Hub : Genes

Htr7

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Htr7 0.07 0.05 2.5e-04 0.01 0 0.02 -0 1.4e-02 1.9e-01 5.6e-03 3.7e-01
2 LHb gene expression Htr7 0.15 0.09 1.1e-03 0.13 0.07 0.1 0.07 5.4e-04 7.7e-03 2.3e-03 8.4e-03
3 IL gene expression Htr7 0.19 0.1 1.8e-04 0.13 0.15 0.13 0.1 6.1e-04 2.0e-04 5.9e-04 2.4e-03
4 Adipose alternative polyA XM_006231307.3 0.07 0.04 2.0e-05 0.04 0.04 0.03 0.04 5.6e-05 2.7e-05 1.9e-04 8.1e-05
5 Adipose alternative polyA XM_006231307.3 0.06 0.04 9.8e-05 0.02 0.03 0.02 0.02 2.2e-03 1.9e-04 3.2e-03 1.3e-03
6 Adipose alternative polyA XM_039089840.1 0.07 0.04 7.9e-05 0.02 0.03 0.02 0.02 9.4e-04 2.7e-04 1.3e-03 1.0e-03
7 NAcc gene expression Htr7 0.04 0.03 3.1e-03 0 0.02 0.01 0.01 7.8e-02 1.6e-03 6.5e-03 8.2e-03
8 Adipose isoform ratio XM_006231307.3 0.05 0.03 8.4e-04 0.02 0.02 0.02 0.02 1.7e-03 1.2e-03 4.6e-03 3.4e-03
9 Adipose gene expression Htr7 0.15 0.08 7.8e-07 0.06 0.04 0.05 0.05 9.0e-07 1.9e-05 2.1e-06 2.4e-06
10 Adipose isoform ratio XM_039089840.1 0.06 0.04 7.6e-04 0.02 0.01 0.02 0.02 1.6e-03 8.7e-03 2.7e-03 6.0e-03
11 Adipose alternative polyA XM_039089840.1 0.08 0.05 1.4e-05 0.04 0.04 0.04 0.04 1.0e-05 1.7e-05 2.2e-05 2.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density2.54.213.83.73.63.4-0.30.3-0.42.6-0.1-0.20.20.2
Area under the delay curve2.83.05.11.6-0.2-0.3-2.3-2.22.2-1.5-1.81.8-1.8-1.8
BMI with tail0.20.50.90.20.50.70.60.6-0.60.80.7-0.90.90.9
BMI without tail0.20.41.61.30.50.7-0.7-0.70.7-0.0-0.40.2-0.2-0.3
Body weight1.77.012.32.41.3-0.0-3.5-3.33.2-1.0-3.42.8-2.8-2.9
Weight adjusted by age0.30.30.70.50.80.70.30.6-0.60.60.5-0.30.30.3
Bone surface1.32.38.83.02.62.6-0.40.1-0.11.8-0.10.0-0.0-0.0
Bone volume1.72.910.43.23.12.5-0.9-0.40.41.8-0.70.4-0.4-0.4
Breakpoint value in progressive ratio session1.82.03.31.50.90.2-1.8-1.61.6-0.5-1.61.6-1.6-1.6
Number of licking bursts3.84.58.2-2.2-1.6-2.9-1.4-1.41.5-2.6-1.72.5-2.5-2.5
Context. condit. distance diff. score1.31.64.41.52.11.50.20.3-0.41.90.1-1.31.31.3
Locomotion velocity, session 11.21.33.6-1.9-1.7-1.11.21.1-1.1-0.71.2-0.50.50.4
Locomotion distance, session 10.10.20.4-0.7-0.7-0.40.50.5-0.5-0.10.4-0.30.30.2
Locomotion velocity, session 20.40.51.5-1.2-0.8-0.80.70.6-0.5-0.30.6-0.60.60.5
Locomotion distance, session 20.71.02.3-1.1-1.0-1.5-0.7-0.70.8-1.1-0.91.0-1.0-1.0
Locomotion velocity, session 30.10.20.50.20.7-0.1-0.5-0.40.4-0.0-0.50.3-0.3-0.4
Locomotion distance, session 30.40.41.00.30.7-0.2-0.9-0.80.8-0.0-1.00.5-0.5-0.5
Stereotopy head waving bouts, day 31.01.22.00.30.51.11.11.1-1.10.91.4-1.21.21.3
Stereotopy head waving duration, day 30.81.01.70.80.51.30.90.9-0.90.91.2-1.01.01.1
Locomotion velocity, session 70.50.61.61.31.10.6-0.8-0.80.80.4-0.80.2-0.2-0.3
Locomotion distance, session 70.40.51.51.21.10.7-0.8-0.70.70.4-0.70.4-0.4-0.4
Stereotopy head waving bouts, day 70.00.00.1-0.0-0.20.00.10.1-0.1-0.10.3-0.00.00.1
Stereotopy head waving duration, day 70.10.10.20.1-0.20.20.30.3-0.30.00.5-0.20.20.2
