Hub : Genes

Inf2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC alternative polyA XM_063262154.1 0.11 0.09 5.9e-03 0.07 0.05 0.08 0.05 1.2e-02 2.3e-02 6.3e-03 2.2e-02
2 OFC alternative polyA NM_001427264.1 0.1 0.08 9.0e-03 0.05 0.06 0.06 0.04 2.9e-02 1.8e-02 1.2e-02 3.1e-02
3 IL alternative polyA XM_063262154.1 0.19 0.18 7.1e-03 0.1 0.07 0.07 0.08 1.9e-03 7.5e-03 8.2e-03 5.6e-03
4 Liver gene expression Inf2 0.11 0.06 1.1e-16 0.11 0.13 0.12 0.12 6.2e-12 2.9e-14 2.5e-13 2.6e-13
5 PL gene expression Inf2 0.04 0.03 8.8e-05 0.03 0.04 0.03 0.03 3.9e-04 3.9e-05 1.1e-04 1.5e-04
6 pVTA gene expression Inf2 0.04 0.03 7.3e-04 0.03 0.04 0.03 0.03 9.0e-04 6.0e-04 1.4e-03 2.2e-03
7 Adipose alternative polyA NM_001427264.1 0.03 0.04 9.6e-03 0.01 0.01 0.01 0.01 1.1e-02 3.7e-02 3.9e-02 2.6e-02
8 LHb mRNA stability Inf2 0.11 0.09 7.4e-03 0.06 0.05 0.01 0.04 1.7e-02 3.1e-02 1.6e-01 3.9e-02
9 Liver isoform ratio XR_005506358.2 0.03 0.03 3.5e-03 0.01 0 -0 0 4.0e-02 2.2e-01 7.1e-01 7.4e-02
10 NAcc gene expression Inf2 0.13 0.08 5.6e-17 0.11 0.12 0.11 0.12 6.2e-16 3.9e-17 8.4e-17 1.4e-17
11 pVTA mRNA stability Inf2 0.05 0.04 6.0e-05 0.06 0.05 0.04 0.05 1.6e-05 7.9e-05 3.7e-04 3.7e-05
12 IL gene expression Inf2 0.22 0.16 2.3e-04 0.1 0.15 0.11 0.11 1.8e-03 2.0e-04 1.5e-03 1.1e-03
13 Brain mRNA stability Inf2 0.08 0.06 1.0e-05 0.05 0.04 0.05 0.05 1.2e-05 5.0e-05 3.2e-05 2.5e-05
14 Eye mRNA stability Inf2 0.36 0.2 4.4e-04 0.28 0.26 0.24 0.25 4.0e-05 5.6e-05 1.3e-04 9.2e-05
15 Adipose gene expression Inf2 0.09 0.07 2.7e-09 0.07 0.07 0.07 0.07 1.9e-08 6.1e-08 5.2e-08 8.3e-08
16 NAcc mRNA stability Inf2 0.02 0.02 1.2e-03 0.01 0.02 0.01 0.01 2.1e-03 1.6e-03 5.8e-03 3.8e-03
17 PL mRNA stability Inf2 0.04 0.03 2.5e-04 0.04 0.04 0.02 0.03 9.9e-05 8.7e-05 6.9e-03 1.6e-04
18 Adipose isoform ratio XM_063262152.1 0.1 0.08 2.9e-04 0.02 0.02 0.02 0.02 1.9e-03 1.7e-03 5.0e-03 2.2e-03
19 Brain alternative polyA XM_063262154.1 0.02 0.02 7.3e-03 0.01 0 0.02 0.01 3.0e-02 2.4e-01 3.0e-03 5.8e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.10.33.2-0.30.2-0.7-0.10.1-0.0-0.4-0.2-0.20.10.5-0.2-0.1-0.1-0.00.30.30.3-1.8
Area under the delay curve0.40.42.01.4-1.20.80.8-0.80.7-0.40.10.10.40.4-0.20.30.30.30.20.0-0.1-1.0
BMI with tail2.910.012.83.1-3.33.03.3-3.33.4-3.63.03.03.43.5-3.33.13.13.03.33.33.1-1.0
BMI without tail1.85.48.82.5-2.62.22.5-2.52.5-3.02.02.02.52.6-2.42.12.11.92.42.42.2-0.8
Body weight0.52.35.3-2.32.2-2.3-1.91.8-1.71.0-1.8-1.8-1.0-1.11.1-1.4-1.4-1.6-1.0-0.9-0.90.4
Weight adjusted by age0.30.40.7-0.80.8-0.5-0.70.7-0.70.6-0.8-0.8-0.5-0.60.6-0.5-0.5-0.7-0.6-0.6-0.60.6
Bone surface0.10.11.50.5-0.50.20.3-0.30.3-0.40.10.10.30.4-0.2-0.0-0.00.10.20.20.1-1.2
Bone volume0.10.22.40.5-0.40.20.2-0.20.2-0.4-0.1-0.10.10.4-0.1-0.2-0.2-0.10.10.1-0.0-1.6
Breakpoint value in progressive ratio session0.20.20.8-0.90.7-0.6-0.20.1-0.0-0.20.20.20.30.3-0.40.50.50.40.50.50.7-0.1
Number of licking bursts0.20.31.21.1-0.91.10.7-0.60.5-0.30.50.50.10.3-0.10.20.20.20.0-0.0-0.10.8
Context. condit. distance diff. score3.44.15.8-2.22.2-1.9-2.22.2-2.22.4-2.0-2.0-1.9-2.22.0-2.0-2.0-2.1-2.0-2.0-1.90.3
Locomotion velocity, session 10.10.20.4-0.40.4-0.4-0.40.4-0.40.7-0.4-0.4-0.3-0.50.4-0.2-0.2-0.3-0.4-0.4-0.3-0.5
Locomotion distance, session 10.60.81.20.3-0.50.20.8-0.80.8-0.70.90.91.01.0-1.01.01.01.11.01.01.1-1.0
Locomotion velocity, session 20.10.10.50.6-0.40.70.3-0.20.20.20.20.20.0-0.10.00.10.10.2-0.1-0.1-0.2-0.5
Locomotion distance, session 20.30.41.10.9-0.81.10.8-0.70.7-0.50.60.60.60.6-0.50.50.50.60.50.50.4-0.8
Locomotion velocity, session 30.10.21.3-0.1-0.0-0.00.2-0.20.2-0.40.30.30.40.4-0.40.30.30.30.40.40.4-1.2
Locomotion distance, session 30.10.11.30.1-0.10.20.0-0.00.0-0.10.10.1-0.0-0.00.0-0.0-0.0-0.0-0.1-0.1-0.1-1.2
Stereotopy head waving bouts, day 30.10.10.6-0.20.3-0.2-0.20.2-0.20.2-0.2-0.2-0.3-0.00.2-0.3-0.3-0.2-0.2-0.2-0.10.8
Stereotopy head waving duration, day 30.20.21.0-0.30.4-0.3-0.40.4-0.40.5-0.5-0.5-0.6-0.30.5-0.5-0.5-0.4-0.4-0.4-0.41.0
Locomotion velocity, session 70.30.30.6-0.20.0-0.10.2-0.30.3-0.70.50.50.50.5-0.60.60.60.60.60.70.80.8
