Hub : Genes

Hrh1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc mRNA stability Hrh1 0.02 0.01 5.3e-05 0.02 0.02 0.03 0.02 1.8e-04 5.1e-04 9.0e-05 1.8e-04
2 Brain mRNA stability Hrh1 0.07 0.04 7.2e-09 0.08 0.1 0.09 0.09 3.8e-08 3.0e-09 2.1e-08 8.1e-09
3 BLA mRNA stability Hrh1 0.06 0.04 7.0e-03 0.04 0.03 0.01 0.02 4.5e-03 8.0e-03 7.0e-02 1.8e-02
4 PL mRNA stability Hrh1 0.03 0.02 3.0e-04 0.04 0.03 0.03 0.03 5.5e-05 2.3e-04 3.0e-04 2.5e-04
5 PL intron excision ratio chr4_149121009_149201504 0.03 0.02 1.8e-03 0.01 0.01 0.01 0 3.7e-02 3.1e-02 6.8e-02 1.3e-01
6 PL alternative TSS XM_039107019.2 0.06 0.04 2.5e-04 0.01 0.02 0.02 0.01 1.9e-02 1.5e-03 2.3e-03 1.5e-02
7 PL intron excision ratio chr4_149120573_149201504 0.05 0.03 9.8e-05 0.02 0.03 0.02 0.02 3.7e-03 1.2e-04 1.0e-03 4.3e-03
8 PL isoform ratio NM_017018.2 0.05 0.03 3.5e-04 0.01 0.02 0.02 0.01 5.1e-02 4.3e-03 2.2e-03 3.2e-02
9 PL isoform ratio XM_039107019.2 0.05 0.03 1.7e-04 0.01 0.02 0.02 0.01 3.1e-02 2.5e-03 2.0e-03 2.5e-02
10 NAcc gene expression Hrh1 0.17 0.06 0.0e+00 0.2 0.2 0.21 0.21 2.3e-30 1.1e-29 9.1e-31 5.3e-31
11 pVTA gene expression Hrh1 0.06 0.03 4.8e-05 0.05 0.07 0.06 0.06 4.9e-05 4.2e-06 1.3e-05 1.6e-05
12 PL alternative TSS NM_017018.2 0.06 0.04 4.9e-04 0.01 0.02 0.02 0.01 7.1e-02 5.2e-03 5.2e-03 6.1e-02
13 Adipose gene expression Hrh1 0.07 0.04 8.2e-04 0.03 0.03 0.03 0.03 2.2e-04 1.9e-04 3.5e-04 4.1e-04
14 BLA gene expression Hrh1 0.28 0.09 1.5e-13 0.23 0.26 0.26 0.25 1.5e-12 8.1e-14 5.3e-14 1.9e-13
15 OFC gene expression Hrh1 0.35 0.12 3.6e-07 0.14 0.27 0.26 0.25 4.2e-04 3.4e-07 8.6e-07 1.2e-06
16 LHb gene expression Hrh1 0.23 0.11 1.1e-03 0.05 0.04 0.05 0.01 2.8e-02 3.2e-02 2.1e-02 1.7e-01
17 IC gene expression Hrh1 0.31 0.11 7.7e-07 0.02 0.16 0.16 0.12 5.9e-02 3.2e-07 2.7e-07 6.8e-06
18 Brain gene expression Hrh1 0.45 0.1 0.0e+00 0.28 0.4 0.4 0.4 3.3e-26 6.5e-40 4.0e-39 2.4e-39
19 IL gene expression Hrh1 0.41 0.13 5.1e-06 0.09 0.18 0.16 0.17 3.0e-03 3.4e-05 1.4e-04 5.8e-05
20 PL gene expression Hrh1 0.4 0.09 0.0e+00 0.26 0.42 0.42 0.41 1.7e-28 2.5e-49 6.7e-49 5.2e-48

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density0.71.35.5-1.50.7-0.50.80.10.9-0.81.1-1.0-0.0-0.81.50.01.1-1.22.31.5-1.3-1.2-1.4
Area under the delay curve0.20.31.00.3-0.5-0.00.00.70.6-0.80.9-1.0-0.6-0.60.7-0.50.4-0.50.50.4-0.1-0.0-0.3
BMI with tail1.14.09.8-3.13.0-2.7-2.9-2.5-2.32.2-2.22.11.92.1-2.20.4-1.7-1.11.20.90.20.50.3
BMI without tail0.10.71.7-0.91.0-0.7-1.0-1.2-1.00.9-1.21.00.90.7-1.3-0.6-0.8-0.40.40.20.40.60.5
Body weight0.93.88.6-2.92.9-2.4-2.5-2.8-2.42.3-2.32.12.02.1-2.0-0.3-1.5-0.71.00.60.81.00.7
Weight adjusted by age0.10.30.80.9-0.60.70.40.80.6-0.80.8-0.7-0.7-0.60.7-0.10.3-0.5-0.00.3-0.5-0.4-0.4
Bone surface0.40.82.2-0.4-0.00.21.20.60.9-0.91.1-1.1-0.5-0.91.5-0.11.1-0.71.30.9-1.0-0.9-1.0
Bone volume0.30.62.7-1.20.7-0.60.7-0.10.4-0.30.7-0.70.1-0.41.10.10.7-0.81.61.0-0.9-0.9-1.0
Breakpoint value in progressive ratio session0.81.45.7-1.82.1-1.3-1.4-1.7-0.80.90.0-0.11.20.90.0-1.0-0.3-1.22.40.90.10.4-0.1
Number of licking bursts0.10.31.00.1-0.10.60.5-0.20.7-0.30.9-0.90.0-0.41.0-1.00.40.20.40.10.40.30.2
Context. condit. distance diff. score3.34.07.7-2.52.4-2.5-2.1-2.5-2.82.6-2.82.72.02.3-2.20.9-2.0-0.1-0.7-0.00.40.50.7
Locomotion velocity, session 10.40.41.70.8-0.40.5-0.0-0.1-0.50.3-0.70.80.50.4-1.3-0.8-0.70.50.0-0.70.50.70.8
Locomotion distance, session 10.40.51.70.9-0.60.60.6-0.2-0.20.1-0.50.50.60.1-0.8-1.3-0.50.7-0.6-0.70.81.01.0
Locomotion velocity, session 20.50.62.21.5-1.40.91.10.90.8-0.80.9-0.9-0.2-0.60.2-1.00.10.6-0.2-0.70.30.40.4
Locomotion distance, session 20.70.94.81.3-1.11.31.00.10.5-0.30.7-0.70.5-0.20.4-2.2-0.21.0-0.5-0.81.21.31.2
Locomotion velocity, session 30.80.92.40.3-1.00.50.91.61.2-1.40.6-0.6-1.3-1.30.30.61.1-0.70.40.7-1.1-1.0-1.0
Locomotion distance, session 30.80.91.6-0.1-0.90.61.11.21.1-1.30.9-0.9-1.0-1.21.1-0.11.1-0.80.71.0-1.0-0.8-0.8
Stereotopy head waving bouts, day 31.01.24.32.1-1.41.20.60.50.3-0.30.6-0.70.10.00.3-1.4-0.51.5-1.3-1.61.51.41.3
Stereotopy head waving duration, day 31.41.75.32.1-1.40.80.30.2-0.50.3-0.40.30.40.6-0.9-1.2-1.31.8-2.3-2.01.71.71.8
Locomotion velocity, session 70.50.51.4-0.0-0.40.31.00.80.7-0.80.2-0.1-0.8-0.90.20.61.0-0.70.80.6-1.2-1.1-1.0
