Hub : Genes

Hibch

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA gene expression Hibch 0.41 0.17 6.2e-15 0.28 0.28 0.28 0.28 1.0e-12 1.1e-12 1.3e-12 1.7e-12
2 OFC mRNA stability Hibch 0.32 0.14 2.6e-05 0.12 0.13 0.12 0.12 7.6e-04 4.6e-04 1.0e-03 7.1e-04
3 NAcc gene expression Hibch 0.08 0.04 6.3e-10 0.05 0.08 0.07 0.07 2.3e-06 1.9e-09 4.7e-09 7.1e-09
4 Adipose isoform ratio NM_001013112.2 0.05 0.03 2.4e-05 0.01 0.02 0.02 0.02 4.3e-02 1.5e-03 1.5e-03 3.6e-03
5 OFC gene expression Hibch 0.32 0.15 5.2e-05 0.14 0.12 0.11 0.13 4.0e-04 9.7e-04 1.5e-03 6.9e-04
6 NAcc mRNA stability Hibch 0.21 0.1 0.0e+00 0.24 0.24 0.24 0.24 7.9e-28 3.1e-27 2.7e-27 8.8e-28
7 Brain mRNA stability Hibch 0.59 0.14 0.0e+00 0.39 0.38 0.38 0.38 7.1e-38 2.8e-37 1.8e-37 8.8e-38
8 LHb gene expression Hibch 0.46 0.16 1.7e-06 0.04 0.09 0.06 0.07 4.3e-02 4.6e-03 1.5e-02 1.1e-02
9 PL mRNA stability Hibch 0.38 0.16 0.0e+00 0.3 0.35 0.34 0.34 1.2e-33 2.6e-39 1.2e-38 1.4e-38
10 RMTg gene expression Hibch 0.16 0.11 1.8e-03 0.03 0.05 0.03 0.04 4.9e-02 1.5e-02 5.5e-02 2.4e-02
11 BLA mRNA stability Hibch 0.32 0.13 0.0e+00 0.25 0.3 0.3 0.32 2.2e-13 2.7e-16 1.8e-16 1.0e-17
12 IL mRNA stability Hibch 0.27 0.15 9.0e-04 0.08 0.09 0.1 0.08 6.0e-03 3.9e-03 1.8e-03 6.0e-03
13 BLA gene expression Hibch 0.11 0.06 2.9e-06 0.11 0.11 0.1 0.11 1.4e-06 2.6e-06 3.5e-06 1.3e-06
14 PL gene expression Hibch 0.2 0.1 0.0e+00 0.23 0.22 0.21 0.23 7.4e-25 9.7e-24 6.6e-23 9.1e-25
15 Brain gene expression Hibch 0.25 0.1 0.0e+00 0.25 0.24 0.24 0.25 5.4e-23 2.0e-22 1.6e-22 7.3e-23
16 Adipose intron excision ratio chr9_48590819_48603695 0.07 0.05 2.2e-07 0.02 0.04 0.04 0.04 1.9e-03 6.0e-05 4.8e-05 7.8e-05
17 Liver isoform ratio NM_001013112.2 0.1 0.08 1.1e-05 0.01 0.02 0.01 0.01 3.7e-02 5.3e-03 7.0e-03 1.2e-02
18 IL gene expression Hibch 0.3 0.16 9.1e-05 0.13 0.16 0.13 0.13 5.2e-04 1.4e-04 4.4e-04 5.2e-04
19 Liver isoform ratio NM_001398668.1 0.16 0.09 5.9e-08 0.03 0.03 0.02 0.02 1.9e-04 3.5e-04 1.1e-03 1.0e-03
20 RMTg intron excision ratio chr9_48604519_48606554 0.17 0.13 8.7e-03 -0.01 0.04 0.02 0.01 4.9e-01 3.8e-02 7.4e-02 2.0e-01
21 RMTg mRNA stability Hibch 0.18 0.13 5.2e-03 0.09 0.05 0.13 0.06 2.2e-03 2.1e-02 3.0e-04 1.3e-02
22 Adipose mRNA stability Hibch 0.2 0.09 0.0e+00 0.09 0.13 0.12 0.12 1.5e-10 3.5e-14 5.2e-13 4.5e-13
23 Adipose gene expression Hibch 0.27 0.1 0.0e+00 0.18 0.2 0.2 0.2 1.1e-19 3.8e-22 1.0e-21 2.3e-21
24 Liver mRNA stability Hibch 0.09 0.05 8.8e-07 0.02 0.03 0.02 0.03 6.1e-03 3.5e-04 1.7e-03 8.1e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density2.23.76.82.02.2-2.3-2.32.0-2.0-2.0-2.42.4-2.42.4-2.0-2.02.02.02.61.5-1.62.01.50.5-0.3-0.1-1.1
Area under the delay curve0.10.10.60.00.1-0.1-0.10.00.1-0.0-0.10.20.00.3-0.4-0.10.10.1-0.10.20.10.1-0.2-0.80.30.2-0.3
BMI with tail4.815.721.0-4.6-4.54.44.4-4.64.54.64.3-4.14.4-4.23.94.3-4.3-4.3-4.4-4.34.3-3.2-3.9-1.02.22.10.1
BMI without tail1.22.53.9-1.9-1.61.61.6-2.01.71.91.5-1.31.7-1.20.91.7-1.7-1.7-1.6-1.71.9-0.5-1.9-1.21.51.4-0.6
Body weight0.10.30.9-0.3-0.40.50.6-0.30.30.20.7-0.70.7-0.70.50.1-0.1-0.1-0.90.2-0.0-0.80.0-0.1-0.5-0.71.0
Weight adjusted by age0.80.93.30.70.4-0.2-0.30.8-0.8-0.8-0.1-0.2-0.4-0.30.6-0.80.80.80.20.9-1.2-0.91.41.7-1.8-1.81.7
Bone surface0.81.43.61.21.0-1.0-1.11.3-1.3-1.2-1.00.7-1.30.6-0.1-1.31.31.21.41.0-1.40.11.61.9-1.4-1.30.7
Bone volume1.93.35.22.01.9-2.0-2.12.1-2.1-2.0-2.01.8-2.21.7-1.2-2.12.12.02.31.7-1.91.22.01.4-1.2-1.10.0
Breakpoint value in progressive ratio session0.70.81.71.01.0-1.0-0.91.0-1.0-1.1-0.91.0-0.71.0-1.3-1.01.01.00.41.2-0.81.10.5-0.7-0.1-0.2-0.2
Number of licking bursts0.70.94.0-0.6-0.1-0.10.0-0.30.30.5-0.10.50.10.9-1.10.4-0.4-0.5-0.0-0.61.01.2-1.3-2.01.81.7-1.8
Context. condit. distance diff. score1.82.28.5-1.3-0.90.70.9-1.31.31.30.7-0.21.10.1-0.61.3-1.3-1.3-1.0-1.31.90.8-2.2-2.92.52.4-1.9
Locomotion velocity, session 10.10.10.5-0.3-0.10.20.2-0.20.20.20.2-0.10.3-0.2-0.00.3-0.3-0.2-0.4-0.10.30.1-0.4-0.70.40.3-0.2
Locomotion distance, session 10.30.30.6-0.6-0.60.70.7-0.50.50.50.7-0.70.7-0.80.80.5-0.5-0.6-0.8-0.40.4-0.7-0.3-0.0-0.1-0.10.5
Locomotion velocity, session 21.61.93.2-1.4-1.61.61.6-1.41.41.41.7-1.81.6-1.71.71.3-1.3-1.4-1.6-1.21.0-1.8-0.70.3-0.2-0.21.0
Locomotion distance, session 20.81.12.8-0.9-1.11.21.1-0.90.90.91.2-1.41.1-1.61.70.9-0.9-1.0-1.1-0.80.5-1.6-0.20.9-0.6-0.51.1
Locomotion velocity, session 30.20.20.4-0.5-0.50.40.4-0.50.50.50.4-0.40.5-0.40.40.6-0.6-0.6-0.5-0.50.5-0.1-0.5-0.30.40.4-0.2
Locomotion distance, session 30.50.51.3-0.8-0.50.40.5-0.70.70.80.4-0.20.5-0.20.20.8-0.8-0.9-0.3-0.91.00.2-1.0-0.81.11.1-0.9
Stereotopy head waving bouts, day 30.40.50.9-0.8-0.80.90.9-0.80.70.80.9-0.90.9-0.80.60.8-0.8-0.8-1.0-0.60.6-0.6-0.6-0.30.10.10.4
