.1-0.7-0.20.6-0.80.6
Bone: cortical porosity1.31.42.71.51.61.0-1.51.51.31.51.50.50.3-1.30.11.2-0.9-0.1
Bone: cortical porosity0.90.91.81.31.41.0-1.31.30.91.11.10.70.6-0.90.60.7-0.50.6
Bone: cortical thickness0.60.92.0-0.8-1.0-1.20.7-0.7-1.3-1.2-1.2-1.21.40.3-1.0-0.5-0.0-0.5
Bone: cortical thickness2.32.74.6-1.8-2.0-1.52.1-2.1-2.0-2.0-2.0-0.90.41.7-0.5-1.91.3-0.5
Bone: cortical tissue density3.95.39.1-2.7-2.8-2.32.8-2.8-3.0-2.9-2.9-1.40.82.3-0.8-2.31.5-0.4
Condit. Reinf. active minus inactive responses1.11.32.5-1.6-1.2-1.41.0-1.0-1.1-1.4-1.4-1.21.60.8-0.7-0.6-0.10.6
Condit. Reinf. active-inactive response ratio1.21.32.1-1.5-1.2-1.11.4-1.4-1.4-1.4-1.4-0.70.71.2-0.3-1.20.7-0.2
Condit. Reinf. active responses1.01.33.4-1.4-1.2-1.30.9-0.9-1.0-1.4-1.5-1.01.81.0-0.4-0.6-0.01.1
Condit. Reinf. inactive responses0.50.63.9-0.0-0.4-0.6-0.20.2-0.3-0.7-0.9-0.51.70.30.10.0-0.42.0
Incentive salience index mean0.50.63.3-0.7-0.3-1.0-0.10.1-0.3-0.6-0.7-1.21.8-0.2-0.90.4-1.00.7
Condit. Reinf. lever presses0.91.33.30.70.8-0.1-1.51.50.90.60.5-0.71.7-1.2-0.61.5-1.81.2
Condit. Reinf. active minus inactive responses1.51.94.3-2.1-1.7-1.91.1-1.1-0.8-1.7-1.7-1.61.20.8-1.2-0.1-0.31.3
Condit. Reinf. active-inactive response ratio1.21.43.6-1.8-1.1-1.70.5-0.4-0.1-1.2-1.2-1.61.50.1-1.30.5-0.91.9
Condit. Reinf. active responses0.60.92.1-1.4-1.3-1.31.0-1.0-0.8-1.1-1.1-1.20.30.5-1.1-0.1-0.3-0.1
Condit. Reinf. inactive responses0.50.61.9-0.4-0.8-0.10.9-1.0-1.0-0.5-0.50.1-1.00.90.1-0.90.7-1.4
Condit. Reinf. lever presses4.76.614.8-3.8-2.9-3.82.3-2.3-2.5-3.1-2.8-3.41.90.5-3.2-0.7-0.5-0.3
Condit. Reinf. lever reinforcers received1.21.73.9-2.0-1.7-1.81.4-1.4-1.2-1.6-1.6-1.50.50.8-1.3-0.4-0.1-0.0
Conditioned reinforcement - actives0.20.30.6-0.8-0.6-0.30.8-0.8-0.5-0.5-0.40.20.10.70.3-0.80.70.2
Conditioned reinforcement - inactives0.60.83.3-1.8-1.2-1.31.0-1.0-1.0-0.9-0.9-0.80.50.3-0.7-0.50.00.3
Conditioned locomotion0.91.12.2-1.0-1.2-0.41.4-1.4-0.9-1.1-1.20.3-0.11.50.7-1.41.40.3
Patch foraging indifference point 0 sec1.12.15.6-2.0-1.3-2.30.7-0.7-1.2-1.7-1.5-2.41.2-0.2-2.20.2-1.1-0.1
Patch foraging indifference point AUC0.10.20.8-0.10.20.2-0.00.00.30.70.80.40.4-0.6-0.20.30.1-0.9
Delay disc. indifference point, 0s delay0.80.92.4-0.2-1.00.41.3-1.3-0.9-0.4-0.50.9-0.41.51.2-1.11.5-0.4
Delay disc. indifference point, 16s delay0.30.30.8-0.4-0.7-0.70.5-0.5-0.9-0.8-0.9-0.60.00.5-0.3-0.30.10.4
Delay disc. indifference point, 2s delay1.11.24.20.80.11.50.4-0.4-0.20.40.31.9-1.71.12.1-0.81.60.3
Delay disc. indifference point, 24s delay0.20.20.70.60.00.6-0.10.10.00.1-0.10.6-0.60.60.9-0.00.10.6
Delay disc. indifference point, 4s delay2.82.97.2-0.4-1.60.42.0-2.0-1.8-1.1-1.31.3-1.42.51.9-2.32.7-0.6
Delay disc. indifference point, 8s delay0.80.92.31.3-0.30.90.5-0.5-0.9-0.2-0.40.9-1.51.21.5-0.91.3-0.5
Indifference point function ln k0.51.02.2-1.1-1.1-1.01.0-1.0-0.9-1.4-1.5-0.80.91.3-0.3-0.80.20.5