Locomotion distance, session 70.81.03.2-1.50.8-0.60.10.2-0.0-0.2-0.50.6-0.5-0.4-0.41.10.8-1.71.31.5-1.8-1.5-1.4
Stereotopy head waving bouts, day 71.01.23.01.5-1.61.11.41.21.2-1.01.5-1.5-0.6-0.81.7-0.60.51.0-0.6-0.70.20.10.3
Stereotopy head waving duration, day 71.01.32.81.7-1.60.91.30.80.7-0.61.4-1.4-0.0-0.21.5-1.1-0.21.6-1.3-1.30.80.80.9
Locomotion velocity, session 80.70.82.1-0.10.5-0.2-0.2-1.3-0.71.0-0.60.61.40.9-0.6-1.1-1.01.00.0-0.81.21.21.2
Locomotion distance, session 82.43.46.5-1.71.7-1.8-1.3-2.5-2.52.4-2.52.32.52.1-2.1-0.7-2.20.7-0.9-0.61.31.51.6
Degree of sensitization distance0.91.03.5-0.91.1-1.0-0.6-0.9-1.21.1-1.81.90.70.8-1.81.0-0.6-0.30.0-0.0-0.5-0.4-0.2
Degree of sensitization stereotypy0.40.52.80.6-0.70.30.70.60.8-0.61.3-1.2-0.3-0.41.7-0.10.40.5-0.2-0.2-0.0-0.1-0.0
Conditioned locomotion1.11.35.8-1.11.2-0.2-0.6-0.20.9-0.60.2-0.1-0.5-0.90.21.01.5-1.72.41.7-1.2-1.4-1.7
Cocaine response after cond. corrected1.11.74.81.7-1.91.91.90.50.4-0.40.4-0.50.0-0.50.9-1.8-0.31.6-2.2-1.21.21.31.5
Cocaine response after cond. not corrected1.92.87.92.4-2.82.82.61.61.3-1.31.2-1.3-1.0-1.31.6-1.60.41.4-2.2-1.10.80.81.0
Cocaine response before conditioning0.91.12.91.0-1.41.30.81.71.2-1.41.2-1.2-1.6-1.20.90.31.1-0.3-0.10.2-0.7-0.7-0.7
Saline control response3.85.39.70.9-1.81.82.13.12.8-3.01.9-1.8-3.0-3.11.71.12.8-2.01.12.1-2.7-2.5-2.4
Bone: connectivity density0.20.31.6-0.60.4-0.40.7-0.10.2-0.30.3-0.30.3-0.30.7-0.50.3-0.61.30.5-0.5-0.3-0.5
Bone: cortical apparent density0.00.00.20.1-0.20.40.20.10.1-0.00.1-0.1-0.20.00.10.20.00.30.1-0.20.0-0.10.0
Bone: cortical area0.10.10.50.3-0.20.1-0.0-0.2-0.50.3-0.20.10.40.2-0.1-0.6-0.50.3-0.7-0.40.40.60.6
Bone: cortical porosity0.30.31.70.4-0.3-0.40.30.0-0.10.30.4-0.40.40.50.50.5-0.41.3-0.9-1.10.40.10.4
Bone: cortical porosity0.30.41.2-0.10.2-0.9-0.2-0.4-0.50.70.1-0.10.80.90.10.5-0.71.1-0.7-0.90.50.30.4
Bone: cortical thickness0.30.51.70.7-0.50.10.1-0.2-0.60.5-0.20.10.60.5-0.1-0.5-0.91.0-1.3-1.10.80.81.0
Bone: cortical thickness0.30.30.90.5-0.60.70.40.90.5-0.6-0.10.2-0.9-0.7-0.70.70.6-0.40.50.2-0.6-0.7-0.6
Bone: cortical tissue density0.00.00.10.0-0.10.40.10.10.10.00.1-0.1-0.20.10.10.20.00.30.1-0.20.1-0.1-0.0
Condit. Reinf. active minus inactive responses2.22.55.71.1-1.92.22.12.31.8-1.81.0-0.9-2.4-2.01.40.91.9-0.4-0.50.7-1.4-1.5-1.2
Condit. Reinf. active-inactive response ratio2.62.87.21.8-2.32.72.42.32.0-1.91.1-0.9-2.4-2.01.40.61.90.1-0.90.2-1.1-1.2-0.9
Condit. Reinf. active responses1.01.32.90.4-1.01.11.01.51.2-1.20.7-0.6-1.7-1.30.91.11.3-0.7-0.00.9-1.4-1.5-1.2
Condit. Reinf. inactive responses0.40.51.6-1.11.0-1.3-0.9-0.5-0.40.3-0.20.10.50.2-0.30.1-0.2-1.01.01.0-0.5-0.3-0.4
Incentive salience index mean1.51.94.21.5-1.92.02.11.91.6-1.51.2-1.1-1.9-1.51.60.51.40.4-0.90.0-0.8-0.9-0.5
Condit. Reinf. lever presses0.60.92.61.5-1.21.01.10.50.7-0.31.2-1.2-0.3-0.21.6-0.40.11.4-1.4-1.10.60.40.7
Condit. Reinf. active minus inactive responses0.40.62.81.5-1.40.91.71.20.3-0.7-0.00.0-0.7-0.70.20.10.20.4-1.0-0.7-0.5-0.30.0
Condit. Reinf. active-inactive response ratio0.40.62.30.9-0.60.20.60.0-0.80.5-1.00.90.20.5-0.7-0.2-0.90.8-1.5-1.20.40.50.8
Condit. Reinf. active responses0.50.72.11.2-1.21.11.41.30.7-0.90.2-0.1-1.1-1.00.30.50.7-0.1-0.4-0.1-0.8-0.7-0.5
Condit. Reinf. inactive responses1.42.14.20.1-0.41.00.91.41.8-1.71.0-0.9-1.8-1.81.01.02.0-1.51.61.7-1.7-1.8-1.9
Condit. Reinf. lever presses0.10.20.40.5-0.50.60.60.40.4-0.50.1-0.2-0.4-0.60.4-0.10.3-0.3-0.40.2-0.2-0.1-0.1
Condit. Reinf. lever reinforcers received0.60.93.11.4-1.51.31.81.50.8-1.10.1-0.1-1.0-1.20.30.20.7-0.0-0.6-0.1-0.8-0.6-0.4
Conditioned reinforcement - actives0.41.65.0-1.71.5-1.6-1.3-0.4-1.00.7-1.41.30.20.6-0.82.2-0.4-1.60.11.3-1.7-1.4-1.1
Conditioned reinforcement - inactives0.10.30.9-0.90.5-0.80.0-0.3-0.70.5-0.60.70.50.4-0.10.2-0.5-0.60.00.7-0.9-0.5-0.2
Conditioned locomotion0.40.62.7-0.50.3-0.70.1-0.1-0.90.4-1.61.60.20.3-1.30.4-0.5-0.8-0.10.6-1.1-0.6-0.2
Patch foraging indifference point 0 sec0.10.31.0-0.40.6-0.20.0-0.1-0.20.1-0.50.7-0.2-0.2-0.01.00.2-0.80.10.8-0.9-0.9-0.8
Patch foraging indifference point AUC0.51.13.71.5-1.71.91.11.51.2-1.20.0-0.0-1.9-1.3-0.20.10.90.2-0.90.10.0-0.1-0.1
