Hrh1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL isoform ratio XM_039107019.1 0.03 0.02 4.3e-03 0 0.01 0.01 0.01 1.9e-01 1.0e-02 2.4e-02 6.0e-02
2 PL isoform ratio NM_017018.2 0.03 0.02 5.1e-03 0 0.01 0.01 0.01 1.9e-01 9.4e-03 2.4e-02 5.8e-02
3 NAcc mRNA stability Hrh1 0.03 0.01 2.9e-04 0.02 0.03 0.02 0.02 3.5e-03 5.3e-04 2.0e-03 4.1e-03
4 PL mRNA stability Hrh1 0.04 0.02 1.3e-04 0.04 0.04 0.04 0.02 9.5e-05 8.9e-05 7.9e-05 1.7e-03
5 BLA mRNA stability Hrh1 0.06 0.04 5.9e-03 0 0.04 0.02 0.02 2.1e-01 5.5e-03 2.5e-02 3.8e-02
6 PL intron excision ratio chr4_147565025_147645960 0.04 0.03 9.9e-05 0.03 0.03 0.04 0.03 7.4e-04 6.4e-04 5.5e-05 2.4e-04
7 PL alternative TSS NM_017018.2 0.05 0.04 5.0e-04 0.01 0.02 0.01 0.01 1.3e-02 3.0e-03 2.4e-02 1.8e-02
8 Brain mRNA stability Hrh1 0.08 0.04 5.0e-09 0.09 0.09 0.08 0.08 6.4e-09 1.2e-08 4.7e-08 3.8e-08
9 PL alternative TSS XM_039107019.1 0.05 0.04 3.3e-04 0.01 0.02 0.01 0.02 8.7e-03 1.4e-03 2.1e-02 6.7e-03
10 Brain alternative polyA XM_039107019.1 0.04 0.02 9.2e-03 0.01 0.01 0.01 0.01 1.9e-02 1.7e-02 7.7e-02 1.4e-02
11 Brain alternative polyA NM_017018.2 0.04 0.02 9.1e-03 0.03 0.01 0.01 0.01 5.6e-04 1.7e-02 4.0e-02 1.5e-02
12 NAcc isoform ratio NM_017018.2 0.03 0.02 7.0e-04 0.03 0.01 0.02 0.02 2.0e-04 1.2e-02 1.9e-03 2.6e-03
13 NAcc alternative polyA XM_039107019.1 0.04 0.02 1.9e-04 0.04 0.02 0.03 0.04 2.2e-05 9.1e-04 2.9e-04 6.1e-05
14 NAcc alternative polyA NM_017018.2 0.04 0.02 1.2e-04 0.04 0.02 0.03 0.04 1.2e-05 9.0e-04 1.0e-04 3.9e-05
15 NAcc isoform ratio XM_039107019.1 0.03 0.02 6.4e-04 0.03 0.01 0.02 0.02 2.1e-04 1.1e-02 2.1e-03 2.0e-03
16 PL alternative polyA NM_017018.2 0.04 0.02 1.8e-03 0.03 0.02 0.03 0.03 1.5e-04 1.6e-03 6.5e-04 4.3e-04
17 PL alternative polyA XM_039107019.1 0.04 0.02 2.2e-03 0.03 0.02 0.02 0.02 2.2e-04 2.0e-03 1.3e-03 1.1e-03
18 NAcc gene expression Hrh1 0.18 0.06 0.0e+00 0.2 0.19 0.2 0.2 3.1e-22 4.6e-21 2.2e-22 7.2e-23
19 PL intron excision ratio chr4_147565461_147645960 0.03 0.02 3.1e-03 0.02 0.01 0 0.01 1.4e-03 4.1e-02 1.0e-01 1.6e-02
20 BLA gene expression Hrh1 0.3 0.1 1.2e-13 0.25 0.24 0.24 0.26 2.2e-13 2.3e-13 2.8e-13 6.2e-14
21 Adipose gene expression Hrh1 0.06 0.04 1.1e-03 0.03 0.03 0.02 0.03 3.8e-04 2.4e-04 2.9e-03 6.1e-04
22 LHb gene expression Hrh1 0.26 0.13 1.1e-03 -0 0.04 0.04 0.01 4.4e-01 3.6e-02 3.2e-02 2.3e-01
23 OFC gene expression Hrh1 0.35 0.12 1.3e-06 0.15 0.23 0.23 0.24 2.6e-04 4.0e-06 2.8e-06 2.5e-06
24 IL gene expression Hrh1 0.42 0.13 1.8e-06 0.13 0.2 0.19 0.2 5.0e-04 1.2e-05 2.1e-05 1.6e-05
25 Brain gene expression Hrh1 0.43 0.1 0.0e+00 0.26 0.4 0.4 0.4 4.7e-24 3.0e-39 2.9e-39 3.0e-39
26 PL gene expression Hrh1 0.38 0.09 0.0e+00 0.24 0.4 0.42 0.42 3.2e-26 5.9e-47 1.3e-50 2.4e-49

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.71.26.7-1.01.01.00.3-0.21.3-1.1-0.01.0-1.0-1.0-0.90.9-0.90.9-1.01.0-0.4-0.9-0.90.32.6-0.9-1.41.51.7
Area under the delay curve0.20.20.7-0.30.4-0.3-0.0-0.30.6-0.50.10.5-0.5-0.5-0.30.3-0.30.3-0.30.3-0.6-0.4-0.6-0.40.8-0.6-0.10.30.4
BMI with tail0.61.95.1-1.81.81.8-2.01.7-2.01.9-2.3-1.9-0.9-0.9-1.01.0-1.01.0-1.01.01.41.71.30.5-0.9-0.70.5-0.2-0.5
BMI without tail0.81.74.70.1-0.10.2-0.40.8-1.61.4-1.2-1.41.11.11.2-1.21.2-1.21.2-1.21.82.21.2-1.4-2.01.01.9-1.5-1.7
Body weight0.31.13.5-1.71.71.6-1.11.5-1.41.4-1.9-1.5-0.6-0.6-0.40.4-0.40.4-0.40.41.31.50.7-0.3-0.1-0.30.6-0.2-0.3
Weight adjusted by age0.20.20.8-0.20.2-0.30.1-0.40.8-0.60.30.6-0.2-0.2-0.20.2-0.20.2-0.30.3-0.7-0.8-0.3-0.20.9-0.4-0.40.60.5
Bone surface0.50.83.9-0.30.40.30.9-0.61.3-1.20.31.1-0.8-0.8-0.70.7-0.70.7-0.70.7-0.7-1.0-0.90.22.0-0.3-1.11.21.4
Bone volume0.40.73.9-0.70.70.90.30.00.9-0.7-0.30.7-0.8-0.8-0.70.7-0.70.7-0.70.7-0.2-0.6-0.50.42.0-0.4-1.11.11.3
Breakpoint value in progressive ratio session2.02.27.9-2.82.82.4-1.82.2-1.21.7-2.5-1.7-0.5-0.5-0.80.8-0.80.8-0.70.71.71.71.5-0.70.9-0.90.6-0.2-0.3
Number of licking bursts0.40.51.10.6-0.5-0.40.6-0.70.5-0.60.50.50.80.81.0-1.01.0-1.01.0-1.00.20.3-0.4-1.0-0.3-0.00.5-0.4-0.1
Context. condit. distance diff. score2.02.47.5-1.51.52.0-1.82.3-2.62.7-2.2-2.7-0.6-0.6-0.40.4-0.40.4-0.40.42.01.92.10.8-1.4-0.10.7-0.6-1.0
Locomotion velocity, session 10.30.30.70.3-0.3-0.50.20.3-0.40.40.2-0.50.80.80.7-0.70.7-0.70.7-0.70.40.30.6-0.7-0.40.50.7-0.7-0.7
Locomotion distance, session 10.70.91.80.9-0.9-0.90.9-0.40.1-0.00.6-0.01.31.31.3-1.31.3-1.31.2-1.20.50.40.3-1.3-0.90.80.9-0.8-0.8
Locomotion velocity, session 20.50.61.81.0-1.0-1.31.2-0.70.9-0.91.20.80.80.80.7-0.70.7-0.70.6-0.6-0.4-0.5-0.2-1.0-0.00.70.3-0.3-0.2
Locomotion distance, session 21.42.04.61.4-1.4-1.41.5-0.80.7-0.61.10.52.02.01.9-1.91.9-1.91.9-1.90.40.30.1-2.1-0.91.01.3-1.1-1.0
Locomotion velocity, session 30.70.81.90.2-0.2-0.70.6-1.21.3-1.20.51.2-0.9-0.9-0.90.9-0.90.9-0.90.9-1.1-1.4-1.00.40.5-0.6-1.01.01.0
Locomotion distance, session 30.50.61.70.1-0.0-0.60.8-1.11.3-1.10.61.1-0.3-0.3-0.40.4-0.40.4-0.40.4-1.1-1.2-1.0-0.20.9-0.6-0.81.00.9
Stereotopy head waving bouts, day 31.21.42.61.5-1.5-1.60.9-0.40.0-0.30.70.21.51.51.5-1.51.5-1.51.4-1.40.40.40.4-1.5-1.01.31.4-1.4-1.3