Indifference point function log k0.51.02.2-1.1-1.1-1.01.0-1.0-0.9-1.4-1.5-0.80.91.3-0.3-0.80.20.5
Patch foraging total patch changes 0 sec0.81.63.9-1.8-1.2-2.00.7-0.7-1.2-1.4-1.3-2.00.7-0.2-1.90.1-0.8-0.3
Patch foraging total patch changes 12 sec0.30.41.5-0.10.2-0.4-0.30.3-0.40.20.3-0.70.3-0.9-1.00.5-0.7-1.2
Patch foraging total patch changes 18 sec0.30.41.1-0.5-0.7-0.80.6-0.6-1.1-1.0-1.1-0.70.40.2-0.5-0.30.1-0.0
Patch foraging total patch changes 24 sec0.10.20.6-0.7-0.2-0.30.3-0.3-0.1-0.00.1-0.3-0.1-0.3-0.70.4-0.2-0.8
Patch foraging total patch changes 6 sec0.20.30.8-0.50.1-0.6-0.40.4-0.0-0.2-0.1-0.7-0.1-0.7-0.90.7-0.90.3
Patch foraging time to switch 0 sec0.10.21.60.70.2-0.0-0.40.4-0.0-0.5-0.6-0.3-0.2-0.00.2-0.1-0.21.3
Patch foraging water rate 0 sec0.51.04.3-0.5-0.50.51.2-1.2-0.60.30.30.9-1.11.10.6-0.91.3-2.1
Patch foraging water rate 12 sec0.71.64.11.10.91.9-0.60.51.61.81.72.0-1.00.31.70.30.60.3
Patch foraging water rate 18 sec0.30.41.3-0.00.20.80.0-0.00.50.80.81.1-0.50.61.00.10.50.8
Patch foraging water rate 24 sec0.10.20.9-0.30.00.0-0.20.20.60.40.40.20.60.10.10.7-0.20.9
Patch foraging water rate 6 sec0.60.82.2-0.9-0.90.31.1-1.1-0.2-0.1-0.21.0-0.41.51.1-1.01.50.2
Seeking ratio, delayed vs. immediate footshock0.91.12.81.60.91.7-0.50.50.10.80.71.6-1.60.21.6-0.20.8-0.3
Distance traveled before self-admin2.02.66.60.20.6-1.1-1.41.41.50.50.6-2.02.5-1.9-2.12.1-2.61.2
Distance traveled after self-admin0.91.13.8-0.8-0.8-1.80.1-0.1-0.5-0.8-0.7-1.91.3-0.4-1.80.5-1.10.9
Extensor digitorum longus weight2.07.913.92.93.51.7-3.73.73.22.93.0-0.0-0.3-3.7-0.93.6-3.3-0.8
Bone: elastic displacement0.20.21.21.10.60.7-0.50.40.10.40.40.4-0.30.10.50.00.1-0.2
Bone: elastic work0.30.41.51.20.50.7-0.40.4-0.2-0.1-0.20.70.10.61.2-0.60.61.0
Bone: endosteal estimation1.53.28.52.92.32.2-2.32.31.61.71.51.6-0.3-0.62.00.8-0.52.2
Bone: endosteal perimeter2.34.88.93.02.92.3-2.92.92.82.32.11.5-0.3-1.61.61.7-1.21.9
Epididymis fat weight0.41.43.92.01.31.5-1.51.51.01.00.81.1-0.1-0.51.50.4-0.31.3
Delta time in closed arm before/after self-admin1.31.23.50.3-0.40.90.7-0.7-0.5-0.3-0.51.4-1.81.51.9-1.41.50.8
Delta time in open arm before/after self-admin1.21.24.3-0.3-0.1-1.4-0.30.3-0.4-0.3-0.1-1.91.8-1.0-2.10.8-1.3-1.1
Diff in mean of infusions in LGA sessions0.50.61.1-1.1-0.9-0.40.9-0.9-0.7-0.8-0.80.20.10.90.3-0.90.91.0
Delay discount exponential model param1.31.53.5-0.40.9-0.7-1.21.21.20.60.9-1.21.4-1.9-1.71.5-1.9-0.1
Extinction: sum of active levers before priming0.80.93.8-0.20.61.2-0.30.30.91.31.31.4-1.9-0.21.00.20.40.3
Active lever presses in extinction session 60.80.83.70.50.51.3-0.20.20.10.80.61.5-1.90.41.4-0.20.70.2
Bone: final force1.11.87.7-0.6-0.2-1.5-0.70.8-0.0-0.8-0.8-1.82.8-0.8-1.31.0-1.72.2
Bone: final moment1.01.67.0-0.00.1-1.1-1.01.10.2-0.5-0.5-1.52.7-0.8-1.01.1-1.72.4
Food consumed during 24 hour testing period0.60.83.0-1.0-0.8-1.30.4-0.4-0.5-1.1-1.1-1.21.7-0.0-1.00.1-0.50.7
