Hub : Genes

Hibch

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain mRNA stability Hibch 0.76 0.06 0.0e+00 0.33 0.36 0.36 0.36 3.3e-31 3.4e-35 8.9e-35 2.2e-34
2 Liver isoform ratio NM_001013112.2 0.2 0.12 4.9e-11 0.03 0.04 0.04 0.04 9.9e-05 1.2e-05 1.0e-05 2.7e-05
3 NAcc mRNA stability Hibch 0.18 0.08 0.0e+00 0.11 0.12 0.11 0.11 5.5e-16 5.6e-17 1.8e-16 9.3e-17
4 IL gene expression Hibch 0.35 0.24 2.0e-04 0.11 0.11 0.09 0.1 1.3e-03 1.5e-03 4.1e-03 2.9e-03
5 OFC gene expression Hibch 0.33 0.14 6.5e-06 0.21 0.2 0.16 0.18 9.4e-06 2.1e-05 1.6e-04 4.1e-05
6 IC gene expression Hibch 0.12 0.07 4.0e-05 0.13 0.11 0.1 0.12 3.8e-06 1.9e-05 8.3e-05 8.2e-06
7 IC mRNA stability Hibch 0.34 0.12 5.3e-12 0.18 0.24 0.21 0.23 7.4e-08 2.0e-10 2.2e-09 3.0e-10
8 pVTA gene expression Hibch 0.3 0.12 0.0e+00 0.3 0.32 0.34 0.31 2.1e-24 1.3e-26 8.4e-28 3.5e-25
9 LHb gene expression Hibch 0.46 0.16 3.1e-07 0.11 0.17 0.14 0.16 1.2e-03 6.1e-05 3.2e-04 1.1e-04
10 Brain gene expression Hibch 0.27 0.11 0.0e+00 0.32 0.31 0.31 0.31 5.7e-30 4.9e-29 3.3e-29 1.4e-29
11 Brain intron excision ratio chr9_56082804_56086178 0.03 0.02 8.2e-03 0.02 0.02 0.01 0.02 2.4e-03 8.5e-03 3.1e-02 3.3e-03
12 PL gene expression Hibch 0.22 0.12 0.0e+00 0.23 0.22 0.22 0.23 2.1e-24 5.2e-24 3.9e-23 5.1e-25
13 BLA gene expression Hibch 0.1 0.06 1.3e-05 0.07 0.08 0.09 0.08 2.0e-04 3.8e-05 2.5e-05 3.6e-05
14 Adipose intron excision ratio chr9_56082804_56095679 0.08 0.05 1.1e-07 0.02 0.04 0.04 0.04 9.8e-04 2.4e-05 6.9e-05 2.1e-05
15 NAcc gene expression Hibch 0.12 0.06 0.0e+00 0.1 0.1 0.09 0.1 3.0e-14 1.1e-14 7.1e-13 1.5e-14
16 BLA mRNA stability Hibch 0.3 0.13 1.1e-16 0.23 0.25 0.24 0.27 1.0e-12 2.9e-13 4.9e-13 2.0e-14
17 PL mRNA stability Hibch 0.27 0.11 0.0e+00 0.25 0.26 0.26 0.26 1.5e-27 1.2e-28 9.0e-29 1.2e-28
18 RMTg gene expression Hibch 0.13 0.09 6.6e-03 0.02 0.01 -0 0.01 1.1e-01 1.9e-01 3.5e-01 2.1e-01
19 pVTA mRNA stability Hibch 0.08 0.05 8.9e-05 0.02 0.04 0.03 0.03 4.4e-03 7.1e-04 2.3e-03 3.8e-03
20 Liver isoform ratio NM_001398668.1 0.09 0.06 1.2e-07 0.03 0.03 0.03 0.02 1.7e-04 8.4e-04 5.9e-04 9.1e-04
21 OFC mRNA stability Hibch 0.32 0.15 2.3e-05 0.11 0.13 0.13 0.15 1.4e-03 5.5e-04 4.7e-04 2.0e-04
22 IL mRNA stability Hibch 0.41 0.16 3.6e-06 0.19 0.17 0.09 0.18 2.3e-05 5.7e-05 4.5e-03 4.9e-05
23 Adipose gene expression Hibch 0.27 0.1 0.0e+00 0.19 0.21 0.21 0.2 9.8e-21 1.2e-22 2.1e-22 2.5e-22
24 Liver mRNA stability Hibch 0.04 0.03 4.6e-03 -0 -0 -0 0.02 7.2e-01 4.1e-01 5.9e-01 3.0e-03
25 pVTA isoform ratio NM_001013112.2 0.05 0.04 4.9e-03 0.05 0.02 0.04 0.04 1.4e-04 4.4e-03 3.2e-04 5.8e-04
26 Adipose mRNA stability Hibch 0.19 0.08 2.4e-15 0.11 0.11 0.11 0.1 4.4e-12 8.6e-12 7.6e-12 1.4e-11
27 NAcc isoform ratio NM_001013112.2 0.03 0.02 2.8e-03 0.01 0.02 0.02 0.02 4.0e-03 1.2e-03 8.1e-04 9.3e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density2.13.76.12.21.82.1-2.0-1.9-1.92.2-2.2-2.3-1.9-1.8-2.0-1.9-2.5-2.21.72.0-1.62.2-2.22.42.20.0-1.2-0.81.1-1.2
Area under the delay curve0.00.00.10.00.00.10.00.00.00.1-0.20.00.00.0-0.1-0.10.1-0.1-0.00.1-0.20.00.00.30.10.10.4-0.40.40.0
BMI with tail4.013.922.6-4.6-4.5-4.34.74.74.7-4.04.24.24.74.74.44.44.33.6-3.5-3.53.3-2.93.1-3.1-3.12.5-1.4-1.11.1-1.3
BMI without tail0.72.15.5-1.3-1.2-1.41.91.91.9-1.01.31.42.02.11.91.91.50.6-0.5-0.70.5-0.20.00.1-0.12.3-1.2-2.02.0-1.8
Body weight0.00.11.80.00.20.2-0.3-0.2-0.20.1-0.2-0.1-0.1-0.1-0.3-0.40.2-0.00.0-0.1-0.1-0.20.2-0.2-0.3-0.41.30.5-0.40.8
Weight adjusted by age0.71.03.60.80.60.7-1.2-1.2-1.30.3-0.6-0.6-1.2-1.2-1.2-1.2-0.7-0.0-0.30.00.1-0.30.4-0.5-0.6-1.91.01.7-1.81.5
Bone surface0.30.51.30.70.30.7-1.1-1.1-1.10.5-0.7-0.8-1.0-1.0-1.1-1.0-1.1-0.40.10.3-0.10.2-0.10.40.2-1.1-0.00.9-0.60.4
Bone volume1.32.44.71.81.41.8-2.0-2.0-2.01.7-1.8-1.9-1.9-1.9-2.0-1.9-2.2-1.61.21.4-1.11.4-1.31.51.3-0.9-0.30.4-0.1-0.0
Breakpoint value in progressive ratio session1.31.53.41.61.81.5-1.1-1.1-1.11.5-1.5-1.3-1.2-1.2-1.1-1.2-0.7-1.51.31.2-1.41.4-1.41.51.50.21.0-0.60.70.0
Number of licking bursts0.50.93.30.20.30.00.50.50.50.4-0.2-0.10.50.50.50.50.0-0.60.90.8-0.91.0-1.31.21.31.7-1.2-1.81.7-1.6
Context. condit. distance diff. score1.21.56.3-0.4-0.0-0.61.31.31.3-0.20.40.71.41.41.31.31.2-0.20.0-0.20.00.5-0.80.91.02.4-0.7-2.52.5-1.8
Locomotion velocity, session 10.00.10.2-0.00.3-0.00.20.20.20.0-0.00.10.20.20.30.30.3-0.1-0.0-0.10.10.1-0.3-0.00.20.40.5-0.40.4-0.1
Locomotion distance, session 10.30.41.4-0.6-0.3-0.60.50.50.5-0.70.60.70.50.60.60.60.80.7-1.1-1.11.2-0.80.4-0.6-0.5-0.20.80.3-0.20.4
Locomotion velocity, session 21.92.33.6-1.8-1.6-1.71.41.51.5-1.81.71.71.41.51.41.41.61.8-1.9-1.91.9-1.81.5-1.7-1.6-0.20.30.7-0.60.5
Locomotion distance, session 21.01.42.4-1.3-1.2-1.20.90.90.9-1.41.31.30.90.90.90.91.21.5-1.4-1.51.4-1.61.5-1.5-1.6-0.60.81.1-1.11.0
Locomotion velocity, session 30.10.10.3-0.4-0.4-0.40.50.50.5-0.40.40.40.50.60.60.60.40.3-0.3-0.30.2-0.20.1-0.1-0.10.30.1-0.20.2-0.2
Locomotion distance, session 30.30.41.2-0.3-0.4-0.40.60.70.7-0.20.30.30.70.70.70.70.30.00.60.4-0.60.3-0.20.30.31.1-0.9-0.90.9-1.0
Stereotopy head waving bouts, day 30.50.61.3-0.9-0.8-0.90.80.80.8-0.90.80.90.80.80.80.80.90.9-1.1-1.11.1-0.80.7-0.7-0.80.10.20.1-0.10.1