Stereotopy head waving duration, day 30.10.10.5-0.2-0.20.20.3-0.20.20.20.3-0.20.3-0.1-0.20.2-0.2-0.2-0.5-0.00.20.0-0.3-0.70.10.00.1
Locomotion velocity, session 70.60.72.8-0.2-0.60.70.6-0.20.20.20.8-1.10.6-1.11.20.2-0.2-0.1-0.6-0.0-0.3-1.40.61.3-1.3-1.31.7
Locomotion distance, session 70.50.62.2-0.3-0.70.80.8-0.30.40.30.9-1.10.8-1.11.00.4-0.4-0.4-0.9-0.1-0.1-1.30.30.6-1.0-1.11.5
Stereotopy head waving bouts, day 70.20.20.60.40.5-0.5-0.50.4-0.4-0.4-0.50.6-0.40.6-0.8-0.40.40.30.30.5-0.20.80.1-0.60.20.2-0.4
Stereotopy head waving duration, day 70.60.71.00.91.0-1.0-1.00.9-0.9-0.9-1.01.0-0.90.9-0.9-0.90.90.90.90.9-0.81.00.6-0.1-0.1-0.2-0.3
Locomotion velocity, session 80.40.41.0-0.7-0.50.40.4-0.70.70.70.3-0.20.4-0.10.10.7-0.7-0.6-0.3-0.80.90.1-0.9-0.71.01.0-0.8
Locomotion distance, session 81.32.03.1-1.6-1.41.31.4-1.61.61.61.3-1.01.4-1.00.81.6-1.6-1.7-1.3-1.61.7-0.5-1.8-1.21.51.4-0.8
Degree of sensitization distance0.80.83.70.60.10.10.00.6-0.5-0.60.2-0.50.0-0.50.5-0.60.60.7-0.20.9-1.1-1.01.21.2-1.8-1.91.9
Degree of sensitization stereotypy0.30.40.90.40.6-0.7-0.70.5-0.5-0.5-0.70.8-0.70.8-0.8-0.40.40.30.70.3-0.20.90.0-0.50.50.5-0.8
Conditioned locomotion0.10.11.20.20.2-0.1-0.10.2-0.2-0.1-0.00.10.10.4-0.7-0.10.10.1-0.30.4-0.10.4-0.1-1.10.20.0-0.0
Cocaine response after cond. corrected0.50.62.90.1-0.30.40.40.1-0.1-0.00.6-0.80.4-0.90.9-0.20.20.1-0.70.5-0.6-1.10.71.0-1.4-1.51.7
Cocaine response after cond. not corrected1.41.55.51.00.6-0.3-0.41.0-1.0-0.9-0.2-0.3-0.4-0.50.6-1.11.11.10.11.4-1.6-0.81.81.8-2.3-2.32.2
Cocaine response before conditioning0.91.12.01.21.0-0.9-1.01.2-1.2-1.1-0.90.7-1.10.4-0.2-1.21.21.21.01.1-1.30.31.41.3-1.2-1.20.7
Saline control response0.20.31.4-0.3-0.1-0.00.0-0.30.30.4-0.10.3-0.00.3-0.30.4-0.4-0.40.2-0.60.70.6-0.8-0.81.11.1-1.2
Bone: connectivity density0.30.41.20.50.7-0.8-0.80.6-0.6-0.6-0.90.8-0.90.9-0.6-0.60.60.61.10.3-0.40.60.50.5-0.10.1-0.5
Bone: cortical apparent density6.07.911.7-3.1-3.23.33.3-3.03.03.03.3-3.33.3-3.33.03.0-3.0-3.0-3.4-2.72.6-2.7-2.3-0.30.70.61.0
Bone: cortical area0.40.52.50.0-0.20.40.30.2-0.2-0.10.4-0.70.3-0.80.9-0.20.20.1-0.40.3-0.5-1.10.81.1-1.4-1.41.6
Bone: cortical porosity1.51.63.71.41.4-1.5-1.61.2-1.2-1.3-1.61.6-1.71.5-1.2-1.31.31.31.90.9-1.01.21.00.6-0.20.0-0.8
Bone: cortical porosity2.02.24.61.71.6-1.7-1.81.5-1.5-1.6-1.81.7-1.91.5-1.1-1.61.61.52.11.2-1.41.11.41.1-0.6-0.4-0.5
Bone: cortical thickness1.22.03.0-1.7-1.71.71.7-1.51.51.51.7-1.71.7-1.71.51.5-1.5-1.5-1.7-1.41.3-1.4-1.1-0.20.30.20.6
Bone: cortical thickness0.10.10.40.10.00.0-0.00.2-0.2-0.20.0-0.2-0.1-0.10.2-0.20.20.20.00.2-0.3-0.30.50.6-0.6-0.60.6
Bone: cortical tissue density5.97.811.5-3.1-3.23.33.3-2.92.93.03.3-3.23.3-3.33.03.0-3.0-3.0-3.4-2.72.6-2.7-2.2-0.30.70.61.1
Condit. Reinf. active minus inactive responses4.14.67.22.52.5-2.4-2.32.5-2.5-2.4-2.32.3-2.22.3-2.4-2.52.52.41.92.7-2.22.01.7-0.6-0.7-0.9-0.2
Condit. Reinf. active-inactive response ratio2.32.54.11.91.9-1.8-1.71.8-1.8-1.8-1.71.7-1.51.7-1.9-1.91.91.71.32.0-1.61.51.2-0.7-0.5-0.6-0.2
Condit. Reinf. active responses3.34.07.12.42.3-2.2-2.12.4-2.4-2.4-2.01.9-1.91.8-1.9-2.42.42.21.62.7-2.31.52.0-0.1-1.3-1.40.4
Condit. Reinf. inactive responses0.20.20.90.30.1-0.0-0.00.4-0.3-0.40.1-0.20.0-0.30.2-0.30.30.2-0.20.6-0.6-0.30.60.3-0.9-0.91.0
Incentive salience index mean3.23.95.42.22.3-2.3-2.22.2-2.2-2.2-2.22.3-2.12.2-2.3-2.22.22.12.02.2-1.82.01.4-0.7-0.3-0.4-0.7
Condit. Reinf. lever presses0.81.12.40.91.1-1.2-1.10.9-0.9-0.9-1.21.4-1.01.4-1.6-0.80.80.81.00.8-0.41.50.1-1.30.70.6-1.2
Condit. Reinf. active minus inactive responses3.34.15.92.42.3-2.2-2.22.3-2.3-2.4-2.12.0-2.21.8-1.7-2.32.32.42.02.4-2.31.52.10.8-1.3-1.30.2
Condit. Reinf. active-inactive response ratio3.03.14.32.02.1-2.1-2.11.9-1.9-1.9-2.02.0-2.02.0-1.9-2.02.02.02.01.9-1.71.61.50.2-0.5-0.5-0.5
Condit. Reinf. active responses0.91.22.11.31.2-1.1-1.11.3-1.3-1.4-1.00.8-1.00.7-0.6-1.31.31.30.81.4-1.40.51.30.7-1.1-1.10.6
Condit. Reinf. inactive responses0.20.20.9-0.1-0.30.30.3-0.10.1-0.10.4-0.50.3-0.70.70.0-0.0-0.0-0.40.1-0.2-0.60.40.8-0.8-0.80.9
Condit. Reinf. lever presses0.10.10.70.40.3-0.3-0.30.3-0.3-0.3-0.30.2-0.4-0.10.2-0.30.30.30.40.3-0.4-0.00.50.8-0.4-0.40.2
Condit. Reinf. lever reinforcers received0.81.12.01.21.0-0.9-0.91.2-1.2-1.3-0.80.6-0.90.5-0.4-1.21.21.30.71.4-1.40.31.40.9-1.2-1.30.9
Conditioned reinforcement - actives0.30.30.70.80.6-0.6-0.60.8-0.8-0.8-0.60.6-0.60.6-0.6-0.40.40.50.70.6-0.70.50.5-0.2-0.3-0.30.0
Conditioned reinforcement - inactives1.01.11.71.11.2-1.1-1.11.2-1.3-1.3-1.10.9-1.10.9-0.7-1.11.11.21.11.2-1.20.51.20.5-0.9-0.80.3
Conditioned locomotion2.12.55.1-1.5-1.81.81.7-1.31.21.21.8-2.11.6-2.12.31.8-1.8-1.5-1.4-1.40.7-2.1-0.31.2-0.9-0.81.7
Patch foraging indifference point 0 sec3.25.28.6-2.6-2.62.52.4-2.62.62.82.3-2.32.1-2.52.92.5-2.5-2.5-1.8-2.92.4-2.3-1.91.01.01.2-0.0
