Hub : Genes

Hpse

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 OFC gene expression Hpse 0.19 0.11 2.2e-03 0.08 0.08 0.04 0.09 5.5e-03 5.0e-03 3.3e-02 4.5e-03
2 BLA gene expression Hpse 0.25 0.11 2.1e-08 0.07 0.14 0.12 0.12 1.4e-04 8.5e-08 5.1e-07 4.6e-07
3 pVTA gene expression Hpse 0.11 0.06 3.2e-04 0.01 0.04 0.02 0.02 4.9e-02 5.7e-04 9.0e-03 6.2e-03
4 Eye gene expression Hpse 0.4 0.16 1.0e-03 0.2 0.11 0.04 0.14 6.1e-04 8.4e-03 7.4e-02 3.3e-03
5 PL gene expression Hpse 0.04 0.03 6.7e-04 0 0.02 0.01 0.01 1.7e-01 3.1e-03 1.5e-02 2.8e-02
6 Liver gene expression Hpse 0.18 0.07 1.1e-14 0.11 0.11 0.1 0.11 3.0e-12 3.4e-12 1.7e-11 4.3e-12
7 Brain gene expression Hpse 0.05 0.03 9.2e-04 0.01 0.03 0.02 0.02 1.8e-02 4.2e-04 3.1e-03 2.9e-03
8 Liver mRNA stability Hpse 0.05 0.03 2.2e-04 0.01 0.03 0.02 0.01 5.3e-02 4.4e-04 6.1e-03 7.0e-03
9 Adipose mRNA stability Hpse 0.19 0.09 0.0e+00 0.13 0.13 0.18 0.13 1.9e-14 4.2e-14 1.7e-19 3.9e-14
10 Adipose gene expression Hpse 0.31 0.13 0.0e+00 0.18 0.23 0.23 0.23 1.2e-19 7.0e-25 1.0e-25 1.7e-25

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10
Bone: apparent density2.13.98.42.02.91.9-2.01.42.2-0.4-2.62.1-1.0
Area under the delay curve0.81.33.80.5-0.20.5-0.70.5-2.01.91.11.4-1.0
BMI with tail0.41.52.91.71.31.3-1.30.9-0.61.3-0.21.3-1.4
BMI without tail0.42.34.62.12.01.8-1.71.20.21.0-0.81.7-1.6
Body weight0.83.47.62.42.12.8-1.81.9-0.32.0-0.81.0-1.7
Weight adjusted by age0.61.73.71.91.51.7-0.81.9-0.51.4-1.1-0.10.7
Bone surface1.42.76.32.12.51.3-2.11.11.00.0-1.62.0-1.3
Bone volume2.04.08.71.93.02.0-1.91.62.4-0.6-2.91.6-0.5
Breakpoint value in progressive ratio session0.10.20.80.00.10.6-0.10.3-0.20.6-0.00.9-0.2
Number of licking bursts0.10.30.6-0.8-0.7-0.70.8-0.60.1-0.40.4-0.50.6
Context. condit. distance diff. score0.91.12.50.71.41.3-0.21.60.20.6-1.4-0.31.2
Locomotion velocity, session 10.91.02.41.51.30.6-1.51.0-0.60.7-0.51.0-0.2
Locomotion distance, session 12.53.26.02.41.81.7-2.32.0-1.62.2-0.51.6-0.9
Locomotion velocity, session 20.30.31.10.5-0.2-0.3-0.3-0.3-1.00.60.90.1-0.5
Locomotion distance, session 21.82.54.72.01.31.2-2.21.3-1.61.90.11.8-1.5
Locomotion velocity, session 30.30.31.40.00.0-0.00.30.4-0.90.5-0.0-0.81.2
Locomotion distance, session 30.30.40.90.90.70.5-0.40.7-0.90.8-0.20.40.2
Stereotopy head waving bouts, day 31.21.44.40.01.50.3-0.30.91.3-0.9-2.1-0.32.0
Stereotopy head waving duration, day 31.41.75.3-0.51.20.50.20.91.7-1.0-2.2-0.72.3
Locomotion velocity, session 71.31.43.00.91.61.6-1.01.60.60.5-1.70.80.6
Locomotion distance, session 71.21.63.21.30.10.2-1.40.3-1.81.51.01.6-1.7
Stereotopy head waving bouts, day 71.21.44.1-0.70.70.31.00.61.0-0.8-1.6-1.82.0
Stereotopy head waving duration, day 71.61.94.6-0.80.60.61.20.71.7-1.1-1.9-1.92.1
Locomotion velocity, session 80.91.12.50.41.21.3-0.11.40.60.3-1.5-0.71.6