Delay disc. indifference point, 0s delay0.60.61.8-0.50.2-0.5-0.50.80.5-0.70.4-0.4-0.9-0.60.00.90.7-1.40.91.2-1.2-1.1-1.1
Delay disc. indifference point, 16s delay0.00.00.20.4-0.3-0.40.00.3-0.1-0.10.3-0.3-0.00.00.4-0.1-0.10.00.0-0.3-0.10.00.1
Delay disc. indifference point, 2s delay0.40.41.5-1.10.6-1.2-0.90.0-0.2-0.10.2-0.30.20.0-0.00.1-0.3-1.20.81.2-0.7-0.4-0.6
Delay disc. indifference point, 24s delay0.50.81.61.2-1.21.01.00.81.0-1.01.2-1.3-0.6-0.71.2-1.20.70.40.0-0.40.50.50.3
Delay disc. indifference point, 4s delay0.20.20.70.1-0.2-0.2-0.10.50.6-0.70.8-0.9-0.5-0.50.4-0.10.4-0.50.40.4-0.2-0.2-0.4
Delay disc. indifference point, 8s delay0.30.51.70.7-0.90.70.50.90.8-1.01.1-1.1-0.6-0.70.6-1.30.5-0.30.50.30.20.40.1
Indifference point function ln k0.61.95.2-1.51.9-1.9-1.5-2.2-1.81.9-0.60.72.31.9-0.3-0.6-1.60.30.2-0.30.70.80.8
Indifference point function log k0.61.95.2-1.51.9-1.9-1.5-2.2-1.81.9-0.60.72.31.9-0.3-0.6-1.60.30.2-0.30.70.80.8
Patch foraging total patch changes 0 sec0.10.30.8-0.60.7-0.3-0.3-0.3-0.50.4-0.70.80.00.2-0.20.9-0.1-0.6-0.10.6-0.7-0.7-0.5
Patch foraging total patch changes 12 sec0.40.51.11.0-0.81.01.00.80.4-0.5-0.60.8-1.0-0.8-0.70.90.6-0.0-0.60.1-0.6-0.7-0.5
Patch foraging total patch changes 18 sec0.51.34.00.8-1.31.81.11.61.3-1.40.2-0.1-2.0-1.50.50.71.3-0.4-0.40.7-0.8-0.9-0.8
Patch foraging total patch changes 24 sec0.30.92.9-0.0-0.50.50.11.30.6-0.9-0.20.2-1.7-1.0-0.21.71.0-1.0-0.41.1-1.2-1.3-1.2
Patch foraging total patch changes 6 sec0.40.61.8-0.90.9-0.8-0.5-0.5-0.70.5-1.21.3-0.00.2-0.91.2-0.1-0.8-0.00.7-0.8-0.7-0.6
Patch foraging time to switch 0 sec0.10.52.8-1.31.1-1.2-0.8-0.5-0.10.10.5-0.60.80.20.50.10.2-0.61.70.4-0.3-0.3-0.6
Patch foraging water rate 0 sec0.20.62.90.9-0.40.10.4-0.1-0.60.7-0.40.60.10.8-0.10.7-0.81.4-1.7-1.30.40.20.7
Patch foraging water rate 12 sec0.00.20.4-0.30.20.0-0.1-0.6-0.50.6-0.60.60.30.5-0.3-0.3-0.50.1-0.70.10.10.30.4
Patch foraging water rate 18 sec0.10.30.8-0.50.6-0.7-0.8-0.5-0.70.8-0.10.20.20.8-0.00.9-0.50.3-0.4-0.30.1-0.10.1
Patch foraging water rate 24 sec0.20.31.80.1-0.20.10.3-0.3-0.60.6-0.60.70.20.5-0.00.1-0.50.6-1.3-0.40.10.20.6
Patch foraging water rate 6 sec0.10.20.60.6-0.20.30.5-0.3-0.20.4-0.20.20.20.40.3-0.3-0.40.8-0.7-0.70.40.40.6
Seeking ratio, delayed vs. immediate footshock0.81.23.8-0.91.1-0.9-1.7-1.2-1.51.2-1.71.60.91.2-1.90.1-1.0-0.4-0.10.10.50.70.6
Distance traveled before self-admin0.20.51.81.3-1.30.81.20.70.2-0.50.00.10.2-0.5-0.5-1.1-0.10.4-0.1-0.60.20.40.5
Distance traveled after self-admin0.30.51.50.4-0.70.60.31.20.6-0.7-0.10.1-1.2-0.7-0.31.20.8-0.5-0.10.5-1.0-1.0-0.8
Extensor digitorum longus weight3.313.232.2-4.65.2-5.4-5.7-4.7-4.54.3-4.03.83.94.2-3.81.0-3.3-1.20.50.51.11.41.0
Bone: elastic displacement1.31.63.4-0.70.00.60.21.01.4-1.40.8-0.8-1.4-1.50.90.81.8-1.71.61.8-1.4-1.5-1.7
Bone: elastic work0.20.31.5-0.90.6-0.2-0.5-0.10.1-0.3-0.20.10.0-0.4-0.2-0.30.5-1.21.11.2-0.3-0.1-0.5
Bone: endosteal estimation0.10.30.8-0.90.8-0.8-0.5-0.3-0.00.00.1-0.10.20.00.20.10.2-0.80.90.8-0.4-0.3-0.5
Bone: endosteal perimeter0.20.62.0-0.2-0.10.30.30.50.8-0.90.4-0.4-0.7-1.10.2-0.31.1-1.41.01.4-0.8-0.6-0.8
Epididymis fat weight0.10.72.7-1.10.8-0.2-0.6-0.00.4-0.50.4-0.5-0.4-0.50.6-0.10.7-1.61.51.4-0.8-0.6-0.9
Delta time in closed arm before/after self-admin1.31.23.60.10.3-1.1-0.1-1.1-1.41.3-0.80.81.91.3-1.0-0.6-1.71.2-0.9-1.50.81.01.2
Delta time in open arm before/after self-admin0.30.41.10.4-0.30.6-0.2-0.10.5-0.21.1-1.0-0.2-0.10.9-1.00.30.60.3-0.21.10.80.5
Diff in mean of infusions in LGA sessions0.40.72.6-1.10.8-0.2-0.2-0.20.5-0.40.3-0.4-0.1-0.60.20.10.7-1.41.61.6-0.9-0.9-1.0
Delay discount exponential model param0.30.41.2-0.40.6-0.1-0.1-0.8-0.70.9-1.11.10.60.6-0.80.7-0.50.5-0.5-0.40.1-0.00.2
Extinction: sum of active levers before priming0.30.41.5-0.50.6-1.00.0-0.10.1-0.20.6-0.60.7-0.10.70.10.2-0.81.20.8-0.8-0.6-0.7
Active lever presses in extinction session 62.02.04.0-1.41.7-2.0-1.5-1.8-2.01.8-1.51.31.91.9-1.5-0.2-1.8-0.00.2-0.30.50.80.7
Bone: final force0.50.81.9-0.60.7-1.2-1.0-0.9-1.41.2-0.90.81.01.3-0.80.4-1.20.5-0.8-0.60.50.50.6
Bone: final moment0.40.71.6-0.90.9-1.2-1.0-0.9-1.31.1-0.80.70.91.1-0.60.6-1.00.2-0.6-0.30.20.20.4