Stereotopy head waving duration, day 31.31.53.21.3-1.4-1.50.60.1-0.70.50.4-0.61.31.31.4-1.41.4-1.41.3-1.30.70.71.2-1.3-1.71.51.6-1.6-1.8
Locomotion velocity, session 70.50.51.60.1-0.1-0.10.8-0.81.1-0.80.80.9-0.7-0.7-0.50.5-0.50.5-0.40.4-0.9-1.3-0.80.60.5-0.5-1.21.11.0
Locomotion distance, session 71.11.53.1-1.41.41.2-0.30.10.5-0.1-0.10.1-1.7-1.7-1.51.5-1.51.5-1.41.4-0.7-0.9-0.41.11.4-1.2-1.51.81.5
Stereotopy head waving bouts, day 70.80.92.41.5-1.5-1.51.3-0.91.0-1.21.41.10.80.80.8-0.80.8-0.80.9-0.9-0.6-0.7-0.5-0.6-0.11.00.1-0.4-0.2
Stereotopy head waving duration, day 71.21.53.61.9-1.9-1.81.5-0.70.7-0.91.40.81.31.31.3-1.31.3-1.31.3-1.3-0.3-0.3-0.1-1.1-0.51.60.7-0.9-0.9
Locomotion velocity, session 80.91.02.00.4-0.40.00.30.6-0.70.7-0.3-0.71.21.21.3-1.31.3-1.31.3-1.31.41.20.9-1.1-1.00.91.3-1.2-1.0
Locomotion distance, session 81.52.25.6-0.50.51.1-0.71.8-2.22.4-1.4-2.40.90.91.0-1.01.0-1.01.0-1.02.32.22.2-0.7-2.10.61.6-1.4-1.6
Degree of sensitization distance0.50.51.4-0.80.81.2-0.61.0-0.91.1-0.3-1.0-0.7-0.7-0.40.4-0.40.4-0.50.50.60.20.81.0-0.0-0.1-0.40.40.1
Degree of sensitization stereotypy0.20.30.80.8-0.8-0.70.6-0.50.7-0.90.70.90.40.40.2-0.20.2-0.20.4-0.4-0.5-0.4-0.6-0.10.20.5-0.1-0.10.1
Conditioned locomotion0.91.03.6-1.21.21.4-1.0-0.40.6-0.5-0.40.6-0.8-0.8-1.01.0-1.01.0-1.01.0-0.5-0.5-1.21.01.2-1.9-1.11.11.4
Cocaine response after cond. corrected3.03.46.52.6-2.5-2.32.4-1.50.6-0.71.80.62.32.32.3-2.32.3-2.32.4-2.40.10.10.0-1.9-2.11.81.2-1.1-1.3
Cocaine response after cond. not corrected3.43.88.72.9-2.9-3.02.9-2.41.4-1.62.61.52.02.02.0-2.02.0-2.02.1-2.1-0.9-0.9-0.7-1.7-1.61.60.6-0.6-0.8
Cocaine response before conditioning0.60.72.30.4-0.4-0.90.4-1.01.1-1.21.01.2-0.5-0.5-0.60.6-0.60.6-0.60.6-1.5-1.4-1.00.50.8-0.3-0.90.80.7
Saline control response3.54.610.60.3-0.3-1.11.3-3.03.2-2.91.93.0-1.2-1.2-1.41.4-1.41.4-1.51.5-3.2-3.2-2.90.92.3-1.9-2.62.82.6
Bone: connectivity density0.20.33.1-0.70.70.60.50.10.7-0.5-0.10.4-0.5-0.5-0.40.4-0.40.4-0.50.50.0-0.3-0.2-0.21.8-0.2-0.60.80.8
Bone: cortical apparent density0.10.10.20.4-0.4-0.30.20.2-0.20.10.3-0.10.30.30.4-0.40.4-0.40.5-0.5-0.00.00.2-0.0-0.10.40.2-0.3-0.4
Bone: cortical area0.10.10.3-0.00.00.0-0.20.2-0.50.6-0.2-0.60.30.30.4-0.40.4-0.40.4-0.40.30.30.5-0.1-0.40.00.3-0.2-0.4
Bone: cortical porosity0.30.32.00.9-0.9-0.30.30.8-0.50.2-0.2-0.20.20.20.2-0.20.2-0.20.2-0.20.60.30.70.5-0.61.40.3-0.9-0.6
Bone: cortical porosity0.20.21.30.5-0.6-0.1-0.00.9-0.60.4-0.5-0.4-0.0-0.00.0-0.00.0-0.00.0-0.00.80.40.80.4-0.51.10.4-0.8-0.5
Bone: cortical thickness0.20.30.60.4-0.4-0.2-0.10.5-0.80.7-0.2-0.70.40.40.4-0.40.4-0.40.4-0.40.50.30.80.1-0.80.60.4-0.5-0.7
Bone: cortical thickness0.30.30.90.0-0.0-0.1-0.1-0.50.5-0.50.20.6-0.6-0.6-0.50.5-0.50.5-0.60.6-1.0-0.8-0.80.80.5-0.5-0.80.60.7
Bone: cortical tissue density0.10.10.20.4-0.4-0.30.20.2-0.30.10.3-0.10.30.30.4-0.40.4-0.40.5-0.5-0.00.00.2-0.0-0.10.40.2-0.3-0.4
Condit. Reinf. active minus inactive responses1.92.26.01.3-1.3-1.41.7-2.22.0-2.01.92.1-0.4-0.4-0.40.4-0.40.4-0.50.5-2.5-2.4-2.11.00.7-0.2-1.81.51.4
Condit. Reinf. active-inactive response ratio2.32.56.62.0-2.0-1.92.0-2.62.1-2.32.32.30.20.20.2-0.20.2-0.20.1-0.1-2.4-2.3-2.20.70.30.1-1.41.21.0
Condit. Reinf. active responses1.11.33.40.3-0.3-0.50.5-1.31.4-1.31.01.4-0.9-0.9-0.90.9-0.90.9-1.01.0-1.8-1.8-1.51.20.9-0.8-1.71.41.4
Condit. Reinf. inactive responses0.50.52.0-1.41.41.1-1.10.7-0.30.5-0.7-0.5-0.7-0.7-0.70.7-0.70.7-0.70.70.40.30.30.10.7-1.0-0.20.30.4
Incentive salience index mean1.31.63.81.8-1.8-1.71.9-1.91.6-1.81.91.80.20.20.2-0.20.2-0.20.1-0.1-1.9-1.8-1.60.50.00.5-1.10.80.7
Condit. Reinf. lever presses0.71.03.61.9-1.9-1.41.4-0.90.5-0.91.00.91.01.00.9-0.90.9-0.90.8-0.8-0.3-0.3-0.3-0.4-1.11.20.3-0.7-0.5
Condit. Reinf. active minus inactive responses0.50.62.61.1-1.2-1.31.6-0.90.7-0.71.20.70.40.40.4-0.40.4-0.40.3-0.3-0.8-1.0-0.2-0.1-0.20.9-0.40.30.1
Condit. Reinf. active-inactive response ratio0.40.41.20.7-0.7-0.70.80.2-0.60.60.4-0.60.50.50.5-0.50.5-0.50.5-0.50.30.10.8-0.2-1.11.10.4-0.5-0.7
Condit. Reinf. active responses0.40.61.70.9-0.9-1.01.2-1.11.0-1.01.01.0-0.1-0.1-0.10.1-0.10.1-0.10.1-1.1-1.3-0.80.40.20.3-0.80.70.5
Condit. Reinf. inactive responses1.51.84.5-0.10.1-0.10.4-1.71.9-1.80.51.9-1.0-1.0-1.01.0-1.01.0-1.01.0-1.8-1.8-2.10.91.8-1.4-1.71.71.7
Condit. Reinf. lever presses0.20.30.60.6-0.6-0.70.8-0.70.2-0.20.30.20.60.60.7-0.70.7-0.70.6-0.6-0.00.00.0-0.8-0.50.30.4-0.3-0.4
Condit. Reinf. lever reinforcers received0.60.82.61.2-1.2-1.31.6-1.41.2-1.21.31.20.20.20.2-0.20.2-0.20.2-0.2-1.2-1.4-0.80.00.20.4-0.80.70.4
Conditioned reinforcement - actives3.53.57.9-2.12.11.7-1.71.1-0.80.9-1.1-0.8-2.7-2.7-2.82.8-2.82.8-2.62.6-0.2-0.00.12.10.4-1.6-1.41.31.0
Conditioned reinforcement - inactives0.10.10.5-0.20.2-0.00.50.30.10.20.7-0.2-0.1-0.1-0.00.0-0.00.00.0-0.0-0.0-0.30.3-0.20.70.3-0.30.70.1
Conditioned locomotion0.50.61.4-1.21.20.8-0.10.6-0.20.60.4-0.6-0.9-0.9-1.01.0-1.01.0-0.80.8-0.3-0.50.50.70.7-0.5-1.01.20.6
