Hells

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 NAcc intron excision ratio chr1_236702274_236707071 0.02 0.01 9.0e-03 0.01 0.01 0.01 0.01 1.2e-02 1.4e-02 4.4e-02 1.9e-02
2 Liver isoform ratio XM_008760366.3 0.05 0.03 2.3e-05 0.03 0.03 0.02 0.02 1.9e-04 4.6e-04 1.7e-03 1.0e-03
3 LHb alternative polyA XM_017589048.2 0.14 0.09 2.5e-03 0.07 0.09 0.09 0.06 9.7e-03 3.7e-03 4.2e-03 1.2e-02
4 LHb alternative polyA NM_001106371.1 0.14 0.09 3.2e-03 0.07 0.09 0.08 0.06 1.1e-02 4.4e-03 5.6e-03 1.4e-02
5 Liver isoform ratio NM_001106371.1 0.04 0.03 1.0e-04 0.03 0.02 0.02 0.02 3.8e-04 1.7e-03 6.6e-03 2.4e-03
6 LHb alternative polyA XM_017589048.2 0.15 0.11 3.6e-03 0.1 0.09 0.07 0.09 3.0e-03 3.7e-03 7.5e-03 4.1e-03
7 NAcc gene expression Hells 0.02 0.02 6.9e-03 0.01 0.01 0.01 0.01 3.2e-02 9.8e-03 8.3e-03 2.6e-02
8 Liver alternative polyA XM_017589048.2 0.05 0.03 2.4e-04 0.02 0.03 0.03 0.03 1.4e-03 3.0e-04 4.7e-04 5.7e-04
9 Liver alternative polyA XM_008760366.3 0.04 0.03 3.7e-04 0.02 0.03 0.02 0.02 5.0e-03 4.2e-04 9.1e-04 2.4e-03
10 Liver alternative polyA NM_001106371.1 0.04 0.03 3.0e-04 0.01 0.03 0.02 0.02 9.4e-03 3.7e-04 9.0e-04 2.2e-03
11 Liver alternative polyA NM_001106371.1 0.04 0.03 4.6e-04 0.01 0.03 0.02 0.02 2.0e-02 8.5e-04 1.1e-03 1.9e-03
12 Brain gene expression Hells 0.03 0.02 8.1e-03 0 0.01 0 0 1.8e-01 5.9e-02 1.4e-01 2.5e-01
13 PL gene expression Hells 0.24 0.13 9.4e-06 0.03 0.05 0.04 0.03 1.5e-04 8.5e-06 3.0e-05 1.4e-04
14 pVTA gene expression Hells 0.06 0.05 8.3e-03 0.02 0.04 0.01 0.02 4.3e-02 5.5e-03 1.4e-01 4.9e-02
15 LHb gene expression Hells 0.29 0.13 1.3e-06 0.2 0.24 0.22 0.23 1.9e-05 1.7e-06 5.6e-06 2.8e-06
16 Adipose gene expression Hells 0.05 0.04 1.2e-03 0.02 0.01 0.01 0.01 1.8e-03 4.5e-02 1.1e-02 1.3e-02
17 LHb alternative polyA XM_008760366.3 0.23 0.13 4.3e-03 0.06 0.04 0.02 0.05 1.3e-02 3.2e-02 8.9e-02 2.2e-02
18 Liver gene expression Hells 0.08 0.08 2.5e-05 0.04 0.04 0.06 0.04 3.9e-05 2.1e-05 1.3e-07 8.5e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18
Bone: apparent density2.13.66.0-2.2-2.2-1.81.82.22.4-1.92.42.3-2.3-2.31.30.91.31.2-1.0-1.7-1.6
Area under the delay curve1.01.02.70.90.71.2-1.2-0.6-0.71.5-0.2-0.20.20.2-1.3-1.6-1.4-1.31.5-0.60.2
