Hub : Genes

Iqgap2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver gene expression Iqgap2 0.06 0.04 8.2e-05 0.02 0.03 0.03 0.03 1.6e-03 3.1e-04 9.2e-05 1.7e-04
2 Adipose alternative TSS NM_001427125.1 0.04 0.04 4.3e-03 0.01 0.01 0.01 0.01 8.4e-03 4.8e-02 3.6e-02 2.5e-02
3 Adipose alternative TSS XM_063281081.1 0.04 0.03 2.7e-03 0.02 0.01 0 0.01 5.6e-03 3.8e-02 1.7e-01 1.3e-02
4 Adipose gene expression Iqgap2 0.21 0.08 0.0e+00 0.16 0.16 0.16 0.16 3.1e-17 2.8e-17 2.1e-17 3.2e-17
5 BLA gene expression Iqgap2 0.26 0.1 1.3e-15 0.24 0.27 0.27 0.28 3.9e-13 1.0e-14 9.9e-15 4.5e-15
6 Brain gene expression Iqgap2 0.14 0.07 1.1e-16 0.18 0.18 0.18 0.19 7.7e-17 7.3e-17 6.3e-17 1.7e-17
7 RMTg alternative TSS XM_063281081.1 0.21 0.12 3.7e-05 0.16 0.2 0.18 0.22 4.4e-05 5.7e-06 2.0e-05 1.4e-06
8 Liver intron excision ratio chr2_28775200_28852017 0.04 0.03 4.9e-05 0.01 0.02 0.02 0.01 1.5e-02 2.3e-03 2.0e-03 1.0e-02
9 RMTg alternative TSS XM_063281081.1 0.18 0.11 2.3e-04 0.2 0.17 0.14 0.2 3.9e-06 3.6e-05 1.8e-04 4.1e-06
10 Liver intron excision ratio chr2_28833835_28852017 0.05 0.03 4.0e-06 0.02 0.03 0.03 0.02 1.1e-03 2.7e-04 3.1e-04 1.2e-03
11 NAcc mRNA stability Iqgap2 0.05 0.04 5.3e-06 0.03 0.02 0.02 0.02 2.8e-05 1.5e-04 7.4e-04 1.5e-04
12 LHb gene expression Iqgap2 0.2 0.12 9.0e-04 0.01 0.08 0.03 0.06 1.8e-01 5.1e-03 5.7e-02 1.9e-02
13 NAcc intron excision ratio chr2_28775200_28852017 0.06 0.04 7.7e-06 0.02 0.03 0.02 0.02 1.9e-04 7.9e-06 1.1e-04 1.2e-04
14 Liver mRNA stability Iqgap2 0.19 0.08 0.0e+00 0.12 0.15 0.15 0.15 3.0e-13 1.0e-16 5.0e-16 5.8e-16
15 NAcc gene expression Iqgap2 0.23 0.08 0.0e+00 0.31 0.31 0.31 0.31 1.9e-47 1.3e-48 5.1e-48 6.4e-48
16 RMTg alternative TSS NM_001427125.1 0.15 0.1 1.0e-03 0.12 0.14 0.11 0.17 4.7e-04 1.7e-04 6.3e-04 2.8e-05
17 PL gene expression Iqgap2 0.04 0.03 1.1e-04 0.04 0.04 0.04 0.04 1.5e-05 1.5e-05 4.3e-05 1.9e-05
18 RMTg alternative TSS NM_001427125.1 0.17 0.1 3.1e-04 0.07 0.14 0.12 0.13 6.9e-03 1.5e-04 5.8e-04 2.1e-04
19 RMTg isoform ratio NM_001427125.1 0.19 0.1 6.1e-05 0.1 0.2 0.18 0.18 1.3e-03 5.0e-06 1.8e-05 1.7e-05
20 pVTA isoform ratio NM_001427125.1 0.06 0.05 5.2e-03 -0 0.03 0 0 8.8e-01 3.6e-03 3.2e-01 3.0e-01
21 BLA mRNA stability Iqgap2 0.13 0.08 3.9e-05 0.08 0.1 0.09 0.08 3.5e-05 1.0e-05 1.4e-05 3.4e-05
22 Adipose mRNA stability Iqgap2 0.09 0.05 5.8e-09 0.06 0.07 0.06 0.06 2.4e-07 6.3e-08 2.5e-07 3.8e-07
23 PL mRNA stability Iqgap2 0.17 0.11 4.3e-05 0.01 0.04 0.03 0.03 1.2e-02 1.3e-05 5.3e-04 7.5e-04
24 IC mRNA stability Iqgap2 0.16 0.09 4.0e-04 0.07 0.09 0.11 0.08 5.6e-04 2.0e-04 2.2e-05 3.4e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density0.61.13.2-0.7-1.11.11.21.30.81.41.41.8-1.11.11.01.20.90.9-1.30.9-0.9-0.8-1.30.0-0.1-0.3-0.1
Area under the delay curve1.31.64.62.01.3-1.3-0.8-0.7-1.5-0.4-1.60.71.8-0.6-2.1-0.1-0.5-0.7-0.9-2.10.10.21.61.21.51.80.6
BMI with tail1.86.210.83.13.1-3.1-2.9-2.8-2.6-2.8-3.3-2.43.0-2.5-2.9-2.4-2.4-2.61.9-2.82.22.22.9-0.20.21.10.5
BMI without tail1.95.79.22.22.8-2.8-2.7-2.6-2.3-3.0-2.5-3.02.0-2.5-1.6-2.9-2.7-2.72.8-1.22.82.81.9-1.7-1.5-0.6-1.2
Body weight2.29.514.43.73.8-3.8-3.6-3.6-3.3-3.6-3.5-3.33.2-3.2-2.9-3.3-3.4-3.43.0-2.53.23.33.0-1.5-1.1-0.0-0.7
Weight adjusted by age0.00.10.5-0.10.1-0.10.10.00.30.3-0.10.70.00.3-0.0-0.10.2-0.1-0.4-0.0-0.0-0.10.30.20.20.70.0
Bone surface0.10.21.00.3-0.20.20.30.40.00.50.21.00.10.4-0.30.50.30.2-0.9-0.4-0.4-0.4-0.00.60.60.80.5
Bone volume1.01.84.0-1.0-1.51.51.61.71.31.71.52.0-1.21.50.91.71.41.4-1.70.7-1.5-1.5-1.30.80.60.30.7
Breakpoint value in progressive ratio session0.60.72.5-0.4-0.50.50.70.91.00.40.4-0.0-0.11.0-0.20.70.90.7-0.5-0.4-0.9-1.00.21.51.41.61.3
Number of licking bursts0.30.42.50.10.6-0.6-0.7-0.5-0.3-0.9-0.6-1.60.5-0.7-0.4-0.8-0.6-0.51.2-0.40.60.50.7-0.2-0.0-0.20.4
Context. condit. distance diff. score0.80.92.2-1.5-1.01.01.11.10.71.01.11.2-1.11.11.11.00.90.8-0.91.1-0.8-0.8-1.20.0-0.1-0.10.0
Locomotion velocity, session 10.60.72.1-1.0-1.01.00.60.40.90.60.80.6-1.20.51.40.30.50.6-0.21.4-0.3-0.3-1.2-0.7-0.9-1.1-0.6
Locomotion distance, session 11.31.73.9-1.7-1.51.51.21.11.41.01.50.6-1.80.91.90.90.91.2-0.32.0-0.7-0.7-1.9-0.8-1.0-1.6-0.8
Locomotion velocity, session 20.80.92.3-1.1-0.90.91.00.91.00.71.20.7-1.31.11.40.70.60.8-0.41.5-0.5-0.5-1.5-0.5-0.8-1.0-0.4
Locomotion distance, session 21.52.14.2-1.8-1.71.71.51.41.81.21.90.7-2.01.62.11.11.21.4-0.42.0-1.0-1.0-2.0-0.4-0.7-1.2-0.4
Locomotion velocity, session 31.41.63.0-1.6-1.11.11.51.61.31.41.21.7-1.21.61.11.31.51.2-1.51.0-1.3-1.3-1.10.80.50.70.5
Locomotion distance, session 30.60.71.6-0.9-0.60.60.70.70.60.70.21.2-0.30.80.10.91.00.7-1.3-0.1-0.9-1.0-0.11.21.11.30.6
Stereotopy head waving bouts, day 30.81.02.7-1.7-1.01.01.01.11.20.81.20.3-1.41.01.60.40.70.8-0.01.6-0.5-0.5-1.2-0.6-0.7-0.8-0.2
