Il1rl1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Il1rl1 0.07 0.04 3.8e-05 0.04 0.06 0.04 0.05 1.5e-04 2.4e-05 2.7e-04 6.4e-05
2 Adipose isoform ratio NM_001127689.1 0.09 0.05 1.8e-09 0.05 0.06 0.07 0.06 1.4e-06 1.6e-07 2.5e-08 6.0e-07
3 Adipose alternative TSS NM_013037.1 0.13 0.06 2.2e-16 0.13 0.12 0.11 0.12 2.1e-14 2.7e-13 1.2e-12 7.6e-13
4 Adipose alternative TSS XM_039083073.2 0.08 0.05 4.9e-05 0.03 0.03 0.07 0.03 1.4e-04 2.0e-04 8.8e-08 1.5e-04
5 Adipose alternative TSS XM_039083073.2 0.09 0.05 2.5e-07 0.06 0.05 0.06 0.04 9.6e-07 3.4e-06 1.0e-07 1.1e-05
6 Adipose alternative TSS XM_006244739.5 0.04 0.03 1.6e-04 0.01 0.02 0.01 0.02 2.3e-02 4.0e-03 3.5e-02 4.7e-03
7 Adipose isoform ratio NM_013037.1 0.02 0.02 7.1e-03 0.01 0.01 0.01 0.01 1.2e-02 6.7e-02 4.2e-02 6.8e-02
8 Adipose alternative polyA NM_013037.1 0.03 0.02 2.7e-03 0 0.01 0 0 1.5e-01 3.6e-02 1.1e-01 2.0e-01
9 Adipose alternative TSS XM_006244739.5 0.04 0.03 1.2e-04 0.04 0.03 0.03 0.03 5.1e-05 5.8e-04 4.8e-04 1.0e-04
10 BLA gene expression Il1rl1 0.09 0.06 2.3e-04 0.1 0.07 0.05 0.07 5.4e-06 1.3e-04 8.8e-04 1.0e-04
11 PL gene expression Il1rl1 0.04 0.03 1.6e-04 0.03 0.03 0.02 0.02 1.9e-04 7.6e-04 2.5e-03 1.7e-03
12 NAcc gene expression Il1rl1 0.06 0.03 4.0e-08 0.06 0.05 0.06 0.06 2.7e-09 1.8e-08 6.2e-09 4.3e-09
13 Adipose alternative polyA NM_001127689.1 0.15 0.07 5.6e-17 0.09 0.12 0.12 0.07 1.4e-10 2.6e-13 3.7e-13 1.0e-08
14 Adipose alternative TSS XM_017596290.3 0.52 0.11 0.0e+00 0.39 0.46 0.49 0.38 4.8e-46 2.4e-56 1.6e-62 8.3e-45
15 Adipose isoform ratio XM_017596290.3 0.57 0.12 0.0e+00 0.45 0.45 0.5 0.36 3.8e-55 7.4e-56 6.1e-64 1.7e-41
16 Adipose alternative TSS XM_017596290.3 0.51 0.11 0.0e+00 0.45 0.45 0.5 0.35 2.4e-55 2.0e-55 4.0e-63 9.7e-41
17 Adipose mRNA stability Il1rl1 0.43 0.12 0.0e+00 0.35 0.35 0.38 0.31 3.5e-40 9.0e-41 3.6e-44 1.8e-34
18 Adipose alternative polyA XM_039083070.2 0.11 0.06 6.0e-10 0.04 0.06 0.05 0.03 1.9e-05 1.6e-07 1.1e-06 1.2e-04
19 Adipose alternative TSS NM_001127689.1 0.11 0.06 5.7e-12 0.08 0.09 0.09 0.06 1.2e-09 5.9e-10 1.1e-09 3.6e-07
20 Adipose alternative polyA NM_001127689.1 0.13 0.07 5.8e-13 0.06 0.09 0.08 0.04 6.2e-07 7.4e-10 3.2e-09 1.5e-05
21 Adipose alternative polyA XM_039083070.2 0.13 0.07 6.6e-13 0.06 0.09 0.08 0.04 6.6e-07 7.5e-10 4.3e-09 2.0e-05
22 Liver gene expression Il1rl1 0.03 0.02 7.2e-03 0 0.01 0.01 0.01 1.7e-01 4.1e-02 2.7e-02 1.7e-02
23 Adipose isoform ratio XM_039083072.2 0.23 0.09 0.0e+00 0.18 0.2 0.2 0.18 5.3e-20 3.2e-21 2.6e-21 7.6e-20
24 Adipose intron excision ratio chr9_50192860_50204467 0.31 0.18 7.3e-13 0.09 0.08 0.08 0.09 6.5e-10 6.9e-09 6.3e-09 1.1e-09
25 Adipose isoform ratio XM_039083070.2 0.04 0.03 1.3e-04 0.03 0.03 0.02 0.02 3.9e-04 7.4e-04 2.0e-03 9.7e-04
26 Adipose intron excision ratio chr9_50172459_50204467 0.05 0.03 3.4e-05 0.03 0.03 0.02 0.03 2.1e-04 1.2e-04 3.7e-03 2.0e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density2.03.77.2-1.7-2.72.31.10.40.11.6-2.50.1-0.10.10.12.4-2.4-2.4-2.42.3-2.4-2.42.4-2.42.42.31.7-1.7-1.7
Area under the delay curve0.71.14.00.51.3-1.10.80.70.1-0.11.0-0.30.10.70.5-1.21.11.21.1-1.21.30.9-1.21.2-1.1-1.3-1.22.01.2
BMI with tail1.24.17.32.12.4-2.3-1.80.1-0.4-2.42.50.80.1-0.9-0.6-2.42.72.72.6-2.52.32.5-2.32.3-2.3-2.3-2.11.41.5
BMI without tail0.10.52.31.10.4-0.8-1.0-0.2-1.1-0.50.51.5-0.9-1.2-1.0-0.30.40.30.3-0.20.20.3-0.20.2-0.1-0.20.3-0.5-0.5
Body weight0.21.03.4-1.7-0.81.31.0-0.41.81.3-0.9-1.61.81.61.70.6-0.5-0.4-0.50.6-0.5-0.60.5-0.5-0.20.3-0.30.40.7
Weight adjusted by age0.31.02.3-0.30.7-0.51.00.91.1-0.10.8-1.21.11.11.0-0.90.91.00.9-1.01.01.0-1.01.1-1.1-1.1-1.21.51.4
Bone surface1.52.97.5-2.7-2.12.52.30.52.11.9-2.1-1.71.72.02.11.7-1.6-1.5-1.51.5-1.5-1.61.5-1.50.81.30.3-0.20.2
Bone volume1.73.57.0-2.3-2.62.52.00.61.11.9-2.4-0.80.71.11.12.2-2.2-2.2-2.22.1-2.1-2.22.1-2.11.82.01.2-1.1-0.9
Breakpoint value in progressive ratio session1.52.64.9-2.0-1.71.81.0-0.30.62.1-1.8-0.90.10.90.91.8-2.2-2.1-2.21.8-1.7-1.81.7-1.72.01.91.9-1.3-1.0
Number of licking bursts0.51.62.8-0.6-1.61.20.40.1-0.51.2-1.40.3-0.5-0.3-0.31.5-1.6-1.5-1.61.7-1.5-1.61.6-1.61.71.51.6-1.4-1.4
Context. condit. distance diff. score3.03.612.82.80.2-1.3-2.2-0.1-3.6-0.90.43.5-3.5-3.5-3.50.1-0.3-0.5-0.30.5-0.4-0.30.4-0.51.20.71.7-2.1-2.5
Locomotion velocity, session 10.40.41.60.8-0.0-0.5-0.40.0-1.20.10.21.2-1.2-1.0-1.10.0-0.4-0.4-0.40.2-0.1-0.10.1-0.10.90.30.7-0.9-0.9
Locomotion distance, session 10.50.61.61.20.8-1.3-0.60.5-1.1-0.71.01.3-1.1-0.8-0.9-0.80.50.40.5-0.60.80.8-0.70.7-0.0-0.5-0.00.0-0.2
Locomotion velocity, session 20.20.30.80.00.7-0.60.00.10.3-0.30.7-0.0-0.00.50.5-0.70.40.50.5-0.50.80.8-0.70.7-0.4-0.7-0.50.90.6
Locomotion distance, session 20.30.41.1-0.40.3-0.30.70.90.8-0.10.6-0.50.80.90.8-0.60.40.40.4-0.50.70.7-0.70.7-0.5-0.6-0.91.00.9
Locomotion velocity, session 30.30.30.6-0.1-0.60.40.40.3-0.40.8-0.50.3-0.6-0.3-0.40.6-0.7-0.7-0.70.8-0.6-0.60.6-0.60.70.70.7-0.7-0.8
Locomotion distance, session 30.30.31.40.4-0.2-0.20.20.8-1.00.20.00.8-1.2-0.8-0.80.3-0.5-0.5-0.50.5-0.2-0.30.3-0.30.80.50.8-0.1-0.8