Patch foraging indifference point 0 sec0.20.30.8-0.60.60.7-0.30.2-0.10.2-0.1-0.1-0.6-0.6-0.70.7-0.70.7-0.60.6-0.4-0.3-0.20.90.8-0.4-0.80.80.6
Patch foraging indifference point AUC0.70.83.41.3-1.3-1.61.0-1.90.9-1.11.31.20.10.10.2-0.20.2-0.20.4-0.4-1.5-0.8-1.4-0.2-0.40.1-0.10.40.2
Delay disc. indifference point, 0s delay1.31.42.6-1.21.20.5-1.0-0.10.5-0.4-0.40.5-1.6-1.6-1.61.6-1.61.6-1.61.6-1.0-0.8-0.70.91.5-1.5-1.11.21.2
Delay disc. indifference point, 16s delay0.00.00.1-0.00.0-0.20.10.20.10.10.1-0.1-0.2-0.2-0.00.0-0.00.0-0.00.0-0.1-0.20.2-0.00.00.3-0.0-0.1-0.0
Delay disc. indifference point, 2s delay0.80.92.7-1.61.60.9-1.10.7-0.00.3-0.9-0.3-1.2-1.2-1.11.1-1.11.1-1.11.10.1-0.00.20.21.4-1.2-0.40.80.6
Delay disc. indifference point, 24s delay0.60.61.41.0-1.0-1.21.1-0.90.9-0.90.80.90.70.70.9-0.90.9-0.90.9-0.9-0.5-0.4-0.6-1.1-0.10.30.4-0.5-0.1
Delay disc. indifference point, 4s delay0.20.20.6-0.30.3-0.1-0.2-0.40.6-0.6-0.10.6-0.6-0.6-0.50.5-0.50.5-0.50.5-0.6-0.4-0.8-0.10.6-0.7-0.30.30.5
Delay disc. indifference point, 8s delay0.20.21.30.1-0.1-0.80.6-0.60.7-0.70.60.70.10.10.2-0.20.2-0.20.2-0.2-0.6-0.2-0.4-1.20.8-0.10.30.20.0
Indifference point function ln k1.11.55.3-1.31.31.6-1.22.3-1.61.8-1.7-1.80.60.60.3-0.30.3-0.30.3-0.32.11.71.9-0.40.00.20.9-1.0-0.9
Indifference point function log k1.11.55.3-1.31.31.6-1.22.3-1.61.8-1.7-1.80.60.60.3-0.30.3-0.30.3-0.32.11.71.9-0.40.00.20.9-1.0-0.9
Patch foraging total patch changes 0 sec0.20.30.7-0.70.70.8-0.50.4-0.40.5-0.4-0.5-0.5-0.5-0.60.6-0.60.6-0.50.5-0.10.00.10.80.5-0.4-0.50.60.3
Patch foraging total patch changes 12 sec0.30.31.10.8-0.8-0.60.8-1.00.3-0.41.00.4-0.1-0.10.1-0.10.1-0.10.2-0.2-0.9-0.8-0.60.7-0.30.2-0.70.80.2
Patch foraging total patch changes 18 sec0.81.03.20.7-0.7-0.80.8-1.71.2-1.30.91.4-0.7-0.7-0.50.5-0.50.5-0.30.3-1.8-1.3-1.80.70.3-0.5-1.11.20.9
Patch foraging total patch changes 24 sec1.21.43.2-0.50.40.1-0.5-0.80.4-0.50.10.7-1.8-1.8-1.61.6-1.61.6-1.61.6-1.5-1.0-1.21.60.5-1.0-1.41.41.2
Patch foraging total patch changes 6 sec0.40.71.3-1.01.01.2-0.70.5-0.80.7-0.8-0.7-1.1-1.1-1.01.0-1.01.0-0.90.9-0.00.30.01.10.3-0.6-0.60.80.5
Patch foraging time to switch 0 sec0.20.31.2-1.11.11.0-0.70.8-0.00.2-0.7-0.3-0.6-0.6-0.50.5-0.50.5-0.50.50.70.20.4-0.00.9-0.5-0.1-0.00.4
Patch foraging water rate 0 sec0.20.31.41.1-1.2-0.50.40.2-0.60.2-0.0-0.20.40.40.2-0.20.2-0.20.2-0.20.00.10.30.8-1.01.10.0-0.3-0.6
Patch foraging water rate 12 sec0.10.10.3-0.10.10.20.00.3-0.50.4-0.4-0.40.40.40.4-0.40.4-0.40.4-0.40.40.50.3-0.2-0.20.10.2-0.1-0.3
Patch foraging water rate 18 sec0.30.41.0-0.40.40.6-0.81.0-0.90.7-1.0-0.7-0.5-0.5-0.60.6-0.60.6-0.60.60.30.40.50.9-0.30.1-0.1-0.2-0.1
Patch foraging water rate 24 sec0.10.21.00.6-0.6-0.30.40.1-0.50.5-0.1-0.50.40.40.5-0.50.5-0.50.5-0.50.20.20.20.1-1.00.50.2-0.1-0.5
Patch foraging water rate 6 sec0.10.20.70.6-0.7-0.30.50.0-0.30.1-0.0-0.10.60.60.5-0.50.5-0.50.5-0.50.20.30.1-0.1-0.80.60.3-0.5-0.5
Seeking ratio, delayed vs. immediate footshock0.80.92.4-1.21.20.9-1.61.0-1.51.4-1.4-1.3-0.4-0.4-0.70.7-0.70.7-0.60.60.91.11.20.2-0.7-0.80.5-0.4-0.7
Distance traveled before self-admin1.41.53.01.4-1.4-1.61.7-1.01.1-0.81.60.71.71.71.5-1.51.5-1.51.5-1.5-0.2-1.00.2-1.30.41.10.2-0.1-0.3
Distance traveled after self-admin0.40.41.30.6-0.7-0.90.4-0.90.5-0.70.90.8-0.2-0.2-0.50.5-0.50.5-0.40.4-1.1-1.0-0.60.70.2-0.0-0.80.70.5
Extensor digitorum longus weight3.011.933.0-4.64.64.8-5.15.0-4.94.9-5.7-4.9-1.8-1.8-1.91.9-1.91.9-1.91.94.04.43.60.9-1.1-1.31.7-1.5-1.3
Bone: elastic displacement2.02.34.3-1.01.10.7-0.5-1.21.6-1.4-0.21.5-1.7-1.7-1.61.6-1.61.6-1.71.7-1.5-1.4-1.91.11.7-2.0-1.71.72.1
Bone: elastic work0.40.51.5-1.21.20.8-0.7-0.10.2-0.0-0.90.0-0.7-0.7-0.70.7-0.70.7-0.70.7-0.0-0.0-0.3-0.00.9-1.2-0.30.60.8
Bone: endosteal estimation0.10.20.7-0.80.80.7-0.50.3-0.00.1-0.5-0.1-0.5-0.5-0.50.5-0.50.5-0.50.50.20.20.00.10.8-0.6-0.20.40.4
Bone: endosteal perimeter0.20.41.4-0.40.40.00.2-1.11.0-0.80.60.8-0.2-0.2-0.10.1-0.10.1-0.20.2-0.7-0.7-1.0-0.40.9-1.2-0.51.00.9
Epididymis fat weight0.20.52.7-0.50.50.10.5-0.61.2-0.90.80.9-0.4-0.4-0.40.4-0.40.4-0.30.3-0.6-0.8-0.8-0.31.7-0.6-0.81.10.9
Delta time in closed arm before/after self-admin0.70.63.40.0-0.00.20.11.4-0.91.00.1-1.10.70.70.7-0.70.7-0.70.6-0.61.30.51.8-0.2-0.11.10.4-0.6-0.9
Delta time in open arm before/after self-admin0.40.40.80.4-0.4-0.4-0.3-0.30.1-0.20.10.10.80.80.8-0.80.8-0.80.9-0.9-0.00.6-0.6-0.8-0.40.00.9-0.7-0.5
Diff in mean of infusions in LGA sessions0.80.92.7-1.11.10.9-0.5-0.50.9-0.7-0.40.7-0.7-0.7-1.01.0-1.01.0-1.01.0-0.6-0.6-0.80.41.5-1.6-1.11.41.2
Delay discount exponential model param0.20.20.60.3-0.30.4-0.10.4-0.60.6-0.1-0.60.40.40.2-0.20.2-0.20.2-0.20.60.40.60.5-0.80.50.1-0.3-0.4
Extinction: sum of active levers before priming0.20.20.8-0.60.70.4-0.20.30.4-0.2-0.60.2-0.0-0.0-0.60.6-0.60.6-0.50.50.2-0.30.40.00.9-0.4-0.40.60.4
Active lever presses in extinction session 62.42.36.4-2.02.01.9-1.82.5-2.12.3-2.5-2.3-0.4-0.4-0.80.8-0.80.8-0.60.61.91.72.20.1-0.50.10.8-0.7-0.7
Bone: final force0.50.82.6-0.60.60.8-1.01.5-1.61.5-1.3-1.5-0.4-0.4-0.30.3-0.30.3-0.30.31.00.91.40.7-0.60.40.4-0.5-0.7