Locomotion distance, session 80.71.02.41.01.21.1-0.61.5-0.91.3-0.7-0.00.9
Degree of sensitization distance1.01.13.1-0.1-1.2-0.8-0.4-0.7-1.20.71.80.5-1.7
Degree of sensitization stereotypy0.80.93.0-0.80.30.21.10.30.6-0.6-0.9-1.71.4
Conditioned locomotion1.01.13.00.70.91.70.01.70.30.8-1.5-0.60.9
Cocaine response after cond. corrected0.60.91.9-1.4-1.3-1.01.0-1.20.3-0.90.6-0.60.2
Cocaine response after cond. not corrected0.50.71.6-1.3-1.2-0.80.9-1.00.2-0.70.6-0.70.1
Cocaine response before conditioning0.10.10.20.50.4-0.2-0.40.0-0.30.10.10.1-0.5
Saline control response0.40.52.10.90.9-0.1-0.70.7-1.40.7-0.10.30.3
Bone: connectivity density2.13.47.41.82.71.6-2.01.21.8-0.3-2.22.4-1.1
Bone: cortical apparent density0.10.20.8-0.6-0.3-0.10.50.10.1-0.2-0.4-0.70.9
Bone: cortical area0.81.33.11.31.71.2-1.11.20.40.2-1.51.3-0.4
Bone: cortical porosity0.20.20.80.80.1-0.1-0.3-0.4-0.20.00.30.6-0.9
Bone: cortical porosity0.30.41.20.90.3-0.2-0.6-0.40.1-0.30.11.1-1.0
Bone: cortical thickness0.30.51.70.91.10.4-0.60.50.1-0.0-0.91.3-0.1
Bone: cortical thickness1.51.86.61.31.9-0.2-1.8-0.10.4-0.6-0.82.6-1.2
Bone: cortical tissue density0.20.30.8-0.8-0.5-0.30.7-0.10.1-0.3-0.2-0.90.9
Condit. Reinf. active minus inactive responses0.60.62.1-0.50.50.90.10.91.0-0.2-1.4-0.21.0
Condit. Reinf. active-inactive response ratio0.91.02.7-0.70.61.30.30.91.6-0.4-1.6-0.40.9
Condit. Reinf. active responses0.60.71.50.91.01.0-1.11.2-0.40.8-0.80.5-0.2
Condit. Reinf. inactive responses1.21.63.41.91.20.5-1.81.2-1.51.4-0.11.0-0.8
Incentive salience index mean0.30.31.0-0.10.40.7-0.11.0-0.10.4-0.9-0.20.8
Condit. Reinf. lever presses0.91.33.21.30.71.0-1.11.5-1.71.8-0.20.6-0.1
Condit. Reinf. active minus inactive responses0.40.51.50.5-0.4-0.6-0.5-0.4-1.20.51.10.5-1.0
Condit. Reinf. active-inactive response ratio0.71.23.60.3-1.1-0.7-0.4-0.9-1.30.61.90.6-1.8
Condit. Reinf. active responses0.50.72.70.3-0.6-1.1-0.1-0.7-1.70.41.40.1-0.6
Condit. Reinf. inactive responses0.20.31.4-0.40.3-0.40.40.1-0.3-0.2-0.4-0.61.2
Condit. Reinf. lever presses0.40.61.3-0.7-0.9-1.20.7-0.7-0.6-0.50.6-0.80.8
Condit. Reinf. lever reinforcers received0.40.61.6-0.1-0.6-1.30.2-0.9-1.2-0.11.2-0.1-0.3
Conditioned reinforcement - actives0.10.41.6-0.5-0.3-1.30.4-0.90.3-1.20.1-0.20.3
Conditioned reinforcement - inactives0.00.10.30.20.3-0.1-0.40.2-0.50.30.00.00.0
Conditioned locomotion0.60.92.3-1.5-1.1-0.51.3-0.40.0-0.30.5-1.50.9
Patch foraging indifference point 0 sec0.20.62.80.80.4-0.0-0.60.5-1.71.10.60.3-0.4
Patch foraging indifference point AUC0.20.51.1-0.5-0.20.70.70.61.0-0.2-0.8-0.91.0
Delay disc. indifference point, 0s delay1.61.94.61.91.20.2-1.70.5-1.61.20.32.2-1.2
Delay disc. indifference point, 16s delay0.10.10.3-0.5-0.40.20.20.3-0.20.40.00.20.6
Delay disc. indifference point, 2s delay0.50.51.70.50.10.4-0.30.3-1.31.30.70.9-0.5