Food consumed during 24 hour testing period0.20.31.40.3-0.60.80.20.70.5-0.7-0.0-0.1-1.2-0.8-0.1-0.10.6-0.80.10.7-0.3-0.2-0.3
Glucose1.11.74.8-2.22.2-1.3-1.5-1.6-1.21.2-1.91.80.80.8-1.31.0-0.4-1.20.91.3-0.5-0.4-0.5
Heart weight0.20.30.8-0.20.20.4-0.9-0.4-0.50.3-0.80.8-0.20.2-0.9-0.3-0.3-0.3-0.50.20.60.60.4
Delay discount hyperbolic model param0.20.30.9-0.10.30.10.1-0.6-0.50.7-0.91.00.50.5-0.60.5-0.40.6-0.6-0.50.10.00.3
Intermittent access intake day 1-15 change0.31.85.20.41.1-1.4-1.4-1.2-1.91.7-2.12.31.11.6-2.20.7-1.60.1-0.9-0.60.20.40.7
Intermittent access intake escalation0.42.05.70.11.4-1.7-1.5-1.4-2.01.7-2.22.41.41.6-2.31.0-1.5-0.1-0.4-0.50.00.20.4
Intermittent access intake escalation 21.93.27.2-0.51.6-1.6-1.9-2.1-2.62.4-2.62.71.92.3-2.6-0.2-2.00.5-0.5-0.91.11.31.4
Intermitt. access day 1 inactive lever presses0.11.13.31.7-1.81.61.71.20.8-0.80.7-0.5-1.0-0.61.0-0.70.20.8-1.5-0.5-0.20.00.4
Intermitt. access day 15 inactive lever presses0.10.52.31.4-1.20.81.10.60.3-0.3-0.10.1-0.4-0.5-0.1-0.10.10.7-1.5-0.40.00.00.4
Intermitt. access escalation Index0.31.03.20.3-0.70.90.60.81.6-1.31.7-1.8-0.7-1.21.6-0.80.8-0.10.50.30.30.1-0.4
Intermittent access day 1 total infusions0.10.41.4-1.20.7-0.9-0.5-0.4-0.60.4-0.40.30.30.40.00.5-0.3-0.90.10.8-0.9-0.6-0.4
Intermittent access day 15 total infusions0.92.14.7-1.62.2-2.2-1.9-1.1-1.51.2-1.61.60.91.0-1.12.0-0.7-1.70.51.2-1.4-1.1-1.0
Intermittent access terminal intake (last 3 days)1.73.06.4-2.12.5-2.5-2.3-1.8-2.11.9-2.22.21.41.7-1.71.7-1.2-1.40.31.0-1.0-0.6-0.4
Intermittent access total infusions1.82.15.0-2.22.1-2.0-1.7-1.0-1.21.0-1.41.40.70.7-0.91.8-0.5-1.90.71.7-1.6-1.3-1.1
Intermittent access day 1 locomotion0.71.23.1-1.81.4-1.4-1.3-1.0-1.31.0-1.61.60.70.9-1.30.4-0.9-1.20.21.1-0.6-0.2-0.1
Intermittent access day 15 total locomotion0.82.95.9-1.82.0-2.4-2.1-1.7-2.42.0-2.42.41.61.9-2.01.1-1.8-0.9-0.40.6-0.5-0.00.2
Intermittent access total locomotion2.32.75.6-2.32.0-2.2-1.9-1.3-2.01.5-2.32.41.11.3-1.91.5-1.3-1.60.21.5-1.2-0.7-0.5
Intermittent access standard deviation0.00.21.0-0.30.1-0.30.10.3-0.50.2-0.60.8-0.40.2-0.40.7-0.0-0.60.00.6-1.0-0.7-0.4
Left kidney weight0.21.74.61.6-1.61.81.50.30.3-0.30.4-0.60.0-0.20.8-2.1-0.41.6-2.1-1.31.61.71.6
Right kidney weight0.32.15.22.1-2.12.32.11.21.2-1.21.4-1.5-1.0-1.01.4-2.20.51.0-1.4-0.80.91.00.9
Cocaine induced anxiety0.20.61.31.1-1.11.00.51.01.0-0.70.7-0.8-1.1-0.60.60.50.40.8-1.0-0.40.3-0.10.0
Post-drug Anxiety1.61.85.21.8-2.31.71.81.61.4-1.31.4-1.6-1.3-1.21.5-0.70.71.3-1.6-0.80.50.30.5
Baseline Anxiety0.81.32.8-0.0-1.10.91.61.31.3-1.61.2-1.3-0.9-1.71.5-0.91.2-1.10.51.1-1.0-0.7-0.8
Tail length0.10.41.41.2-0.61.10.90.10.5-0.40.4-0.4-0.1-0.50.3-1.20.40.50.0-0.60.70.60.4
Length with tail0.10.31.1-0.91.0-0.5-0.3-1.1-0.40.5-0.50.50.60.3-0.3-0.70.1-0.40.80.40.40.50.1
Length without tail0.31.66.8-2.61.7-1.4-1.3-0.9-0.90.7-1.51.50.10.5-1.10.80.1-1.71.22.0-0.9-0.6-0.8
Times rat made contact with spout0.10.10.5-0.1-0.20.10.3-0.2-0.30.2-0.40.40.30.1-0.6-0.7-0.40.2-0.3-0.10.40.50.5
Lifetime Intake1.41.85.1-2.21.9-1.8-1.4-0.8-1.00.8-1.21.20.50.6-0.71.6-0.3-1.90.81.7-1.7-1.3-1.1
Liver weight, left0.10.20.90.0-0.10.40.1-0.3-0.30.2-0.30.20.20.10.2-0.9-0.40.1-0.80.00.50.70.6
Liver weight, right0.30.51.4-0.40.3-0.2-0.2-1.0-0.70.9-0.20.11.00.90.2-1.0-0.80.9-0.6-0.41.01.11.2
Locomotor activity0.30.52.00.9-0.81.41.40.40.9-0.70.2-0.2-0.7-0.90.3-0.70.70.30.2-0.20.1-0.0-0.1
Locomotor testing distance0.10.31.80.7-0.70.81.40.20.1-0.0-0.40.3-0.1-0.2-0.0-0.2-0.20.8-1.1-0.60.10.10.4
Locomotor testing rearing1.03.66.71.3-1.91.82.42.52.5-2.51.6-1.6-2.6-2.61.80.62.4-0.90.41.2-1.7-1.8-1.7
Locomotion in novel chamber0.30.42.30.5-0.00.7-0.2-0.50.10.00.6-0.70.10.20.8-1.50.20.40.1-0.31.31.20.8
Locomotion in novel chamber post-restriction0.41.33.80.6-0.80.50.5-0.3-0.40.50.4-0.40.90.70.4-1.5-1.01.9-1.6-1.71.91.71.7
Fecal boli incidents, locomotor time 10.10.31.30.5-0.61.00.70.10.6-0.50.7-0.7-0.1-0.50.8-1.10.40.20.1-0.00.40.40.3
Change in fecal boli incidents, locomotor task0.70.72.3-0.30.10.5-0.30.70.7-0.70.1-0.1-1.5-0.80.41.31.3-1.10.81.2-0.9-1.1-1.2
Time >=10cm from walls, locomotor time 12.12.711.03.3-2.42.52.02.01.9-1.91.3-1.3-1.9-1.80.8-0.91.30.6-0.6-0.90.40.2-0.1