Stereotopy head waving duration, day 30.10.10.5-0.20.0-0.10.20.20.2-0.20.00.20.10.20.10.10.40.1-0.7-0.60.7-0.2-0.00.10.00.00.4-0.20.20.1
Locomotion velocity, session 71.11.13.5-0.7-0.8-0.60.10.10.1-0.90.70.70.10.10.10.10.61.1-1.1-1.11.0-1.41.5-1.4-1.5-1.51.31.8-1.91.7
Locomotion distance, session 70.70.92.6-0.6-0.5-0.50.10.10.1-0.80.70.70.20.20.20.20.71.0-0.7-0.80.6-1.31.5-1.3-1.4-1.21.41.5-1.51.6
Stereotopy head waving bouts, day 70.30.30.60.70.70.7-0.5-0.5-0.50.7-0.7-0.6-0.5-0.5-0.4-0.4-0.5-0.80.70.7-0.70.7-0.70.80.80.3-0.1-0.50.6-0.4
Stereotopy head waving duration, day 70.50.60.91.00.90.9-0.9-0.9-0.91.0-1.0-1.0-0.9-0.9-0.8-0.8-0.9-1.00.70.8-0.70.9-0.80.80.9-0.1-0.2-0.20.3-0.3
Locomotion velocity, session 80.30.41.2-0.3-0.4-0.40.70.70.7-0.30.40.40.60.60.70.70.40.1-0.1-0.10.10.1-0.30.30.41.0-1.0-1.01.1-1.1
Locomotion distance, session 81.01.52.8-1.2-1.0-1.31.61.61.6-1.11.21.41.61.61.71.71.50.9-0.9-1.01.0-0.60.4-0.3-0.31.4-0.4-1.21.2-0.9
Degree of sensitization distance1.01.14.20.00.10.1-0.7-0.7-0.7-0.30.00.0-0.6-0.7-0.7-0.70.10.6-0.8-0.80.8-1.01.1-1.1-1.2-1.91.91.9-1.92.0
Degree of sensitization stereotypy0.40.50.90.70.70.6-0.5-0.5-0.50.8-0.7-0.7-0.4-0.4-0.3-0.3-0.6-0.80.90.9-0.90.9-0.80.90.90.5-0.6-0.70.8-0.7
Conditioned locomotion0.10.11.70.10.40.2-0.1-0.1-0.10.1-0.10.0-0.1-0.1-0.1-0.10.40.00.2-0.0-0.2-0.20.10.1-0.1-0.31.30.2-0.20.7
Cocaine response after cond. corrected0.60.72.9-0.4-0.1-0.3-0.1-0.1-0.1-0.70.40.5-0.1-0.1-0.1-0.10.60.9-0.9-1.11.0-1.21.0-1.0-1.0-1.51.71.5-1.11.4
Cocaine response after cond. not corrected1.21.45.80.30.60.4-1.1-1.1-1.1-0.1-0.3-0.3-1.1-1.0-1.1-1.1-0.20.4-0.6-0.70.7-1.00.9-0.9-0.8-2.42.32.2-1.92.2
Cocaine response before conditioning0.70.82.00.80.70.9-1.2-1.2-1.20.7-0.8-0.9-1.2-1.2-1.2-1.2-1.1-0.50.30.5-0.30.2-0.1-0.10.1-1.30.71.1-1.41.2
Saline control response0.20.20.90.1-0.00.00.20.20.20.2-0.0-0.10.20.20.20.2-0.1-0.30.50.5-0.50.5-0.50.40.40.8-0.9-0.91.0-1.0
Bone: connectivity density0.30.41.30.60.40.5-0.5-0.5-0.50.6-0.6-0.7-0.5-0.5-0.6-0.5-0.9-0.70.40.5-0.30.7-0.81.10.80.1-1.0-0.50.7-0.8
Bone: cortical apparent density5.57.511.5-3.4-3.0-3.23.13.13.1-3.23.33.33.13.13.13.13.43.1-2.1-2.52.1-2.92.9-3.0-2.90.70.10.3-0.60.4
Bone: cortical area0.60.92.7-0.5-0.3-0.50.10.10.1-0.70.50.60.10.20.10.10.70.9-1.5-1.51.5-1.21.0-1.0-1.0-1.11.61.3-1.21.4
Bone: cortical porosity1.71.83.31.51.01.3-1.3-1.2-1.21.5-1.3-1.5-1.1-1.1-1.0-1.1-1.8-1.51.61.8-1.71.6-1.51.61.60.3-1.4-0.70.8-1.1
Bone: cortical porosity2.12.34.71.81.31.6-1.8-1.7-1.71.7-1.6-1.8-1.6-1.6-1.6-1.6-2.2-1.61.51.8-1.61.6-1.51.51.5-0.4-1.1-0.00.1-0.5
Bone: cortical thickness1.52.54.4-1.8-1.5-1.71.81.81.8-1.81.71.91.71.71.71.72.11.7-2.0-2.02.0-1.61.4-1.4-1.40.40.60.1-0.10.3
Bone: cortical thickness0.20.20.5-0.4-0.2-0.20.20.10.1-0.40.20.2-0.1-0.0-0.1-0.10.40.5-0.5-0.50.5-0.60.5-0.4-0.5-0.70.60.7-0.60.6
Bone: cortical tissue density5.37.210.9-3.3-3.0-3.23.03.03.0-3.23.23.23.03.03.03.03.33.1-2.0-2.42.1-2.82.8-3.0-2.90.60.10.4-0.60.4
Condit. Reinf. active minus inactive responses4.24.78.32.52.92.7-2.5-2.4-2.42.6-2.6-2.5-2.5-2.5-2.6-2.6-2.0-2.42.22.1-2.22.0-1.91.91.9-0.81.40.2-0.10.7
Condit. Reinf. active-inactive response ratio2.52.74.51.92.12.0-1.9-1.8-1.82.0-1.9-1.8-1.8-1.9-2.0-1.9-1.4-1.81.71.7-1.81.5-1.31.21.3-0.51.30.2-0.20.7
Condit. Reinf. active responses3.03.86.72.22.62.4-2.4-2.4-2.42.2-2.3-2.2-2.5-2.4-2.4-2.4-1.8-1.91.61.5-1.61.4-1.41.31.3-1.41.70.9-0.71.2
Condit. Reinf. inactive responses0.20.21.20.10.40.2-0.4-0.4-0.4-0.1-0.1-0.0-0.4-0.3-0.3-0.30.10.2-0.5-0.50.6-0.50.3-0.4-0.4-0.91.10.8-0.71.0
Incentive salience index mean3.34.16.42.42.52.5-2.2-2.2-2.22.4-2.4-2.3-2.2-2.2-2.3-2.3-2.0-2.42.22.1-2.22.1-2.12.02.0-0.30.6-0.20.40.0
Condit. Reinf. lever presses1.11.52.81.31.41.3-0.9-0.9-0.91.4-1.3-1.2-0.8-0.9-0.9-0.9-1.0-1.51.51.5-1.51.5-1.71.61.50.7-0.4-1.21.4-1.0
Condit. Reinf. active minus inactive responses2.63.35.72.12.12.2-2.3-2.3-2.32.0-2.2-2.1-2.3-2.3-2.4-2.4-2.0-1.81.21.4-1.31.3-1.21.31.3-1.41.50.8-0.71.1
Condit. Reinf. active-inactive response ratio2.52.94.52.01.92.1-1.9-1.9-1.92.0-2.1-2.0-2.0-1.9-2.0-2.0-2.0-1.91.51.7-1.61.7-1.71.81.8-0.50.4-0.10.20.1
Condit. Reinf. active responses0.71.02.01.01.11.1-1.4-1.3-1.30.9-1.1-1.0-1.3-1.3-1.3-1.3-1.0-0.7-0.00.2-0.00.3-0.20.20.2-1.21.30.9-0.71.0
Condit. Reinf. inactive responses0.40.51.5-0.3-0.3-0.3-0.1-0.1-0.1-0.50.40.40.0-0.00.00.00.30.7-1.2-1.11.2-0.91.0-1.1-1.1-1.00.81.2-1.00.9
Condit. Reinf. lever presses0.10.10.30.3-0.00.3-0.5-0.4-0.40.3-0.3-0.3-0.4-0.3-0.4-0.4-0.6-0.2-0.5-0.20.40.20.2-0.1-0.1-0.3-0.20.3-0.1-0.0
Condit. Reinf. lever reinforcers received0.60.92.20.90.91.0-1.3-1.3-1.30.7-0.9-0.8-1.2-1.2-1.3-1.3-0.8-0.4-0.3-0.10.20.00.0-0.0-0.0-1.41.51.2-0.91.2
Conditioned reinforcement - actives0.10.10.4-0.1-0.3-0.40.20.30.3-0.40.50.50.40.30.60.60.30.4-0.1-0.20.2-0.30.3-0.2-0.40.10.10.2-0.10.1
Conditioned reinforcement - inactives0.10.10.50.20.30.2-0.3-0.4-0.30.1-0.0-0.1-0.4-0.3-0.3-0.3-0.10.00.10.1-0.2-0.20.1-0.1-0.1-0.50.50.7-0.50.6
Conditioned locomotion2.02.54.6-1.5-1.9-1.80.91.11.1-2.01.91.71.11.11.51.41.12.1-1.6-1.61.8-2.12.0-2.0-2.1-1.00.21.7-1.71.1