Stereotopy head waving duration, day 30.10.10.2-0.10.3-0.3-0.10.0-0.1-0.1-0.1-0.3-0.0-0.10.2-0.5-0.2-0.30.40.20.30.30.1-0.4-0.4-0.10.1
Locomotion velocity, session 71.41.64.5-0.9-1.21.21.21.30.61.60.82.1-0.71.20.31.71.31.3-2.00.1-1.5-1.5-0.81.21.20.71.1
Locomotion distance, session 70.10.10.2-0.0-0.10.10.10.1-0.30.20.00.40.10.2-0.30.50.10.2-0.4-0.3-0.3-0.3-0.10.40.40.10.4
Stereotopy head waving bouts, day 70.50.62.2-1.5-0.60.60.80.81.00.31.10.2-1.20.91.30.10.60.40.01.4-0.2-0.2-0.8-0.4-0.6-0.0-0.2
Stereotopy head waving duration, day 70.20.20.8-0.9-0.20.20.40.40.70.10.50.2-0.70.50.8-0.10.40.1-0.00.9-0.1-0.1-0.4-0.2-0.40.2-0.1
Locomotion velocity, session 84.35.111.3-2.9-2.32.32.52.52.61.83.11.4-3.22.73.31.51.61.9-0.73.4-1.2-1.1-3.2-1.1-1.6-1.8-0.8
Locomotion distance, session 81.31.94.1-1.8-1.51.51.51.41.31.21.81.3-1.91.52.01.01.01.1-0.72.0-0.8-0.7-2.0-0.7-1.0-1.1-0.7
Degree of sensitization distance0.30.31.60.50.3-0.3-0.4-0.4-0.6-0.5-0.0-0.80.1-0.50.0-0.4-0.8-0.40.90.10.60.7-0.2-1.0-0.9-1.3-0.4
Degree of sensitization stereotypy0.30.41.4-1.2-0.40.40.70.70.90.10.80.1-0.60.90.70.10.70.3-0.20.6-0.3-0.4-0.20.40.20.90.6
Conditioned locomotion0.20.20.50.10.3-0.3-0.5-0.5-0.5-0.4-0.6-0.60.6-0.6-0.6-0.3-0.2-0.30.3-0.60.20.10.70.30.40.20.2
Cocaine response after cond. corrected0.10.10.40.2-0.30.3-0.2-0.40.00.2-0.40.20.3-0.6-0.30.00.20.1-0.2-0.3-0.2-0.20.40.40.40.20.1
Cocaine response after cond. not corrected0.10.20.80.8-0.10.1-0.4-0.6-0.5-0.0-0.40.20.3-0.8-0.2-0.2-0.3-0.30.0-0.20.30.30.2-0.4-0.3-0.5-0.9
Cocaine response before conditioning0.30.32.10.40.2-0.20.00.1-0.6-0.10.30.2-0.30.20.3-0.0-0.5-0.30.10.40.40.5-0.7-1.0-1.0-1.1-1.4
Saline control response1.21.63.11.01.2-1.2-1.4-1.4-1.3-1.5-1.0-1.70.9-1.4-0.6-1.5-1.5-1.41.8-0.41.51.50.8-1.3-1.1-1.0-1.2
Bone: connectivity density0.10.21.0-0.0-0.10.10.40.40.20.50.61.0-0.40.40.40.30.30.1-0.60.4-0.1-0.1-0.5-0.2-0.30.1-0.3
Bone: cortical apparent density2.53.45.4-2.3-2.12.12.12.21.72.01.71.7-1.62.01.32.22.12.2-1.91.0-2.2-2.2-1.51.51.30.51.3
Bone: cortical area0.40.61.7-0.1-0.40.40.70.70.70.70.20.90.00.8-0.30.90.70.7-1.1-0.5-0.9-0.9-0.01.31.31.21.2
Bone: cortical porosity0.10.21.0-0.2-0.00.0-0.1-0.1-0.10.0-0.4-0.40.30.1-0.50.10.10.20.0-0.6-0.2-0.30.50.60.80.51.0
Bone: cortical porosity0.20.21.5-0.4-0.20.20.10.10.10.1-0.3-0.40.20.2-0.40.20.30.30.0-0.5-0.4-0.40.40.80.90.61.2
Bone: cortical thickness0.91.62.7-1.2-1.11.11.31.41.11.30.81.4-0.71.40.31.51.41.4-1.60.1-1.6-1.6-0.61.51.41.01.5
Bone: cortical thickness0.50.61.61.20.8-0.8-0.9-0.8-1.1-0.5-1.3-0.01.1-1.2-1.2-0.3-0.6-0.6-0.1-1.10.40.40.90.20.40.30.2
Bone: cortical tissue density2.53.45.4-2.3-2.12.12.12.21.72.01.71.8-1.62.01.32.22.12.2-1.91.0-2.2-2.2-1.61.51.20.41.2
Condit. Reinf. active minus inactive responses0.20.20.7-0.5-0.10.10.20.20.3-0.40.6-0.8-0.50.20.6-0.3-0.2-0.10.80.60.30.3-0.4-0.7-0.7-0.7-0.4
Condit. Reinf. active-inactive response ratio0.40.41.3-0.40.2-0.2-0.2-0.10.1-0.70.3-1.1-0.3-0.20.6-0.7-0.5-0.41.10.70.70.7-0.3-1.1-1.1-1.0-0.7
Condit. Reinf. active responses0.10.20.6-0.1-0.20.20.30.30.2-0.20.7-0.7-0.40.30.40.1-0.20.10.60.40.10.2-0.6-0.6-0.6-0.8-0.4
Condit. Reinf. inactive responses0.10.10.50.2-0.40.40.50.40.10.40.60.5-0.30.50.10.70.20.4-0.40.1-0.4-0.3-0.60.10.0-0.2-0.2
Incentive salience index mean0.20.20.70.50.4-0.4-0.2-0.3-0.3-0.70.1-0.80.1-0.0-0.0-0.5-0.6-0.50.80.00.60.6-0.0-0.7-0.7-0.5-0.5
Condit. Reinf. lever presses0.10.10.50.70.3-0.3-0.1-0.1-0.1-0.2-0.10.10.40.3-0.50.1-0.1-0.1-0.1-0.50.00.00.20.30.30.50.3
Condit. Reinf. active minus inactive responses0.10.20.80.2-0.20.20.40.40.10.20.0-0.10.10.3-0.40.70.20.5-0.3-0.6-0.6-0.6-0.00.80.90.30.5
Condit. Reinf. active-inactive response ratio0.10.10.40.70.2-0.2-0.00.2-0.4-0.3-0.2-0.50.3-0.2-0.50.1-0.4-0.20.3-0.50.10.10.1-0.00.1-0.2-0.4
Condit. Reinf. active responses0.40.51.3-0.2-0.60.60.80.80.40.60.40.6-0.20.8-0.21.10.70.8-0.9-0.4-1.0-1.0-0.31.11.10.60.7
Condit. Reinf. inactive responses0.10.10.40.40.3-0.3-0.0-0.2-0.2-0.1-0.10.20.30.3-0.40.0-0.1-0.1-0.3-0.4-0.00.00.30.30.30.60.4
Condit. Reinf. lever presses0.50.72.00.0-0.60.60.80.6-0.00.80.40.90.00.9-0.51.40.70.9-1.2-0.7-1.1-1.1-0.31.21.40.60.8
Condit. Reinf. lever reinforcers received0.40.61.90.0-0.40.40.70.60.20.60.20.60.10.7-0.51.10.60.7-1.0-0.7-1.0-1.0-0.01.31.40.90.9
Conditioned reinforcement - actives0.81.34.70.10.5-0.5-0.5-0.6-0.5-0.90.4-1.1-0.4-0.50.8-0.9-1.1-0.81.61.01.21.3-0.7-2.2-2.2-2.1-2.1
Conditioned reinforcement - inactives0.10.20.80.50.3-0.3-0.4-0.7-0.2-0.5-0.3-0.60.2-0.9-0.1-0.4-0.4-0.30.5-0.00.30.40.2-0.4-0.3-0.5-0.5
Conditioned locomotion1.72.26.5-1.3-1.31.31.20.90.91.21.80.9-1.90.92.11.00.51.0-0.32.2-0.5-0.4-2.4-1.5-1.7-2.6-2.3
Patch foraging indifference point 0 sec0.71.32.91.41.3-1.3-1.5-1.5-1.2-1.2-1.4-0.91.3-1.7-1.2-1.1-1.2-1.20.9-1.21.11.11.2-0.4-0.2-0.2-0.3