Bouts of movement, locomotor time 10.40.51.6-1.30.9-0.8-0.4-0.3-0.40.3-0.80.80.10.2-0.81.1-0.2-0.70.50.7-0.8-0.8-0.7
Total resting periods, locomotor time 10.70.92.8-1.71.4-1.2-0.8-0.8-0.80.8-1.21.10.40.5-0.91.2-0.5-0.80.50.8-0.7-0.7-0.6
Rest time, locomotor task time 12.03.28.6-2.12.9-1.7-2.7-2.8-2.22.2-2.12.01.92.0-1.70.2-1.5-0.60.60.30.80.80.4
Distance moved, locomotor task time 11.33.68.92.4-3.01.82.93.02.2-2.32.0-1.8-2.2-2.11.60.51.60.7-0.6-0.4-1.1-1.2-0.7
Vertical activity count, locomotor time 10.32.05.01.4-1.90.91.92.21.8-1.81.7-1.5-1.7-1.61.20.81.30.30.20.0-1.1-1.2-0.9
Time >=10cm from walls, locomotor time 20.51.35.12.2-1.61.81.41.21.4-1.41.0-0.9-1.3-1.30.8-1.10.90.3-0.3-0.30.40.30.1
Bouts of movement, locomotor time 20.10.31.10.6-1.10.80.80.70.4-0.50.1-0.3-0.5-0.40.0-0.70.10.3-0.9-0.20.30.40.4
Total resting periods, locomotor time 20.10.41.40.8-1.21.00.90.70.4-0.60.1-0.3-0.5-0.4-0.0-0.90.10.4-1.0-0.30.40.50.5
Rest time, locomotor task time 20.30.51.7-0.71.0-0.6-1.3-0.9-0.80.7-0.80.60.70.8-0.9-0.3-0.6-0.40.40.10.60.70.4
Distance moved, locomotor task time 20.70.92.61.1-1.30.61.61.41.1-1.01.1-0.9-0.8-1.01.00.50.60.4-0.1-0.2-0.8-0.9-0.6
Vertical activity count, locomotor time 20.10.20.8-0.2-0.0-0.70.4-0.3-0.50.5-0.10.20.70.5-0.2-0.1-0.90.7-0.3-0.50.10.20.4
Light reinforcement 10.10.31.10.7-0.90.81.10.70.4-0.60.3-0.2-0.3-0.60.1-0.50.30.1-0.0-0.0-0.2-0.1-0.0
Light reinforcement 20.40.83.50.1-0.10.20.00.91.1-1.21.4-1.4-0.8-0.80.7-0.01.0-0.91.90.7-0.6-0.6-1.0
Bone: marrow area0.10.20.7-0.90.7-0.8-0.5-0.3-0.0-0.00.1-0.10.1-0.00.20.10.2-0.80.90.8-0.4-0.3-0.5
Bone: maximum diameter0.20.42.20.8-0.81.10.70.30.4-0.60.4-0.5-0.3-0.60.3-1.50.2-0.1-0.00.00.30.50.4
Bone: maximum force0.50.92.8-1.21.3-1.7-1.3-1.2-1.41.2-0.70.61.31.3-0.60.3-1.1-0.1-0.1-0.10.20.30.3
Bone: maximum moment0.50.92.7-1.41.4-1.6-1.3-1.1-1.31.1-0.60.61.11.1-0.30.4-0.9-0.30.00.2-0.00.10.1
Mean time between licks in bursts0.10.41.4-0.70.6-0.5-0.3-0.7-0.60.4-1.11.10.70.2-1.2-0.7-0.4-0.60.70.60.10.30.1
Mean num. licks in bursts0.10.42.00.1-0.4-0.2-0.10.3-0.80.4-1.11.20.00.4-1.40.5-0.70.2-0.9-0.5-0.10.10.3
Cd content in liver1.21.44.80.00.1-0.0-0.4-0.8-1.41.3-2.22.20.70.9-1.90.3-1.20.9-1.6-0.90.80.81.1
Co content in liver0.91.02.5-1.21.3-1.1-1.0-1.5-1.11.2-1.61.51.10.9-1.40.2-0.7-0.1-0.10.30.30.30.3
Cu content in liver0.70.83.3-1.61.2-1.8-0.9-0.5-0.80.5-0.50.50.60.7-0.80.8-0.5-0.81.10.7-0.7-0.6-0.6
Fe content in liver1.01.23.9-1.51.6-2.0-1.7-1.2-1.41.4-0.80.71.01.5-0.71.1-1.1-0.10.1-0.10.0-0.00.0
K content in liver1.71.65.71.4-1.31.11.10.50.7-0.62.0-2.10.3-0.21.9-2.4-0.21.1-0.7-1.11.21.31.2
Mg content in liver0.30.31.00.7-0.80.30.50.60.5-0.51.0-1.0-0.1-0.30.9-0.70.10.3-0.3-0.30.10.20.2
Mn content in liver0.10.10.5-0.2-0.10.10.60.1-0.0-0.10.3-0.3-0.1-0.10.7-0.10.2-0.2-0.00.2-0.5-0.3-0.2
Na content in liver1.21.44.41.1-1.11.51.01.21.5-1.32.1-2.1-1.1-1.02.1-0.51.00.20.3-0.2-0.2-0.3-0.4
Rb content in liver0.20.20.9-0.8-0.1-0.10.60.40.0-0.30.2-0.1-0.3-0.20.30.30.3-0.50.70.7-0.9-0.7-0.6
Se content in liver1.41.64.0-1.51.5-2.0-1.5-1.3-1.81.7-1.41.41.21.7-1.31.0-1.40.1-0.3-0.40.00.10.3
Sr content in liver0.80.72.31.5-1.21.10.60.40.5-0.50.6-0.7-0.0-0.40.3-1.5-0.20.7-1.0-0.71.01.11.0
Zn content in liver0.91.03.5-0.2-0.3-0.5-0.0-0.4-1.30.8-1.61.61.10.8-1.9-1.0-1.30.5-0.8-0.60.81.11.1
Bone: minimum diameter0.51.02.4-1.41.2-1.6-1.5-1.1-1.51.2-1.21.21.01.0-1.10.4-1.0-0.5-0.40.30.10.20.2
Time in familiar zone, hab. session 10.20.31.5-0.10.00.10.4-0.2-0.50.4-1.21.20.20.2-0.80.7-0.20.3-0.6-0.3-0.0-0.10.1
Time in novel zone, hab. session 10.10.10.40.5-0.30.1-0.20.30.2-0.20.6-0.6-0.20.00.2-0.4-0.10.1-0.1-0.20.20.20.2
Total zone transitions, hab. session 10.60.82.40.7-1.11.51.01.11.2-1.2-0.10.1-1.3-1.5-0.0-0.21.2-0.7-0.30.9-0.5-0.4-0.5
Total locomotion distance, hab. session 10.30.41.10.6-0.30.60.20.60.9-0.80.3-0.3-1.0-1.00.20.21.0-0.6-0.00.5-0.2-0.4-0.6
Locomotion velocity, hab. session 10.30.41.00.8-0.50.80.30.61.0-0.90.6-0.6-0.9-0.90.4-0.20.9-0.3-0.10.30.0-0.1-0.4
Time in familiar zone, hab. session 20.10.10.3-0.00.30.1-0.1-0.5-0.30.40.0-0.00.50.30.2-0.3-0.30.30.2-0.50.40.40.3
Time in novel zone, hab. session 20.10.10.60.4-0.4-0.20.20.4-0.0-0.0-0.30.3-0.4-0.0-0.50.7-0.10.2-0.8-0.2-0.3-0.3-0.1