Patch foraging indifference point AUC0.50.63.7-0.6-0.60.60.5-0.40.40.40.5-0.80.3-0.91.50.2-0.2-0.2-0.2-0.60.1-1.40.41.9-0.8-0.60.8
Delay disc. indifference point, 0s delay0.00.00.20.20.2-0.2-0.20.10.1-0.1-0.30.3-0.30.3-0.1-0.10.10.10.4-0.1-0.00.00.00.20.20.3-0.4
Delay disc. indifference point, 16s delay0.50.51.00.70.8-0.8-0.70.8-0.7-0.8-0.80.8-0.70.8-1.0-0.80.80.80.60.9-0.60.90.4-0.50.0-0.1-0.3
Delay disc. indifference point, 2s delay0.00.00.10.10.0-0.1-0.10.00.0-0.0-0.10.0-0.10.0-0.0-0.10.10.10.2-0.1-0.10.10.10.2-0.1-0.0-0.0
Delay disc. indifference point, 24s delay0.30.32.3-0.4-0.00.00.1-0.20.20.20.00.20.30.3-0.60.2-0.2-0.2-0.3-0.10.50.6-0.8-1.51.00.8-0.8
Delay disc. indifference point, 4s delay0.30.30.6-0.5-0.60.60.6-0.60.80.60.6-0.60.6-0.60.50.6-0.6-0.6-0.6-0.60.5-0.7-0.5-0.30.30.30.1
Delay disc. indifference point, 8s delay0.30.30.70.50.6-0.6-0.50.7-0.6-0.7-0.50.5-0.50.6-0.7-0.80.80.80.30.9-0.60.30.5-0.3-0.3-0.40.1
Indifference point function ln k1.01.44.6-1.2-0.70.60.7-1.11.11.20.6-0.20.9-0.1-0.31.1-1.1-1.1-0.8-1.11.50.6-1.8-2.12.01.8-1.5
Indifference point function log k1.01.44.6-1.2-0.70.60.7-1.11.11.20.6-0.20.9-0.1-0.31.1-1.1-1.1-0.8-1.11.50.6-1.8-2.12.01.8-1.5
Patch foraging total patch changes 0 sec3.25.18.6-2.7-2.62.42.3-2.62.62.72.2-2.32.1-2.52.92.5-2.5-2.5-1.7-2.92.4-2.3-1.81.11.01.2-0.1
Patch foraging total patch changes 12 sec0.60.82.5-0.9-0.90.90.8-0.80.80.90.8-1.00.6-1.11.60.7-0.7-0.7-0.5-1.00.6-1.4-0.11.5-0.3-0.20.5
Patch foraging total patch changes 18 sec1.51.94.2-1.7-1.61.51.4-1.51.51.61.3-1.41.2-1.52.01.5-1.5-1.5-0.9-1.91.4-1.5-1.01.20.40.60.0
Patch foraging total patch changes 24 sec0.81.02.3-1.3-1.21.11.0-1.11.11.30.9-1.10.8-1.11.50.9-0.9-1.0-0.6-1.41.0-1.2-0.51.30.10.30.2
Patch foraging total patch changes 6 sec2.74.06.9-2.4-2.42.32.1-2.22.22.42.1-2.11.9-2.12.62.2-2.2-2.2-1.6-2.62.1-2.2-1.51.10.60.80.2
Patch foraging time to switch 0 sec0.81.22.21.31.3-1.2-1.21.3-1.3-1.2-1.21.3-1.11.3-1.5-1.01.01.01.01.3-1.01.30.7-0.7-0.1-0.2-0.4
Patch foraging water rate 0 sec0.81.32.1-1.2-1.31.31.3-1.51.41.21.3-1.31.3-1.41.31.3-1.3-1.3-1.1-1.31.0-1.1-0.80.10.20.20.4
Patch foraging water rate 12 sec0.40.61.7-0.8-0.60.50.6-0.80.90.80.5-0.30.6-0.1-0.10.8-0.8-0.8-0.5-0.91.00.2-1.1-1.31.11.1-0.8
Patch foraging water rate 18 sec0.30.43.2-0.20.1-0.1-0.0-0.20.20.2-0.10.40.10.6-1.10.1-0.1-0.1-0.1-0.10.51.0-0.8-1.81.11.0-1.0
Patch foraging water rate 24 sec0.00.00.20.10.00.10.1-0.00.0-0.10.2-0.20.2-0.3-0.0-0.10.10.0-0.30.4-0.20.10.0-0.4-0.2-0.30.4
Patch foraging water rate 6 sec1.01.52.9-1.5-1.11.01.0-1.41.41.50.9-0.61.1-0.40.11.3-1.3-1.2-1.0-1.41.60.2-1.7-1.41.71.6-1.1
Seeking ratio, delayed vs. immediate footshock2.02.33.31.81.7-1.7-1.71.8-1.8-1.8-1.61.5-1.71.4-1.2-1.51.51.61.61.7-1.80.91.70.6-1.1-1.10.3
Distance traveled before self-admin5.25.68.42.82.4-2.3-2.42.8-2.8-2.9-2.31.9-2.51.8-1.3-2.62.62.52.62.5-2.91.02.91.9-2.3-2.21.0
Distance traveled after self-admin1.11.22.41.61.1-1.0-1.01.4-1.4-1.4-0.90.8-1.00.6-0.5-1.21.21.11.01.3-1.40.21.40.9-1.2-1.20.7
Extensor digitorum longus weight4.919.335.6-4.0-5.05.35.1-4.14.14.15.4-5.95.0-5.95.94.1-4.1-4.1-5.2-3.32.5-6.0-1.62.2-1.7-1.74.3
Bone: elastic displacement0.50.63.0-0.00.4-0.6-0.50.0-0.0-0.0-0.71.0-0.50.9-0.8-0.00.00.00.7-0.30.51.1-0.7-0.91.41.4-1.7
Bone: elastic work1.41.82.41.51.5-1.5-1.51.5-1.5-1.5-1.51.4-1.61.3-1.1-1.51.51.51.51.4-1.41.01.30.7-0.7-0.7-0.1
Bone: endosteal estimation3.47.513.03.22.7-2.5-2.63.1-3.1-3.1-2.41.8-2.81.7-1.1-3.13.13.12.63.1-3.50.63.62.8-3.1-3.01.7
Bone: endosteal perimeter1.43.05.12.01.7-1.5-1.62.0-2.0-2.0-1.41.1-1.61.0-0.8-2.02.02.01.42.1-2.20.42.31.3-2.0-2.01.3
Epididymis fat weight0.40.82.01.00.8-0.6-0.61.0-0.9-1.1-0.50.3-0.50.4-0.5-1.21.21.10.11.4-1.20.01.20.4-1.3-1.41.1
Delta time in closed arm before/after self-admin1.00.92.1-1.0-1.11.11.1-1.01.01.01.1-1.21.0-1.31.40.8-0.8-0.8-1.0-0.80.6-1.2-0.30.8-0.3-0.30.8
Delta time in open arm before/after self-admin3.43.35.22.12.1-2.2-2.22.0-2.0-2.0-2.22.2-2.22.2-1.9-1.81.81.82.31.6-1.61.71.40.2-0.4-0.2-0.9
Diff in mean of infusions in LGA sessions1.51.62.41.41.5-1.5-1.51.4-1.4-1.4-1.51.6-1.41.5-1.6-1.31.31.31.31.4-1.11.50.8-0.3-0.0-0.1-0.7
Delay discount exponential model param0.10.11.10.1-0.10.10.00.0-0.1-0.00.1-0.2-0.1-0.30.50.1-0.1-0.10.1-0.1-0.2-0.20.31.0-0.5-0.40.4
Extinction: sum of active levers before priming1.41.42.31.41.4-1.3-1.31.4-1.4-1.4-1.21.2-1.21.3-1.3-1.31.31.50.91.5-1.31.21.1-0.2-0.6-0.70.1
Active lever presses in extinction session 60.60.61.80.70.8-0.8-0.80.7-0.7-0.7-0.81.0-0.71.1-1.3-0.50.50.70.50.6-0.31.20.0-1.20.50.5-0.8
Bone: final force1.11.85.81.20.7-0.5-0.61.2-1.2-1.2-0.4-0.1-0.7-0.10.4-1.21.21.20.51.4-1.7-0.82.02.1-2.4-2.42.1