Patch foraging indifference point 0 sec2.95.412.1-2.8-3.5-2.72.72.72.7-2.52.52.42.72.72.42.41.82.2-3.0-2.42.6-1.72.2-2.1-2.21.2-2.2-0.1-0.2-0.9
Patch foraging indifference point AUC0.50.72.0-0.8-1.4-0.70.20.20.2-0.80.80.40.40.30.00.1-0.20.9-1.2-0.70.9-0.81.2-1.0-1.2-0.9-1.21.3-1.30.3
Delay disc. indifference point, 0s delay0.10.10.50.0-0.5-0.10.10.10.1-0.00.0-0.00.10.10.10.1-0.20.0-0.3-0.10.20.10.20.1-0.10.1-0.7-0.30.2-0.4
Delay disc. indifference point, 16s delay0.60.61.40.91.21.0-0.8-0.8-0.80.9-1.0-0.8-0.8-0.8-0.8-0.8-0.5-0.90.80.8-0.90.8-0.91.10.9-0.00.6-0.50.60.0
Delay disc. indifference point, 2s delay0.00.00.3-0.1-0.2-0.10.00.00.0-0.1-0.00.00.00.0-0.0-0.0-0.20.1-0.3-0.10.2-0.10.10.1-0.0-0.1-0.60.20.0-0.2
Delay disc. indifference point, 24s delay0.20.21.10.10.40.10.20.20.20.2-0.20.00.20.20.20.20.4-0.30.60.4-0.70.4-0.50.60.50.80.3-1.10.9-0.3
Delay disc. indifference point, 4s delay0.40.40.9-0.7-0.9-0.70.70.70.7-0.70.60.70.70.70.60.60.60.6-0.9-0.70.6-0.60.8-0.5-0.60.2-0.4-0.30.2-0.2
Delay disc. indifference point, 8s delay0.30.41.30.50.70.7-0.7-0.7-0.70.6-0.7-0.5-0.7-0.7-0.8-0.8-0.3-0.50.40.4-0.60.3-0.30.50.4-0.51.10.1-0.10.7
Indifference point function ln k0.50.94.4-0.6-0.1-0.51.11.11.1-0.20.40.61.11.00.91.01.0-0.00.20.1-0.30.3-0.50.50.51.7-0.6-1.92.1-1.5
Indifference point function log k0.50.94.4-0.6-0.1-0.51.11.11.1-0.20.40.61.11.00.91.01.0-0.00.20.1-0.30.3-0.50.50.51.7-0.6-1.92.1-1.5
Patch foraging total patch changes 0 sec2.95.412.6-2.7-3.5-2.72.72.72.7-2.42.52.32.62.62.42.41.62.2-3.0-2.42.6-1.62.2-2.1-2.21.2-2.4-0.1-0.2-1.0
Patch foraging total patch changes 12 sec0.91.13.7-1.1-1.9-1.10.70.80.8-1.11.00.80.80.70.60.60.21.1-1.8-1.31.5-0.91.4-1.1-1.3-0.3-1.30.9-1.10.1
Patch foraging total patch changes 18 sec1.62.45.8-1.8-2.4-1.81.61.71.7-1.61.81.51.71.51.51.50.81.5-1.9-1.41.7-1.11.5-1.4-1.60.6-2.30.3-0.3-0.9
Patch foraging total patch changes 24 sec0.81.33.6-1.3-1.9-1.31.11.21.2-1.21.21.01.11.00.90.90.41.1-1.9-1.31.6-0.81.1-1.0-1.20.2-1.70.4-0.6-0.4
Patch foraging total patch changes 6 sec3.24.911.8-2.5-3.4-2.62.32.42.4-2.42.52.22.42.32.32.31.42.3-2.9-2.32.6-1.72.1-1.9-2.10.8-2.40.2-0.2-0.9
Patch foraging time to switch 0 sec0.71.42.71.71.61.4-1.2-1.2-1.21.3-1.4-1.2-1.4-1.3-0.9-0.9-0.9-1.31.31.1-1.21.1-1.31.41.5-0.11.0-0.10.20.3
Patch foraging water rate 0 sec0.51.12.1-1.4-1.2-1.31.11.11.1-1.21.11.21.41.31.11.11.01.1-1.0-1.11.1-1.00.9-0.9-1.00.3-0.5-0.30.3-0.4
Patch foraging water rate 12 sec0.20.41.3-0.5-0.2-0.50.70.80.8-0.30.40.50.80.70.70.70.60.20.1-0.0-0.20.0-0.3-0.00.20.9-0.6-1.01.1-1.0
Patch foraging water rate 18 sec0.30.52.3-0.00.60.20.40.30.30.3-0.4-0.10.30.30.20.20.3-0.51.00.7-1.00.6-1.00.80.81.10.2-1.41.5-0.8
Patch foraging water rate 24 sec0.10.11.3-0.10.60.1-0.0-0.1-0.1-0.0-0.20.0-0.0-0.0-0.1-0.10.40.1-0.1-0.30.3-0.3-0.20.20.1-0.31.1-0.10.20.4
Patch foraging water rate 6 sec0.81.23.2-1.2-0.7-1.01.51.51.5-0.80.80.91.51.41.31.31.10.5-0.0-0.30.1-0.1-0.20.00.01.6-1.0-1.71.8-1.5
Seeking ratio, delayed vs. immediate footshock1.72.03.91.81.51.7-2.0-2.0-1.91.5-1.8-1.7-2.0-2.0-1.7-1.6-1.8-1.31.01.1-0.71.0-0.90.80.8-1.20.50.7-0.60.6
Distance traveled before self-admin3.34.37.82.72.12.4-2.7-2.8-2.82.2-2.3-2.5-2.7-2.8-2.5-2.5-2.8-2.01.61.8-1.41.7-1.51.71.6-1.40.00.6-0.60.4
Distance traveled after self-admin1.31.63.21.81.41.5-1.7-1.6-1.61.4-1.4-1.4-1.6-1.6-1.4-1.4-1.5-1.21.21.2-1.11.0-0.70.80.7-0.80.60.6-0.50.6
Extensor digitorum longus weight6.123.937.9-5.4-5.2-5.34.14.14.1-5.85.45.44.34.24.24.25.26.0-5.8-5.95.8-6.26.0-6.0-6.1-1.62.32.9-3.02.8
Bone: elastic displacement1.01.22.60.90.60.8-0.3-0.3-0.31.1-0.8-0.8-0.2-0.3-0.2-0.2-0.7-1.31.41.4-1.51.5-1.31.51.31.4-1.1-1.51.6-1.5
Bone: elastic work1.31.62.51.41.31.5-1.5-1.5-1.51.4-1.5-1.5-1.5-1.5-1.6-1.5-1.4-1.41.41.4-1.41.2-1.01.21.0-0.60.20.20.10.0
Bone: endosteal estimation2.24.79.72.42.02.3-3.1-3.1-3.11.9-2.3-2.3-2.9-2.9-2.9-2.9-2.7-1.50.51.0-0.50.9-0.70.90.8-2.81.62.2-2.01.9
Bone: endosteal perimeter0.91.93.71.51.51.5-1.9-1.9-1.91.2-1.4-1.4-1.8-1.8-1.8-1.8-1.3-0.90.20.4-0.20.4-0.50.40.4-1.71.81.4-1.21.5
Epididymis fat weight0.51.89.40.20.80.7-1.1-1.1-1.10.2-0.6-0.5-1.1-1.2-1.5-1.5-0.10.2-0.3-0.40.1-0.90.8-0.7-0.8-2.53.12.3-2.22.7
Delta time in closed arm before/after self-admin0.50.51.2-1.1-0.8-0.80.80.90.9-0.80.80.80.80.90.60.60.80.8-0.9-0.70.6-0.70.6-0.6-0.60.1-0.20.4-0.30.1
Delta time in open arm before/after self-admin3.63.66.12.51.82.2-2.3-2.3-2.32.1-2.1-2.2-2.3-2.4-2.1-2.1-2.5-2.02.12.1-1.81.8-1.61.61.6-0.8-0.5-0.0-0.1-0.1
Diff in mean of infusions in LGA sessions0.91.12.11.31.51.3-1.1-1.2-1.21.3-1.3-1.2-1.1-1.1-1.1-1.1-0.9-1.21.11.1-1.11.1-1.01.01.0-0.20.60.10.20.1
Delay discount exponential model param0.00.00.30.0-0.0-0.0-0.1-0.1-0.1-0.00.1-0.0-0.1-0.1-0.0-0.0-0.20.1-0.0-0.10.3-0.00.0-0.3-0.2-0.2-0.30.5-0.50.1
Extinction: sum of active levers before priming0.80.92.01.41.31.2-1.1-1.1-1.11.3-1.1-1.1-1.0-1.0-0.9-1.0-0.8-1.20.70.7-0.71.1-1.00.90.90.00.4-0.30.10.1
Active lever presses in extinction session 61.21.22.91.21.21.1-0.9-0.9-0.91.2-1.2-1.1-1.0-1.0-0.9-0.9-0.9-1.21.71.5-1.71.2-1.11.11.10.10.1-0.90.8-0.4
Bone: final force0.71.14.20.60.50.6-1.3-1.2-1.20.2-0.5-0.5-1.1-1.0-1.1-1.1-0.70.1-0.7-0.50.8-0.60.5-0.3-0.4-2.01.81.7-1.51.7