Glucose0.00.10.40.70.30.0-0.30.3-0.10.10.1-0.10.4-0.20.1-0.0-0.10.3
Heart weight0.30.50.90.60.70.9-0.60.61.00.80.80.8-0.60.00.90.4-0.20.9
Delay discount hyperbolic model param1.51.74.1-0.30.9-0.8-1.21.21.20.60.8-1.41.5-1.9-1.91.6-2.0-0.1
Intermittent access intake day 1-15 change1.02.04.2-0.9-1.5-0.71.8-1.9-2.0-1.5-1.5-0.3-0.01.6-0.1-1.71.4-1.9
Intermittent access intake escalation0.61.33.3-0.6-1.1-0.41.5-1.5-1.6-1.0-1.0-0.1-0.21.30.0-1.31.2-1.8
Intermittent access intake escalation 21.01.23.3-0.3-1.0-0.61.4-1.4-1.6-1.1-1.1-0.50.41.1-0.2-1.20.9-1.8
Intermitt. access day 1 inactive lever presses0.20.82.0-1.2-0.6-1.40.4-0.4-0.7-0.9-0.8-1.41.4-0.3-1.40.1-0.50.2
Intermitt. access day 15 inactive lever presses0.20.41.00.70.71.0-0.40.40.40.80.70.9-1.0-0.40.70.10.1-0.9
Intermitt. access escalation Index2.12.97.11.12.11.6-1.91.92.22.52.71.1-0.4-1.70.22.0-1.10.2
Intermittent access day 1 total infusions0.40.71.7-0.8-0.50.20.9-0.9-0.2-0.4-0.40.9-0.61.11.1-1.01.30.7
Intermittent access day 15 total infusions0.91.43.3-0.3-0.90.31.5-1.5-1.1-0.8-0.80.8-0.61.71.1-1.71.8-1.2
Intermittent access terminal intake (last 3 days)0.70.92.4-0.2-0.60.41.2-1.2-0.8-0.5-0.50.8-1.01.30.9-1.31.6-1.2
Intermittent access total infusions0.70.82.50.30.01.00.6-0.6-0.10.10.01.4-1.21.11.6-1.11.6-0.2
Intermittent access day 1 locomotion0.30.41.3-0.4-0.40.10.7-0.7-0.4-0.5-0.60.4-0.21.10.7-1.01.00.7
Intermittent access day 15 total locomotion0.40.81.7-0.5-1.0-0.31.1-1.1-0.7-1.0-1.10.2-0.01.30.7-1.21.20.6
Intermittent access total locomotion1.01.22.9-0.5-1.1-0.21.2-1.2-0.9-1.2-1.30.30.21.70.9-1.51.50.9
Intermittent access standard deviation1.42.85.6-0.9-1.7-0.32.3-2.3-2.0-1.6-1.60.6-0.72.21.0-2.32.4-1.4
Left kidney weight0.52.45.60.91.91.5-1.41.42.32.22.41.0-1.5-1.5-0.01.7-0.8-1.0
Right kidney weight0.20.82.2-0.10.81.0-0.10.11.31.41.51.3-1.5-0.30.60.20.6-0.5
Cocaine induced anxiety0.20.31.3-0.7-0.0-0.5-0.00.00.50.00.2-0.51.1-0.5-0.70.5-0.5-0.0
Post-drug Anxiety0.30.31.6-0.90.1-0.7-0.10.10.2-0.2-0.1-0.71.3-0.5-0.80.5-0.70.4
Baseline Anxiety0.10.10.6-0.20.0-0.10.2-0.2-0.8-0.4-0.4-0.0-0.40.40.1-0.50.3-0.2
Tail length0.93.67.72.22.02.5-1.61.62.22.52.52.0-2.8-0.91.41.1-0.1-0.6
Length with tail0.41.63.11.81.51.3-1.61.51.71.51.40.7-1.2-0.90.51.2-0.80.2
Length without tail0.20.71.8-0.4-0.8-0.80.6-0.6-0.9-1.3-1.3-0.60.81.0-0.0-0.90.30.7
Times rat made contact with spout2.32.75.31.32.20.8-2.12.12.01.71.70.21.5-2.3-0.42.1-1.70.1
Lifetime Intake0.60.72.2-0.1-0.10.70.7-0.7-0.3-0.2-0.21.2-0.71.11.4-1.11.50.2
Liver weight, left0.91.46.00.70.61.4-0.10.10.10.30.12.1-0.40.92.4-1.11.71.8
Liver weight, right0.40.72.1-0.8-0.8-0.80.6-0.6-0.8-1.0-1.0-0.31.20.80.2-0.80.41.4
Locomotor activity2.84.39.02.92.53.0-2.12.12.12.52.32.5-1.5-0.62.40.9-0.21.0
Locomotor testing distance1.42.56.02.41.92.0-1.91.91.61.91.71.4-0.6-0.91.41.1-0.61.0
Locomotor testing rearing0.51.03.41.50.51.4-0.50.50.40.70.51.4-0.30.61.9-0.30.61.4