Patch foraging indifference point AUC0.81.12.21.51.2-1.2-1.1-0.9-1.2-1.1-1.4-1.11.4-1.0-1.5-0.8-0.9-1.00.7-1.50.70.71.40.30.50.60.1
Delay disc. indifference point, 0s delay1.21.35.30.9-0.00.00.10.1-0.20.6-0.70.81.00.1-1.50.80.60.4-1.4-1.7-0.9-0.91.22.12.32.01.5
Delay disc. indifference point, 16s delay0.60.72.41.51.0-1.0-0.8-0.6-1.0-0.5-1.00.31.1-0.4-1.2-0.3-0.6-0.7-0.3-1.20.40.41.00.40.50.90.1
Delay disc. indifference point, 2s delay1.11.24.41.30.3-0.3-0.00.1-0.70.4-0.81.01.20.1-1.60.80.30.2-1.3-1.9-0.8-0.71.11.92.12.01.1
Delay disc. indifference point, 24s delay2.22.46.92.61.9-1.9-1.0-0.8-2.0-0.8-1.80.52.2-0.5-2.5-0.4-0.9-1.2-0.7-2.60.50.51.91.11.52.20.7
Delay disc. indifference point, 4s delay0.70.83.11.00.5-0.5-0.1-0.1-0.70.3-0.71.01.00.2-1.20.30.2-0.1-1.2-1.4-0.4-0.31.01.31.51.80.7
Delay disc. indifference point, 8s delay1.21.43.51.91.5-1.5-1.1-1.0-1.6-0.8-1.60.21.7-1.2-1.8-0.6-0.9-1.1-0.3-1.70.60.71.50.40.71.1-0.1
Indifference point function ln k0.30.51.3-0.5-0.50.50.40.30.70.50.90.6-1.00.31.10.20.10.3-0.01.10.00.0-1.1-0.9-1.1-1.1-0.9
Indifference point function log k0.30.51.3-0.5-0.50.50.40.30.70.50.90.6-1.00.31.10.20.10.3-0.01.10.00.0-1.1-0.9-1.1-1.1-0.9
Patch foraging total patch changes 0 sec0.71.32.91.41.3-1.3-1.5-1.5-1.2-1.1-1.4-0.91.3-1.7-1.2-1.0-1.2-1.10.8-1.21.11.01.2-0.4-0.2-0.3-0.3
Patch foraging total patch changes 12 sec1.21.63.51.71.4-1.4-1.2-0.9-1.4-1.2-1.5-1.21.7-1.2-1.8-0.9-1.2-1.10.8-1.90.90.81.70.30.70.70.4
Patch foraging total patch changes 18 sec1.32.05.51.71.4-1.4-1.4-1.2-1.7-1.4-1.8-1.42.0-1.3-2.2-0.7-1.0-1.10.7-2.30.70.62.00.81.20.91.2
Patch foraging total patch changes 24 sec3.05.29.63.12.6-2.6-2.6-2.5-2.7-2.4-2.7-2.02.8-2.6-2.8-2.1-2.3-2.41.7-2.72.02.02.8-0.30.30.7-0.1
Patch foraging total patch changes 6 sec0.81.33.21.81.2-1.2-1.1-0.8-0.9-1.0-1.3-0.61.6-0.8-1.7-0.7-0.8-0.90.3-1.70.60.61.60.70.81.31.0
Patch foraging time to switch 0 sec0.51.06.40.20.1-0.10.30.40.00.2-0.30.70.70.7-0.90.40.60.1-1.0-1.1-0.6-0.71.01.81.72.52.0
Patch foraging water rate 0 sec0.30.72.80.30.3-0.3-0.8-0.8-0.4-0.5-0.3-0.7-0.1-1.10.3-0.8-0.8-0.51.00.50.80.8-0.1-1.4-1.3-1.7-1.5
Patch foraging water rate 12 sec0.20.42.9-0.6-0.70.70.0-0.20.40.30.5-0.4-0.7-0.40.80.10.00.40.40.8-0.1-0.0-0.7-0.8-0.7-1.7-0.6
Patch foraging water rate 18 sec1.32.14.31.31.3-1.3-1.5-1.4-1.4-1.4-1.0-1.50.8-1.8-0.5-1.6-1.8-1.41.7-0.31.71.70.6-1.8-1.5-1.7-2.1
Patch foraging water rate 24 sec0.81.22.31.11.0-1.0-1.1-0.9-1.4-1.1-0.7-1.00.7-1.4-0.6-1.1-1.4-1.11.2-0.41.31.30.5-1.2-1.0-1.1-1.5
Patch foraging water rate 6 sec0.30.42.5-0.2-0.50.50.20.3-0.00.40.60.2-0.7-0.10.70.3-0.10.30.10.8-0.00.0-1.0-0.9-0.9-1.6-1.4
Seeking ratio, delayed vs. immediate footshock0.50.62.50.40.2-0.2-0.5-0.6-0.4-0.50.1-0.8-0.2-0.70.4-0.6-0.7-0.51.00.50.70.8-0.3-1.3-1.3-1.6-1.4
Distance traveled before self-admin0.40.51.50.80.7-0.7-0.4-0.4-0.9-0.3-0.80.11.0-0.3-1.1-0.2-0.3-0.4-0.2-1.20.10.11.00.70.91.10.6
Distance traveled after self-admin1.61.93.61.91.7-1.7-1.7-1.4-1.5-1.4-1.7-0.91.6-1.8-1.5-1.5-1.4-1.50.9-1.41.31.31.6-0.4-0.10.2-0.4
Extensor digitorum longus weight0.10.41.4-0.3-0.40.40.70.90.30.80.41.2-0.40.80.20.80.70.6-1.10.1-0.7-0.7-0.50.60.50.60.2
Bone: elastic displacement1.51.72.9-1.0-1.21.21.31.31.31.40.61.4-0.71.20.31.61.61.5-1.70.1-1.7-1.7-0.61.71.51.01.7
Bone: elastic work0.60.71.5-0.8-0.90.90.80.80.61.20.61.2-0.50.60.41.11.01.0-1.20.3-1.1-1.1-0.50.80.80.40.8
Bone: endosteal estimation0.30.62.11.50.7-0.7-0.7-0.9-0.5-0.7-0.9-0.70.9-0.8-0.9-0.6-0.8-0.70.6-0.90.60.60.8-0.10.10.2-0.1
Bone: endosteal perimeter0.10.31.51.20.5-0.5-0.4-0.60.0-0.5-0.5-0.30.7-0.4-0.7-0.4-0.5-0.50.3-0.70.40.40.60.10.20.4-0.0
Epididymis fat weight2.48.112.92.43.1-3.1-3.2-3.3-2.7-3.3-2.4-3.41.9-3.1-1.2-3.5-3.3-3.33.6-0.73.53.51.7-3.0-2.8-1.7-2.1
Delta time in closed arm before/after self-admin0.60.62.2-0.5-0.50.50.50.30.30.7-0.10.90.00.5-0.30.90.80.8-1.1-0.4-0.9-1.00.11.31.31.01.5
Delta time in open arm before/after self-admin0.00.00.20.4-0.10.1-0.00.10.30.1-0.10.50.1-0.1-0.20.20.00.0-0.4-0.2-0.1-0.10.00.20.10.00.3
Diff in mean of infusions in LGA sessions0.81.01.8-0.8-1.21.21.31.31.11.11.20.8-0.81.30.61.31.01.2-0.90.4-1.2-1.2-0.90.80.80.30.4
Delay discount exponential model param1.41.54.4-2.0-1.31.30.90.71.50.41.6-0.7-1.80.62.00.10.50.80.82.1-0.2-0.2-1.6-1.1-1.4-1.8-0.6
Extinction: sum of active levers before priming0.20.20.70.20.1-0.1-0.2-0.1-0.3-0.3-0.5-0.70.50.2-0.60.0-0.1-0.00.3-0.7-0.1-0.10.50.50.70.50.8
Active lever presses in extinction session 60.60.64.10.70.4-0.4-0.00.3-0.2-0.0-0.20.30.70.6-0.90.00.2-0.2-0.5-1.0-0.2-0.21.01.21.22.01.1
Bone: final force0.50.82.70.2-0.20.20.30.5-0.00.8-0.21.30.50.4-0.80.90.70.5-1.5-1.0-0.9-0.90.51.61.61.61.3