Locomotion distance, session 70.70.81.31.0-1.01.11.0-1.01.0-1.01.01.00.90.8-0.90.90.90.90.90.80.80.3
Stereotopy head waving bouts, day 71.31.53.9-1.61.5-2.0-1.41.3-1.31.1-1.4-1.4-1.0-0.91.0-1.1-1.1-1.1-0.9-0.8-0.7-0.7
Stereotopy head waving duration, day 70.70.82.9-1.41.3-1.7-1.11.0-1.00.9-1.0-1.0-0.7-0.60.6-0.7-0.7-0.7-0.5-0.5-0.4-0.7
Locomotion velocity, session 81.11.43.1-1.81.6-1.5-1.41.4-1.31.2-1.1-1.1-0.9-1.10.9-1.0-1.0-1.0-0.9-0.8-0.80.0
Locomotion distance, session 80.30.40.9-1.00.8-0.7-0.70.8-0.70.9-0.5-0.5-0.3-0.60.4-0.6-0.6-0.5-0.4-0.4-0.4-0.6
Degree of sensitization distance0.30.32.50.5-0.50.40.5-0.50.5-0.40.40.40.40.4-0.40.50.50.50.40.40.41.6
Degree of sensitization stereotypy0.50.51.7-1.00.9-1.3-0.90.8-0.80.6-0.9-0.9-0.5-0.50.5-0.6-0.6-0.7-0.4-0.4-0.3-0.7
Conditioned locomotion1.21.42.2-1.51.5-1.4-1.31.3-1.30.9-1.2-1.2-1.1-1.21.1-1.1-1.1-1.1-1.1-1.0-1.00.9
Cocaine response after cond. corrected0.80.92.1-0.30.0-0.20.6-0.70.8-1.00.90.91.01.2-1.21.11.11.21.31.31.50.2
Cocaine response after cond. not corrected1.92.23.90.4-0.60.71.3-1.31.4-1.71.51.51.61.8-1.81.61.61.71.81.92.0-0.1
Cocaine response before conditioning1.82.24.92.0-2.02.21.6-1.61.6-1.61.41.41.41.4-1.31.21.21.21.21.21.0-0.6
Saline control response0.20.33.3-0.60.5-0.5-0.40.4-0.3-0.1-0.4-0.4-0.0-0.10.1-0.4-0.4-0.50.00.0-0.1-1.8
Bone: connectivity density0.30.51.8-0.80.7-1.2-0.80.8-0.70.5-0.7-0.7-0.4-0.50.5-0.7-0.7-0.5-0.5-0.5-0.5-1.3
Bone: cortical apparent density6.58.913.8-2.42.7-2.3-2.82.8-2.93.7-2.9-2.9-3.3-3.03.1-2.9-2.9-2.9-3.1-3.1-3.03.3
Bone: cortical area0.20.30.6-0.80.8-0.6-0.50.5-0.50.6-0.5-0.5-0.5-0.30.4-0.4-0.4-0.5-0.4-0.3-0.30.4
Bone: cortical porosity0.60.60.9-0.70.7-0.7-0.90.9-0.90.2-0.9-0.9-0.6-0.70.8-0.9-0.9-1.0-0.8-0.8-0.9-0.8
Bone: cortical porosity0.10.10.4-0.40.3-0.3-0.40.4-0.3-0.4-0.2-0.20.1-0.00.1-0.2-0.2-0.3-0.1-0.0-0.1-0.7
Bone: cortical thickness0.30.62.2-1.51.4-1.4-0.80.7-0.70.5-0.7-0.7-0.6-0.20.3-0.5-0.5-0.5-0.2-0.2-0.00.5
Bone: cortical thickness0.91.11.7-0.91.0-0.8-1.01.0-1.01.0-1.2-1.2-1.2-0.91.1-1.3-1.3-1.3-1.0-0.9-1.00.5
Bone: cortical tissue density6.48.613.6-2.42.6-2.2-2.82.8-2.93.7-2.9-2.9-3.2-3.03.1-2.9-2.9-2.8-3.1-3.1-3.03.3
Condit. Reinf. active minus inactive responses0.60.71.20.5-0.60.20.8-0.80.8-1.10.70.70.91.1-1.00.80.80.81.01.01.00.3
Condit. Reinf. active-inactive response ratio2.62.83.61.4-1.51.11.7-1.71.7-1.91.71.71.91.8-1.81.91.91.81.81.81.8-0.1
Condit. Reinf. active responses0.20.20.7-0.20.1-0.50.2-0.20.3-0.50.20.20.40.7-0.60.40.40.30.70.70.80.8
Condit. Reinf. inactive responses1.61.93.2-1.81.8-1.8-1.51.5-1.51.6-1.4-1.4-1.4-1.11.2-1.3-1.3-1.3-1.1-1.1-0.90.8
Incentive salience index mean0.50.61.5-0.0-0.2-0.30.5-0.60.6-1.10.60.60.81.1-1.00.80.80.81.11.21.20.3
Condit. Reinf. lever presses0.20.30.8-0.50.3-0.50.1-0.10.2-0.60.30.30.50.6-0.60.50.50.40.70.80.90.7
Condit. Reinf. active minus inactive responses0.81.11.6-0.70.7-0.6-1.01.0-1.01.3-1.2-1.2-0.9-1.01.1-1.1-1.1-1.2-1.1-1.1-1.1-1.2
Condit. Reinf. active-inactive response ratio0.70.81.8-0.40.5-0.3-0.70.8-0.81.3-1.0-1.0-0.9-1.01.0-1.0-1.0-1.0-1.0-1.1-1.1-0.4
Condit. Reinf. active responses0.10.21.90.1-0.10.2-0.10.2-0.20.4-0.5-0.5-0.2-0.20.3-0.4-0.4-0.5-0.3-0.3-0.4-1.4
Condit. Reinf. inactive responses0.40.61.10.8-0.90.70.8-0.80.8-0.90.60.60.70.9-0.80.50.50.50.80.80.7-1.1
Condit. Reinf. lever presses1.21.73.91.9-1.92.01.4-1.31.3-1.01.21.21.20.9-0.90.90.90.90.90.80.6-1.9
Condit. Reinf. lever reinforcers received0.20.32.60.1-0.00.1-0.30.3-0.30.5-0.6-0.6-0.3-0.40.5-0.6-0.6-0.7-0.5-0.5-0.6-1.6
Conditioned reinforcement - actives0.40.71.1-0.30.5-0.2-0.60.6-0.70.9-1.1-1.1-1.0-0.70.9-1.0-1.0-1.0-0.8-0.8-0.9-0.7
Conditioned reinforcement - inactives0.30.41.3-0.60.6-0.8-0.60.6-0.60.5-0.7-0.7-0.6-0.40.5-0.7-0.7-0.7-0.4-0.4-0.4-1.1
Conditioned locomotion0.20.32.9-0.10.00.00.2-0.20.3-0.30.00.00.40.5-0.50.20.20.10.60.60.6-1.7
Patch foraging indifference point 0 sec4.07.412.5-3.53.5-3.5-3.13.0-3.02.3-2.9-2.9-2.7-2.42.4-2.6-2.6-2.4-2.3-2.1-1.91.8
Patch foraging indifference point AUC1.72.48.1-2.82.5-2.9-1.91.8-1.71.2-1.3-1.3-1.2-1.11.0-1.0-1.0-0.9-0.9-0.7-0.41.1