Stereotopy head waving bouts, day 30.20.30.7-0.8-0.60.80.6-0.10.70.6-0.7-0.70.70.70.70.5-0.4-0.4-0.40.3-0.5-0.40.4-0.40.10.40.1-0.20.1
Stereotopy head waving duration, day 30.70.91.8-1.0-1.31.30.90.30.61.0-1.2-0.60.50.50.51.1-1.1-1.1-1.01.1-1.1-1.01.1-1.10.71.00.8-0.7-0.5
Locomotion velocity, session 70.40.41.5-1.1-0.40.90.9-0.10.80.6-0.6-0.60.11.11.20.5-0.6-0.6-0.60.8-0.3-0.50.4-0.40.10.40.50.20.2
Locomotion distance, session 70.91.22.0-1.2-1.21.30.6-0.40.41.2-1.4-0.40.00.60.71.3-1.4-1.4-1.41.4-1.2-1.41.2-1.21.01.21.1-0.8-0.7
Stereotopy head waving bouts, day 70.10.20.80.40.3-0.3-0.8-0.9-0.1-0.20.30.0-0.10.10.1-0.30.40.50.4-0.10.30.2-0.30.3-0.5-0.4-0.30.60.3
Stereotopy head waving duration, day 70.20.20.40.50.4-0.5-0.7-0.4-0.1-0.40.50.1-0.1-0.0-0.1-0.50.50.50.6-0.20.50.4-0.40.4-0.6-0.5-0.50.60.3
Locomotion velocity, session 81.31.55.91.70.2-1.1-1.30.7-2.3-1.10.62.2-2.4-2.1-2.2-0.1-0.2-0.4-0.30.3-0.00.10.1-0.11.10.31.1-1.2-1.5
Locomotion distance, session 80.91.35.91.70.2-1.0-0.80.8-2.1-0.30.52.4-2.2-2.1-2.1-0.1-0.2-0.3-0.20.3-0.00.10.1-0.10.80.30.9-1.2-1.4
Degree of sensitization distance0.30.43.2-0.7-0.00.6-0.6-1.80.90.2-0.5-0.80.91.01.00.20.10.00.10.0-0.2-0.30.2-0.2-0.6-0.0-0.1-0.20.5
Degree of sensitization stereotypy0.70.71.30.80.9-0.9-1.2-1.0-0.1-0.60.90.00.1-0.0-0.0-0.91.11.11.1-0.70.90.8-0.90.9-1.1-1.0-0.91.10.7
Conditioned locomotion0.10.21.0-0.2-0.10.30.50.50.60.5-0.1-0.81.00.30.3-0.10.30.40.2-0.20.00.1-0.10.1-0.5-0.2-0.30.10.5
Cocaine response after cond. corrected0.10.11.4-0.0-0.10.2-1.0-1.2-0.0-0.4-0.1-0.10.10.00.00.1-0.1-0.1-0.10.3-0.2-0.20.2-0.20.10.10.2-0.2-0.1
Cocaine response after cond. not corrected0.20.30.7-0.8-0.50.80.1-0.50.70.4-0.6-0.70.60.70.80.5-0.5-0.5-0.50.6-0.4-0.50.4-0.40.20.30.1-0.00.1
Cocaine response before conditioning0.80.93.9-1.6-0.61.02.01.01.31.4-0.8-1.30.91.41.40.6-0.8-0.7-0.70.5-0.4-0.50.5-0.50.30.5-0.20.40.3
Saline control response0.30.41.00.91.0-1.0-0.70.2-0.5-0.90.80.6-0.6-0.5-0.4-0.80.70.60.7-0.80.70.6-0.70.7-0.5-0.7-0.30.50.3
Bone: connectivity density0.40.61.6-1.3-0.91.20.5-0.40.90.6-1.1-0.50.80.90.90.8-0.7-0.7-0.70.6-0.8-0.90.7-0.70.40.70.1-0.20.0
Bone: cortical apparent density0.20.41.00.40.6-0.7-0.31.0-0.0-0.80.90.50.1-0.1-0.1-0.70.50.50.5-0.60.80.9-0.80.8-0.3-0.7-0.70.70.4
Bone: cortical area1.22.05.6-2.4-1.52.01.3-0.62.31.2-1.4-2.22.32.12.11.1-0.9-0.8-0.81.0-0.9-1.00.9-0.9-0.20.6-0.30.40.7
Bone: cortical porosity1.51.73.8-1.8-1.61.92.00.41.21.8-1.6-1.30.81.11.11.4-1.2-1.2-1.21.2-1.3-1.31.3-1.30.81.20.8-0.8-0.3
Bone: cortical porosity2.02.34.8-1.9-2.02.21.80.21.22.0-2.0-1.31.01.01.01.7-1.5-1.4-1.51.5-1.7-1.61.6-1.61.01.50.9-1.1-0.5
Bone: cortical thickness0.20.31.2-0.8-0.60.80.1-0.70.90.3-0.6-0.71.10.80.70.5-0.2-0.2-0.20.3-0.4-0.40.4-0.4-0.30.2-0.30.20.3
Bone: cortical thickness1.41.72.9-1.7-1.71.61.60.60.71.6-1.6-0.80.81.00.91.5-1.6-1.5-1.61.4-1.4-1.51.4-1.41.61.30.5-0.4-0.6
Bone: cortical tissue density0.20.31.40.40.5-0.7-0.21.2-0.1-0.70.80.60.1-0.1-0.1-0.70.40.40.4-0.50.70.8-0.70.7-0.1-0.5-0.60.60.3
Condit. Reinf. active minus inactive responses0.50.67.20.70.3-0.3-2.2-2.7-0.7-0.30.00.7-0.6-0.6-0.70.10.20.10.20.1-0.1-0.30.2-0.2-0.20.00.2-0.3-0.4
Condit. Reinf. active-inactive response ratio1.61.810.61.91.1-1.3-3.3-3.1-1.7-1.30.71.4-1.7-1.5-1.6-0.60.90.70.8-0.40.50.2-0.40.4-0.6-0.50.2-0.1-0.5
Condit. Reinf. active responses0.40.55.2-0.5-0.50.6-1.3-2.30.20.1-0.7-0.20.40.30.20.6-0.5-0.5-0.50.6-0.6-0.80.6-0.60.30.50.3-0.3-0.2
Condit. Reinf. inactive responses0.81.03.7-1.9-0.61.21.10.11.90.7-0.7-1.61.91.81.80.5-0.6-0.5-0.50.3-0.3-0.30.3-0.30.10.3-0.50.40.8
Incentive salience index mean0.70.95.30.5-0.30.0-2.2-2.3-1.1-0.5-0.41.1-1.0-0.9-1.10.6-0.5-0.7-0.60.7-0.6-0.70.7-0.70.80.70.9-1.0-1.1
Condit. Reinf. lever presses0.81.22.40.3-0.70.3-1.5-1.1-1.2-0.8-0.61.3-1.3-1.1-1.20.8-1.1-1.3-1.11.0-0.9-0.80.9-0.91.41.11.4-1.3-1.5
Condit. Reinf. active minus inactive responses1.01.53.4-1.8-1.31.90.2-1.41.61.5-1.5-1.61.81.21.31.3-0.9-0.8-0.81.2-1.2-1.31.2-1.1-0.00.90.1-0.20.3
Condit. Reinf. active-inactive response ratio1.11.73.2-1.3-1.81.80.1-0.90.51.4-1.7-0.20.30.20.31.7-1.5-1.5-1.51.6-1.7-1.71.7-1.71.11.51.4-1.1-0.9
Condit. Reinf. active responses0.60.83.1-1.4-0.61.2-0.3-1.31.60.6-0.8-1.61.81.21.20.6-0.3-0.3-0.20.6-0.5-0.60.5-0.5-0.50.2-0.50.30.7
Condit. Reinf. inactive responses0.30.51.1-0.50.6-0.1-0.2-0.21.0-0.60.4-1.01.01.00.9-0.50.40.50.5-0.40.60.6-0.60.6-0.8-0.6-1.01.01.0
Condit. Reinf. lever presses0.71.02.0-1.1-1.41.30.71.20.60.6-1.2-0.20.40.20.21.2-1.3-1.3-1.21.2-1.2-1.11.1-1.10.91.00.7-0.4-0.5
Condit. Reinf. lever reinforcers received0.50.73.0-1.3-0.61.2-0.3-1.01.50.5-0.8-1.51.71.21.10.6-0.4-0.4-0.30.6-0.5-0.60.5-0.5-0.50.2-0.50.40.7
Conditioned reinforcement - actives0.20.97.8-1.3-0.21.0-0.6-2.80.81.0-0.9-1.00.41.11.10.8-0.6-0.6-0.60.6-0.7-0.90.7-0.70.30.70.4-0.60.0
Conditioned reinforcement - inactives0.30.92.3-0.31.3-0.4-0.9-1.50.9-0.70.8-0.60.31.11.1-0.80.80.80.8-0.81.00.9-1.01.0-1.3-1.0-0.61.31.2