Bone: final moment0.50.92.90.1-0.10.10.20.5-0.10.8-0.31.30.60.4-0.90.90.70.5-1.5-1.1-0.9-0.90.61.61.71.71.4
Food consumed during 24 hour testing period1.31.84.31.21.5-1.5-1.2-1.3-1.5-1.3-1.6-1.11.8-0.7-2.0-0.7-0.9-1.00.5-2.10.60.61.90.91.21.71.1
Glucose2.13.45.4-2.0-2.12.12.01.82.02.22.12.1-2.11.72.02.11.92.1-1.81.8-1.9-1.8-2.30.40.0-0.9-0.0
Heart weight1.62.54.61.52.1-2.1-1.6-1.5-1.5-2.0-1.3-1.91.4-0.9-1.1-2.1-1.8-1.91.8-0.81.91.91.4-1.1-1.00.4-0.3
Delay discount hyperbolic model param1.21.33.9-1.9-1.21.20.70.61.40.41.4-0.6-1.60.51.90.10.50.70.82.0-0.1-0.2-1.5-1.1-1.3-1.7-0.5
Intermittent access intake day 1-15 change0.00.10.7-0.5-0.50.5-0.2-0.4-0.1-0.0-0.1-0.4-0.2-0.40.20.00.10.20.20.3-0.1-0.1-0.2-0.2-0.2-0.8-0.1
Intermittent access intake escalation0.00.00.2-0.3-0.40.4-0.1-0.3-0.10.0-0.1-0.1-0.1-0.10.10.10.10.20.00.1-0.1-0.2-0.1-0.00.0-0.40.1
Intermittent access intake escalation 20.00.00.2-0.4-0.40.4-0.1-0.40.10.1-0.2-0.1-0.1-0.10.10.10.20.3-0.00.1-0.2-0.20.00.10.1-0.30.3
Intermitt. access day 1 inactive lever presses0.51.83.1-1.2-1.41.41.61.51.11.41.01.6-0.71.20.31.61.61.5-1.80.1-1.7-1.7-0.51.71.61.31.0
Intermitt. access day 15 inactive lever presses0.61.34.4-0.3-0.60.60.70.60.71.0-0.01.50.10.6-0.31.11.40.9-1.8-0.5-1.3-1.30.32.01.82.11.6
Intermitt. access escalation Index0.10.20.7-0.4-0.30.30.20.40.40.10.10.20.10.4-0.20.30.40.3-0.4-0.2-0.4-0.50.20.80.70.90.8
Intermittent access day 1 total infusions3.45.59.33.02.8-2.8-2.6-2.6-2.9-2.7-2.4-2.22.4-2.7-2.2-2.3-2.7-2.62.1-2.02.52.52.1-1.3-0.9-0.3-1.4
Intermittent access day 15 total infusions0.81.22.61.41.2-1.2-1.3-1.2-1.6-1.4-1.1-1.11.2-1.0-1.1-1.0-1.2-1.21.0-1.11.11.11.0-0.5-0.3-0.1-0.7
Intermittent access terminal intake (last 3 days)0.91.22.11.01.0-1.0-1.3-1.3-1.4-1.3-1.0-1.30.9-1.2-0.8-1.1-1.2-1.21.3-0.71.21.20.9-0.8-0.6-0.5-0.9
Intermittent access total infusions1.41.73.91.81.5-1.5-1.5-1.3-2.0-1.5-1.3-1.11.4-1.2-1.4-1.1-1.6-1.41.1-1.31.31.31.1-0.8-0.4-0.3-0.7
Intermittent access day 1 locomotion0.60.72.51.41.1-1.1-0.7-0.5-1.6-0.8-0.6-0.10.9-0.7-0.9-0.4-1.1-1.00.3-0.90.80.90.4-0.6-0.4-0.2-1.3
Intermittent access day 15 total locomotion1.32.34.01.81.5-1.5-1.7-1.9-2.0-1.6-1.4-1.31.3-2.0-1.1-1.4-1.8-1.61.4-0.91.61.60.9-1.3-1.1-1.1-1.6
Intermittent access total locomotion0.30.31.81.20.5-0.5-0.4-0.5-1.3-0.3-0.30.00.6-0.5-0.70.2-0.7-0.40.0-0.80.30.40.0-0.3-0.1-0.6-1.0
Intermittent access standard deviation0.10.20.40.50.3-0.3-0.5-0.6-0.4-0.0-0.70.20.5-0.6-0.5-0.2-0.1-0.2-0.2-0.50.10.10.50.30.30.5-0.1
Left kidney weight4.420.327.34.95.2-5.2-5.2-5.1-5.0-5.2-4.7-5.04.4-5.2-3.8-5.0-5.2-5.14.8-3.35.05.04.1-2.9-2.2-1.2-1.9
Right kidney weight4.520.729.15.35.4-5.4-5.3-5.2-5.0-5.3-5.1-5.04.8-5.0-4.3-5.0-5.1-5.04.6-3.84.84.84.5-2.3-1.6-0.3-1.1
Cocaine induced anxiety0.91.36.0-1.0-0.50.51.51.81.30.91.51.5-0.92.50.90.61.00.6-1.10.8-0.7-0.7-0.70.70.31.80.4
Post-drug Anxiety0.50.63.0-0.5-0.10.10.91.10.90.31.30.8-0.91.71.1-0.10.40.0-0.31.20.00.0-0.8-0.4-0.70.7-0.3
Baseline Anxiety0.40.41.80.60.3-0.3-0.6-0.9-0.8-0.5-0.4-0.70.2-0.8-0.1-0.4-0.7-0.50.70.00.60.7-0.0-1.0-0.8-1.3-0.7
Tail length0.83.36.31.31.7-1.7-1.8-1.8-1.4-2.1-1.0-2.30.7-1.7-0.2-2.2-2.1-1.92.50.22.32.30.5-2.4-2.3-1.9-2.2
Length with tail1.25.28.21.92.3-2.3-2.5-2.6-2.0-2.4-1.7-2.31.2-2.6-0.6-2.8-2.7-2.52.7-0.12.82.91.0-2.8-2.7-2.1-2.4
Length without tail1.03.15.22.22.1-2.1-2.1-2.3-2.2-1.8-2.0-1.31.8-2.1-1.5-1.8-2.0-2.01.4-1.31.91.91.5-1.2-1.0-0.5-0.8
Times rat made contact with spout2.42.75.71.31.7-1.7-1.9-2.1-1.7-2.0-1.4-2.41.5-1.7-1.2-1.9-1.9-1.82.2-1.01.91.81.5-1.2-0.9-0.6-0.7
Lifetime Intake1.51.93.81.81.6-1.6-1.6-1.4-2.0-1.6-1.4-1.21.5-1.3-1.5-1.2-1.6-1.51.1-1.41.41.41.2-0.7-0.4-0.1-0.5
Liver weight, left4.87.912.13.43.4-3.4-3.1-3.1-3.5-3.2-3.4-2.83.2-3.0-3.1-2.7-3.1-3.12.4-2.92.72.72.9-0.9-0.30.3-0.7
Liver weight, right2.03.66.12.52.4-2.4-2.1-2.0-2.4-2.0-2.0-1.52.0-2.0-1.8-1.9-2.2-2.21.5-1.62.02.01.7-1.0-0.7-0.1-1.1
Locomotor activity0.00.10.3-0.50.2-0.2-0.10.20.1-0.30.0-0.1-0.1-0.20.2-0.30.0-0.20.10.20.20.20.1-0.0-0.10.3-0.4
Locomotor testing distance0.40.71.30.51.0-1.0-1.0-0.8-0.9-1.1-1.0-0.70.9-1.1-0.7-1.1-0.7-1.00.6-0.60.90.91.0-0.2-0.10.6-0.5
Locomotor testing rearing0.20.31.00.50.5-0.5-0.6-0.3-0.4-0.5-0.7-0.20.7-0.8-0.7-0.6-0.3-0.50.1-0.70.40.31.00.40.40.8-0.6
Locomotion in novel chamber0.40.51.3-1.2-0.90.90.60.41.00.20.8-0.8-0.90.30.90.20.40.70.60.8-0.4-0.4-0.5-0.2-0.2-0.9-0.2
Locomotion in novel chamber post-restriction0.30.42.6-0.4-0.10.1-0.2-0.5-0.2-0.30.3-0.6-0.5-0.10.7-0.3-0.4-0.20.80.80.50.5-0.6-1.2-1.2-1.6-0.4
Fecal boli incidents, locomotor time 10.71.04.10.41.0-1.0-1.0-1.1-0.7-1.4-1.0-2.00.9-1.3-0.7-1.4-0.8-1.01.6-0.61.00.91.4-0.3-0.00.4-0.1
Change in fecal boli incidents, locomotor task1.31.33.0-1.2-1.31.31.31.31.21.11.71.0-1.51.41.51.00.81.0-0.61.5-0.7-0.6-1.7-0.5-0.8-1.0-0.3