BMI with tail1.03.45.6-2.4-2.0-2.22.21.71.7-1.72.02.1-2.1-2.01.91.51.91.8-1.5-1.30.2
BMI without tail1.32.74.5-1.8-1.5-2.12.11.21.4-1.91.31.3-1.3-1.32.11.42.12.1-1.9-0.30.9
Body weight0.41.83.4-1.5-1.2-1.81.80.91.0-1.50.90.9-0.9-0.81.81.71.81.8-1.70.10.2
Weight adjusted by age0.30.40.8-0.7-0.1-0.70.80.30.6-0.50.50.6-0.5-0.50.80.90.70.8-0.6-0.10.7
Bone surface2.54.47.0-2.5-2.6-2.22.22.62.4-2.12.32.3-2.3-2.31.81.71.81.8-1.6-1.5-1.0
Bone volume2.13.54.9-2.2-2.1-2.22.12.22.2-2.21.91.8-1.8-1.91.91.41.91.9-1.7-0.9-0.8
Breakpoint value in progressive ratio session0.70.71.60.80.41.1-1.1-0.3-0.51.1-0.4-0.40.40.4-1.3-1.1-1.2-1.31.2-0.2-0.6
Number of licking bursts1.41.73.41.21.61.5-1.5-1.3-0.81.6-0.5-0.40.40.4-1.7-1.7-1.7-1.61.8-0.50.8
Context. condit. distance diff. score0.60.82.2-0.8-1.1-0.80.81.31.5-0.71.21.0-1.1-1.10.5-0.20.60.5-0.4-0.7-0.3
Locomotion velocity, session 13.53.79.52.01.92.3-2.3-1.9-1.42.3-0.9-0.80.80.8-2.4-3.1-2.4-2.42.7-0.41.3
Locomotion distance, session 11.11.53.51.21.41.4-1.4-1.3-0.91.4-0.6-0.60.60.6-1.4-1.9-1.4-1.41.6-0.20.8
Locomotion velocity, session 21.61.96.9-0.9-1.00.3-0.30.90.90.41.71.8-1.8-1.8-1.1-0.9-1.1-1.31.2-2.6-1.9
Locomotion distance, session 20.40.52.1-0.3-0.00.4-0.40.10.40.50.80.8-0.8-0.8-0.8-0.8-0.8-0.91.0-1.5-0.5
Locomotion velocity, session 30.10.10.4-0.3-0.2-0.10.10.20.2-0.20.40.3-0.4-0.4-0.1-0.5-0.0-0.20.0-0.5-0.7
Locomotion distance, session 30.20.20.70.20.2-0.10.1-0.00.2-0.5-0.3-0.60.50.40.2-0.40.40.2-0.50.9-0.7
Stereotopy head waving bouts, day 30.20.21.30.3-0.10.3-0.30.20.30.30.20.1-0.2-0.2-0.5-1.1-0.4-0.40.4-0.2-1.0
Stereotopy head waving duration, day 30.30.42.00.0-0.40.2-0.20.40.60.30.60.6-0.6-0.7-0.5-1.4-0.4-0.50.7-0.8-0.6
Locomotion velocity, session 71.41.53.6-1.2-1.4-1.41.41.61.9-1.41.31.1-1.2-1.31.1-0.31.31.1-1.0-0.5-0.6
Locomotion distance, session 71.31.72.7-1.4-1.3-1.61.61.61.6-1.51.21.0-1.1-1.11.40.71.51.4-1.4-0.3-0.6
Stereotopy head waving bouts, day 71.82.07.41.40.81.7-1.7-0.5-0.11.5-0.2-0.30.30.2-2.0-2.7-1.9-2.02.1-0.6-0.8
Stereotopy head waving duration, day 70.70.94.41.20.61.1-1.1-0.30.00.8-0.3-0.40.40.3-1.2-2.1-1.1-1.21.30.0-0.1
Locomotion velocity, session 80.30.41.2-0.5-0.6-0.10.10.40.7-0.00.90.8-0.8-0.9-0.2-0.7-0.2-0.30.3-1.1-0.7