Total zone transitions, hab. session 20.60.73.91.1-1.31.11.30.70.7-0.90.4-0.6-0.2-0.90.1-2.00.2-0.1-0.20.20.30.70.6
Total locomotion distance, hab. session 20.70.92.81.5-1.41.11.60.91.1-1.11.0-1.1-0.3-1.00.5-1.70.50.2-0.1-0.30.30.50.4
Locomotion velocity, hab. session 20.71.02.91.4-1.51.11.51.01.2-1.31.0-1.2-0.5-1.20.5-1.70.60.00.0-0.10.20.50.3
Novel to familiar place preference ratio0.10.10.4-0.30.1-0.2-0.1-0.10.10.10.4-0.30.00.10.60.40.10.3-0.6-0.10.1-0.1-0.1
Novelty place preference0.20.21.1-0.20.2-0.4-0.4-0.4-0.40.50.0-0.00.40.50.30.3-0.40.7-1.1-0.60.50.30.4
Time in novel zone, NPP test0.20.21.2-0.40.3-0.4-0.5-0.4-0.50.6-0.30.30.30.50.10.7-0.30.5-1.1-0.40.30.10.2
Total zone transitions, NPP test0.60.92.01.1-1.00.40.8-0.0-0.70.3-1.01.00.60.3-1.3-1.3-0.90.9-1.4-1.00.81.11.3
Total locomotion distance, NPP test0.20.31.00.5-0.1-0.30.1-0.4-0.50.4-0.70.60.50.3-1.0-0.6-0.50.4-0.6-0.60.50.70.7
Locomotion velocity, NPP test0.30.41.40.9-0.4-0.10.4-0.3-0.40.3-0.30.30.60.3-0.7-1.2-0.60.7-0.6-0.90.80.90.9
Intraocular pressure0.30.53.3-0.20.10.20.1-0.1-0.40.1-1.71.6-0.3-0.3-1.80.10.4-0.70.40.4-0.3-0.1-0.2
Delta distance traveled before/after self-admin2.02.210.7-1.61.1-0.5-1.10.60.5-0.3-0.20.2-1.6-0.50.33.31.3-1.80.62.0-2.2-2.5-2.2
Delta ambulatory time before/after self-admin0.81.46.6-1.61.0-0.6-0.90.20.20.0-0.50.5-1.1-0.1-0.12.60.7-1.30.21.6-1.7-1.9-1.6
Parametrial fat weight0.00.10.5-0.2-0.30.30.30.2-0.2-0.2-0.20.2-0.00.0-0.6-0.7-0.3-0.30.30.1-0.20.10.2
Pavlov. Cond. lever latency0.50.61.20.20.3-0.5-0.6-0.8-0.80.8-0.40.41.00.9-0.6-0.8-1.00.8-0.3-1.11.11.10.9
Pavlov. Cond. magazine entry latency0.40.52.30.7-0.70.81.40.30.6-0.30.8-0.8-0.0-0.41.5-0.30.30.9-1.0-0.40.20.00.3
Pavlov. Cond. change in total contacts0.50.52.40.0-0.10.10.50.40.9-0.51.3-1.4-0.6-0.41.60.50.70.10.10.4-0.4-0.7-0.5
Pavlov. Cond. index score0.20.31.1-0.1-0.20.30.70.30.6-0.40.5-0.5-0.4-0.51.10.50.6-0.1-0.20.6-0.6-0.7-0.5
Pavlov. Cond. latency score0.20.20.60.1-0.40.50.80.40.5-0.30.3-0.3-0.4-0.50.70.40.50.0-0.50.4-0.5-0.5-0.3
Pavlov. Cond. lever contacts0.20.30.7-0.3-0.10.00.30.40.5-0.40.3-0.4-0.6-0.50.60.80.6-0.40.10.8-0.8-0.8-0.6
Pavlov. Cond. magazine entry number0.30.42.3-0.40.5-0.5-1.2-0.3-0.60.3-0.80.80.30.4-1.5-0.2-0.4-0.70.70.20.10.30.1
Pavlov. Cond. intertrial magazine entries0.50.51.8-1.10.2-0.5-0.30.60.2-0.50.2-0.2-0.6-0.40.30.80.5-1.30.41.4-1.2-1.0-1.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.6-0.0-0.20.30.80.40.7-0.50.8-0.8-0.5-0.61.30.40.7-0.1-0.10.5-0.6-0.7-0.5
Pavlov. Cond. response bias0.40.52.90.5-0.50.51.10.40.9-0.51.2-1.1-0.4-0.51.70.20.60.6-0.5-0.1-0.2-0.4-0.2
Pavlov. Cond. lever latency0.00.00.1-0.20.0-0.3-0.20.20.00.00.3-0.3-0.30.3-0.10.40.00.20.3-0.2-0.1-0.2-0.1
Pavlov. Cond. magazine entry latency0.20.30.90.9-0.60.70.40.1-0.2-0.0-0.60.50.1-0.1-0.4-0.7-0.30.4-1.0-0.50.70.80.7
Pavlov. Cond. change in total contacts0.30.62.91.2-1.00.91.10.1-0.20.1-0.30.20.4-0.10.2-1.0-0.60.9-1.7-0.80.70.91.0
Pavlov. Cond. index score0.10.21.10.6-0.50.50.4-0.0-0.30.1-0.60.50.3-0.2-0.3-0.3-0.30.3-1.1-0.20.40.50.5
Pavlov. Cond. latency score0.20.41.60.9-0.60.50.4-0.1-0.40.2-0.60.40.50.0-0.3-0.7-0.60.5-1.3-0.60.80.90.9
Pavlov. Cond. lever contacts0.00.10.30.2-0.10.40.3-0.1-0.10.0-0.50.40.2-0.30.0-0.2-0.0-0.1-0.60.20.10.20.1
Pavlov. Cond. magazine entry number0.60.83.0-1.51.1-0.8-1.0-0.30.3-0.10.4-0.3-0.3-0.00.10.90.7-1.01.71.1-0.9-1.0-1.1
Pavlov. Cond. intertrial magazine entries0.20.41.30.3-0.50.30.41.00.8-0.80.6-0.4-0.9-0.6-0.10.40.8-0.51.10.3-0.9-0.9-0.8
Pavlov. Cond. lever-magazine prob. diff.0.10.21.30.7-0.60.50.50.1-0.20.0-0.50.40.2-0.2-0.2-0.3-0.30.3-1.1-0.30.40.50.5
Pavlov. Cond. response bias0.10.10.40.2-0.10.30.5-0.1-0.20.1-0.60.60.2-0.3-0.1-0.1-0.1-0.1-0.50.1-0.00.10.1
Time in closed arm before self-admin0.10.10.7-0.00.2-0.0-0.40.20.3-0.30.6-0.8-0.6-0.10.60.40.1-0.30.10.4-0.1-0.2-0.3
Time in closed arm after self-admin1.11.33.40.20.7-1.1-0.9-1.3-1.41.5-0.50.31.71.5-0.6-0.2-1.81.2-1.0-1.41.11.01.2
Time in open arm before self-admin0.60.82.7-1.41.0-0.9-0.1-0.9-0.90.9-1.51.60.90.6-1.20.6-0.4-0.40.40.4-0.7-0.4-0.2
Time in open arm after self-admin0.30.31.5-0.90.30.2-0.1-0.00.5-0.40.3-0.1-0.3-0.50.5-0.30.9-0.81.21.0-0.3-0.2-0.5