Delay disc. indifference point, 24s delay1.11.84.4-1.8-2.1-0.82.0-0.9-0.70.01.3-1.30.8
Delay disc. indifference point, 4s delay3.03.15.72.11.41.0-2.21.3-2.12.30.22.4-1.5
Delay disc. indifference point, 8s delay0.40.71.9-0.1-0.50.4-0.20.1-1.31.41.10.8-0.8
Indifference point function ln k0.41.33.00.70.1-1.5-0.7-1.1-1.70.21.60.7-1.6
Indifference point function log k0.41.33.00.70.1-1.5-0.7-1.1-1.70.21.60.7-1.6
Patch foraging total patch changes 0 sec0.41.14.41.10.50.0-0.90.6-2.11.50.80.6-0.7
Patch foraging total patch changes 12 sec0.10.10.3-0.2-0.2-0.3-0.1-0.3-0.1-0.00.40.5-0.2
Patch foraging total patch changes 18 sec0.51.22.31.21.11.2-1.41.40.00.9-0.91.50.0
Patch foraging total patch changes 24 sec0.62.04.91.31.52.2-1.41.80.61.2-1.31.5-0.6
Patch foraging total patch changes 6 sec0.30.51.30.50.51.0-0.51.0-0.61.1-0.20.8-0.4
Patch foraging time to switch 0 sec0.10.20.9-0.7-0.20.10.1-0.41.0-0.5-0.30.60.0
Patch foraging water rate 0 sec0.10.41.5-0.1-0.2-0.00.60.5-0.90.60.2-1.20.9
Patch foraging water rate 12 sec1.04.18.22.42.92.3-2.22.70.11.3-2.21.8-0.2
Patch foraging water rate 18 sec0.92.13.92.01.31.5-1.41.6-1.42.0-0.21.1-1.2
Patch foraging water rate 24 sec1.72.44.61.92.12.0-1.52.1-0.11.4-1.40.9-0.5
Patch foraging water rate 6 sec0.50.71.90.91.40.6-0.71.3-0.10.3-1.30.30.7
Seeking ratio, delayed vs. immediate footshock0.81.12.31.31.31.5-0.81.4-0.21.2-0.70.9-0.5
Distance traveled before self-admin0.10.20.80.30.80.2-0.70.30.20.0-0.30.9-0.4
Distance traveled after self-admin0.81.43.51.71.90.9-1.21.40.20.5-1.31.1-0.1
Extensor digitorum longus weight3.413.627.25.24.34.0-4.44.1-1.93.9-1.63.2-2.5
Bone: elastic displacement0.81.02.31.50.80.5-1.20.7-0.91.10.11.3-1.1
Bone: elastic work0.91.23.61.51.20.6-1.40.7-0.00.4-0.61.9-1.2
Bone: endosteal estimation0.20.51.10.70.81.0-0.40.80.60.3-0.80.5-0.6
Bone: endosteal perimeter0.71.74.51.21.62.1-1.11.90.51.0-1.50.4-0.3
Epididymis fat weight0.10.31.7-0.10.30.40.1-0.31.3-0.5-0.3-0.2-0.4
Delta time in closed arm before/after self-admin3.02.95.52.11.41.2-2.31.3-1.11.7-0.12.3-2.0
Delta time in open arm before/after self-admin5.05.910.2-3.2-2.6-2.52.9-3.01.8-2.91.1-2.01.2
Diff in mean of infusions in LGA sessions0.71.22.5-1.3-1.6-0.41.6-0.5-0.60.20.9-1.61.1
Delay discount exponential model param1.01.34.4-0.30.4-0.40.5-0.42.1-2.0-1.3-1.20.9
Extinction: sum of active levers before priming0.71.12.8-0.9-0.31.21.21.00.90.3-0.9-1.41.7
Active lever presses in extinction session 60.40.41.20.5-0.21.0-0.20.60.80.3-0.31.1-0.9
Bone: final force0.91.43.91.41.40.8-1.40.50.40.2-0.72.0-1.6
Bone: final moment1.11.84.71.61.50.8-1.60.50.30.3-0.52.2-2.1
Food consumed during 24 hour testing period0.30.72.5-1.0-0.4-1.10.7-0.60.1-0.9-0.1-0.51.6
Glucose0.40.61.4-0.5-0.70.20.30.1-1.11.21.1-1.00.1
Heart weight0.40.71.60.81.00.4-1.20.00.8-0.2-0.31.0-1.3