Locomotion velocity, session 80.20.20.30.10.40.30.40.4-0.40.50.3-0.60.60.6
Locomotion distance, session 80.40.51.20.30.80.40.40.3-0.31.10.1-1.01.01.1
Degree of sensitization distance0.10.10.30.6-0.00.4-0.2-0.30.3-0.1-0.10.2-0.2-0.1
Degree of sensitization stereotypy0.00.00.00.1-0.00.0-0.1-0.10.1-0.10.00.1-0.1-0.2
Conditioned locomotion0.20.21.40.41.20.4-0.00.1-0.10.7-0.30.1-0.1-0.1
Cocaine response after cond. corrected0.30.31.11.10.80.7-0.5-0.40.40.1-0.10.5-0.5-0.5
Cocaine response after cond. not corrected1.31.42.61.60.70.5-1.5-1.41.4-0.4-1.11.2-1.2-1.2
Cocaine response before conditioning1.72.13.70.8-0.9-0.7-1.8-1.91.9-1.4-1.61.4-1.4-1.4
Saline control response0.50.73.41.80.51.2-0.9-1.00.90.1-0.30.2-0.2-0.2
Bone: connectivity density1.93.08.92.72.43.00.61.1-1.12.40.9-0.70.70.7
Bone: cortical apparent density0.40.51.3-0.5-0.80.00.80.6-0.6-0.21.2-0.80.80.8
Bone: cortical area2.13.25.52.22.00.7-2.3-2.02.00.1-2.21.5-1.5-1.5
Bone: cortical porosity0.10.10.5-0.7-0.5-0.40.40.3-0.2-0.20.3-0.10.10.1
Bone: cortical porosity0.00.00.1-0.3-0.2-0.20.10.0-0.0-0.1-0.00.1-0.1-0.1
Bone: cortical thickness2.84.67.71.00.6-0.8-2.8-2.62.6-1.5-2.62.5-2.5-2.5
Bone: cortical thickness1.01.21.6-0.00.1-0.9-1.2-1.21.3-1.0-1.21.3-1.3-1.3
Bone: cortical tissue density0.50.61.6-0.6-0.80.01.00.8-0.7-0.21.2-0.80.80.8
Condit. Reinf. active minus inactive responses1.01.11.7-0.5-0.8-1.2-1.0-1.01.1-1.3-0.91.1-1.1-1.1
Condit. Reinf. active-inactive response ratio0.50.51.7-1.2-1.3-0.90.50.4-0.4-0.70.5-0.10.10.1
Condit. Reinf. active responses1.11.32.50.90.3-0.3-1.6-1.61.6-0.7-1.41.2-1.2-1.1
Condit. Reinf. inactive responses1.61.94.32.11.60.8-1.8-1.61.50.2-1.51.0-1.0-1.0
Incentive salience index mean2.32.83.6-0.4-1.1-1.6-1.8-1.91.9-1.8-1.71.8-1.8-1.8
Condit. Reinf. lever presses1.52.02.8-0.4-1.3-1.3-1.5-1.71.7-1.6-1.31.4-1.4-1.4
Condit. Reinf. active minus inactive responses0.81.02.00.90.5-0.1-1.4-1.31.3-0.2-1.40.9-0.9-0.9
Condit. Reinf. active-inactive response ratio0.20.20.50.30.3-0.2-0.6-0.60.6-0.1-0.70.4-0.4-0.4
Condit. Reinf. active responses1.52.04.72.21.50.8-1.8-1.61.50.2-1.61.1-1.1-1.1
Condit. Reinf. inactive responses1.21.43.61.91.20.8-1.5-1.31.20.1-1.21.0-1.0-1.0
Condit. Reinf. lever presses0.20.20.40.50.50.2-0.6-0.50.50.0-0.60.5-0.5-0.5
Condit. Reinf. lever reinforcers received1.11.53.21.81.20.6-1.6-1.41.40.1-1.51.0-1.0-1.0
Conditioned reinforcement - actives0.80.83.11.81.00.9-1.0-0.80.80.3-0.90.6-0.6-0.5
Conditioned reinforcement - inactives1.01.14.22.11.31.90.20.3-0.31.40.4-0.50.50.5
Conditioned locomotion0.80.92.00.80.51.40.90.9-0.91.11.0-0.80.80.9
Patch foraging indifference point 0 sec2.03.24.6-0.0-0.9-1.3-2.0-1.92.0-1.9-1.82.1-2.1-2.1
Patch foraging indifference point AUC2.12.44.10.9-0.9-0.5-1.9-2.02.0-1.9-1.21.6-1.6-1.6
Delay disc. indifference point, 0s delay2.02.23.91.60.60.1-2.0-1.91.9-0.6-1.81.5-1.5-1.5
Delay disc. indifference point, 16s delay1.51.54.42.10.60.7-1.6-1.41.4-0.4-1.11.0-1.0-1.0