Bone: final moment0.40.72.80.30.20.2-0.9-0.8-0.8-0.1-0.2-0.2-0.7-0.6-0.7-0.7-0.40.4-1.0-0.81.0-0.70.6-0.3-0.5-1.71.51.4-1.21.3
Food consumed during 24 hour testing period0.40.51.80.50.20.4-0.9-0.9-0.90.2-0.4-0.5-0.8-0.9-0.8-0.8-0.8-0.00.20.3-0.2-0.2-0.10.40.1-1.40.41.3-1.30.9
Glucose0.50.83.7-0.2-0.1-0.30.80.80.80.10.10.20.80.80.80.80.3-0.40.50.5-0.50.8-0.80.60.71.9-1.4-1.81.6-1.6
Heart weight0.10.20.40.30.40.5-0.6-0.6-0.60.4-0.5-0.5-0.6-0.5-0.6-0.7-0.4-0.30.20.3-0.40.2-0.00.20.1-0.60.40.4-0.10.2
Delay discount hyperbolic model param0.00.00.30.10.10.1-0.2-0.2-0.20.00.0-0.1-0.2-0.2-0.1-0.1-0.2-0.00.10.00.10.0-0.0-0.3-0.1-0.2-0.20.5-0.50.1
Intermittent access intake day 1-15 change0.40.81.8-1.3-1.1-0.81.11.21.2-0.80.80.91.01.10.70.71.30.7-0.9-0.70.2-0.61.1-1.2-1.10.50.10.1-0.00.1
Intermittent access intake escalation0.61.32.6-1.5-1.5-1.11.51.61.6-1.01.11.11.41.41.11.11.50.9-1.2-0.90.5-0.71.2-1.2-1.10.8-0.2-0.20.2-0.2
Intermittent access intake escalation 20.30.30.9-0.8-0.7-0.30.90.90.9-0.20.30.30.80.80.40.40.70.0-0.4-0.1-0.30.10.3-0.3-0.21.0-0.5-0.70.6-0.6
Intermitt. access day 1 inactive lever presses0.72.85.5-1.7-1.9-1.92.32.32.2-1.51.91.82.32.22.12.21.71.3-1.3-1.21.0-0.70.8-0.8-0.91.9-1.5-0.81.0-1.3
Intermitt. access day 15 inactive lever presses0.10.20.7-0.10.1-0.40.50.40.4-0.40.50.50.50.40.80.80.60.3-0.1-0.30.2-0.2-0.20.00.00.40.1-0.20.2-0.1
Intermitt. access escalation Index0.20.31.2-0.50.2-0.20.80.70.7-0.10.10.40.70.60.50.51.00.00.0-0.1-0.30.0-0.40.20.20.90.6-1.10.9-0.2
Intermittent access day 1 total infusions0.20.40.90.80.80.6-0.5-0.5-0.50.8-0.6-0.6-0.4-0.30.0-0.1-0.6-0.80.50.5-0.50.9-0.90.70.80.7-0.2-0.60.7-0.6
Intermittent access day 15 total infusions0.71.12.3-1.2-0.9-1.01.51.51.5-0.70.91.11.41.51.51.41.40.6-0.9-0.80.4-0.30.5-0.6-0.41.5-0.4-0.70.9-0.7
Intermittent access terminal intake (last 3 days)1.21.63.2-1.5-1.2-1.31.81.81.8-1.01.21.31.71.81.71.61.60.8-1.0-0.90.5-0.40.5-0.8-0.51.6-0.7-0.80.9-0.9
Intermittent access total infusions0.20.21.0-0.3-0.1-0.20.50.50.5-0.10.20.30.40.60.80.60.4-0.1-0.3-0.20.10.2-0.2-0.00.21.0-0.3-0.60.8-0.6
Intermittent access day 1 locomotion0.00.00.10.10.2-0.0-0.1-0.1-0.0-0.00.10.1-0.1-0.00.30.2-0.00.10.30.1-0.1-0.0-0.10.00.0-0.00.10.00.00.1
Intermittent access day 15 total locomotion0.30.61.3-0.5-0.7-0.80.20.40.3-0.90.90.80.40.60.90.80.61.0-0.9-0.90.9-1.01.1-1.1-1.0-0.50.60.7-0.60.6
Intermittent access total locomotion0.50.61.8-0.8-0.9-1.00.70.90.9-0.90.91.00.81.01.31.20.70.8-0.8-0.80.8-0.60.6-0.7-0.60.5-0.3-0.40.3-0.3
Intermittent access standard deviation0.30.61.5-1.2-1.2-0.80.91.00.9-0.80.80.80.90.80.50.50.80.8-1.2-0.80.6-0.71.0-1.0-1.00.2-0.30.3-0.2-0.1
Left kidney weight0.00.20.40.50.60.6-0.5-0.5-0.50.6-0.5-0.5-0.2-0.5-0.5-0.5-0.4-0.50.50.5-0.60.5-0.40.40.40.00.5-0.10.10.1
Right kidney weight0.10.61.4-0.8-0.8-0.70.40.50.5-0.80.70.70.60.50.30.30.70.9-1.1-1.00.9-1.11.0-1.2-1.1-0.60.80.8-0.60.7
Cocaine induced anxiety1.01.42.4-1.5-1.3-1.41.41.41.4-1.41.41.51.51.41.41.41.51.4-0.8-1.10.9-1.21.1-1.0-1.00.40.1-0.00.1-0.0
Post-drug Anxiety1.41.52.3-1.4-1.2-1.41.21.21.2-1.51.41.51.31.21.21.21.51.5-1.3-1.51.4-1.51.3-1.3-1.3-0.10.60.6-0.40.6
Baseline Anxiety0.91.01.81.31.21.2-1.3-1.3-1.31.1-1.2-1.2-1.3-1.3-1.4-1.3-1.1-1.00.40.6-0.40.7-0.80.60.7-0.70.60.6-0.50.5
Tail length3.714.322.74.64.84.5-4.6-4.6-4.64.2-4.3-4.2-4.4-4.3-4.2-4.3-4.0-3.93.83.7-3.73.2-3.53.63.4-1.71.90.4-0.21.0
Length with tail4.117.630.34.95.14.9-5.5-5.4-5.44.3-4.7-4.6-5.2-5.2-5.1-5.3-4.3-3.73.63.5-3.52.7-2.72.82.7-3.53.52.2-2.12.8
Length without tail1.44.711.01.81.82.1-2.8-2.8-2.81.5-2.0-2.0-2.7-2.8-2.9-2.9-2.1-1.00.81.0-0.90.20.0-0.1-0.0-3.32.62.9-2.82.8
Times rat made contact with spout1.01.13.50.60.40.30.20.20.20.7-0.4-0.40.30.10.30.3-0.5-1.01.11.0-1.01.4-1.51.51.41.8-1.7-1.91.6-1.7
Lifetime Intake0.30.41.3-0.6-0.6-0.60.80.80.8-0.50.50.70.60.81.21.00.70.4-0.8-0.70.7-0.30.3-0.4-0.20.7-0.2-0.20.4-0.3
Liver weight, left0.61.02.71.10.91.0-1.4-1.5-1.50.7-0.8-0.9-1.3-1.5-1.4-1.4-1.0-0.40.20.3-0.20.0-0.20.20.2-1.61.21.2-0.91.1
Liver weight, right0.30.51.20.60.80.8-0.9-0.9-0.90.6-0.8-0.8-1.0-1.1-1.1-1.1-0.6-0.50.40.5-0.50.3-0.40.30.3-0.90.70.7-0.50.6
Locomotor activity0.00.10.2-0.4-0.3-0.20.30.30.3-0.20.10.20.20.20.10.00.30.2-0.5-0.40.4-0.20.1-0.1-0.2-0.0-0.10.1-0.20.1
Locomotor testing distance0.10.20.90.10.00.30.10.10.10.4-0.4-0.4-0.0-0.1-0.2-0.2-0.3-0.60.30.4-0.40.7-0.60.60.60.7-1.0-0.70.6-0.8
Locomotor testing rearing0.20.52.5-0.3-0.2-0.30.90.90.9-0.00.20.30.80.80.70.70.6-0.20.10.1-0.30.5-0.60.40.51.6-0.6-1.31.1-1.0
Locomotion in novel chamber2.22.86.3-1.7-2.0-1.60.90.90.8-1.91.71.50.90.90.90.91.12.1-2.1-1.92.0-2.22.5-2.4-2.4-1.40.51.7-1.81.3
Locomotion in novel chamber post-restriction1.42.36.4-1.4-1.6-1.50.90.90.8-1.81.41.50.90.91.11.11.12.0-2.2-2.22.5-2.12.0-1.8-1.9-1.20.71.1-1.21.1
Fecal boli incidents, locomotor time 10.10.20.80.10.20.1-0.1-0.0-0.10.2-0.1-0.20.0-0.1-0.0-0.1-0.3-0.30.90.8-0.80.4-0.60.20.40.4-0.9-0.10.3-0.6
Change in fecal boli incidents, locomotor task0.10.10.9-0.1-0.1-0.20.40.40.4-0.10.10.30.40.40.40.40.30.1-0.3-0.20.1-0.0-0.00.10.10.50.3-0.81.0-0.5
