Ifih1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Ifih1 0.06 0.05 1.7e-05 0.06 0.06 0.06 0.05 2.3e-05 3.0e-05 2.6e-05 5.2e-05
2 NAcc gene expression Ifih1 0.08 0.06 6.2e-12 0.09 0.08 0.08 0.09 2.2e-13 3.9e-12 1.6e-12 5.7e-13
3 Brain gene expression Ifih1 0.14 0.07 0.0e+00 0.21 0.22 0.22 0.22 1.2e-19 2.0e-20 3.5e-20 9.8e-21
4 Eye alternative TSS XM_039105671.2 0.28 0.17 6.8e-03 0.12 0.07 0.12 0.06 7.3e-03 2.8e-02 8.0e-03 3.9e-02
5 Adipose isoform ratio XM_039105671.2 0.06 0.04 1.1e-07 0.05 0.06 0.06 0.06 1.8e-06 3.3e-07 2.4e-07 4.5e-07
6 Adipose mRNA stability Ifih1 0.13 0.07 0.0e+00 0.14 0.14 0.13 0.13 5.3e-15 4.3e-15 5.0e-14 1.8e-14
7 Brain alternative TSS NM_001109199.1 0.02 0.02 9.0e-03 0.01 0.01 0.01 0.01 3.7e-02 1.7e-02 4.2e-02 4.1e-02
8 Adipose alternative polyA XM_063284355.1 0.07 0.06 2.0e-05 0.03 0.04 0.04 0.03 1.9e-04 6.4e-05 7.9e-05 1.0e-04
9 PL gene expression Ifih1 0.02 0.01 9.5e-03 0.01 0 0 0 2.3e-02 8.3e-02 2.5e-01 1.9e-01
10 Adipose gene expression Ifih1 0.22 0.11 0.0e+00 0.22 0.22 0.21 0.22 4.4e-24 7.5e-24 2.1e-23 9.1e-24
11 Adipose isoform ratio NM_001109199.1 0.03 0.03 6.6e-04 0.01 0.01 0.01 0.01 1.1e-02 1.2e-02 2.8e-02 1.5e-02
12 PL alternative TSS XM_039105671.2 0.02 0.02 4.5e-03 0.01 0.02 0.01 0.02 9.2e-03 5.6e-03 1.1e-02 6.9e-03
13 IC alternative polyA NM_001109199.1 0.08 0.06 1.8e-03 0.05 0.06 0.04 0.04 2.9e-03 1.4e-03 8.6e-03 8.1e-03
14 Brain alternative TSS XM_039105671.2 0.06 0.04 6.2e-06 0.06 0.05 0.04 0.04 4.6e-06 3.2e-05 1.5e-04 6.5e-05
15 Brain mRNA stability Ifih1 0.05 0.03 1.3e-05 0.06 0.06 0.05 0.05 7.2e-06 5.3e-06 3.0e-05 1.2e-05
16 IC alternative polyA XM_063284355.1 0.08 0.06 3.1e-03 0.05 0.05 0.04 0.04 3.8e-03 2.6e-03 1.3e-02 1.2e-02
17 IC gene expression Ifih1 0.13 0.09 7.4e-05 0.08 0.11 0.09 0.08 2.6e-04 3.4e-05 1.9e-04 3.4e-04
18 Adipose alternative TSS NM_001109199.1 0.03 0.02 4.2e-04 0.03 0.03 0.02 0.02 7.3e-04 4.3e-04 8.8e-04 1.1e-03
19 Liver gene expression Ifih1 0.23 0.1 0.0e+00 0.28 0.29 0.29 0.29 1.0e-30 1.0e-32 4.0e-32 2.5e-32
20 Adipose alternative TSS XM_039105671.2 0.05 0.03 1.5e-06 0.05 0.05 0.05 0.05 5.9e-06 1.4e-06 4.2e-06 4.3e-06
21 Brain alternative TSS XM_039105671.2 0.06 0.04 1.5e-05 0 0.02 0.01 0.01 1.3e-01 3.1e-03 7.4e-02 3.7e-02
22 Brain alternative TSS XM_063284355.1 0.06 0.04 1.5e-05 0 0.02 0.01 0.01 1.4e-01 3.0e-03 7.3e-02 3.7e-02
23 Adipose alternative TSS XM_063284355.1 0.05 0.04 1.7e-06 0.05 0.05 0.05 0.05 7.4e-06 1.6e-06 4.6e-06 4.1e-06
24 Adipose alternative TSS XM_039105671.2 0.07 0.04 8.3e-09 0.07 0.07 0.07 0.07 7.1e-08 1.5e-08 1.3e-08 2.0e-08
25 BLA gene expression Ifih1 0.12 0.08 2.7e-06 0.09 0.09 0.09 0.09 2.9e-05 2.6e-05 1.2e-05 2.4e-05
26 Adipose alternative polyA NM_001109199.1 0.07 0.07 1.3e-05 0.03 0.04 0.04 0.04 1.1e-04 4.1e-05 4.1e-05 6.5e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.10.20.9-0.8-0.80.60.70.50.30.4-0.4-0.4-0.2-0.2-0.30.30.50.3-0.30.20.20.2-0.3-0.20.20.30.4-1.00.3
Area under the delay curve0.20.40.80.50.5-0.4-0.4-0.6-0.5-0.40.80.50.50.50.3-0.7-0.4-0.70.7-0.7-0.8-0.70.80.9-0.9-0.9-0.60.00.4
BMI with tail0.00.10.20.10.10.10.00.40.10.1-0.3-0.20.10.1-0.10.20.40.2-0.20.20.30.2-0.3-0.30.30.30.2-0.4-0.2
BMI without tail0.31.31.7-1.2-1.21.21.31.21.21.1-1.2-1.3-1.1-1.1-1.11.21.31.2-1.21.21.21.2-1.2-1.21.21.21.2-1.0-0.3
Body weight0.20.81.1-0.8-0.80.91.00.90.90.9-0.9-1.0-0.9-0.9-0.90.91.10.9-0.90.90.90.9-0.9-0.80.80.90.9-0.9-0.5
Weight adjusted by age0.51.62.41.21.2-1.1-1.3-1.5-1.1-1.01.51.11.11.10.9-1.3-1.3-1.31.3-1.3-1.4-1.21.51.5-1.5-1.5-1.30.31.1
Bone surface0.81.65.6-1.6-1.61.51.51.31.21.3-1.1-1.3-1.1-1.1-1.31.11.41.1-1.11.01.01.0-0.9-0.90.90.91.1-2.4-0.2
Bone volume0.40.82.6-1.2-1.21.11.11.00.80.9-0.9-0.9-0.6-0.6-0.80.81.00.8-0.80.70.70.6-0.7-0.70.70.70.8-1.6-0.4
Breakpoint value in progressive ratio session4.68.211.93.43.4-3.3-3.4-3.0-3.2-3.32.83.03.03.03.3-2.8-3.4-2.92.8-2.7-2.5-2.72.42.4-2.4-2.4-2.91.9-0.3
Number of licking bursts0.00.10.4-0.2-0.20.0-0.10.30.1-0.0-0.4-0.4-0.3-0.30.10.4-0.30.3-0.40.40.50.4-0.6-0.60.60.60.30.50.2
Context. condit. distance diff. score0.10.11.5-0.3-0.3-0.10.2-0.3-0.00.10.4-0.00.00.0-0.2-0.2-0.2-0.20.2-0.2-0.4-0.20.40.5-0.5-0.5-0.20.71.2
Locomotion velocity, session 10.50.61.3-0.4-0.40.20.30.60.60.4-0.8-0.7-0.8-0.8-0.50.90.10.9-0.91.01.01.0-1.1-1.11.11.10.80.5-0.4
Locomotion distance, session 10.10.10.2-0.5-0.50.20.20.10.30.2-0.1-0.2-0.5-0.5-0.30.20.20.3-0.20.30.30.3-0.2-0.20.20.20.20.0-0.1
Locomotion velocity, session 21.72.02.61.61.6-1.3-1.4-1.5-1.5-1.41.41.61.41.41.4-1.5-1.1-1.51.5-1.6-1.5-1.61.51.5-1.5-1.5-1.50.6-0.1
Locomotion distance, session 20.10.10.5-0.5-0.50.60.50.20.40.4-0.2-0.1-0.5-0.5-0.40.20.70.2-0.20.10.10.2-0.0-0.00.00.00.1-0.7-0.6
Locomotion velocity, session 30.60.60.90.60.6-0.7-0.7-0.8-0.8-0.80.80.70.80.80.8-0.9-0.4-0.90.9-0.9-0.9-0.90.90.9-0.9-1.0-0.90.30.6
Locomotion distance, session 30.40.41.0-1.0-1.00.81.00.50.70.9-0.3-0.7-0.7-0.7-0.90.40.90.5-0.50.40.20.4-0.2-0.10.10.10.4-0.60.7