Bone: periosteal estimation0.00.10.2-0.40.4-0.4-0.3-0.3-0.10.10.1-0.20.20.00.3-0.2-0.0-0.50.30.4-0.1-0.0-0.1
Bone: periosteal perimeter0.30.61.50.7-1.01.10.91.00.9-1.10.6-0.6-0.9-1.20.5-0.60.8-0.60.10.6-0.4-0.2-0.3
Bone: post-yield work0.10.10.4-0.20.3-0.2-0.0-0.5-0.50.4-0.20.30.40.2-0.0-0.6-0.3-0.2-0.10.10.10.30.3
Progressive ratio test 1 active lever presses0.61.13.8-0.90.4-0.6-0.00.80.6-0.70.1-0.1-0.8-0.80.21.40.7-1.70.71.7-2.0-1.7-1.6
Progressive ratio test 1 breakpoint0.61.03.6-1.00.4-0.7-0.10.60.5-0.60.0-0.1-0.6-0.70.11.30.6-1.70.71.6-1.9-1.6-1.5
Progressive ratio test 1 inactive lever presses0.00.10.3-0.2-0.0-0.60.20.30.1-0.20.2-0.2-0.2-0.10.30.2-0.2-0.3-0.20.2-0.5-0.4-0.3
Progressive ratio test 2 active lever presses1.31.86.7-2.62.0-2.0-1.7-0.9-1.00.8-1.11.00.60.7-0.81.6-0.4-1.80.81.6-1.3-1.1-1.0
Progressive ratio test 2 breakpoint1.52.07.4-2.72.1-2.1-1.7-1.0-1.10.9-1.11.00.70.7-0.81.5-0.5-1.80.91.6-1.3-1.0-1.0
Progressive ratio test 2 inactive lever presses0.20.71.7-1.21.2-1.3-1.1-0.6-0.90.6-0.90.80.30.6-0.40.8-0.6-1.2-0.01.0-0.8-0.5-0.5
Incentive Sensitization - Responses0.61.86.2-2.52.1-1.9-1.9-1.5-1.51.3-1.41.30.91.1-0.91.0-0.7-1.20.61.2-0.5-0.3-0.3
Incentive Sensitization - Breakpoint0.92.06.5-2.52.2-1.9-2.1-1.7-1.61.5-1.51.41.01.3-1.11.0-0.9-1.20.51.1-0.4-0.2-0.3
Sum of active levers in priming session hrs 5-60.30.31.2-1.10.8-0.8-0.4-0.6-0.60.5-0.30.30.60.4-0.2-0.0-0.1-0.60.70.8-0.4-0.2-0.1
Progressive ratio0.10.31.2-0.50.6-0.1-1.0-0.8-0.50.4-0.40.40.30.4-0.3-1.1-0.2-0.50.40.70.60.80.5
Food seeking constrained by brief footshock1.21.54.3-1.61.9-1.6-1.3-0.8-0.60.4-1.11.00.30.2-1.10.70.0-2.11.81.7-1.1-0.8-1.1
Seeking ratio, punishment vs. effort0.20.42.3-0.40.5-1.1-0.10.0-0.40.3-0.60.60.10.3-0.61.5-0.4-0.20.0-0.1-0.8-0.9-0.7
Retroperitoneal fat weight0.00.00.20.10.1-0.1-0.20.30.0-0.20.2-0.3-0.1-0.0-0.10.2-0.1-0.50.20.1-0.4-0.2-0.3
Reaction time number correct0.10.41.6-1.31.0-1.0-0.8-0.4-0.30.3-0.20.20.10.3-0.10.4-0.1-0.70.70.8-0.5-0.5-0.5
Reaction time mean minus median0.10.51.40.7-0.80.30.51.20.7-0.70.7-0.6-0.9-0.60.91.20.70.1-0.3-0.2-0.6-0.8-0.6
Reaction time mean minus median AUC0.10.42.00.5-0.6-0.10.51.00.4-0.50.5-0.4-0.6-0.40.71.40.50.2-0.3-0.3-0.7-0.9-0.7
Reaction time num false alarms1.83.05.4-0.21.3-1.3-1.5-2.3-2.12.3-1.71.62.12.2-1.6-0.9-2.21.4-1.1-1.62.02.01.9
Reaction time num false alarms AUC1.22.74.70.01.0-1.0-1.1-2.2-1.92.1-1.51.52.02.0-1.4-1.0-2.01.5-1.1-1.72.01.91.9
Reaction time trials correct on left0.10.41.6-1.31.0-1.0-0.8-0.4-0.30.3-0.20.20.10.3-0.10.4-0.1-0.70.70.8-0.5-0.5-0.5
Reaction time trials on left0.10.31.4-1.20.9-1.0-0.7-0.4-0.30.3-0.10.10.00.3-0.00.4-0.0-0.70.60.8-0.4-0.4-0.5
Reaction time mean0.81.85.11.2-1.71.31.22.31.5-1.71.1-0.9-2.0-1.51.01.21.7-0.30.20.2-1.2-1.3-1.1
Reaction time mean AUC0.61.54.40.9-1.51.01.22.11.3-1.51.0-0.8-1.7-1.40.91.41.5-0.30.40.2-1.3-1.4-1.2
Median of all reaction times1.11.74.81.0-1.61.21.22.21.4-1.60.9-0.8-2.0-1.50.71.21.7-0.50.40.4-1.2-1.3-1.1
Reaction time omissions0.81.34.92.2-1.91.31.61.10.7-0.70.7-0.7-0.4-0.50.6-0.80.31.5-1.1-1.60.70.60.8
Reaction time false alarm rate1.52.14.01.00.2-0.2-0.4-1.5-1.41.5-1.11.11.61.5-1.1-1.1-1.71.8-1.5-2.02.01.92.0
Reaction time premature initiation rate0.50.73.21.5-1.61.40.50.90.1-0.4-0.10.1-0.7-0.4-0.2-0.7-0.10.5-1.8-0.50.50.60.8
Reaction time premature initiations0.10.41.51.0-1.21.10.40.90.3-0.60.2-0.2-0.9-0.50.1-0.50.20.1-1.1-0.00.20.30.4
Std. dev. reaction times0.30.93.11.8-1.60.91.11.40.5-0.60.4-0.3-0.9-0.40.70.70.41.1-1.3-1.30.0-0.10.2
Reaction time trials completed0.10.31.4-1.20.9-1.0-0.7-0.4-0.30.3-0.10.10.00.3-0.00.4-0.0-0.70.60.8-0.4-0.4-0.5
Reaction time trials AUC0.10.31.4-1.20.9-1.0-0.8-0.5-0.40.4-0.20.20.20.4-0.10.4-0.2-0.60.50.7-0.4-0.3-0.4
Run reversals in cocaine runway, females1.11.24.72.2-1.21.51.20.50.9-0.81.2-1.2-0.5-0.61.3-1.80.40.9-0.3-0.81.01.00.8
Run reversals in cocaine runway, males1.01.12.91.3-0.60.20.6-0.4-0.60.50.1-0.21.40.60.0-1.6-1.51.4-1.0-1.71.31.41.4
Latency to leave start box in cocaine runway1.62.25.31.9-2.32.12.02.01.8-1.81.8-1.7-1.5-1.51.5-0.81.30.6-0.6-0.2-0.0-0.1-0.0
Latency to leave start box in cocaine runway, F0.60.82.90.9-1.71.51.21.20.9-0.80.7-0.7-0.9-0.70.7-0.30.70.8-1.0-0.40.20.10.4
