Homer3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 PL mRNA stability Homer3 0.04 0.03 4.8e-03 0.02 0.01 0 0.01 1.5e-03 4.1e-02 3.7e-01 2.8e-02
2 Adipose mRNA stability Homer3 0.03 0.02 3.3e-03 0.01 0.01 0.01 0.01 5.9e-02 2.3e-02 3.5e-02 7.1e-02
3 Brain alternative polyA NM_053310.1 0.05 0.03 1.1e-03 0.02 0.02 0.02 0.03 3.5e-03 2.7e-03 2.6e-03 2.1e-03
4 NAcc gene expression Homer3 0.08 0.04 1.1e-07 0.05 0.05 0.05 0.05 1.5e-08 3.6e-08 1.2e-07 2.5e-08
5 Brain alternative polyA XM_006252890.5 0.05 0.04 1.0e-03 0.04 0.03 0.03 0.03 1.8e-04 1.7e-03 9.4e-04 6.5e-04
6 NAcc mRNA stability Homer3 0.05 0.03 3.7e-04 0.03 0.02 0.03 0.03 2.8e-05 5.3e-04 4.1e-05 3.2e-05
7 Liver gene expression Homer3 0.24 0.1 2.9e-14 0.09 0.08 0.08 0.09 4.6e-10 6.0e-09 2.4e-09 1.0e-09
8 Adipose isoform ratio XM_039094433.2 0.06 0.04 5.0e-04 0.03 0.02 0.02 0.02 3.9e-04 3.2e-03 1.8e-03 1.1e-03
9 Adipose alternative polyA XM_039094433.2 0.06 0.03 3.5e-04 0.02 0.02 0.02 0.02 4.5e-03 1.6e-03 1.2e-03 4.3e-03
10 IC gene expression Homer3 0.32 0.15 2.0e-04 0.15 0.09 0.13 0.14 1.0e-06 9.9e-05 4.1e-06 1.6e-06
11 Liver isoform ratio XM_006252890.5 0.1 0.05 2.1e-06 0.03 0.02 0.02 0.02 7.6e-04 3.1e-03 5.2e-03 1.3e-03
12 Adipose gene expression Homer3 0.05 0.03 2.3e-04 0.02 0.01 0.01 0.01 5.4e-03 9.1e-03 2.4e-02 2.6e-02
13 Brain mRNA stability Homer3 0.13 0.07 2.8e-08 0.1 0.09 0.09 0.1 5.1e-10 1.2e-08 4.5e-09 2.1e-09
14 pVTA gene expression Homer3 0.06 0.04 6.4e-03 0.03 0.01 0.01 0.02 3.8e-03 2.2e-02 2.1e-02 7.7e-03
15 Adipose alternative polyA XM_006252890.5 0.06 0.04 4.2e-04 0.01 0.02 0.01 0.02 7.1e-03 1.6e-03 1.3e-02 4.3e-03
16 Brain alternative TSS XM_006252890.5 0.03 0.02 9.6e-03 0.01 0.01 0 0.01 1.4e-02 1.2e-02 1.1e-01 2.3e-02
17 Brain alternative TSS XM_063275272.1 0.03 0.02 8.5e-03 0.01 0.02 0 0.01 1.3e-02 1.0e-02 1.0e-01 2.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
Bone: apparent density5.69.612.72.72.4-3.43.43.33.3-3.4-3.3-3.43.63.4-1.23.23.22.8-2.82.8
Area under the delay curve0.10.10.6-0.2-0.30.4-0.4-0.2-0.40.10.30.1-0.1-0.00.5-0.8-0.80.3-0.20.2
BMI with tail0.51.77.32.71.9-1.41.21.11.1-1.1-1.3-1.41.31.0-0.91.21.21.2-0.30.3
BMI without tail0.82.59.43.12.5-1.81.41.51.3-1.5-1.5-1.51.11.6-1.51.31.31.3-0.20.2
Body weight3.214.228.25.34.8-4.03.93.53.6-3.5-4.1-4.23.63.6-3.33.63.63.8-2.32.2
Weight adjusted by age0.71.13.41.81.4-1.20.81.00.8-1.6-1.1-1.01.11.4-0.90.60.60.40.1-0.2
Bone surface2.54.66.42.31.6-2.42.32.32.2-2.3-2.4-2.42.52.3-0.72.12.12.0-1.91.9
Bone volume4.07.210.12.92.3-3.02.92.82.8-3.0-3.0-3.03.23.0-1.12.72.72.4-2.22.1
Breakpoint value in progressive ratio session0.30.41.50.2-0.41.2-0.2-1.0-0.40.70.20.3-0.3-0.70.4-0.3-0.3-0.50.8-0.8
Number of licking bursts0.10.20.7-0.8-0.20.0-0.40.2-0.5-0.10.40.2-0.5-0.50.3-0.3-0.30.6-0.80.8
Context. condit. distance diff. score0.20.21.4-1.20.0-0.3-0.4-0.0-0.30.00.40.4-0.3-0.1-0.60.10.10.3-0.70.8
Locomotion velocity, session 11.81.92.8-1.0-1.21.3-1.7-1.5-1.61.51.61.5-1.5-1.71.4-1.3-1.3-1.11.2-1.2
Locomotion distance, session 10.50.61.8-1.0-1.20.4-0.9-0.5-0.90.40.80.7-0.6-0.61.3-0.8-0.8-0.50.00.0
Locomotion velocity, session 20.40.40.90.10.30.3-0.8-0.9-0.90.80.80.6-0.9-0.9-0.1-0.6-0.6-0.10.7-0.7
Locomotion distance, session 20.60.82.4-1.1-1.50.9-0.8-0.9-0.70.90.70.7-0.7-0.81.5-0.7-0.7-0.70.3-0.2
Locomotion velocity, session 32.22.53.9-2.0-1.41.5-1.9-1.9-1.81.71.91.9-1.9-2.00.5-1.3-1.3-1.31.0-1.0
Locomotion distance, session 30.30.30.6-0.2-0.0-0.80.50.60.5-0.6-0.5-0.40.60.70.20.30.30.3-0.80.8
Stereotopy head waving bouts, day 30.81.05.1-2.2-0.91.1-0.9-1.1-1.01.11.00.8-1.1-1.1-0.6-0.1-0.10.2-0.80.8
Stereotopy head waving duration, day 30.70.83.3-1.8-0.61.0-1.0-1.0-1.20.91.00.9-1.0-1.0-0.8-0.4-0.40.2-0.50.5
Locomotion velocity, session 71.51.72.5-1.1-1.41.3-1.1-1.5-1.11.41.31.3-1.1-1.21.2-1.6-1.6-1.41.1-1.1