Stereotopy head waving bouts, day 30.30.31.4-0.3-0.30.70.70.60.50.5-0.7-0.3-0.4-0.4-0.40.50.90.4-0.40.40.40.3-0.4-0.40.40.40.4-0.9-1.2
Stereotopy head waving duration, day 30.10.11.50.10.10.20.20.30.1-0.0-0.50.0-0.0-0.00.10.20.40.2-0.20.20.30.1-0.4-0.40.40.40.1-0.2-1.2
Locomotion velocity, session 70.00.00.2-0.0-0.0-0.1-0.1-0.00.00.00.1-0.2-0.0-0.0-0.1-0.00.2-0.00.0-0.0-0.1-0.00.10.1-0.1-0.10.0-0.10.5
Locomotion distance, session 70.00.00.50.10.1-0.2-0.10.0-0.1-0.1-0.00.00.00.00.10.0-0.20.0-0.00.10.10.1-0.1-0.10.10.10.00.70.1
Stereotopy head waving bouts, day 70.10.10.5-0.4-0.40.20.3-0.00.30.4-0.0-0.4-0.4-0.4-0.40.20.00.3-0.20.30.10.3-0.1-0.10.10.10.20.10.7
Stereotopy head waving duration, day 70.10.10.3-0.3-0.30.30.20.10.40.5-0.1-0.4-0.5-0.5-0.50.30.10.4-0.40.40.30.4-0.2-0.20.20.20.3-0.30.4
Locomotion velocity, session 80.10.10.30.50.5-0.2-0.2-0.4-0.2-0.20.40.20.10.10.2-0.3-0.3-0.30.3-0.3-0.4-0.30.40.4-0.4-0.4-0.30.1-0.3
Locomotion distance, session 80.20.20.9-0.0-0.0-0.2-0.0-0.6-0.3-0.20.70.30.20.20.1-0.5-0.3-0.50.5-0.5-0.6-0.50.70.7-0.7-0.7-0.50.51.0
Degree of sensitization distance1.01.12.11.41.4-1.3-1.3-1.0-1.2-1.30.91.11.11.11.3-0.9-1.4-0.90.9-0.8-0.7-0.80.60.6-0.6-0.6-0.91.5-0.0
Degree of sensitization stereotypy0.10.21.80.00.0-0.3-0.2-0.6-0.1-0.10.60.00.00.0-0.0-0.3-0.5-0.20.2-0.2-0.4-0.10.40.4-0.4-0.4-0.20.51.3
Conditioned locomotion1.51.83.60.90.9-0.8-0.9-1.5-1.0-0.81.61.31.01.00.7-1.5-0.7-1.41.5-1.5-1.7-1.51.91.9-1.9-1.9-1.5-0.61.1
Cocaine response after cond. corrected5.37.911.63.13.1-3.3-3.2-2.7-3.2-3.42.53.13.03.03.4-2.8-3.0-2.82.8-2.8-2.5-2.82.32.2-2.2-2.3-2.73.10.4
Cocaine response after cond. not corrected3.75.47.72.52.5-2.8-2.7-2.3-2.6-2.82.12.42.42.42.8-2.3-2.6-2.42.3-2.3-2.1-2.32.01.9-1.9-1.9-2.32.20.6
Cocaine response before conditioning1.51.85.9-1.5-1.51.41.11.01.51.6-0.8-1.7-1.4-1.4-1.71.21.01.3-1.31.31.01.3-0.9-0.80.90.91.3-2.40.7
Saline control response0.20.20.40.20.2-0.4-0.4-0.4-0.5-0.50.30.50.50.50.6-0.5-0.5-0.50.5-0.5-0.4-0.50.40.4-0.4-0.4-0.50.70.5
Bone: connectivity density0.10.21.2-0.9-0.90.70.70.40.40.5-0.3-0.4-0.3-0.3-0.50.30.50.3-0.30.20.20.2-0.1-0.10.10.10.4-1.10.6
Bone: cortical apparent density0.30.41.0-0.4-0.40.50.40.80.40.3-0.9-0.4-0.4-0.4-0.20.70.40.7-0.70.70.90.6-0.9-1.01.01.00.6-0.0-0.8
Bone: cortical area3.55.78.6-2.9-2.92.42.62.42.42.4-2.3-2.6-2.5-2.5-2.42.52.12.5-2.52.52.52.5-2.4-2.42.42.42.5-0.8-0.1
Bone: cortical porosity1.71.82.1-1.2-1.21.21.11.41.41.4-1.3-1.4-1.4-1.4-1.41.41.21.4-1.41.51.41.5-1.4-1.41.41.41.4-1.0-0.8
Bone: cortical porosity4.14.55.3-2.1-2.12.01.92.32.22.2-2.2-2.3-2.1-2.1-2.22.22.12.2-2.22.32.22.2-2.2-2.22.22.22.2-1.6-0.9
Bone: cortical thickness3.15.27.1-2.7-2.72.32.32.52.22.1-2.5-2.2-2.2-2.2-2.02.42.42.4-2.42.32.42.3-2.5-2.52.52.52.4-0.8-0.7
Bone: cortical thickness6.17.410.3-3.2-3.22.93.02.92.82.7-2.9-2.7-2.7-2.7-2.62.83.02.8-2.82.72.72.6-2.7-2.72.72.72.6-1.8-1.3
Bone: cortical tissue density0.20.30.8-0.3-0.30.40.30.70.40.2-0.8-0.3-0.3-0.3-0.10.60.30.6-0.60.60.80.6-0.9-0.90.90.90.50.0-0.8
Condit. Reinf. active minus inactive responses4.95.67.8-2.8-2.82.32.42.32.62.6-2.1-2.7-2.6-2.6-2.62.42.32.5-2.42.42.32.5-2.2-2.12.22.22.4-1.5-0.0
Condit. Reinf. active-inactive response ratio1.92.03.3-1.7-1.71.41.51.21.61.7-1.1-1.8-1.6-1.6-1.71.41.21.4-1.41.41.21.5-1.2-1.11.11.11.4-1.40.4
Condit. Reinf. active responses4.35.56.5-2.5-2.52.42.52.52.52.4-2.4-2.4-2.5-2.5-2.42.42.62.4-2.42.42.32.4-2.3-2.32.32.32.3-1.6-1.0
Condit. Reinf. inactive responses2.22.97.8-1.2-1.21.81.62.11.51.3-2.3-1.1-1.4-1.4-1.11.72.11.6-1.71.51.81.5-1.9-2.02.01.91.4-1.2-2.8
Incentive salience index mean4.76.08.6-2.9-2.92.32.52.42.62.6-2.2-2.9-2.7-2.7-2.72.52.42.5-2.52.62.42.6-2.3-2.32.32.32.5-1.60.3
Condit. Reinf. lever presses0.71.01.7-1.3-1.30.80.91.11.01.0-0.9-1.3-1.0-1.0-1.01.00.91.0-1.01.11.01.0-1.0-1.01.01.01.1-0.50.8
Condit. Reinf. active minus inactive responses1.82.74.6-2.0-2.02.11.71.61.92.1-1.3-1.8-1.8-1.8-2.11.61.81.6-1.61.61.31.6-1.2-1.11.11.11.6-2.10.4
Condit. Reinf. active-inactive response ratio1.01.63.1-1.5-1.51.71.51.21.51.7-0.9-1.4-1.4-1.4-1.81.21.51.2-1.21.20.91.2-0.8-0.70.70.71.3-1.60.5
Condit. Reinf. active responses1.82.64.0-1.9-1.91.91.51.61.81.9-1.4-1.8-1.7-1.7-2.01.61.51.6-1.61.61.51.6-1.4-1.31.31.31.6-2.00.2
Condit. Reinf. inactive responses0.00.00.2-0.0-0.0-0.0-0.30.2-0.0-0.1-0.2-0.00.00.00.10.1-0.20.1-0.10.10.20.1-0.3-0.30.30.30.1-0.4-0.1
Condit. Reinf. lever presses1.42.12.7-1.5-1.51.31.11.41.61.5-1.3-1.6-1.5-1.5-1.61.51.01.6-1.61.61.51.6-1.5-1.41.41.51.6-1.50.1
Condit. Reinf. lever reinforcers received1.11.52.6-1.5-1.51.41.01.21.41.5-1.0-1.4-1.3-1.3-1.51.21.11.2-1.21.21.11.3-1.0-0.90.91.01.3-1.60.5
Conditioned reinforcement - actives0.52.23.2-1.3-1.31.41.41.51.51.4-1.5-1.5-1.5-1.5-1.41.61.21.5-1.61.61.61.5-1.6-1.61.61.61.3-1.8-1.2
Conditioned reinforcement - inactives0.10.21.9-0.3-0.30.60.50.50.40.3-0.5-0.2-0.5-0.5-0.30.40.40.4-0.40.30.40.3-0.4-0.40.40.40.1-0.8-1.4
Conditioned locomotion0.10.11.50.20.2-0.1-0.10.1-0.2-0.3-0.20.20.10.10.4-0.1-0.0-0.10.1-0.10.1-0.1-0.1-0.20.20.2-0.2-0.3-1.2