Locomotion distance, session 81.01.44.3-1.2-1.2-0.40.41.21.4-0.31.81.8-1.8-1.8-0.2-0.4-0.2-0.30.4-2.1-1.1
Degree of sensitization distance0.60.61.8-0.8-0.9-0.50.41.00.9-0.11.21.2-1.2-1.20.10.10.10.10.2-1.3-0.0
Degree of sensitization stereotypy1.61.83.71.41.11.7-1.7-0.9-0.51.5-0.6-0.60.60.5-1.9-1.9-1.9-1.91.9-0.3-0.6
Conditioned locomotion0.70.82.3-0.3-0.4-1.01.00.30.3-1.1-0.2-0.30.30.31.40.81.31.4-1.31.11.5
Cocaine response after cond. corrected0.10.10.3-0.10.10.1-0.10.10.00.30.30.3-0.3-0.3-0.3-0.3-0.3-0.30.3-0.60.3
Cocaine response after cond. not corrected0.20.20.7-0.10.10.3-0.40.1-0.00.50.40.4-0.4-0.4-0.6-0.4-0.6-0.70.6-0.9-0.5
Cocaine response before conditioning0.50.61.40.40.30.9-0.9-0.4-0.40.8-0.0-0.10.10.0-1.1-1.0-1.1-1.21.0-0.6-1.1
Saline control response2.73.65.32.22.02.3-2.3-2.1-2.22.0-1.9-1.81.81.8-2.1-1.0-2.2-2.11.80.80.6
Bone: connectivity density4.06.49.2-3.0-3.0-2.62.63.03.0-2.52.92.9-2.9-2.82.11.92.01.9-1.6-2.0-1.9
Bone: cortical apparent density1.21.62.71.61.31.6-1.6-1.2-1.01.5-0.9-0.80.80.8-1.6-1.5-1.6-1.51.60.20.0
Bone: cortical area0.40.71.8-0.5-0.5-0.90.90.60.5-1.1-0.1-0.20.20.21.10.91.21.2-1.40.9-0.2
Bone: cortical porosity1.31.45.1-1.0-0.9-0.30.30.91.20.21.81.8-1.8-1.8-0.3-1.2-0.3-0.40.8-2.30.6
Bone: cortical porosity1.41.64.9-1.3-1.2-0.60.61.21.5-0.21.91.9-1.9-1.9-0.0-0.90.0-0.10.5-2.20.3
Bone: cortical thickness1.72.84.32.02.11.7-1.7-1.9-1.81.4-2.0-2.12.02.0-1.4-1.3-1.3-1.31.11.50.9
Bone: cortical thickness3.03.55.12.02.12.2-2.2-2.0-1.92.1-1.5-1.51.51.5-2.1-2.2-2.1-2.12.00.40.9
Bone: cortical tissue density1.11.42.71.51.21.5-1.5-1.0-0.91.4-0.7-0.70.70.7-1.5-1.4-1.5-1.51.60.00.0
Condit. Reinf. active minus inactive responses0.30.31.20.50.50.6-0.6-0.5-0.30.5-0.2-0.30.30.2-0.7-1.1-0.6-0.60.6-0.00.6
Condit. Reinf. active-inactive response ratio0.10.10.30.40.40.4-0.3-0.5-0.40.3-0.4-0.40.40.4-0.3-0.5-0.3-0.30.20.30.5
Condit. Reinf. active responses0.20.31.20.60.60.5-0.5-0.5-0.20.4-0.4-0.50.40.4-0.5-1.1-0.4-0.40.50.30.9
Condit. Reinf. inactive responses0.20.21.00.40.40.4-0.4-0.20.00.3-0.1-0.10.10.1-0.5-1.0-0.4-0.50.6-0.10.6
Incentive salience index mean0.50.61.30.81.00.9-0.9-1.0-1.10.8-0.8-0.80.80.8-0.8-0.6-0.8-0.80.60.40.5
Condit. Reinf. lever presses1.11.53.61.21.51.2-1.2-1.6-1.91.2-1.5-1.41.41.5-0.9-0.2-1.0-0.90.60.91.2