Locomotion in novel chamber0.10.10.8-0.4-0.1-0.10.5-0.5-0.30.10.20.2-0.30.1-0.1-0.20.4-0.9
Locomotion in novel chamber post-restriction0.20.41.1-0.9-0.6-1.00.3-0.3-0.1-0.3-0.2-1.00.6-0.2-1.10.2-0.5-0.3
Fecal boli incidents, locomotor time 11.82.74.91.81.81.4-2.22.22.21.71.60.9-0.2-1.40.81.5-1.12.2
Change in fecal boli incidents, locomotor task0.10.10.3-0.5-0.3-0.10.5-0.5-0.3-0.1-0.10.00.10.4-0.10.00.2-0.2
Time >=10cm from walls, locomotor time 10.91.01.71.21.31.1-1.21.20.91.21.20.9-0.0-0.80.90.7-0.20.8
Bouts of movement, locomotor time 10.30.31.0-0.30.70.3-0.20.20.80.81.00.5-0.6-0.6-0.10.50.1-0.7
Total resting periods, locomotor time 10.30.30.9-0.10.80.4-0.30.30.80.80.90.6-0.5-0.60.00.40.2-0.4
Rest time, locomotor task time 10.30.40.8-0.7-0.2-0.10.6-0.6-0.9-0.6-0.60.50.00.70.5-0.80.90.8
Distance moved, locomotor task time 10.50.82.6-0.20.1-0.8-0.60.60.50.40.5-1.30.4-1.2-1.51.2-1.6-0.7
Vertical activity count, locomotor time 10.30.72.0-0.20.1-0.6-0.40.40.90.60.6-1.00.4-1.2-1.41.1-1.3-0.9
Time >=10cm from walls, locomotor time 20.91.32.71.31.51.3-0.80.81.31.41.50.9-1.2-1.10.30.8-0.0-1.6
Bouts of movement, locomotor time 21.01.75.2-0.6-0.70.41.5-1.5-1.3-0.5-0.61.2-1.91.51.1-1.52.3-1.1
Total resting periods, locomotor time 21.11.95.9-0.7-0.80.31.6-1.6-1.6-0.7-0.81.2-1.81.61.1-1.62.4-1.0
Rest time, locomotor task time 21.31.64.8-1.0-1.1-0.71.1-1.1-2.2-1.6-1.70.10.51.40.6-1.61.31.4
Distance moved, locomotor task time 20.80.94.00.51.00.2-0.60.61.01.01.2-0.2-0.5-1.4-0.81.0-0.8-2.0
Vertical activity count, locomotor time 21.01.43.9-0.00.8-0.4-0.60.61.20.91.2-0.90.2-1.9-1.71.5-1.2-2.0
Light reinforcement 10.40.93.0-0.10.31.10.5-0.5-0.20.10.11.7-0.71.21.7-1.11.60.5
Light reinforcement 21.11.64.3-0.4-1.00.31.4-1.4-1.4-0.9-0.91.0-0.12.01.5-2.12.00.0
Bone: marrow area1.63.59.33.02.32.3-2.32.31.71.81.51.8-0.4-0.52.20.7-0.42.2
Bone: maximum diameter2.34.38.12.82.71.9-2.92.82.52.32.20.80.2-2.10.52.1-1.80.6
Bone: maximum force0.71.36.30.10.3-0.8-1.01.00.3-0.3-0.4-1.22.5-0.8-0.80.9-1.52.0
Bone: maximum moment0.71.25.50.60.6-0.4-1.31.30.5-0.0-0.1-0.82.4-0.8-0.41.0-1.52.1
Mean time between licks in bursts1.02.59.61.80.72.2-0.20.2-0.10.60.42.4-1.81.73.1-1.51.71.2
Mean num. licks in bursts1.01.53.50.50.8-0.2-1.51.51.30.50.5-0.81.9-1.3-0.71.7-1.91.4
Cd content in liver1.82.04.6-1.0-1.7-1.61.2-1.2-1.8-2.1-2.1-1.41.41.3-0.6-1.00.30.9
Co content in liver0.60.71.6-1.0-1.0-1.10.5-0.5-1.2-1.0-1.0-0.90.60.5-0.5-0.1-0.21.3
Cu content in liver1.11.43.5-0.0-0.50.71.0-1.0-1.0-0.3-0.41.4-1.51.71.7-1.71.90.5
Fe content in liver0.30.41.10.50.60.7-0.60.61.00.80.80.6-0.8-0.20.50.5-0.20.4
K content in liver2.32.25.3-1.6-1.4-2.21.0-1.0-1.7-1.5-1.3-2.31.7-0.2-2.30.1-0.7-0.7
Mg content in liver3.73.87.3-2.4-2.3-2.71.9-1.9-2.5-2.5-2.3-2.31.91.0-1.8-1.00.2-0.1
Mn content in liver0.60.75.40.2-0.30.20.6-0.7-0.90.20.20.2-1.50.3-0.1-0.60.7-2.3
Na content in liver0.40.51.70.4-0.0-0.7-0.20.2-0.5-0.2-0.1-1.2-0.3-0.9-1.30.6-0.7-0.9