Patch foraging indifference point 0 sec0.00.10.4-0.2-0.20.30.10.60.20.1-0.6-0.0-0.1-0.10.00.40.40.3-0.30.30.50.3-0.5-0.60.60.60.40.3-0.4
Patch foraging indifference point AUC0.10.11.10.00.00.10.0-0.20.20.40.4-0.2-0.1-0.1-0.5-0.10.0-0.10.1-0.1-0.3-0.10.40.5-0.5-0.50.1-0.91.1
Delay disc. indifference point, 0s delay0.10.10.4-0.1-0.10.10.10.3-0.0-0.1-0.40.0-0.1-0.10.20.20.00.2-0.20.20.30.1-0.4-0.40.40.40.20.4-0.7
Delay disc. indifference point, 16s delay0.10.10.6-0.1-0.10.50.50.30.30.4-0.3-0.2-0.2-0.2-0.30.20.60.2-0.20.10.10.1-0.1-0.10.10.10.2-0.6-0.8
Delay disc. indifference point, 2s delay0.30.30.8-0.7-0.70.70.70.70.50.6-0.5-0.4-0.5-0.5-0.60.40.70.5-0.40.40.40.4-0.4-0.30.30.40.5-0.9-0.0
Delay disc. indifference point, 24s delay0.60.91.71.01.0-0.8-0.7-1.0-0.8-0.61.30.90.80.80.5-1.1-0.7-1.01.0-1.0-1.2-1.01.31.3-1.3-1.3-0.90.30.7
Delay disc. indifference point, 4s delay1.01.12.00.80.8-0.9-0.8-1.2-0.8-0.61.40.70.80.80.5-1.1-0.9-1.01.1-1.0-1.3-1.01.41.4-1.4-1.4-1.00.21.2
Delay disc. indifference point, 8s delay0.30.61.10.60.6-0.6-0.5-0.9-0.6-0.51.00.50.60.60.4-0.8-0.6-0.80.8-0.8-0.9-0.81.01.0-1.0-1.0-0.80.10.7
Indifference point function ln k0.30.81.5-1.2-1.21.00.81.10.70.6-1.2-0.6-0.7-0.7-0.50.91.00.8-0.80.81.00.7-1.0-1.11.01.00.7-0.4-0.7
Indifference point function log k0.30.81.5-1.2-1.21.00.81.10.70.6-1.2-0.6-0.7-0.7-0.50.91.00.8-0.80.81.00.7-1.0-1.11.01.00.7-0.4-0.7
Patch foraging total patch changes 0 sec0.00.00.20.00.0-0.1-0.20.2-0.1-0.2-0.20.30.20.20.30.00.1-0.00.0-0.00.1-0.1-0.2-0.20.20.20.10.5-0.1
Patch foraging total patch changes 12 sec0.81.11.7-1.1-1.11.11.11.11.21.2-0.9-1.2-1.1-1.1-1.31.11.01.1-1.11.11.01.1-0.9-0.90.90.91.2-0.70.4
Patch foraging total patch changes 18 sec0.51.21.8-1.0-1.01.10.91.31.11.1-1.2-1.1-1.1-1.1-1.11.21.21.2-1.21.21.21.2-1.2-1.21.21.21.3-0.5-0.3
Patch foraging total patch changes 24 sec0.31.01.5-0.8-0.80.90.61.21.01.0-1.1-1.0-0.8-0.8-0.91.01.21.0-1.01.01.11.0-1.1-1.11.11.11.2-1.1-0.6
Patch foraging total patch changes 6 sec0.20.31.01.01.0-0.6-0.7-0.5-0.5-0.50.60.70.70.70.5-0.6-0.4-0.60.6-0.6-0.6-0.60.50.6-0.6-0.5-0.40.1-0.1
Patch foraging time to switch 0 sec0.10.51.51.01.0-1.0-0.9-0.7-0.7-0.90.60.60.60.60.8-0.5-1.1-0.50.5-0.4-0.3-0.40.30.2-0.2-0.2-0.61.20.0
Patch foraging water rate 0 sec0.93.55.0-2.2-2.22.01.91.91.91.9-2.0-1.9-1.9-1.9-1.91.92.01.9-1.91.81.81.8-1.8-1.81.81.81.8-1.4-0.8
Patch foraging water rate 12 sec1.24.76.3-2.5-2.52.22.32.22.12.0-2.4-2.0-2.3-2.3-1.92.22.32.2-2.22.12.22.1-2.2-2.32.22.21.9-1.3-1.9
Patch foraging water rate 18 sec2.45.57.3-2.5-2.52.42.52.52.42.4-2.5-2.3-2.3-2.3-2.32.42.72.4-2.42.32.32.3-2.3-2.32.32.32.3-1.6-1.4
Patch foraging water rate 24 sec2.73.95.5-2.3-2.31.92.02.02.02.0-2.0-2.1-2.0-2.0-1.92.01.92.0-2.02.02.02.0-2.0-2.02.02.01.9-1.4-0.7
Patch foraging water rate 6 sec5.07.49.2-3.0-3.02.72.73.02.72.6-3.0-2.7-2.7-2.7-2.52.82.82.8-2.82.82.92.7-2.9-2.92.92.92.7-1.5-1.3
Seeking ratio, delayed vs. immediate footshock0.20.31.5-0.4-0.40.40.60.50.40.4-0.7-0.4-0.4-0.4-0.30.60.50.6-0.50.50.60.5-0.7-0.70.70.70.50.2-1.2
Distance traveled before self-admin2.04.37.6-1.5-1.51.91.72.21.91.8-2.3-2.0-2.1-2.1-1.72.21.82.2-2.22.22.32.2-2.4-2.42.42.41.9-1.2-2.8
Distance traveled after self-admin1.52.63.3-1.3-1.31.61.61.71.61.5-1.8-1.4-1.7-1.7-1.41.71.51.7-1.71.71.81.7-1.8-1.81.81.81.6-0.3-1.6
Extensor digitorum longus weight0.21.01.4-1.1-1.10.91.11.10.90.8-1.2-0.8-0.9-0.9-0.81.10.91.0-1.01.01.11.0-1.1-1.21.21.10.8-0.4-0.6
Bone: elastic displacement0.00.11.00.30.30.10.00.1-0.0-0.0-0.10.30.10.10.1-0.10.3-0.10.1-0.1-0.1-0.10.10.1-0.1-0.1-0.1-0.1-1.0
Bone: elastic work0.20.21.0-0.5-0.50.70.60.60.40.4-0.6-0.2-0.2-0.2-0.30.31.00.3-0.30.20.30.2-0.3-0.30.30.30.3-0.8-0.9
Bone: endosteal estimation0.20.63.2-0.8-0.80.70.60.40.91.0-0.3-1.1-0.9-0.9-1.00.60.50.6-0.60.70.40.7-0.3-0.30.30.30.6-1.8-0.0
Bone: endosteal perimeter0.30.82.0-1.1-1.10.80.90.41.11.2-0.2-1.4-1.2-1.2-1.30.80.30.9-0.90.90.61.0-0.5-0.40.40.50.8-0.91.0
Epididymis fat weight5.025.228.64.84.8-5.3-5.2-5.3-5.2-5.25.25.15.15.15.1-5.2-5.3-5.15.1-5.0-5.0-5.05.04.9-4.9-4.9-4.94.73.9
Delta time in closed arm before/after self-admin1.91.82.51.31.3-1.3-1.3-1.4-1.3-1.21.61.41.31.31.2-1.4-1.4-1.41.4-1.4-1.5-1.41.51.5-1.5-1.5-1.40.40.6
Delta time in open arm before/after self-admin2.02.43.1-1.5-1.51.61.51.71.51.5-1.7-1.5-1.5-1.5-1.41.61.61.6-1.61.61.61.5-1.7-1.71.71.71.6-0.8-0.9
Diff in mean of infusions in LGA sessions9.016.219.83.93.9-4.4-4.4-4.4-4.2-4.14.43.94.14.14.0-4.2-4.4-4.24.2-4.0-4.1-4.04.14.1-4.1-4.1-4.11.72.2
Delay discount exponential model param0.40.50.9-0.6-0.60.50.50.80.60.5-0.9-0.6-0.6-0.6-0.40.80.50.7-0.80.80.90.7-0.9-1.01.00.90.7-0.1-0.6
Extinction: sum of active levers before priming0.20.43.60.20.2-0.4-0.3-0.2-0.5-0.7-0.40.30.30.30.80.0-0.4-0.10.00.00.3-0.0-0.4-0.60.50.5-0.41.9-1.4
Active lever presses in extinction session 60.10.11.00.10.1-0.2-0.20.0-0.1-0.2-0.20.1-0.2-0.20.20.2-0.30.1-0.10.20.30.2-0.3-0.40.40.4-0.11.0-0.3
Bone: final force3.76.18.3-2.9-2.92.32.42.62.62.6-2.3-2.9-2.5-2.5-2.62.52.52.5-2.52.52.42.5-2.4-2.32.32.32.6-2.2-0.1