Locomotion distance, session 70.30.41.3-0.5-1.10.9-0.4-0.6-0.50.80.50.5-0.2-0.41.1-0.5-0.5-0.60.3-0.3
Stereotopy head waving bouts, day 70.10.20.9-0.40.3-0.00.30.10.3-0.1-0.2-0.20.20.1-0.90.10.10.6-0.70.7
Stereotopy head waving duration, day 70.10.21.2-0.60.30.4-0.2-0.4-0.20.50.30.3-0.3-0.4-1.1-0.3-0.30.2-0.10.1
Locomotion velocity, session 84.45.38.1-2.7-2.22.3-2.8-2.5-2.82.42.82.7-2.6-2.41.3-2.1-2.1-1.81.4-1.4
Locomotion distance, session 80.20.31.1-1.0-0.80.2-0.6-0.6-0.50.50.60.6-0.5-0.51.0-0.1-0.1-0.2-0.30.3
Degree of sensitization distance0.80.91.8-0.5-0.91.3-1.0-1.1-1.01.10.90.9-0.9-1.10.7-0.6-0.6-0.80.9-0.9
Degree of sensitization stereotypy0.50.61.00.40.8-0.80.90.80.8-0.8-0.8-0.70.80.7-1.00.20.20.8-0.80.8
Conditioned locomotion0.30.30.6-0.10.3-0.40.60.20.7-0.4-0.7-0.60.30.1-0.50.70.70.7-0.80.8
Cocaine response after cond. corrected0.20.21.3-0.50.5-0.20.50.10.50.1-0.5-0.30.0-0.1-1.10.50.50.4-0.60.6
Cocaine response after cond. not corrected0.40.41.3-1.1-0.50.7-0.5-0.8-0.51.10.60.7-0.9-0.9-0.5-0.4-0.4-0.50.2-0.2
Cocaine response before conditioning2.83.44.9-1.0-1.91.8-2.2-1.7-2.11.72.22.0-1.7-1.51.7-2.1-2.1-1.71.7-1.7
Saline control response0.00.10.2-0.3-0.2-0.3-0.30.3-0.4-0.20.10.1-0.00.10.5-0.0-0.0-0.30.1-0.1
Bone: connectivity density4.46.99.82.42.1-3.12.73.02.7-3.1-2.7-2.83.03.0-0.62.82.82.3-2.22.2
Bone: cortical apparent density0.30.43.30.2-0.50.3-0.1-0.3-0.10.30.00.1-0.2-0.01.8-0.5-0.5-0.70.8-0.8
Bone: cortical area6.09.217.04.13.4-2.93.52.73.5-2.6-3.3-3.23.23.0-2.73.33.32.4-1.61.5
Bone: cortical porosity0.20.20.90.3-0.40.5-0.3-0.2-0.20.20.30.2-0.2-0.10.7-1.0-1.0-0.30.5-0.5
Bone: cortical porosity0.10.10.50.3-0.30.3-0.1-0.10.00.10.10.0-0.00.00.5-0.7-0.7-0.00.1-0.1
Bone: cortical thickness5.59.212.93.43.2-2.83.62.83.6-2.7-3.4-3.33.23.1-2.73.23.22.7-2.12.1
Bone: cortical thickness7.28.511.41.52.5-2.53.32.73.3-2.6-3.1-3.02.93.0-2.43.43.43.0-3.23.2
Bone: cortical tissue density0.30.53.70.0-0.60.4-0.2-0.4-0.20.40.20.2-0.3-0.21.9-0.7-0.7-0.80.8-0.8
Condit. Reinf. active minus inactive responses2.02.33.90.91.3-1.61.51.31.5-1.6-1.5-1.61.51.6-1.61.11.11.9-2.02.0
Condit. Reinf. active-inactive response ratio4.04.25.51.31.6-2.32.21.92.2-2.1-2.2-2.22.32.3-1.61.81.82.1-2.32.3
Condit. Reinf. active responses1.31.62.90.81.2-1.21.11.01.2-1.3-1.1-1.31.11.3-1.60.80.81.7-1.71.7
Condit. Reinf. inactive responses0.10.10.20.30.20.1-0.3-0.1-0.40.00.40.3-0.4-0.1-0.2-0.1-0.1-0.00.4-0.4
Incentive salience index mean1.01.22.71.01.0-1.01.10.71.1-1.0-1.1-1.30.90.9-1.20.70.71.7-1.51.5
Condit. Reinf. lever presses0.30.41.50.80.6-0.20.6-0.00.6-0.2-0.6-0.70.1-0.0-0.40.60.61.2-0.90.9
Condit. Reinf. active minus inactive responses0.10.10.4-0.2-0.50.2-0.3-0.3-0.40.20.30.30.10.10.6-0.1-0.1-0.60.4-0.4
Condit. Reinf. active-inactive response ratio0.10.20.40.50.6-0.30.30.10.3-0.2-0.3-0.30.50.4-0.70.60.60.3-0.20.1
Condit. Reinf. active responses1.42.02.9-1.3-1.61.1-1.6-1.2-1.71.31.61.6-1.1-1.01.7-1.3-1.3-1.61.3-1.3
Condit. Reinf. inactive responses4.55.87.4-2.2-2.62.1-2.6-2.0-2.72.32.72.7-2.3-2.22.4-2.4-2.4-2.72.2-2.2
Condit. Reinf. lever presses1.01.42.2-0.5-0.71.2-1.4-1.4-1.51.51.31.3-1.1-1.11.0-1.0-1.0-1.21.4-1.4
Condit. Reinf. lever reinforcers received0.91.31.9-0.8-1.11.0-1.3-1.1-1.31.21.21.3-0.9-0.81.3-0.9-0.9-1.41.2-1.2
Conditioned reinforcement - actives0.71.32.71.61.6-1.51.01.41.0-1.2-1.0-1.01.01.1-1.31.01.00.8-0.40.4
Conditioned reinforcement - inactives4.66.813.73.03.6-2.82.52.72.6-2.6-2.5-2.52.22.4-3.72.62.62.2-1.41.4
Conditioned locomotion0.60.71.70.91.3-1.10.61.10.6-1.1-0.6-0.60.51.0-1.20.90.90.7-0.40.3
Patch foraging indifference point 0 sec0.20.41.81.31.10.1-0.1-0.50.00.40.1-0.10.2-0.3-1.20.70.70.8-0.10.1
Patch foraging indifference point AUC0.81.12.7-0.4-0.91.6-0.8-1.5-0.81.40.80.7-0.9-0.81.2-0.9-0.9-0.81.2-1.1