Delay disc. indifference point, 0s delay0.30.40.9-0.40.5-0.7-0.50.5-0.50.4-0.9-0.9-0.6-0.40.5-0.4-0.4-0.8-0.5-0.5-0.5-0.8
Delay disc. indifference point, 16s delay0.50.62.31.5-1.31.31.0-0.90.8-0.20.50.50.40.4-0.30.50.50.50.20.10.0-0.6
Delay disc. indifference point, 2s delay1.01.24.92.2-2.01.81.4-1.31.2-0.90.60.60.50.8-0.50.70.70.80.40.20.1-0.5
Delay disc. indifference point, 24s delay0.40.51.41.2-1.10.90.9-0.90.9-0.70.40.40.70.7-0.50.60.60.40.50.40.40.2
Delay disc. indifference point, 4s delay0.40.41.00.8-0.50.40.00.1-0.20.6-0.8-0.8-0.5-0.60.7-0.7-0.7-0.7-0.8-0.9-1.0-0.7
Delay disc. indifference point, 8s delay0.10.20.80.9-0.90.30.5-0.50.5-0.40.10.10.40.3-0.20.20.20.20.20.1-0.0-0.5
Indifference point function ln k0.91.62.7-0.60.8-0.3-1.11.2-1.21.2-1.4-1.4-1.3-1.41.5-1.6-1.6-1.5-1.5-1.5-1.60.3
Indifference point function log k0.91.62.7-0.60.8-0.3-1.11.2-1.21.2-1.4-1.4-1.3-1.41.5-1.6-1.6-1.5-1.5-1.5-1.60.3
Patch foraging total patch changes 0 sec4.58.514.7-3.83.8-3.7-3.33.2-3.22.5-3.1-3.1-2.9-2.62.6-2.8-2.8-2.6-2.4-2.3-2.11.7
Patch foraging total patch changes 12 sec3.34.37.2-2.32.3-2.7-2.22.2-2.22.0-2.1-2.1-2.2-2.02.0-1.9-1.9-1.9-2.0-2.0-1.81.1
Patch foraging total patch changes 18 sec1.21.84.8-1.71.7-2.2-1.41.4-1.40.8-1.3-1.3-1.4-0.81.1-1.3-1.3-1.0-1.0-0.9-0.71.6
Patch foraging total patch changes 24 sec0.30.61.9-1.41.2-1.4-0.90.8-0.80.4-0.7-0.7-0.6-0.40.4-0.6-0.6-0.5-0.3-0.2-0.10.8
Patch foraging total patch changes 6 sec2.63.911.7-3.43.2-3.4-2.32.2-2.11.6-1.7-1.7-1.7-1.41.3-1.3-1.3-1.3-1.2-1.0-0.72.0
Patch foraging time to switch 0 sec7.214.721.04.5-4.64.14.2-4.14.1-4.03.83.83.93.7-3.73.53.53.63.63.53.2-3.1
Patch foraging water rate 0 sec12.526.234.4-5.75.9-5.1-5.55.4-5.45.1-5.2-5.2-5.4-5.15.1-5.0-5.0-4.9-5.0-4.9-4.53.5
Patch foraging water rate 12 sec6.814.217.9-2.93.3-2.5-3.73.8-3.93.8-3.9-3.9-4.1-4.04.2-3.9-3.9-4.1-4.2-4.2-4.22.5
Patch foraging water rate 18 sec4.16.37.7-2.32.5-1.7-2.62.6-2.62.5-2.7-2.7-2.7-2.52.7-2.4-2.4-2.8-2.7-2.7-2.61.3
Patch foraging water rate 24 sec3.95.56.6-1.92.1-1.2-2.32.3-2.42.6-2.4-2.4-2.5-2.42.5-2.5-2.5-2.5-2.5-2.5-2.52.0
Patch foraging water rate 6 sec4.46.47.6-2.62.8-2.1-2.62.6-2.72.6-2.6-2.6-2.7-2.52.6-2.7-2.7-2.6-2.6-2.5-2.41.1
Seeking ratio, delayed vs. immediate footshock0.40.53.0-0.60.7-0.2-0.60.6-0.60.5-0.7-0.7-0.5-0.30.6-0.6-0.6-0.6-0.6-0.5-0.51.7
Distance traveled before self-admin0.40.60.90.8-0.81.00.9-0.80.8-0.70.60.60.60.8-0.70.80.80.50.70.70.6-0.8
Distance traveled after self-admin0.40.52.1-0.20.3-0.2-0.50.5-0.60.4-0.8-0.8-0.7-0.50.7-0.9-0.9-0.9-0.7-0.7-0.8-1.4
Extensor digitorum longus weight7.027.539.4-6.36.3-6.0-5.95.9-5.85.2-5.5-5.5-5.0-5.25.0-5.0-5.0-5.1-4.8-4.7-4.40.3
Bone: elastic displacement0.40.51.00.4-0.20.0-0.30.4-0.50.3-0.7-0.7-0.8-0.50.8-0.9-0.9-0.9-0.8-0.9-1.0-0.9
Bone: elastic work0.20.21.01.0-0.80.70.2-0.20.10.0-0.1-0.1-0.3-0.20.4-0.3-0.3-0.3-0.5-0.6-0.7-0.0
Bone: endosteal estimation0.40.83.81.9-1.71.91.0-0.90.8-0.20.60.60.60.2-0.20.30.30.20.1-0.0-0.3-0.7
Bone: endosteal perimeter0.10.20.60.6-0.50.70.5-0.50.4-0.00.50.50.40.2-0.30.30.30.30.30.20.2-0.2
Epididymis fat weight2.79.411.72.8-3.02.33.2-3.23.2-3.33.03.03.33.4-3.33.23.23.03.33.33.20.8
Delta time in closed arm before/after self-admin0.10.10.4-0.00.10.4-0.20.2-0.20.2-0.3-0.3-0.0-0.20.2-0.3-0.3-0.3-0.2-0.2-0.30.6
Delta time in open arm before/after self-admin0.50.51.4-1.21.1-1.2-0.80.7-0.70.4-0.8-0.8-0.7-0.40.4-0.2-0.2-0.7-0.4-0.3-0.2-0.7
Diff in mean of infusions in LGA sessions0.20.31.4-1.21.0-0.6-0.30.2-0.2-0.10.00.10.20.2-0.40.40.40.50.40.60.70.0
Delay discount exponential model param0.30.31.8-1.31.2-0.7-0.80.7-0.60.4-0.1-0.1-0.4-0.30.2-0.2-0.2-0.3-0.1-0.00.10.8
Extinction: sum of active levers before priming0.70.81.6-0.30.1-0.70.5-0.50.6-0.70.90.90.90.8-1.01.01.01.11.11.11.31.1
Active lever presses in extinction session 61.71.72.5-1.41.4-1.2-1.41.4-1.41.4-1.2-1.2-1.3-1.61.3-1.2-1.2-1.4-1.3-1.3-1.30.7
Bone: final force0.10.20.60.5-0.30.6-0.10.1-0.20.5-0.2-0.2-0.4-0.50.5-0.5-0.5-0.5-0.6-0.7-0.80.6
Bone: final moment0.10.20.50.3-0.10.4-0.20.2-0.30.5-0.4-0.4-0.4-0.50.6-0.5-0.5-0.6-0.6-0.6-0.70.5