Condit. Reinf. active minus inactive responses2.22.74.0-1.8-2.0-2.02.01.81.7-1.91.31.3-1.3-1.31.91.51.91.9-1.8-0.3-0.8
Condit. Reinf. active-inactive response ratio1.71.82.5-1.4-1.6-1.61.61.51.4-1.41.21.2-1.1-1.21.51.41.41.4-1.3-0.4-0.8
Condit. Reinf. active responses0.60.92.3-0.6-0.7-1.11.10.50.2-1.2-0.2-0.20.20.21.41.21.41.4-1.51.0-0.0
Condit. Reinf. inactive responses1.31.63.71.31.30.9-0.9-1.4-1.70.6-1.8-1.91.91.9-0.4-0.3-0.3-0.3-0.01.81.0
Condit. Reinf. lever presses0.40.51.40.80.60.8-0.8-0.8-1.20.6-0.9-0.90.90.9-0.7-0.2-0.7-0.70.40.5-0.3
Condit. Reinf. lever reinforcers received0.30.41.1-0.3-0.4-0.70.70.2-0.1-0.8-0.3-0.30.30.30.90.90.91.0-1.10.90.1
Conditioned reinforcement - actives0.80.84.0-0.6-0.40.1-0.10.50.30.21.01.1-1.1-1.1-0.6-0.0-0.6-0.80.6-1.6-2.0
Conditioned reinforcement - inactives2.22.58.3-0.9-0.80.0-0.11.21.70.12.12.0-2.1-2.2-1.0-1.8-0.8-1.10.9-2.9-2.5
Conditioned locomotion0.50.62.00.90.90.9-0.9-0.7-0.30.8-0.4-0.50.50.4-1.0-1.4-0.9-1.01.00.2-0.2
Patch foraging indifference point 0 sec0.81.32.81.21.31.0-1.0-1.3-1.71.1-1.5-1.41.41.5-0.7-0.2-0.7-0.60.41.30.8
Patch foraging indifference point AUC4.35.08.12.52.32.8-2.8-1.9-2.12.6-1.9-1.91.91.9-2.8-1.9-2.8-2.72.50.40.4
Delay disc. indifference point, 0s delay0.91.02.1-1.3-1.2-0.90.91.20.8-0.31.41.4-1.4-1.40.60.40.60.5-0.4-1.2-0.4
Delay disc. indifference point, 16s delay0.80.81.90.70.51.1-1.1-0.5-0.81.4-0.2-0.10.10.1-1.3-0.8-1.3-1.31.4-0.8-0.7
Delay disc. indifference point, 2s delay0.10.10.2-0.0-0.40.0-0.00.4-0.10.30.30.3-0.3-0.3-0.0-0.3-0.1-0.00.3-0.30.4
Delay disc. indifference point, 24s delay2.22.14.31.51.21.8-1.9-1.2-0.91.7-0.7-0.80.70.7-2.0-2.1-2.0-2.02.1-0.40.3
Delay disc. indifference point, 4s delay0.60.61.40.30.40.9-0.9-0.5-0.61.10.20.3-0.3-0.2-1.1-0.7-1.2-1.21.1-0.9-0.3
Delay disc. indifference point, 8s delay3.43.59.12.21.72.2-2.2-1.6-1.52.4-1.2-1.21.21.2-2.1-3.0-2.1-2.02.40.21.3
Indifference point function ln k4.15.88.9-2.6-2.6-3.03.02.32.4-2.92.22.1-2.1-2.12.81.82.92.8-2.6-0.6-0.8
Indifference point function log k4.15.88.9-2.6-2.6-3.03.02.32.4-2.92.22.1-2.1-2.12.81.82.92.8-2.6-0.6-0.8
Patch foraging total patch changes 0 sec0.71.22.61.11.20.9-0.9-1.2-1.60.9-1.5-1.51.51.5-0.5-0.0-0.5-0.40.21.50.7