Delay disc. indifference point, 2s delay0.30.31.81.30.30.7-0.6-0.50.5-0.1-0.20.3-0.3-0.3
Delay disc. indifference point, 24s delay3.23.15.71.2-1.0-0.6-2.2-2.42.4-1.8-1.81.7-1.7-1.7
Delay disc. indifference point, 4s delay3.13.35.61.50.1-0.3-2.4-2.32.3-1.4-2.02.0-2.0-2.0
Delay disc. indifference point, 8s delay2.32.43.90.6-1.3-0.9-1.8-1.81.8-2.0-1.21.7-1.7-1.7
Indifference point function ln k0.71.02.9-0.31.30.51.01.1-1.11.70.4-1.01.01.0
Indifference point function log k0.71.02.9-0.31.30.51.01.1-1.11.70.4-1.01.01.0
Patch foraging total patch changes 0 sec1.93.04.40.0-0.9-1.2-1.9-1.91.9-1.9-1.82.1-2.1-2.1
Patch foraging total patch changes 12 sec1.52.04.4-0.1-1.4-1.0-1.3-1.41.5-2.1-0.81.6-1.6-1.6
Patch foraging total patch changes 18 sec1.62.03.00.4-0.4-0.7-1.7-1.71.7-1.6-1.31.7-1.7-1.7
Patch foraging total patch changes 24 sec3.94.86.80.5-0.7-1.4-2.6-2.62.6-2.3-2.32.5-2.5-2.5
Patch foraging total patch changes 6 sec2.84.27.50.2-1.6-1.4-2.2-2.32.3-2.7-1.62.3-2.3-2.3
Patch foraging time to switch 0 sec0.71.15.5-2.3-0.9-1.31.11.1-1.0-0.40.7-0.10.10.1
Patch foraging water rate 0 sec0.20.21.01.00.50.7-0.4-0.40.40.5-0.3-0.30.30.3
Patch foraging water rate 12 sec0.60.81.40.50.1-0.3-1.1-1.01.0-0.5-1.21.2-1.2-1.2
Patch foraging water rate 18 sec0.20.30.80.80.30.2-0.8-0.70.70.2-0.90.3-0.3-0.3
Patch foraging water rate 24 sec1.41.93.71.91.00.5-1.9-1.81.7-0.1-1.81.1-1.1-1.1
Patch foraging water rate 6 sec0.10.20.30.20.50.40.40.4-0.40.60.4-0.50.50.5
Seeking ratio, delayed vs. immediate footshock0.10.10.3-0.50.0-0.30.40.3-0.30.20.1-0.30.30.3
Distance traveled before self-admin0.00.00.10.2-0.1-0.0-0.1-0.30.3-0.0-0.1-0.10.10.1
Distance traveled after self-admin2.52.85.21.41.52.31.51.7-1.72.01.8-1.51.51.5
Extensor digitorum longus weight0.31.02.01.40.70.3-1.3-1.41.40.1-1.40.5-0.5-0.5
Bone: elastic displacement4.34.98.4-2.2-1.2-0.22.92.7-2.70.82.7-2.32.32.3
Bone: elastic work4.76.19.7-1.5-0.70.63.13.0-3.01.53.0-2.92.92.9
Bone: endosteal estimation1.53.39.03.03.03.00.00.4-0.52.60.1-0.80.80.8
Bone: endosteal perimeter1.63.28.22.22.92.60.61.1-1.12.80.4-1.21.21.2
Epididymis fat weight1.02.33.80.50.2-0.8-1.9-1.81.9-1.1-1.91.7-1.7-1.7
Delta time in closed arm before/after self-admin3.23.18.0-2.5-1.6-2.8-1.0-1.11.1-2.1-1.41.6-1.6-1.6
Delta time in open arm before/after self-admin2.12.04.92.01.32.20.70.8-0.91.71.1-1.41.41.4
Diff in mean of infusions in LGA sessions0.10.10.3-0.40.3-0.5-0.2-0.20.20.1-0.5-0.00.00.0
Delay discount exponential model param3.13.35.5-1.50.30.42.32.3-2.31.61.9-1.91.91.9
Extinction: sum of active levers before priming0.40.40.90.50.1-0.3-0.9-0.90.9-0.4-1.00.5-0.5-0.5
Active lever presses in extinction session 60.90.92.81.71.41.1-0.8-0.60.60.6-0.70.7-0.7-0.7
Bone: final force0.71.22.01.10.70.1-1.4-1.31.2-0.2-1.41.2-1.2-1.2
Bone: final moment0.50.71.21.00.70.3-1.1-0.90.9-0.1-1.10.9-0.9-0.9
Food consumed during 24 hour testing period1.41.72.6-0.8-0.7-1.4-1.2-1.11.1-1.5-1.31.6-1.6-1.6
Glucose0.00.10.4-0.5-0.1-0.60.00.0-0.0-0.2-0.2-0.10.10.1