Delay disc. indifference point, 0s delay2.83.14.9-2.2-2.01.9-2.0-1.8-2.01.81.91.7-1.8-1.71.8-2.0-2.0-1.00.6-0.6
Delay disc. indifference point, 16s delay0.91.01.7-0.7-1.11.2-1.3-1.0-1.30.91.21.0-0.8-0.71.2-1.1-1.1-0.60.6-0.5
Delay disc. indifference point, 2s delay0.30.30.8-0.7-0.70.7-0.4-0.6-0.50.60.20.1-0.3-0.40.7-0.9-0.90.1-0.30.3
Delay disc. indifference point, 24s delay0.50.51.5-0.3-0.10.2-1.1-0.3-1.10.21.10.8-0.8-0.30.3-1.2-1.2-0.10.3-0.3
Delay disc. indifference point, 4s delay0.10.10.4-0.1-0.20.3-0.4-0.1-0.30.20.1-0.1-0.1-0.30.7-0.6-0.60.1-0.10.1
Delay disc. indifference point, 8s delay0.10.10.50.00.10.5-0.2-0.4-0.20.30.30.1-0.2-0.0-0.0-0.7-0.70.30.00.0
Indifference point function ln k1.22.14.01.31.6-2.01.31.91.4-1.9-1.2-1.21.21.2-1.41.51.51.3-1.31.3
Indifference point function log k1.22.14.01.31.6-2.01.31.91.4-1.9-1.2-1.21.21.2-1.41.51.51.3-1.31.3
Patch foraging total patch changes 0 sec0.40.73.11.81.6-0.20.2-0.30.30.2-0.2-0.40.4-0.1-1.61.11.11.1-0.20.2
Patch foraging total patch changes 12 sec0.50.71.6-0.2-0.11.0-1.0-1.3-1.01.10.90.8-0.7-1.0-0.4-0.8-0.8-0.30.7-0.6
Patch foraging total patch changes 18 sec1.21.95.2-0.6-1.02.1-1.1-2.3-1.22.11.11.1-1.2-2.00.5-0.8-0.8-1.01.3-1.2
Patch foraging total patch changes 24 sec0.10.10.60.40.30.5-0.0-0.60.10.4-0.1-0.30.5-0.0-0.80.50.50.4-0.10.1
Patch foraging total patch changes 6 sec0.71.02.50.10.01.3-1.2-1.6-1.31.51.21.0-1.1-1.3-0.0-0.6-0.6-0.20.8-0.8
Patch foraging time to switch 0 sec1.02.13.5-1.4-1.71.3-1.6-1.3-1.61.21.41.4-1.4-1.31.2-1.9-1.9-1.41.1-1.1
Patch foraging water rate 0 sec0.51.01.81.31.3-0.70.90.81.1-0.6-0.8-1.00.90.8-0.61.41.41.3-0.90.9
Patch foraging water rate 12 sec1.02.23.31.81.4-1.71.51.81.4-1.4-1.3-1.51.71.8-0.41.61.61.4-1.21.2
Patch foraging water rate 18 sec0.50.71.20.80.3-0.90.81.10.8-1.0-0.7-0.90.90.90.90.50.50.9-0.90.9
Patch foraging water rate 24 sec2.23.04.81.61.3-2.01.72.21.8-2.1-1.5-1.82.01.9-0.21.61.61.8-1.71.7
Patch foraging water rate 6 sec1.42.02.91.51.7-1.61.41.71.4-1.3-1.2-1.31.31.3-1.31.51.51.4-1.11.1
Seeking ratio, delayed vs. immediate footshock1.82.23.9-1.7-1.40.8-1.6-0.7-1.71.21.91.9-2.0-1.21.7-1.6-1.6-1.21.0-1.0
Distance traveled before self-admin0.20.30.70.20.30.0-0.6-0.6-0.70.70.80.7-0.7-0.5-0.3-0.7-0.7-0.20.6-0.6
Distance traveled after self-admin0.10.10.70.70.7-0.4-0.10.3-0.10.10.20.1-0.10.1-0.80.10.10.10.3-0.3
Extensor digitorum longus weight0.10.20.9-0.20.30.4-0.4-0.9-0.30.90.50.4-0.8-0.9-0.30.00.00.20.1-0.1
Bone: elastic displacement0.10.10.4-0.2-0.3-0.3-0.00.3-0.1-0.40.1-0.00.30.60.5-0.4-0.40.0-0.30.3
Bone: elastic work1.21.63.11.81.5-1.21.31.21.3-1.2-1.3-1.31.51.5-1.20.90.91.2-0.80.8
Bone: endosteal estimation0.00.10.60.80.3-0.1-0.2-0.0-0.10.00.10.0-0.0-0.2-0.0-0.0-0.00.10.2-0.2
Bone: endosteal perimeter0.51.03.01.71.5-1.00.90.60.9-0.6-0.9-0.90.90.6-1.51.21.20.7-0.20.2
Epididymis fat weight0.72.39.63.11.6-1.71.51.71.2-1.8-1.5-1.61.41.80.31.31.30.8-0.10.0
Delta time in closed arm before/after self-admin0.10.10.7-0.0-0.00.4-0.0-0.50.00.70.20.1-0.5-0.80.0-0.3-0.30.3-0.10.1
Delta time in open arm before/after self-admin0.30.31.5-0.1-0.80.5-0.5-0.3-0.50.10.30.4-0.2-0.21.2-0.4-0.4-0.80.6-0.6
Diff in mean of infusions in LGA sessions1.31.52.80.4-0.21.3-1.4-1.2-1.61.11.31.3-1.3-1.30.7-1.3-1.3-1.11.7-1.7
Delay discount exponential model param0.10.10.2-0.0-0.1-0.20.1-0.10.10.1-0.00.1-0.1-0.2-0.10.50.5-0.50.3-0.4
Extinction: sum of active levers before priming0.10.11.30.3-0.60.30.20.10.1-0.6-0.1-0.20.40.21.10.10.1-0.10.1-0.1
Active lever presses in extinction session 60.60.61.1-0.5-0.70.7-0.8-0.7-1.00.60.70.8-0.6-0.70.7-1.0-1.0-0.80.7-0.7
Bone: final force4.36.916.04.03.4-2.22.82.02.9-1.9-2.8-2.82.62.3-2.72.72.72.7-1.61.6
Bone: final moment4.36.815.43.93.3-2.32.82.02.9-1.9-2.8-2.82.62.2-2.82.62.62.6-1.61.6