Food consumed during 24 hour testing period0.40.61.1-1.11.0-1.0-0.90.9-0.80.6-0.8-0.8-0.6-0.50.6-0.8-0.8-0.8-0.5-0.5-0.5-1.0
Glucose0.30.41.0-0.10.3-0.4-0.40.4-0.50.5-0.8-0.8-1.0-0.30.8-0.9-0.9-0.7-0.8-0.8-0.80.4
Heart weight0.50.71.1-0.60.7-0.6-0.80.8-0.90.7-0.9-0.9-1.0-0.91.0-1.0-1.0-0.8-1.0-1.0-0.90.2
Delay discount hyperbolic model param0.30.41.9-1.41.2-0.8-0.80.7-0.60.4-0.1-0.1-0.4-0.30.2-0.2-0.2-0.3-0.10.00.10.9
Intermittent access intake day 1-15 change1.63.23.81.6-1.71.61.9-1.91.9-1.72.02.01.91.9-1.91.81.81.81.91.91.9-0.1
Intermittent access intake escalation1.63.23.81.7-1.81.51.9-1.92.0-1.61.91.91.91.9-1.91.81.81.91.91.91.90.1
Intermittent access intake escalation 21.31.41.91.0-1.00.71.2-1.31.3-1.11.31.31.21.3-1.31.31.31.21.31.31.4-0.1
Intermitt. access day 1 inactive lever presses0.20.61.7-0.90.9-1.3-0.90.9-0.90.8-0.5-0.5-0.8-0.80.7-0.6-0.6-0.6-0.7-0.7-0.6-0.3
Intermitt. access day 15 inactive lever presses1.32.65.1-1.81.8-2.2-1.71.7-1.71.3-1.8-1.8-1.6-1.41.5-1.7-1.7-1.7-1.4-1.4-1.3-0.4
Intermitt. access escalation Index0.81.11.7-0.70.8-0.3-1.01.1-1.10.9-1.1-1.1-1.1-1.21.2-1.2-1.2-1.1-1.2-1.2-1.3-0.9
Intermittent access day 1 total infusions0.20.30.80.1-0.20.40.5-0.50.5-0.60.20.20.50.7-0.60.50.50.40.70.70.7-0.9
Intermittent access day 15 total infusions1.21.72.51.1-1.21.31.4-1.41.4-1.31.21.21.41.6-1.51.31.31.31.51.51.4-0.6
Intermittent access terminal intake (last 3 days)1.72.23.41.2-1.31.21.6-1.61.6-1.51.31.31.41.8-1.61.51.51.31.71.71.6-1.2
Intermittent access total infusions0.60.71.20.5-0.60.80.9-0.90.9-0.80.60.60.81.1-1.00.80.80.71.01.01.0-0.7
Intermittent access day 1 locomotion1.21.52.50.5-0.70.91.1-1.11.2-1.21.11.11.41.5-1.51.21.21.21.51.61.6-1.3
Intermittent access day 15 total locomotion0.30.51.50.9-0.91.20.9-0.90.8-0.50.70.70.50.8-0.60.50.50.50.60.60.6-0.2
Intermittent access total locomotion0.60.71.60.3-0.40.50.8-0.80.8-0.90.60.60.81.2-1.00.60.60.61.11.11.1-1.2
Intermittent access standard deviation1.22.54.90.3-0.60.51.2-1.31.4-1.61.41.41.82.0-2.01.81.81.52.12.22.2-0.7
Left kidney weight1.88.210.8-3.33.3-3.1-3.33.3-3.22.5-3.2-3.2-2.6-2.82.7-2.8-2.8-3.0-2.6-2.5-2.5-0.3
Right kidney weight1.36.18.1-2.82.8-2.4-2.82.8-2.82.1-2.7-2.7-2.3-2.62.5-2.2-2.2-2.6-2.4-2.3-2.3-0.3
Cocaine induced anxiety1.21.74.1-1.01.1-0.9-1.21.3-1.31.7-0.9-0.9-1.5-1.61.4-1.1-1.1-1.1-1.5-1.5-1.32.0
Post-drug Anxiety2.72.94.2-1.31.5-1.4-1.71.7-1.72.0-1.5-1.5-2.0-2.01.9-1.6-1.6-1.6-1.9-1.9-1.81.7
Baseline Anxiety0.10.10.80.4-0.40.20.3-0.30.2-0.4-0.0-0.00.10.2-0.10.20.20.00.10.10.1-0.9
Tail length4.617.822.6-4.64.7-4.7-4.64.6-4.53.9-4.6-4.6-4.1-4.14.1-4.4-4.4-4.4-3.9-3.8-3.71.3
Length with tail7.130.943.8-6.66.6-6.6-6.36.2-6.15.3-5.9-5.9-5.3-5.45.2-5.3-5.3-5.5-5.1-4.9-4.61.3
Length without tail3.711.821.3-4.64.5-4.4-4.03.9-3.83.4-3.5-3.5-3.0-3.33.1-2.9-2.9-3.0-3.0-2.8-2.61.4
Times rat made contact with spout0.20.21.2-0.70.7-0.9-0.40.3-0.30.3-0.2-0.2-0.3-0.20.2-0.2-0.2-0.2-0.1-0.10.01.1
Lifetime Intake0.30.40.80.5-0.50.80.7-0.80.7-0.50.50.50.60.9-0.70.60.60.50.70.70.6-0.5
Liver weight, left2.64.46.3-2.52.5-2.5-2.32.2-2.21.9-2.2-2.2-2.1-1.91.9-2.2-2.2-2.1-1.8-1.7-1.60.1
Liver weight, right0.20.32.2-0.30.1-0.20.2-0.20.3-0.50.40.40.60.5-0.60.60.60.40.60.60.6-1.5
Locomotor activity0.20.30.6-0.50.5-0.1-0.50.5-0.60.8-0.5-0.5-0.6-0.60.6-0.4-0.4-0.5-0.6-0.6-0.60.6
Locomotor testing distance0.20.40.7-0.40.4-0.1-0.50.6-0.60.8-0.6-0.6-0.7-0.70.7-0.5-0.5-0.5-0.8-0.8-0.80.5
Locomotor testing rearing1.63.24.41.6-1.72.01.9-1.91.9-1.72.02.01.81.7-1.72.12.11.91.61.61.6-0.2
Locomotion in novel chamber3.74.76.6-1.31.6-1.7-2.02.0-2.12.5-2.2-2.2-2.4-2.42.4-2.5-2.5-2.6-2.4-2.4-2.50.6
Locomotion in novel chamber post-restriction0.00.00.20.5-0.40.40.2-0.10.1-0.3-0.0-0.00.1-0.0-0.0-0.1-0.1-0.10.00.0-0.1-0.1
Fecal boli incidents, locomotor time 11.42.13.70.6-0.90.11.2-1.31.4-1.51.31.31.71.5-1.81.71.71.51.81.91.9-0.4
Change in fecal boli incidents, locomotor task2.02.03.3-1.01.2-0.4-1.31.4-1.41.6-1.2-1.2-1.4-1.41.4-1.8-1.8-1.6-1.4-1.4-1.61.5
Time >=10cm from walls, locomotor time 10.60.62.8-1.71.3-1.2-0.50.4-0.20.00.40.40.40.3-0.60.30.30.50.70.91.01.3