Patch foraging total patch changes 12 sec4.45.78.52.72.92.8-2.8-2.5-2.72.7-2.4-2.32.32.3-2.5-1.7-2.5-2.42.31.11.2
Patch foraging total patch changes 18 sec1.11.42.21.41.21.5-1.5-1.1-1.31.5-1.1-1.01.11.1-1.4-0.6-1.4-1.31.20.50.2
Patch foraging total patch changes 24 sec0.91.11.71.21.01.1-1.1-1.1-1.31.1-1.3-1.31.31.3-0.9-0.5-0.9-0.80.70.90.5
Patch foraging total patch changes 6 sec4.46.59.22.82.83.0-3.0-2.5-2.93.0-2.5-2.52.52.5-2.8-1.8-2.8-2.72.51.00.8
Patch foraging time to switch 0 sec0.40.61.30.61.10.9-0.9-1.1-0.61.1-0.2-0.10.20.2-1.0-0.8-1.0-1.01.1-0.50.5
Patch foraging water rate 0 sec0.50.91.5-0.9-1.0-1.11.11.01.0-1.20.70.6-0.6-0.71.10.81.11.1-1.10.1-0.8
Patch foraging water rate 12 sec0.20.30.9-0.5-0.4-0.70.70.30.5-0.50.30.2-0.2-0.20.70.30.80.7-0.90.3-0.5
Patch foraging water rate 18 sec0.81.02.9-1.0-1.5-0.90.91.21.4-0.71.11.0-1.0-1.10.70.00.80.6-0.5-0.7-1.7
Patch foraging water rate 24 sec0.50.71.3-1.1-1.1-1.11.00.70.9-0.70.90.8-0.8-0.80.90.51.00.9-0.9-0.3-0.2
Patch foraging water rate 6 sec0.10.10.2-0.3-0.4-0.50.50.20.4-0.30.30.3-0.3-0.30.40.10.50.4-0.50.0-0.0
Seeking ratio, delayed vs. immediate footshock0.30.30.80.5-0.10.4-0.4-0.3-0.70.6-0.9-0.90.90.9-0.20.5-0.2-0.10.10.9-0.0
Distance traveled before self-admin0.60.71.4-0.8-1.1-0.40.41.20.7-0.51.11.1-1.1-1.10.00.10.0-0.10.1-1.2-1.1
Distance traveled after self-admin2.73.16.3-1.8-2.3-1.41.42.32.0-1.82.12.1-2.1-2.10.81.30.80.7-0.8-1.7-2.5
Extensor digitorum longus weight0.10.50.9-0.5-0.8-0.80.80.91.0-0.80.50.4-0.4-0.50.80.20.90.9-0.60.10.5
Bone: elastic displacement0.30.33.7-0.00.1-0.40.5-0.10.3-0.50.20.2-0.2-0.20.6-0.20.60.7-0.30.11.9
Bone: elastic work0.40.51.0-0.8-0.5-0.70.70.60.9-0.71.01.0-1.0-1.00.6-0.20.60.6-0.2-0.80.7
Bone: endosteal estimation4.49.714.3-3.6-3.8-3.63.53.73.5-3.33.13.0-3.1-3.13.12.43.13.0-2.9-1.6-1.4
Bone: endosteal perimeter4.59.414.4-3.6-3.8-3.53.53.73.2-3.32.92.9-2.9-2.93.13.03.02.9-2.9-1.5-1.8
Epididymis fat weight1.12.66.5-1.3-1.3-2.12.11.30.9-2.00.60.5-0.5-0.52.51.32.52.6-2.10.91.4
Delta time in closed arm before/after self-admin0.80.81.90.91.10.5-0.5-0.9-0.40.4-1.1-1.31.31.2-0.1-0.9-0.0-0.0-0.01.41.2
Delta time in open arm before/after self-admin2.92.86.1-2.2-1.8-1.21.21.61.1-0.82.02.2-2.1-2.00.72.30.60.5-0.8-2.0-2.5