Food consumed during 24 hour testing period0.10.11.00.1-0.40.00.3-0.20.20.1-0.1-0.20.40.01.00.20.20.2-0.40.4
Glucose0.10.21.71.30.70.30.2-0.20.30.4-0.3-0.20.2-0.0-0.30.40.40.10.6-0.6
Heart weight2.13.24.80.72.0-2.21.82.01.6-1.9-1.8-1.71.51.7-2.21.31.31.9-2.12.0
Delay discount hyperbolic model param0.10.10.30.1-0.0-0.30.20.00.20.0-0.00.1-0.0-0.1-0.10.60.6-0.50.4-0.4
Intermittent access intake day 1-15 change1.12.34.41.21.2-1.51.61.91.6-2.0-1.7-1.62.12.1-1.01.51.50.9-0.90.9
Intermittent access intake escalation1.22.55.51.01.0-1.61.71.91.7-2.1-1.8-1.72.12.3-0.91.51.50.9-1.01.0
Intermittent access intake escalation 21.21.43.61.41.1-1.41.11.71.1-1.9-1.2-1.21.51.5-0.40.90.90.6-0.40.4
Intermitt. access day 1 inactive lever presses0.00.20.60.20.5-0.60.20.60.3-0.7-0.3-0.1-0.20.5-0.8-0.2-0.2-0.30.3-0.3
Intermitt. access day 15 inactive lever presses0.10.10.9-0.50.2-0.4-0.00.3-0.0-0.3-0.00.1-0.2-0.0-0.9-0.3-0.3-0.20.0-0.1
Intermitt. access escalation Index0.10.10.8-0.9-0.60.2-0.4-0.2-0.40.10.40.2-0.3-0.20.3-0.3-0.30.1-0.40.4
Intermittent access day 1 total infusions0.20.30.90.10.50.3-0.5-0.5-0.50.60.50.5-0.8-0.4-0.9-0.3-0.3-0.10.5-0.5
Intermittent access day 15 total infusions1.21.73.81.01.2-1.41.31.61.3-1.7-1.4-1.31.41.9-1.21.31.30.9-0.80.8
Intermittent access terminal intake (last 3 days)0.81.11.41.01.0-1.01.11.21.0-1.1-1.1-1.11.21.2-0.91.11.10.8-0.60.6
Intermittent access total infusions0.60.71.51.21.2-0.70.90.70.8-0.6-0.8-0.80.70.6-1.21.01.00.6-0.20.2
Intermittent access day 1 locomotion0.20.21.11.11.0-0.10.3-0.10.30.1-0.1-0.1-0.00.3-0.80.40.40.20.4-0.4
Intermittent access day 15 total locomotion0.40.71.20.90.9-0.61.10.71.1-0.8-1.0-0.90.90.6-0.71.11.10.7-0.40.4
Intermittent access total locomotion0.60.72.01.41.3-0.70.90.70.9-0.7-0.8-0.70.70.7-1.11.01.00.6-0.10.0
Intermittent access standard deviation0.20.41.50.50.7-1.00.21.20.2-1.2-0.3-0.30.50.7-0.50.30.30.3-0.20.2
Left kidney weight0.10.41.21.10.40.5-0.1-0.9-0.20.90.20.2-0.5-1.0-0.00.30.3-0.20.9-0.9
Right kidney weight0.20.86.82.61.3-0.30.60.10.5-0.1-0.5-0.50.2-0.1-0.10.80.8-0.01.2-1.2
Cocaine induced anxiety0.91.22.90.20.11.2-1.1-1.5-1.11.71.01.1-1.1-1.3-0.4-1.2-1.2-0.91.3-1.3
Post-drug Anxiety1.11.12.0-0.4-0.51.1-1.1-1.2-1.21.41.11.1-1.2-1.00.4-1.4-1.4-0.91.0-1.0
Baseline Anxiety0.30.31.9-1.1-1.10.1-0.20.2-0.2-0.40.20.2-0.30.01.4-0.0-0.0-0.1-0.40.5
Tail length0.31.33.01.71.6-1.51.01.30.9-1.3-1.0-1.00.61.3-1.01.01.01.1-0.40.4
Length with tail1.35.610.43.23.0-2.42.72.12.5-2.2-2.6-2.62.22.2-2.22.32.32.3-1.31.3
Length without tail2.58.011.43.02.9-2.43.32.33.3-2.4-3.4-3.23.02.4-2.53.33.32.6-2.12.0
Times rat made contact with spout0.10.10.3-0.0-0.20.00.40.00.30.0-0.3-0.30.0-0.20.5-0.1-0.10.5-0.50.6
Lifetime Intake1.01.23.31.51.7-1.11.01.11.0-0.9-1.0-1.00.81.0-1.81.11.11.0-0.40.4
Liver weight, left0.10.21.60.0-0.70.40.3-0.30.10.3-0.1-0.10.0-0.01.3-0.1-0.1-0.60.5-0.5
Liver weight, right0.61.15.72.41.2-0.81.10.80.9-1.0-1.2-1.10.90.90.31.21.20.20.5-0.6
Locomotor activity0.60.91.81.00.4-0.81.31.01.0-0.8-1.0-1.11.10.70.60.90.91.0-1.01.0
Locomotor testing distance0.40.81.50.40.2-1.11.01.20.8-1.2-0.7-0.81.00.80.50.50.50.9-1.21.2
Locomotor testing rearing0.10.21.50.2-0.4-0.2-0.00.5-0.1-0.60.2-0.00.30.31.2-0.3-0.30.1-0.30.3
Locomotion in novel chamber0.40.50.90.90.4-0.70.80.80.7-1.0-0.6-0.80.90.70.30.60.60.8-0.60.6
Locomotion in novel chamber post-restriction3.86.29.41.91.4-2.52.62.82.6-2.8-2.8-3.03.12.9-0.62.62.62.3-2.32.3
Fecal boli incidents, locomotor time 10.00.10.40.3-0.20.10.20.20.3-0.0-0.2-0.20.4-0.10.60.10.10.00.1-0.1
Change in fecal boli incidents, locomotor task2.32.33.6-1.6-1.11.6-1.7-1.8-1.61.91.61.6-1.9-1.80.6-1.5-1.5-1.10.9-0.9
Time >=10cm from walls, locomotor time 10.60.61.3-0.2-0.61.1-0.5-1.1-0.31.00.50.6-0.7-1.10.8-0.3-0.3-0.81.1-1.1