Bouts of movement, locomotor time 11.82.13.61.3-1.40.61.4-1.51.4-1.91.31.31.41.7-1.51.41.41.51.51.51.5-1.5
Total resting periods, locomotor time 11.82.03.41.5-1.60.71.5-1.51.5-1.81.31.31.41.7-1.41.31.31.51.41.41.4-1.3
Rest time, locomotor task time 10.20.21.11.0-0.90.60.5-0.50.4-0.20.20.2-0.20.4-0.0-0.1-0.1-0.0-0.0-0.1-0.10.7
Distance moved, locomotor task time 10.20.30.80.5-0.40.90.5-0.40.40.20.60.60.6-0.1-0.20.80.80.60.10.10.10.9
Vertical activity count, locomotor time 10.10.30.8-0.10.20.3-0.30.4-0.40.9-0.1-0.1-0.5-0.70.7-0.1-0.1-0.0-0.8-0.8-0.80.8
Time >=10cm from walls, locomotor time 20.50.73.1-1.71.4-1.8-1.00.9-0.80.5-0.3-0.3-0.6-0.40.4-0.7-0.7-0.2-0.3-0.20.00.9
Bouts of movement, locomotor time 21.11.73.7-0.00.30.0-0.80.9-1.01.0-1.4-1.4-1.5-1.31.6-1.6-1.6-1.8-1.7-1.8-1.90.1
Total resting periods, locomotor time 20.81.43.10.10.10.2-0.60.7-0.80.9-1.3-1.3-1.4-1.11.4-1.4-1.4-1.6-1.5-1.6-1.8-0.1
Rest time, locomotor task time 20.10.10.30.4-0.20.10.00.0-0.10.4-0.5-0.5-0.4-0.20.4-0.1-0.1-0.3-0.5-0.5-0.5-0.1
Distance moved, locomotor task time 20.30.40.80.4-0.40.60.5-0.50.5-0.40.90.90.60.4-0.50.80.80.80.40.40.50.8
Vertical activity count, locomotor time 20.10.10.4-0.60.5-0.2-0.40.4-0.40.30.10.1-0.4-0.40.4-0.4-0.4-0.1-0.4-0.3-0.20.4
Light reinforcement 10.00.00.1-0.20.20.1-0.20.2-0.20.1-0.1-0.1-0.2-0.20.2-0.3-0.3-0.3-0.1-0.1-0.20.2
Light reinforcement 21.62.53.11.2-1.31.51.6-1.61.6-1.51.71.71.71.6-1.71.81.81.71.71.71.7-0.5
Bone: marrow area0.30.73.61.9-1.71.80.9-0.80.8-0.20.50.50.50.1-0.20.20.20.20.0-0.1-0.3-0.8
Bone: maximum diameter0.20.40.90.2-0.20.50.6-0.70.6-0.40.60.60.50.8-0.60.60.60.60.70.70.80.9
Bone: maximum force0.10.10.80.1-0.00.0-0.10.1-0.20.3-0.2-0.2-0.2-0.30.3-0.3-0.3-0.3-0.3-0.3-0.40.9
Bone: maximum moment0.00.10.5-0.00.1-0.2-0.20.2-0.20.3-0.3-0.3-0.1-0.20.3-0.3-0.3-0.3-0.3-0.3-0.30.7
Mean time between licks in bursts0.20.51.01.0-0.91.00.8-0.70.7-0.60.70.70.80.6-0.60.60.60.60.60.60.4-0.5
Mean num. licks in bursts0.30.52.1-1.41.3-1.5-0.90.8-0.70.4-0.6-0.6-0.2-0.30.2-0.3-0.3-0.3-0.1-0.00.1-0.1
Cd content in liver0.20.20.50.2-0.10.2-0.20.3-0.30.3-0.5-0.5-0.4-0.60.5-0.6-0.6-0.6-0.6-0.6-0.7-0.6
Co content in liver1.21.42.1-1.01.1-1.2-1.21.2-1.21.4-1.1-1.1-1.2-1.51.3-1.1-1.1-1.1-1.3-1.3-1.3-0.6
Cu content in liver1.41.62.11.3-1.31.41.4-1.41.3-1.21.41.41.21.2-1.21.41.41.31.11.11.10.7
Fe content in liver0.40.50.90.8-0.81.00.8-0.70.7-0.60.70.70.70.6-0.60.60.60.70.60.50.50.6
K content in liver0.50.52.6-0.90.9-0.7-0.70.7-0.60.6-0.5-0.5-0.6-0.50.5-0.5-0.5-0.5-0.5-0.4-0.41.6
Mg content in liver0.40.42.7-0.30.4-0.2-0.50.5-0.50.8-0.4-0.4-0.6-0.50.6-0.6-0.6-0.6-0.6-0.6-0.61.6
Mn content in liver0.00.00.10.1-0.10.2-0.10.1-0.10.0-0.1-0.10.0-0.10.1-0.2-0.2-0.2-0.1-0.1-0.2-0.3
Na content in liver0.80.81.80.5-0.50.70.9-0.90.9-0.61.01.00.81.0-0.91.01.01.00.91.01.11.3
Rb content in liver0.81.01.5-0.70.8-0.5-0.91.0-1.01.0-0.9-1.0-1.1-1.21.2-1.0-1.0-1.1-1.2-1.2-1.2-0.1
Se content in liver0.10.10.40.3-0.30.40.3-0.30.3-0.20.30.30.40.4-0.30.20.20.20.30.30.20.7
Sr content in liver0.20.20.40.2-0.00.4-0.10.2-0.20.5-0.3-0.3-0.4-0.50.5-0.4-0.4-0.4-0.5-0.6-0.7-0.3
Zn content in liver0.80.81.4-0.30.5-0.4-0.70.8-0.80.9-1.0-1.0-1.1-1.01.1-1.0-1.0-1.1-1.1-1.1-1.20.5
Bone: minimum diameter0.61.21.6-0.91.0-0.8-1.11.1-1.11.3-1.1-1.1-1.0-1.21.1-1.2-1.2-1.1-1.1-1.1-1.2-0.3
Time in familiar zone, hab. session 10.20.23.3-0.1-0.0-0.2-0.00.00.0-0.50.10.10.3-0.0-0.20.20.20.20.10.10.1-1.8
Time in novel zone, hab. session 10.40.41.30.9-0.91.10.8-0.70.7-0.40.50.50.40.7-0.40.20.20.30.40.40.30.3
Total zone transitions, hab. session 10.30.54.60.9-0.80.90.5-0.50.5-0.30.30.30.50.3-0.20.20.20.20.20.1-0.0-2.2
Total locomotion distance, hab. session 10.60.93.00.00.2-0.0-0.60.7-0.70.9-0.9-0.9-0.7-1.01.0-1.0-1.0-1.1-1.0-1.1-1.3-1.7
Locomotion velocity, hab. session 10.91.32.0-0.60.7-0.7-1.11.1-1.11.3-1.2-1.2-1.1-1.31.3-1.2-1.2-1.3-1.3-1.3-1.4-0.9
Time in familiar zone, hab. session 20.30.30.8-0.90.7-0.8-0.10.10.0-0.40.30.30.60.2-0.50.60.60.50.60.60.80.1