Time >=10cm from walls, locomotor time 10.80.82.6-0.6-0.8-0.40.1-0.10.1-0.70.50.50.10.1-0.0-0.00.40.9-1.3-1.01.0-1.11.2-1.2-1.2-1.21.01.6-1.61.4
Bouts of movement, locomotor time 10.80.91.7-1.0-0.9-1.21.11.11.1-1.11.01.21.21.11.31.31.11.0-1.0-1.01.0-0.80.7-0.9-0.70.6-0.3-0.10.2-0.2
Total resting periods, locomotor time 11.41.52.4-1.4-1.2-1.51.41.31.4-1.41.31.51.41.41.51.51.41.4-1.3-1.31.3-1.21.1-1.4-1.10.4-0.10.2-0.10.0
Rest time, locomotor task time 10.30.41.1-0.5-0.4-0.60.90.90.9-0.40.50.60.90.90.90.90.50.3-0.2-0.20.1-0.0-0.1-0.20.11.1-0.6-0.71.0-0.9
Distance moved, locomotor task time 10.20.20.70.60.70.7-0.5-0.7-0.50.6-0.7-0.5-0.5-0.5-0.6-0.6-0.1-0.50.30.2-0.30.3-0.50.60.4-0.20.9-0.30.10.3
Vertical activity count, locomotor time 10.00.00.20.1-0.20.1-0.1-0.3-0.10.0-0.1-0.0-0.1-0.1-0.2-0.20.00.0-0.2-0.20.1-0.10.20.1-0.1-0.20.40.0-0.20.3
Time >=10cm from walls, locomotor time 20.91.42.11.40.91.4-1.2-1.3-1.21.4-1.2-1.4-1.1-1.2-1.3-1.2-1.3-1.41.21.3-1.41.4-1.11.31.00.1-0.4-0.90.8-0.6
Bouts of movement, locomotor time 22.03.25.5-2.0-1.8-2.12.02.12.0-2.11.92.22.12.02.12.12.32.0-1.9-2.01.7-1.81.8-1.7-1.70.70.6-0.20.40.0
Total resting periods, locomotor time 21.83.24.8-2.0-1.9-2.12.02.12.0-2.02.02.22.12.02.12.12.21.9-1.9-1.91.7-1.71.8-1.7-1.60.70.3-0.30.4-0.1
Rest time, locomotor task time 20.91.12.5-1.1-1.3-1.21.21.61.2-1.01.11.01.41.21.41.40.70.8-0.5-0.50.5-0.30.5-0.5-0.41.2-1.6-0.70.9-1.2
Distance moved, locomotor task time 20.50.61.40.81.11.0-0.8-1.1-0.80.8-0.9-0.8-1.0-0.8-1.1-1.0-0.4-0.70.30.2-0.20.3-0.50.50.4-0.71.20.4-0.50.9
Vertical activity count, locomotor time 20.00.00.2-0.10.10.00.30.00.30.00.10.10.10.30.00.10.4-0.1-0.0-0.2-0.0-0.0-0.20.20.10.30.5-0.50.4-0.0
Light reinforcement 13.38.013.5-3.5-3.7-3.33.03.03.0-3.43.33.22.82.82.72.72.93.4-3.1-3.02.9-3.13.1-3.0-3.1-0.0-0.41.2-1.30.6
Light reinforcement 20.71.02.5-1.4-1.6-1.31.11.11.1-1.31.31.21.01.11.01.00.91.3-0.7-0.70.7-1.11.1-1.0-1.10.0-0.70.3-0.2-0.2
Bone: marrow area2.04.49.02.31.92.2-3.0-3.0-3.01.8-2.2-2.2-2.8-2.8-2.8-2.8-2.6-1.40.40.8-0.40.8-0.60.80.7-2.71.62.1-1.91.9
Bone: maximum diameter0.10.31.2-0.10.0-0.2-0.0-0.0-0.0-0.30.20.30.10.10.10.10.40.4-1.0-1.01.1-0.50.4-0.3-0.3-0.51.10.5-0.40.7
Bone: maximum force1.22.17.41.10.81.0-2.0-1.9-1.90.6-1.0-1.0-1.7-1.7-1.8-1.7-1.4-0.1-0.5-0.20.6-0.40.3-0.3-0.3-2.71.92.3-2.02.0
Bone: maximum moment0.71.35.20.70.40.7-1.5-1.4-1.40.3-0.6-0.7-1.3-1.2-1.3-1.3-1.10.1-0.8-0.50.8-0.50.4-0.3-0.4-2.31.51.9-1.61.6
Mean time between licks in bursts1.33.26.3-2.0-2.4-2.01.51.61.6-2.12.01.91.51.61.41.41.52.1-2.5-2.22.4-2.12.2-2.3-2.2-0.5-0.11.0-0.80.5
Mean num. licks in bursts0.10.10.5-0.0-0.3-0.1-0.1-0.1-0.1-0.20.10.1-0.1-0.1-0.1-0.0-0.10.3-0.4-0.30.4-0.30.6-0.5-0.5-0.50.10.6-0.70.5
Cd content in liver2.32.64.81.82.21.9-1.6-1.6-1.62.0-2.0-1.8-1.6-1.4-1.4-1.4-1.4-2.01.81.7-1.81.8-1.81.91.80.20.5-0.60.8-0.2
Co content in liver1.11.32.71.11.41.1-0.5-0.5-0.51.3-1.1-0.9-0.5-0.4-0.4-0.4-0.6-1.41.51.3-1.51.5-1.61.51.41.2-0.3-1.51.7-1.1
Cu content in liver1.51.72.81.41.61.5-1.1-1.1-1.11.6-1.6-1.4-1.2-1.2-1.3-1.3-1.1-1.61.71.6-1.71.5-1.41.61.40.30.2-0.71.0-0.5
Fe content in liver2.53.16.11.81.61.7-1.2-1.2-1.22.0-1.9-1.8-1.2-1.2-1.2-1.2-1.8-2.22.22.2-2.22.3-2.22.52.31.1-1.1-1.61.6-1.5
K content in liver1.91.94.8-1.6-2.2-1.61.21.21.2-1.61.51.31.11.01.11.00.71.6-1.7-1.41.7-1.41.9-1.6-1.8-0.3-1.01.0-1.10.2
Mg content in liver0.50.51.7-0.8-1.3-0.80.70.70.7-0.70.70.60.70.70.70.70.20.7-0.9-0.60.9-0.40.7-0.5-0.70.3-1.10.2-0.3-0.4
Mn content in liver0.50.61.6-0.6-1.0-0.80.90.80.8-0.60.60.60.91.01.01.00.30.4-0.6-0.50.6-0.10.3-0.1-0.31.0-1.3-0.90.8-1.1
Na content in liver0.10.10.90.1-0.40.00.00.00.00.1-0.1-0.2-0.1-0.2-0.2-0.2-0.5-0.20.00.2-0.00.30.00.20.10.1-0.9-0.10.1-0.5
Rb content in liver3.13.66.2-1.8-1.6-1.81.31.31.3-2.11.92.01.41.31.31.32.12.3-2.3-2.42.2-2.52.4-2.5-2.5-1.11.81.7-2.02.0
Se content in liver0.20.20.6-0.5-0.7-0.50.50.50.5-0.50.60.50.50.20.20.20.40.5-0.3-0.30.2-0.40.6-0.3-0.60.1-0.3-0.00.0-0.1
Sr content in liver0.20.20.4-0.4-0.6-0.40.50.50.5-0.30.40.40.50.50.50.50.40.3-0.3-0.40.3-0.20.5-0.6-0.60.5-0.1-0.10.0-0.1
Zn content in liver0.00.00.2-0.3-0.2-0.20.20.20.2-0.20.10.20.10.20.10.10.20.1-0.4-0.30.4-0.10.2-0.3-0.30.10.10.2-0.10.0
Bone: minimum diameter0.51.03.60.40.30.4-1.1-1.0-1.0-0.0-0.3-0.3-0.9-0.9-0.9-0.9-0.60.3-1.2-0.91.2-0.70.6-0.6-0.5-1.91.31.7-1.61.6
Time in familiar zone, hab. session 10.30.31.0-0.4-0.3-0.40.70.80.8-0.30.40.50.70.70.70.80.60.10.2-0.0-0.20.0-0.10.10.01.0-0.2-0.91.0-0.7
Time in novel zone, hab. session 13.33.34.72.12.02.1-2.0-2.0-2.02.1-2.1-2.2-1.9-2.0-2.0-2.0-2.2-2.11.92.0-1.91.9-1.81.81.8-0.3-0.2-0.30.3-0.3
Total zone transitions, hab. session 10.40.62.80.0-0.00.1-0.6-0.6-0.6-0.20.1-0.0-0.5-0.5-0.5-0.5-0.10.5-0.2-0.30.3-0.80.8-0.9-0.8-1.61.01.7-1.71.5
Total locomotion distance, hab. session 11.11.67.20.40.30.5-1.3-1.3-1.3-0.0-0.4-0.5-1.3-1.2-1.3-1.4-0.70.4-0.7-0.50.7-0.90.7-0.9-0.8-2.71.62.4-2.22.1
Locomotion velocity, hab. session 11.11.55.7-0.4-0.5-0.3-0.5-0.5-0.5-0.80.40.3-0.5-0.5-0.5-0.60.01.1-1.5-1.31.5-1.51.3-1.4-1.3-2.41.32.3-2.32.0
Time in familiar zone, hab. session 20.10.10.30.20.20.20.00.00.00.3-0.1-0.2-0.0-0.00.00.0-0.1-0.30.50.4-0.50.4-0.40.50.50.5-0.4-0.40.3-0.3