Rb content in liver2.42.85.4-1.3-1.8-1.02.1-2.1-2.3-1.7-1.7-0.1-1.12.00.4-2.32.1-0.2
Se content in liver0.80.92.1-0.9-1.0-1.20.7-0.7-1.0-1.3-1.3-1.31.50.3-1.0-0.3-0.2-0.0
Sr content in liver0.70.61.50.80.80.7-1.01.00.71.00.90.20.8-0.40.21.2-1.10.4
Zn content in liver2.62.97.1-1.5-1.8-0.92.1-2.1-2.7-1.8-1.8-0.00.62.30.6-2.21.90.1
Bone: minimum diameter0.30.62.31.20.40.9-0.40.4-0.10.30.21.0-0.10.51.5-0.60.71.4
Time in familiar zone, hab. session 10.40.41.41.20.50.7-0.70.70.80.40.20.5-0.1-0.10.80.3-0.11.2
Time in novel zone, hab. session 11.01.03.80.50.31.20.4-0.4-0.40.70.71.4-1.90.71.0-0.81.1-1.7
Total zone transitions, hab. session 10.70.95.6-0.6-0.3-0.9-0.20.20.3-0.8-0.9-0.72.10.1-0.10.0-0.52.4
Total locomotion distance, hab. session 10.60.91.90.40.90.0-1.21.21.40.30.2-0.21.3-1.2-0.21.0-1.01.4
Locomotion velocity, hab. session 10.60.82.50.20.8-0.3-1.01.01.20.00.0-0.41.6-1.2-0.40.9-1.01.4
Time in familiar zone, hab. session 20.30.30.60.30.40.3-0.50.40.70.50.6-0.0-0.5-0.7-0.40.8-0.6-0.7
Time in novel zone, hab. session 20.50.51.2-0.3-0.6-0.30.6-0.6-0.9-0.9-1.0-0.00.61.10.5-1.00.70.9
Total zone transitions, hab. session 22.32.97.21.61.60.9-2.32.42.11.41.20.31.4-1.60.41.9-1.82.7
Total locomotion distance, hab. session 23.64.79.12.42.71.7-2.93.03.02.22.10.90.6-2.30.72.3-1.81.7
Locomotion velocity, hab. session 23.75.09.42.62.81.8-3.03.13.12.32.11.00.5-2.40.82.3-1.81.7
Novel to familiar place preference ratio0.80.92.2-0.4-0.7-0.01.1-1.1-1.1-0.5-0.50.6-1.00.90.6-1.51.5-1.2
Novelty place preference0.80.92.7-0.2-0.40.41.0-1.0-0.7-0.2-0.31.0-1.20.91.0-1.51.6-1.0
Time in novel zone, NPP test1.01.13.3-0.2-0.40.51.0-1.0-0.8-0.2-0.31.1-1.41.11.2-1.71.8-1.0
Total zone transitions, NPP test1.01.42.80.61.0-0.1-1.51.61.40.60.6-0.61.6-1.4-0.61.5-1.71.5
Total locomotion distance, NPP test1.01.32.60.90.90.1-1.61.61.40.60.5-0.51.1-1.6-0.51.5-1.61.1
Locomotion velocity, NPP test0.81.12.50.70.8-0.1-1.41.41.20.50.4-0.61.2-1.6-0.61.5-1.51.0
Intraocular pressure2.13.17.8-1.0-1.40.62.1-2.1-1.1-0.9-1.01.7-1.32.82.1-2.62.8-0.2
Delta distance traveled before/after self-admin0.70.81.8-0.7-1.1-0.31.0-1.0-1.4-0.8-0.80.2-1.01.10.4-1.01.10.1
Delta ambulatory time before/after self-admin0.50.62.0-0.8-1.1-0.60.9-0.9-1.4-0.8-0.8-0.1-0.70.9-0.1-0.80.8-0.0
Parametrial fat weight0.30.72.00.70.40.9-0.20.20.20.60.41.3-1.00.41.4-0.50.91.4
Pavlov. Cond. lever latency1.11.33.6-0.2-0.60.41.3-1.3-1.2-0.5-0.50.9-1.51.41.0-1.71.9-1.2
Pavlov. Cond. magazine entry latency0.30.41.6-0.4-0.6-0.10.5-0.5-0.3-0.4-0.60.40.10.90.7-0.60.61.3
Pavlov. Cond. change in total contacts0.30.30.9-0.4-0.20.50.4-0.4-0.00.20.10.9-0.70.70.9-0.60.70.7
Pavlov. Cond. index score0.10.10.70.10.20.1-0.40.40.40.30.20.10.3-0.30.10.4-0.40.8
Pavlov. Cond. latency score0.30.41.10.10.3-0.2-0.70.70.60.30.2-0.40.9-0.7-0.40.9-1.01.0
Pavlov. Cond. lever contacts0.60.72.10.20.3-0.4-0.90.90.70.30.4-0.81.1-1.1-0.91.3-1.40.8