Conditioned locomotion0.40.64.6-1.20.50.6-0.3-2.11.20.8-0.2-1.21.11.41.40.10.00.10.0-0.20.0-0.20.0-0.0-0.40.0-0.6-0.00.7
Patch foraging indifference point 0 sec0.20.52.40.30.9-0.5-1.4-1.60.2-1.10.6-0.00.40.10.3-0.70.80.70.8-0.70.70.6-0.70.7-0.9-0.7-0.60.60.7
Patch foraging indifference point AUC0.10.20.7-0.50.00.60.80.40.80.7-0.1-0.70.80.80.7-0.00.30.40.30.00.10.1-0.10.1-0.6-0.1-0.90.30.6
Delay disc. indifference point, 0s delay0.70.84.30.31.0-0.91.62.10.00.20.9-0.3-0.10.40.5-0.90.60.80.7-0.81.00.8-0.90.9-0.5-0.9-0.71.70.7
Delay disc. indifference point, 16s delay0.10.10.70.60.2-0.5-0.00.2-0.80.30.10.4-0.3-0.4-0.2-0.10.10.10.1-0.20.1-0.2-0.00.00.3-0.1-0.2-0.0-0.2
Delay disc. indifference point, 2s delay0.50.62.3-0.40.7-0.20.90.40.90.50.4-1.00.91.10.8-0.50.60.70.6-0.50.60.4-0.60.6-0.9-0.8-0.81.51.1
Delay disc. indifference point, 24s delay0.10.10.70.40.4-0.60.50.5-0.50.10.20.4-0.8-0.1-0.1-0.30.30.30.3-0.50.30.1-0.30.30.1-0.2-0.20.00.0
Delay disc. indifference point, 4s delay1.21.35.00.31.4-1.00.10.10.5-0.41.2-0.40.50.80.6-1.31.21.31.2-1.21.41.1-1.31.3-1.5-1.5-1.32.21.4
Delay disc. indifference point, 8s delay0.61.03.20.51.3-1.10.90.90.0-0.21.1-0.2-0.20.60.3-1.21.11.11.0-1.21.31.0-1.21.2-0.9-1.3-1.01.81.1
Indifference point function ln k0.30.92.01.11.3-1.4-0.80.0-0.7-1.11.20.8-0.8-0.5-0.4-1.10.90.90.9-1.11.11.1-1.11.1-0.7-1.0-0.20.50.4
Indifference point function log k0.30.92.01.11.3-1.4-0.80.0-0.7-1.11.20.8-0.8-0.5-0.4-1.10.90.90.9-1.11.11.1-1.11.1-0.7-1.0-0.20.50.4
Patch foraging total patch changes 0 sec0.20.52.40.20.9-0.4-1.3-1.60.4-0.90.6-0.20.60.20.4-0.60.70.60.7-0.60.60.6-0.60.6-0.9-0.7-0.70.70.8
Patch foraging total patch changes 12 sec0.30.41.9-0.1-0.60.61.01.4-0.21.0-0.50.6-0.1-0.5-0.50.6-0.5-0.4-0.40.6-0.7-0.40.6-0.60.40.70.3-0.8-0.7
Patch foraging total patch changes 18 sec0.20.61.5-0.30.80.3-0.2-0.80.9-0.20.3-1.10.90.91.0-0.50.80.90.8-0.40.60.5-0.60.6-1.1-0.6-1.20.81.1
Patch foraging total patch changes 24 sec0.20.72.2-1.4-0.31.20.9-0.41.51.1-0.7-1.41.31.41.40.5-0.3-0.2-0.20.5-0.4-0.50.4-0.4-0.40.3-0.40.30.6
Patch foraging total patch changes 6 sec0.20.30.90.10.6-0.1-0.1-0.20.5-0.40.4-0.30.40.30.3-0.50.70.70.7-0.40.50.5-0.50.5-1.0-0.6-0.80.60.7
Patch foraging time to switch 0 sec0.10.65.5-0.1-0.60.41.62.3-0.20.6-0.50.3-0.4-0.4-0.50.5-0.6-0.6-0.60.4-0.6-0.40.5-0.50.60.60.8-0.5-0.6
Patch foraging water rate 0 sec0.10.45.20.40.5-0.5-1.9-2.3-0.4-0.60.20.5-0.2-0.3-0.1-0.10.30.20.30.00.2-0.1-0.10.1-0.3-0.3-0.40.30.0
Patch foraging water rate 12 sec0.31.36.20.41.4-0.9-2.0-2.50.3-1.60.9-0.20.30.50.6-1.01.00.91.0-0.91.10.9-1.11.0-1.2-1.2-1.01.31.1
Patch foraging water rate 18 sec0.51.25.01.11.4-1.6-2.2-2.0-0.8-1.61.11.0-1.0-0.7-0.7-1.00.90.80.9-1.01.00.9-0.90.9-0.8-1.0-0.10.30.2
Patch foraging water rate 24 sec0.10.10.7-0.1-0.10.2-0.8-0.8-0.1-0.4-0.20.4-0.5-0.1-0.00.3-0.4-0.5-0.30.5-0.2-0.30.2-0.2-0.00.10.50.1-0.2
Patch foraging water rate 6 sec0.10.10.8-0.20.40.1-0.8-0.90.3-0.90.20.2-0.10.30.3-0.1-0.0-0.20.00.20.30.2-0.20.2-0.3-0.2-0.10.60.3
Seeking ratio, delayed vs. immediate footshock1.11.63.1-0.8-1.81.3-0.1-0.4-0.21.0-1.50.0-0.1-0.3-0.41.6-1.6-1.6-1.51.6-1.7-1.61.7-1.71.51.51.1-1.3-1.3
Distance traveled before self-admin0.91.93.7-1.2-1.91.50.80.20.21.2-1.70.1-0.00.30.21.7-1.8-1.8-1.81.6-1.7-1.61.6-1.61.71.61.7-1.3-1.1
Distance traveled after self-admin0.91.52.7-1.0-1.61.40.80.1-0.11.3-1.40.6-0.30.1-0.01.4-1.6-1.6-1.61.5-1.4-1.41.4-1.41.61.51.4-1.0-1.1
Extensor digitorum longus weight4.116.428.90.94.7-3.20.41.62.6-2.44.2-2.62.82.62.7-4.64.64.84.7-4.64.84.7-4.84.8-5.4-4.9-5.05.15.1
Bone: elastic displacement0.00.00.20.1-0.10.2-0.00.2-0.10.0-0.10.4-0.2-0.2-0.20.10.10.10.00.1-0.1-0.10.1-0.1-0.10.00.3-0.3-0.1
Bone: elastic work1.01.33.1-1.4-1.71.81.30.01.01.6-1.5-0.40.90.80.71.3-1.0-0.9-1.01.1-1.3-1.31.3-1.30.61.10.8-0.8-0.3
Bone: endosteal estimation1.74.19.7-3.1-2.63.02.30.02.42.4-2.4-2.22.02.22.22.1-2.1-2.0-2.02.1-1.9-1.91.9-1.91.01.70.7-0.4-0.0
Bone: endosteal perimeter0.71.64.8-2.2-1.41.91.4-0.32.01.2-1.3-2.01.81.91.91.1-0.9-0.8-0.81.1-0.9-0.90.9-0.80.10.7-0.10.40.6
Epididymis fat weight0.42.27.3-2.5-0.71.81.8-1.32.62.0-1.2-2.72.12.62.70.8-0.5-0.3-0.40.6-0.5-0.80.6-0.5-0.50.3-0.50.71.2
Delta time in closed arm before/after self-admin0.90.92.21.50.9-1.2-0.50.6-0.9-0.81.21.2-1.1-1.0-1.1-1.01.00.90.9-0.71.01.1-0.90.9-0.8-1.0-0.20.50.1
Delta time in open arm before/after self-admin0.20.20.4-0.3-0.60.40.20.20.00.3-0.50.3-0.10.10.20.5-0.6-0.6-0.60.5-0.5-0.60.5-0.50.50.50.6-0.0-0.3
Diff in mean of infusions in LGA sessions0.50.91.7-1.1-1.21.30.4-0.40.50.7-1.2-0.60.30.40.21.2-1.2-1.2-1.21.2-1.2-1.01.1-1.11.11.21.2-0.7-0.7
Delay discount exponential model param0.60.83.3-0.3-1.10.9-0.6-0.4-0.2-0.0-0.80.3-0.1-0.8-0.51.0-1.0-1.0-1.01.0-1.1-0.71.0-1.00.91.21.0-1.8-1.1
Extinction: sum of active levers before priming0.91.34.1-0.8-1.31.20.90.4-0.12.0-1.4-0.40.4-0.3-0.21.3-1.2-1.1-1.21.2-1.4-1.41.4-1.41.21.41.0-1.6-1.0
Active lever presses in extinction session 61.91.96.4-2.3-0.51.51.5-0.92.52.1-0.9-2.52.42.42.40.5-0.4-0.2-0.40.2-0.3-0.50.3-0.3-0.40.2-0.40.91.3