Delay discount hyperbolic model param1.21.64.8-0.60.2-0.50.7-0.52.2-2.1-1.3-1.41.1
Intermittent access intake day 1-15 change0.10.51.10.80.91.0-0.11.00.10.4-1.10.20.5
Intermittent access intake escalation0.10.61.40.70.81.20.01.10.20.5-1.10.20.6
Intermittent access intake escalation 20.61.03.21.20.21.6-0.11.3-1.01.80.1-0.2-0.4
Intermitt. access day 1 inactive lever presses0.33.67.42.02.12.7-2.42.60.02.0-1.31.0-1.0
Intermitt. access day 15 inactive lever presses0.42.17.70.51.12.8-0.32.20.91.3-1.7-1.00.8
Intermitt. access escalation Index0.10.20.8-0.9-0.3-0.20.7-0.50.2-0.40.00.00.4
Intermittent access day 1 total infusions0.10.41.3-1.1-0.9-0.50.5-0.70.4-0.50.5-0.3-0.0
Intermittent access day 15 total infusions0.20.41.0-0.30.21.00.50.51.0-0.1-1.0-0.00.7
Intermittent access terminal intake (last 3 days)0.40.71.6-0.40.41.10.60.81.1-0.1-1.3-0.51.1
Intermittent access total infusions0.30.41.0-0.9-0.30.20.8-0.11.0-0.6-0.5-0.40.5
Intermittent access day 1 locomotion0.20.30.9-1.0-0.6-0.20.6-0.30.7-0.50.0-0.90.3
Intermittent access day 15 total locomotion0.31.12.0-1.2-0.6-0.61.3-0.81.4-1.4-0.5-1.21.2
Intermittent access total locomotion1.51.83.7-1.9-0.9-0.31.8-0.51.4-1.2-0.5-1.91.6
Intermittent access standard deviation0.21.22.31.31.41.5-0.91.30.00.9-1.11.1-0.1
Left kidney weight0.43.25.02.21.72.2-2.21.8-0.51.9-0.51.8-1.9
Right kidney weight0.64.47.82.81.92.2-2.51.9-1.62.70.21.4-2.3
Cocaine induced anxiety0.51.44.3-0.2-1.2-1.30.3-1.0-2.00.72.1-1.2-0.3
Post-drug Anxiety0.10.20.70.10.1-0.6-0.2-0.3-0.4-0.10.3-0.90.2
Baseline Anxiety1.72.88.6-0.81.20.00.30.22.9-2.5-2.80.01.9
Tail length0.21.13.20.20.91.20.30.91.8-0.5-1.7-0.80.9
Length with tail0.21.13.01.11.31.7-0.51.50.50.7-1.2-0.70.3
Length without tail0.21.13.21.20.51.0-0.71.1-1.61.80.4-0.5-0.4
Times rat made contact with spout0.80.94.00.2-0.4-1.20.0-0.6-2.00.61.5-0.4-0.3
Lifetime Intake0.40.51.4-1.0-0.30.30.8-0.11.2-0.6-0.6-0.60.7
Liver weight, left0.61.14.0-0.1-0.61.30.41.2-1.32.00.6-0.90.0
Liver weight, right0.71.35.2-0.80.3-0.10.90.61.0-0.9-1.4-1.42.3
Locomotor activity0.40.61.91.41.0-0.4-1.10.2-0.80.1-0.21.0-0.5
Locomotor testing distance1.12.66.72.62.10.4-2.31.3-1.21.0-0.82.1-0.8
Locomotor testing rearing0.62.25.22.01.1-0.6-1.7-0.1-1.80.70.72.3-2.0
Locomotion in novel chamber0.81.12.80.60.20.9-0.70.5-1.41.70.81.2-1.5
Locomotion in novel chamber post-restriction0.30.92.9-0.3-0.8-0.9-0.1-1.0-1.20.31.70.2-1.5
Fecal boli incidents, locomotor time 10.20.63.20.20.20.2-1.0-0.2-0.00.20.31.8-1.1
Change in fecal boli incidents, locomotor task0.60.63.10.80.3-0.4-0.30.4-1.81.00.6-1.0-0.0
Time >=10cm from walls, locomotor time 11.31.64.60.70.62.1-1.02.0-0.42.0-0.61.0-0.0
Bouts of movement, locomotor time 11.51.95.1-0.7-2.1-1.31.3-1.9-0.9-0.22.2-0.7-0.9
Total resting periods, locomotor time 11.61.84.6-0.5-2.1-1.41.3-1.8-1.0-0.22.2-0.9-0.5