Time in novel zone, hab. session 20.30.31.41.2-1.01.00.6-0.60.5-0.30.20.20.10.4-0.1-0.0-0.00.00.10.1-0.1-0.5
Total zone transitions, hab. session 20.50.61.20.3-0.40.10.7-0.70.8-0.80.70.70.90.9-1.00.80.80.71.11.11.1-1.1
Total locomotion distance, hab. session 20.40.61.0-0.60.7-0.8-0.70.7-0.70.8-0.8-0.8-0.8-0.70.7-0.9-0.9-1.0-0.7-0.6-0.70.1
Locomotion velocity, hab. session 20.60.81.2-0.80.9-0.9-0.80.8-0.81.0-1.0-1.0-1.0-0.80.8-1.0-1.0-1.1-0.8-0.8-0.80.2
Novel to familiar place preference ratio0.60.71.11.0-1.00.80.9-0.90.9-0.80.70.70.70.9-0.80.70.70.70.80.80.7-1.0
Novelty place preference0.50.51.11.1-1.10.80.8-0.80.7-0.60.60.60.50.7-0.60.50.50.60.60.50.4-1.1
Time in novel zone, NPP test0.30.31.40.7-0.70.40.5-0.50.5-0.50.40.40.40.6-0.50.30.30.40.50.40.4-1.2
Total zone transitions, NPP test0.50.78.5-0.90.8-1.1-0.70.7-0.60.2-0.6-0.6-0.1-0.30.2-0.4-0.4-0.4-0.1-0.1-0.1-2.9
Total locomotion distance, NPP test0.50.74.1-0.70.7-0.9-0.70.8-0.70.5-0.8-0.8-0.5-0.70.6-0.8-0.8-0.8-0.5-0.5-0.6-2.0
Locomotion velocity, NPP test0.40.62.6-0.50.5-0.6-0.60.7-0.70.6-0.8-0.8-0.6-0.60.6-0.8-0.8-0.8-0.6-0.6-0.7-1.6
Intraocular pressure0.10.22.20.7-0.70.40.2-0.20.2-0.3-0.0-0.0-0.0-0.00.10.20.2-0.1-0.2-0.2-0.3-1.5
Delta distance traveled before/after self-admin0.20.20.6-0.20.2-0.2-0.30.3-0.30.1-0.4-0.4-0.2-0.20.3-0.8-0.8-0.4-0.3-0.3-0.4-0.8
Delta ambulatory time before/after self-admin1.01.22.5-0.50.7-0.7-1.01.0-1.00.9-1.2-1.2-1.0-1.01.1-1.6-1.6-1.3-1.2-1.2-1.3-0.6
Parametrial fat weight0.10.30.6-0.1-0.10.50.3-0.30.4-0.60.40.40.80.8-0.70.50.50.40.70.80.7-0.6
Pavlov. Cond. lever latency0.70.81.6-0.30.5-0.2-0.80.8-0.91.1-0.8-0.8-0.9-1.21.1-1.0-1.0-0.9-1.2-1.2-1.30.4
Pavlov. Cond. magazine entry latency0.40.51.2-0.0-0.2-0.20.4-0.50.6-1.10.60.60.80.7-0.80.70.70.70.90.91.00.1
Pavlov. Cond. change in total contacts0.20.20.7-0.1-0.1-0.20.3-0.40.4-0.60.40.40.50.7-0.60.50.50.50.70.80.80.1
Pavlov. Cond. index score0.81.02.00.2-0.4-0.00.8-0.80.9-1.30.80.91.11.3-1.21.01.01.01.31.41.4-0.5
Pavlov. Cond. latency score0.60.71.60.2-0.4-0.00.7-0.70.8-1.20.70.70.91.1-1.10.90.90.81.11.21.2-0.5
Pavlov. Cond. lever contacts1.21.52.50.7-0.80.51.1-1.21.2-1.41.11.11.31.6-1.41.31.31.21.51.51.6-0.2
Pavlov. Cond. magazine entry number0.50.71.50.00.20.2-0.60.6-0.71.2-0.7-0.7-1.0-1.01.1-0.8-0.8-0.8-1.1-1.2-1.20.1
Pavlov. Cond. intertrial magazine entries6.17.311.3-3.43.4-3.2-3.13.0-3.02.7-2.8-2.8-2.6-2.62.5-2.5-2.5-2.6-2.4-2.3-2.20.5
Pavlov. Cond. lever-magazine prob. diff.0.70.91.90.2-0.4-0.00.7-0.80.9-1.20.90.91.01.2-1.21.01.01.01.31.31.4-0.3
Pavlov. Cond. response bias1.01.22.8-0.0-0.3-0.20.7-0.80.9-1.40.90.91.31.4-1.41.21.21.11.51.61.7-0.4
Pavlov. Cond. lever latency1.72.34.8-2.22.1-2.0-1.71.6-1.61.4-1.5-1.5-1.5-1.31.3-1.2-1.2-1.2-1.2-1.1-0.91.5
Pavlov. Cond. magazine entry latency3.34.06.42.0-2.11.92.0-2.02.1-2.31.91.92.12.0-2.01.81.81.72.02.01.8-2.5
Pavlov. Cond. change in total contacts3.45.48.22.9-2.82.92.6-2.52.5-2.12.42.42.42.1-2.12.22.22.22.12.01.8-1.6
Pavlov. Cond. index score3.34.56.52.5-2.52.42.3-2.22.2-2.22.12.12.31.9-2.01.91.91.91.91.81.6-2.4
Pavlov. Cond. latency score3.54.76.02.4-2.42.22.3-2.22.3-2.22.22.22.32.0-2.12.02.02.02.12.01.8-2.1
Pavlov. Cond. lever contacts2.23.05.62.4-2.32.22.0-1.91.9-1.71.71.71.81.6-1.51.41.41.41.51.41.1-1.6
Pavlov. Cond. magazine entry number2.83.45.1-2.02.0-1.8-1.91.9-1.91.9-1.8-1.8-2.0-1.91.8-1.7-1.7-1.6-1.8-1.8-1.62.3
Pavlov. Cond. intertrial magazine entries4.46.68.1-2.42.5-2.3-2.62.6-2.62.8-2.7-2.7-2.8-2.62.6-2.6-2.6-2.6-2.6-2.6-2.51.9
Pavlov. Cond. lever-magazine prob. diff.3.95.27.22.7-2.72.62.4-2.42.4-2.32.32.32.42.1-2.12.12.12.12.12.01.8-2.2
Pavlov. Cond. response bias2.33.25.62.4-2.32.22.0-1.91.9-1.81.61.61.81.6-1.61.31.31.41.51.51.2-2.3
Time in closed arm before self-admin4.25.38.83.0-2.92.82.7-2.62.5-2.12.82.82.02.1-1.92.22.22.31.81.71.6-1.1
Time in closed arm after self-admin1.92.17.92.6-2.42.81.8-1.61.5-0.91.51.51.01.0-0.80.90.91.00.60.50.30.3
Time in open arm before self-admin4.44.86.5-2.22.3-2.0-2.42.4-2.32.2-2.4-2.4-2.0-2.32.1-2.6-2.6-2.1-2.0-2.0-1.90.7
Time in open arm after self-admin4.04.411.3-3.43.1-3.1-2.52.4-2.31.6-2.3-2.3-1.7-1.71.5-1.7-1.7-1.8-1.3-1.2-1.0-0.4