Bone: final moment0.71.24.30.80.4-0.2-0.30.9-0.9-0.8-0.1-0.3-0.4-0.30.6-0.90.90.80.31.0-1.3-0.91.61.9-2.1-2.01.9
Food consumed during 24 hour testing period0.60.72.00.70.5-0.5-0.60.8-0.8-0.8-0.40.2-0.70.3-0.0-0.80.80.70.70.8-1.1-0.41.31.4-1.4-1.31.0
Glucose0.81.23.4-1.1-0.70.60.7-1.01.01.00.5-0.20.8-0.2-0.11.0-1.0-0.9-0.8-1.11.40.6-1.7-1.61.81.8-1.5
Heart weight0.30.50.80.80.7-0.7-0.70.7-0.8-0.9-0.70.6-0.80.5-0.4-0.70.70.70.90.7-0.90.20.90.6-0.7-0.60.3
Delay discount hyperbolic model param0.10.10.70.20.1-0.1-0.10.2-0.3-0.2-0.10.0-0.2-0.10.3-0.10.10.10.20.1-0.20.00.30.8-0.4-0.30.2
Intermittent access intake day 1-15 change0.60.61.0-1.0-0.80.70.7-0.90.90.90.7-0.60.8-0.50.50.7-0.7-0.8-0.9-0.81.0-0.5-1.0-0.70.90.8-0.5
Intermittent access intake escalation0.30.30.8-0.6-0.30.30.4-0.50.50.50.3-0.20.5-0.10.00.3-0.3-0.4-0.8-0.30.7-0.1-0.7-0.90.80.7-0.5
Intermittent access intake escalation 20.20.21.0-0.30.0-0.1-0.0-0.20.20.2-0.10.30.10.3-0.40.1-0.1-0.1-0.3-0.10.50.5-0.6-1.00.90.8-0.8
Intermitt. access day 1 inactive lever presses0.10.10.4-0.2-0.40.40.3-0.40.40.40.3-0.30.3-0.30.40.6-0.6-0.60.0-0.60.4-0.3-0.30.20.20.3-0.2
Intermitt. access day 15 inactive lever presses0.70.81.41.11.0-1.0-1.01.1-1.1-1.1-1.01.0-0.91.1-1.2-0.70.70.71.00.8-0.81.20.6-0.4-0.2-0.1-0.3
Intermitt. access escalation Index0.90.82.6-0.9-0.80.90.9-0.90.90.90.9-0.71.1-0.50.00.9-0.9-0.9-1.3-0.71.00.1-1.2-1.60.90.7-0.2
Intermittent access day 1 total infusions0.70.81.90.61.0-1.0-1.00.6-0.7-0.7-1.01.2-0.91.2-1.4-0.60.60.81.00.7-0.41.40.1-0.90.60.5-1.1
Intermittent access day 15 total infusions0.40.42.0-0.40.1-0.2-0.1-0.30.30.3-0.30.5-0.00.6-0.80.1-0.1-0.0-0.1-0.10.60.9-0.8-1.41.31.2-1.3
Intermittent access terminal intake (last 3 days)0.40.51.9-0.8-0.20.10.2-0.60.60.60.00.20.20.3-0.50.5-0.5-0.4-0.3-0.50.90.7-1.0-1.21.41.3-1.2
Intermittent access total infusions0.40.41.30.00.6-0.7-0.60.2-0.3-0.3-0.70.9-0.60.9-1.1-0.20.20.40.60.30.01.1-0.2-0.90.80.8-1.1
Intermittent access day 1 locomotion0.00.00.20.10.2-0.3-0.30.1-0.2-0.2-0.30.3-0.30.3-0.4-0.00.00.20.30.1-0.10.40.1-0.10.00.1-0.2
Intermittent access day 15 total locomotion0.00.00.00.20.1-0.1-0.1-0.0-0.1-0.1-0.00.0-0.1-0.0-0.10.2-0.20.10.10.1-0.2-0.00.1-0.1-0.2-0.20.1
Intermittent access total locomotion0.10.10.4-0.3-0.20.20.2-0.50.40.40.2-0.10.2-0.1-0.10.5-0.5-0.4-0.1-0.40.40.1-0.5-0.60.50.5-0.4
Intermittent access standard deviation0.10.10.4-0.5-0.40.30.3-0.60.60.60.3-0.30.3-0.40.40.2-0.2-0.3-0.3-0.40.4-0.4-0.30.20.30.3-0.1
Left kidney weight0.10.21.00.3-0.00.10.10.1-0.0-0.10.2-0.40.2-0.40.4-0.30.30.3-0.20.4-0.5-0.80.50.6-0.8-0.91.0
Right kidney weight0.41.03.8-0.3-0.81.00.9-0.60.50.51.1-1.40.9-1.41.50.2-0.2-0.2-1.0-0.1-0.1-1.90.41.3-1.3-1.31.8
Cocaine induced anxiety3.54.07.1-2.1-2.32.42.4-2.12.12.12.5-2.52.5-2.52.31.9-1.9-1.9-2.7-1.61.6-2.4-1.4-0.10.1-0.11.3
Post-drug Anxiety1.61.84.0-1.4-1.51.61.6-1.41.41.41.7-1.61.8-1.51.21.3-1.3-1.4-2.0-1.01.2-1.4-1.2-0.80.50.30.6
Baseline Anxiety2.62.85.11.71.9-2.0-1.91.7-1.7-1.7-2.02.1-1.92.2-2.3-1.71.71.61.91.4-1.22.20.8-0.70.30.3-1.3
Tail length3.410.215.03.73.6-3.4-3.43.6-3.8-3.7-3.22.9-3.33.1-3.1-3.63.63.83.03.9-3.62.43.30.7-2.2-2.20.6
Length with tail3.512.720.04.13.8-3.5-3.64.2-4.2-4.2-3.32.8-3.52.9-2.7-4.14.14.33.14.5-4.41.64.21.7-3.3-3.41.7
Length without tail0.61.45.30.80.3-0.1-0.20.9-0.6-0.80.1-0.5-0.2-0.60.8-0.80.80.8-0.01.1-1.4-1.51.71.8-2.3-2.32.3
Times rat made contact with spout0.80.93.7-0.20.2-0.3-0.2-0.30.30.2-0.40.8-0.21.0-1.20.4-0.4-0.40.4-0.50.81.2-1.1-1.81.71.8-1.9
Lifetime Intake0.10.10.5-0.20.3-0.3-0.3-0.1-0.1-0.1-0.30.4-0.20.4-0.50.0-0.00.30.20.10.10.6-0.2-0.60.60.5-0.7
Liver weight, left0.81.38.20.3-0.20.30.20.2-0.1-0.40.3-0.8-0.0-1.01.6-0.30.30.30.10.2-0.9-1.81.42.9-2.0-1.92.0
Liver weight, right0.30.62.50.20.10.0-0.00.4-0.4-0.50.1-0.4-0.1-0.60.9-0.50.50.5-0.20.6-0.7-0.91.01.6-1.3-1.41.4
Locomotor activity0.00.00.1-0.3-0.20.20.2-0.10.10.40.2-0.20.2-0.30.40.1-0.1-0.1-0.2-0.20.2-0.2-0.10.4-0.0-0.00.1
Locomotor testing distance0.10.21.0-0.10.3-0.4-0.40.2-0.20.1-0.50.6-0.50.6-0.4-0.30.30.30.6-0.20.20.7-0.20.10.70.7-1.0
Locomotor testing rearing0.50.83.0-0.9-0.50.40.5-0.70.81.00.30.00.60.1-0.30.7-0.7-0.7-0.6-0.81.20.5-1.4-1.61.71.6-1.4
Locomotion in novel chamber1.82.26.0-1.1-1.51.61.5-1.11.11.11.7-2.01.4-2.12.31.1-1.1-1.0-1.5-0.90.4-2.40.01.6-1.2-1.11.9
Locomotion in novel chamber post-restriction1.11.33.1-0.7-1.21.31.2-0.80.80.81.4-1.61.1-1.61.61.0-1.0-1.0-1.1-0.70.2-1.80.10.7-1.2-1.11.8
Fecal boli incidents, locomotor time 10.00.10.1-0.3-0.20.20.1-0.30.10.30.1-0.10.1-0.10.10.2-0.2-0.2-0.0-0.40.30.2-0.20.40.30.3-0.3
Change in fecal boli incidents, locomotor task0.20.21.4-0.2-0.00.00.1-0.20.20.10.00.10.10.2-0.50.2-0.2-0.2-0.1-0.10.30.4-0.5-1.20.70.6-0.6