Time >=10cm from walls, locomotor time 11.81.97.4-1.2-1.01.00.4-0.00.90.91.20.5-1.7-0.42.2-0.00.30.50.22.40.10.1-1.7-1.9-2.1-2.7-2.3
Bouts of movement, locomotor time 10.80.93.4-0.2-0.40.40.60.50.70.70.01.10.20.6-0.40.71.00.6-1.3-0.7-0.9-1.00.51.71.71.81.4
Total resting periods, locomotor time 10.50.51.8-0.4-0.60.60.70.60.70.90.51.3-0.30.80.20.60.80.6-1.20.0-0.7-0.8-0.00.90.81.10.4
Rest time, locomotor task time 11.21.44.4-2.1-1.01.01.10.81.40.81.60.3-1.80.82.00.30.70.80.12.1-0.3-0.3-1.6-1.0-1.3-1.4-0.7
Distance moved, locomotor task time 10.71.04.82.21.1-1.1-0.9-0.8-1.6-0.7-1.2-0.11.4-0.6-1.7-0.2-1.0-0.80.1-1.70.60.60.90.10.40.30.4
Vertical activity count, locomotor time 10.41.03.51.90.9-0.9-1.0-0.9-1.5-0.9-1.2-0.61.3-0.9-1.5-0.5-1.1-0.90.5-1.50.70.80.9-0.10.20.00.0
Time >=10cm from walls, locomotor time 20.20.31.3-0.0-0.50.50.2-0.00.10.90.41.0-0.6-0.10.60.40.30.4-0.60.6-0.3-0.3-0.7-0.4-0.5-1.0-1.1
Bouts of movement, locomotor time 20.20.31.2-0.5-0.50.50.60.70.40.60.61.1-0.40.70.40.50.60.3-0.80.4-0.4-0.4-0.40.30.10.6-0.3
Total resting periods, locomotor time 20.20.30.9-0.7-0.60.60.70.70.50.60.60.9-0.50.70.50.50.60.3-0.70.4-0.4-0.4-0.50.30.10.6-0.2
Rest time, locomotor task time 20.20.31.0-0.9-0.50.50.10.10.4-0.10.4-0.6-0.70.00.8-0.20.10.20.60.90.10.1-0.5-0.7-0.7-1.00.2
Distance moved, locomotor task time 20.20.21.71.30.5-0.5-0.3-0.3-0.90.0-0.40.50.6-0.0-0.70.2-0.5-0.3-0.4-0.70.10.20.1-0.00.0-0.0-0.5
Vertical activity count, locomotor time 20.30.41.31.00.3-0.3-0.7-0.8-1.1-0.5-0.7-0.70.6-0.8-0.7-0.2-0.7-0.40.5-0.70.40.50.3-0.3-0.1-0.9-1.2
Light reinforcement 10.41.02.60.30.8-0.8-0.8-0.6-0.3-1.2-0.2-1.50.1-0.80.2-1.3-1.1-1.01.60.41.31.30.1-1.5-1.6-1.0-0.8
Light reinforcement 20.71.12.20.81.3-1.3-1.1-0.9-1.0-1.5-0.8-1.30.8-1.0-0.6-1.4-1.2-1.31.4-0.41.31.30.9-0.9-0.80.0-0.3
Bone: marrow area0.30.62.21.50.7-0.7-0.8-0.9-0.5-0.7-0.9-0.71.0-0.8-1.0-0.6-0.8-0.70.6-1.00.70.70.9-0.10.10.2-0.1
Bone: maximum diameter0.71.23.61.71.0-1.0-0.8-0.9-0.7-0.8-1.4-0.51.6-0.7-1.8-0.5-0.6-0.70.1-1.90.30.31.61.01.31.51.0
Bone: maximum force0.20.30.80.50.1-0.1-0.10.1-0.30.5-0.40.90.5-0.0-0.70.40.20.1-0.9-0.8-0.4-0.40.40.80.90.80.7
Bone: maximum moment0.20.31.00.50.1-0.1-0.10.1-0.40.5-0.50.90.6-0.0-0.80.50.20.1-0.9-0.9-0.4-0.40.50.91.00.90.8
Mean time between licks in bursts0.61.42.61.61.5-1.5-1.4-1.4-1.5-1.2-1.4-0.61.3-1.1-1.2-1.2-1.3-1.40.7-1.11.21.21.2-0.5-0.40.3-0.5
Mean num. licks in bursts0.10.20.60.80.5-0.5-0.4-0.6-0.6-0.2-0.40.30.6-0.3-0.6-0.2-0.4-0.5-0.1-0.60.30.40.4-0.00.00.4-0.2
Cd content in liver0.20.31.20.1-0.30.30.20.00.20.4-0.30.40.10.1-0.30.70.50.6-0.7-0.4-0.7-0.70.10.90.90.51.1
Co content in liver0.40.52.4-0.0-0.30.30.30.20.30.00.7-0.3-0.70.30.80.0-0.20.10.60.90.20.3-1.0-1.1-1.2-1.5-1.2
Cu content in liver0.30.31.50.10.1-0.10.40.40.10.30.60.9-0.50.60.7-0.1-0.1-0.2-0.30.80.30.3-0.7-0.8-1.0-0.2-1.2
Fe content in liver0.81.01.9-1.1-1.11.10.91.01.01.00.50.8-0.50.90.31.11.21.2-1.10.1-1.2-1.3-0.31.31.20.81.4
K content in liver0.40.31.41.20.7-0.7-0.3-0.3-0.7-0.4-0.70.10.8-0.1-0.9-0.3-0.5-0.6-0.1-0.90.40.40.60.20.30.70.0
Mg content in liver0.00.00.20.30.2-0.20.10.2-0.1-0.20.0-0.00.20.4-0.20.0-0.1-0.10.0-0.20.00.10.10.20.20.50.2
Mn content in liver2.32.53.6-1.3-1.71.71.81.81.91.71.21.7-1.11.70.71.81.91.7-1.80.5-1.9-1.9-0.81.71.51.31.6
Na content in liver1.01.02.10.81.0-1.0-0.9-1.0-0.8-1.1-0.6-0.90.5-0.6-0.2-1.3-1.3-1.21.30.01.41.40.3-1.4-1.4-0.8-1.3
Rb content in liver0.40.50.90.90.9-0.9-0.7-0.6-0.9-0.9-0.5-0.90.6-0.4-0.6-0.7-0.9-0.80.9-0.50.80.90.5-0.6-0.5-0.2-0.5
Se content in liver1.11.32.5-1.6-1.21.21.21.21.41.31.01.3-1.11.21.01.11.31.2-1.20.9-1.2-1.2-1.00.70.40.40.8
Sr content in liver0.40.30.7-0.3-0.80.80.50.50.60.80.40.7-0.60.30.50.80.60.8-0.60.4-0.7-0.7-0.60.30.2-0.4-0.1
Zn content in liver0.30.41.4-0.10.4-0.4-0.2-0.2-0.4-0.50.1-0.6-0.2-0.10.4-0.7-0.6-0.60.90.60.70.8-0.3-1.2-1.2-0.8-1.0
Bone: minimum diameter0.71.32.7-1.2-1.31.31.41.31.61.31.11.2-1.11.51.01.21.21.3-1.10.8-1.2-1.2-1.00.70.50.30.6
Time in familiar zone, hab. session 10.10.00.20.20.2-0.20.20.2-0.20.00.20.2-0.10.30.10.0-0.3-0.20.00.10.20.3-0.3-0.4-0.4-0.1-0.4
Time in novel zone, hab. session 10.80.82.11.10.9-0.9-1.2-1.2-0.8-0.8-1.2-0.51.0-1.5-0.9-0.9-0.7-0.90.4-0.80.70.71.2-0.00.10.2-0.2
Total zone transitions, hab. session 10.91.22.4-1.3-1.51.51.21.11.11.01.40.7-1.51.11.41.00.91.1-0.51.4-0.8-0.8-1.6-0.3-0.5-1.1-0.3
Total locomotion distance, hab. session 10.60.92.2-1.5-1.31.31.01.00.80.81.20.4-1.20.91.11.00.81.0-0.41.1-0.8-0.8-1.3-0.1-0.2-0.80.1
Locomotion velocity, hab. session 11.11.53.9-2.0-1.61.61.41.41.21.01.70.3-1.61.31.51.21.01.3-0.31.4-1.1-1.0-1.6-0.1-0.2-1.00.3
Time in familiar zone, hab. session 21.61.72.91.71.6-1.6-1.4-1.4-1.6-1.2-1.3-0.61.2-1.4-0.9-1.4-1.5-1.60.9-0.71.51.60.9-1.2-1.0-0.4-1.2