Bone: periosteal estimation0.10.10.50.7-0.50.70.2-0.10.10.4-0.1-0.1-0.1-0.20.3-0.3-0.3-0.3-0.3-0.4-0.5-0.2
Bone: periosteal perimeter0.00.00.1-0.00.00.10.2-0.20.2-0.10.20.20.20.3-0.20.20.20.10.20.30.30.1
Bone: post-yield work1.92.83.9-2.01.9-1.9-1.91.9-1.91.7-1.7-1.7-1.4-1.81.6-1.5-1.5-1.5-1.6-1.6-1.50.3
Progressive ratio test 1 active lever presses0.20.30.80.5-0.50.90.6-0.60.5-0.50.30.30.40.7-0.40.30.30.30.40.40.4-0.8
Progressive ratio test 1 breakpoint0.30.41.10.6-0.61.00.7-0.70.6-0.60.40.40.50.8-0.60.40.40.40.60.60.5-1.0
Progressive ratio test 1 inactive lever presses1.62.22.9-1.41.4-1.2-1.51.5-1.61.5-1.7-1.7-1.6-1.31.5-1.7-1.7-1.7-1.5-1.5-1.50.2
Progressive ratio test 2 active lever presses0.10.11.10.7-0.51.00.4-0.40.30.20.10.1-0.10.20.1-0.1-0.1-0.0-0.1-0.2-0.20.4
Progressive ratio test 2 breakpoint0.10.11.00.6-0.51.00.3-0.30.20.3-0.0-0.0-0.20.10.1-0.1-0.1-0.1-0.2-0.2-0.30.3
Progressive ratio test 2 inactive lever presses0.40.61.30.20.00.3-0.40.4-0.50.9-0.7-0.7-1.0-0.81.0-1.0-1.0-0.9-1.0-1.1-1.10.0
Incentive Sensitization - Responses0.10.10.80.6-0.40.90.2-0.20.10.4-0.0-0.0-0.2-0.10.2-0.2-0.2-0.2-0.3-0.3-0.40.7
Incentive Sensitization - Breakpoint0.10.20.70.6-0.40.80.2-0.10.00.5-0.1-0.1-0.3-0.20.3-0.2-0.2-0.3-0.4-0.4-0.50.7
Sum of active levers in priming session hrs 5-60.20.21.3-1.11.0-0.8-0.50.4-0.30.3-0.3-0.3-0.1-0.0-0.1-0.1-0.1-0.10.20.30.40.5
Progressive ratio0.40.74.01.5-1.11.30.5-0.40.30.6-0.0-0.0-0.3-0.60.5-0.5-0.5-0.3-0.6-0.7-0.92.0
Food seeking constrained by brief footshock0.60.71.2-0.10.2-0.7-0.60.6-0.70.8-1.1-1.1-1.1-0.91.0-1.0-1.0-0.8-1.1-1.1-1.1-0.7
Seeking ratio, punishment vs. effort0.40.53.5-1.20.9-1.6-0.70.6-0.6-0.1-0.4-0.4-0.20.10.1-0.0-0.0-0.1-0.00.10.2-1.9
Retroperitoneal fat weight0.10.40.60.5-0.60.20.6-0.60.6-0.70.50.50.70.8-0.70.80.80.40.70.70.7-0.1
Reaction time number correct2.65.07.0-2.62.6-2.4-2.42.4-2.42.5-2.4-2.4-2.3-2.12.2-2.3-2.3-2.0-2.1-2.0-1.90.1
Reaction time mean minus median0.10.23.00.4-0.40.10.1-0.10.1-0.20.00.00.10.2-0.1-0.1-0.1-0.10.10.10.0-1.7
Reaction time mean minus median AUC0.20.47.10.3-0.4-0.20.00.0-0.0-0.1-0.1-0.10.00.10.0-0.2-0.2-0.3-0.0-0.0-0.2-2.7
Reaction time num false alarms1.11.52.4-1.61.6-1.5-1.41.3-1.30.9-1.4-1.4-1.3-1.01.1-1.1-1.1-1.3-1.0-1.0-0.90.3
Reaction time num false alarms AUC1.32.02.7-1.61.6-1.4-1.51.5-1.51.2-1.6-1.6-1.6-1.21.4-1.4-1.4-1.6-1.3-1.2-1.20.7
Reaction time trials correct on left2.65.07.0-2.62.6-2.4-2.42.4-2.42.5-2.4-2.4-2.3-2.12.2-2.3-2.3-2.0-2.1-2.0-1.90.1
Reaction time trials on left2.75.17.0-2.62.6-2.4-2.52.4-2.42.5-2.4-2.4-2.3-2.12.2-2.3-2.3-2.1-2.1-2.0-1.90.0
Reaction time mean0.81.23.91.9-1.81.61.2-1.11.1-0.90.90.90.80.8-0.70.60.60.70.60.50.3-2.0
Reaction time mean AUC0.40.73.61.4-1.41.20.8-0.80.7-0.60.60.60.60.5-0.40.30.30.40.30.20.1-1.9
Median of all reaction times0.60.83.21.8-1.61.61.0-0.90.8-0.60.70.70.60.4-0.40.30.30.50.20.1-0.1-1.5
Reaction time omissions1.01.44.3-0.20.3-0.3-0.91.0-1.10.8-1.3-1.3-1.2-0.91.3-1.4-1.4-1.4-1.2-1.3-1.4-2.1
Reaction time false alarm rate0.10.10.3-0.30.3-0.2-0.30.3-0.3-0.0-0.5-0.5-0.4-0.20.3-0.3-0.3-0.6-0.3-0.3-0.30.5
Reaction time premature initiation rate0.60.82.0-0.40.6-0.7-0.80.9-0.91.4-0.7-0.7-1.0-1.11.1-0.6-0.6-0.8-1.1-1.1-1.1-0.5
Reaction time premature initiations1.93.46.0-1.81.9-1.9-2.02.0-2.02.4-1.8-1.8-2.0-2.01.9-1.6-1.6-1.6-1.9-1.9-1.8-0.4
Std. dev. reaction times0.40.74.81.5-1.41.10.8-0.70.7-0.50.40.40.40.4-0.30.20.20.20.20.1-0.1-2.2
Reaction time trials completed2.75.17.0-2.62.6-2.4-2.52.4-2.42.5-2.4-2.4-2.3-2.12.2-2.3-2.3-2.1-2.1-2.0-1.90.0
Reaction time trials AUC2.85.47.3-2.72.7-2.4-2.52.5-2.52.6-2.4-2.4-2.4-2.22.3-2.4-2.4-2.1-2.2-2.1-2.00.1
Run reversals in cocaine runway, females0.70.71.81.3-1.30.91.0-1.01.0-0.80.90.80.60.7-0.70.30.30.70.70.60.5-0.4
Run reversals in cocaine runway, males0.20.20.40.2-0.10.4-0.20.2-0.30.3-0.1-0.1-0.5-0.50.6-0.5-0.5-0.2-0.6-0.7-0.6-0.3
Latency to leave start box in cocaine runway0.40.51.31.1-1.00.90.9-0.90.8-0.60.40.40.30.7-0.50.50.50.30.50.40.4-1.0