Heart weight0.20.31.0-0.7-1.0-0.8-0.1-0.10.1-0.7-0.20.2-0.2-0.3
Delay discount hyperbolic model param2.42.54.3-1.50.30.32.12.0-2.01.41.6-1.71.71.7
Intermittent access intake day 1-15 change0.60.61.10.90.91.00.50.6-0.71.10.5-0.80.80.8
Intermittent access intake escalation0.30.30.50.50.60.60.30.4-0.40.70.3-0.60.60.5
Intermittent access intake escalation 20.60.60.9-0.30.40.30.91.0-1.00.80.8-1.01.01.0
Intermitt. access day 1 inactive lever presses1.21.32.41.10.81.60.91.0-1.01.41.1-1.11.11.1
Intermitt. access day 15 inactive lever presses2.12.36.92.41.72.60.71.0-1.01.81.2-0.90.91.0
Intermitt. access escalation Index0.10.10.30.5-0.40.2-0.3-0.40.4-0.2-0.1-0.10.1-0.0
Intermittent access day 1 total infusions0.40.51.91.40.90.8-0.7-0.60.60.5-0.60.2-0.2-0.1
Intermittent access day 15 total infusions0.60.73.51.91.01.1-0.8-0.70.60.6-0.70.0-0.0-0.0
Intermittent access terminal intake (last 3 days)0.40.51.71.30.71.10.10.0-0.10.90.1-0.60.60.6
Intermittent access total infusions0.30.41.31.10.80.9-0.1-0.10.10.8-0.2-0.40.40.4
Intermittent access day 1 locomotion0.30.30.80.90.50.3-0.8-0.80.70.2-0.80.2-0.2-0.2
Intermittent access day 15 total locomotion1.11.21.90.70.91.30.90.9-1.01.40.9-1.31.31.3
Intermittent access total locomotion0.20.20.40.30.40.50.30.3-0.30.70.2-0.60.60.6
Intermittent access standard deviation0.40.40.70.60.60.80.50.5-0.50.80.5-0.60.60.6
Left kidney weight2.15.89.40.4-0.4-1.7-3.0-3.03.0-2.0-3.12.7-2.7-2.6
Right kidney weight3.710.514.0-0.2-1.4-2.7-3.6-3.73.7-3.3-3.63.7-3.7-3.7
Cocaine induced anxiety0.00.00.10.30.00.1-0.3-0.20.2-0.0-0.20.1-0.1-0.1
Post-drug Anxiety0.50.61.30.90.31.20.50.7-0.70.70.9-0.80.80.8
Baseline Anxiety0.30.30.50.30.30.60.50.6-0.60.40.7-0.50.50.5
Tail length3.29.717.43.21.00.1-4.2-4.04.0-1.7-3.63.2-3.2-3.2
Length with tail5.419.732.73.41.1-0.7-5.7-5.45.3-2.5-5.45.1-5.1-5.1
Length without tail3.26.911.81.30.9-0.8-3.3-3.03.0-1.2-3.43.3-3.3-3.2
Times rat made contact with spout0.80.91.61.00.40.2-1.3-1.21.2-0.3-1.11.0-1.0-1.0
Lifetime Intake0.20.21.11.00.60.7-0.2-0.30.20.5-0.3-0.20.20.2
Liver weight, left2.03.16.71.21.5-0.3-2.3-2.02.0-0.3-2.61.8-1.8-1.8
Liver weight, right3.05.08.41.20.0-0.9-2.9-2.92.9-1.6-2.82.4-2.4-2.4
Locomotor activity0.40.61.8-1.3-0.8-1.1-0.0-0.00.1-0.8-0.20.9-0.9-0.9
Locomotor testing distance0.60.93.3-1.8-1.1-1.40.10.10.0-1.1-0.10.9-0.9-0.9
Locomotor testing rearing0.10.20.3-0.50.3-0.4-0.3-0.30.3-0.1-0.50.5-0.5-0.5
Locomotion in novel chamber3.13.96.6-0.31.81.42.12.3-2.32.61.7-2.12.12.1
Locomotion in novel chamber post-restriction0.81.03.81.41.90.8-0.9-0.70.71.0-1.10.1-0.1-0.1
Fecal boli incidents, locomotor time 10.30.30.50.6-0.30.70.50.3-0.30.50.5-0.70.70.7
Change in fecal boli incidents, locomotor task0.30.30.4-0.1-0.3-0.4-0.5-0.50.5-0.6-0.40.7-0.7-0.7
Time >=10cm from walls, locomotor time 11.51.53.61.91.70.8-1.5-1.41.30.6-1.60.5-0.5-0.5
Bouts of movement, locomotor time 10.91.02.1-0.60.1-0.8-0.8-0.70.8-0.7-1.11.5-1.5-1.5
Total resting periods, locomotor time 11.31.43.00.00.2-0.5-1.2-1.11.1-0.7-1.31.7-1.7-1.7