Bone: final force2.03.38.9-3.0-2.12.72.1-0.32.62.3-2.1-2.42.72.42.31.7-1.4-1.3-1.31.4-1.5-1.61.5-1.50.31.2-0.1-0.10.5
Bone: final moment1.62.67.1-2.7-1.82.41.8-0.32.42.0-1.8-2.22.52.22.11.5-1.2-1.1-1.11.2-1.3-1.31.3-1.20.21.0-0.20.00.5
Food consumed during 24 hour testing period0.10.10.4-0.7-0.00.40.1-0.30.50.4-0.3-0.20.30.50.50.3-0.3-0.3-0.30.2-0.2-0.30.2-0.2-0.00.20.20.10.1
Glucose0.10.10.30.40.5-0.4-0.5-0.3-0.5-0.40.20.5-0.5-0.3-0.3-0.20.20.10.2-0.30.20.1-0.20.10.1-0.1-0.40.1-0.1
Heart weight1.93.111.0-3.0-0.92.12.80.23.22.0-1.2-2.82.73.33.30.8-0.6-0.4-0.50.6-0.4-0.60.4-0.4-0.70.2-0.61.21.6
Delay discount hyperbolic model param0.81.13.9-0.4-1.31.1-0.5-0.3-0.20.1-1.00.4-0.2-0.8-0.51.2-1.1-1.2-1.11.2-1.3-0.91.2-1.21.11.31.2-2.0-1.2
Intermittent access intake day 1-15 change0.20.92.40.1-0.50.4-0.5-0.8-1.00.8-0.80.9-1.4-0.7-0.80.9-0.9-1.0-1.00.9-0.9-1.01.0-1.01.01.01.5-1.2-1.2
Intermittent access intake escalation0.10.41.90.4-0.00.0-0.7-0.9-0.90.4-0.30.9-1.4-0.6-0.70.4-0.4-0.4-0.40.4-0.5-0.60.5-0.50.40.51.1-0.8-0.9
Intermittent access intake escalation 20.81.33.8-0.3-0.90.7-0.1-0.4-0.81.0-1.10.8-1.5-0.5-0.61.2-1.4-1.5-1.41.4-1.2-1.31.2-1.31.41.32.0-1.3-1.4
Intermitt. access day 1 inactive lever presses0.00.41.70.5-0.3-0.0-0.40.1-0.8-0.3-0.11.3-1.0-0.8-0.80.2-0.4-0.5-0.40.2-0.3-0.10.3-0.30.60.51.0-1.0-0.8
Intermitt. access day 15 inactive lever presses0.20.82.60.31.2-0.6-1.1-1.60.3-1.30.90.00.10.50.5-1.01.11.01.1-0.91.01.0-1.01.0-1.2-1.0-0.70.60.9
Intermitt. access escalation Index0.10.20.8-0.6-0.30.4-0.5-0.90.20.2-0.3-0.2-0.00.20.30.4-0.7-0.8-0.70.6-0.3-0.50.4-0.40.80.40.20.3-0.2
Intermittent access day 1 total infusions0.20.710.1-0.6-0.30.6-1.9-3.20.40.3-0.5-0.70.90.30.30.6-0.4-0.4-0.40.6-0.5-0.60.6-0.60.10.40.1-0.3-0.1
Intermittent access day 15 total infusions0.20.68.90.20.30.1-2.0-3.0-0.40.0-0.20.3-0.4-0.2-0.30.3-0.1-0.1-0.10.2-0.3-0.50.4-0.40.10.30.4-0.6-0.4
Intermittent access terminal intake (last 3 days)0.30.56.6-0.6-0.20.6-1.2-2.60.20.7-0.6-0.30.10.30.20.6-0.5-0.5-0.50.6-0.6-0.70.6-0.60.20.50.5-0.5-0.3
Intermittent access total infusions0.40.56.1-0.6-0.20.7-1.1-2.50.40.7-0.6-0.50.60.40.30.6-0.4-0.4-0.40.5-0.6-0.70.6-0.60.10.50.3-0.6-0.2
Intermittent access day 1 locomotion0.20.41.9-0.80.00.4-0.3-1.41.00.6-0.1-0.91.11.01.00.1-0.00.00.00.10.1-0.0-0.00.0-0.4-0.1-0.50.60.7
Intermittent access day 15 total locomotion0.10.45.2-0.50.70.1-1.0-2.30.6-0.30.1-0.90.61.00.9-0.20.20.20.2-0.40.30.1-0.30.3-0.3-0.2-0.30.20.6
Intermittent access total locomotion0.30.31.20.20.8-0.4-0.8-1.10.2-0.30.5-0.10.40.30.3-0.50.60.60.6-0.50.50.5-0.50.5-0.8-0.6-0.60.50.5
Intermittent access standard deviation0.21.03.70.7-0.30.1-1.3-1.5-1.30.0-0.51.5-1.4-1.0-1.20.6-0.5-0.6-0.60.5-0.7-0.70.7-0.70.80.81.5-1.9-1.3
Left kidney weight0.43.67.1-2.7-2.62.72.60.41.82.7-2.3-1.71.51.71.72.0-2.0-1.8-1.92.0-1.8-1.91.8-1.81.51.71.2-0.8-0.3
Right kidney weight0.64.08.4-2.7-2.62.62.80.81.72.9-2.2-1.81.31.41.52.2-2.2-2.1-2.22.3-1.9-1.92.0-1.91.61.91.2-0.9-0.6
Cocaine induced anxiety0.10.44.80.40.1-0.31.12.20.1-0.50.40.30.1-0.1-0.1-0.40.50.50.5-0.40.40.6-0.50.5-0.5-0.5-0.40.20.3
Post-drug Anxiety1.61.83.01.41.2-1.5-0.01.6-0.2-1.41.60.50.0-0.5-0.6-1.61.71.71.7-1.51.51.7-1.51.5-1.5-1.6-1.71.11.0
Baseline Anxiety1.01.64.91.21.4-1.3-2.2-2.0-0.3-1.31.30.10.1-0.5-0.5-1.31.51.51.6-1.41.21.1-1.21.2-1.4-1.3-1.80.80.8
Tail length1.05.411.1-3.0-2.93.21.9-0.81.73.3-2.9-1.61.61.81.72.7-2.6-2.6-2.62.7-2.5-2.82.6-2.61.72.31.7-1.4-0.8
Length with tail2.511.025.8-5.1-3.84.73.7-0.43.74.7-3.9-3.73.33.83.63.5-3.4-3.2-3.23.4-3.0-3.33.1-3.01.62.71.4-0.6-0.0
Length without tail1.05.418.1-4.0-1.52.92.6-0.54.12.8-1.8-4.33.83.93.81.3-1.2-0.9-1.01.2-0.9-1.10.9-0.9-0.50.6-0.81.51.8
Times rat made contact with spout1.82.13.6-0.5-1.71.20.40.6-0.81.1-1.50.8-0.7-0.8-0.81.7-1.7-1.8-1.81.7-1.7-1.71.7-1.71.91.81.8-1.7-1.8
Lifetime Intake0.40.57.6-0.40.00.4-1.6-2.70.20.3-0.3-0.30.50.20.20.4-0.2-0.2-0.20.3-0.4-0.50.4-0.4-0.00.30.1-0.3-0.1
Liver weight, left4.07.018.7-4.3-2.83.74.21.03.93.7-2.7-3.33.23.83.82.2-2.0-1.7-1.92.0-1.8-1.91.8-1.80.51.50.40.41.0
Liver weight, right0.50.92.2-1.2-1.41.40.7-0.30.81.5-1.2-0.10.50.50.61.1-1.0-1.0-1.01.2-1.1-1.11.1-1.10.60.90.9-0.6-0.3
Locomotor activity0.30.40.7-0.8-0.60.90.6-0.10.30.8-0.80.40.30.40.60.7-0.8-0.8-0.80.8-0.7-0.70.7-0.70.60.70.8-0.7-0.3
Locomotor testing distance0.30.81.8-0.0-0.80.60.40.9-0.80.2-0.71.2-0.5-0.7-0.50.8-1.0-1.1-1.01.0-0.9-0.80.8-0.91.31.01.0-1.1-1.1
Locomotor testing rearing0.41.63.2-0.3-1.51.10.10.5-0.70.4-1.30.9-0.6-0.7-0.61.4-1.6-1.7-1.61.8-1.4-1.41.5-1.51.71.51.4-1.4-1.5
Locomotion in novel chamber2.33.07.7-0.81.6-0.30.1-0.42.2-0.31.1-2.32.42.12.0-1.41.61.71.7-1.71.61.5-1.61.6-2.5-1.7-2.82.02.5
Locomotion in novel chamber post-restriction0.30.91.8-1.2-1.11.20.81.10.70.9-0.9-0.50.60.50.51.1-1.3-1.3-1.21.4-1.0-0.91.0-1.00.91.10.7-0.3-0.5
Fecal boli incidents, locomotor time 10.71.94.92.21.7-1.8-0.80.7-2.0-1.71.52.1-2.1-1.7-1.7-1.31.21.21.2-1.21.21.1-1.11.1-0.4-0.9-0.30.1-0.3