Latency to leave start box in cocaine runway, F0.40.50.80.8-0.80.90.8-0.80.8-0.70.60.60.40.8-0.60.60.60.60.60.60.6-0.5
Latency to leave start box in cocaine runway, M0.20.20.90.7-0.60.40.5-0.50.4-0.10.10.10.10.3-0.20.30.30.00.20.10.1-1.0
Std. dev. time between licks in bursts0.10.11.8-0.20.2-0.3-0.20.2-0.1-0.2-0.2-0.20.30.0-0.1-0.2-0.2-0.20.10.10.0-1.3
Total sessions with >9 infusions0.30.41.81.0-0.91.30.8-0.80.7-0.30.50.50.40.6-0.40.20.20.30.30.30.2-0.4
Short access day 1 total inactive lever presses0.00.10.20.1-0.1-0.0-0.10.1-0.10.3-0.3-0.3-0.2-0.30.3-0.4-0.4-0.2-0.3-0.3-0.30.4
Short access day 10 total inactive lever presses0.10.10.6-0.20.2-0.7-0.40.4-0.40.2-0.4-0.4-0.2-0.30.3-0.2-0.2-0.3-0.3-0.3-0.3-0.8
Short access day 1 total infusions0.10.20.40.3-0.10.5-0.00.1-0.20.6-0.3-0.3-0.5-0.40.5-0.6-0.6-0.4-0.5-0.6-0.60.4
Short access day 10 total infusions0.50.71.30.8-0.81.01.0-1.00.9-0.80.60.60.81.1-0.90.60.60.60.90.90.8-0.8
Short access total infusions0.30.42.31.1-0.91.50.9-0.80.7-0.30.40.40.40.6-0.40.30.30.30.40.30.2-0.4
Short access day 1 locomotion0.40.51.51.2-1.11.20.9-0.90.8-0.40.70.70.50.6-0.50.60.60.50.50.40.3-0.3
Short access day 10 total locomotion1.32.35.50.6-0.90.71.3-1.41.4-1.81.21.21.61.9-1.71.51.51.31.81.91.8-2.3
Short access total locomotion0.40.51.80.6-0.71.00.7-0.70.7-0.60.50.50.50.9-0.60.50.50.50.60.60.6-1.3
One hour access (0.3 mA shock)0.10.10.3-0.60.5-0.6-0.20.2-0.20.1-0.2-0.2-0.10.1-0.10.10.1-0.20.10.20.2-0.4
Compulsive drug intake0.30.41.9-1.41.2-1.3-0.80.8-0.60.2-0.5-0.5-0.1-0.40.2-0.0-0.0-0.2-0.1-0.00.10.1
One hour access (shock baseline)0.00.00.10.2-0.20.00.2-0.20.10.2-0.0-0.0-0.10.10.0-0.1-0.1-0.20.0-0.0-0.0-0.0
Social response proportion0.40.53.70.7-0.51.20.1-0.0-0.10.7-0.0-0.0-0.5-0.50.6-0.2-0.2-0.2-0.8-0.9-0.91.9
Social responses0.10.10.70.7-0.60.90.3-0.30.2-0.00.20.20.10.10.10.30.30.0-0.1-0.2-0.20.2
Social time1.42.04.80.30.10.2-1.01.1-1.21.5-1.3-1.3-1.5-1.71.8-1.5-1.5-1.6-1.9-2.0-2.2-0.1
Soleus weight0.51.47.0-2.72.3-2.3-1.51.4-1.10.3-0.8-0.8-0.2-0.40.1-0.5-0.5-0.50.00.20.3-1.0
Bone: stiffness0.71.21.7-1.31.3-1.1-1.21.2-1.21.2-1.0-1.0-1.0-1.21.1-1.0-1.0-1.0-1.1-1.1-1.00.8
Tibialis anterior weight0.31.13.3-1.81.7-1.8-1.31.2-1.20.7-1.0-1.0-0.8-0.80.7-0.7-0.7-0.9-0.7-0.6-0.4-0.9
Time to tail flick, vehicle, before self-admin0.60.62.4-1.01.0-1.5-0.80.8-0.80.6-0.9-0.9-0.7-0.60.6-0.6-0.6-0.8-0.5-0.5-0.50.3
Time to tail flick, vehicle, after self-admin0.20.20.6-0.10.0-0.10.2-0.30.4-0.30.30.30.50.6-0.60.40.40.50.70.70.80.3
Time to tail flick, test, before self-admin0.20.20.91.0-0.80.80.6-0.50.5-0.40.20.20.10.3-0.10.60.60.30.1-0.0-0.0-0.7
Time to tail flick, test, after self-admin1.01.02.0-1.41.4-1.1-1.21.2-1.11.1-0.8-0.8-0.9-0.90.8-1.1-1.1-1.0-0.8-0.7-0.60.8
Delta time to tail flick, vehicle, before/after SA0.00.00.2-0.40.3-0.1-0.10.0-0.0-0.10.20.20.10.2-0.20.10.10.20.30.30.40.1
Delta time to tail flick, test, before/after SA1.51.52.7-1.61.6-1.4-1.41.4-1.31.3-1.1-1.1-1.0-1.11.0-1.3-1.3-1.3-0.9-0.8-0.80.6
Tibia length0.10.30.7-0.50.5-0.4-0.50.5-0.60.2-0.8-0.8-0.8-0.40.6-0.7-0.7-0.8-0.5-0.5-0.50.1
Ambulatory time before self-admin0.71.01.40.7-0.81.11.0-1.11.0-1.01.01.01.01.1-1.01.21.21.11.11.11.1-0.2
Ambulatory time after self-admin0.10.11.90.2-0.20.40.2-0.20.2-0.4-0.1-0.10.10.3-0.1-0.2-0.2-0.20.10.10.1-1.4
Bone: tissue strength0.00.00.20.4-0.40.10.2-0.20.1-0.3-0.2-0.2-0.20.20.1-0.1-0.1-0.1-0.1-0.1-0.10.3
Total heroin consumption1.92.36.9-2.62.5-2.4-1.81.7-1.61.4-1.6-1.6-1.3-1.21.0-1.0-1.0-1.2-0.9-0.8-0.50.5
Bone: trabecular number0.30.52.9-0.70.6-1.1-0.60.6-0.60.3-0.7-0.7-0.4-0.20.4-0.7-0.7-0.5-0.3-0.3-0.3-1.7
Bone: trabecular spacing0.10.11.00.4-0.40.70.3-0.30.3-0.30.30.30.20.0-0.20.30.30.20.20.20.21.0
Bone: trabecular thickness0.00.00.50.1-0.1-0.10.1-0.10.1-0.10.00.00.10.3-0.20.10.10.10.20.20.2-0.7
Bone: trabecular tissue density0.10.22.00.1-0.10.30.4-0.40.30.10.30.30.10.4-0.30.40.40.40.30.30.41.4
Water consumed over 24 hours1.72.33.2-1.21.4-1.1-1.41.4-1.51.7-1.6-1.6-1.8-1.51.7-1.7-1.7-1.7-1.6-1.6-1.60.8
Number of responses in last shaping day0.00.00.40.2-0.20.30.1-0.10.1-0.00.10.10.20.1-0.1-0.0-0.0-0.10.00.0-0.1-0.7