Rest time, locomotor task time 10.10.20.4-0.10.20.50.60.6-0.60.30.6-0.10.10.1
Distance moved, locomotor task time 11.21.32.60.6-0.3-0.7-1.6-1.61.6-1.0-1.41.0-1.0-1.0
Vertical activity count, locomotor time 10.10.10.3-0.3-0.0-0.6-0.4-0.40.4-0.3-0.50.1-0.1-0.1
Time >=10cm from walls, locomotor time 21.82.03.81.70.10.1-2.0-1.91.9-0.7-1.71.2-1.2-1.2
Bouts of movement, locomotor time 21.21.33.0-1.0-1.7-1.5-0.6-0.90.9-1.6-0.60.9-0.9-0.9
Total resting periods, locomotor time 21.71.83.6-1.3-1.8-1.8-0.8-1.11.1-1.9-0.81.2-1.2-1.2
Rest time, locomotor task time 21.61.83.0-1.4-0.6-1.6-0.9-1.01.0-1.3-1.31.7-1.7-1.7
Distance moved, locomotor task time 20.30.41.91.40.50.7-0.6-0.60.50.3-0.3-0.40.40.4
Vertical activity count, locomotor time 20.30.30.60.6-0.60.40.20.2-0.20.00.6-0.80.80.8
Light reinforcement 10.10.20.90.50.90.70.20.5-0.50.60.20.1-0.1-0.1
Light reinforcement 21.01.32.7-1.2-1.2-0.21.51.5-1.4-0.11.6-0.80.80.8
Bone: marrow area1.63.69.63.13.13.10.10.5-0.62.80.2-0.90.90.9
Bone: maximum diameter2.75.018.93.64.33.3-0.20.3-0.43.2-0.3-0.90.90.9
Bone: maximum force0.61.13.61.91.51.2-1.0-0.70.70.8-1.00.5-0.5-0.5
Bone: maximum moment0.50.82.91.71.41.2-0.7-0.40.40.8-0.60.4-0.4-0.4
Mean time between licks in bursts0.81.13.3-1.8-1.5-1.11.10.9-0.9-0.50.9-0.70.70.7
Mean num. licks in bursts2.93.48.12.61.72.90.80.8-0.92.41.1-1.91.91.9
Cd content in liver0.40.40.8-0.2-0.8-0.5-0.6-0.60.6-0.9-0.40.7-0.7-0.7
Co content in liver1.72.04.4-0.2-0.61.01.71.7-1.70.82.1-1.51.51.5
Cu content in liver0.50.61.8-1.1-1.3-0.70.40.4-0.4-1.10.70.5-0.5-0.5
Fe content in liver1.92.38.3-2.9-2.5-2.50.40.1-0.0-1.80.10.4-0.4-0.4
K content in liver0.10.10.3-0.6-0.3-0.30.30.2-0.2-0.10.2-0.20.20.2
Mg content in liver0.20.20.6-0.8-0.7-0.7-0.0-0.10.2-0.80.00.3-0.3-0.3
Mn content in liver0.91.02.3-1.3-1.4-1.5-0.4-0.60.6-1.5-0.40.8-0.8-0.8
Na content in liver0.50.61.6-1.1-0.8-1.3-0.4-0.50.6-1.0-0.40.5-0.5-0.5
Rb content in liver0.30.30.70.10.4-0.4-0.7-0.60.6-0.3-0.80.6-0.6-0.6
Se content in liver7.79.430.0-5.1-5.5-4.70.3-0.20.3-4.40.41.4-1.4-1.4
Sr content in liver2.32.13.10.50.71.51.61.7-1.71.51.8-1.51.51.5
Zn content in liver3.13.512.4-3.5-3.4-2.80.90.4-0.3-2.10.7-0.20.20.2
Bone: minimum diameter1.32.48.22.92.82.0-1.2-0.80.71.7-1.20.2-0.2-0.2
Time in familiar zone, hab. session 10.10.10.20.10.10.40.30.3-0.30.20.40.1-0.1-0.1
Time in novel zone, hab. session 10.30.31.1-1.1-0.6-1.10.0-0.00.1-0.7-0.10.1-0.1-0.1
Total zone transitions, hab. session 10.10.10.50.20.70.1-0.00.1-0.10.1-0.00.3-0.3-0.3
Total locomotion distance, hab. session 10.20.31.3-1.1-0.1-0.90.10.1-0.1-0.5-0.10.5-0.5-0.5
Locomotion velocity, hab. session 10.20.31.4-1.2-0.3-1.00.10.1-0.0-0.5-0.10.3-0.3-0.3
Time in familiar zone, hab. session 20.10.10.4-0.4-0.7-0.10.50.4-0.4-0.20.5-0.20.20.2
Time in novel zone, hab. session 20.10.10.20.10.40.20.20.3-0.30.30.2-0.30.30.3
Total zone transitions, hab. session 20.50.71.2-0.6-0.7-1.1-0.6-0.50.5-1.1-0.51.0-1.0-1.0