Bone: final moment0.50.82.3-0.80.81.0-1.11.5-1.51.4-1.3-1.4-0.6-0.6-0.60.6-0.60.6-0.60.60.90.71.20.9-0.30.20.1-0.2-0.4
Food consumed during 24 hour testing period0.20.20.9-0.20.2-0.30.1-0.90.4-0.40.00.4-0.6-0.6-0.50.5-0.50.5-0.40.4-0.9-0.4-0.8-0.1-0.1-0.7-0.20.50.4
Glucose1.11.64.6-1.91.92.1-1.70.9-1.01.1-1.7-1.0-1.2-1.2-1.41.4-1.41.4-1.31.30.50.60.11.30.2-1.6-0.70.70.7
Heart weight0.50.72.7-1.01.00.9-1.70.7-1.11.1-1.0-1.0-0.5-0.5-0.70.7-0.70.7-0.90.90.50.80.50.6-0.8-1.00.3-0.4-0.3
Delay discount hyperbolic model param0.20.20.70.5-0.50.20.20.2-0.50.40.1-0.40.60.60.4-0.40.4-0.40.4-0.40.50.30.50.4-0.90.60.1-0.3-0.4
Intermittent access intake day 1-15 change1.81.85.6-1.41.41.6-1.81.9-2.42.3-1.6-2.2-0.6-0.6-0.80.8-0.80.8-0.90.91.51.61.81.0-0.5-0.30.5-0.1-0.9
Intermittent access intake escalation1.61.54.3-1.31.21.4-1.71.6-2.11.9-1.5-1.8-0.8-0.8-1.11.1-1.11.1-1.21.21.11.31.41.1-0.2-0.40.20.1-0.7
Intermittent access intake escalation 22.52.48.4-1.31.31.4-1.82.4-2.92.7-2.1-2.70.20.2-0.10.1-0.10.1-0.10.12.02.42.30.0-0.90.41.4-0.9-1.6
Intermitt. access day 1 inactive lever presses1.51.63.01.5-1.5-1.41.6-0.70.4-0.61.40.41.51.51.7-1.71.7-1.71.7-1.7-0.20.0-0.2-1.4-0.41.40.8-0.5-0.9
Intermitt. access day 15 inactive lever presses0.30.31.21.1-1.1-0.80.9-0.70.2-0.30.70.30.40.40.6-0.60.6-0.60.5-0.5-0.1-0.2-0.1-0.2-0.70.90.1-0.1-0.2
Intermitt. access escalation Index0.20.20.50.1-0.00.0-0.1-0.50.5-0.7-0.30.70.30.30.1-0.10.1-0.10.4-0.40.20.3-0.7-0.60.6-0.40.5-0.40.2
Intermittent access day 1 total infusions0.50.61.7-1.21.20.8-0.40.40.10.20.3-0.2-1.3-1.3-0.90.9-0.90.9-0.80.8-0.3-0.40.00.60.8-0.8-1.01.10.8
Intermittent access day 15 total infusions3.43.86.9-2.52.42.2-2.21.6-1.41.5-1.2-1.4-2.6-2.6-2.62.6-2.62.6-2.52.50.30.50.72.10.9-1.7-1.21.40.8
Intermittent access terminal intake (last 3 days)3.43.76.9-2.62.62.5-2.52.1-2.02.1-1.6-2.0-2.3-2.3-2.32.3-2.32.3-2.12.11.01.11.31.80.3-1.4-0.61.00.3
Intermittent access total infusions2.22.55.1-2.12.11.8-1.50.9-0.50.9-0.3-0.8-2.3-2.3-2.12.1-2.12.1-1.91.9-0.1-0.10.21.61.0-1.7-1.31.61.1
Intermittent access day 1 locomotion1.01.02.7-1.61.61.3-1.21.1-1.01.2-0.6-1.1-1.3-1.3-1.11.1-1.11.1-0.90.90.40.60.70.50.1-0.8-0.30.50.3
Intermittent access day 15 total locomotion2.22.34.4-2.02.01.9-2.02.1-2.02.1-1.7-2.0-1.5-1.5-1.61.6-1.61.6-1.41.41.01.11.61.30.2-0.6-0.20.6-0.2
Intermittent access total locomotion2.02.34.2-2.12.01.8-1.81.6-1.61.7-1.2-1.6-1.9-1.9-1.81.8-1.81.8-1.71.70.40.61.21.60.3-1.0-0.80.90.3
Intermittent access standard deviation0.30.30.9-0.60.60.4-0.10.9-0.70.8-0.0-0.8-0.8-0.8-0.70.7-0.70.7-0.50.5-0.10.00.70.50.60.4-0.30.70.0
Left kidney weight1.43.97.32.7-2.7-2.72.4-1.60.7-0.81.90.72.52.52.4-2.42.4-2.42.4-2.4-0.1-0.1-0.2-2.2-2.01.91.6-1.5-1.6
Right kidney weight1.43.99.72.5-2.5-3.03.1-2.31.9-1.92.31.72.12.12.0-2.02.0-2.02.0-2.0-1.2-0.8-1.4-2.6-0.81.51.0-0.6-0.7
Cocaine induced anxiety0.10.10.40.6-0.6-0.4-0.0-0.50.0-0.40.30.4-0.2-0.20.0-0.00.0-0.00.1-0.1-0.20.1-0.50.1-0.40.30.2-0.3-0.0
Post-drug Anxiety1.71.95.12.3-2.3-2.01.9-1.41.2-1.31.81.31.31.31.4-1.41.4-1.41.5-1.5-0.6-0.9-0.5-0.9-0.61.50.3-0.5-0.3
Baseline Anxiety1.81.95.41.5-1.5-1.72.3-1.01.5-1.01.60.91.71.71.7-1.71.7-1.71.8-1.8-0.4-1.30.2-1.50.21.20.1-0.1-0.2
Tail length0.72.04.61.3-1.2-1.01.6-0.50.1-0.10.5-0.01.91.92.0-2.02.0-2.02.2-2.20.80.80.2-2.0-0.91.51.4-1.1-1.1
Length with tail0.20.82.70.4-0.4-0.41.4-0.30.5-0.30.50.11.11.11.3-1.31.3-1.31.4-1.40.40.3-0.3-1.60.30.90.7-0.4-0.3
Length without tail0.20.51.7-0.10.1-0.40.9-0.71.2-1.00.80.9-0.4-0.4-0.40.4-0.40.4-0.40.4-1.0-1.0-0.9-0.31.3-0.2-0.70.80.8
Times rat made contact with spout0.20.20.50.4-0.3-0.30.5-0.2-0.20.20.3-0.20.50.50.6-0.60.6-0.60.7-0.70.40.40.4-0.7-0.70.50.5-0.3-0.6
Lifetime Intake2.42.76.0-2.12.11.7-1.40.7-0.30.6-0.2-0.5-2.4-2.4-2.32.3-2.32.3-2.12.1-0.3-0.2-0.11.61.2-1.7-1.51.71.3
Liver weight, left0.30.51.40.5-0.5-0.51.1-0.91.0-0.91.20.80.60.60.7-0.70.7-0.70.6-0.6-0.5-0.5-0.7-0.80.6-0.1-0.30.50.3
Liver weight, right0.91.53.31.4-1.4-1.61.8-1.01.1-1.11.81.01.51.51.5-1.51.5-1.51.4-1.4-0.2-0.3-0.3-1.8-0.10.80.6-0.3-0.5
Locomotor activity0.60.92.71.2-1.2-0.91.6-1.31.0-1.01.21.01.11.10.9-0.90.9-0.90.9-0.9-0.7-0.6-1.0-0.7-0.30.7-0.00.00.1
Locomotor testing distance0.71.13.81.7-1.7-1.21.9-1.20.8-0.91.50.91.01.01.0-1.01.0-1.01.0-1.0-0.6-0.8-0.5-0.2-0.71.3-0.30.2-0.1
Locomotor testing rearing1.92.97.51.1-1.1-1.41.8-2.72.6-2.62.22.7-0.5-0.5-0.50.5-0.50.5-0.40.4-2.6-2.5-2.70.61.2-0.7-1.91.91.8
Locomotion in novel chamber0.40.51.60.4-0.3-0.50.2-0.30.2-0.2-0.30.11.31.30.8-0.80.8-0.80.8-0.80.20.4-0.3-1.2-0.70.20.9-0.8-0.6
Locomotion in novel chamber post-restriction1.61.94.11.5-1.5-1.31.2-0.0-0.20.20.2-0.21.91.91.6-1.61.6-1.61.7-1.70.70.70.6-1.5-1.62.01.6-1.6-1.4
Fecal boli incidents, locomotor time 10.50.51.20.5-0.5-0.50.7-0.70.6-0.51.00.41.01.01.1-1.11.1-1.11.1-1.1-0.10.0-0.2-1.10.2-0.20.4-0.1-0.2
Change in fecal boli incidents, locomotor task1.31.22.4-0.60.60.3-0.6-0.80.7-0.80.00.9-1.3-1.3-1.31.3-1.31.3-1.31.3-1.4-1.0-1.51.10.9-1.3-1.11.01.3