Change in fecal boli incidents, locomotor task1.71.83.2-0.8-1.81.20.40.6-0.11.3-1.40.2-0.3-0.7-0.71.6-1.6-1.7-1.71.6-1.7-1.41.7-1.71.51.61.7-1.6-1.4
Time >=10cm from walls, locomotor time 11.01.32.8-0.30.8-0.40.61.11.3-1.00.7-1.01.31.31.2-1.01.01.11.1-1.21.11.0-1.11.1-1.2-1.2-1.71.61.6
Bouts of movement, locomotor time 10.91.22.01.01.4-1.0-1.1-0.3-0.1-1.31.2-0.20.40.10.1-1.31.41.41.4-1.21.31.1-1.31.3-1.4-1.3-1.31.11.0
Total resting periods, locomotor time 11.51.73.41.31.7-1.3-1.5-0.3-0.3-1.91.50.00.2-0.2-0.1-1.61.61.61.6-1.41.51.4-1.51.5-1.4-1.5-1.41.31.1
Rest time, locomotor task time 10.71.14.31.40.0-0.6-2.1-1.0-1.8-1.40.11.7-1.7-1.7-1.70.1-0.2-0.4-0.30.4-0.2-0.30.3-0.30.70.31.0-0.8-1.2
Distance moved, locomotor task time 10.30.91.9-0.30.9-0.50.90.11.00.50.8-0.70.61.21.2-0.91.01.11.0-0.91.00.9-1.01.0-1.3-1.1-1.01.41.3
Vertical activity count, locomotor time 10.10.42.5-0.9-0.60.61.60.70.81.2-0.7-0.70.71.01.00.4-0.3-0.2-0.30.2-0.4-0.40.4-0.40.00.20.10.10.2
Time >=10cm from walls, locomotor time 20.10.31.20.60.2-0.6-0.80.8-0.9-1.10.31.1-0.7-0.9-0.9-0.0-0.2-0.3-0.20.00.00.00.0-0.00.70.10.0-0.0-0.6
Bouts of movement, locomotor time 20.00.10.4-0.10.4-0.2-0.2-0.70.2-0.10.2-0.0-0.00.30.2-0.20.10.10.1-0.10.30.1-0.20.2-0.4-0.20.00.30.3
Total resting periods, locomotor time 20.00.10.9-0.30.2-0.0-0.3-1.00.2-0.1-0.0-0.00.00.40.30.0-0.1-0.1-0.10.10.1-0.0-0.00.0-0.1-0.00.20.20.2
Rest time, locomotor task time 20.20.41.10.5-0.40.2-0.5-1.1-0.90.3-0.50.8-0.9-0.6-0.70.5-0.4-0.4-0.40.5-0.5-0.70.6-0.60.40.51.0-0.7-0.8
Distance moved, locomotor task time 20.60.82.8-0.60.7-0.40.91.11.10.10.7-0.80.71.31.3-0.70.60.70.6-0.60.90.8-0.80.8-0.8-0.9-1.11.71.2
Vertical activity count, locomotor time 20.10.33.10.50.2-0.60.81.8-0.30.20.50.4-0.3-0.4-0.4-0.40.40.50.4-0.40.40.4-0.30.3-0.2-0.4-0.50.40.0
Light reinforcement 11.25.411.10.32.9-1.7-0.6-0.21.6-1.72.4-1.72.01.61.6-2.52.52.52.6-2.52.72.6-2.72.7-3.0-2.7-3.13.32.9
Light reinforcement 20.92.04.8-0.41.5-0.40.2-0.41.6-0.71.0-1.61.71.51.4-1.21.51.61.6-1.61.31.4-1.31.3-2.2-1.4-1.91.61.9
Bone: marrow area1.63.99.3-3.0-2.62.92.1-0.02.32.3-2.4-2.22.02.12.12.1-2.0-1.9-1.92.1-1.9-1.91.9-1.81.01.60.6-0.4-0.0
Bone: maximum diameter0.50.92.3-1.5-1.41.50.8-0.01.40.6-1.1-1.31.21.11.11.0-0.9-0.9-0.81.1-0.8-0.80.8-0.80.20.60.00.10.2
Bone: maximum force1.73.49.8-3.1-1.92.62.2-0.43.02.2-1.9-2.83.12.82.81.4-1.1-0.9-0.91.1-1.2-1.21.2-1.1-0.20.8-0.50.21.0
Bone: maximum moment1.42.78.8-2.7-1.72.31.9-0.42.81.9-1.6-2.63.02.62.51.1-0.8-0.7-0.70.9-1.0-1.00.9-0.9-0.30.6-0.60.41.1
Mean time between licks in bursts0.32.05.6-1.20.80.21.40.52.40.00.7-1.71.92.02.1-0.91.11.21.2-1.11.11.3-1.11.2-2.0-1.2-1.71.62.1
Mean num. licks in bursts0.20.61.10.30.9-0.7-0.20.20.3-0.70.8-0.20.50.10.1-0.90.90.90.9-1.00.90.9-0.90.9-1.0-0.9-1.00.80.8
Cd content in liver2.22.410.12.31.0-1.3-3.2-2.7-2.7-0.90.52.8-2.5-2.4-2.4-0.20.40.20.30.00.0-0.20.1-0.10.30.01.0-1.0-1.4
Co content in liver0.70.83.21.10.2-0.6-1.8-1.7-1.6-0.40.01.6-1.3-1.4-1.30.2-0.1-0.1-0.10.2-0.3-0.40.3-0.30.70.30.5-0.8-1.0
Cu content in liver0.50.64.11.10.8-0.8-2.0-1.8-1.0-0.90.40.9-0.7-1.0-1.0-0.30.50.40.5-0.20.20.1-0.20.2-0.3-0.3-0.1-0.1-0.3
Fe content in liver1.62.03.90.1-1.70.81.21.6-1.21.4-1.30.9-1.1-1.3-1.31.4-1.4-1.4-1.51.4-1.5-1.51.5-1.51.91.61.5-2.0-1.9
K content in liver1.41.42.8-0.61.0-0.31.10.51.40.10.7-1.51.61.51.4-1.01.01.21.1-1.21.11.0-1.11.1-1.4-1.1-1.71.31.6
Mg content in liver0.10.10.8-0.3-0.10.30.90.60.20.7-0.2-0.50.50.20.20.2-0.1-0.1-0.1-0.0-0.2-0.20.2-0.20.20.2-0.3-0.2-0.0
Mn content in liver0.30.31.60.70.3-0.70.51.3-0.7-0.30.50.7-1.0-0.6-0.7-0.40.20.20.2-0.50.30.5-0.40.40.3-0.20.1-0.1-0.3
Na content in liver3.23.66.5-0.6-2.31.51.91.9-1.01.9-1.90.8-1.0-0.9-1.12.0-2.1-2.1-2.21.9-2.1-2.02.1-2.12.52.32.1-2.3-2.2
Rb content in liver3.54.17.60.62.4-1.7-0.7-1.11.0-1.02.0-1.21.51.21.1-2.32.52.62.5-2.42.32.1-2.32.3-2.7-2.4-2.82.52.5
Se content in liver0.10.20.40.10.5-0.4-0.5-0.50.1-0.50.4-0.10.40.10.1-0.40.40.30.4-0.50.40.4-0.40.4-0.4-0.4-0.70.50.4
Sr content in liver0.30.30.7-0.9-0.70.80.60.30.80.4-0.6-0.40.70.70.70.5-0.5-0.5-0.50.4-0.4-0.30.4-0.40.10.40.2-0.10.1
Zn content in liver0.10.10.30.40.5-0.5-0.4-0.1-0.2-0.30.50.30.2-0.1-0.2-0.40.30.40.4-0.40.40.4-0.40.4-0.3-0.4-0.40.50.2
Bone: minimum diameter1.22.28.4-2.3-1.01.71.5-0.02.90.8-0.9-2.82.92.62.60.5-0.2-0.1-0.10.3-0.3-0.20.2-0.2-0.9-0.1-1.21.01.6
Time in familiar zone, hab. session 10.10.10.50.4-0.30.1-0.1-0.2-0.60.1-0.20.3-0.4-0.5-0.50.2-0.1-0.0-0.10.1-0.2-0.30.2-0.20.40.30.3-0.7-0.5
Time in novel zone, hab. session 10.00.00.20.10.0-0.2-0.10.1-0.20.00.00.4-0.4-0.3-0.30.1-0.1-0.2-0.10.1-0.1-0.00.1-0.10.10.10.20.0-0.2
Total zone transitions, hab. session 10.10.10.20.30.2-0.40.30.3-0.30.20.40.5-0.3-0.1-0.1-0.30.20.20.2-0.20.40.3-0.30.30.0-0.2-0.1-0.00.1
Total locomotion distance, hab. session 11.11.54.5-2.1-1.01.71.5-0.62.01.7-1.0-1.82.12.12.10.7-0.6-0.4-0.50.7-0.5-0.70.5-0.5-0.00.4-0.60.40.8
Locomotion velocity, hab. session 11.31.95.8-2.3-1.21.81.8-0.22.31.9-1.0-2.12.42.32.30.8-0.6-0.4-0.50.7-0.5-0.60.5-0.5-0.20.4-0.70.41.0