Time in novel zone, hab. session 20.00.00.20.10.30.10.00.10.10.2-0.2-0.10.10.10.10.1-0.0-0.30.00.0-0.00.3-0.30.00.20.50.0-0.40.2-0.2
Total zone transitions, hab. session 20.00.00.10.00.2-0.00.10.10.10.10.00.10.10.20.20.20.2-0.10.10.0-0.10.1-0.2-0.00.20.30.1-0.30.2-0.0
Total locomotion distance, hab. session 20.40.52.40.50.60.5-0.7-0.7-0.70.3-0.5-0.4-0.8-0.7-0.8-0.8-0.3-0.1-0.4-0.40.5-0.30.1-0.3-0.2-1.21.51.0-1.01.3
Locomotion velocity, hab. session 20.40.62.70.30.50.3-0.6-0.6-0.60.0-0.3-0.2-0.6-0.6-0.7-0.7-0.10.2-0.6-0.60.7-0.50.3-0.6-0.4-1.31.61.2-1.21.5
Novel to familiar place preference ratio1.31.42.11.41.21.4-1.3-1.4-1.41.4-1.4-1.4-1.3-1.4-1.4-1.4-1.4-1.41.21.3-1.21.3-1.01.11.0-0.20.2-0.10.2-0.1
Novelty place preference1.11.11.81.31.11.2-1.0-1.1-1.11.3-1.3-1.3-1.0-1.1-1.1-1.2-1.2-1.31.11.2-1.11.3-1.01.21.10.2-0.1-0.50.5-0.4
Time in novel zone, NPP test1.31.42.21.41.31.4-1.1-1.2-1.21.5-1.4-1.4-1.1-1.2-1.2-1.2-1.3-1.51.21.3-1.21.5-1.21.31.20.2-0.1-0.60.6-0.4
Total zone transitions, NPP test0.30.51.3-0.7-0.3-0.70.70.70.7-0.70.70.80.60.70.70.71.10.8-0.5-0.80.6-0.80.7-0.9-0.7-0.01.00.3-0.20.6
Total locomotion distance, NPP test0.20.31.30.10.10.1-0.4-0.4-0.4-0.1-0.1-0.1-0.5-0.4-0.5-0.5-0.20.3-0.6-0.40.6-0.50.3-0.3-0.3-1.10.71.0-0.80.8
Locomotion velocity, NPP test0.30.41.1-0.4-0.4-0.4-0.00.00.0-0.60.30.3-0.10.0-0.1-0.10.10.7-0.9-0.81.0-0.80.6-0.7-0.7-1.00.51.1-0.90.7
Intraocular pressure0.20.30.8-0.6-0.2-0.50.80.90.9-0.40.40.50.80.70.60.70.90.3-0.4-0.50.4-0.20.1-0.0-0.10.8-0.1-0.60.7-0.5
Delta distance traveled before/after self-admin0.30.41.1-0.4-0.3-0.60.70.70.7-0.50.70.80.70.80.80.81.00.5-0.2-0.50.2-0.50.5-0.6-0.60.40.8-0.00.10.3
Delta ambulatory time before/after self-admin0.50.61.6-0.8-0.6-0.80.90.90.9-0.80.91.00.91.00.80.81.30.8-0.7-0.90.6-0.80.9-0.9-0.90.30.90.10.00.4
Parametrial fat weight0.40.91.8-0.9-0.6-1.11.31.31.3-1.00.91.11.31.21.31.41.20.8-0.8-0.90.9-0.60.2-0.1-0.11.0-0.2-1.11.1-0.7
Pavlov. Cond. lever latency2.53.15.0-2.0-2.0-1.91.51.51.5-2.11.91.91.41.51.51.51.82.2-2.0-2.12.0-2.22.2-2.0-2.1-0.71.01.2-1.31.2
Pavlov. Cond. magazine entry latency3.14.05.92.32.42.3-2.1-2.1-2.12.3-2.3-2.3-2.1-2.1-2.2-2.2-2.2-2.32.42.4-2.42.1-2.11.92.0-0.30.2-0.20.4-0.2
Pavlov. Cond. change in total contacts2.12.23.81.81.91.8-1.5-1.5-1.51.9-1.8-1.7-1.4-1.5-1.6-1.6-1.5-1.81.41.5-1.51.7-1.71.61.60.00.5-0.60.7-0.2
Pavlov. Cond. index score3.03.85.92.22.22.1-1.7-1.7-1.72.4-2.1-2.2-1.6-1.7-1.8-1.8-2.0-2.42.32.3-2.42.4-2.42.22.30.6-0.7-1.21.4-1.2
Pavlov. Cond. latency score3.14.05.92.22.32.2-1.8-1.8-1.82.4-2.2-2.2-1.7-1.8-1.9-1.9-2.1-2.42.42.4-2.42.4-2.42.22.30.5-0.6-1.01.2-1.0
Pavlov. Cond. lever contacts2.32.84.91.91.81.7-1.3-1.3-1.32.0-1.7-1.8-1.2-1.3-1.4-1.4-1.7-2.11.81.9-1.92.1-2.22.02.10.8-0.9-1.41.5-1.3
Pavlov. Cond. magazine entry number4.25.37.6-2.6-2.7-2.72.32.32.3-2.72.62.62.32.32.42.42.42.7-2.8-2.72.7-2.52.6-2.5-2.50.0-0.00.7-0.90.5
Pavlov. Cond. intertrial magazine entries0.10.10.8-0.3-0.0-0.10.20.20.2-0.30.10.30.00.10.10.10.60.3-0.6-0.70.6-0.50.4-0.2-0.3-0.30.90.3-0.20.6
Pavlov. Cond. lever-magazine prob. diff.2.73.35.02.12.12.0-1.7-1.6-1.62.2-2.0-2.0-1.6-1.6-1.8-1.8-1.9-2.22.12.2-2.22.2-2.22.02.10.4-0.5-1.01.2-0.9
Pavlov. Cond. response bias3.54.36.32.42.42.3-1.9-1.9-1.92.5-2.3-2.3-1.9-1.9-2.0-2.0-2.1-2.52.52.4-2.52.4-2.52.32.40.4-0.3-1.11.2-0.9
Pavlov. Cond. lever latency0.20.30.7-0.5-0.2-0.50.70.70.7-0.50.50.60.70.60.80.70.90.40.1-0.20.0-0.40.1-0.1-0.10.50.4-0.50.4-0.1
Pavlov. Cond. magazine entry latency0.30.30.70.60.40.7-0.7-0.7-0.70.6-0.7-0.7-0.8-0.7-0.9-0.8-0.8-0.60.00.3-0.10.5-0.40.50.3-0.4-0.10.3-0.30.1
Pavlov. Cond. change in total contacts0.71.12.21.20.91.2-1.3-1.3-1.31.2-1.2-1.3-1.3-1.3-1.4-1.3-1.5-1.10.70.9-0.81.0-0.60.70.6-0.6-0.30.4-0.40.1
Pavlov. Cond. index score0.40.61.40.80.40.9-1.1-1.0-1.00.8-0.8-0.9-1.1-1.0-1.2-1.1-1.2-0.6-0.00.3-0.10.5-0.20.30.2-0.8-0.20.7-0.70.4
Pavlov. Cond. latency score0.40.61.40.70.30.8-1.1-1.0-1.00.6-0.7-0.9-1.1-1.0-1.2-1.1-1.1-0.5-0.10.2-0.00.3-0.00.20.0-1.0-0.00.9-0.90.5
Pavlov. Cond. lever contacts0.40.61.50.90.50.9-1.0-1.0-1.00.9-0.9-1.0-1.0-0.9-1.0-1.0-1.2-0.80.20.5-0.30.8-0.50.50.6-0.4-0.60.2-0.1-0.2
Pavlov. Cond. magazine entry number0.40.51.4-0.8-0.4-0.80.90.90.9-0.80.81.00.90.81.01.01.20.8-0.4-0.60.4-0.80.5-0.6-0.50.30.6-0.20.20.1
Pavlov. Cond. intertrial magazine entries0.50.81.6-0.9-0.8-1.01.11.11.1-1.01.01.11.21.11.21.21.30.9-0.7-0.90.8-0.80.6-0.6-0.60.60.2-0.50.7-0.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.90.60.20.6-0.8-0.8-0.80.5-0.6-0.7-0.8-0.7-0.9-0.9-0.9-0.4-0.20.10.10.30.00.1-0.0-0.7-0.20.7-0.70.3
Pavlov. Cond. response bias0.81.12.61.20.81.2-1.4-1.4-1.41.1-1.2-1.3-1.4-1.3-1.5-1.5-1.6-1.00.30.6-0.30.9-0.60.60.6-0.8-0.30.6-0.60.2
Time in closed arm before self-admin1.72.14.01.71.31.7-1.7-1.8-1.81.6-1.6-1.8-1.8-1.8-1.7-1.7-2.0-1.51.51.6-1.31.4-1.01.11.2-0.7-0.3-0.30.3-0.3
Time in closed arm after self-admin0.20.20.50.40.30.5-0.5-0.6-0.60.5-0.5-0.6-0.6-0.6-0.7-0.7-0.5-0.40.30.4-0.40.30.00.10.1-0.50.20.5-0.20.2
Time in open arm before self-admin2.12.35.7-1.9-1.0-1.61.71.71.7-1.61.61.81.71.81.51.52.41.6-1.5-1.71.2-1.71.3-1.4-1.40.31.50.5-0.61.0