Bone: final moment3.86.28.6-2.9-2.92.42.52.62.62.6-2.4-2.8-2.6-2.6-2.62.52.52.5-2.52.52.42.5-2.4-2.32.32.42.6-2.1-0.5
Food consumed during 24 hour testing period0.10.31.4-0.5-0.50.60.50.50.50.6-0.5-0.6-0.4-0.4-0.50.40.80.4-0.40.40.40.4-0.4-0.40.40.40.4-1.2-0.4
Glucose0.20.41.2-0.7-0.70.61.10.50.70.8-0.4-0.5-0.7-0.7-0.80.60.30.6-0.60.60.50.6-0.4-0.40.40.40.50.60.6
Heart weight0.91.43.0-1.5-1.51.71.71.21.21.2-1.3-0.9-1.2-1.2-1.11.01.51.0-1.00.90.90.8-0.9-0.80.80.80.8-1.4-1.7
Delay discount hyperbolic model param0.30.40.8-0.5-0.50.50.50.70.50.4-0.9-0.5-0.5-0.5-0.30.70.50.7-0.70.70.80.7-0.9-0.90.90.90.60.0-0.7
Intermittent access intake day 1-15 change1.68.611.4-2.8-2.82.92.93.02.92.7-3.2-2.8-3.1-3.1-2.63.03.13.0-3.02.93.12.9-3.1-3.13.13.12.7-1.6-3.4
Intermittent access intake escalation1.47.69.3-2.6-2.62.72.72.92.72.6-3.0-2.7-2.9-2.9-2.52.82.92.8-2.82.82.92.8-2.9-2.92.92.92.6-1.6-3.0
Intermittent access intake escalation 23.25.47.1-1.8-1.82.12.02.42.32.1-2.6-2.4-2.2-2.2-2.02.52.22.5-2.52.52.62.5-2.6-2.72.72.62.3-1.3-2.4
Intermitt. access day 1 inactive lever presses0.11.42.01.01.0-1.0-1.0-1.3-1.2-1.21.21.41.01.01.2-1.3-1.0-1.31.3-1.4-1.3-1.41.31.3-1.3-1.4-1.40.6-0.2
Intermitt. access day 15 inactive lever presses0.00.00.20.20.2-0.2-0.3-0.0-0.2-0.30.00.20.10.10.3-0.1-0.2-0.10.1-0.1-0.1-0.10.0-0.0-0.0-0.0-0.2-0.3-0.5
Intermitt. access escalation Index0.10.34.3-0.3-0.30.10.1-0.10.40.60.5-0.3-0.2-0.2-0.8-0.10.00.10.00.0-0.30.10.40.5-0.5-0.40.4-0.72.1
Intermittent access day 1 total infusions0.10.40.80.70.7-0.5-0.6-0.6-0.6-0.70.40.60.60.60.7-0.5-0.6-0.60.6-0.6-0.5-0.60.50.4-0.4-0.5-0.9-0.5-0.7
Intermittent access day 15 total infusions1.02.46.8-1.4-1.41.61.41.61.51.4-1.7-1.4-1.7-1.7-1.31.51.71.5-1.51.41.51.4-1.5-1.51.51.51.1-1.8-2.6
Intermittent access terminal intake (last 3 days)2.03.58.6-1.6-1.61.91.71.91.81.7-2.0-1.7-1.9-1.9-1.61.91.81.8-1.81.81.91.8-1.9-1.91.91.91.4-2.1-2.9
Intermittent access total infusions0.91.16.5-0.9-0.91.11.00.90.80.8-1.1-0.7-1.1-1.1-0.70.81.10.8-0.80.70.80.7-0.8-0.90.90.80.4-1.7-2.6
Intermittent access day 1 locomotion1.32.43.91.61.6-1.6-1.7-1.5-1.8-1.91.31.91.51.52.0-1.6-1.6-1.61.6-1.6-1.4-1.61.31.2-1.2-1.3-1.81.0-0.8
Intermittent access day 15 total locomotion0.20.75.8-0.5-0.50.80.80.90.50.3-1.2-0.4-0.8-0.8-0.20.70.80.6-0.70.60.80.6-0.9-1.01.00.90.4-0.2-2.4
Intermittent access total locomotion0.20.23.5-0.2-0.20.20.10.3-0.0-0.2-0.40.1-0.5-0.50.20.10.20.1-0.10.10.30.1-0.3-0.40.40.3-0.1-0.2-1.9
Intermittent access standard deviation0.94.920.5-1.8-1.82.01.92.41.71.4-2.8-1.6-2.1-2.1-1.22.22.22.1-2.12.02.42.0-2.5-2.72.62.61.8-0.8-4.5
Left kidney weight0.21.72.5-1.4-1.41.51.61.31.41.4-1.2-1.3-1.5-1.5-1.41.31.51.3-1.31.31.21.2-1.2-1.11.11.11.3-0.9-0.7
Right kidney weight0.85.37.0-2.5-2.52.52.72.42.32.4-2.4-2.3-2.5-2.5-2.32.32.62.3-2.32.22.22.2-2.2-2.22.22.22.1-1.9-1.9
Cocaine induced anxiety0.20.50.80.70.7-0.7-0.7-0.9-0.5-0.50.90.50.50.50.4-0.7-0.7-0.70.7-0.6-0.8-0.60.80.8-0.8-0.8-0.70.30.4
Post-drug Anxiety0.60.70.8-0.7-0.70.80.70.80.90.8-0.8-0.8-0.9-0.9-0.80.90.80.9-0.90.90.80.9-0.8-0.80.80.80.9-0.5-0.6
Baseline Anxiety1.62.73.7-1.6-1.61.71.71.91.51.4-1.9-1.5-1.6-1.6-1.41.71.61.7-1.71.71.81.6-1.9-1.91.91.91.7-1.0-1.2
Tail length0.63.35.8-2.3-2.32.12.41.72.02.1-1.5-2.0-2.1-2.1-2.21.71.91.8-1.71.71.51.7-1.4-1.31.31.31.7-1.5-0.3
Length with tail0.41.93.1-1.6-1.61.61.71.21.61.7-1.1-1.5-1.8-1.8-1.71.31.31.4-1.41.41.21.4-1.1-1.01.01.01.3-1.3-0.6
Length without tail0.42.33.2-1.5-1.51.61.61.51.71.7-1.4-1.5-1.8-1.8-1.71.51.61.5-1.51.51.41.5-1.3-1.31.31.31.4-1.5-1.2
Times rat made contact with spout4.95.67.22.62.6-2.7-2.6-2.4-2.5-2.52.42.42.62.62.5-2.4-2.3-2.42.4-2.4-2.3-2.42.22.2-2.2-2.2-2.31.60.9
Lifetime Intake0.60.85.8-0.6-0.60.90.70.80.60.6-1.0-0.6-0.9-0.9-0.50.70.80.7-0.70.70.80.6-0.8-0.80.80.80.3-1.4-2.4
Liver weight, left0.71.21.8-1.2-1.21.01.31.10.90.8-1.3-0.8-1.0-1.0-0.71.11.01.1-1.11.01.21.0-1.3-1.31.31.31.00.5-1.2
Liver weight, right0.00.10.9-0.1-0.1-0.10.1-0.1-0.2-0.30.10.3-0.0-0.00.3-0.20.0-0.20.2-0.2-0.2-0.20.10.1-0.1-0.1-0.11.0-0.4
Locomotor activity2.74.36.0-2.1-2.12.22.12.32.01.9-2.4-2.0-1.8-1.8-1.82.22.42.1-2.12.12.22.0-2.3-2.32.22.32.1-1.2-1.3
Locomotor testing distance4.110.012.3-3.4-3.43.43.33.43.13.1-3.5-3.2-3.0-3.0-2.93.33.53.2-3.33.23.33.1-3.3-3.33.33.33.1-2.2-1.7
Locomotor testing rearing3.011.014.2-3.4-3.43.33.33.73.23.0-3.8-3.1-3.2-3.2-2.93.53.53.4-3.43.43.63.3-3.6-3.73.63.63.3-1.6-2.3
Locomotion in novel chamber1.62.22.91.71.7-1.6-1.6-1.4-1.6-1.51.51.51.51.51.5-1.6-1.4-1.61.6-1.6-1.5-1.61.51.5-1.5-1.5-1.30.70.3
Locomotion in novel chamber post-restriction0.41.21.9-1.4-1.41.01.01.31.11.0-1.2-1.0-1.1-1.1-1.01.21.21.1-1.11.11.21.1-1.2-1.21.21.21.1-0.7-0.5
Fecal boli incidents, locomotor time 10.10.30.5-0.6-0.60.40.30.50.50.5-0.6-0.7-0.5-0.5-0.50.60.30.6-0.70.70.70.7-0.7-0.70.70.70.7-0.6-0.1
Change in fecal boli incidents, locomotor task0.00.00.0-0.1-0.1-0.1-0.00.1-0.1-0.2-0.10.10.00.00.20.00.1-0.00.0-0.00.1-0.0-0.1-0.10.10.1-0.1-0.1-0.2