Rest time, locomotor task time 10.20.30.80.9-0.5-0.3-0.1-0.4-0.70.30.7-0.3-0.2
Distance moved, locomotor task time 10.10.41.20.01.10.2-0.70.30.5-0.2-0.60.7-0.8
Vertical activity count, locomotor time 10.11.02.8-0.11.60.2-1.20.70.8-0.4-1.31.7-0.2
Time >=10cm from walls, locomotor time 20.10.31.00.21.0-0.3-0.80.4-0.1-0.3-0.70.70.6
Bouts of movement, locomotor time 20.30.92.4-1.5-0.9-0.91.1-0.7-0.0-0.60.4-1.11.3
Total resting periods, locomotor time 20.20.92.1-1.5-1.0-1.01.1-0.8-0.2-0.60.6-1.11.2
Rest time, locomotor task time 20.20.41.00.20.30.9-0.10.90.20.4-0.8-0.51.0
Distance moved, locomotor task time 20.30.40.9-0.6-0.3-0.70.5-1.00.5-0.80.5-0.2-0.7
Vertical activity count, locomotor time 20.20.41.30.30.70.1-1.00.20.00.2-0.11.1-0.9
Light reinforcement 10.42.04.52.11.81.2-1.71.7-1.21.5-0.70.7-0.1
Light reinforcement 20.20.41.3-0.1-0.70.20.50.2-0.70.70.6-1.10.4
Bone: marrow area0.20.51.10.80.71.0-0.40.80.50.3-0.80.6-0.6
Bone: maximum diameter0.20.41.30.30.70.9-0.20.80.8-0.2-1.10.50.3
Bone: maximum force1.12.24.41.62.11.5-1.41.31.00.1-1.71.9-1.2
Bone: maximum moment1.32.44.41.82.11.5-1.61.20.80.3-1.42.1-1.7
Mean time between licks in bursts0.31.94.7-0.9-2.1-1.80.7-1.7-1.0-0.22.20.4-1.0
Mean num. licks in bursts0.10.41.10.80.60.1-0.80.4-1.10.70.20.3-0.5
Cd content in liver0.60.72.41.50.70.6-0.60.9-0.80.9-0.20.8-0.4
Co content in liver1.01.24.0-0.0-0.8-1.1-0.5-1.4-0.6-0.21.60.9-2.0
Cu content in liver0.80.93.01.00.70.3-1.50.1-0.40.60.41.3-1.7
Fe content in liver0.20.20.70.60.80.1-0.60.10.2-0.2-0.50.7-0.1
K content in liver0.80.82.6-0.9-0.70.21.10.10.9-0.6-0.7-1.21.6
Mg content in liver0.70.81.9-0.8-0.3-0.20.8-0.11.1-1.1-0.9-1.21.4
Mn content in liver0.40.51.2-0.9-0.70.70.60.20.70.1-0.2-1.10.8
Na content in liver1.11.33.61.31.70.1-1.90.4-0.20.1-0.61.8-0.9
Rb content in liver1.01.12.7-0.9-1.2-1.30.1-1.6-0.5-0.41.70.3-1.1
Se content in liver0.80.92.20.51.50.5-1.10.21.4-0.9-1.40.4-0.2
Sr content in liver1.91.63.11.10.81.7-1.21.3-0.71.8-0.21.7-1.3
Zn content in liver0.10.10.5-0.10.30.2-0.10.10.7-0.4-0.40.10.0
Bone: minimum diameter0.20.41.00.60.81.0-0.41.00.10.5-0.80.1-0.5
Time in familiar zone, hab. session 11.11.23.31.11.80.9-0.91.01.1-0.3-1.60.60.5
Time in novel zone, hab. session 10.50.51.1-0.5-1.1-1.00.4-0.7-1.00.11.0-0.2-0.5
Total zone transitions, hab. session 10.30.41.11.00.50.1-0.90.4-0.80.60.10.9-0.4
Total locomotion distance, hab. session 11.31.94.01.81.91.1-1.32.0-1.11.3-1.20.20.6
Locomotion velocity, hab. session 10.91.32.71.41.50.9-1.01.6-1.31.3-0.80.10.7
Time in familiar zone, hab. session 20.50.61.21.00.41.1-0.90.8-0.31.1-0.00.7-0.7
Time in novel zone, hab. session 20.80.82.2-1.2-0.2-1.20.9-1.00.7-1.5-0.2-0.50.8
Total zone transitions, hab. session 22.22.86.32.21.01.0-1.91.4-2.52.40.61.0-1.2
Total locomotion distance, hab. session 22.12.84.82.22.11.3-1.92.2-2.12.1-0.60.30.2