Time in open arm after self-admin2.42.64.41.91.71.8-2.1-2.1-2.11.6-1.8-1.8-2.0-2.1-1.9-1.9-1.9-1.51.61.6-1.51.2-1.11.21.2-1.20.50.7-0.80.7
Bone: periosteal estimation1.12.35.71.41.31.4-2.1-2.1-2.11.0-1.4-1.3-2.0-1.9-2.0-2.0-1.5-0.6-0.5-0.10.50.1-0.10.10.2-2.41.92.0-1.92.0
Bone: periosteal perimeter0.50.82.51.01.21.0-1.2-1.2-1.20.8-0.9-0.8-1.1-1.1-1.1-1.1-0.7-0.6-0.2-0.10.20.3-0.40.30.4-1.01.60.8-0.71.1
Bone: post-yield work0.71.02.61.00.91.0-1.4-1.4-1.40.7-0.9-0.9-1.3-1.3-1.3-1.3-1.1-0.40.10.3-0.10.1-0.20.10.2-1.61.01.2-1.01.1
Progressive ratio test 1 active lever presses0.70.81.4-1.0-1.0-0.91.11.11.1-0.81.01.01.11.21.11.11.20.8-1.1-1.00.7-0.60.8-0.9-0.80.8-0.0-0.10.2-0.1
Progressive ratio test 1 breakpoint0.40.50.9-0.8-0.7-0.70.80.80.8-0.60.80.80.80.90.80.80.90.6-0.9-0.80.6-0.50.7-0.8-0.70.50.1-0.00.10.0
Progressive ratio test 1 inactive lever presses1.42.13.3-1.7-1.6-1.71.71.61.7-1.51.71.71.61.71.81.71.81.5-1.4-1.41.0-1.31.4-1.4-1.40.70.10.4-0.10.1
Progressive ratio test 2 active lever presses0.30.30.9-0.7-0.5-0.50.70.70.7-0.40.40.60.70.70.70.60.90.4-0.8-0.70.5-0.30.6-0.5-0.40.50.5-0.10.30.0
Progressive ratio test 2 breakpoint0.40.41.1-0.7-0.5-0.50.80.90.9-0.50.50.70.80.90.90.81.00.4-0.9-0.80.5-0.30.5-0.4-0.40.70.4-0.30.5-0.1
Progressive ratio test 2 inactive lever presses0.20.40.8-0.5-0.7-0.50.70.70.7-0.40.60.60.70.70.70.70.90.4-0.6-0.60.2-0.40.7-0.8-0.80.50.40.2-0.00.2
Incentive Sensitization - Responses0.10.10.60.40.50.5-0.3-0.2-0.20.5-0.6-0.3-0.4-0.3-0.2-0.20.0-0.5-0.1-0.10.00.4-0.20.30.30.10.8-0.30.40.1
Incentive Sensitization - Breakpoint0.10.10.50.20.40.3-0.1-0.0-0.10.3-0.3-0.1-0.1-0.00.10.00.2-0.3-0.3-0.20.20.2-0.10.20.20.30.7-0.30.40.0
Sum of active levers in priming session hrs 5-63.12.95.32.12.32.1-2.0-2.0-2.02.0-1.9-1.9-2.0-2.0-2.0-2.1-1.5-1.81.61.6-1.81.4-1.41.41.4-0.81.2-0.10.00.5
Progressive ratio0.61.03.2-0.6-0.2-0.60.30.30.4-0.90.60.80.30.30.30.41.21.0-1.3-1.41.4-1.31.1-1.0-1.1-1.01.81.2-1.11.5
Food seeking constrained by brief footshock0.60.72.0-0.5-0.6-0.30.10.10.1-0.60.50.40.00.0-0.1-0.20.60.8-1.1-0.90.7-1.01.2-1.2-1.3-1.11.11.4-1.41.4
Seeking ratio, punishment vs. effort0.10.10.3-0.1-0.50.1-0.2-0.2-0.20.10.1-0.2-0.2-0.2-0.3-0.4-0.60.0-0.00.2-0.20.00.3-0.3-0.4-0.4-0.60.4-0.60.1
Retroperitoneal fat weight0.31.22.4-1.3-0.7-1.00.90.80.8-1.31.11.20.90.80.70.71.41.3-1.5-1.51.3-1.51.2-1.2-1.1-0.71.30.8-0.91.1
Reaction time number correct0.91.62.9-1.7-1.4-1.51.51.51.5-1.61.51.61.51.51.41.41.51.5-1.3-1.31.2-1.41.1-1.1-1.10.30.1-0.10.1-0.0
Reaction time mean minus median1.33.25.42.21.82.0-2.1-2.0-2.02.0-2.0-2.1-2.1-2.1-1.8-1.9-2.3-1.91.72.0-1.71.8-1.81.91.8-0.5-0.6-0.20.2-0.4
Reaction time mean minus median AUC1.12.84.22.01.91.8-1.8-1.7-1.71.8-1.7-1.8-1.8-1.8-1.5-1.5-2.0-1.82.02.0-1.91.7-1.92.02.0-0.2-0.5-0.70.6-0.6
Reaction time num false alarms3.44.87.0-2.4-2.2-2.42.22.22.2-2.52.52.62.22.22.32.32.72.5-2.3-2.62.5-2.52.4-2.4-2.50.11.10.7-0.91.0
Reaction time num false alarms AUC3.45.47.6-2.6-2.5-2.62.32.32.3-2.72.62.72.22.22.32.32.62.8-2.5-2.72.7-2.72.7-2.6-2.7-0.10.81.0-1.11.0
Reaction time trials correct on left0.91.62.9-1.7-1.4-1.51.51.51.5-1.61.51.61.51.51.41.41.51.5-1.3-1.31.2-1.41.1-1.1-1.10.30.1-0.10.1-0.0
Reaction time trials on left0.81.52.7-1.6-1.4-1.51.51.41.4-1.51.41.51.51.41.31.31.51.4-1.3-1.31.1-1.41.1-1.1-1.10.30.2-0.10.00.0
Reaction time mean6.29.816.53.94.13.7-3.6-3.6-3.63.6-3.7-3.5-3.5-3.5-3.2-3.2-3.2-3.43.53.3-3.33.0-3.12.93.1-0.91.4-0.20.20.5
Reaction time mean AUC5.58.815.03.63.93.5-3.3-3.3-3.33.4-3.4-3.3-3.3-3.3-3.0-3.0-3.0-3.33.53.3-3.32.9-3.12.93.0-0.71.2-0.40.40.3
Median of all reaction times6.99.817.93.94.23.7-3.5-3.5-3.53.6-3.7-3.5-3.4-3.4-3.2-3.2-3.0-3.43.73.4-3.42.9-3.22.83.1-0.81.9-0.30.30.6
Reaction time omissions0.40.61.30.80.90.9-0.4-0.5-0.51.0-0.8-0.7-0.5-0.4-0.4-0.5-0.4-1.00.90.9-1.11.0-0.91.01.00.60.5-0.70.5-0.1
Reaction time false alarm rate1.62.13.4-1.5-1.5-1.61.41.41.4-1.71.61.61.31.31.41.41.61.7-1.6-1.81.8-1.61.8-1.8-1.8-0.10.60.8-0.90.8
Reaction time premature initiation rate0.00.00.40.00.00.20.0-0.0-0.00.2-0.1-0.20.0-0.0-0.1-0.1-0.2-0.30.20.2-0.30.3-0.20.10.10.3-0.7-0.0-0.3-0.1
Reaction time premature initiations0.10.30.5-0.7-0.6-0.60.70.70.7-0.50.60.50.70.60.60.60.60.4-0.4-0.40.2-0.30.3-0.3-0.40.4-0.5-0.1-0.2-0.1
Std. dev. reaction times4.48.212.53.53.33.3-3.3-3.2-3.23.3-3.3-3.4-3.4-3.3-3.0-3.1-3.4-3.22.93.1-2.92.9-2.92.82.9-0.80.1-0.20.10.0
Reaction time trials completed0.81.52.7-1.6-1.4-1.51.51.41.4-1.51.41.51.51.41.31.31.51.4-1.3-1.31.1-1.41.1-1.1-1.10.30.2-0.10.00.0
Reaction time trials AUC0.81.42.5-1.6-1.3-1.41.51.41.4-1.41.41.51.41.41.41.31.41.4-1.2-1.21.0-1.31.0-1.0-1.00.40.1-0.20.1-0.0
Run reversals in cocaine runway, females0.50.52.60.00.20.1-0.5-0.5-0.5-0.2-0.10.0-0.5-0.5-0.4-0.40.00.4-0.5-0.50.5-0.70.6-0.8-0.6-1.31.41.6-1.41.5
Run reversals in cocaine runway, males1.01.01.8-1.0-0.8-1.00.80.80.8-1.11.01.10.80.80.80.81.21.2-1.1-1.21.0-1.31.3-1.0-1.2-0.41.00.9-0.81.0
Latency to leave start box in cocaine runway4.04.67.3-2.6-2.5-2.72.52.52.5-2.62.62.62.52.52.62.62.22.4-2.0-2.12.2-2.11.8-1.7-1.80.7-0.9-0.50.3-0.6