Time >=10cm from walls, locomotor time 10.50.71.1-0.6-0.60.70.61.00.70.6-1.0-0.5-0.7-0.7-0.50.90.70.8-0.90.81.00.8-1.0-1.01.01.00.8-0.3-1.1
Bouts of movement, locomotor time 11.41.83.51.11.1-1.3-1.1-1.5-1.5-1.41.31.41.31.31.5-1.4-1.2-1.41.4-1.4-1.4-1.41.31.3-1.3-1.3-1.41.90.5
Total resting periods, locomotor time 11.21.42.50.90.9-1.1-1.0-1.3-1.2-1.21.21.21.11.11.2-1.3-1.0-1.31.3-1.3-1.2-1.31.21.2-1.2-1.2-1.21.60.7
Rest time, locomotor task time 11.11.82.21.31.3-1.3-1.1-1.4-1.4-1.31.41.31.31.31.3-1.4-1.1-1.41.4-1.4-1.5-1.41.51.5-1.5-1.5-1.31.40.6
Distance moved, locomotor task time 11.03.03.9-1.7-1.71.81.61.81.71.6-2.0-1.5-1.7-1.7-1.51.81.71.8-1.81.71.81.7-1.8-1.91.91.81.5-1.5-1.8
Vertical activity count, locomotor time 10.10.61.0-0.9-0.90.70.70.80.70.7-1.0-0.6-0.7-0.7-0.60.90.70.8-0.90.80.90.8-0.9-1.01.00.90.6-0.2-0.6
Time >=10cm from walls, locomotor time 20.00.10.80.20.2-0.2-0.20.3-0.1-0.3-0.40.20.10.10.30.2-0.10.2-0.20.20.40.2-0.5-0.60.60.50.20.9-0.5
Bouts of movement, locomotor time 20.20.81.31.01.0-0.9-0.7-0.7-1.0-1.00.81.01.11.11.0-0.9-0.6-0.90.9-0.9-0.8-1.00.80.8-0.8-0.8-0.70.80.6
Total resting periods, locomotor time 20.20.81.21.01.0-1.0-0.7-0.8-1.0-1.00.91.01.11.11.0-1.0-0.6-1.01.0-1.0-0.9-1.00.90.9-0.9-0.8-0.80.50.5
Rest time, locomotor task time 20.20.40.70.80.8-0.4-0.5-0.7-0.5-0.40.70.40.50.50.4-0.6-0.3-0.60.6-0.6-0.7-0.60.80.8-0.8-0.8-0.6-0.5-0.7
Distance moved, locomotor task time 20.70.91.7-1.1-1.10.90.91.00.80.7-1.3-0.6-0.9-0.9-0.61.00.91.0-1.00.91.10.9-1.2-1.21.21.20.70.0-0.7
Vertical activity count, locomotor time 20.00.11.0-0.1-0.1-0.1-0.00.1-0.2-0.3-0.30.30.30.30.40.0-0.10.0-0.00.00.2-0.0-0.3-0.30.30.3-0.11.00.1
Light reinforcement 10.10.51.2-1.1-1.10.81.00.50.91.0-0.3-0.9-0.8-0.8-1.10.60.70.6-0.60.60.40.6-0.3-0.20.20.30.7-0.50.9
Light reinforcement 20.20.53.0-1.0-1.00.70.70.30.81.0-0.0-0.9-0.6-0.6-1.10.40.60.5-0.40.50.20.5-0.10.0-0.00.00.5-0.61.7
Bone: marrow area0.20.63.3-0.8-0.80.70.60.40.91.0-0.3-1.2-0.9-0.9-1.10.60.50.7-0.70.70.50.7-0.4-0.30.30.30.6-1.8-0.0
Bone: maximum diameter0.91.73.2-1.8-1.81.11.50.91.41.4-0.9-1.8-1.6-1.6-1.51.30.71.3-1.31.41.21.4-1.1-1.11.11.11.3-0.01.1
Bone: maximum force3.46.78.6-2.9-2.92.52.52.72.72.7-2.6-2.9-2.6-2.6-2.62.72.52.7-2.72.72.62.6-2.6-2.52.52.62.7-2.4-0.6
Bone: maximum moment3.77.09.2-3.0-3.02.62.62.82.72.7-2.7-2.9-2.7-2.7-2.62.72.62.7-2.72.72.72.7-2.7-2.62.62.62.6-2.3-1.0
Mean time between licks in bursts0.00.11.40.10.1-0.2-0.30.0-0.0-0.1-0.0-0.30.20.20.10.1-0.30.1-0.10.20.20.1-0.2-0.20.20.20.30.21.2
Mean num. licks in bursts1.02.63.51.71.7-1.6-1.5-1.6-1.5-1.41.81.71.81.81.4-1.8-1.0-1.71.8-1.8-1.8-1.71.91.9-1.9-1.9-1.60.50.4
Cd content in liver0.00.00.00.10.1-0.2-0.2-0.2-0.2-0.20.10.10.20.20.2-0.20.0-0.20.2-0.2-0.2-0.20.10.1-0.1-0.1-0.10.1-0.2
Co content in liver0.10.11.20.10.10.20.1-0.10.00.10.10.30.10.1-0.1-0.20.3-0.20.2-0.3-0.3-0.30.40.4-0.4-0.4-0.3-1.1-0.2
Cu content in liver0.40.51.1-0.9-0.90.60.70.70.80.9-0.6-0.8-0.8-0.8-0.90.70.90.7-0.70.70.60.7-0.5-0.50.50.50.7-1.10.1
Fe content in liver0.10.11.5-0.5-0.50.50.60.30.30.4-0.2-0.1-0.2-0.2-0.40.10.60.1-0.10.0-0.00.00.00.1-0.1-0.10.0-1.20.1
K content in liver0.30.30.7-0.5-0.50.40.40.40.70.7-0.2-0.7-0.7-0.7-0.80.50.30.6-0.60.60.50.7-0.4-0.30.30.40.6-0.60.6
Mg content in liver0.91.01.8-1.0-1.00.90.81.01.21.2-0.7-1.2-1.2-1.2-1.31.00.71.1-1.11.10.91.2-0.9-0.80.80.91.1-1.10.3
Mn content in liver7.38.212.1-3.1-3.12.92.92.73.33.4-2.4-3.2-3.3-3.3-3.52.92.53.0-3.03.02.73.1-2.5-2.42.42.42.9-2.7-0.1
Na content in liver3.84.35.0-2.2-2.21.92.12.12.22.2-2.0-2.2-2.2-2.2-2.22.21.82.2-2.22.22.12.2-2.1-2.12.12.12.1-1.7-0.4
Rb content in liver0.81.01.5-1.1-1.11.01.10.91.11.2-0.8-1.0-1.1-1.1-1.21.01.01.0-1.01.00.81.0-0.8-0.70.70.71.0-0.9-0.0
Se content in liver0.50.61.31.01.0-1.1-1.2-0.7-0.9-1.10.50.90.80.81.1-0.7-1.0-0.70.7-0.7-0.5-0.70.40.4-0.4-0.4-0.80.8-0.5
Sr content in liver0.50.40.8-0.6-0.60.50.60.70.60.5-0.9-0.5-0.7-0.7-0.40.70.40.7-0.70.70.80.7-0.8-0.90.90.80.6-0.1-0.6
Zn content in liver0.30.30.60.80.8-0.6-0.7-0.5-0.6-0.70.40.70.60.60.7-0.5-0.6-0.50.5-0.5-0.4-0.50.40.4-0.4-0.4-0.60.4-0.6
Bone: minimum diameter0.61.22.2-1.5-1.51.01.11.01.11.1-1.0-1.3-1.2-1.2-1.11.10.81.1-1.11.11.11.2-1.1-1.11.11.11.1-0.10.0
Time in familiar zone, hab. session 10.40.41.20.50.5-0.6-0.9-0.7-0.5-0.40.90.40.50.50.3-0.6-0.6-0.60.6-0.6-0.7-0.50.80.8-0.8-0.8-0.50.11.1
Time in novel zone, hab. session 10.20.22.20.60.6-0.3-0.2-0.1-0.5-0.7-0.20.60.30.30.8-0.2-0.4-0.20.2-0.20.1-0.2-0.2-0.30.20.2-0.20.8-1.5
Total zone transitions, hab. session 11.21.72.0-1.4-1.41.31.11.41.31.2-1.4-1.2-1.4-1.4-1.21.31.31.3-1.31.31.41.3-1.4-1.41.41.41.3-1.2-0.9
Total locomotion distance, hab. session 11.52.13.1-1.7-1.71.71.81.51.51.6-1.4-1.3-1.6-1.6-1.51.41.71.4-1.41.31.31.3-1.2-1.21.21.21.3-1.3-1.4
Locomotion velocity, hab. session 11.21.72.4-1.5-1.51.41.51.31.41.4-1.3-1.2-1.5-1.5-1.41.31.51.3-1.31.21.21.3-1.2-1.11.11.11.2-1.0-0.9
Time in familiar zone, hab. session 22.63.03.81.71.7-1.8-1.8-2.0-1.7-1.61.91.71.71.71.6-1.8-1.6-1.81.8-1.8-1.8-1.71.91.9-1.9-1.9-1.81.21.1