Locomotion velocity, hab. session 21.92.54.32.01.91.1-1.82.1-2.02.0-0.50.20.3
Novel to familiar place preference ratio0.20.30.6-0.3-0.1-0.60.6-0.70.4-0.80.1-0.5-0.4
Novelty place preference0.50.71.4-0.8-0.6-1.01.1-1.20.4-1.00.6-0.9-0.3
Time in novel zone, NPP test0.40.51.2-0.6-0.3-1.00.8-1.10.4-1.00.3-0.5-0.3
Total zone transitions, NPP test0.91.33.61.30.70.6-1.31.2-1.91.70.11.1-0.2
Total locomotion distance, NPP test1.52.05.01.61.21.0-1.41.8-2.22.2-0.00.5-0.0
Locomotion velocity, NPP test1.31.94.91.51.01.0-1.31.6-2.22.20.20.4-0.0
Intraocular pressure1.52.57.0-1.2-2.1-1.71.0-2.0-1.2-0.12.6-1.1-1.2
Delta distance traveled before/after self-admin0.90.92.41.21.30.9-0.61.30.60.1-1.60.00.7
Delta ambulatory time before/after self-admin0.71.34.41.21.30.4-0.31.01.3-0.8-2.10.01.3
Parametrial fat weight0.51.22.11.41.40.6-1.41.2-1.31.40.1-0.3-0.1
Pavlov. Cond. lever latency0.50.62.0-0.30.11.00.50.71.4-0.3-1.1-0.71.0
Pavlov. Cond. magazine entry latency0.70.91.91.00.5-0.4-1.1-0.2-1.40.81.01.0-1.4
Pavlov. Cond. change in total contacts0.40.51.10.70.7-0.2-0.8-0.1-1.00.50.40.9-0.9
Pavlov. Cond. index score0.81.02.31.20.7-0.2-1.20.1-1.50.90.71.2-1.4
Pavlov. Cond. latency score0.81.12.91.10.6-0.3-1.20.1-1.71.00.71.2-1.3
Pavlov. Cond. lever contacts1.21.54.20.90.1-1.1-1.0-0.7-2.00.71.51.3-1.7
Pavlov. Cond. magazine entry number1.11.43.2-1.2-0.40.11.30.01.8-1.3-1.2-1.21.8
Pavlov. Cond. intertrial magazine entries0.91.14.9-0.5-0.1-1.40.4-1.21.5-2.2-0.4-0.00.2
Pavlov. Cond. lever-magazine prob. diff.0.91.22.41.20.7-0.3-1.3-0.0-1.60.90.71.3-1.5
Pavlov. Cond. response bias0.91.12.61.00.4-0.5-1.1-0.3-1.60.91.10.9-1.6
Pavlov. Cond. lever latency0.50.72.10.10.91.4-0.41.01.10.2-1.30.20.3
Pavlov. Cond. magazine entry latency0.50.71.4-1.0-1.0-1.10.8-1.20.4-1.10.6-0.60.4
Pavlov. Cond. change in total contacts0.92.15.2-1.0-2.0-2.31.3-2.0-0.7-1.01.8-0.9-0.0
Pavlov. Cond. index score0.81.33.2-0.9-1.5-1.81.0-1.5-0.5-0.91.4-1.00.2
Pavlov. Cond. latency score0.81.33.1-0.9-1.4-1.81.1-1.5-0.3-1.11.1-1.10.6
Pavlov. Cond. lever contacts0.40.62.0-0.1-0.8-1.40.2-0.9-1.0-0.31.1-0.1-0.3
Pavlov. Cond. magazine entry number1.01.32.61.01.61.6-1.01.60.30.8-1.41.0-0.1
Pavlov. Cond. intertrial magazine entries0.10.10.5-0.30.30.10.30.20.4-0.2-0.6-0.20.7
Pavlov. Cond. lever-magazine prob. diff.1.11.63.9-1.1-1.6-2.01.1-1.7-0.3-1.21.3-1.20.4
Pavlov. Cond. response bias0.91.33.3-0.5-1.5-1.60.6-1.5-1.1-0.31.8-0.2-0.7
Time in closed arm before self-admin0.10.21.20.60.10.00.1-0.2-0.20.10.3-1.1-0.3
Time in closed arm after self-admin2.02.35.32.31.41.2-2.01.0-1.01.50.01.5-2.0
Time in open arm before self-admin1.72.15.61.31.52.2-1.12.4-0.31.7-1.40.90.2
Time in open arm after self-admin0.60.71.8-1.3-0.40.21.0-0.11.3-0.7-0.5-0.51.1
Bone: periosteal estimation0.41.01.81.11.31.3-0.71.10.60.3-1.30.8-0.5
Bone: periosteal perimeter0.81.53.71.21.61.9-1.01.70.50.8-1.40.5-0.2