Time >=10cm from walls, locomotor time 10.40.42.10.0-0.30.40.30.0-0.00.00.5-0.70.3-0.70.8-0.10.10.1-0.50.3-0.4-1.20.70.9-1.2-1.21.4
Bouts of movement, locomotor time 11.01.11.7-1.2-1.21.11.1-1.21.11.21.1-1.01.1-1.00.91.2-1.2-1.3-1.0-1.21.2-0.7-1.1-0.00.70.7-0.1
Total resting periods, locomotor time 11.41.52.3-1.4-1.41.41.4-1.41.31.41.4-1.31.4-1.41.31.5-1.5-1.5-1.3-1.41.2-1.0-1.10.30.50.50.2
Rest time, locomotor task time 10.60.71.2-0.9-0.80.70.7-0.90.90.90.6-0.40.7-0.50.40.9-0.9-0.9-0.5-1.11.10.1-1.1-0.41.11.1-0.8
Distance moved, locomotor task time 10.20.21.50.50.4-0.3-0.30.5-0.4-0.4-0.20.2-0.10.5-0.7-0.50.50.5-0.20.8-0.40.20.2-1.2-0.2-0.40.3
Vertical activity count, locomotor time 10.00.10.20.10.00.00.10.1-0.0-0.10.1-0.20.1-0.0-0.0-0.20.20.1-0.20.3-0.2-0.40.2-0.4-0.3-0.40.5
Time >=10cm from walls, locomotor time 21.31.42.21.21.4-1.4-1.41.2-1.2-1.2-1.51.5-1.41.4-1.2-1.41.41.31.41.1-0.91.20.7-0.20.10.1-0.8
Bouts of movement, locomotor time 23.13.35.3-2.0-2.12.12.1-2.02.01.92.1-2.02.2-1.81.52.0-2.0-2.0-2.3-1.71.8-1.5-1.7-1.10.80.70.4
Total resting periods, locomotor time 23.13.34.6-2.1-2.12.12.1-2.12.01.92.1-2.02.1-1.81.52.1-2.1-2.1-2.2-1.91.9-1.5-1.8-0.90.90.80.2
Rest time, locomotor task time 21.11.22.6-1.3-1.21.01.0-1.31.31.30.9-0.70.9-0.91.01.3-1.3-1.3-0.6-1.61.4-0.5-1.30.11.11.3-0.8
Distance moved, locomotor task time 20.60.71.71.00.9-0.8-0.71.0-0.9-0.9-0.70.6-0.60.7-0.8-1.11.11.00.41.3-1.00.40.9-0.5-0.7-0.90.5
Vertical activity count, locomotor time 20.10.10.8-0.1-0.10.10.2-0.10.20.20.2-0.10.30.0-0.30.0-0.0-0.1-0.50.10.20.1-0.3-0.90.30.2-0.1
Light reinforcement 13.76.811.2-2.8-3.13.13.0-2.72.72.83.1-3.32.9-3.23.32.5-2.5-2.5-2.9-2.52.0-3.3-1.51.0-0.2-0.21.7
Light reinforcement 20.70.91.8-1.0-1.11.11.1-1.01.01.01.1-1.20.9-1.11.30.9-0.9-0.9-0.8-1.00.7-1.4-0.40.8-0.2-0.10.7
Bone: marrow area3.27.012.33.12.6-2.4-2.53.0-3.0-3.0-2.31.8-2.61.6-1.0-3.03.03.02.53.0-3.40.53.52.7-3.1-2.91.7
Bone: maximum diameter0.10.10.80.1-0.00.10.10.2-0.2-0.10.2-0.30.1-0.30.3-0.20.20.2-0.20.3-0.4-0.50.50.3-0.8-0.80.9
Bone: maximum force2.23.89.72.01.4-1.2-1.42.0-2.0-2.0-1.10.5-1.50.40.1-2.02.02.01.32.0-2.6-0.62.92.9-3.1-3.02.4
Bone: maximum moment1.52.67.41.51.0-0.9-1.01.6-1.6-1.5-0.80.3-1.20.20.3-1.61.61.51.11.6-2.1-0.72.52.7-2.7-2.62.1
Mean time between licks in bursts1.52.15.3-1.2-1.61.71.6-1.21.21.41.7-1.91.4-2.02.31.3-1.3-1.2-1.4-1.20.7-2.2-0.31.5-0.8-0.71.5
Mean num. licks in bursts0.10.10.60.2-0.10.10.1-0.10.1-0.10.1-0.20.0-0.40.50.1-0.1-0.00.1-0.0-0.2-0.60.30.8-0.5-0.50.5
Cd content in liver0.80.92.21.00.8-0.6-0.71.0-1.0-1.0-0.50.3-0.70.3-0.2-1.01.01.00.51.2-1.3-0.11.41.0-1.5-1.51.2
Co content in liver0.60.71.90.50.8-0.8-0.70.5-0.5-0.5-0.81.1-0.61.1-1.3-0.40.40.50.60.4-0.01.4-0.4-1.41.11.0-1.4
Cu content in liver1.92.33.41.61.8-1.8-1.71.7-1.7-1.5-1.71.8-1.61.8-1.8-1.71.71.71.51.7-1.21.80.9-0.6-0.0-0.1-0.7
Fe content in liver2.93.45.22.02.2-2.2-2.12.0-2.0-2.0-2.22.2-2.12.3-2.2-2.02.02.02.01.9-1.62.01.4-0.3-0.3-0.3-0.8
K content in liver1.21.23.6-1.1-1.21.21.0-1.01.01.11.1-1.30.8-1.41.91.0-1.0-1.0-0.6-1.30.7-1.6-0.21.7-0.4-0.20.7
Mg content in liver0.80.81.5-1.1-1.11.00.9-1.01.01.10.9-1.00.8-0.91.21.0-1.0-1.0-0.6-1.20.9-1.0-0.60.60.20.40.1
Mn content in liver0.50.61.7-0.8-0.60.40.4-0.80.80.80.3-0.10.3-0.20.40.8-0.8-0.90.1-1.21.00.1-1.0-0.11.11.3-1.1
Na content in liver0.10.10.3-0.4-0.30.20.2-0.30.30.40.1-0.20.1-0.10.40.3-0.3-0.30.0-0.50.3-0.3-0.20.40.20.3-0.2
Rb content in liver1.11.33.0-0.9-1.21.41.3-0.90.90.81.5-1.61.4-1.61.40.8-0.8-0.9-1.6-0.50.4-1.7-0.20.5-0.8-0.91.6
Se content in liver0.10.10.2-0.3-0.30.30.3-0.30.30.30.3-0.30.2-0.30.50.3-0.3-0.3-0.0-0.30.2-0.4-0.00.3-0.1-0.10.2
Sr content in liver0.20.20.6-0.4-0.30.30.4-0.40.40.40.4-0.20.5-0.30.10.4-0.4-0.4-0.5-0.30.50.1-0.6-0.80.60.5-0.3
Zn content in liver0.70.81.6-1.0-1.01.01.0-0.90.91.01.0-1.01.0-1.31.20.8-0.8-0.9-1.1-0.80.8-0.9-0.70.10.20.10.4
Bone: minimum diameter0.81.65.11.10.6-0.5-0.61.1-1.1-1.0-0.4-0.1-0.7-0.20.6-1.11.11.10.61.1-1.6-0.91.92.2-2.2-2.21.9
Time in familiar zone, hab. session 10.60.51.3-0.8-0.60.60.6-0.80.70.80.6-0.30.7-0.20.00.7-0.7-0.7-0.7-0.70.9-0.0-1.1-1.21.00.9-0.6
Time in novel zone, hab. session 13.53.44.82.02.1-2.2-2.22.0-2.0-2.0-2.22.2-2.22.0-2.0-2.02.02.02.21.8-1.72.01.40.2-0.4-0.4-0.7
Total zone transitions, hab. session 10.40.62.80.50.2-0.1-0.20.5-0.5-0.5-0.0-0.3-0.3-0.50.7-0.50.50.60.30.5-0.9-0.81.11.7-1.5-1.41.3
Total locomotion distance, hab. session 11.62.37.41.30.8-0.6-0.71.3-1.3-1.4-0.5-0.1-0.8-0.20.6-1.41.41.50.71.5-2.0-1.02.32.6-2.7-2.72.3
Locomotion velocity, hab. session 11.01.56.30.5-0.00.20.10.5-0.5-0.60.3-0.8-0.1-0.91.3-0.60.60.70.00.7-1.2-1.61.62.5-2.4-2.32.4
Time in familiar zone, hab. session 20.10.10.3-0.00.1-0.2-0.1-0.00.00.0-0.20.3-0.10.4-0.50.0-0.00.10.1-0.10.20.4-0.2-0.50.50.5-0.5