Time in novel zone, hab. session 21.81.92.9-1.2-1.21.31.21.61.31.1-1.6-1.3-1.3-1.3-1.11.51.01.5-1.51.51.61.5-1.7-1.71.71.71.4-0.5-1.1
Total zone transitions, hab. session 21.01.21.8-1.1-1.11.01.11.11.11.0-1.1-1.1-1.3-1.3-1.01.11.01.1-1.11.11.21.1-1.2-1.21.21.21.1-0.7-1.3
Total locomotion distance, hab. session 20.81.12.0-1.4-1.41.21.40.91.11.1-0.9-1.0-1.3-1.3-1.11.01.01.0-1.00.90.91.0-0.8-0.80.80.80.9-0.5-0.9
Locomotion velocity, hab. session 20.60.81.6-1.2-1.21.01.30.80.91.0-0.8-0.8-1.1-1.1-1.00.81.00.8-0.80.80.80.8-0.7-0.70.70.70.8-0.4-0.9
Novel to familiar place preference ratio0.50.73.60.70.7-1.1-1.0-0.6-1.0-1.20.40.90.90.91.2-0.7-1.0-0.70.7-0.7-0.5-0.70.30.3-0.3-0.3-0.71.90.3
Novelty place preference0.60.84.00.90.9-1.1-1.1-0.6-1.1-1.30.40.91.01.01.3-0.7-1.1-0.70.7-0.7-0.4-0.70.30.2-0.2-0.3-0.72.00.1
Time in novel zone, NPP test0.60.74.60.80.8-1.1-1.1-0.5-1.1-1.30.20.90.90.91.4-0.6-1.1-0.60.6-0.6-0.3-0.60.10.0-0.0-0.1-0.62.1-0.2
Total zone transitions, NPP test0.00.10.1-0.3-0.30.00.10.00.20.20.0-0.3-0.4-0.4-0.20.2-0.00.2-0.20.20.20.3-0.2-0.20.20.20.30.30.3
Total locomotion distance, NPP test0.60.91.9-1.4-1.41.01.20.71.01.1-0.6-1.1-1.2-1.2-1.20.80.80.9-0.90.90.70.9-0.6-0.60.60.60.8-0.60.1
Locomotion velocity, NPP test0.60.92.0-1.4-1.41.01.30.71.11.2-0.5-1.1-1.2-1.2-1.30.80.90.9-0.80.90.60.9-0.5-0.50.50.50.8-0.80.5
Intraocular pressure1.32.12.9-1.4-1.41.31.51.71.41.3-1.6-1.5-1.2-1.2-1.31.61.31.5-1.61.61.61.5-1.7-1.61.61.71.60.0-0.5
Delta distance traveled before/after self-admin0.60.71.60.40.4-0.5-0.4-0.9-0.7-0.60.90.80.80.80.5-0.9-0.5-0.90.9-0.9-1.0-0.91.11.1-1.1-1.1-0.80.61.3
Delta ambulatory time before/after self-admin0.10.20.8-0.8-0.80.70.90.40.50.6-0.3-0.3-0.4-0.4-0.60.30.80.3-0.30.20.10.2-0.1-0.00.00.00.3-0.10.7
Parametrial fat weight2.55.912.22.42.4-2.8-2.4-2.6-2.6-2.72.42.42.52.52.6-2.4-2.7-2.42.4-2.3-2.2-2.32.12.1-2.1-2.1-2.33.51.9
Pavlov. Cond. lever latency0.30.40.80.90.9-0.6-0.7-0.6-0.6-0.70.40.80.50.50.8-0.5-0.8-0.50.5-0.4-0.3-0.40.30.2-0.2-0.3-0.50.8-0.6
Pavlov. Cond. magazine entry latency0.00.00.3-0.3-0.3-0.00.10.10.10.1-0.0-0.2-0.0-0.0-0.10.10.10.1-0.10.10.10.1-0.1-0.10.10.10.20.30.5
Pavlov. Cond. change in total contacts1.21.22.2-1.5-1.51.11.11.21.21.3-0.9-1.3-1.2-1.2-1.31.11.11.1-1.11.11.01.1-0.9-0.90.90.91.1-1.10.2
Pavlov. Cond. index score0.40.51.0-1.0-1.00.60.70.80.70.7-0.6-0.9-0.6-0.6-0.70.70.80.7-0.70.70.60.7-0.6-0.60.60.60.8-0.30.5
Pavlov. Cond. latency score0.30.40.9-0.9-0.90.60.60.70.60.7-0.4-0.8-0.5-0.5-0.70.50.70.6-0.50.50.50.5-0.4-0.40.40.40.6-0.40.7
Pavlov. Cond. lever contacts0.60.71.3-1.1-1.10.80.90.90.91.0-0.7-1.0-0.8-0.8-1.00.80.90.8-0.80.80.70.8-0.7-0.60.60.70.9-0.80.4
Pavlov. Cond. magazine entry number0.30.40.80.90.9-0.7-0.8-0.7-0.7-0.70.50.70.60.60.7-0.6-0.8-0.60.6-0.6-0.6-0.60.60.5-0.5-0.6-0.70.4-0.3
Pavlov. Cond. intertrial magazine entries0.81.05.0-0.4-0.41.20.71.01.01.1-0.9-0.7-1.0-1.0-1.00.81.30.8-0.80.70.70.7-0.6-0.60.60.60.8-2.2-1.8
Pavlov. Cond. lever-magazine prob. diff.0.40.50.9-1.0-1.00.60.70.80.70.7-0.6-0.9-0.7-0.7-0.80.70.70.7-0.70.70.70.7-0.7-0.60.60.70.8-0.30.5
Pavlov. Cond. response bias0.40.50.8-0.9-0.90.70.80.70.70.8-0.5-0.8-0.7-0.7-0.80.70.80.7-0.70.70.60.7-0.6-0.50.50.50.7-0.70.1
Pavlov. Cond. lever latency0.60.91.70.80.8-0.5-0.4-1.0-0.8-0.71.00.90.90.90.7-1.1-0.3-1.11.1-1.1-1.2-1.21.31.3-1.3-1.3-1.00.20.6
Pavlov. Cond. magazine entry latency1.92.64.41.61.6-2.1-2.0-1.7-1.7-1.71.81.51.61.61.6-1.6-2.0-1.61.6-1.5-1.5-1.41.51.5-1.4-1.5-1.61.41.4
Pavlov. Cond. change in total contacts0.10.30.6-0.6-0.60.10.10.50.40.3-0.5-0.5-0.6-0.6-0.30.60.00.6-0.60.70.70.7-0.8-0.80.80.80.50.30.2
Pavlov. Cond. index score0.30.41.20.60.6-1.1-1.1-0.6-0.7-0.80.60.60.60.60.8-0.5-1.1-0.50.5-0.4-0.4-0.40.30.3-0.3-0.3-0.60.90.6
Pavlov. Cond. latency score0.50.81.90.90.9-1.4-1.3-1.0-1.0-1.11.00.80.80.81.0-0.8-1.4-0.80.8-0.7-0.7-0.70.70.6-0.6-0.6-0.81.10.9
Pavlov. Cond. lever contacts0.50.81.4-0.7-0.70.50.40.90.80.6-0.9-0.8-0.9-0.9-0.61.00.31.0-1.01.01.11.1-1.2-1.21.21.20.8-0.2-0.5
Pavlov. Cond. magazine entry number2.63.35.6-1.8-1.82.42.31.91.81.9-2.0-1.6-1.8-1.8-1.81.72.31.7-1.71.61.61.5-1.6-1.61.61.61.6-1.8-2.2
Pavlov. Cond. intertrial magazine entries1.53.35.5-2.0-2.02.32.21.72.12.3-1.5-1.9-1.9-1.9-2.31.72.21.7-1.71.61.41.6-1.2-1.21.21.21.8-2.3-0.6
Pavlov. Cond. lever-magazine prob. diff.0.40.61.70.80.8-1.2-1.3-0.7-0.8-0.90.70.70.70.70.9-0.6-1.2-0.60.6-0.5-0.5-0.50.40.4-0.4-0.4-0.70.90.7
Pavlov. Cond. response bias0.10.20.6-0.3-0.3-0.2-0.10.30.2-0.0-0.4-0.3-0.3-0.30.00.5-0.30.4-0.50.50.70.6-0.7-0.80.80.70.30.6-0.0
Time in closed arm before self-admin0.10.10.6-0.2-0.20.30.30.10.10.20.2-0.0-0.0-0.0-0.2-0.20.3-0.20.2-0.2-0.3-0.20.40.4-0.4-0.4-0.0-0.80.8
Time in closed arm after self-admin0.60.61.30.50.5-0.6-0.4-0.8-0.6-0.51.10.70.60.60.4-0.9-0.6-0.90.9-0.9-1.0-0.91.11.2-1.1-1.1-0.8-0.11.1
Time in open arm before self-admin4.25.16.82.52.5-2.5-2.6-2.4-2.3-2.42.42.22.32.32.3-2.3-2.5-2.32.2-2.2-2.2-2.12.12.1-2.1-2.1-2.22.20.8