Bouts of movement, locomotor time 10.20.31.4-0.0-0.60.4-0.3-0.1-0.40.30.30.3-0.4-0.21.2-0.7-0.7-0.60.7-0.7
Total resting periods, locomotor time 10.40.41.9-0.2-0.80.4-0.5-0.1-0.70.30.40.4-0.4-0.31.4-0.8-0.8-0.60.6-0.6
Rest time, locomotor task time 10.40.51.5-0.8-0.30.2-0.8-0.0-1.10.50.80.6-0.7-0.50.0-1.2-1.2-0.10.0-0.0
Distance moved, locomotor task time 10.10.20.4-0.3-0.40.6-0.4-0.6-0.20.30.50.6-0.5-0.60.2-0.1-0.1-0.60.6-0.6
Vertical activity count, locomotor time 10.00.10.40.3-0.0-0.20.20.20.4-0.2-0.2-0.10.20.10.60.50.5-0.20.1-0.1
Time >=10cm from walls, locomotor time 20.10.11.2-1.1-0.70.1-0.20.00.2-0.00.20.2-0.0-0.10.30.10.1-0.2-0.30.3
Bouts of movement, locomotor time 20.10.20.5-0.7-0.50.6-0.5-0.6-0.50.60.60.6-0.6-0.40.1-0.3-0.3-0.30.3-0.2
Total resting periods, locomotor time 20.10.20.5-0.6-0.40.7-0.5-0.7-0.50.70.50.5-0.6-0.5-0.2-0.3-0.3-0.30.3-0.3
Rest time, locomotor task time 20.10.10.50.20.50.20.0-0.1-0.30.20.10.0-0.2-0.0-0.7-0.5-0.50.4-0.00.0
Distance moved, locomotor task time 20.10.10.3-0.3-0.2-0.20.10.20.3-0.3-0.00.10.2-0.00.10.50.5-0.50.2-0.2
Vertical activity count, locomotor time 20.40.51.0-0.20.2-0.80.70.81.0-0.8-0.7-0.50.80.6-0.40.90.90.2-0.70.7
Light reinforcement 10.20.41.30.2-0.30.7-0.6-1.0-0.71.00.60.6-0.7-1.10.8-0.2-0.2-0.40.6-0.6
Light reinforcement 20.81.33.5-0.2-0.51.7-1.1-1.8-1.11.91.01.0-1.2-1.60.3-0.7-0.7-0.81.1-1.1
Bone: marrow area0.00.00.50.70.2-0.1-0.2-0.0-0.20.00.10.0-0.0-0.20.0-0.0-0.00.20.1-0.1
Bone: maximum diameter2.24.06.62.62.4-1.82.11.72.1-1.6-2.0-2.02.01.8-2.52.42.41.8-1.21.2
Bone: maximum force4.78.318.44.33.5-2.53.12.33.2-2.2-3.2-3.23.02.6-2.52.92.92.8-1.81.7
Bone: maximum moment4.47.716.54.13.3-2.53.02.23.1-2.2-3.1-3.12.92.4-2.52.82.82.7-1.71.7
Mean time between licks in bursts0.51.23.41.91.7-1.30.71.30.6-1.3-0.9-0.91.01.1-1.01.01.01.1-0.50.5
Mean num. licks in bursts0.50.81.61.00.6-0.61.30.51.3-0.5-1.2-1.11.21.1-0.31.01.00.3-0.30.3
Cd content in liver7.88.612.22.12.7-2.93.33.03.3-2.9-3.3-3.33.33.5-2.42.72.72.8-2.82.7
Co content in liver0.00.10.2-0.20.00.3-0.0-0.10.00.2-0.0-0.10.30.2-0.2-0.5-0.50.1-0.20.2
Cu content in liver0.10.20.9-0.9-0.70.3-0.0-0.0-0.00.00.10.0-0.0-0.20.40.10.10.2-0.70.7
Fe content in liver0.40.51.0-1.0-1.00.8-0.6-0.7-0.60.70.60.7-0.9-0.90.8-0.1-0.1-0.90.7-0.7
K content in liver1.71.73.4-1.9-1.51.5-1.6-1.3-1.51.31.71.5-1.3-1.30.9-0.8-0.8-0.90.4-0.4
Mg content in liver0.10.10.3-0.5-0.20.2-0.3-0.1-0.20.10.30.3-0.2-0.1-0.3-0.1-0.1-0.2-0.10.1
Mn content in liver0.10.10.6-0.30.2-0.5-0.10.5-0.1-0.30.20.2-0.00.3-0.8-0.2-0.2-0.20.0-0.1
Na content in liver1.71.94.4-1.5-1.91.2-1.6-0.9-1.51.01.61.5-1.2-1.22.1-1.1-1.1-1.30.9-0.9
Rb content in liver2.63.06.60.91.9-1.61.51.41.6-1.5-1.6-1.51.31.2-2.62.52.51.6-1.61.6
Se content in liver0.00.10.2-0.5-0.50.1-0.10.4-0.1-0.10.10.10.00.10.00.30.3-0.40.1-0.1
Sr content in liver0.30.31.00.3-0.4-0.0-0.30.7-0.3-0.40.20.1-0.10.61.0-0.4-0.4-0.70.8-0.8
Zn content in liver0.20.20.6-0.1-0.40.7-0.5-0.4-0.60.40.50.5-0.1-0.10.3-0.4-0.4-0.70.8-0.8
Bone: minimum diameter1.32.38.52.91.9-1.51.71.41.7-1.4-1.6-1.61.61.4-0.81.51.51.0-0.20.2
Time in familiar zone, hab. session 10.20.20.50.70.3-0.40.20.50.2-0.4-0.1-0.20.20.50.50.50.5-0.00.3-0.3
Time in novel zone, hab. session 10.60.62.1-0.30.5-0.80.60.70.5-0.7-0.5-0.50.60.5-0.80.20.21.1-1.41.5
Total zone transitions, hab. session 10.20.22.0-0.1-0.70.5-0.5-0.2-0.30.00.40.3-0.3-0.31.4-0.5-0.5-0.20.2-0.2
Total locomotion distance, hab. session 10.20.22.10.1-0.8-0.1-0.20.4-0.1-0.50.1-0.10.10.11.5-0.5-0.50.1-0.30.3
Locomotion velocity, hab. session 10.30.52.9-0.1-1.10.4-0.8-0.2-0.60.10.60.5-0.4-0.51.7-0.9-0.9-0.40.3-0.3
Time in familiar zone, hab. session 20.10.10.60.20.2-0.4-0.1-0.0-0.10.00.20.3-0.1-0.10.40.80.8-0.30.3-0.3