Latency to leave start box in cocaine runway, M2.72.65.51.6-1.31.41.52.02.3-2.22.3-2.2-1.8-1.91.8-0.21.7-0.60.80.7-0.9-1.0-1.3
Std. dev. time between licks in bursts0.91.73.50.5-0.10.00.1-1.0-1.51.2-1.81.91.51.1-1.8-1.1-1.81.2-1.6-1.21.21.51.6
Total sessions with >9 infusions0.81.03.7-1.20.0-0.20.20.90.4-0.70.1-0.1-0.9-0.70.30.91.0-1.70.61.7-1.9-1.5-1.3
Short access day 1 total inactive lever presses1.22.45.00.6-1.41.21.52.02.0-2.21.7-1.7-1.8-2.11.8-0.61.9-1.30.71.4-1.3-1.0-1.2
Short access day 10 total inactive lever presses0.21.64.72.0-2.11.61.81.00.4-0.50.7-0.5-0.5-0.30.9-1.6-0.41.6-2.2-1.20.80.91.3
Short access day 1 total infusions0.61.23.2-1.3-0.2-0.00.51.10.8-1.01.0-1.0-1.0-0.91.30.61.0-1.50.61.6-1.8-1.4-1.3
Short access day 10 total infusions0.71.12.3-1.31.3-1.4-1.5-0.8-1.31.1-1.41.40.51.0-1.21.3-0.9-0.9-0.40.7-0.7-0.5-0.2
Short access total infusions0.50.72.8-1.40.5-0.8-0.30.5-0.1-0.3-0.10.1-0.4-0.20.21.10.3-1.50.41.4-1.7-1.3-1.1
Short access day 1 locomotion0.91.53.5-1.91.6-1.7-1.2-0.8-1.20.8-1.41.40.70.8-1.11.0-0.4-1.71.01.4-1.4-0.9-0.7
Short access day 10 total locomotion0.10.31.50.0-0.40.00.10.4-0.60.2-1.11.2-0.10.2-1.00.3-0.7-0.3-1.00.4-0.6-0.20.2
Short access total locomotion0.81.14.7-0.5-0.2-0.10.21.20.2-0.8-0.50.6-1.0-0.8-0.51.30.6-1.80.51.7-2.2-1.7-1.4
One hour access (0.3 mA shock)2.42.97.7-2.42.6-2.7-2.3-1.2-1.61.4-1.51.41.01.3-1.32.8-0.8-1.61.01.2-1.5-1.4-1.2
Compulsive drug intake0.81.12.81.7-1.41.30.61.61.3-1.11.0-1.0-1.6-0.80.81.20.80.8-1.1-0.50.0-0.4-0.3
One hour access (shock baseline)1.23.28.6-2.92.9-2.9-2.0-1.8-1.81.6-1.41.41.71.3-0.91.7-0.9-1.81.51.4-1.4-1.1-1.0
Social response proportion2.12.65.11.9-2.02.21.72.02.2-2.21.9-1.9-1.5-2.21.6-1.01.8-0.50.70.6-0.6-0.5-0.6
Social responses0.71.03.21.8-1.61.51.50.70.5-0.40.5-0.5-0.1-0.40.5-1.00.01.3-1.3-1.10.70.71.0
Social time0.30.41.70.8-1.31.00.60.80.1-0.5-0.40.3-0.5-0.4-0.7-1.1-0.10.1-0.4-0.10.40.70.7
Soleus weight0.72.04.6-2.02.2-1.9-2.2-1.6-1.51.5-1.81.80.81.4-1.61.4-0.7-0.70.60.5-0.1-0.1-0.3
Bone: stiffness0.61.03.1-0.81.2-1.8-1.0-1.4-1.41.3-0.50.51.71.4-0.5-0.4-1.40.30.1-0.60.60.70.6
Tibialis anterior weight0.72.57.7-1.60.9-0.5-0.90.81.0-1.20.5-0.5-1.4-1.20.21.31.7-2.82.42.7-2.0-1.8-2.2
Time to tail flick, vehicle, before self-admin0.70.92.61.1-1.61.21.31.61.1-1.40.8-0.9-1.3-1.20.2-0.40.7-0.1-0.40.0-0.3-0.2-0.3
Time to tail flick, vehicle, after self-admin0.81.53.2-0.50.8-0.8-0.6-1.8-1.51.5-0.70.61.81.5-0.3-1.5-1.61.0-0.5-0.91.61.71.6
Time to tail flick, test, before self-admin0.20.21.0-0.40.6-1.0-0.3-0.5-0.60.6-0.40.30.80.5-0.10.7-0.4-0.00.0-0.1-0.5-0.3-0.1
Time to tail flick, test, after self-admin0.50.52.30.40.1-0.40.1-0.20.2-0.01.5-1.51.00.21.5-0.6-0.50.7-0.3-0.90.40.30.2
Delta time to tail flick, vehicle, before/after SA0.50.61.20.00.2-0.10.0-0.9-0.60.80.0-0.01.00.80.7-0.9-0.81.1-0.6-0.91.01.01.1
Delta time to tail flick, test, before/after SA0.70.83.20.6-0.60.90.70.71.2-1.01.8-1.7-0.5-0.81.7-0.90.70.30.4-0.20.40.2-0.2
Tibia length0.30.93.10.9-1.41.21.71.40.9-1.20.6-0.6-1.3-1.10.7-0.40.7-0.2-0.00.3-0.7-0.5-0.3
Ambulatory time before self-admin0.20.52.11.4-1.20.80.90.40.0-0.30.10.00.3-0.2-0.3-1.2-0.20.7-0.2-0.80.60.80.8
Ambulatory time after self-admin0.10.21.2-0.1-0.20.1-0.20.60.1-0.2-0.30.3-0.6-0.2-0.41.10.3-0.5-0.10.5-0.8-0.8-0.6
Bone: tissue strength0.80.81.8-0.4-0.10.60.90.61.0-1.01.0-1.0-0.5-1.01.3-0.31.1-0.91.31.0-0.9-0.8-1.0
Total heroin consumption0.20.31.6-0.60.5-0.1-0.4-0.30.1-0.10.7-0.8-0.00.00.7-0.80.3-0.61.30.60.10.2-0.1
Bone: trabecular number0.81.44.3-0.5-0.10.21.31.01.3-1.40.9-0.8-0.7-1.41.10.11.5-1.32.11.4-1.5-1.4-1.6
Bone: trabecular spacing0.20.31.10.00.3-0.0-0.9-0.5-0.60.6-0.80.80.00.6-1.10.3-0.30.2-0.2-0.30.50.30.4
Bone: trabecular thickness1.01.43.8-1.50.7-0.50.30.40.8-0.90.7-0.7-0.5-1.00.90.51.2-1.72.01.9-1.6-1.4-1.6
Bone: trabecular tissue density2.03.58.50.8-1.92.11.62.72.2-2.51.5-1.5-2.9-2.41.40.82.1-1.40.71.5-1.9-1.9-1.7
Water consumed over 24 hours0.10.10.2-0.40.3-0.3-0.3-0.4-0.40.3-0.10.10.30.4-0.2-0.5-0.40.1-0.0-0.10.40.50.4
Number of responses in last shaping day2.02.510.1-3.22.1-2.6-1.4-1.3-1.91.5-1.71.71.41.4-1.21.3-1.2-1.40.61.2-1.3-0.8-0.5