Time >=10cm from walls, locomotor time 12.02.04.91.9-1.9-2.22.0-2.21.8-2.01.92.00.90.91.0-1.01.0-1.00.9-0.9-1.8-1.5-1.7-0.90.30.4-0.10.10.2
Bouts of movement, locomotor time 10.60.71.4-0.90.91.0-0.80.5-0.30.3-0.8-0.3-1.1-1.1-1.01.0-1.01.0-1.11.1-0.0-0.20.01.20.7-0.7-0.80.80.8
Total resting periods, locomotor time 10.91.02.0-1.21.21.4-1.10.8-0.70.7-1.2-0.7-1.2-1.2-1.11.1-1.11.1-1.21.20.20.20.31.20.6-0.8-0.70.70.6
Rest time, locomotor task time 13.03.37.7-2.42.42.7-2.72.6-2.82.7-2.7-2.7-0.6-0.6-0.60.6-0.60.6-0.50.52.32.71.80.1-0.5-0.91.2-1.0-1.0
Distance moved, locomotor task time 12.52.77.42.3-2.3-2.32.6-2.22.4-2.32.52.30.50.50.4-0.40.4-0.40.3-0.3-2.2-2.7-1.50.30.51.2-1.41.00.9
Vertical activity count, locomotor time 11.21.34.41.3-1.3-1.41.5-1.41.8-1.81.41.8-0.1-0.1-0.20.2-0.20.2-0.30.3-1.6-2.1-1.10.60.70.2-1.30.81.0
Time >=10cm from walls, locomotor time 21.01.12.71.2-1.2-1.51.2-1.61.3-1.41.51.30.90.90.9-0.90.9-0.90.9-0.9-1.2-0.9-1.4-0.90.30.10.10.00.1
Bouts of movement, locomotor time 20.30.41.20.8-0.8-1.10.9-0.80.4-0.50.80.40.60.60.6-0.60.6-0.60.6-0.6-0.5-0.3-0.4-0.8-0.50.20.3-0.2-0.2
Total resting periods, locomotor time 20.40.51.50.9-0.9-1.21.0-0.90.5-0.50.90.50.70.70.7-0.70.7-0.70.7-0.7-0.5-0.3-0.4-0.9-0.50.30.4-0.3-0.3
Rest time, locomotor task time 20.50.52.0-1.01.00.8-1.00.8-0.90.9-1.4-0.9-0.3-0.3-0.40.4-0.40.4-0.40.40.81.10.8-0.3-0.3-0.60.7-0.6-0.4
Distance moved, locomotor task time 20.60.72.41.1-1.2-1.01.2-0.91.2-1.21.31.20.00.00.0-0.00.0-0.00.0-0.0-0.9-1.5-0.50.60.60.8-1.00.80.5
Vertical activity count, locomotor time 20.20.20.80.3-0.30.00.40.5-0.30.30.0-0.40.40.40.4-0.40.4-0.40.4-0.40.70.10.9-0.0-0.20.70.1-0.3-0.4
Light reinforcement 10.20.51.90.6-0.6-0.81.2-0.70.9-0.71.40.60.50.50.5-0.50.5-0.50.6-0.6-0.6-0.8-0.4-0.50.90.3-0.30.60.1
Light reinforcement 20.60.82.5-0.90.90.2-0.1-0.21.0-0.9-0.00.9-1.1-1.1-1.21.2-1.21.2-1.11.1-0.8-0.6-1.0-0.01.6-0.8-0.70.61.0
Bone: marrow area0.10.20.7-0.80.80.7-0.50.20.00.1-0.4-0.1-0.5-0.5-0.50.5-0.50.5-0.50.50.10.1-0.00.10.8-0.6-0.20.50.5
Bone: maximum diameter0.30.61.80.5-0.5-0.70.8-0.80.6-0.41.00.31.11.11.1-1.11.1-1.11.1-1.1-0.1-0.0-0.2-1.4-0.1-0.10.5-0.1-0.3
Bone: maximum force0.71.13.6-1.31.31.4-1.51.9-1.61.7-1.5-1.6-0.6-0.6-0.60.6-0.60.6-0.60.61.21.01.50.60.1-0.10.3-0.2-0.4
Bone: maximum moment0.71.13.3-1.41.41.5-1.51.8-1.51.5-1.5-1.5-0.8-0.8-0.80.8-0.80.8-0.80.81.00.81.20.80.4-0.3-0.00.0-0.1
Mean time between licks in bursts0.20.30.9-0.91.00.7-0.40.6-0.60.8-0.6-0.80.00.0-0.00.0-0.00.00.0-0.00.80.70.8-0.60.3-0.40.4-0.1-0.1
Mean num. licks in bursts0.10.20.50.0-0.0-0.20.00.4-0.50.60.0-0.5-0.4-0.4-0.40.4-0.40.4-0.40.4-0.0-0.20.70.5-0.40.6-0.10.1-0.4
Cd content in liver1.71.96.6-0.50.51.2-0.91.9-2.62.4-1.4-2.40.40.40.5-0.50.5-0.50.5-0.52.02.22.00.0-1.70.71.3-1.3-1.5
Co content in liver1.21.43.9-1.71.72.0-1.81.6-1.61.8-2.0-1.7-0.7-0.7-0.60.6-0.60.6-0.60.61.41.41.10.6-0.3-0.80.3-0.1-0.1
Cu content in liver0.70.91.9-1.21.21.0-0.60.9-0.20.3-1.0-0.3-1.4-1.4-1.21.2-1.21.2-1.21.2-0.1-0.20.20.91.3-0.4-0.80.80.7
Fe content in liver0.20.31.0-0.30.30.7-0.51.0-0.80.6-0.8-0.6-0.5-0.5-0.40.4-0.40.4-0.40.40.50.40.40.80.20.4-0.1-0.2-0.1
K content in liver2.22.16.01.5-1.5-1.91.9-0.51.0-1.01.50.81.81.81.8-1.81.8-1.81.8-1.80.20.00.3-2.40.01.61.2-1.0-1.0
Mg content in liver0.40.41.40.9-0.9-1.20.9-0.20.6-0.60.90.50.60.60.7-0.70.7-0.70.7-0.7-0.1-0.30.2-0.90.10.90.4-0.4-0.4
Mn content in liver0.00.10.40.1-0.1-0.10.60.10.2-0.00.5-0.00.10.10.2-0.20.2-0.20.2-0.2-0.0-0.20.1-0.20.30.4-0.20.30.1
Na content in liver1.01.13.01.3-1.3-1.41.5-1.11.6-1.71.51.70.50.50.6-0.60.6-0.60.6-0.6-1.2-1.2-1.2-0.50.90.5-0.40.20.3
Rb content in liver0.30.41.60.3-0.4-0.51.1-0.30.9-0.80.90.7-0.0-0.0-0.10.1-0.10.1-0.20.2-0.9-1.1-0.50.21.30.3-0.80.80.6
Se content in liver0.60.73.0-0.50.50.7-0.71.7-1.41.4-1.0-1.4-0.2-0.2-0.20.2-0.20.2-0.20.21.00.91.30.4-0.30.80.5-0.7-0.8
Sr content in liver0.30.30.90.2-0.2-0.60.5-0.90.9-0.80.70.80.40.40.4-0.40.4-0.40.4-0.4-0.4-0.3-0.6-0.90.4-0.50.10.20.2
Zn content in liver1.61.83.00.8-0.8-0.80.90.4-0.81.00.4-1.11.71.71.7-1.71.7-1.71.7-1.71.31.01.6-1.7-1.01.41.6-1.2-1.6
Bone: minimum diameter0.50.92.6-1.31.31.3-1.61.4-1.51.6-1.4-1.6-0.4-0.4-0.40.4-0.40.4-0.50.51.00.91.20.5-0.0-0.50.3-0.1-0.4
Time in familiar zone, hab. session 10.10.10.90.5-0.5-0.10.3-0.1-0.50.40.1-0.30.10.10.1-0.10.1-0.10.2-0.20.1-0.00.20.6-1.00.5-0.10.0-0.1
Time in novel zone, hab. session 10.00.00.2-0.00.0-0.3-0.10.10.2-0.20.20.20.00.00.1-0.10.1-0.10.0-0.0-0.2-0.1-0.1-0.40.4-0.10.2-0.2-0.1
Total zone transitions, hab. session 10.40.63.70.7-0.6-0.80.9-1.91.2-1.10.81.10.00.00.0-0.00.0-0.0-0.10.1-1.1-0.9-1.3-0.2-0.4-0.6-0.40.70.7
Total locomotion distance, hab. session 10.20.31.10.0-0.0-0.20.0-1.00.7-0.70.10.8-0.5-0.5-0.50.5-0.50.5-0.50.5-0.7-0.5-1.00.2-0.1-0.7-0.40.40.6
Locomotion velocity, hab. session 10.10.21.20.3-0.3-0.40.2-1.10.8-0.80.30.8-0.0-0.0-0.10.1-0.10.1-0.10.1-0.6-0.4-0.9-0.2-0.3-0.5-0.10.10.4
Time in familiar zone, hab. session 20.10.10.30.1-0.10.10.10.2-0.20.20.1-0.20.40.40.5-0.50.5-0.50.6-0.60.30.20.2-0.2-0.00.20.3-0.3-0.3