Time in familiar zone, hab. session 20.60.71.40.61.0-0.90.31.2-0.1-0.91.00.00.0-0.0-0.0-1.00.90.90.9-1.11.01.1-1.01.0-0.5-0.8-1.00.60.6
Time in novel zone, hab. session 20.50.52.3-0.2-0.80.6-0.8-1.5-0.10.7-0.80.2-0.2-0.2-0.30.9-0.5-0.6-0.60.9-0.9-0.90.9-0.90.10.61.0-0.5-0.6
Total zone transitions, hab. session 20.10.10.8-0.1-0.60.20.40.9-0.00.2-0.20.1-0.1-0.2-0.20.3-0.5-0.6-0.50.5-0.2-0.20.3-0.30.40.30.3-0.3-0.3
Total locomotion distance, hab. session 20.71.03.0-1.6-0.91.21.0-0.31.71.2-0.7-1.71.71.61.60.6-0.6-0.5-0.50.5-0.4-0.40.4-0.4-0.20.2-0.40.30.7
Locomotion velocity, hab. session 20.71.02.9-1.7-1.11.31.0-0.21.61.2-0.8-1.61.61.61.60.7-0.8-0.7-0.70.7-0.5-0.50.5-0.50.10.4-0.20.20.6
Novel to familiar place preference ratio0.81.14.7-1.6-0.91.30.1-2.21.41.7-1.2-1.11.31.21.21.0-0.7-0.6-0.70.7-0.9-1.10.9-0.9-0.10.60.2-0.20.3
Novelty place preference0.70.93.7-1.4-0.91.20.1-1.91.21.6-1.1-1.01.21.01.10.9-0.5-0.5-0.50.7-0.8-1.00.8-0.8-0.20.50.2-0.20.3
Time in novel zone, NPP test0.60.73.4-1.2-0.71.00.0-1.81.21.4-0.9-1.01.21.01.00.7-0.3-0.3-0.30.5-0.6-0.80.6-0.6-0.50.30.0-0.10.4
Total zone transitions, NPP test0.20.30.70.30.6-0.8-0.10.2-0.1-0.60.80.2-0.10.30.2-0.80.40.40.4-0.70.80.8-0.80.8-0.2-0.6-0.50.50.5
Total locomotion distance, NPP test0.40.61.7-1.3-0.81.01.20.11.21.1-0.7-0.81.11.31.20.5-0.6-0.5-0.60.4-0.4-0.40.4-0.40.20.4-0.00.10.3
Locomotion velocity, NPP test0.60.92.5-1.6-1.11.21.50.41.31.3-0.8-0.91.21.41.40.7-0.8-0.7-0.80.6-0.5-0.50.5-0.50.40.50.10.10.3
Intraocular pressure1.93.14.91.81.9-2.10.22.2-0.4-1.32.20.50.0-0.5-0.5-2.22.12.22.2-2.12.12.2-2.12.1-1.9-2.0-1.81.71.3
Delta distance traveled before/after self-admin0.30.30.7-0.20.50.0-0.2-0.70.7-0.20.4-0.30.50.70.6-0.40.50.60.6-0.30.50.5-0.50.5-0.8-0.5-0.80.70.7
Delta ambulatory time before/after self-admin0.20.41.8-0.90.10.50.2-0.71.2-0.10.1-0.90.91.31.3-0.10.10.10.2-0.00.30.2-0.30.3-0.5-0.2-0.71.00.9
Parametrial fat weight0.10.21.10.50.2-0.1-0.21.0-0.5-0.40.20.8-0.7-1.0-0.8-0.00.0-0.0-0.0-0.0-0.10.10.0-0.0-0.00.20.2-0.6-0.4
Pavlov. Cond. lever latency1.62.04.20.31.7-1.00.70.51.0-0.31.3-1.01.10.90.9-1.51.81.91.8-1.71.61.6-1.61.6-2.0-1.7-1.81.51.8
Pavlov. Cond. magazine entry latency0.10.10.9-0.3-0.30.4-0.3-1.00.10.1-0.40.20.20.30.20.3-0.3-0.3-0.30.3-0.3-0.40.3-0.30.20.30.2-0.0-0.1
Pavlov. Cond. change in total contacts0.70.73.00.3-0.50.2-1.6-1.7-1.0-0.1-0.51.1-0.7-0.8-0.90.6-0.7-0.8-0.70.8-0.7-0.80.7-0.70.90.70.7-0.9-1.1
Pavlov. Cond. index score0.70.91.9-0.1-1.10.7-0.7-0.8-0.70.1-0.90.9-0.6-0.7-0.71.0-1.2-1.2-1.21.1-1.1-1.11.1-1.11.41.21.1-1.0-1.2
Pavlov. Cond. latency score1.01.32.7-0.0-1.30.7-0.7-0.6-1.00.2-1.01.1-0.9-0.9-0.91.2-1.4-1.5-1.41.3-1.2-1.21.3-1.31.61.31.4-1.2-1.5
Pavlov. Cond. lever contacts1.01.22.30.1-1.10.6-1.2-0.9-1.0-0.2-0.91.1-1.0-0.9-0.91.1-1.3-1.4-1.31.2-1.1-1.11.2-1.21.51.21.4-1.2-1.5
Pavlov. Cond. magazine entry number0.30.42.10.10.5-0.40.91.40.4-0.10.5-0.60.30.30.3-0.60.60.70.6-0.70.60.7-0.60.6-0.6-0.6-0.60.40.6
Pavlov. Cond. intertrial magazine entries0.30.31.4-0.80.00.40.2-0.31.00.2-0.2-1.21.21.01.00.00.10.20.1-0.10.1-0.0-0.10.1-0.3-0.2-0.60.20.7
Pavlov. Cond. lever-magazine prob. diff.0.40.41.0-0.1-0.70.5-0.8-1.0-0.4-0.1-0.60.6-0.3-0.3-0.30.7-0.8-0.8-0.80.7-0.7-0.70.7-0.70.90.80.7-0.6-0.8
Pavlov. Cond. response bias0.40.53.1-0.4-0.80.8-1.2-1.8-0.0-0.1-0.70.20.1-0.1-0.10.8-0.7-0.8-0.70.8-0.8-0.80.8-0.80.60.80.6-0.6-0.5
Pavlov. Cond. lever latency0.60.82.20.71.1-0.8-0.8-1.50.0-0.30.9-0.40.50.20.2-1.01.31.31.2-1.10.90.8-0.90.9-1.3-1.0-0.90.50.8
Pavlov. Cond. magazine entry latency0.50.62.4-1.0-1.01.01.61.20.61.1-0.9-0.10.30.40.40.8-0.9-0.8-0.80.8-0.8-0.70.8-0.70.60.80.4-0.5-0.3
Pavlov. Cond. change in total contacts0.51.22.0-0.5-1.41.00.10.2-0.30.8-1.20.7-0.4-0.6-0.61.3-1.3-1.4-1.31.4-1.3-1.21.3-1.31.21.31.4-1.3-1.2
Pavlov. Cond. index score0.91.42.7-1.4-1.61.51.71.40.71.2-1.4-0.20.20.40.41.4-1.5-1.5-1.41.3-1.3-1.21.3-1.21.21.31.0-0.8-0.7
Pavlov. Cond. latency score0.91.43.7-1.5-1.51.51.91.80.91.3-1.3-0.40.50.60.61.2-1.4-1.3-1.31.2-1.1-1.01.1-1.11.01.10.8-0.6-0.4
Pavlov. Cond. lever contacts0.91.32.6-0.9-1.41.10.81.2-0.10.6-1.20.4-0.5-0.2-0.21.3-1.6-1.6-1.51.4-1.3-1.21.3-1.31.61.41.1-0.9-1.1
Pavlov. Cond. magazine entry number1.31.73.51.71.7-1.8-1.9-1.0-1.0-1.81.60.6-0.7-0.7-0.7-1.51.41.31.4-1.41.41.3-1.41.4-0.9-1.3-0.80.80.5
Pavlov. Cond. intertrial magazine entries1.02.26.70.92.0-1.4-2.2-2.60.2-1.71.5-0.40.30.40.4-1.51.71.61.7-1.51.61.5-1.51.5-1.8-1.6-1.51.21.3
Pavlov. Cond. lever-magazine prob. diff.0.71.13.0-1.3-1.31.41.71.50.81.2-1.2-0.30.40.50.51.1-1.2-1.2-1.21.1-1.0-0.91.0-1.00.91.00.7-0.6-0.4
Pavlov. Cond. response bias1.52.03.5-1.4-1.91.81.41.10.41.3-1.7-0.0-0.00.20.21.7-1.8-1.8-1.81.7-1.7-1.61.7-1.61.61.71.2-1.1-1.1
Time in closed arm before self-admin0.30.51.7-0.8-0.71.1-0.0-1.20.50.9-1.0-0.81.30.20.20.8-0.4-0.3-0.40.3-0.9-1.00.8-0.80.30.8-0.1-0.9-0.2
Time in closed arm after self-admin0.50.61.1-0.1-0.80.70.0-0.4-0.60.6-0.90.5-0.4-0.6-0.70.9-0.8-0.7-0.80.9-0.9-1.00.9-0.91.00.91.0-1.0-0.9