Total locomotion distance, hab. session 20.50.62.5-1.6-0.8-1.50.00.00.0-0.9-0.20.6-0.6-0.6
Locomotion velocity, hab. session 20.60.82.6-1.6-0.8-1.6-0.1-0.20.2-1.0-0.40.7-0.7-0.8
Novel to familiar place preference ratio0.30.31.31.10.80.9-0.3-0.10.10.5-0.30.4-0.4-0.3
Novelty place preference0.30.31.21.10.81.0-0.10.1-0.10.7-0.00.2-0.2-0.0
Time in novel zone, NPP test0.10.10.30.50.60.5-0.00.1-0.10.4-0.10.3-0.3-0.2
Total zone transitions, NPP test0.91.32.6-1.1-0.8-1.6-0.9-1.01.0-1.5-1.01.1-1.1-1.2
Total locomotion distance, NPP test0.40.61.9-1.3-0.8-1.4-0.2-0.30.4-1.0-0.30.3-0.3-0.5
Locomotion velocity, NPP test0.40.61.3-0.7-0.8-1.2-0.6-0.70.8-1.1-0.60.5-0.5-0.7
Intraocular pressure0.20.20.90.30.9-0.0-0.5-0.20.20.0-0.50.5-0.5-0.6
Delta distance traveled before/after self-admin2.02.14.21.51.82.11.01.2-1.21.91.1-1.31.31.3
Delta ambulatory time before/after self-admin2.72.97.32.42.22.70.71.0-1.02.21.0-1.31.31.3
Parametrial fat weight1.22.34.41.10.2-0.4-2.0-2.12.1-1.0-1.91.5-1.5-1.4
Pavlov. Cond. lever latency0.60.81.50.00.80.81.01.2-1.20.81.0-0.70.70.7
Pavlov. Cond. magazine entry latency1.41.84.4-1.6-1.8-2.1-0.8-1.01.1-1.7-1.01.0-1.0-1.0
Pavlov. Cond. change in total contacts1.61.73.1-1.0-1.6-1.7-1.0-1.21.2-1.7-1.01.2-1.2-1.2
Pavlov. Cond. index score2.12.73.7-0.7-1.3-1.8-1.7-1.91.9-1.7-1.91.6-1.6-1.6
Pavlov. Cond. latency score2.22.94.5-0.3-1.1-1.7-2.0-2.12.1-1.6-2.01.6-1.6-1.6
Pavlov. Cond. lever contacts1.72.03.0-0.3-1.2-1.4-1.6-1.71.7-1.5-1.61.4-1.4-1.4
Pavlov. Cond. magazine entry number0.91.13.01.41.51.70.60.7-0.81.30.8-0.80.80.7
Pavlov. Cond. intertrial magazine entries0.91.12.41.51.20.7-1.2-1.11.10.1-1.00.9-0.9-0.9
Pavlov. Cond. lever-magazine prob. diff.2.32.94.5-1.1-1.7-2.1-1.6-1.81.8-1.9-1.81.6-1.6-1.6
Pavlov. Cond. response bias1.51.84.5-1.8-1.9-2.1-0.7-0.90.9-1.7-0.91.0-1.0-1.0
Pavlov. Cond. lever latency0.10.10.4-0.6-0.1-0.30.40.3-0.30.30.1-0.20.20.2
Pavlov. Cond. magazine entry latency0.81.01.7-0.7-0.7-1.3-0.8-0.90.9-1.3-0.81.0-1.0-1.0
Pavlov. Cond. change in total contacts0.60.81.60.9-0.1-0.1-1.2-1.31.2-0.7-0.90.8-0.8-0.8
Pavlov. Cond. index score0.81.01.70.60.1-0.4-1.3-1.31.3-0.9-1.11.1-1.1-1.1
Pavlov. Cond. latency score0.60.81.50.70.3-0.2-1.2-1.11.1-0.6-1.00.9-0.9-0.9
Pavlov. Cond. lever contacts0.10.20.40.60.20.1-0.6-0.60.6-0.4-0.30.5-0.5-0.5
Pavlov. Cond. magazine entry number1.41.73.11.01.21.71.11.2-1.31.81.0-1.31.31.3
Pavlov. Cond. intertrial magazine entries0.91.22.01.01.00.1-1.3-1.21.2-0.1-1.41.2-1.2-1.2
Pavlov. Cond. lever-magazine prob. diff.1.01.32.10.4-0.1-0.6-1.5-1.41.4-1.1-1.31.2-1.2-1.2
Pavlov. Cond. response bias0.91.21.9-0.0-0.6-0.9-1.2-1.21.3-1.4-1.01.3-1.3-1.3
Time in closed arm before self-admin0.30.30.60.60.10.70.50.5-0.50.50.7-0.50.50.5
Time in closed arm after self-admin1.92.03.1-0.8-1.1-1.6-1.3-1.41.5-1.8-1.31.5-1.5-1.5
Time in open arm before self-admin0.30.31.7-1.3-0.6-1.0-0.0-0.00.1-0.6-0.20.3-0.3-0.3
Time in open arm after self-admin0.80.82.00.91.41.40.50.8-0.81.40.5-0.50.50.5