Time in novel zone, hab. session 20.10.10.30.3-0.3-0.30.10.0-0.1-0.0-0.00.0-0.3-0.3-0.30.3-0.30.3-0.40.4-0.3-0.30.10.6-0.30.4-0.30.1-0.0
Total zone transitions, hab. session 20.71.03.80.8-0.7-1.31.6-1.31.1-0.71.10.61.11.11.1-1.11.1-1.11.1-1.1-0.2-0.3-0.2-1.9-0.40.30.6-0.1-0.3
Total locomotion distance, hab. session 20.81.12.91.1-1.0-1.51.7-1.41.3-1.11.41.01.01.01.0-1.01.0-1.01.1-1.1-0.4-0.6-0.4-1.7-0.10.40.4-0.1-0.1
Locomotion velocity, hab. session 20.70.92.90.9-0.9-1.41.6-1.41.4-1.11.41.10.90.90.9-0.90.9-0.90.9-0.9-0.4-0.6-0.4-1.7-0.00.20.40.0-0.0
Novel to familiar place preference ratio0.00.00.10.2-0.20.0-0.20.0-0.20.0-0.00.0-0.0-0.00.0-0.00.0-0.0-0.00.00.00.1-0.10.4-0.30.0-0.00.1-0.1
Novelty place preference0.10.10.50.3-0.30.0-0.30.4-0.60.4-0.3-0.40.20.20.2-0.20.2-0.20.2-0.20.40.50.40.3-0.70.40.3-0.3-0.5
Time in novel zone, NPP test0.10.10.50.1-0.10.2-0.50.5-0.70.5-0.3-0.5-0.1-0.1-0.00.0-0.00.0-0.00.00.30.30.40.6-0.60.20.1-0.1-0.3
Total zone transitions, NPP test0.81.11.91.1-1.1-1.11.2-0.2-0.20.40.7-0.41.21.21.3-1.31.3-1.31.3-1.30.40.20.8-1.2-1.31.41.0-0.8-1.0
Total locomotion distance, NPP test0.20.30.50.2-0.2-0.20.50.2-0.30.4-0.1-0.50.50.50.5-0.50.5-0.50.6-0.60.50.40.7-0.7-0.60.70.6-0.6-0.6
Locomotion velocity, NPP test0.40.61.50.5-0.5-0.60.80.1-0.10.30.2-0.31.01.00.9-0.90.9-0.91.0-1.00.60.40.8-1.2-0.71.00.9-0.8-0.8
Intraocular pressure0.10.10.3-0.40.40.3-0.1-0.3-0.30.4-0.4-0.4-0.1-0.1-0.10.1-0.10.1-0.10.1-0.20.1-0.20.0-0.5-0.4-0.00.40.2
Delta distance traveled before/after self-admin3.33.68.0-1.31.21.2-1.7-0.1-0.1-0.4-0.60.6-2.7-2.7-2.72.7-2.72.7-2.62.6-1.4-0.7-1.42.81.0-2.2-2.01.71.7
Delta ambulatory time before/after self-admin2.32.65.6-1.21.11.2-1.50.0-0.2-0.2-0.60.3-2.3-2.3-2.32.3-2.32.3-2.22.2-1.0-0.4-1.12.40.7-1.9-1.61.41.4
Parametrial fat weight0.51.02.4-1.31.30.8-0.4-0.20.4-0.1-0.30.1-1.1-1.1-1.21.2-1.21.2-1.11.1-0.7-0.7-0.60.61.5-1.3-1.11.61.1
Pavlov. Cond. lever latency0.60.71.70.1-0.1-0.0-0.20.9-0.80.8-0.1-0.90.80.81.0-1.01.0-1.01.3-1.31.00.91.0-0.9-0.20.71.1-1.0-1.0
Pavlov. Cond. magazine entry latency0.50.62.11.4-1.4-0.81.4-0.70.5-0.60.90.60.80.80.8-0.80.8-0.80.7-0.70.0-0.2-0.3-0.2-0.91.00.1-0.2-0.3
Pavlov. Cond. change in total contacts0.30.30.80.4-0.4-0.10.4-0.50.7-0.90.30.9-0.4-0.4-0.50.5-0.50.5-0.60.6-0.6-0.5-0.90.50.1-0.0-0.60.40.5
Pavlov. Cond. index score0.20.20.60.5-0.5-0.20.7-0.80.6-0.70.40.8-0.1-0.1-0.30.3-0.30.3-0.40.4-0.5-0.6-0.70.5-0.3-0.1-0.60.50.4
Pavlov. Cond. latency score0.20.20.70.6-0.7-0.40.8-0.80.6-0.60.40.60.10.1-0.10.1-0.10.1-0.30.3-0.4-0.5-0.60.4-0.50.0-0.50.40.2
Pavlov. Cond. lever contacts0.30.40.7-0.00.00.10.1-0.70.5-0.50.20.6-0.6-0.6-0.70.7-0.70.7-0.90.9-0.7-0.7-0.70.8-0.2-0.6-0.90.80.7
Pavlov. Cond. magazine entry number0.40.51.9-1.31.40.7-1.30.8-0.70.9-0.9-0.9-0.5-0.5-0.40.4-0.40.4-0.30.30.30.50.6-0.20.5-0.80.30.0-0.0
Pavlov. Cond. intertrial magazine entries0.91.12.0-1.31.30.7-0.70.10.3-0.1-0.40.2-1.3-1.3-1.41.4-1.41.4-1.41.4-0.7-0.7-0.40.81.2-1.1-1.11.21.1
Pavlov. Cond. lever-magazine prob. diff.0.20.20.60.5-0.5-0.20.8-0.80.7-0.70.40.8-0.1-0.1-0.20.2-0.20.2-0.30.3-0.4-0.5-0.70.4-0.3-0.0-0.60.50.4
Pavlov. Cond. response bias0.30.31.31.0-1.0-0.61.1-0.80.8-0.90.70.90.20.20.2-0.20.2-0.20.1-0.1-0.4-0.5-0.60.2-0.30.5-0.40.20.2
Pavlov. Cond. lever latency0.10.10.4-0.20.10.2-0.30.6-0.20.1-0.2-0.1-0.3-0.3-0.30.3-0.30.3-0.30.3-0.10.1-0.00.40.30.2-0.1-0.20.1
Pavlov. Cond. magazine entry latency0.40.51.50.7-0.7-0.80.6-0.4-0.30.20.0-0.31.01.00.7-0.70.7-0.70.7-0.70.30.40.5-1.0-1.20.70.9-0.8-0.9
Pavlov. Cond. change in total contacts1.01.42.51.6-1.6-1.41.5-0.90.1-0.20.90.11.41.41.5-1.51.5-1.51.5-1.50.40.20.4-1.1-1.61.30.9-0.7-1.1
Pavlov. Cond. index score0.30.31.30.8-0.8-0.70.7-0.6-0.10.10.2-0.10.70.70.6-0.60.6-0.60.6-0.60.20.10.4-0.6-1.20.60.5-0.4-0.6
Pavlov. Cond. latency score0.50.72.20.8-0.8-0.80.6-0.4-0.40.40.1-0.41.01.00.9-0.90.9-0.90.9-0.90.60.50.7-0.9-1.50.81.0-0.8-1.0
Pavlov. Cond. lever contacts0.20.30.90.5-0.5-0.20.4-0.3-0.30.30.1-0.30.80.80.8-0.80.8-0.80.7-0.70.60.40.5-0.5-0.90.40.5-0.3-0.6
Pavlov. Cond. magazine entry number0.91.12.4-1.31.31.4-1.40.50.2-0.2-0.60.2-1.2-1.2-1.11.1-1.11.1-1.11.1-0.4-0.2-0.81.11.4-1.5-1.00.91.1
Pavlov. Cond. intertrial magazine entries0.50.73.4-0.30.3-0.1-0.1-0.21.0-0.80.60.8-0.7-0.7-0.70.7-0.70.7-0.70.7-1.1-1.2-0.80.61.9-0.7-1.11.01.0
Pavlov. Cond. lever-magazine prob. diff.0.30.41.60.8-0.8-0.80.7-0.6-0.20.10.2-0.10.70.70.6-0.60.6-0.60.6-0.60.30.20.4-0.6-1.30.70.6-0.4-0.7
Pavlov. Cond. response bias0.20.30.90.5-0.4-0.20.5-0.2-0.30.3-0.0-0.30.70.70.6-0.60.6-0.60.6-0.60.60.40.6-0.4-0.90.50.5-0.3-0.6
Time in closed arm before self-admin0.10.10.50.0-0.0-0.1-0.2-0.10.1-0.1-0.60.2-0.7-0.7-0.50.5-0.50.5-0.50.5-0.30.2-0.30.0-0.20.10.2-0.10.1
Time in closed arm after self-admin0.70.72.90.0-0.10.4-0.41.4-1.11.2-0.5-1.20.20.20.4-0.40.4-0.40.4-0.41.41.01.7-0.0-0.91.00.8-0.8-1.0
Time in open arm before self-admin0.10.20.5-0.30.30.60.30.6-0.40.60.2-0.60.50.50.4-0.40.4-0.40.2-0.20.60.10.70.00.40.2-0.20.2-0.1