Time in open arm after self-admin0.10.11.00.40.4-0.3-0.5-0.0-0.3-0.5-0.30.30.30.30.60.0-0.3-0.0-0.00.00.2-0.0-0.3-0.40.40.4-0.00.8-1.0
Bone: periosteal estimation1.63.95.8-2.3-2.31.91.91.82.12.1-1.7-2.4-2.2-2.2-2.12.01.62.0-2.02.11.92.1-1.8-1.81.81.82.0-1.8-0.3
Bone: periosteal perimeter1.52.94.7-2.0-2.01.61.71.41.81.8-1.4-2.2-2.0-2.0-1.91.81.21.8-1.81.81.71.9-1.6-1.61.61.61.7-1.00.3
Bone: post-yield work1.01.72.1-1.4-1.41.31.21.31.21.2-1.4-1.4-1.4-1.4-1.11.31.11.3-1.31.31.31.3-1.3-1.41.41.31.1-1.3-1.5
Progressive ratio test 1 active lever presses1.01.83.4-1.2-1.21.51.41.31.21.2-1.5-1.2-1.3-1.3-1.11.41.21.3-1.41.31.41.3-1.4-1.41.41.41.0-1.1-1.8
Progressive ratio test 1 breakpoint1.01.73.6-1.1-1.11.51.41.31.21.1-1.5-1.2-1.3-1.3-1.11.41.21.3-1.31.31.41.3-1.4-1.41.41.41.0-1.1-1.9
Progressive ratio test 1 inactive lever presses0.00.10.70.40.40.0-0.10.30.0-0.1-0.3-0.1-0.0-0.00.10.2-0.10.2-0.20.20.30.1-0.3-0.30.30.40.1-0.2-0.8
Progressive ratio test 2 active lever presses0.40.52.1-0.3-0.30.70.60.80.80.8-0.6-0.8-0.8-0.8-0.80.70.50.7-0.70.70.60.7-0.6-0.60.60.60.7-1.5-1.0
Progressive ratio test 2 breakpoint0.50.62.1-0.3-0.30.70.70.90.80.8-0.6-0.8-0.8-0.8-0.80.70.60.8-0.70.70.70.8-0.7-0.60.60.70.8-1.4-1.1
Progressive ratio test 2 inactive lever presses0.20.83.1-0.7-0.71.00.91.00.91.0-0.8-0.7-1.0-1.0-1.00.80.80.8-0.80.80.70.8-0.7-0.60.60.70.8-1.8-1.1
Incentive Sensitization - Responses0.10.22.00.20.20.20.20.10.50.60.3-0.4-0.4-0.4-0.70.1-0.10.2-0.10.2-0.10.20.20.3-0.3-0.30.3-1.40.2
Incentive Sensitization - Breakpoint0.10.22.10.20.20.20.20.20.50.60.2-0.5-0.4-0.4-0.80.20.00.2-0.20.2-0.00.30.10.2-0.2-0.20.3-1.40.2
Sum of active levers in priming session hrs 5-62.82.64.12.02.0-1.8-1.9-1.7-1.8-2.01.31.71.71.72.0-1.5-1.7-1.61.5-1.5-1.3-1.51.21.1-1.1-1.2-1.71.0-1.5
Progressive ratio0.20.60.9-0.9-0.90.50.80.80.80.7-0.8-0.8-0.9-0.9-0.70.90.50.9-0.90.90.90.9-0.9-0.90.90.90.80.5-0.1
Food seeking constrained by brief footshock0.10.11.00.40.4-0.3-0.40.10.20.30.3-0.4-0.1-0.1-0.40.1-0.20.2-0.20.30.10.3-0.00.0-0.00.00.2-0.61.0
Seeking ratio, punishment vs. effort0.20.51.11.01.0-0.7-1.0-0.5-0.6-0.50.70.60.80.80.5-0.7-0.4-0.70.7-0.7-0.7-0.70.70.8-0.8-0.7-0.6-1.00.5
Retroperitoneal fat weight3.716.418.53.73.7-4.3-4.0-4.2-4.2-4.24.14.14.24.24.2-4.1-4.1-4.14.1-4.1-4.0-4.03.93.9-3.9-3.9-4.04.13.6
Reaction time number correct0.10.51.3-0.4-0.40.20.20.80.30.1-1.0-0.4-0.3-0.3-0.00.70.40.6-0.70.70.90.7-1.0-1.11.11.10.71.1-0.5
Reaction time mean minus median0.42.53.21.71.7-1.6-1.7-1.5-1.7-1.71.51.71.81.81.7-1.6-1.5-1.61.6-1.6-1.6-1.61.51.5-1.5-1.5-1.41.40.9
Reaction time mean minus median AUC0.74.55.22.12.1-2.1-2.1-2.1-2.2-2.12.22.22.32.32.1-2.2-1.9-2.22.2-2.2-2.2-2.22.22.2-2.2-2.2-2.01.81.3
Reaction time num false alarms1.32.23.4-1.7-1.71.91.81.41.61.6-1.5-1.4-1.6-1.6-1.61.51.41.5-1.51.51.41.5-1.3-1.31.31.31.4-1.2-0.7
Reaction time num false alarms AUC1.22.73.9-1.9-1.92.02.01.61.71.7-1.7-1.6-1.7-1.7-1.71.71.61.7-1.71.61.61.6-1.5-1.51.51.51.5-1.2-0.7
Reaction time trials correct on left0.10.51.3-0.4-0.40.20.20.80.30.1-1.0-0.4-0.3-0.3-0.00.70.40.6-0.70.70.90.7-1.0-1.11.11.10.71.1-0.5
Reaction time trials on left0.10.51.4-0.4-0.40.20.20.80.30.1-0.9-0.4-0.3-0.3-0.00.70.40.6-0.70.70.90.7-1.0-1.11.11.10.71.2-0.5
Reaction time mean1.22.63.21.61.6-1.5-1.5-1.6-1.6-1.51.71.71.51.51.5-1.7-1.4-1.71.7-1.7-1.8-1.71.81.8-1.8-1.8-1.61.20.9
Reaction time mean AUC1.43.54.31.81.8-1.7-1.7-1.9-1.9-1.82.02.01.81.81.7-2.0-1.7-2.02.0-2.0-2.0-2.02.12.1-2.1-2.1-1.91.31.0
Median of all reaction times1.01.52.21.11.1-1.1-1.0-1.3-1.1-1.01.41.31.11.11.0-1.3-1.1-1.31.3-1.3-1.4-1.31.51.5-1.5-1.5-1.30.70.8
Reaction time omissions1.11.83.61.41.4-1.4-1.3-1.3-1.3-1.31.51.31.31.31.3-1.3-1.6-1.31.3-1.2-1.3-1.21.21.3-1.3-1.2-1.11.91.6
Reaction time false alarm rate0.91.23.0-1.4-1.41.51.50.91.21.4-0.8-1.1-1.2-1.2-1.41.01.11.0-1.00.90.70.9-0.6-0.60.60.60.8-1.7-0.3
Reaction time premature initiation rate0.30.51.00.70.7-0.7-0.8-0.5-0.7-0.70.60.81.01.00.7-0.7-0.4-0.70.7-0.7-0.7-0.80.60.7-0.7-0.6-0.50.10.5
Reaction time premature initiations0.00.10.50.40.4-0.4-0.6-0.0-0.4-0.50.00.50.70.70.6-0.3-0.0-0.30.3-0.3-0.1-0.30.00.0-0.0-0.0-0.00.50.1
Std. dev. reaction times0.82.53.11.61.6-1.6-1.7-1.5-1.7-1.71.51.81.71.71.7-1.6-1.5-1.61.6-1.6-1.6-1.61.51.5-1.5-1.5-1.51.40.8
Reaction time trials completed0.10.51.4-0.4-0.40.20.20.80.30.1-0.9-0.4-0.3-0.3-0.00.70.40.6-0.70.70.90.7-1.0-1.11.11.10.71.2-0.5
Reaction time trials AUC0.31.01.9-0.8-0.80.60.71.10.70.5-1.3-0.8-0.7-0.7-0.51.10.81.0-1.11.11.31.0-1.3-1.41.41.41.00.8-0.6
Run reversals in cocaine runway, females0.00.00.2-0.1-0.10.30.10.30.00.0-0.30.10.20.20.10.10.50.0-0.0-0.00.1-0.1-0.1-0.10.10.10.1-0.2-0.1
Run reversals in cocaine runway, males0.91.02.60.80.8-0.7-0.9-1.2-0.6-0.31.40.50.60.60.2-0.9-0.8-0.90.9-0.8-1.2-0.81.31.4-1.4-1.4-0.9-0.91.6
Latency to leave start box in cocaine runway0.71.01.70.50.5-0.8-0.7-1.3-0.8-0.81.20.90.80.80.7-1.1-0.9-1.01.1-1.0-1.2-1.01.31.3-1.3-1.3-1.20.81.0