Bone: periosteal estimation1.53.110.63.23.32.5-1.0-0.50.42.1-0.90.1-0.1-0.1
Bone: periosteal perimeter1.22.06.72.52.61.9-0.9-0.50.51.7-1.00.2-0.2-0.2
Bone: post-yield work3.24.47.22.31.20.4-2.7-2.42.4-0.7-2.52.3-2.3-2.3
Progressive ratio test 1 active lever presses1.01.03.61.91.41.70.00.1-0.11.20.2-0.60.60.7
Progressive ratio test 1 breakpoint0.80.93.01.71.21.60.10.1-0.21.20.3-0.60.60.7
Progressive ratio test 1 inactive lever presses0.91.04.92.21.31.7-0.5-0.40.40.9-0.10.1-0.1-0.1
Progressive ratio test 2 active lever presses1.01.03.01.51.71.50.10.2-0.31.50.0-0.70.70.8
Progressive ratio test 2 breakpoint1.51.64.31.82.11.80.20.4-0.51.80.2-1.01.01.1
Progressive ratio test 2 inactive lever presses2.12.44.81.71.62.21.11.2-1.22.01.1-1.51.51.5
Incentive Sensitization - Responses0.50.51.81.01.41.0-0.10.1-0.21.0-0.2-0.30.30.3
Incentive Sensitization - Breakpoint0.60.61.91.11.41.1-0.00.2-0.21.1-0.1-0.40.40.4
Sum of active levers in priming session hrs 5-60.30.30.90.20.20.70.60.7-0.70.11.0-0.10.10.1
Progressive ratio0.30.41.1-0.3-0.0-0.7-0.7-0.70.7-0.3-1.00.5-0.5-0.5
Food seeking constrained by brief footshock0.30.31.4-0.10.6-0.6-0.6-0.60.60.2-1.20.4-0.4-0.4
Seeking ratio, punishment vs. effort0.10.10.20.1-0.0-0.3-0.4-0.40.4-0.4-0.40.5-0.5-0.5
Retroperitoneal fat weight0.20.51.10.30.6-0.2-1.0-0.80.8-0.2-1.10.7-0.7-0.7
Reaction time number correct0.81.13.31.71.81.70.10.2-0.31.40.1-0.50.50.5
Reaction time mean minus median0.60.81.4-0.7-0.00.11.21.2-1.20.61.1-1.01.01.0
Reaction time mean minus median AUC0.60.71.3-0.5-0.10.21.11.1-1.10.51.1-0.90.90.9
Reaction time num false alarms1.01.32.80.71.0-0.4-1.5-1.41.4-0.4-1.71.1-1.1-1.1
Reaction time num false alarms AUC1.21.73.30.10.6-0.9-1.6-1.51.5-0.9-1.81.4-1.4-1.4
Reaction time trials correct on left0.81.13.31.71.81.70.10.2-0.31.40.1-0.50.50.5
Reaction time trials on left0.71.03.31.71.81.60.00.2-0.21.40.0-0.40.40.4
Reaction time mean1.21.75.7-2.4-1.8-1.41.41.2-1.1-0.71.2-0.70.70.7
Reaction time mean AUC1.72.36.9-2.6-2.1-1.41.71.4-1.3-0.71.5-1.01.01.0
Median of all reaction times1.62.37.0-2.6-2.1-1.51.61.3-1.3-0.71.4-0.90.90.9
Reaction time omissions0.00.00.1-0.30.1-0.3-0.00.00.0-0.1-0.0-0.20.20.2
Reaction time false alarm rate1.21.62.6-0.5-0.0-1.3-1.4-1.31.4-1.2-1.61.4-1.4-1.4
Reaction time premature initiation rate0.70.91.50.90.9-0.1-1.2-1.11.1-0.3-1.20.9-0.9-0.9
Reaction time premature initiations1.11.54.32.02.10.9-1.3-1.01.00.5-1.30.8-0.8-0.8
Std. dev. reaction times0.40.61.6-1.3-0.7-0.60.90.8-0.8-0.20.9-0.60.60.6
Reaction time trials completed0.71.03.31.71.81.60.00.2-0.21.40.0-0.40.40.4
Reaction time trials AUC0.50.82.41.51.51.4-0.00.1-0.11.20.0-0.30.30.3
Run reversals in cocaine runway, females0.80.81.5-0.70.20.31.21.2-1.20.71.1-0.80.80.8
Run reversals in cocaine runway, males1.21.21.9-0.9-0.8-1.4-0.9-0.90.9-1.3-1.11.2-1.2-1.2
Latency to leave start box in cocaine runway1.71.93.81.31.91.50.60.7-0.81.90.6-1.61.61.6
Latency to leave start box in cocaine runway, F1.11.22.20.71.21.00.70.7-0.71.40.8-1.51.51.5