Time in open arm after self-admin0.10.20.6-0.40.50.3-0.1-0.30.3-0.10.30.10.60.60.4-0.40.4-0.40.5-0.50.00.1-0.4-0.80.6-0.60.20.10.1
Bone: periosteal estimation0.00.10.3-0.50.60.5-0.40.3-0.20.3-0.4-0.3-0.1-0.1-0.00.0-0.00.0-0.10.10.30.20.3-0.10.4-0.40.10.20.1
Bone: periosteal perimeter0.20.41.40.3-0.2-0.70.5-1.21.0-0.80.90.80.30.30.3-0.30.3-0.30.3-0.3-0.8-0.8-0.8-0.50.4-0.6-0.30.70.4
Bone: post-yield work0.20.20.4-0.10.10.20.10.4-0.50.60.1-0.60.60.60.6-0.60.6-0.60.6-0.60.60.50.7-0.6-0.10.20.5-0.2-0.6
Progressive ratio test 1 active lever presses0.90.92.1-0.90.90.6-0.1-0.20.7-0.40.40.4-1.3-1.3-1.21.2-1.21.2-1.11.1-0.7-0.8-0.50.71.0-1.0-1.31.41.1
Progressive ratio test 1 breakpoint0.70.71.5-1.11.10.7-0.30.10.3-0.00.20.0-1.2-1.2-1.11.1-1.11.1-1.01.0-0.3-0.4-0.20.60.8-0.9-1.01.20.8
Progressive ratio test 1 inactive lever presses0.20.20.80.4-0.4-0.40.80.10.1-0.10.60.00.30.30.5-0.50.5-0.50.6-0.60.10.10.2-0.7-0.00.90.3-0.1-0.3
Progressive ratio test 2 active lever presses2.62.86.2-2.02.01.7-1.70.8-0.60.7-0.6-0.5-2.3-2.3-2.52.5-2.52.5-2.32.3-0.20.10.11.80.8-1.7-1.31.41.0
Progressive ratio test 2 breakpoint2.22.55.5-2.01.91.6-1.70.7-0.60.6-0.7-0.5-2.2-2.2-2.32.3-2.32.3-2.12.1-0.20.10.11.60.8-1.6-1.11.40.9
Progressive ratio test 2 inactive lever presses0.30.40.9-0.70.70.4-0.20.3-0.20.30.2-0.3-0.9-0.9-0.90.9-0.90.9-0.90.9-0.2-0.00.10.50.3-0.1-0.50.80.3
Incentive Sensitization - Responses1.41.53.0-1.61.51.3-1.60.7-0.90.8-0.6-0.7-1.5-1.5-1.71.7-1.71.7-1.71.70.10.50.31.20.2-1.2-0.60.90.4
Incentive Sensitization - Breakpoint1.51.63.0-1.61.61.4-1.70.8-1.11.0-0.7-0.9-1.5-1.5-1.71.7-1.71.7-1.61.60.20.70.41.20.1-1.2-0.50.70.3
Sum of active levers in priming session hrs 5-60.50.51.4-1.21.21.0-0.80.8-0.40.7-0.9-0.7-0.4-0.4-0.60.6-0.60.6-0.60.60.40.10.70.40.4-0.8-0.40.50.3
Progressive ratio0.40.51.7-1.21.20.7-0.90.5-0.70.8-0.8-0.80.20.20.2-0.20.2-0.20.3-0.30.71.30.4-1.20.1-1.00.9-0.2-0.5
Food seeking constrained by brief footshock2.83.49.3-3.03.12.5-2.11.2-0.70.9-1.9-0.8-2.4-2.4-2.22.2-2.22.2-2.12.10.40.6-0.01.01.7-2.2-0.91.21.2
Seeking ratio, punishment vs. effort0.60.72.4-0.40.30.5-0.30.3-0.1-0.0-0.40.1-1.3-1.3-1.21.2-1.21.2-1.31.3-0.3-0.7-0.11.60.40.0-1.10.50.8
Retroperitoneal fat weight0.41.33.7-0.30.3-0.20.3-0.61.5-1.30.61.3-1.0-1.0-1.31.3-1.31.3-1.41.4-1.3-1.5-1.20.61.9-0.6-1.31.11.3
Reaction time number correct0.40.61.6-1.31.31.2-1.00.9-0.40.4-1.0-0.4-1.0-1.0-0.90.9-0.90.9-0.80.80.10.20.10.60.8-1.0-0.40.40.5
Reaction time mean minus median0.40.51.30.5-0.5-0.50.2-0.60.5-0.70.20.8-0.9-0.9-0.90.9-0.90.9-0.80.8-0.8-1.0-0.81.20.3-0.1-0.90.50.7
Reaction time mean minus median AUC0.40.51.90.5-0.5-0.30.2-0.30.3-0.50.30.6-1.0-1.0-0.90.9-0.90.9-0.70.7-0.6-1.0-0.51.40.40.1-1.00.50.7
Reaction time num false alarms2.02.85.80.0-0.00.6-0.81.8-2.42.2-1.5-2.31.51.51.2-1.21.2-1.21.2-1.22.32.42.2-0.9-2.31.32.1-2.0-2.2
Reaction time num false alarms AUC1.92.64.80.3-0.30.3-0.31.5-2.12.0-1.2-2.01.71.71.4-1.41.4-1.41.4-1.42.22.22.0-1.0-2.21.42.0-2.0-2.2
Reaction time trials correct on left0.40.61.6-1.31.31.2-1.00.9-0.40.4-1.0-0.4-1.0-1.0-0.90.9-0.90.9-0.80.80.10.20.10.60.8-1.0-0.40.40.5
Reaction time trials on left0.40.51.3-1.11.11.1-0.90.8-0.30.4-0.9-0.4-0.9-0.9-0.80.8-0.80.8-0.70.70.10.20.00.60.8-0.9-0.40.40.5
Reaction time mean1.11.54.00.6-0.7-1.10.6-1.41.4-1.51.31.6-1.1-1.1-1.11.1-1.11.1-1.01.0-1.9-2.0-1.41.20.9-0.4-1.51.31.2
Reaction time mean AUC1.01.43.70.6-0.6-0.90.6-1.21.3-1.41.11.4-1.1-1.1-1.21.2-1.21.2-1.11.1-1.7-1.9-1.21.31.0-0.3-1.51.21.2
Median of all reaction times1.21.74.20.4-0.4-0.90.4-1.41.5-1.51.21.6-1.2-1.2-1.31.3-1.31.3-1.21.2-2.0-2.0-1.51.21.1-0.6-1.61.41.3
Reaction time omissions1.01.33.61.9-1.9-1.61.4-0.60.2-0.40.90.31.31.31.3-1.31.3-1.31.4-1.40.1-0.20.2-0.8-1.31.50.8-1.0-1.0
Reaction time false alarm rate2.02.75.71.2-1.2-0.60.30.8-1.51.4-0.2-1.42.12.11.8-1.81.8-1.81.8-1.81.71.71.7-1.2-2.41.92.0-2.0-2.2
Reaction time premature initiation rate0.40.62.11.0-1.0-1.40.7-0.90.1-0.21.20.20.60.60.9-0.90.9-0.90.9-0.9-0.6-0.30.0-0.7-0.90.60.4-0.2-0.6
Reaction time premature initiations0.20.31.00.6-0.6-1.00.4-0.70.2-0.30.90.30.20.20.6-0.60.6-0.60.6-0.6-0.7-0.4-0.2-0.5-0.40.10.10.0-0.2
Std. dev. reaction times0.40.52.41.5-1.5-1.41.0-0.70.4-0.70.80.7-0.1-0.1-0.10.1-0.10.10.0-0.0-0.8-0.9-0.40.6-0.51.1-0.3-0.1-0.1
Reaction time trials completed0.40.51.3-1.11.11.1-0.90.8-0.30.4-0.9-0.4-0.9-0.9-0.80.8-0.80.8-0.70.70.10.20.00.60.8-0.9-0.40.40.5
Reaction time trials AUC0.40.51.3-1.21.21.1-0.90.9-0.50.5-1.0-0.5-0.9-0.9-0.80.8-0.80.8-0.70.70.20.20.20.60.7-0.8-0.30.30.4
Run reversals in cocaine runway, females1.31.22.51.3-1.2-1.41.6-1.41.4-1.31.11.20.90.91.3-1.31.3-1.31.2-1.2-0.7-0.5-1.2-1.60.00.40.6-0.4-0.0
Run reversals in cocaine runway, males1.21.22.50.9-0.9-0.91.00.4-0.60.50.2-0.61.31.31.2-1.21.2-1.21.2-1.21.20.81.4-1.4-1.01.61.3-1.2-1.3
Latency to leave start box in cocaine runway1.71.94.71.8-1.8-2.11.7-2.12.0-2.02.22.00.70.70.8-0.80.8-0.80.8-0.8-1.7-1.6-1.6-0.60.40.4-0.50.40.6