Latency to leave start box in cocaine runway, F3.03.56.5-2.1-2.5-2.32.32.32.3-2.12.22.02.32.32.42.31.51.8-1.3-1.31.4-1.31.3-1.3-1.31.3-2.0-0.90.6-1.3
Latency to leave start box in cocaine runway, M2.22.14.3-1.6-0.9-1.51.21.21.2-1.81.51.71.21.21.11.21.81.9-1.7-1.91.9-2.11.4-1.4-1.4-0.81.40.6-0.81.1
Std. dev. time between licks in bursts4.25.78.5-2.9-2.8-2.82.82.92.9-2.72.82.82.82.92.72.72.82.6-2.3-2.42.2-2.22.2-2.3-2.21.0-0.3-0.20.2-0.3
Total sessions with >9 infusions2.22.74.3-2.0-2.1-1.81.61.51.5-2.01.81.71.31.51.61.41.62.0-2.0-1.92.0-1.92.0-1.9-1.9-0.30.01.1-1.00.6
Short access day 1 total inactive lever presses1.41.84.5-1.1-1.2-1.40.60.70.7-1.71.51.50.80.81.11.11.01.8-1.8-1.92.1-2.01.6-1.4-1.6-1.11.01.0-1.01.1
Short access day 10 total inactive lever presses0.00.10.3-0.5-0.3-0.40.50.50.5-0.40.30.30.50.30.10.20.40.3-0.6-0.40.3-0.30.1-0.2-0.30.1-0.10.0-0.0-0.0
Short access day 1 total infusions1.21.63.3-1.4-1.7-1.30.90.80.8-1.51.31.20.60.60.90.90.91.6-1.6-1.61.8-1.61.8-1.7-1.8-0.9-0.01.3-1.20.7
Short access day 10 total infusions0.91.23.8-0.9-0.6-1.01.41.41.4-0.70.91.11.31.61.91.71.20.4-0.6-0.60.4-0.0-0.0-0.30.01.9-0.5-1.11.4-1.1
Short access total infusions0.50.61.5-0.8-0.8-0.80.90.90.9-0.80.80.90.70.81.21.10.90.7-0.8-0.90.9-0.60.7-0.7-0.60.5-0.10.20.0-0.1
Short access day 1 locomotion1.51.83.5-1.5-1.6-1.50.90.90.9-1.71.41.40.80.91.21.11.11.8-1.8-1.71.9-1.91.7-1.4-1.7-1.00.51.2-1.10.9
Short access day 10 total locomotion0.40.71.1-0.9-0.8-0.90.80.80.8-1.01.00.90.70.70.80.81.01.0-1.0-1.00.9-1.00.9-1.0-1.0-0.10.40.2-0.30.3
Short access total locomotion2.02.43.9-1.6-1.6-1.71.31.31.3-1.91.71.71.11.21.51.41.71.9-1.7-1.81.8-2.01.8-1.8-1.8-0.60.91.0-1.01.0
One hour access (0.3 mA shock)0.10.10.5-0.30.0-0.10.50.50.6-0.00.10.30.50.40.30.30.7-0.0-0.1-0.2-0.20.1-0.10.00.00.70.4-0.50.6-0.2
Compulsive drug intake0.91.01.8-0.9-0.9-1.00.90.90.8-1.21.11.10.90.70.70.91.31.2-1.1-1.31.3-1.31.1-1.1-1.3-0.31.10.6-0.70.9
One hour access (shock baseline)0.10.20.50.20.30.3-0.1-0.00.00.4-0.3-0.3-0.00.00.0-0.1-0.2-0.50.30.4-0.60.6-0.40.40.50.6-0.4-0.60.7-0.6
Social response proportion0.60.71.71.31.11.1-1.1-1.0-1.01.0-0.9-0.9-1.0-1.1-0.8-0.8-0.8-0.90.90.8-0.80.8-0.50.40.5-0.30.60.3-0.40.5
Social responses0.10.10.9-0.10.2-0.1-0.1-0.0-0.0-0.20.10.20.00.00.10.00.30.2-0.2-0.30.3-0.40.3-0.4-0.4-0.40.90.4-0.50.7
Social time1.11.43.21.31.31.2-0.9-0.8-0.81.4-1.2-1.2-0.7-0.8-0.7-0.8-1.0-1.51.81.6-1.71.5-1.41.41.40.8-0.4-1.21.3-1.0
Soleus weight0.92.86.7-1.5-1.8-1.50.80.90.9-1.81.61.51.01.01.01.01.22.0-2.5-2.32.6-2.12.1-2.3-2.2-1.20.71.7-1.81.4
Bone: stiffness1.22.08.20.60.70.7-1.7-1.6-1.60.2-0.6-0.6-1.5-1.4-1.5-1.5-0.90.2-0.8-0.60.9-0.90.7-0.8-0.7-2.92.32.5-2.42.4
Tibialis anterior weight3.311.316.6-3.8-3.9-3.93.23.33.3-4.03.93.83.43.43.43.43.54.0-4.1-4.04.1-3.83.8-3.8-3.8-0.10.21.0-1.00.7
Time to tail flick, vehicle, before self-admin0.30.31.0-0.3-0.4-0.40.50.60.6-0.30.40.50.60.80.70.70.60.3-1.0-0.91.0-0.20.4-0.3-0.30.60.1-0.40.4-0.2
Time to tail flick, vehicle, after self-admin0.30.41.00.40.80.6-0.2-0.2-0.20.7-0.5-0.5-0.2-0.1-0.4-0.4-0.2-0.80.60.7-0.90.9-0.90.60.90.7-0.2-0.81.0-0.7
Time to tail flick, test, before self-admin2.12.23.7-1.3-1.3-1.41.11.11.1-1.61.51.61.11.11.31.31.71.8-1.5-1.81.7-1.91.9-1.9-1.8-0.61.61.3-1.11.4
Time to tail flick, test, after self-admin2.12.25.1-1.4-1.8-1.50.80.90.9-1.61.61.41.00.91.01.00.91.8-1.9-1.81.9-1.82.2-2.3-2.1-0.90.31.7-1.51.0
Delta time to tail flick, vehicle, before/after SA0.50.41.40.40.50.6-0.4-0.4-0.40.7-0.5-0.7-0.4-0.4-0.6-0.6-0.7-0.71.01.1-1.20.8-0.90.50.70.3-0.8-0.40.5-0.7
Delta time to tail flick, test, before/after SA0.30.33.50.2-0.30.1-0.3-0.3-0.30.3-0.1-0.5-0.2-0.2-0.3-0.3-1.0-0.3-0.10.4-0.10.5-0.20.20.20.1-1.9-0.10.1-0.9
Tibia length2.87.714.72.92.83.0-3.8-3.8-3.82.4-2.9-3.0-3.8-3.8-3.8-3.8-3.2-1.90.81.3-0.91.1-1.21.31.3-3.61.92.6-2.32.2
Ambulatory time before self-admin2.84.27.22.62.12.4-2.6-2.6-2.62.2-2.3-2.4-2.6-2.7-2.4-2.4-2.6-2.11.92.0-1.71.7-1.61.81.7-1.20.20.4-0.40.3
Ambulatory time after self-admin0.60.71.71.30.91.0-1.1-1.0-1.01.0-0.9-1.0-1.0-1.0-0.9-0.9-1.0-0.90.90.9-0.90.8-0.50.50.5-0.30.30.2-0.10.2
Bone: tissue strength0.00.00.20.20.10.1-0.3-0.3-0.30.1-0.2-0.2-0.2-0.2-0.2-0.2-0.4-0.10.20.3-0.20.1-0.20.30.3-0.2-0.2-0.00.1-0.2
Total heroin consumption1.51.83.21.51.41.3-0.9-0.9-0.91.5-1.4-1.3-0.9-0.9-0.8-0.8-1.1-1.61.71.7-1.71.7-1.71.81.80.9-0.7-1.31.3-1.1
Bone: trabecular number1.11.93.21.61.41.5-1.5-1.5-1.51.5-1.6-1.6-1.5-1.4-1.5-1.5-1.7-1.51.21.4-1.11.5-1.51.81.5-0.2-0.6-0.40.7-0.7
Bone: trabecular spacing0.60.82.6-0.7-0.4-0.60.30.30.3-0.80.70.70.30.30.40.30.91.0-0.6-0.80.6-1.21.1-1.4-1.1-0.91.61.3-1.51.6
Bone: trabecular thickness4.05.08.82.52.22.3-1.9-1.9-1.92.6-2.5-2.5-1.9-1.8-1.9-1.9-2.5-2.72.32.5-2.32.8-2.73.02.70.7-1.4-1.62.0-1.8
Bone: trabecular tissue density0.30.42.80.30.50.4-0.6-0.6-0.60.2-0.3-0.2-0.6-0.6-0.6-0.6-0.1-0.00.10.0-0.1-0.30.3-0.3-0.3-1.01.70.9-0.91.3
Water consumed over 24 hours0.20.30.7-0.4-0.6-0.60.80.70.7-0.40.50.50.80.70.80.80.40.3-0.1-0.20.2-0.1-0.10.20.00.8-0.8-0.60.4-0.6
Number of responses in last shaping day0.00.10.2-0.4-0.4-0.10.50.20.3-0.10.10.10.20.20.10.10.3-0.0-0.1-0.0-0.10.10.2-0.0-0.10.4-0.2-0.30.3-0.3