Time in novel zone, hab. session 20.30.30.60.30.3-0.30.70.80.7-0.7-0.7-0.70.60.7-0.5-0.1-0.10.6-0.70.7
Total zone transitions, hab. session 20.00.00.1-0.3-0.20.20.2-0.00.2-0.0-0.10.0-0.0-0.20.30.00.0-0.20.1-0.1
Total locomotion distance, hab. session 20.40.61.2-0.00.2-0.90.80.90.9-1.1-0.8-0.80.80.7-0.00.60.60.6-1.01.0
Locomotion velocity, hab. session 20.20.30.7-0.2-0.1-0.60.50.70.6-0.8-0.5-0.50.50.50.30.20.20.4-0.70.7
Novel to familiar place preference ratio0.30.31.11.00.6-0.30.80.50.9-0.4-0.8-0.80.50.5-0.10.40.40.4-0.10.1
Novelty place preference0.20.20.60.80.4-0.10.60.30.7-0.2-0.6-0.60.40.3-0.10.20.20.3-0.10.1
Time in novel zone, NPP test0.10.10.40.60.2-0.00.50.20.6-0.1-0.5-0.50.20.10.20.10.10.2-0.10.1
Total zone transitions, NPP test0.10.21.1-0.7-0.80.4-0.2-0.2-0.2-0.00.10.0-0.1-0.21.1-0.4-0.40.1-0.40.4
Total locomotion distance, NPP test0.30.31.0-0.7-0.8-0.3-0.10.2-0.0-0.4-0.1-0.20.10.11.0-0.8-0.80.4-1.01.0
Locomotion velocity, NPP test0.30.41.5-0.8-1.0-0.0-0.5-0.0-0.4-0.10.1-0.0-0.1-0.11.0-1.2-1.20.2-0.60.6
Intraocular pressure0.91.35.00.81.6-1.31.01.01.0-1.0-1.1-1.01.00.7-2.20.70.71.1-0.90.9
Delta distance traveled before/after self-admin0.30.31.31.10.7-0.30.50.80.5-0.5-0.5-0.50.40.2-0.30.50.50.20.2-0.2
Delta ambulatory time before/after self-admin0.10.10.40.60.40.10.40.40.5-0.1-0.5-0.40.30.0-0.30.50.50.00.1-0.1
Parametrial fat weight0.40.95.62.41.9-0.80.60.50.5-0.4-0.6-0.60.30.3-1.30.70.70.50.5-0.6
Pavlov. Cond. lever latency0.10.10.3-0.40.1-0.4-0.10.2-0.10.10.20.4-0.1-0.0-0.2-0.2-0.2-0.60.4-0.4
Pavlov. Cond. magazine entry latency0.10.10.70.80.3-0.30.20.30.3-0.3-0.3-0.40.40.40.20.10.10.5-0.30.3
Pavlov. Cond. change in total contacts0.40.41.60.80.7-0.10.50.20.5-0.3-0.5-0.70.50.4-0.70.30.31.3-0.91.0
Pavlov. Cond. index score0.10.10.40.4-0.30.4-0.2-0.2-0.20.20.1-0.1-0.0-0.10.6-0.4-0.40.3-0.10.2
Pavlov. Cond. latency score0.20.20.60.0-0.50.7-0.4-0.5-0.50.40.40.1-0.3-0.40.6-0.7-0.70.2-0.10.1
Pavlov. Cond. lever contacts0.10.10.30.5-0.10.5-0.1-0.4-0.10.2-0.0-0.2-0.1-0.20.3-0.3-0.30.3-0.00.1
Pavlov. Cond. magazine entry number0.10.10.7-0.9-0.30.2-0.1-0.2-0.10.20.10.3-0.3-0.3-0.30.10.1-0.30.1-0.1
Pavlov. Cond. intertrial magazine entries2.22.65.3-0.11.1-1.81.51.51.5-1.7-1.5-1.51.61.6-1.81.41.41.8-2.32.3
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.3-0.30.5-0.3-0.3-0.30.20.20.1-0.2-0.20.5-0.4-0.40.2-0.00.0
Pavlov. Cond. response bias0.20.20.80.90.3-0.20.40.30.4-0.3-0.4-0.50.40.40.20.30.30.7-0.50.5
Pavlov. Cond. lever latency0.81.12.3-0.00.3-1.31.11.51.0-1.5-1.0-1.01.01.2-0.50.60.60.9-1.41.4
Pavlov. Cond. magazine entry latency0.20.30.80.2-0.00.9-0.4-0.7-0.40.80.20.2-0.4-0.50.30.10.1-0.40.9-0.9
Pavlov. Cond. change in total contacts0.61.02.8-0.2-0.21.5-1.1-1.5-1.11.71.00.9-0.9-1.10.3-0.6-0.6-0.71.1-1.0
Pavlov. Cond. index score0.60.82.20.0-0.11.4-1.0-1.4-0.91.50.80.8-0.9-1.00.2-0.3-0.3-0.71.2-1.2
Pavlov. Cond. latency score0.70.92.2-0.2-0.31.5-1.1-1.4-1.01.50.80.8-0.9-1.00.4-0.4-0.4-0.81.2-1.2
Pavlov. Cond. lever contacts1.01.32.9-0.3-0.41.5-1.2-1.7-1.11.71.11.1-1.2-1.30.5-0.7-0.7-1.01.4-1.4
Pavlov. Cond. magazine entry number0.30.41.2-0.6-0.3-1.00.41.00.4-1.0-0.2-0.20.40.5-0.2-0.1-0.10.4-1.11.1
Pavlov. Cond. intertrial magazine entries0.10.10.6-0.4-0.5-0.40.10.50.0-0.40.20.2-0.00.10.8-0.2-0.2-0.1-0.20.2
Pavlov. Cond. lever-magazine prob. diff.0.50.71.80.1-0.01.3-0.9-1.3-0.81.40.70.7-0.8-0.90.2-0.3-0.3-0.61.2-1.1
Pavlov. Cond. response bias0.71.02.10.2-0.11.3-0.9-1.4-0.81.40.80.9-1.0-1.10.4-0.4-0.4-0.81.4-1.4
Time in closed arm before self-admin0.70.94.90.71.3-0.1-1.0-0.2-1.00.40.90.9-0.9-0.4-2.2-0.6-0.6-0.20.9-0.9
Time in closed arm after self-admin0.50.55.50.81.5-0.5-0.20.3-0.2-0.10.30.2-0.4-0.1-2.3-0.1-0.10.40.1-0.1
Time in open arm before self-admin0.30.32.7-0.3-0.5-0.10.50.30.6-0.2-0.5-0.50.30.11.60.30.30.2-0.40.4