Latency to leave start box in cocaine runway, F0.60.81.50.50.5-0.9-0.8-1.1-0.8-0.71.10.70.70.70.6-0.9-1.0-0.90.9-0.9-1.0-0.81.11.1-1.1-1.1-1.00.91.2
Latency to leave start box in cocaine runway, M0.60.51.00.50.5-0.5-0.4-0.9-0.6-0.60.80.80.60.60.5-0.8-0.4-0.80.8-0.9-0.9-0.91.01.0-1.0-1.0-0.90.10.2
Std. dev. time between licks in bursts1.22.22.6-1.4-1.41.51.31.61.51.5-1.5-1.6-1.6-1.6-1.51.61.11.6-1.61.61.61.6-1.6-1.61.61.61.6-1.1-0.4
Total sessions with >9 infusions0.30.45.7-0.3-0.30.50.50.40.20.1-0.8-0.1-0.6-0.60.00.50.40.4-0.40.40.60.3-0.6-0.70.70.70.00.0-2.4
Short access day 1 total inactive lever presses0.30.61.00.50.5-0.6-0.7-0.7-0.9-0.90.61.00.60.60.9-0.8-0.7-0.90.9-0.9-0.8-0.90.80.7-0.7-0.8-0.90.3-0.2
Short access day 10 total inactive lever presses0.10.50.80.60.6-0.7-0.7-0.7-0.7-0.70.70.70.60.60.7-0.7-0.5-0.70.7-0.8-0.7-0.70.70.7-0.7-0.7-0.60.90.3
Short access day 1 total infusions0.10.31.8-0.2-0.20.40.30.50.30.3-0.6-0.3-0.5-0.5-0.20.50.30.5-0.50.50.60.5-0.6-0.60.60.60.4-0.5-1.3
Short access day 10 total infusions0.71.18.6-0.7-0.71.31.10.90.70.7-1.2-0.5-1.1-1.1-0.60.81.20.7-0.80.70.80.6-0.8-0.90.90.80.3-1.2-2.9
Short access total infusions0.10.12.50.20.20.2-0.00.1-0.0-0.1-0.40.0-0.1-0.10.20.2-0.00.1-0.10.10.30.1-0.3-0.30.30.3-0.2-0.3-1.6
Short access day 1 locomotion0.20.35.30.30.3-0.1-0.10.1-0.4-0.6-0.30.70.00.00.7-0.20.0-0.20.2-0.30.0-0.3-0.1-0.20.20.1-0.40.3-2.3
Short access day 10 total locomotion0.00.20.50.00.0-0.1-0.1-0.4-0.4-0.40.30.70.10.10.5-0.5-0.1-0.50.5-0.6-0.5-0.50.50.4-0.5-0.5-0.70.1-0.7
Short access total locomotion0.20.33.20.30.3-0.2-0.2-0.3-0.6-0.70.00.80.10.10.8-0.4-0.3-0.50.4-0.5-0.3-0.50.20.1-0.1-0.2-0.70.6-1.8
One hour access (0.3 mA shock)1.72.06.8-1.4-1.41.61.41.21.31.3-1.4-1.3-1.7-1.7-1.31.31.41.2-1.21.21.21.2-1.2-1.21.21.10.9-2.1-2.6
Compulsive drug intake5.48.010.82.32.3-2.6-2.7-2.9-3.0-3.02.93.32.42.43.0-3.2-2.4-3.23.2-3.3-3.1-3.23.13.0-3.0-3.1-2.92.20.3
One hour access (shock baseline)2.46.39.2-2.1-2.12.52.32.52.62.5-2.5-2.7-2.5-2.5-2.52.62.22.6-2.62.62.62.6-2.5-2.52.52.52.2-3.0-2.2
Social response proportion2.12.65.71.61.6-1.7-1.7-1.7-1.4-1.32.11.31.51.51.1-1.7-1.7-1.61.6-1.5-1.7-1.51.81.9-1.9-1.8-1.20.72.4
Social responses0.70.92.0-1.0-1.00.90.80.81.21.3-0.5-1.2-0.9-0.9-1.40.90.91.0-0.90.90.71.0-0.6-0.50.50.61.1-1.01.2
Social time0.50.71.00.60.6-0.7-0.8-0.9-0.9-0.80.90.90.60.60.8-0.9-0.9-0.90.9-0.9-0.9-0.90.90.9-0.9-0.9-0.81.00.6
Soleus weight0.00.10.50.20.20.10.20.20.20.2-0.3-0.1-0.1-0.1-0.20.20.40.2-0.20.20.20.2-0.2-0.20.20.20.2-0.1-0.7
Bone: stiffness4.07.39.2-2.8-2.82.52.42.82.82.8-2.6-3.0-2.8-2.8-2.82.82.52.8-2.82.92.82.9-2.7-2.72.72.72.8-2.4-0.7
Tibialis anterior weight0.20.61.00.90.9-0.8-0.7-0.7-0.9-0.90.70.91.01.00.9-0.8-0.6-0.90.9-0.9-0.8-0.90.80.8-0.8-0.8-0.90.30.1
Time to tail flick, vehicle, before self-admin2.43.05.71.91.9-2.1-2.4-2.1-1.8-1.82.01.51.61.61.7-1.7-2.3-1.71.7-1.5-1.6-1.51.61.5-1.5-1.5-1.61.31.0
Time to tail flick, vehicle, after self-admin1.93.95.02.12.1-2.2-2.2-2.0-2.1-2.22.02.12.22.22.2-2.0-2.1-2.02.0-1.9-1.8-1.91.81.7-1.7-1.7-2.01.70.7
Time to tail flick, test, before self-admin0.10.21.80.00.00.30.1-0.10.10.30.30.30.00.0-0.3-0.20.4-0.20.2-0.3-0.4-0.30.50.5-0.5-0.5-0.1-0.61.4
Time to tail flick, test, after self-admin0.10.11.0-0.2-0.20.00.00.0-0.2-0.2-0.20.20.10.10.3-0.00.1-0.10.1-0.10.0-0.1-0.1-0.10.10.1-0.11.00.6
Delta time to tail flick, vehicle, before/after SA0.80.81.5-1.1-1.11.01.21.20.90.9-1.1-0.7-0.7-0.7-0.90.91.20.9-0.90.90.90.9-0.9-0.90.90.90.8-0.4-0.2
Delta time to tail flick, test, before/after SA0.50.63.40.50.5-0.9-0.7-0.8-0.9-1.10.50.70.80.81.1-0.7-0.9-0.70.7-0.7-0.5-0.70.40.3-0.3-0.4-0.81.8-0.1
Tibia length4.813.220.7-4.0-4.04.03.93.64.14.4-3.1-4.1-4.0-4.0-4.43.54.13.6-3.63.53.13.6-2.9-2.82.82.83.4-4.6-1.1
Ambulatory time before self-admin1.33.97.1-1.3-1.31.71.52.11.71.5-2.3-1.8-1.9-1.9-1.42.11.62.1-2.12.12.32.1-2.4-2.42.42.41.8-0.7-2.7
Ambulatory time after self-admin0.71.21.7-0.8-0.81.11.21.21.11.0-1.2-0.9-1.1-1.1-1.01.11.11.1-1.11.11.21.1-1.2-1.21.21.21.0-0.3-1.3
Bone: tissue strength1.11.11.9-1.2-1.21.21.01.21.00.9-1.3-0.9-1.0-1.0-0.81.01.31.0-1.00.91.00.9-1.1-1.11.11.10.9-1.1-1.4
Total heroin consumption1.82.14.42.12.1-1.8-1.9-1.2-1.7-1.91.01.61.51.52.0-1.2-1.8-1.31.2-1.1-0.9-1.10.70.6-0.6-0.6-1.31.3-1.8
Bone: trabecular number0.10.20.8-0.8-0.80.70.80.50.40.5-0.4-0.3-0.2-0.2-0.40.30.60.3-0.30.20.20.1-0.2-0.10.10.10.4-0.90.5
Bone: trabecular spacing0.50.81.91.11.1-1.3-1.4-0.9-0.8-0.91.00.60.80.80.8-0.7-1.3-0.70.7-0.6-0.6-0.50.60.6-0.6-0.6-0.61.20.9
Bone: trabecular thickness1.11.63.0-1.5-1.51.51.71.31.31.3-1.3-1.2-1.3-1.3-1.31.21.51.2-1.21.11.11.1-1.1-1.11.11.11.1-0.9-1.0
Bone: trabecular tissue density0.20.40.7-0.3-0.30.40.30.60.60.5-0.6-0.6-0.8-0.8-0.50.70.20.7-0.70.80.80.8-0.8-0.80.80.80.6-0.5-0.7
Water consumed over 24 hours0.10.20.7-0.6-0.60.30.30.50.50.4-0.4-0.5-0.4-0.4-0.40.50.50.5-0.50.50.50.5-0.5-0.50.50.50.5-0.80.1
Number of responses in last shaping day1.11.42.0-1.1-1.11.31.21.31.21.2-1.2-1.1-1.2-1.2-1.21.21.41.2-1.11.11.11.1-1.1-1.11.11.11.2-1.3-1.1