Time in novel zone, hab. session 20.10.10.5-0.10.0-0.1-0.0-0.10.10.1-0.10.20.00.1-0.30.1-0.1-0.1-0.0-0.10.20.4-0.4-0.70.50.5-0.5
Total zone transitions, hab. session 20.00.10.2-0.2-0.10.10.1-0.20.20.20.10.00.1-0.10.10.2-0.2-0.2-0.1-0.20.30.1-0.4-0.30.40.4-0.4
Total locomotion distance, hab. session 20.40.51.40.70.5-0.4-0.40.8-0.8-0.8-0.30.1-0.4-0.00.1-0.90.90.90.31.0-1.0-0.21.00.8-1.1-1.21.0
Locomotion velocity, hab. session 20.40.51.70.60.4-0.3-0.30.7-0.6-0.7-0.1-0.1-0.3-0.20.3-0.70.70.80.10.9-0.9-0.41.00.9-1.3-1.31.2
Novel to familiar place preference ratio1.51.52.21.31.4-1.4-1.41.3-1.3-1.3-1.51.5-1.51.4-1.3-1.41.41.41.51.1-1.11.30.90.2-0.2-0.2-0.6
Novelty place preference1.11.11.91.01.2-1.3-1.31.0-1.0-1.0-1.31.4-1.31.4-1.3-1.11.11.11.30.8-0.71.30.6-0.20.20.2-0.9
Time in novel zone, NPP test1.31.32.31.11.3-1.4-1.41.1-1.1-1.1-1.41.5-1.31.5-1.4-1.21.21.21.40.9-0.81.50.6-0.30.30.3-1.0
Total zone transitions, NPP test0.40.61.2-0.8-0.80.90.9-0.70.70.70.9-0.91.0-1.10.90.7-0.7-0.7-1.1-0.50.6-0.7-0.7-0.40.20.10.4
Total locomotion distance, NPP test0.30.41.50.40.2-0.2-0.20.5-0.5-0.5-0.1-0.1-0.3-0.30.5-0.50.50.50.30.5-0.7-0.50.91.2-1.1-1.11.0
Locomotion velocity, NPP test0.20.31.7-0.0-0.20.20.20.1-0.1-0.00.3-0.50.1-0.70.9-0.10.10.1-0.00.1-0.4-0.80.61.3-1.0-0.91.0
Intraocular pressure0.30.30.9-0.6-0.40.40.4-0.70.70.60.4-0.20.5-0.40.30.5-0.5-0.6-0.6-0.50.80.1-0.9-0.71.00.9-0.7
Delta distance traveled before/after self-admin0.90.91.7-0.8-1.01.01.1-1.01.01.01.1-0.91.2-0.90.61.2-1.2-1.1-1.3-0.81.0-0.6-1.1-0.90.70.6-0.1
Delta ambulatory time before/after self-admin1.01.12.2-0.9-1.11.11.2-1.21.21.21.2-1.01.3-1.00.71.2-1.2-1.1-1.5-0.91.1-0.7-1.2-0.80.80.7-0.0
Parametrial fat weight0.10.10.8-0.1-0.30.30.4-0.10.20.20.4-0.20.5-0.3-0.00.4-0.4-0.5-0.5-0.20.30.1-0.5-0.90.30.2-0.0
Pavlov. Cond. lever latency2.32.95.3-1.8-1.92.01.9-1.71.71.72.0-2.21.9-2.32.31.7-1.7-1.5-1.9-1.51.2-2.1-0.81.1-0.4-0.31.3
Pavlov. Cond. magazine entry latency2.43.04.21.92.0-2.0-2.01.9-1.9-1.9-2.02.0-1.92.0-2.0-2.02.01.91.81.9-1.61.71.3-0.4-0.3-0.4-0.6
Pavlov. Cond. change in total contacts1.71.93.91.41.6-1.6-1.51.4-1.4-1.4-1.51.6-1.31.8-2.0-1.41.41.31.21.5-1.01.70.6-1.10.20.1-0.8
Pavlov. Cond. index score2.33.05.81.61.9-2.0-1.91.6-1.6-1.6-2.02.3-1.92.4-2.4-1.71.71.61.91.4-1.02.30.6-1.20.60.6-1.6
Pavlov. Cond. latency score2.43.15.61.72.0-2.1-2.01.7-1.7-1.7-2.12.3-1.92.3-2.4-1.71.71.71.91.6-1.22.20.8-1.00.50.4-1.4
Pavlov. Cond. lever contacts1.41.63.71.01.3-1.4-1.30.9-0.9-0.9-1.51.7-1.31.8-1.9-0.90.90.81.30.7-0.31.9-0.0-1.51.11.1-1.7
Pavlov. Cond. magazine entry number4.05.07.8-2.3-2.62.62.5-2.32.42.32.6-2.72.4-2.82.82.4-2.4-2.4-2.3-2.31.8-2.5-1.40.80.00.11.2
Pavlov. Cond. intertrial magazine entries0.10.10.4-0.2-0.20.30.4-0.20.10.20.4-0.40.4-0.50.30.1-0.1-0.0-0.70.10.1-0.3-0.1-0.1-0.2-0.30.5
Pavlov. Cond. lever-magazine prob. diff.1.92.44.61.51.7-1.8-1.71.4-1.5-1.4-1.82.0-1.62.1-2.1-1.51.51.51.61.3-0.92.00.6-1.10.50.5-1.4
Pavlov. Cond. response bias2.12.65.21.51.8-1.9-1.81.5-1.5-1.5-1.92.1-1.72.2-2.3-1.51.51.51.71.3-0.92.20.5-1.30.70.6-1.5
Pavlov. Cond. lever latency0.30.40.7-0.7-0.60.60.7-0.70.70.50.7-0.50.8-0.40.20.6-0.6-0.7-0.8-0.50.7-0.2-0.8-0.80.50.4-0.1
Pavlov. Cond. magazine entry latency0.40.40.80.80.6-0.6-0.70.7-0.7-0.6-0.60.5-0.70.4-0.2-0.70.70.70.70.6-0.80.10.90.9-0.7-0.60.3
Pavlov. Cond. change in total contacts1.01.42.41.31.3-1.3-1.41.3-1.3-1.2-1.41.2-1.51.0-0.7-1.31.31.31.51.1-1.20.81.31.1-0.7-0.6-0.1
Pavlov. Cond. index score0.81.01.81.21.0-1.0-1.01.0-1.0-1.0-1.00.7-1.10.7-0.3-1.11.11.11.21.0-1.20.21.31.3-1.1-0.90.4
Pavlov. Cond. latency score0.81.02.01.20.9-0.9-1.01.0-1.0-0.9-0.90.7-1.10.6-0.3-1.11.11.11.11.0-1.20.11.41.4-1.1-1.00.6
Pavlov. Cond. lever contacts0.60.81.51.10.9-0.9-1.00.9-0.9-0.8-1.00.8-1.10.8-0.5-0.90.90.91.20.7-0.90.41.01.0-0.7-0.50.0
Pavlov. Cond. magazine entry number0.81.01.8-1.1-1.11.11.2-1.01.01.01.1-1.01.3-1.00.71.1-1.1-1.1-1.3-0.91.1-0.5-1.1-1.00.70.6-0.0
Pavlov. Cond. intertrial magazine entries0.81.11.7-1.2-1.11.11.2-1.11.11.01.2-1.01.3-0.90.61.2-1.2-1.2-1.3-1.01.1-0.6-1.2-0.90.70.6-0.1
Pavlov. Cond. lever-magazine prob. diff.0.50.61.80.90.7-0.7-0.70.8-0.8-0.7-0.70.5-0.80.3-0.0-0.80.80.80.90.7-1.0-0.01.11.4-1.0-0.90.5
Pavlov. Cond. response bias1.11.52.91.41.2-1.2-1.31.3-1.3-1.2-1.21.0-1.40.8-0.4-1.31.31.31.51.1-1.40.31.61.7-1.3-1.10.5
Time in closed arm before self-admin2.52.84.31.81.9-1.9-1.91.9-1.9-1.9-1.91.8-2.01.7-1.4-1.81.81.92.11.6-1.71.31.60.9-0.7-0.7-0.3
Time in closed arm after self-admin0.30.31.30.40.4-0.3-0.40.5-0.5-0.5-0.30.1-0.50.00.3-0.50.50.60.40.5-0.6-0.20.81.1-0.8-0.70.5
Time in open arm before self-admin2.42.65.6-1.8-1.81.92.0-1.81.81.72.0-1.92.1-1.81.31.6-1.6-1.7-2.4-1.21.5-1.3-1.5-1.10.60.30.7