Time in novel zone, hab. session 20.60.61.4-1.0-1.01.00.60.70.90.50.5-0.2-0.40.50.20.80.91.0-0.30.0-1.0-1.1-0.11.11.10.41.2
Total zone transitions, hab. session 20.10.20.80.0-0.10.10.0-0.20.0-0.00.30.1-0.40.10.5-0.1-0.2-0.10.20.60.30.3-0.5-0.8-0.9-0.8-0.6
Total locomotion distance, hab. session 20.10.10.4-0.6-0.50.50.20.00.60.10.4-0.3-0.50.30.50.10.20.30.20.5-0.1-0.1-0.4-0.2-0.2-0.40.4
Locomotion velocity, hab. session 20.10.10.3-0.5-0.50.50.20.00.50.10.3-0.2-0.40.30.40.10.20.30.10.4-0.2-0.2-0.3-0.1-0.1-0.30.5
Novel to familiar place preference ratio0.10.10.3-0.1-0.20.2-0.1-0.00.40.2-0.10.20.0-0.00.0-0.00.40.2-0.3-0.0-0.3-0.30.30.60.50.60.3
Novelty place preference0.10.10.3-0.2-0.10.1-0.2-0.10.40.1-0.2-0.10.1-0.1-0.0-0.20.30.1-0.1-0.0-0.1-0.20.40.50.40.60.4
Time in novel zone, NPP test0.10.10.4-0.5-0.40.40.10.10.60.30.1-0.0-0.20.10.3-0.00.50.4-0.10.3-0.3-0.40.20.40.30.40.4
Total zone transitions, NPP test0.81.12.3-1.2-1.21.21.41.31.11.01.40.9-1.11.51.01.11.01.1-0.80.9-1.0-1.0-1.20.30.2-0.10.4
Total locomotion distance, NPP test1.21.63.8-2.0-1.61.61.51.51.61.01.70.6-1.51.61.41.21.21.4-0.61.3-1.2-1.2-1.40.30.1-0.20.5
Locomotion velocity, NPP test0.81.12.3-1.5-1.21.21.31.41.20.81.40.6-1.11.50.91.11.11.1-0.70.8-1.0-1.1-1.00.60.50.30.9
Intraocular pressure5.37.612.2-3.4-3.53.53.12.83.23.13.42.5-3.52.83.42.62.72.9-1.93.2-2.4-2.4-3.30.2-0.3-1.2-0.1
Delta distance traveled before/after self-admin1.01.12.21.51.2-1.2-1.3-1.0-0.9-1.1-1.2-0.81.1-1.3-1.0-1.1-1.1-1.10.8-1.01.11.11.1-0.4-0.20.0-0.3
Delta ambulatory time before/after self-admin0.91.11.91.01.1-1.1-1.2-1.1-1.0-1.2-1.0-1.00.8-1.4-0.7-1.1-1.3-1.11.1-0.51.21.20.7-1.0-0.8-0.8-1.0
Parametrial fat weight0.20.42.9-0.3-0.20.2-0.1-0.1-0.2-0.30.2-1.3-0.4-0.10.5-0.2-0.40.01.20.70.30.4-0.6-1.1-1.0-1.7-0.7
Pavlov. Cond. lever latency0.50.71.2-1.0-0.80.81.01.10.90.90.90.9-1.00.90.90.90.80.9-0.80.9-0.8-0.8-1.00.1-0.0-0.2-0.1
Pavlov. Cond. magazine entry latency1.72.24.51.21.5-1.5-1.4-1.5-1.3-1.8-0.7-1.90.8-1.2-0.4-1.9-1.8-1.72.1-0.21.91.90.7-1.8-1.7-1.1-1.3
Pavlov. Cond. change in total contacts0.20.20.90.30.2-0.2-0.2-0.3-0.3-0.60.2-0.90.00.00.1-0.5-0.6-0.40.90.10.60.6-0.0-0.7-0.7-0.7-0.3
Pavlov. Cond. index score1.21.52.71.31.3-1.3-1.4-1.5-1.3-1.5-1.0-1.71.1-1.3-0.9-1.5-1.4-1.41.6-0.81.41.41.1-0.9-0.7-0.4-0.5
Pavlov. Cond. latency score1.21.52.71.21.2-1.2-1.4-1.5-1.3-1.4-1.0-1.71.0-1.3-0.8-1.5-1.4-1.31.6-0.71.41.41.1-1.0-0.7-0.5-0.6
Pavlov. Cond. lever contacts0.10.10.30.40.2-0.2-0.4-0.5-0.4-0.4-0.2-0.50.3-0.2-0.2-0.4-0.4-0.40.5-0.20.40.40.3-0.3-0.2-0.2-0.0
Pavlov. Cond. magazine entry number3.03.76.8-1.9-2.02.02.12.11.92.41.52.6-1.41.91.12.32.32.2-2.60.8-2.3-2.3-1.31.91.61.11.4
Pavlov. Cond. intertrial magazine entries1.41.74.3-1.5-1.11.11.21.31.30.61.70.1-1.91.32.00.60.40.90.32.1-0.3-0.3-2.1-1.3-1.5-1.9-1.0
Pavlov. Cond. lever-magazine prob. diff.0.70.81.31.01.0-1.0-1.0-1.1-1.0-1.1-0.7-1.20.8-0.9-0.7-1.1-1.1-1.11.1-0.61.11.10.8-0.7-0.5-0.2-0.3
Pavlov. Cond. response bias1.41.82.91.51.5-1.5-1.4-1.4-1.3-1.7-1.0-1.71.1-1.1-0.9-1.6-1.6-1.51.7-0.71.61.61.0-1.1-1.0-0.4-0.6
Pavlov. Cond. lever latency0.81.14.10.10.7-0.7-0.7-0.7-0.0-0.8-0.2-0.7-0.3-0.80.8-1.5-0.8-1.01.21.11.31.3-0.1-1.8-2.0-1.1-1.6
Pavlov. Cond. magazine entry latency3.03.69.02.82.0-2.0-1.8-1.9-2.2-1.5-2.4-0.82.7-1.6-3.0-1.0-1.3-1.60.3-3.00.90.92.61.21.52.00.8
Pavlov. Cond. change in total contacts0.91.44.80.5-0.20.20.70.6-0.10.8-0.11.30.60.9-1.21.50.70.8-1.7-1.5-1.3-1.20.32.12.21.91.7
Pavlov. Cond. index score1.21.65.41.40.6-0.6-0.2-0.3-1.0-0.0-1.10.51.6-0.0-2.10.70.0-0.0-1.1-2.3-0.6-0.61.32.02.32.11.7
Pavlov. Cond. latency score1.52.07.01.80.9-0.9-0.5-0.6-1.3-0.4-1.40.21.9-0.2-2.40.4-0.2-0.3-0.9-2.6-0.4-0.41.72.02.32.31.7
Pavlov. Cond. lever contacts1.01.45.1-0.1-0.70.70.90.80.10.90.20.90.31.0-0.91.71.01.1-1.5-1.2-1.5-1.50.12.12.31.41.8
Pavlov. Cond. magazine entry number2.73.310.1-2.5-1.81.81.31.31.81.32.10.6-2.61.03.00.50.91.10.13.2-0.4-0.4-2.5-1.8-2.1-2.6-1.7
Pavlov. Cond. intertrial magazine entries0.30.41.5-0.8-0.60.60.40.40.80.50.60.4-0.90.31.10.10.40.4-0.11.2-0.2-0.2-0.8-0.6-0.8-0.9-0.7
Pavlov. Cond. lever-magazine prob. diff.1.31.86.21.60.7-0.7-0.4-0.4-1.1-0.2-1.20.41.7-0.1-2.30.6-0.1-0.1-1.0-2.5-0.5-0.51.52.12.32.21.8
Pavlov. Cond. response bias0.81.14.90.3-0.20.20.50.4-0.20.5-0.20.50.70.6-1.31.20.60.7-1.1-1.6-1.1-1.10.62.02.21.61.9
Time in closed arm before self-admin0.30.41.6-0.3-0.40.40.20.10.40.10.8-0.4-0.7-0.00.9-0.10.10.10.51.00.10.1-0.6-0.8-0.8-1.0-1.3
Time in closed arm after self-admin0.20.20.8-0.1-0.20.20.40.30.10.40.20.2-0.00.3-0.20.50.50.4-0.5-0.3-0.6-0.60.20.90.90.80.5
Time in open arm before self-admin1.41.53.41.11.7-1.7-1.2-1.2-1.9-1.3-1.1-0.71.1-1.1-0.8-1.4-1.5-1.51.0-0.61.51.60.8-1.2-1.1-0.2-0.8