Time in open arm after self-admin0.60.62.6-0.2-0.7-0.60.60.90.6-0.9-0.8-0.71.01.01.60.60.60.1-0.60.6
Bone: periosteal estimation1.63.48.32.92.2-1.91.91.62.0-1.6-2.0-2.01.91.6-1.61.91.91.6-0.90.9
Bone: periosteal perimeter3.25.410.93.33.0-2.32.51.82.5-1.8-2.4-2.32.42.1-2.92.52.51.9-1.11.1
Bone: post-yield work0.40.61.20.70.4-0.51.00.60.9-0.6-1.1-1.10.80.4-0.10.90.90.8-0.80.8
Progressive ratio test 1 active lever presses0.20.31.61.01.1-0.00.1-0.20.10.3-0.1-0.2-0.1-0.1-1.30.20.20.50.1-0.1
Progressive ratio test 1 breakpoint0.20.21.60.91.0-0.10.1-0.10.10.3-0.1-0.2-0.1-0.0-1.30.20.20.50.1-0.1
Progressive ratio test 1 inactive lever presses0.30.41.41.01.1-1.00.30.90.3-1.0-0.2-0.20.00.6-1.20.30.30.10.3-0.3
Progressive ratio test 2 active lever presses0.20.31.00.80.9-0.30.50.30.5-0.2-0.4-0.40.50.5-1.00.60.60.5-0.00.0
Progressive ratio test 2 breakpoint0.20.20.70.70.8-0.20.40.30.4-0.1-0.3-0.40.40.5-0.80.50.50.4-0.00.0
Progressive ratio test 2 inactive lever presses0.71.14.51.01.5-1.00.90.90.9-0.9-0.9-0.90.70.6-2.10.90.91.1-0.80.8
Incentive Sensitization - Responses0.10.10.20.30.3-0.10.20.10.3-0.1-0.2-0.30.40.5-0.30.30.30.3-0.20.2
Incentive Sensitization - Breakpoint0.00.00.20.30.10.00.20.10.2-0.0-0.2-0.20.30.4-0.00.20.20.2-0.10.1
Sum of active levers in priming session hrs 5-61.31.22.4-0.3-0.5-0.71.31.11.1-1.5-1.3-1.31.61.10.41.11.10.6-1.31.3
Progressive ratio0.10.20.50.30.2-0.20.50.20.5-0.5-0.6-0.50.70.6-0.50.50.50.2-0.40.4
Food seeking constrained by brief footshock3.34.16.80.61.1-2.02.12.12.1-2.1-2.2-2.22.62.2-1.62.02.01.8-2.32.3
Seeking ratio, punishment vs. effort0.71.02.10.00.4-1.30.81.40.9-1.1-0.9-1.01.01.0-0.00.80.81.0-1.31.3
Retroperitoneal fat weight1.45.814.53.83.3-2.82.22.72.1-2.5-2.3-2.42.22.3-2.02.22.22.3-1.21.2
Reaction time number correct0.20.41.71.0-0.1-0.90.01.30.2-1.0-0.1-0.20.80.81.1-0.0-0.0-0.10.1-0.1
Reaction time mean minus median0.40.92.4-0.7-0.71.3-0.9-1.5-1.11.40.60.7-1.1-1.30.8-0.5-0.5-0.70.9-0.9
Reaction time mean minus median AUC0.30.71.8-0.8-0.41.1-1.0-1.4-1.01.30.60.6-1.1-1.10.1-0.4-0.4-0.60.8-0.8
Reaction time num false alarms0.20.21.40.80.70.30.3-0.20.20.3-0.4-0.30.6-0.2-1.20.50.50.20.1-0.1
Reaction time num false alarms AUC0.20.21.40.60.50.60.3-0.40.20.5-0.3-0.30.5-0.3-1.20.50.50.10.1-0.1
Reaction time trials correct on left0.20.41.71.0-0.1-0.90.01.30.2-1.0-0.1-0.20.80.81.1-0.0-0.0-0.10.1-0.1
Reaction time trials on left0.20.41.61.1-0.1-0.80.01.30.3-0.9-0.1-0.20.80.81.10.00.0-0.10.2-0.2
Reaction time mean0.20.31.00.30.40.5-0.2-0.8-0.30.60.00.2-0.5-0.5-0.30.10.1-0.51.0-1.0
Reaction time mean AUC0.71.12.3-0.3-0.31.2-0.9-1.5-1.01.30.70.9-1.2-1.10.2-0.6-0.6-1.11.5-1.5
Median of all reaction times0.10.20.60.50.60.20.1-0.40.10.2-0.20.0-0.2-0.1-0.70.40.4-0.40.8-0.8
Reaction time omissions0.40.51.50.80.31.1-0.3-1.1-0.31.10.20.2-0.6-0.6-0.10.00.0-0.41.2-1.2
Reaction time false alarm rate0.30.52.80.30.90.40.7-0.50.60.4-0.7-0.60.4-0.1-1.70.80.80.7-0.40.4
Reaction time premature initiation rate0.10.10.3-0.5-0.40.20.2-0.50.10.4-0.2-0.3-0.0-0.30.4-0.2-0.20.4-0.50.5
Reaction time premature initiations0.00.10.60.1-0.4-0.20.00.10.00.00.0-0.20.20.00.8-0.3-0.30.1-0.20.2
Std. dev. reaction times0.20.41.40.10.10.8-0.2-1.2-0.41.00.00.2-0.7-0.70.30.10.1-0.51.0-1.0
Reaction time trials completed0.20.41.61.1-0.1-0.80.01.30.3-0.9-0.1-0.20.80.81.10.00.0-0.10.2-0.2
Reaction time trials AUC0.30.52.01.30.1-1.00.21.40.4-1.1-0.2-0.30.91.00.90.10.1-0.00.1-0.1
Run reversals in cocaine runway, females1.81.85.21.71.9-1.31.21.11.3-1.2-1.1-1.11.21.3-2.31.41.41.2-0.50.5
Run reversals in cocaine runway, males1.11.11.9-1.0-1.31.3-0.9-1.2-1.01.30.81.0-1.1-1.41.1-0.9-0.9-1.00.7-0.7
Latency to leave start box in cocaine runway0.00.00.20.10.1-0.30.10.30.1-0.40.20.1-0.20.20.20.10.10.10.0-0.0