Time in open arm after self-admin2.22.53.41.81.8-1.8-1.81.8-1.8-1.8-1.71.7-1.71.8-1.7-1.81.81.61.71.7-1.51.51.3-0.1-0.6-0.6-0.3
Bone: periosteal estimation1.94.08.02.21.7-1.6-1.72.2-2.2-2.2-1.51.0-1.80.8-0.4-2.32.32.21.62.3-2.6-0.02.82.4-2.7-2.71.9
Bone: periosteal perimeter0.81.32.41.31.1-0.9-1.01.4-1.4-1.3-0.80.6-1.00.5-0.3-1.41.41.30.81.4-1.50.21.51.0-1.5-1.51.1
Bone: post-yield work1.31.83.51.51.2-1.1-1.11.5-1.5-1.5-1.00.7-1.20.6-0.3-1.41.41.51.11.5-1.80.01.91.5-1.8-1.81.2
Progressive ratio test 1 active lever presses0.00.00.2-0.2-0.20.20.2-0.30.20.30.2-0.30.2-0.30.4-0.00.0-0.0-0.2-0.10.1-0.4-0.00.3-0.1-0.10.2
Progressive ratio test 1 breakpoint0.10.10.3-0.3-0.30.30.2-0.40.30.30.3-0.30.2-0.40.50.1-0.1-0.1-0.2-0.20.1-0.6-0.00.5-0.1-0.10.2
Progressive ratio test 1 inactive lever presses0.10.10.5-0.0-0.10.10.1-0.10.00.00.1-0.20.1-0.40.60.2-0.2-0.10.0-0.0-0.1-0.70.20.5-0.3-0.30.4
Progressive ratio test 2 active lever presses0.20.20.50.30.6-0.6-0.50.3-0.4-0.4-0.50.6-0.40.6-0.7-0.50.50.60.30.6-0.30.60.1-0.60.30.1-0.4
Progressive ratio test 2 breakpoint0.10.21.0-0.10.3-0.3-0.2-0.1-0.0-0.0-0.30.4-0.10.5-0.6-0.10.10.20.00.20.20.5-0.4-1.00.70.6-0.7
Progressive ratio test 2 inactive lever presses0.20.20.40.50.6-0.6-0.50.5-0.5-0.5-0.60.6-0.50.5-0.4-0.50.50.40.50.5-0.40.20.2-0.10.10.1-0.3
Incentive Sensitization - Responses0.30.40.70.60.7-0.7-0.60.7-0.7-0.7-0.60.6-0.50.7-0.7-0.60.60.70.40.8-0.60.60.4-0.4-0.1-0.2-0.1
Incentive Sensitization - Breakpoint0.20.20.40.40.5-0.5-0.50.5-0.5-0.5-0.50.5-0.40.6-0.6-0.40.40.50.30.6-0.40.50.2-0.5-0.0-0.1-0.1
Sum of active levers in priming session hrs 5-62.01.93.41.81.6-1.5-1.51.6-1.6-1.6-1.41.4-1.31.4-1.6-1.61.61.80.91.8-1.51.21.1-0.3-0.6-0.70.0
Progressive ratio0.20.21.1-0.2-0.40.50.6-0.20.20.20.6-0.70.7-0.50.30.2-0.2-0.2-1.10.2-0.0-0.6-0.0-0.4-0.4-0.60.9
Food seeking constrained by brief footshock0.30.41.70.1-0.20.40.40.0-0.0-0.00.5-0.70.4-0.70.8-0.20.20.2-0.70.3-0.4-1.10.51.0-1.0-1.11.3
Seeking ratio, punishment vs. effort0.10.21.70.20.1-0.1-0.20.2-0.2-0.2-0.2-0.0-0.3-0.20.5-0.20.20.20.50.0-0.3-0.40.51.3-0.5-0.40.3
Retroperitoneal fat weight0.10.52.3-0.3-0.50.60.6-0.10.10.20.8-1.00.7-0.80.60.0-0.00.0-1.10.2-0.2-1.00.40.4-1.0-1.21.5
Reaction time number correct1.31.82.7-1.5-1.61.61.6-1.61.61.51.6-1.61.6-1.41.21.4-1.4-1.4-1.6-1.31.3-1.3-1.1-0.40.40.30.5
Reaction time mean minus median2.43.25.22.22.0-2.0-2.11.9-1.9-1.9-2.12.0-2.12.0-1.8-1.81.81.82.31.6-1.81.61.60.7-0.7-0.5-0.5
Reaction time mean minus median AUC1.82.33.61.91.7-1.7-1.71.6-1.6-1.6-1.81.8-1.81.8-1.8-1.51.51.51.81.3-1.41.71.20.1-0.4-0.3-0.6
Reaction time num false alarms3.44.67.9-2.2-2.52.62.7-2.12.12.12.7-2.82.7-2.62.32.2-2.2-2.2-2.8-1.81.7-2.3-1.4-0.2-0.1-0.21.5
Reaction time num false alarms AUC3.64.98.6-2.2-2.62.72.7-2.12.12.22.8-2.92.7-2.82.62.2-2.2-2.2-2.7-1.91.6-2.6-1.20.3-0.4-0.41.8
Reaction time trials correct on left1.31.82.7-1.5-1.61.61.6-1.61.61.51.6-1.61.6-1.41.21.4-1.4-1.4-1.6-1.31.3-1.3-1.1-0.40.40.30.5
Reaction time trials on left1.21.72.5-1.5-1.51.51.6-1.61.51.51.6-1.51.6-1.31.21.3-1.3-1.3-1.6-1.21.2-1.3-1.1-0.30.40.30.5
Reaction time mean6.69.212.63.63.6-3.5-3.43.5-3.5-3.4-3.43.4-3.33.3-3.4-3.23.23.33.13.4-3.13.12.5-0.2-1.1-1.1-0.6
Reaction time mean AUC5.97.910.93.33.3-3.3-3.23.2-3.2-3.1-3.13.2-3.03.1-3.2-3.03.03.02.83.2-2.83.02.2-0.3-0.8-0.9-0.7
Median of all reaction times6.28.611.93.43.5-3.4-3.33.4-3.4-3.3-3.23.3-3.13.1-3.4-3.13.13.22.83.5-2.93.12.3-0.6-0.9-1.0-0.6
Reaction time omissions0.50.61.50.70.9-0.9-0.80.6-0.6-0.7-0.91.1-0.71.1-1.2-0.60.60.60.60.7-0.21.1-0.1-1.10.80.6-1.0
Reaction time false alarm rate1.31.93.4-1.3-1.61.71.6-1.11.11.31.7-1.81.6-1.81.71.4-1.4-1.4-1.7-1.10.9-1.6-0.70.3-0.3-0.41.2
Reaction time premature initiation rate0.00.00.00.00.1-0.1-0.10.1-0.10.0-0.10.1-0.1-0.00.0-0.10.10.1-0.00.10.00.2-0.10.00.20.2-0.2
Reaction time premature initiations0.30.40.7-0.8-0.70.70.7-0.80.70.80.7-0.70.7-0.60.60.6-0.6-0.6-0.8-0.60.7-0.5-0.7-0.30.40.30.0
Std. dev. reaction times5.98.311.93.43.3-3.3-3.33.2-3.2-3.2-3.33.2-3.33.1-2.9-3.03.03.03.42.9-2.92.72.50.7-1.1-1.0-0.7
Reaction time trials completed1.21.72.5-1.5-1.51.51.6-1.61.51.51.6-1.51.6-1.31.21.3-1.3-1.3-1.6-1.21.2-1.3-1.1-0.30.40.30.5
Reaction time trials AUC1.21.72.4-1.5-1.51.51.5-1.51.51.51.5-1.51.5-1.21.11.3-1.3-1.4-1.5-1.31.3-1.2-1.1-0.40.40.40.4
Run reversals in cocaine runway, females0.50.41.7-0.2-0.40.50.5-0.10.10.10.6-0.80.5-1.01.00.1-0.1-0.1-0.60.1-0.2-1.00.41.0-1.0-1.01.3
Run reversals in cocaine runway, males0.90.92.3-0.8-1.01.11.1-0.80.80.81.2-1.31.1-1.31.30.8-0.8-0.8-1.3-0.50.4-1.5-0.20.4-0.5-0.61.2
Latency to leave start box in cocaine runway5.35.77.9-2.7-2.82.82.7-2.72.72.72.7-2.62.6-2.52.22.8-2.8-2.8-2.4-2.82.5-1.8-2.1-0.40.91.00.3