Time in open arm before self-admin0.10.10.4-0.10.1-0.2-0.30.30.3-0.60.4-0.10.00.10.0-0.2-0.1-0.2-0.10.10.30.4-0.20.2-0.0-0.2-0.10.60.2
Time in open arm after self-admin0.30.31.0-0.1-0.90.40.31.0-0.10.2-0.40.7-0.4-0.0-0.10.6-0.7-0.8-0.70.7-0.6-0.40.6-0.60.60.60.8-0.2-0.6
Bone: periosteal estimation2.04.711.5-3.4-2.83.32.2-0.42.72.3-2.6-2.62.52.52.42.3-2.1-2.0-1.92.1-2.0-2.02.0-2.00.81.70.4-0.20.2
Bone: periosteal perimeter1.22.46.8-2.6-1.72.31.0-1.22.41.4-1.7-2.42.32.22.21.4-1.2-1.1-1.11.4-1.2-1.31.2-1.20.10.90.00.30.6
Bone: post-yield work0.61.02.9-1.6-1.01.21.60.61.71.1-0.8-1.51.61.71.70.5-0.5-0.5-0.40.6-0.4-0.40.4-0.3-0.20.2-0.30.60.7
Progressive ratio test 1 active lever presses0.40.68.2-0.60.70.1-1.3-2.90.80.10.1-0.80.80.90.9-0.20.30.30.4-0.40.30.1-0.30.3-0.6-0.3-0.80.40.7
Progressive ratio test 1 breakpoint0.40.68.6-0.70.60.2-1.3-2.90.80.10.0-0.90.91.01.0-0.10.20.20.2-0.30.20.0-0.20.2-0.5-0.2-0.70.30.7
Progressive ratio test 1 inactive lever presses0.20.62.6-1.3-0.41.0-0.5-1.60.90.6-0.7-0.80.71.11.10.7-0.9-0.9-0.80.8-0.5-0.70.6-0.60.40.60.30.00.1
Progressive ratio test 2 active lever presses0.50.66.9-0.40.8-0.2-1.6-2.60.5-0.90.3-0.70.20.90.9-0.40.20.20.3-0.40.50.3-0.40.4-0.4-0.4-0.50.80.7
Progressive ratio test 2 breakpoint0.60.76.6-0.31.0-0.3-1.7-2.60.5-1.00.5-0.60.20.80.8-0.50.40.40.5-0.60.70.5-0.60.6-0.6-0.6-0.70.90.8
Progressive ratio test 2 inactive lever presses0.10.43.8-0.8-0.20.6-1.2-2.00.60.4-0.3-0.40.50.50.50.5-0.5-0.6-0.50.6-0.4-0.40.5-0.50.10.40.3-0.2-0.1
Incentive Sensitization - Responses0.10.21.0-0.30.10.0-0.9-0.80.0-1.0-0.1-0.1-0.50.50.40.1-0.5-0.6-0.50.20.0-0.10.0-0.00.50.10.30.6-0.0
Incentive Sensitization - Breakpoint0.10.21.2-0.20.3-0.2-0.8-0.7-0.0-1.10.1-0.0-0.50.40.4-0.2-0.2-0.4-0.2-0.10.20.1-0.20.20.3-0.10.20.80.1
Sum of active levers in priming session hrs 5-61.91.84.4-2.1-1.21.81.4-0.21.31.6-1.6-1.41.01.41.51.4-1.5-1.5-1.51.3-1.3-1.41.3-1.31.11.30.9-0.4-0.2
Progressive ratio0.10.20.6-0.20.4-0.10.2-0.70.5-0.30.1-0.60.50.60.6-0.40.60.60.6-0.80.40.3-0.40.4-0.5-0.4-0.70.20.6
Food seeking constrained by brief footshock2.32.95.8-0.41.6-0.71.00.41.80.01.2-2.12.22.01.9-1.51.81.91.8-1.91.71.5-1.71.7-2.3-1.8-2.32.12.4
Seeking ratio, punishment vs. effort0.40.82.1-0.60.60.10.90.61.30.60.4-1.31.51.41.4-0.60.60.70.6-0.50.70.6-0.70.7-1.2-0.8-1.01.41.3
Retroperitoneal fat weight0.10.61.8-1.3-0.81.21.00.11.21.3-0.8-0.90.70.80.90.8-0.7-0.6-0.70.9-0.7-0.70.7-0.70.10.60.4-0.20.1
Reaction time number correct0.10.41.40.30.8-0.6-1.0-1.20.1-0.30.7-0.30.40.10.1-0.60.70.70.7-0.50.70.6-0.60.6-1.0-0.7-0.80.60.6
Reaction time mean minus median0.31.76.4-1.0-1.91.62.10.90.42.5-1.6-0.20.20.30.11.5-1.1-1.0-1.11.3-1.5-1.51.5-1.50.91.31.0-1.1-0.8
Reaction time mean minus median AUC0.21.45.5-0.8-1.81.41.70.70.32.3-1.40.10.10.1-0.11.4-1.0-0.9-1.11.3-1.4-1.31.4-1.40.81.21.1-1.1-0.9
Reaction time num false alarms0.30.52.00.01.0-0.50.91.40.3-0.20.7-0.70.10.50.5-0.70.50.60.5-0.80.80.8-0.80.8-0.5-0.6-0.61.00.7
Reaction time num false alarms AUC0.10.33.1-0.20.6-0.31.01.80.4-0.30.5-0.60.10.60.5-0.40.20.20.2-0.40.50.6-0.50.5-0.1-0.3-0.40.80.5
Reaction time trials correct on left0.10.41.40.30.8-0.6-1.0-1.20.1-0.30.7-0.30.40.10.1-0.60.70.70.7-0.50.70.6-0.60.6-1.0-0.7-0.80.60.6
Reaction time trials on left0.10.41.50.30.7-0.5-0.9-1.20.1-0.30.6-0.30.40.10.1-0.60.60.60.7-0.40.60.5-0.60.6-0.9-0.7-0.70.60.5
Reaction time mean1.94.19.5-2.2-2.92.72.40.61.13.1-2.6-1.00.91.10.92.4-2.1-2.0-2.12.2-2.4-2.42.3-2.31.62.01.5-1.3-1.0
Reaction time mean AUC1.33.07.4-1.9-2.62.42.00.41.02.7-2.3-0.80.80.80.72.1-1.8-1.7-1.81.9-2.1-2.02.0-2.01.31.71.3-1.2-0.8
Median of all reaction times2.13.37.0-2.0-2.72.51.90.31.02.5-2.3-0.90.80.90.82.2-2.0-1.9-2.02.0-2.1-2.12.1-2.11.51.81.4-1.1-0.9
Reaction time omissions1.01.73.1-1.1-1.81.41.50.80.11.4-1.40.1-0.40.20.01.5-1.6-1.6-1.61.7-1.4-1.41.5-1.41.61.41.5-0.8-1.1
Reaction time false alarm rate0.20.35.2-0.20.3-0.11.32.30.2-0.20.2-0.3-0.10.30.2-0.2-0.1-0.1-0.1-0.20.20.3-0.20.20.3-0.0-0.00.40.1
Reaction time premature initiation rate0.40.61.50.60.9-0.91.01.2-0.20.00.80.1-0.20.00.0-0.90.91.00.9-0.90.90.8-0.90.9-0.5-0.8-0.70.80.5
Reaction time premature initiations0.20.71.30.51.1-1.00.40.4-0.0-0.20.9-0.20.00.20.2-1.01.11.11.1-0.91.00.9-1.01.0-0.8-1.0-1.01.10.8
Std. dev. reaction times1.03.29.2-1.9-2.52.42.60.91.03.0-2.3-0.70.71.00.82.1-1.8-1.7-1.81.9-2.0-2.02.0-2.01.21.81.4-1.0-0.8
Reaction time trials completed0.10.41.50.30.7-0.5-0.9-1.20.1-0.30.6-0.30.40.10.1-0.60.60.60.7-0.40.60.5-0.60.6-0.9-0.7-0.70.60.5
Reaction time trials AUC0.10.30.80.30.7-0.6-0.8-0.9-0.0-0.20.6-0.10.2-0.1-0.0-0.50.60.60.6-0.40.60.5-0.50.5-0.8-0.6-0.70.60.4
Run reversals in cocaine runway, females1.71.94.1-0.11.3-0.3-0.2-1.51.4-0.40.8-1.91.81.21.3-1.21.71.81.7-1.51.21.1-1.21.3-2.0-1.3-1.91.11.9
Run reversals in cocaine runway, males1.11.22.71.20.9-1.2-0.90.8-0.1-1.61.50.40.1-0.5-0.6-1.21.21.11.2-1.01.21.5-1.21.2-1.2-1.3-1.21.20.7
Latency to leave start box in cocaine runway0.50.71.20.31.0-0.9-0.20.10.4-0.70.9-0.50.40.30.4-1.01.01.00.9-1.11.01.0-1.01.0-0.9-1.0-0.80.80.9