Pavlov. Cond. magazine entry number0.30.41.2-0.3-0.5-0.80.3-0.3-0.6-0.5-0.4-1.00.5-0.2-1.10.1-0.4-0.9
Pavlov. Cond. intertrial magazine entries0.10.10.2-0.2-0.1-0.3-0.10.10.2-0.2-0.2-0.40.50.1-0.20.2-0.40.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.50.10.00.3-0.10.10.20.20.10.4-0.20.10.50.00.10.7
Pavlov. Cond. response bias0.10.21.1-0.10.20.2-0.30.30.60.30.30.30.1-0.10.30.3-0.21.0
Pavlov. Cond. lever latency5.06.814.83.83.13.8-2.52.52.83.12.93.3-2.0-0.93.01.00.30.3
Pavlov. Cond. magazine entry latency2.22.66.2-2.3-1.8-2.21.2-1.2-1.7-1.9-1.8-1.82.50.6-1.4-0.5-0.31.0
Pavlov. Cond. change in total contacts4.37.015.0-3.8-3.1-3.92.3-2.3-2.6-3.3-3.2-3.22.61.0-2.7-1.0-0.40.9
Pavlov. Cond. index score3.95.311.6-3.4-2.7-3.22.2-2.2-2.5-2.9-2.7-2.62.31.0-2.2-1.1-0.10.4
Pavlov. Cond. latency score3.64.810.5-3.2-2.5-3.12.0-2.0-2.3-2.7-2.5-2.72.40.7-2.3-0.8-0.30.3
Pavlov. Cond. lever contacts4.76.514.9-3.9-3.0-3.62.6-2.5-2.9-3.0-2.9-3.01.71.0-2.7-1.2-0.1-0.4
Pavlov. Cond. magazine entry number4.55.511.23.42.93.0-2.42.32.63.02.92.2-2.5-1.51.71.4-0.3-0.9
Pavlov. Cond. intertrial magazine entries0.50.82.61.50.61.3-0.40.40.70.80.71.1-1.60.31.20.00.5-0.5
Pavlov. Cond. lever-magazine prob. diff.4.15.511.5-3.4-2.7-3.22.2-2.2-2.6-3.0-2.8-2.52.41.1-2.1-1.20.10.6
Pavlov. Cond. response bias6.28.518.8-4.3-3.5-4.02.9-2.9-3.3-3.6-3.4-3.22.21.4-2.7-1.50.10.2
Time in closed arm before self-admin0.50.61.8-0.3-0.40.20.9-0.9-1.0-0.1-0.10.8-1.20.90.7-0.91.3-0.8
Time in closed arm after self-admin2.32.49.80.80.11.80.7-0.7-0.50.40.32.5-3.11.42.5-1.52.3-0.1
Time in open arm before self-admin0.00.00.3-0.20.20.2-0.10.10.50.10.00.2-0.3-0.20.10.1-0.2-0.4
Time in open arm after self-admin1.11.23.00.30.5-0.7-0.90.90.20.20.3-1.61.6-1.3-1.71.1-1.7-1.0
Bone: periosteal estimation0.91.85.32.31.71.3-1.91.91.11.00.90.80.6-0.71.20.7-0.71.7
Bone: periosteal perimeter1.22.04.32.12.11.3-2.12.11.61.31.20.60.4-1.40.61.2-1.10.7
Bone: post-yield work0.20.32.30.0-0.3-0.3-0.10.1-0.1-0.3-0.4-0.31.50.20.1-0.1-0.31.1
Progressive ratio test 1 active lever presses0.30.42.6-0.6-0.5-0.70.2-0.2-0.4-0.7-0.7-0.50.80.4-0.1-0.50.11.6
Progressive ratio test 1 breakpoint0.30.42.4-0.5-0.4-0.60.2-0.2-0.4-0.7-0.6-0.30.70.50.0-0.50.21.6
Progressive ratio test 1 inactive lever presses0.30.42.10.30.80.8-0.70.70.50.60.50.8-0.1-0.30.80.1-0.01.4
Progressive ratio test 2 active lever presses0.81.02.4-0.3-0.80.21.0-1.0-1.0-0.9-1.00.8-0.11.41.3-1.51.50.5
Progressive ratio test 2 breakpoint0.91.12.6-0.2-0.80.31.0-1.0-1.0-0.9-1.00.9-0.21.41.4-1.61.60.4
Progressive ratio test 2 inactive lever presses0.50.82.20.50.91.3-0.60.61.11.21.11.5-0.9-0.41.20.30.20.2
Incentive Sensitization - Responses0.50.72.50.80.01.10.3-0.3-0.20.20.11.4-0.70.71.6-0.81.2-0.5
Incentive Sensitization - Breakpoint0.50.72.60.8-0.01.10.4-0.4-0.30.10.01.4-0.70.81.6-0.91.2-0.6
Sum of active levers in priming session hrs 5-63.12.85.31.22.22.0-1.51.52.22.22.31.7-2.0-1.50.71.3-0.4-1.0