Latency to leave start box in cocaine runway, F0.90.92.81.5-1.5-1.71.2-1.41.0-1.01.51.00.50.50.8-0.80.8-0.80.9-0.9-1.1-1.1-0.8-0.2-0.60.4-0.20.00.3
Latency to leave start box in cocaine runway, M1.91.95.90.3-0.3-0.80.8-1.92.4-2.41.42.4-0.2-0.2-0.60.6-0.60.6-0.60.6-1.9-1.7-2.2-0.22.1-1.1-1.11.31.5
Std. dev. time between licks in bursts1.31.63.10.7-0.7-0.40.70.7-1.31.30.0-1.41.61.61.3-1.31.3-1.31.3-1.31.51.21.8-1.1-1.61.41.4-1.2-1.6
Total sessions with >9 infusions2.22.45.7-0.60.6-0.20.8-1.52.0-1.61.81.6-1.5-1.5-1.41.4-1.41.4-1.41.4-1.9-1.9-1.80.41.9-1.5-1.92.42.1
Short access day 1 total inactive lever presses0.91.03.20.3-0.3-0.91.1-1.51.8-1.61.61.5-0.2-0.2-0.30.3-0.30.3-0.40.4-1.4-1.4-1.3-0.51.1-0.5-0.70.80.9
Short access day 10 total inactive lever presses3.33.68.12.1-2.0-1.62.0-0.1-0.0-0.01.4-0.12.52.52.8-2.82.8-2.82.8-2.80.60.40.6-2.0-0.82.61.4-1.1-1.5
Short access day 1 total infusions1.01.11.9-1.11.20.5-0.1-0.20.8-0.60.40.6-1.4-1.4-1.41.4-1.41.4-1.41.4-0.9-0.7-0.70.31.2-0.9-1.11.31.2
Short access day 10 total infusions1.01.12.5-1.61.61.1-1.00.9-0.50.8-0.3-0.8-1.6-1.6-1.41.4-1.41.4-1.21.2-0.00.10.40.80.5-0.9-0.71.10.5
Short access total infusions1.71.94.2-1.51.50.8-0.4-0.10.7-0.30.50.4-2.0-2.0-1.81.8-1.81.8-1.71.7-1.0-0.9-0.70.91.4-1.5-1.51.71.5
Short access day 1 locomotion1.61.84.8-2.22.21.9-1.21.7-1.21.4-0.9-1.3-1.4-1.4-1.51.5-1.51.5-1.51.50.70.71.00.70.8-0.8-0.60.70.4
Short access day 10 total locomotion0.10.10.3-0.00.0-0.30.20.2-0.50.60.1-0.60.10.10.2-0.20.2-0.20.3-0.30.00.10.5-0.4-0.30.30.30.2-0.4
Short access total locomotion1.21.32.9-1.11.10.4-0.4-0.10.3-0.10.50.2-1.7-1.7-1.61.6-1.61.6-1.51.5-1.0-0.8-0.51.01.0-1.2-1.31.41.1
One hour access (0.3 mA shock)4.85.613.1-2.32.32.0-2.21.2-0.90.7-1.0-0.6-3.6-3.6-3.53.5-3.53.5-3.33.3-0.3-0.20.23.11.4-1.8-2.01.91.4
Compulsive drug intake0.70.72.61.0-1.1-0.8-0.3-0.80.1-0.90.31.0-1.0-1.0-1.01.0-1.01.0-0.90.9-1.2-0.5-1.01.6-0.10.0-0.70.20.3
One hour access (shock baseline)3.43.98.6-2.92.92.7-2.01.7-0.91.3-1.1-1.3-2.4-2.4-2.52.5-2.52.5-2.42.40.70.30.81.81.3-1.9-1.41.71.1
Social response proportion1.71.85.91.0-1.0-1.71.4-2.42.4-2.12.12.10.40.40.5-0.50.5-0.50.4-0.4-1.8-1.9-1.8-0.80.8-0.8-0.70.80.9
Social responses1.41.94.42.1-2.1-1.91.7-1.20.6-0.71.50.71.61.61.7-1.71.7-1.71.6-1.6-0.2-0.5-0.2-1.0-1.41.30.6-0.7-0.8
Social time0.40.51.50.6-0.6-1.20.7-0.70.2-0.10.60.10.70.70.9-0.90.9-0.90.7-0.7-0.3-0.10.2-1.2-0.60.40.7-0.5-0.5
Soleus weight0.61.84.9-1.71.61.9-2.01.8-1.71.6-2.2-1.5-1.0-1.0-1.31.3-1.31.3-1.41.40.91.20.81.20.1-0.70.1-0.0-0.1
Bone: stiffness0.50.83.3-0.90.91.1-0.81.8-1.51.5-1.1-1.60.00.00.1-0.10.1-0.10.1-0.11.41.21.5-0.1-0.00.40.6-0.5-0.7
Tibialis anterior weight1.24.18.6-2.52.51.6-1.7-0.30.9-0.7-1.20.7-2.5-2.5-2.62.6-2.62.6-2.62.6-1.4-0.9-1.51.22.4-2.9-1.72.02.2
Time to tail flick, vehicle, before self-admin1.21.23.31.1-1.1-1.81.7-1.71.8-1.61.51.60.30.30.5-0.50.5-0.50.5-0.5-1.6-1.5-1.3-1.00.70.3-0.20.20.6
Time to tail flick, vehicle, after self-admin1.41.52.80.4-0.4-0.10.20.8-1.21.2-0.9-1.21.01.01.3-1.31.3-1.31.5-1.51.61.61.3-1.3-1.61.21.7-1.5-1.3
Time to tail flick, test, before self-admin0.00.00.20.0-0.10.10.10.2-0.00.10.5-0.1-0.2-0.2-0.10.1-0.10.1-0.00.00.3-0.00.50.3-0.00.2-0.20.10.0
Time to tail flick, test, after self-admin0.40.41.00.7-0.7-0.70.7-0.41.0-0.91.00.80.80.80.5-0.50.5-0.50.6-0.6-0.1-0.1-0.3-0.90.50.70.3-0.3-0.2
Delta time to tail flick, vehicle, before/after SA0.70.71.70.5-0.50.10.00.6-0.90.8-0.5-0.80.70.70.9-0.90.9-0.90.9-0.91.11.01.0-0.3-1.30.90.9-0.8-0.9
Delta time to tail flick, test, before/after SA1.00.93.00.7-0.7-1.01.1-1.21.7-1.71.11.60.40.40.2-0.20.2-0.20.1-0.1-1.3-0.9-1.5-0.81.20.1-0.20.30.5
Tibia length0.20.72.50.9-0.8-1.21.6-1.21.2-1.01.51.00.30.30.4-0.40.4-0.40.4-0.4-1.1-1.1-0.6-0.60.10.4-0.40.50.4
Ambulatory time before self-admin1.21.33.01.2-1.2-1.31.4-0.60.7-0.41.50.31.71.71.5-1.51.5-1.51.4-1.40.0-0.50.4-1.3-0.11.20.5-0.4-0.6
Ambulatory time after self-admin0.10.20.50.0-0.0-0.3-0.3-0.1-0.1-0.10.20.1-0.4-0.4-0.60.6-0.60.6-0.50.5-0.5-0.40.00.70.3-0.2-0.50.50.2
Bone: tissue strength0.40.42.4-0.10.1-0.20.8-0.61.2-1.00.90.90.10.10.0-0.00.0-0.00.1-0.1-0.5-0.8-0.7-0.51.5-0.4-0.60.90.7
Total heroin consumption0.40.42.0-1.31.40.5-0.50.40.3-0.1-0.6-0.0-0.4-0.4-0.60.6-0.60.6-0.70.7-0.20.10.1-0.71.4-0.7-0.10.40.4
Bone: trabecular number1.01.66.3-0.60.60.30.7-1.01.8-1.60.61.5-1.1-1.1-1.01.0-1.01.0-1.01.0-1.1-1.6-1.30.42.5-1.0-1.61.71.9
Bone: trabecular spacing0.20.20.90.0-0.10.1-0.70.4-0.90.7-0.5-0.70.30.30.2-0.20.2-0.20.2-0.20.30.60.30.2-1.00.10.5-0.7-0.7
Bone: trabecular thickness1.31.54.6-1.31.31.1-0.2-0.31.1-0.8-0.30.8-1.5-1.5-1.41.4-1.41.4-1.41.4-0.7-0.9-1.00.72.1-1.3-1.41.61.7
Bone: trabecular tissue density1.52.27.10.5-0.5-1.20.9-2.12.1-1.92.12.0-0.7-0.7-0.70.7-0.70.7-0.60.6-2.7-2.4-2.00.61.3-1.2-1.71.81.6
Water consumed over 24 hours0.10.10.4-0.10.1-0.00.10.3-0.30.3-0.2-0.30.20.20.3-0.30.3-0.30.3-0.30.30.50.3-0.7-0.20.30.6-0.5-0.5
Number of responses in last shaping day2.82.96.5-2.52.52.5-1.92.4-1.72.1-1.9-2.0-1.7-1.7-1.71.7-1.71.7-1.61.61.51.01.71.2-0.1-0.9-0.50.40.1