Latency to leave start box in cocaine runway, F0.40.50.80.60.7-0.90.80.90.8-0.9-0.5-0.60.50.8-0.50.80.80.8-0.50.5
Latency to leave start box in cocaine runway, M0.90.91.2-0.8-0.80.9-1.0-0.9-1.10.71.01.0-1.0-0.91.0-1.1-1.1-0.90.8-0.8
Std. dev. time between licks in bursts1.41.93.81.91.8-1.51.21.31.1-1.3-1.3-1.41.61.6-1.10.90.91.5-1.11.1
Total sessions with >9 infusions1.61.95.61.82.1-1.51.21.31.2-1.2-1.1-1.11.01.6-2.41.21.21.1-0.40.4
Short access day 1 total inactive lever presses1.82.45.51.11.9-2.31.32.11.3-2.2-1.1-1.10.91.2-2.31.31.31.3-1.11.1
Short access day 10 total inactive lever presses1.84.47.7-1.9-1.51.9-2.3-1.9-2.31.82.42.5-2.8-2.00.4-2.6-2.6-1.91.7-1.7
Short access day 1 total infusions3.44.57.42.42.6-2.72.02.62.0-2.4-2.0-2.01.82.3-2.51.81.82.0-1.31.3
Short access day 10 total infusions1.31.73.10.91.5-1.81.01.71.0-1.5-1.0-1.11.01.4-1.61.21.21.4-1.21.1
Short access total infusions1.01.33.61.51.7-1.40.91.20.9-1.1-0.9-0.90.71.0-1.91.01.01.2-0.60.6
Short access day 1 locomotion3.34.09.12.22.8-2.61.72.41.7-2.3-1.6-1.71.52.3-3.01.61.61.7-1.01.0
Short access day 10 total locomotion2.03.66.61.92.0-2.42.02.32.0-2.3-1.7-1.71.72.6-1.52.02.01.5-1.21.2
Short access total locomotion2.73.34.81.92.2-2.11.91.82.0-1.7-1.6-1.71.72.0-2.11.91.91.6-1.21.1
One hour access (0.3 mA shock)2.02.34.10.81.4-1.41.31.51.3-1.7-1.3-1.41.41.5-2.01.61.61.7-1.61.6
Compulsive drug intake0.20.31.0-1.0-0.80.7-0.3-0.9-0.30.60.40.4-0.5-0.20.2-0.3-0.3-0.1-0.20.2
One hour access (shock baseline)1.21.93.71.61.8-1.51.21.51.2-1.5-1.2-1.21.41.5-1.91.31.31.2-0.70.7
Social response proportion7.28.29.82.52.7-2.83.12.73.0-2.6-3.1-3.13.13.1-2.92.72.72.9-2.82.8
Social responses3.44.46.11.51.5-2.22.22.22.1-2.2-2.2-2.32.32.5-1.22.02.02.2-2.32.3
Social time0.40.61.7-0.40.5-0.40.80.50.7-0.4-0.7-0.60.40.6-1.31.01.00.8-1.11.1
Soleus weight0.10.31.51.21.1-0.20.10.1-0.0-0.2-0.1-0.30.1-0.1-0.90.50.50.70.00.0
Bone: stiffness2.43.98.93.02.7-1.62.11.42.2-1.3-2.1-2.11.91.4-2.22.12.11.9-1.11.0
Tibialis anterior weight0.10.20.50.70.4-0.50.60.20.6-0.3-0.5-0.50.20.10.40.40.40.5-0.30.3
Time to tail flick, vehicle, before self-admin0.50.51.00.90.6-0.40.80.60.8-0.8-0.9-0.80.90.8-0.21.01.00.5-0.40.4
Time to tail flick, vehicle, after self-admin0.50.61.4-0.1-0.40.1-0.8-0.2-0.90.40.91.0-0.8-0.70.7-1.0-1.0-1.11.2-1.2
Time to tail flick, test, before self-admin0.91.04.20.81.4-0.91.00.70.9-0.8-0.9-0.90.90.9-2.00.70.70.9-0.60.6
Time to tail flick, test, after self-admin0.10.10.3-0.5-0.30.40.4-0.10.30.3-0.4-0.40.50.2-0.10.40.40.0-0.20.2
Delta time to tail flick, vehicle, before/after SA1.00.91.8-1.1-0.80.1-1.0-0.5-1.00.81.21.2-1.2-1.00.6-1.3-1.3-0.90.7-0.7
Delta time to tail flick, test, before/after SA0.20.21.5-0.1-0.60.10.10.10.20.1-0.2-0.20.40.31.20.40.4-0.1-0.10.1
Tibia length0.51.32.81.21.3-0.91.00.71.1-0.7-1.1-1.10.60.5-1.41.71.71.3-1.01.0
Ambulatory time before self-admin0.50.81.60.20.20.2-1.0-0.8-1.20.81.31.1-1.1-0.7-0.1-1.1-1.1-0.51.0-0.9
Ambulatory time after self-admin0.20.21.21.10.8-0.20.00.0-0.00.20.20.1-0.10.0-0.7-0.1-0.10.10.5-0.5
Bone: tissue strength0.90.92.00.2-0.50.9-0.7-1.2-0.71.20.70.8-0.8-0.90.5-1.2-1.2-1.11.4-1.4
Total heroin consumption0.50.61.90.3-0.31.4-0.5-1.1-0.70.80.50.5-0.6-1.10.2-0.7-0.7-0.61.0-1.0
Bone: trabecular number4.67.710.72.72.3-3.22.93.12.9-3.3-2.9-3.03.13.2-0.62.82.82.5-2.42.4
Bone: trabecular spacing1.01.42.3-0.8-0.91.5-1.3-1.3-1.21.41.31.3-1.3-1.20.2-0.9-0.9-1.11.2-1.2
Bone: trabecular thickness3.44.26.21.91.7-2.12.42.02.2-2.1-2.5-2.52.42.1-0.51.81.82.1-2.02.0
Bone: trabecular tissue density0.60.92.40.0-1.11.1-0.7-1.1-0.61.00.60.6-0.6-0.71.6-1.0-1.0-1.01.1-1.1
Water consumed over 24 hours0.50.61.21.00.3-0.41.00.50.9-0.5-1.0-1.10.90.80.40.40.41.0-0.90.9
Number of responses in last shaping day2.62.93.71.01.4-1.91.71.91.7-1.9-1.7-1.81.61.8-1.61.81.81.9-1.71.7