Progressive ratio0.91.43.21.81.61.7-1.21.21.21.51.41.2-0.4-0.71.00.7-0.2-0.5
Food seeking constrained by brief footshock1.31.63.21.51.81.4-1.61.61.21.51.51.1-0.2-1.20.71.1-0.60.2
Seeking ratio, punishment vs. effort0.20.30.9-0.9-0.7-0.90.3-0.3-0.5-0.6-0.5-0.70.40.1-0.7-0.1-0.10.2
Retroperitoneal fat weight0.93.78.72.91.72.8-1.71.71.51.91.52.5-1.50.13.00.10.52.2
Reaction time number correct0.20.51.0-0.6-1.0-0.80.8-0.8-0.6-0.7-0.7-0.50.60.9-0.3-0.40.40.5
Reaction time mean minus median0.30.81.9-0.9-1.0-0.11.1-1.1-0.6-0.9-1.00.4-0.61.40.8-1.41.00.2
Reaction time mean minus median AUC0.61.42.7-1.4-1.5-1.01.4-1.4-1.3-1.6-1.6-0.60.31.3-0.1-1.50.8-0.3
Reaction time num false alarms1.11.56.5-1.2-1.1-1.70.5-0.5-0.9-1.4-1.3-1.82.5-0.1-1.6-0.1-0.6-0.1
Reaction time num false alarms AUC1.01.56.2-1.3-1.1-1.70.6-0.5-0.8-1.3-1.2-1.72.5-0.1-1.6-0.1-0.6-0.2
Reaction time trials correct on left0.20.51.0-0.6-1.0-0.80.8-0.8-0.6-0.7-0.7-0.50.60.9-0.3-0.40.40.5
Reaction time trials on left0.30.51.0-0.6-1.0-0.70.9-0.9-0.7-0.7-0.7-0.50.51.0-0.2-0.50.40.5
Reaction time mean0.91.53.0-1.4-1.6-0.51.5-1.5-1.3-1.2-1.20.2-0.91.60.5-1.71.3-0.1
Reaction time mean AUC1.01.52.9-1.6-1.7-0.81.6-1.6-1.5-1.3-1.3-0.1-0.61.40.2-1.61.1-0.3
Median of all reaction times1.01.42.6-1.4-1.5-0.61.5-1.5-1.4-1.1-1.10.1-0.81.50.4-1.61.2-0.3
Reaction time omissions1.42.13.9-1.3-1.60.11.8-1.8-1.1-1.0-1.00.9-1.82.01.1-1.91.9-0.8
Reaction time false alarm rate0.30.51.8-0.7-0.3-0.90.1-0.1-0.4-0.7-0.6-0.91.3-0.5-1.0-0.0-0.4-0.7
Reaction time premature initiation rate0.40.62.70.20.40.2-0.40.30.60.91.0-0.2-0.3-1.1-0.91.1-0.7-1.6
Reaction time premature initiations0.30.51.90.10.1-0.2-0.20.20.40.70.8-0.60.1-0.8-1.11.1-0.7-1.4
Std. dev. reaction times0.71.32.9-1.3-1.4-0.21.4-1.4-0.9-1.1-1.20.5-0.91.60.8-1.71.20.2
Reaction time trials completed0.30.51.0-0.6-1.0-0.70.9-0.9-0.7-0.7-0.7-0.50.51.0-0.2-0.50.40.5
Reaction time trials AUC0.20.40.8-0.4-0.9-0.70.7-0.7-0.6-0.7-0.7-0.50.60.9-0.2-0.40.30.6
Run reversals in cocaine runway, females0.70.73.2-0.8-1.0-1.00.5-0.5-0.8-1.0-1.1-0.70.70.7-0.2-0.40.11.8
Run reversals in cocaine runway, males0.50.51.80.4-0.30.60.5-0.5-0.7-0.0-0.10.8-1.40.90.9-0.81.0-0.9
Latency to leave start box in cocaine runway0.60.73.01.50.51.3-0.40.40.00.30.11.20.30.71.7-0.30.71.0
Latency to leave start box in cocaine runway, F0.30.41.10.6-0.10.2-0.0-0.0-0.5-0.6-0.70.30.90.70.9-0.60.61.1
Latency to leave start box in cocaine runway, M1.21.13.51.40.81.8-0.50.50.61.11.01.8-0.80.41.90.00.60.2
Std. dev. time between licks in bursts0.81.12.7-0.6-0.9-0.21.3-1.3-1.5-0.9-0.90.3-0.31.60.6-1.61.4-0.7
Total sessions with >9 infusions0.50.61.2-1.0-0.7-0.31.1-1.1-1.0-0.7-0.60.2-0.11.10.4-1.11.1-0.1
Short access day 1 total inactive lever presses0.91.22.21.51.51.4-1.31.31.11.51.40.8-0.5-0.80.60.8-0.5-0.2
Short access day 10 total inactive lever presses0.20.41.4-0.40.2-0.7-0.20.20.1-0.2-0.2-1.00.9-0.7-1.20.6-0.8-0.4