Latency to leave start box in cocaine runway, M0.40.41.80.91.40.6-0.3-0.10.10.8-0.4-0.20.20.2
Std. dev. time between licks in bursts1.21.55.8-2.4-2.1-1.70.80.6-0.6-1.20.6-0.20.20.2
Total sessions with >9 infusions0.10.20.40.4-0.1-0.1-0.6-0.60.6-0.3-0.50.2-0.2-0.2
Short access day 1 total inactive lever presses2.83.15.61.41.32.41.71.8-1.82.12.0-1.61.61.4
Short access day 10 total inactive lever presses0.30.31.51.2-0.40.9-0.0-0.10.1-0.10.50.3-0.3-0.2
Short access day 1 total infusions0.30.30.60.6-0.40.0-0.6-0.70.8-0.5-0.40.4-0.4-0.6
Short access day 10 total infusions0.20.20.8-0.0-0.9-0.3-0.3-0.50.5-0.7-0.20.2-0.2-0.3
Short access total infusions0.30.31.01.00.30.3-0.7-0.80.7-0.1-0.60.4-0.4-0.5
Short access day 1 locomotion0.20.30.70.1-0.8-0.5-0.5-0.80.7-0.6-0.4-0.00.00.1
Short access day 10 total locomotion0.20.20.3-0.6-0.3-0.10.50.4-0.40.20.3-0.50.50.5
Short access total locomotion0.10.20.5-0.4-0.7-0.5-0.2-0.30.3-0.5-0.20.2-0.2-0.2
One hour access (0.3 mA shock)1.41.65.82.42.11.9-0.5-0.20.11.6-0.5-0.50.50.6
Compulsive drug intake1.11.14.92.21.21.2-1.1-1.11.00.5-0.90.2-0.2-0.2
One hour access (shock baseline)0.10.10.2-0.10.30.20.30.4-0.40.50.0-0.30.30.3
Social response proportion3.23.45.4-0.40.51.22.22.3-2.31.92.1-2.02.02.0
Social responses1.01.31.90.50.51.41.21.3-1.31.31.2-1.11.11.1
Social time0.50.72.5-0.6-1.6-0.9-0.4-0.60.6-1.2-0.30.7-0.7-0.7
Soleus weight0.92.54.31.21.62.11.31.4-1.52.11.3-1.61.61.6
Bone: stiffness1.52.44.42.01.20.5-2.0-1.91.80.0-2.11.4-1.4-1.4
Tibialis anterior weight0.41.24.62.11.11.1-1.2-1.31.20.7-1.10.1-0.1-0.1
Time to tail flick, vehicle, before self-admin0.70.71.3-0.5-0.40.21.01.0-1.00.21.1-0.90.90.9
Time to tail flick, vehicle, after self-admin2.12.24.00.60.4-0.6-1.9-1.91.8-0.8-2.01.7-1.7-1.7
Time to tail flick, test, before self-admin1.11.03.51.61.91.4-0.1-0.0-0.01.4-0.2-0.70.70.7
Time to tail flick, test, after self-admin0.20.20.91.0-0.30.4-0.5-0.60.6-0.3-0.10.1-0.1-0.1
Delta time to tail flick, vehicle, before/after SA3.73.77.01.51.4-0.1-2.5-2.32.3-0.4-2.62.0-2.0-2.0
Delta time to tail flick, test, before/after SA0.50.40.80.1-0.9-0.5-0.7-0.80.8-0.8-0.50.6-0.6-0.6
Tibia length0.51.52.50.50.6-0.4-1.5-1.31.4-0.8-1.41.6-1.6-1.6
Ambulatory time before self-admin0.20.20.7-0.7-0.8-0.50.20.0-0.0-0.30.2-0.30.30.3
Ambulatory time after self-admin3.33.65.71.41.82.41.61.7-1.82.31.8-1.91.91.9
Bone: tissue strength0.30.31.0-0.6-1.0-0.10.70.6-0.6-0.20.8-0.30.30.3
Total heroin consumption1.01.22.51.60.70.7-1.3-1.11.1-0.1-1.01.3-1.3-1.3
Bone: trabecular number1.62.59.23.02.62.7-0.20.3-0.42.00.10.0-0.0-0.0
Bone: trabecular spacing1.52.03.9-1.0-1.6-1.8-1.2-1.51.5-2.0-1.11.2-1.2-1.2
Bone: trabecular thickness1.01.24.61.92.11.6-0.40.0-0.01.3-0.40.4-0.4-0.4
Bone: trabecular tissue density1.42.05.31.82.32.10.30.5-0.51.90.4-1.21.21.2
Water consumed over 24 hours1.21.52.1-0.2-0.5-0.8-1.3-1.41.4-1.1-1.41.5-1.5-1.5
Number of responses in last shaping day0.80.83.11.81.21.50.10.1-0.21.10.3-0.60.60.6