Latency to leave start box in cocaine runway, F3.33.66.6-2.2-2.22.01.9-2.22.22.21.8-1.71.8-1.71.82.3-2.3-2.3-1.4-2.62.2-1.2-1.8-0.01.21.4-0.5
Latency to leave start box in cocaine runway, M2.12.04.2-1.3-1.61.81.8-1.31.31.31.9-2.01.8-1.81.41.3-1.3-1.3-2.0-0.90.8-1.5-0.5-0.0-0.6-0.71.7
Std. dev. time between licks in bursts4.95.98.1-2.8-2.82.72.8-2.72.72.82.7-2.62.7-2.52.42.6-2.6-2.6-2.7-2.62.5-2.2-2.2-0.51.11.10.3
Total sessions with >9 infusions1.11.34.0-0.8-0.91.11.0-0.70.60.51.1-1.40.9-1.61.80.7-0.7-0.5-1.1-0.30.0-2.00.41.6-1.3-1.31.8
Short access day 1 total inactive lever presses0.20.20.80.0-0.40.50.4-0.20.20.20.5-0.60.3-0.70.80.4-0.4-0.4-0.0-0.3-0.2-0.60.30.8-0.8-0.70.9
Short access day 10 total inactive lever presses0.40.40.90.90.7-0.6-0.70.9-0.9-0.8-0.60.5-0.70.5-0.4-0.70.70.60.70.8-0.80.20.80.4-0.6-0.60.3
Short access day 1 total infusions0.30.32.7-0.2-0.20.20.1-0.1-0.0-0.00.1-0.4-0.1-0.61.0-0.00.00.10.2-0.2-0.2-0.90.61.6-0.8-0.70.7
Short access day 10 total infusions0.70.73.3-0.30.4-0.5-0.4-0.20.00.0-0.50.8-0.20.9-1.30.2-0.20.10.30.00.51.4-0.9-1.81.51.4-1.6
Short access total infusions0.10.10.3-0.6-0.20.20.2-0.40.30.30.2-0.20.2-0.20.20.3-0.3-0.1-0.3-0.20.3-0.2-0.2-0.00.20.1-0.0
Short access day 1 locomotion0.30.31.3-0.3-0.40.40.4-0.30.20.20.4-0.60.2-0.70.90.4-0.4-0.2-0.1-0.2-0.2-0.80.51.2-0.9-0.81.0
Short access day 10 total locomotion0.20.30.80.50.3-0.2-0.20.5-0.5-0.5-0.1-0.0-0.2-0.10.1-0.40.40.50.10.6-0.7-0.30.70.7-0.9-0.90.8
Short access total locomotion0.70.72.7-0.3-0.70.80.7-0.30.20.20.8-1.10.6-1.11.20.6-0.6-0.4-0.6-0.2-0.3-1.30.61.2-1.4-1.31.7
One hour access (0.3 mA shock)0.50.62.20.30.7-0.7-0.60.4-0.4-0.4-0.70.9-0.51.1-1.4-0.50.50.50.30.5-0.01.4-0.3-1.50.90.7-1.1
Compulsive drug intake0.10.10.6-0.3-0.30.30.4-0.20.30.30.3-0.20.4-0.10.00.2-0.2-0.4-0.6-0.20.5-0.0-0.6-0.80.50.4-0.3
One hour access (shock baseline)0.50.61.60.50.8-0.8-0.80.4-0.5-0.5-0.91.0-0.71.1-1.2-0.50.50.70.70.6-0.31.30.0-0.90.60.5-0.9
Social response proportion0.60.61.31.11.0-0.9-0.90.9-0.9-1.1-0.80.9-0.80.6-0.6-0.80.80.70.81.0-0.90.80.6-0.1-0.3-0.3-0.1
Social responses0.00.10.20.1-0.10.20.2-0.20.2-0.10.2-0.20.2-0.40.20.1-0.1-0.1-0.20.1-0.2-0.20.1-0.0-0.3-0.40.5
Social time0.70.91.71.01.1-1.1-1.00.7-0.7-0.9-1.11.3-1.01.2-1.3-0.70.70.71.00.7-0.41.30.1-0.90.60.6-1.1
Soleus weight0.61.85.0-0.6-1.21.41.2-0.80.80.71.4-1.81.1-1.92.10.8-0.8-0.8-1.1-0.6-0.0-2.20.52.0-1.6-1.52.2
Bone: stiffness2.03.19.31.61.1-0.8-1.01.7-1.7-1.7-0.70.1-1.1-0.00.4-1.71.71.70.81.9-2.3-0.82.62.7-3.0-3.02.6
Tibialis anterior weight2.79.414.5-3.1-3.63.73.6-3.23.23.23.7-3.83.5-3.73.73.2-3.2-3.2-3.4-2.92.4-3.6-1.90.8-0.1-0.11.9
Time to tail flick, vehicle, before self-admin0.60.61.0-0.9-0.80.80.8-0.90.90.90.7-0.60.8-0.60.51.0-1.0-1.0-0.8-0.90.9-0.5-0.9-0.70.70.7-0.3
Time to tail flick, vehicle, after self-admin0.20.20.50.40.5-0.5-0.50.4-0.4-0.4-0.50.5-0.40.5-0.6-0.60.60.70.20.5-0.30.60.2-0.20.10.1-0.3
Time to tail flick, test, before self-admin1.31.32.3-0.9-1.21.41.4-1.01.01.01.4-1.41.4-1.51.31.2-1.2-1.1-1.5-0.70.7-1.4-0.6-0.0-0.2-0.31.0
Time to tail flick, test, after self-admin1.92.04.1-1.4-1.61.61.6-1.41.41.41.6-1.71.5-1.92.01.5-1.5-1.4-1.3-1.41.0-1.9-0.81.0-0.1-0.00.8
Delta time to tail flick, vehicle, before/after SA0.90.81.61.01.0-1.0-1.01.0-1.0-1.0-0.90.8-1.00.8-0.7-1.21.21.30.81.1-1.00.61.00.7-0.6-0.60.1
Delta time to tail flick, test, before/after SA0.10.10.8-0.4-0.20.0-0.0-0.30.30.2-0.10.1-0.2-0.00.40.2-0.2-0.20.6-0.70.4-0.0-0.10.90.30.5-0.6
Tibia length4.011.119.63.83.2-3.0-3.23.8-3.8-3.8-2.92.2-3.32.0-1.3-3.83.83.83.03.8-4.20.84.43.4-3.9-3.82.2
Ambulatory time before self-admin4.14.26.22.42.1-2.0-2.12.4-2.4-2.5-2.01.7-2.21.6-1.3-2.32.32.22.22.2-2.51.02.51.4-2.0-1.90.8
Ambulatory time after self-admin0.20.20.70.60.2-0.2-0.20.5-0.5-0.5-0.1-0.0-0.2-0.20.3-0.40.40.30.10.5-0.6-0.40.70.8-0.8-0.80.8
Bone: tissue strength0.10.10.40.0-0.10.10.10.0-0.00.00.1-0.20.0-0.20.40.1-0.1-0.00.1-0.1-0.2-0.30.30.6-0.4-0.40.4
Total heroin consumption0.70.91.60.91.0-1.1-1.10.9-0.9-0.9-1.21.3-1.11.2-1.2-0.70.70.91.20.6-0.51.30.3-0.20.40.4-1.0
Bone: trabecular number1.11.72.91.41.5-1.5-1.51.5-1.5-1.4-1.51.4-1.61.5-1.2-1.41.41.41.71.2-1.31.11.20.6-0.6-0.4-0.3
Bone: trabecular spacing0.40.51.4-0.4-0.70.80.8-0.50.50.40.9-1.00.9-1.00.60.5-0.5-0.5-1.2-0.00.1-0.9-0.1-0.2-0.5-0.71.1
Bone: trabecular thickness3.34.06.81.92.3-2.4-2.42.0-2.0-2.0-2.52.6-2.52.6-2.3-2.02.02.02.61.5-1.42.41.1-0.10.30.4-1.6
Bone: trabecular tissue density0.20.30.90.60.4-0.3-0.20.6-0.6-0.6-0.10.0-0.2-0.0-0.1-0.50.50.6-0.10.8-0.7-0.10.70.3-0.8-0.90.9
Water consumed over 24 hours0.70.91.3-1.1-1.00.90.9-1.11.11.00.9-0.70.9-0.50.31.1-1.1-1.1-0.8-1.11.1-0.5-1.1-0.90.90.9-0.4
Number of responses in last shaping day0.20.20.4-0.5-0.40.40.4-0.60.50.50.4-0.40.4-0.50.60.3-0.3-0.3-0.5-0.40.4-0.6-0.30.30.10.10.1