Time in open arm after self-admin0.60.61.41.20.9-0.9-1.0-0.8-0.8-0.8-0.90.10.6-1.0-0.4-0.8-1.0-0.90.4-0.21.01.00.2-1.0-1.0-0.6-0.5
Bone: periosteal estimation0.20.41.50.80.1-0.1-0.0-0.10.20.1-0.60.30.70.0-1.00.30.10.1-0.6-1.1-0.4-0.40.71.11.21.21.0
Bone: periosteal perimeter0.10.20.80.90.3-0.3-0.1-0.20.1-0.1-0.50.20.60.1-0.70.1-0.1-0.1-0.4-0.8-0.1-0.10.50.70.70.90.4
Bone: post-yield work0.10.20.50.70.5-0.5-0.5-0.3-0.3-0.4-0.4-0.30.3-0.4-0.2-0.6-0.6-0.60.5-0.10.60.60.2-0.6-0.6-0.2-0.4
Progressive ratio test 1 active lever presses1.21.52.91.71.4-1.4-1.4-1.2-1.7-1.3-1.4-1.01.5-1.5-1.6-0.9-1.3-1.20.8-1.61.01.01.4-0.10.20.30.0
Progressive ratio test 1 breakpoint1.11.32.71.61.3-1.3-1.3-1.1-1.6-1.2-1.3-0.91.5-1.3-1.5-0.8-1.2-1.10.7-1.50.90.91.3-0.10.20.30.0
Progressive ratio test 1 inactive lever presses0.50.71.71.31.0-1.0-0.8-0.7-1.1-0.9-1.0-0.71.1-0.7-1.2-0.6-0.7-0.80.4-1.20.60.61.10.30.40.80.1
Progressive ratio test 2 active lever presses3.03.56.12.52.1-2.1-2.1-2.1-2.3-2.3-1.7-2.11.8-2.0-1.6-1.9-2.1-2.02.0-1.42.02.01.6-1.2-0.9-0.5-1.3
Progressive ratio test 2 breakpoint3.03.46.22.52.0-2.0-2.1-2.1-2.3-2.3-1.7-2.21.7-1.9-1.5-1.9-2.1-2.02.0-1.42.02.01.5-1.2-0.9-0.6-1.3
Progressive ratio test 2 inactive lever presses1.01.63.91.51.3-1.3-1.4-1.5-1.2-1.2-0.8-0.70.7-1.5-0.3-1.5-1.3-1.51.1-0.11.51.50.6-1.5-1.5-0.7-2.0
Incentive Sensitization - Responses2.33.25.22.31.9-1.9-1.9-2.1-1.8-2.2-1.4-2.21.4-1.7-1.1-2.1-2.0-2.02.2-0.92.12.01.3-1.5-1.3-0.8-1.7
Incentive Sensitization - Breakpoint2.43.14.82.21.8-1.8-1.9-2.0-1.8-2.1-1.3-2.21.3-1.7-0.9-2.0-2.0-1.92.2-0.72.02.01.2-1.6-1.4-0.9-1.8
Sum of active levers in priming session hrs 5-61.21.14.0-0.1-0.50.50.80.90.90.90.31.20.11.1-0.40.91.00.7-1.4-0.7-1.0-1.10.41.71.72.01.6
Progressive ratio0.00.00.10.2-0.10.10.0-0.2-0.1-0.0-0.1-0.20.1-0.2-0.20.20.10.10.0-0.2-0.2-0.20.10.20.3-0.10.1
Food seeking constrained by brief footshock0.10.10.50.7-0.00.00.10.00.30.20.10.3-0.20.20.20.2-0.20.1-0.00.20.00.1-0.5-0.4-0.4-0.6-0.6
Seeking ratio, punishment vs. effort0.00.10.30.40.2-0.20.10.50.50.20.10.4-0.00.50.00.1-0.1-0.0-0.20.00.10.1-0.2-0.0-0.20.3-0.0
Retroperitoneal fat weight1.45.913.01.82.2-2.2-2.6-2.8-2.2-2.9-1.9-3.61.3-2.7-0.8-2.9-2.8-2.53.5-0.42.82.81.2-2.8-2.4-2.3-2.0
Reaction time number correct0.71.42.8-0.9-1.41.41.41.31.11.51.41.3-1.21.10.91.71.21.5-1.20.8-1.4-1.4-1.40.50.4-0.60.1
Reaction time mean minus median0.20.41.60.3-0.10.10.30.2-0.00.5-0.10.70.30.4-0.60.60.50.3-0.9-0.7-0.6-0.70.41.21.31.20.7
Reaction time mean minus median AUC0.00.10.50.70.1-0.1-0.2-0.3-0.50.1-0.30.30.4-0.2-0.60.2-0.0-0.0-0.4-0.6-0.1-0.10.30.40.50.2-0.3
Reaction time num false alarms1.21.74.01.11.4-1.4-1.3-1.5-1.1-1.6-0.8-1.90.7-0.9-0.4-1.5-1.6-1.42.0-0.21.61.70.5-1.6-1.4-1.1-0.6
Reaction time num false alarms AUC1.62.54.51.41.7-1.7-1.6-1.7-1.6-1.8-1.0-1.90.8-1.1-0.5-1.8-2.0-1.72.1-0.32.02.00.6-2.0-1.8-1.4-1.2
Reaction time trials correct on left0.71.42.8-0.9-1.41.41.41.31.11.51.41.3-1.21.10.91.71.21.5-1.20.8-1.4-1.4-1.40.50.4-0.60.1
Reaction time trials on left0.91.83.5-1.0-1.61.61.61.41.21.61.51.5-1.31.31.01.91.31.7-1.40.8-1.6-1.5-1.60.60.5-0.60.2
Reaction time mean0.30.51.2-0.5-0.80.80.70.60.40.60.50.3-0.30.60.10.80.90.8-0.7-0.1-1.0-1.0-0.11.11.10.70.6
Reaction time mean AUC0.20.31.0-0.4-0.60.60.50.40.30.50.30.3-0.20.5-0.00.70.70.7-0.6-0.1-0.8-0.80.01.01.00.60.6
Median of all reaction times0.20.30.6-0.6-0.70.70.50.50.40.40.40.1-0.30.40.20.60.70.7-0.40.1-0.7-0.8-0.10.80.80.30.4
Reaction time omissions3.04.410.5-1.6-2.12.12.42.21.22.71.73.2-1.52.41.02.92.32.3-3.10.7-2.6-2.5-1.71.91.70.80.7
Reaction time false alarm rate2.93.96.51.72.2-2.2-2.2-2.3-2.0-2.4-1.6-2.41.4-1.7-0.9-2.5-2.4-2.32.6-0.62.52.51.3-2.1-1.9-1.0-1.1
Reaction time premature initiation rate1.92.74.51.51.9-1.9-1.8-1.7-1.4-1.8-1.4-1.41.1-1.9-0.6-2.1-1.9-2.01.7-0.32.12.10.9-1.8-1.8-0.7-1.7
Reaction time premature initiations0.30.61.90.80.7-0.7-0.7-0.6-0.5-0.6-0.3-0.20.2-0.90.1-0.8-0.8-0.80.60.20.90.9-0.1-1.2-1.2-0.9-1.4
Std. dev. reaction times0.30.51.2-0.2-0.70.70.80.70.30.60.50.6-0.20.8-0.00.90.80.7-0.9-0.2-0.9-0.9-0.11.11.10.80.4
Reaction time trials completed0.91.83.5-1.0-1.61.61.61.41.21.61.51.5-1.31.31.01.91.31.7-1.40.8-1.6-1.5-1.60.60.5-0.60.2
Reaction time trials AUC0.91.83.7-1.0-1.61.61.61.51.21.61.51.5-1.31.31.01.91.41.7-1.40.8-1.6-1.6-1.50.70.6-0.50.3
Run reversals in cocaine runway, females0.90.94.1-0.6-0.10.1-0.10.00.1-0.20.6-0.3-0.8-0.31.1-0.4-0.5-0.30.81.30.70.7-1.0-1.7-1.9-1.9-2.0
Run reversals in cocaine runway, males0.50.52.80.00.5-0.5-0.4-0.40.3-0.2-0.9-0.20.7-0.4-0.8-0.30.2-0.1-0.1-0.8-0.1-0.21.11.11.11.51.7
Latency to leave start box in cocaine runway0.30.42.20.10.1-0.10.40.6-0.20.0-0.00.10.50.6-0.70.50.30.1-0.5-0.8-0.5-0.50.51.21.21.50.6