Short access day 1 total infusions0.10.20.40.20.60.6-0.30.30.30.50.50.6-0.1-0.10.50.00.30.5
Short access day 10 total infusions1.31.63.0-1.6-1.4-0.91.7-1.7-1.3-1.5-1.4-0.20.41.60.2-1.51.5-0.2
Short access total infusions0.50.61.2-0.9-0.6-0.31.0-1.0-0.8-0.8-0.70.20.21.00.4-1.11.10.3
Short access day 1 locomotion0.60.81.9-1.0-0.8-0.21.3-1.3-0.5-0.6-0.60.5-0.41.20.5-1.21.4-0.1
Short access day 10 total locomotion2.34.37.9-1.8-2.6-2.32.3-2.4-2.5-2.8-2.8-1.91.62.1-1.0-1.90.9-0.5
Short access total locomotion1.41.62.7-1.3-1.5-1.41.6-1.6-1.5-1.6-1.6-1.01.11.4-0.5-1.30.8-0.3
One hour access (0.3 mA shock)0.91.02.40.1-0.70.51.1-1.1-0.9-0.6-0.60.9-0.81.21.1-1.41.6-1.4
Compulsive drug intake0.40.42.01.40.31.0-0.40.4-0.60.2-0.00.8-0.70.31.1-0.40.4-0.2
One hour access (shock baseline)0.20.42.5-0.3-0.30.10.8-0.80.1-0.00.00.3-0.30.40.1-0.50.8-1.6
Social response proportion0.70.83.21.30.71.3-0.40.4-0.10.60.41.2-1.80.41.5-0.70.60.0
Social responses0.10.10.6-0.8-0.1-0.50.1-0.1-0.0-0.3-0.3-0.3-0.0-0.3-0.3-0.1-0.10.8
Social time0.10.10.5-0.0-0.1-0.2-0.20.20.00.20.1-0.50.4-0.2-0.40.2-0.7-0.4
Soleus weight5.315.532.94.44.65.7-2.82.73.95.25.15.2-5.1-1.53.91.01.1-2.0
Bone: stiffness0.40.62.5-0.20.1-0.6-0.70.80.30.10.0-0.71.6-0.8-0.60.8-1.11.5
Tibialis anterior weight2.68.914.53.43.82.9-3.73.73.53.83.81.4-1.4-3.20.53.1-2.4-1.0
Time to tail flick, vehicle, before self-admin1.71.74.4-0.90.3-1.2-0.90.91.20.50.6-1.61.7-1.6-1.91.8-2.10.8
Time to tail flick, vehicle, after self-admin0.50.62.40.60.70.6-0.70.71.50.90.90.4-0.7-0.70.30.9-0.51.0
Time to tail flick, test, before self-admin0.70.71.7-0.10.60.1-0.60.61.00.91.0-0.2-0.2-1.3-0.81.2-1.0-1.3
Time to tail flick, test, after self-admin0.10.10.80.3-0.00.60.1-0.10.10.30.20.7-0.00.40.9-0.10.30.5
Delta time to tail flick, vehicle, before/after SA1.01.02.91.50.91.5-0.50.50.80.80.71.4-1.70.11.4-0.10.7-0.1
Delta time to tail flick, test, before/after SA0.60.62.11.00.61.2-0.40.40.10.50.41.1-0.20.51.5-0.20.41.5
Tibia length0.10.20.60.8-0.00.60.2-0.2-0.10.30.30.6-0.70.70.7-0.20.6-0.1
Ambulatory time before self-admin1.82.76.80.40.9-0.8-1.71.71.90.80.9-1.72.1-2.1-1.82.3-2.61.2
Ambulatory time after self-admin0.50.61.9-0.5-0.5-1.2-0.20.2-0.3-0.4-0.3-1.40.5-0.5-1.30.7-1.00.9
Bone: tissue strength1.91.94.40.70.9-0.4-1.71.81.10.50.5-1.11.7-1.5-0.91.9-2.12.1
Total heroin consumption0.40.51.5-0.10.20.70.2-0.2-0.5-0.1-0.31.0-1.10.91.2-0.80.90.9
Bone: trabecular number1.82.95.91.52.10.9-2.42.41.81.71.7-0.1-0.2-2.4-0.52.4-2.10.3
Bone: trabecular spacing0.71.02.4-0.4-1.2-0.11.1-1.1-0.7-0.7-0.80.5-0.71.60.9-1.51.30.7
Bone: trabecular thickness0.20.30.90.00.2-0.3-0.50.5-0.00.10.1-0.70.5-0.6-0.70.9-0.90.5
Bone: trabecular tissue density0.81.23.1-1.8-1.4-1.41.3-1.3-0.8-1.3-1.2-1.00.41.0-0.9-0.60.20.2
Water consumed over 24 hours0.30.30.8-0.8-0.3-0.30.7-0.7-0.5-0.7-0.70.20.90.50.3-0.70.70.2
Number of responses in last shaping day1.31.42.9-1.2-1.2-1.71.0-1.0-1.1-1.5-1.4-1.61.40.6-1.3-0.7-0.0-0.0