Latency to leave start box in cocaine runway, F1.41.83.30.71.8-1.4-0.4-0.10.2-1.51.6-0.40.00.50.5-1.71.61.61.5-1.81.71.7-1.71.7-1.3-1.6-1.21.51.4
Latency to leave start box in cocaine runway, M0.10.10.3-0.5-0.40.40.10.30.40.5-0.4-0.50.50.10.20.4-0.4-0.4-0.40.4-0.4-0.30.4-0.40.20.30.2-0.3-0.0
Std. dev. time between licks in bursts0.10.20.6-0.00.2-0.30.0-0.00.4-0.30.4-0.70.50.30.4-0.50.40.50.5-0.60.50.5-0.50.5-0.4-0.5-0.80.40.6
Total sessions with >9 infusions0.50.66.0-0.80.20.5-1.1-2.51.10.1-0.1-1.11.11.21.10.10.10.00.1-0.00.0-0.10.0-0.0-0.5-0.1-0.40.70.7
Short access day 1 total inactive lever presses0.30.62.1-1.00.20.4-0.1-0.61.4-0.10.2-1.31.41.41.4-0.10.10.00.1-0.00.30.3-0.30.3-0.6-0.4-0.61.21.0
Short access day 10 total inactive lever presses0.10.62.20.8-0.4-0.2-0.41.0-1.1-0.3-0.01.5-0.9-1.2-1.30.3-0.4-0.5-0.40.4-0.4-0.20.4-0.40.80.50.5-1.2-1.1
Short access day 1 total infusions0.40.73.0-1.3-0.10.8-0.7-1.71.40.3-0.2-1.31.41.41.50.3-0.3-0.4-0.30.4-0.1-0.20.2-0.1-0.30.0-0.51.10.8
Short access day 10 total infusions0.61.18.50.81.1-0.8-2.3-2.9-0.3-0.70.90.00.5-0.4-0.4-0.81.11.11.1-1.00.70.6-0.70.7-1.0-0.7-1.00.30.5
Short access total infusions0.40.67.50.20.6-0.3-2.1-2.70.1-0.30.4-0.20.50.00.0-0.30.50.40.5-0.30.30.2-0.20.2-0.6-0.3-0.60.40.3
Short access day 1 locomotion1.01.66.4-1.80.11.2-0.2-1.82.50.5-0.3-2.02.32.22.30.10.20.20.3-0.10.10.0-0.10.1-1.3-0.3-1.11.41.6
Short access day 10 total locomotion0.10.20.50.20.6-0.30.10.20.2-0.10.4-0.40.40.30.3-0.50.60.60.6-0.70.50.5-0.50.5-0.6-0.5-0.70.20.5
Short access total locomotion0.61.02.5-0.90.70.2-0.3-1.51.50.00.3-1.51.61.61.6-0.50.60.70.7-0.70.60.5-0.60.6-1.1-0.7-1.11.21.4
One hour access (0.3 mA shock)1.51.78.1-1.7-1.11.6-0.8-2.81.01.3-1.6-1.21.01.11.11.4-1.3-1.3-1.31.2-1.3-1.61.4-1.40.81.20.7-0.6-0.2
Compulsive drug intake0.60.84.1-0.30.1-0.11.22.01.3-0.10.5-1.10.90.80.9-0.60.60.60.7-0.40.71.0-0.80.8-1.3-0.9-0.91.21.2
One hour access (shock baseline)0.82.213.9-1.1-1.01.4-1.7-3.7-0.10.9-1.6-0.20.30.20.21.6-1.4-1.5-1.51.3-1.6-1.91.6-1.71.51.71.2-1.5-1.1
Social response proportion0.70.92.31.21.1-1.3-1.4-0.2-0.6-1.51.10.3-0.1-0.7-0.8-1.01.11.01.1-1.10.90.9-0.90.9-0.8-0.9-1.00.70.3
Social responses0.30.43.40.80.5-0.7-1.9-0.8-0.8-1.50.50.2-0.2-0.9-1.0-0.30.20.00.2-0.30.20.2-0.20.20.1-0.1-0.3-0.0-0.3
Social time1.01.65.1-0.3-1.40.8-2.1-2.3-0.5-0.1-1.30.10.2-0.7-0.81.3-1.3-1.4-1.31.2-1.5-1.51.5-1.51.41.31.0-1.6-1.3
Soleus weight1.54.48.2-0.31.8-1.00.81.12.1-0.71.7-2.62.92.02.0-2.02.12.32.2-2.22.22.2-2.22.2-2.8-2.3-2.82.52.9
Bone: stiffness1.01.85.7-2.3-1.31.81.6-0.22.31.5-1.3-2.12.42.12.10.9-0.7-0.7-0.60.7-0.8-0.70.7-0.7-0.30.5-0.50.20.8
Tibialis anterior weight2.910.116.70.63.6-2.60.71.52.0-1.63.3-2.42.22.22.3-3.63.53.73.6-3.63.83.7-3.83.8-4.0-3.8-3.94.14.0
Time to tail flick, vehicle, before self-admin0.20.21.30.4-0.40.2-0.5-0.3-0.4-0.3-0.30.30.4-1.1-1.00.20.20.20.2-0.2-0.5-0.20.3-0.30.00.4-0.2-1.1-0.5
Time to tail flick, vehicle, after self-admin0.10.20.90.90.4-0.5-0.4-0.4-0.8-0.20.10.7-0.4-0.7-0.6-0.30.60.60.6-0.50.10.1-0.20.2-0.3-0.2-0.1-0.5-0.2
Time to tail flick, test, before self-admin1.31.54.2-1.00.80.00.6-0.71.80.20.6-1.62.01.91.9-0.80.80.90.9-0.91.00.8-1.01.0-1.3-1.0-1.72.11.8
Time to tail flick, test, after self-admin0.60.62.9-0.70.20.4-0.1-1.01.30.60.0-1.31.71.11.2-0.20.40.50.5-0.20.30.2-0.30.3-1.0-0.5-1.00.91.1
Delta time to tail flick, vehicle, before/after SA0.10.10.40.20.3-0.20.4-0.2-0.20.40.10.3-0.70.30.3-0.10.10.10.10.10.2-0.0-0.10.1-0.0-0.20.30.30.1
Delta time to tail flick, test, before/after SA0.60.73.11.3-0.2-0.3-1.5-0.2-1.4-0.40.01.2-0.9-1.8-1.70.20.10.00.10.3-0.4-0.20.3-0.30.10.20.4-1.3-1.0
Tibia length2.67.114.4-3.5-3.43.63.20.51.93.8-3.4-1.61.61.81.83.1-3.0-2.9-2.93.0-2.9-3.02.9-2.92.12.81.7-1.5-1.1
Ambulatory time before self-admin0.92.75.4-1.6-2.31.91.40.50.51.9-2.0-0.30.20.50.52.0-2.1-2.1-2.12.0-1.9-1.91.9-1.91.91.81.8-1.0-1.1
Ambulatory time after self-admin0.50.82.0-1.4-1.21.30.6-0.10.90.6-1.0-0.20.31.01.01.0-1.2-1.3-1.21.2-0.8-0.90.8-0.80.90.80.90.2-0.2
Bone: tissue strength0.60.72.10.60.9-0.6-1.0-0.90.3-0.80.80.10.40.10.0-0.91.10.91.1-0.80.80.8-0.80.8-1.5-0.9-0.80.70.9
Total heroin consumption0.10.10.4-0.30.10.1-0.2-0.60.40.5-0.1-0.70.30.10.20.1-0.00.0-0.1-0.1-0.1-0.00.0-0.0-0.3-0.00.40.00.2
Bone: trabecular number1.01.93.7-0.8-1.91.51.10.7-0.41.4-1.70.5-0.4-0.4-0.41.7-1.6-1.6-1.61.5-1.7-1.81.7-1.71.71.71.2-1.5-1.4
Bone: trabecular spacing0.40.61.41.01.2-1.1-1.2-0.8-0.8-1.00.90.7-0.8-0.4-0.4-0.80.70.70.7-0.70.80.7-0.80.8-0.2-0.7-0.10.60.1
Bone: trabecular thickness3.04.17.5-1.1-2.72.10.6-0.3-0.51.9-2.40.6-0.6-0.7-0.72.5-2.5-2.5-2.52.4-2.5-2.52.5-2.52.42.52.1-2.3-2.1
Bone: trabecular tissue density0.91.64.2-1.6-1.71.52.01.30.81.4-1.3-0.40.40.80.81.4-1.6-1.5-1.61.5-1.2-1.11.2-1.21.51.20.9-0.4-0.6
Water consumed over 24 hours0.51.02.80.6-0.2-0.1-1.2-0.6-1.6-0.4-0.41.5-1.7-1.3-1.30.7-0.8-1.0-0.90.8-0.8-0.80.8-0.81.30.91.4-1.0-1.5
Number of responses in last shaping day0.50.71.3-1.0-0.91.20.2-0.60.71.1-1.0-0.61.00.60.70.9-0.8-0.8-0.80.8-0.9-0.90.9-0.90.50.90.6-0.5-0.2