Latency to leave start box in cocaine runway, F0.10.10.60.20.2-0.20.30.5-0.1-0.30.3-0.50.30.7-0.40.2-0.10.00.1-0.5-0.1-0.10.10.50.60.60.3
Latency to leave start box in cocaine runway, M0.50.42.1-0.2-0.20.20.40.50.10.6-0.11.00.20.2-0.30.50.70.3-1.2-0.4-0.6-0.70.31.21.01.50.4
Std. dev. time between licks in bursts1.72.23.71.91.6-1.6-1.8-1.7-1.8-1.6-1.6-1.41.5-1.9-1.3-1.6-1.7-1.71.4-1.21.61.61.4-0.9-0.6-0.4-1.0
Total sessions with >9 infusions1.21.42.41.41.2-1.2-1.5-1.4-1.5-1.4-1.3-1.31.2-1.6-1.1-1.1-1.3-1.21.2-1.01.21.21.0-0.8-0.5-0.5-0.4
Short access day 1 total inactive lever presses0.30.42.51.60.7-0.7-0.00.4-0.9-0.2-0.10.60.60.5-0.80.2-0.3-0.3-0.6-0.80.00.10.20.40.41.0-0.3
Short access day 10 total inactive lever presses1.02.34.4-1.4-1.51.51.91.91.51.91.82.1-1.52.01.31.71.61.5-1.81.2-1.6-1.5-1.60.80.40.40.2
Short access day 1 total infusions0.60.82.31.00.8-0.8-1.1-1.1-1.2-1.0-1.0-0.70.8-1.5-0.7-0.7-1.0-0.80.7-0.60.90.80.6-0.6-0.4-0.7-0.6
Short access day 10 total infusions0.50.72.21.00.8-0.8-0.8-0.6-1.4-0.8-1.0-0.71.2-0.7-1.4-0.1-0.7-0.50.3-1.50.30.30.90.40.70.30.6
Short access total infusions1.01.32.81.51.3-1.3-1.4-1.1-1.7-1.4-1.3-0.91.4-1.2-1.4-0.9-1.3-1.20.8-1.41.11.11.1-0.4-0.10.0-0.1
Short access day 1 locomotion0.20.20.90.40.1-0.1-0.4-0.5-0.6-0.2-0.3-0.10.1-0.9-0.1-0.1-0.4-0.20.2-0.00.30.3-0.1-0.6-0.5-1.0-0.9
Short access day 10 total locomotion1.32.45.2-1.6-1.81.81.81.71.01.81.11.4-0.91.20.32.31.71.9-1.8-0.0-2.1-2.1-0.91.81.90.51.3
Short access total locomotion0.20.20.6-0.4-0.60.60.40.5-0.10.50.40.4-0.30.20.10.80.30.6-0.40.0-0.5-0.5-0.60.10.2-0.6-0.0
One hour access (0.3 mA shock)1.01.12.51.21.0-1.0-1.2-1.6-1.2-1.2-1.0-1.21.0-1.4-0.8-1.1-1.2-1.11.1-0.71.11.10.9-0.7-0.5-0.6-0.8
Compulsive drug intake0.20.20.70.50.6-0.6-0.0-0.0-0.8-0.7-0.1-0.40.40.2-0.4-0.2-0.6-0.60.3-0.40.50.50.1-0.2-0.20.2-0.5
One hour access (shock baseline)0.20.31.00.70.4-0.4-0.8-1.0-0.5-0.3-0.8-0.30.6-1.0-0.7-0.4-0.4-0.40.3-0.60.30.30.7-0.00.2-0.20.1
Social response proportion5.56.39.7-3.1-3.13.12.92.82.62.82.82.5-2.72.82.42.82.82.9-2.32.2-2.7-2.7-2.61.10.7-0.20.6
Social responses2.22.85.8-2.2-2.02.01.71.71.31.62.11.3-2.21.52.21.51.31.6-0.92.2-1.2-1.2-2.4-0.5-0.8-1.7-1.1
Social time4.45.911.3-2.5-2.62.62.82.72.23.02.43.4-2.42.82.03.02.62.7-3.01.8-2.7-2.6-2.61.30.80.20.5
Soleus weight0.30.81.80.40.9-0.9-0.9-0.9-0.5-1.2-0.4-1.30.5-0.8-0.3-1.2-1.0-1.11.3-0.11.11.10.5-0.9-0.9-0.2-0.4
Bone: stiffness0.10.10.40.50.3-0.3-0.5-0.3-0.6-0.1-0.50.10.5-0.4-0.6-0.1-0.2-0.3-0.1-0.60.10.10.50.20.30.30.2
Tibialis anterior weight2.37.915.8-4.0-3.23.23.43.63.22.83.52.2-3.43.23.32.72.82.9-2.03.1-2.6-2.5-3.20.50.1-0.60.4
Time to tail flick, vehicle, before self-admin0.40.41.61.30.9-0.9-0.10.3-0.4-0.5-0.20.00.80.6-1.0-0.1-0.5-0.5-0.1-1.00.20.30.50.40.51.10.4
Time to tail flick, vehicle, after self-admin0.70.91.81.21.2-1.2-0.9-0.8-1.4-0.8-1.2-0.31.3-0.7-1.3-0.8-0.8-1.10.3-1.20.80.81.20.20.31.00.1
Time to tail flick, test, before self-admin2.12.29.50.60.0-0.00.10.2-0.20.4-1.10.51.30.1-1.91.00.80.6-1.4-2.2-1.2-1.31.52.93.12.62.5
Time to tail flick, test, after self-admin1.21.23.0-1.5-1.11.11.31.31.50.91.70.7-1.51.31.60.50.70.8-0.31.6-0.5-0.5-1.4-0.5-0.7-0.7-0.7
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.3-0.10.1-0.2-0.1-0.10.1-0.40.10.2-0.3-0.2-0.20.2-0.1-0.2-0.1-0.1-0.10.50.40.30.60.4
Delta time to tail flick, test, before/after SA3.43.510.6-1.9-1.41.41.51.31.81.02.50.7-2.61.33.10.30.50.70.33.3-0.00.1-2.7-2.3-2.7-2.6-2.3
Tibia length0.30.83.00.90.8-0.8-0.9-0.9-0.8-1.3-0.7-1.70.9-0.9-0.9-0.9-1.0-0.81.4-0.80.90.90.9-0.3-0.1-0.2-0.1
Ambulatory time before self-admin0.40.61.81.00.8-0.8-0.6-0.6-1.0-0.5-1.0-0.21.1-0.5-1.3-0.3-0.4-0.5-0.0-1.30.20.21.20.70.91.00.8
Ambulatory time after self-admin0.91.02.41.41.2-1.2-1.0-0.9-1.2-1.0-1.3-0.61.4-1.2-1.5-0.7-1.0-0.90.4-1.50.70.71.30.20.50.40.1
Bone: tissue strength0.10.10.4-0.6-0.40.40.30.30.10.30.50.1-0.50.30.50.40.20.4-0.00.5-0.2-0.2-0.6-0.2-0.3-0.6-0.1
Total heroin consumption1.01.11.8-1.1-1.21.21.21.31.21.01.10.6-0.81.30.51.31.21.3-0.90.3-1.3-1.3-0.61.21.10.61.1
Bone: trabecular number0.10.21.0-0.1-0.20.20.30.40.10.50.71.0-0.40.30.40.30.20.1-0.60.5-0.1-0.1-0.6-0.3-0.4-0.2-0.4
Bone: trabecular spacing0.50.72.90.30.2-0.2-0.1-0.10.1-0.2-1.0-0.20.8-0.1-1.00.20.40.2-0.4-1.2-0.5-0.61.11.61.71.71.5
Bone: trabecular thickness3.34.16.4-2.5-2.52.52.22.22.02.42.42.3-2.51.82.42.01.92.1-1.72.3-1.8-1.7-2.5-0.0-0.3-1.1-0.2
Bone: trabecular tissue density0.30.40.7-0.8-0.70.70.60.70.40.60.30.7-0.40.50.30.60.80.6-0.80.2-0.7-0.7-0.20.70.60.50.6
Water consumed over 24 hours1.52.03.51.51.6-1.6-1.7-1.7-1.6-1.7-1.5-1.91.6-1.4-1.5-1.5-1.5-1.51.6-1.41.41.41.5-0.5-0.20.00.0
Number of responses in last shaping day0.80.92.21.40.7-0.7-1.0-0.9-0.9-0.3-1.50.41.3-1.4-1.4-0.2-0.3-0.4-0.5-1.50.10.11.20.81.00.90.7