Bone: post-yield work1.22.15.50.92.21.7-0.91.61.7-0.3-2.41.0-0.0
Progressive ratio test 1 active lever presses0.50.92.7-1.4-0.3-0.50.5-0.71.7-1.5-0.50.30.3
Progressive ratio test 1 breakpoint0.61.03.2-1.5-0.3-0.50.6-0.81.8-1.7-0.60.30.4
Progressive ratio test 1 inactive lever presses0.30.81.90.20.31.3-1.20.8-0.31.40.30.3-1.3
Progressive ratio test 2 active lever presses0.60.93.1-0.80.4-0.40.3-0.51.8-1.6-1.1-0.10.8
Progressive ratio test 2 breakpoint0.71.03.4-0.80.4-0.40.3-0.51.9-1.7-1.1-0.10.8
Progressive ratio test 2 inactive lever presses0.00.10.7-0.7-0.1-0.10.1-0.20.2-0.20.1-0.8-0.2
Incentive Sensitization - Responses0.61.74.2-1.1-0.4-1.31.2-1.21.3-2.1-0.5-1.61.3
Incentive Sensitization - Breakpoint0.61.43.5-1.0-0.3-1.11.1-1.01.3-1.9-0.5-1.61.3
Sum of active levers in priming session hrs 5-62.52.35.5-2.3-0.9-0.12.0-0.42.3-1.7-0.9-1.31.6
Progressive ratio0.61.94.8-1.9-1.70.12.2-0.30.7-0.4-0.0-1.81.8
Food seeking constrained by brief footshock1.51.94.01.61.32.0-1.11.61.40.5-1.61.5-0.1
Seeking ratio, punishment vs. effort1.43.17.82.82.31.4-2.41.5-0.00.9-1.01.9-1.7
Retroperitoneal fat weight0.62.76.91.91.62.1-1.61.7-1.62.60.20.2-1.0
Reaction time number correct0.20.61.2-0.8-0.9-1.10.9-0.9-0.3-0.60.6-0.70.3
Reaction time mean minus median0.21.13.60.3-1.1-0.40.2-0.8-1.30.81.9-0.5-1.6
Reaction time mean minus median AUC0.21.44.40.4-1.1-0.9-0.0-1.3-1.20.42.10.1-2.1
Reaction time num false alarms1.42.45.71.82.41.3-2.31.20.30.5-1.41.8-1.0
Reaction time num false alarms AUC0.81.84.71.52.21.1-2.01.10.40.4-1.31.5-0.8
Reaction time trials correct on left0.20.61.2-0.8-0.9-1.10.9-0.9-0.3-0.60.6-0.70.3
Reaction time trials on left0.10.51.0-0.7-0.9-1.00.8-0.9-0.3-0.60.6-0.70.2
Reaction time mean0.81.85.40.9-0.90.2-0.0-0.1-2.31.92.1-0.7-1.5
Reaction time mean AUC0.51.13.10.7-0.80.20.1-0.1-1.81.51.6-0.8-1.2
Median of all reaction times0.91.44.50.7-0.90.20.10.0-2.11.81.8-0.8-1.1
Reaction time omissions0.20.41.50.70.40.9-0.30.20.90.0-0.30.2-1.2
Reaction time false alarm rate1.72.45.11.72.21.6-2.31.40.30.8-1.21.8-1.1
Reaction time premature initiation rate0.50.92.4-0.80.1-1.00.9-0.60.5-1.4-0.6-0.91.5
Reaction time premature initiations0.51.42.9-1.2-0.4-1.51.4-1.10.4-1.6-0.3-1.21.7
Std. dev. reaction times0.41.33.41.3-0.30.5-0.60.2-1.61.61.4-0.0-1.8
Reaction time trials completed0.10.51.0-0.7-0.9-1.00.8-0.9-0.3-0.60.6-0.70.2
Reaction time trials AUC0.10.40.8-0.5-0.7-0.90.7-0.7-0.3-0.50.5-0.50.2
Run reversals in cocaine runway, females0.60.72.21.00.4-0.0-1.0-0.1-0.20.20.31.5-1.5
Run reversals in cocaine runway, males0.30.30.80.90.50.2-0.4-0.10.4-0.3-0.20.8-0.9
Latency to leave start box in cocaine runway0.40.51.2-0.20.60.0-0.4-0.11.1-1.0-1.11.00.4
Latency to leave start box in cocaine runway, F0.30.31.0-0.50.10.4-0.00.11.0-0.6-0.90.30.8
Latency to leave start box in cocaine runway, M0.40.41.50.20.6-0.6-0.4-0.40.4-0.8-0.41.2-0.6
Std. dev. time between licks in bursts0.10.10.5-0.2-0.2-0.70.1-0.3-0.3-0.30.20.70.1
Total sessions with >9 infusions0.40.41.1-0.9-0.30.30.80.20.7-0.3-0.5-1.01.0
Short access day 1 total inactive lever presses0.20.41.20.21.10.2-0.80.40.9-0.5-1.00.40.3
Short access day 10 total inactive lever presses0.31.95.32.31.21.5-1.41.5-1.11.8-0.0-0.0-1.3
Short access day 1 total infusions0.10.20.7-0.20.30.9-0.30.60.40.5-0.20.4-0.4
Short access day 10 total infusions0.40.61.6-1.1-0.20.60.80.51.0-0.2-0.8-0.81.2
Short access total infusions0.20.20.6-0.8-0.00.60.20.40.80.0-0.5-0.20.5
Short access day 1 locomotion0.60.93.00.50.61.7-0.41.6-0.31.6-0.4-0.10.1
Short access day 10 total locomotion0.83.16.3-2.3-2.5-1.42.4-1.80.6-1.21.3-2.10.9
Short access total locomotion0.40.62.2-0.8-0.40.80.80.50.50.3-0.3-1.50.9
One hour access (0.3 mA shock)1.11.32.6-1.2-1.0-1.01.5-0.91.2-1.6-0.3-1.20.9
Compulsive drug intake0.40.51.20.2-1.1-0.30.7-0.2-1.10.61.0-0.8-0.4
One hour access (shock baseline)0.41.03.5-0.80.10.10.7-0.11.9-1.4-1.3-0.41.1
Social response proportion1.11.44.3-1.0-0.7-2.10.3-1.9-0.5-1.01.50.4-0.7
Social responses1.11.45.7-1.1-0.5-2.40.5-1.8-0.4-1.41.0-0.30.4
Social time2.23.56.0-2.1-1.9-2.42.4-1.6-0.1-1.80.8-2.22.0
Soleus weight2.36.715.53.92.92.7-3.02.7-1.72.8-0.92.2-1.9
Bone: stiffness0.40.72.40.41.00.5-0.30.21.5-1.0-1.40.7-0.3
Tibialis anterior weight1.03.68.12.32.12.8-1.42.8-0.72.3-1.40.3-0.1
Time to tail flick, vehicle, before self-admin1.61.95.9-0.8-0.7-2.21.0-2.21.1-2.40.40.3-0.3
Time to tail flick, vehicle, after self-admin0.20.30.7-0.2-0.8-0.40.1-0.80.2-0.20.80.4-0.9
Time to tail flick, test, before self-admin0.91.14.6-0.30.60.1-0.6-0.52.2-1.4-1.11.2-0.3
Time to tail flick, test, after self-admin1.71.87.1-0.31.1-0.1-0.3-0.32.7-2.2-2.00.40.6
Delta time to tail flick, vehicle, before/after SA0.70.72.30.80.41.5-0.81.4-0.01.2-0.50.3-0.0
Delta time to tail flick, test, before/after SA0.10.20.60.10.4-0.10.10.4-0.1-0.2-0.5-0.60.7
Tibia length0.10.20.8-0.2-0.90.20.4-0.30.3-0.00.4-0.2-0.6
Ambulatory time before self-admin0.10.30.90.50.90.4-0.80.5-0.00.4-0.20.7-0.6
Ambulatory time after self-admin1.32.16.12.12.50.7-1.71.40.30.2-1.61.5-0.3
Bone: tissue strength0.30.30.80.40.60.8-0.20.90.10.4-0.8-0.10.3
Total heroin consumption0.20.20.6-0.00.1-0.20.6-0.10.6-0.8-0.60.50.1
Bone: trabecular number3.56.614.42.53.82.9-2.72.52.40.1-3.52.4-0.6
Bone: trabecular spacing2.03.06.3-2.3-2.3-1.52.5-1.6-0.3-0.91.2-1.81.5
Bone: trabecular thickness1.11.52.81.51.71.2-1.51.11.4-0.2-1.60.6-0.6
Bone: trabecular tissue density0.81.55.5-1.0-0.7-0.81.2-0.30.5-0.9-0.3-2.12.3
Water consumed over 24 hours0.40.82.2-0.9-0.5-1.50.8-0.8-0.5-0.80.4-0.71.2
Number of responses in last shaping day0.40.51.30.20.4-0.0-1.0-0.2-0.80.70.81.0-1.2