Diff in mean of infusions in LGA sessions1.21.32.2-1.4-1.5-1.11.11.41.3-0.81.41.2-1.3-1.30.80.40.90.8-0.8-1.0-1.2
Delay discount exponential model param1.01.12.5-0.9-0.8-1.21.20.70.8-1.50.20.2-0.2-0.21.41.61.41.4-1.60.6-0.2
Extinction: sum of active levers before priming0.10.10.5-0.2-0.3-0.30.30.2-0.0-0.1-0.1-0.10.10.10.30.70.30.3-0.30.1-0.3
Active lever presses in extinction session 63.93.87.8-1.9-2.4-1.31.22.32.5-1.02.82.7-2.8-2.80.4-0.30.50.3-0.0-2.8-2.0
Bone: final force0.00.10.2-0.4-0.3-0.10.10.30.1-0.00.30.3-0.3-0.30.00.10.0-0.0-0.1-0.4-0.2
Bone: final moment0.00.10.1-0.4-0.2-0.30.30.30.1-0.20.10.1-0.1-0.10.30.10.30.3-0.3-0.00.3
Food consumed during 24 hour testing period0.70.83.71.00.90.9-0.9-0.9-0.40.9-0.5-0.70.70.6-0.9-1.9-0.8-0.90.90.31.0
Glucose0.00.10.2-0.3-0.1-0.30.3-0.40.3-0.30.1-0.0-0.0-0.00.30.10.40.3-0.50.2-0.2
Heart weight1.01.33.21.41.50.6-0.6-1.4-1.20.6-1.7-1.71.71.7-0.0-0.4-0.00.10.11.80.9
Delay discount hyperbolic model param0.70.71.9-0.8-0.6-1.01.00.50.7-1.20.20.1-0.1-0.11.11.41.21.1-1.30.5-0.2
Intermittent access intake day 1-15 change3.33.25.0-2.2-2.0-1.81.82.11.4-1.91.92.0-2.0-1.91.41.91.41.2-1.4-1.6-2.0
Intermittent access intake escalation3.53.45.2-2.3-2.1-1.91.92.21.3-2.01.81.9-1.9-1.81.62.21.51.5-1.6-1.4-1.9
Intermittent access intake escalation 24.44.46.5-2.5-2.5-2.02.02.51.6-1.92.42.4-2.4-2.41.52.11.41.3-1.4-2.0-2.5
Intermitt. access day 1 inactive lever presses0.20.31.1-0.5-0.5-0.50.50.60.3-0.30.60.6-0.6-0.50.5-0.20.50.5-0.3-0.41.1
Intermitt. access day 15 inactive lever presses0.10.10.60.10.30.0-0.0-0.10.4-0.10.10.1-0.1-0.1-0.0-0.80.0-0.00.10.10.3
Intermitt. access escalation Index1.31.22.3-1.1-1.0-1.31.31.01.2-1.50.70.6-0.6-0.61.41.01.41.4-1.40.10.2
Intermittent access day 1 total infusions0.20.20.7-0.4-0.1-0.30.30.30.8-0.40.60.5-0.5-0.60.2-0.60.30.2-0.2-0.5-0.1
Intermittent access day 15 total infusions2.22.53.8-2.0-1.5-1.81.81.71.5-1.91.51.4-1.5-1.51.51.51.61.5-1.7-0.9-1.4
Intermittent access terminal intake (last 3 days)1.71.83.0-1.7-1.2-1.41.31.41.4-1.41.61.6-1.6-1.61.01.01.10.9-1.1-1.3-1.7
Intermittent access total infusions0.80.91.5-1.2-0.7-1.11.10.91.2-1.21.11.0-1.0-1.10.90.41.00.8-0.9-0.7-0.8
Intermittent access day 1 locomotion0.10.20.6-0.4-0.0-0.50.50.20.4-0.50.10.1-0.1-0.10.60.20.60.6-0.70.20.1
Intermittent access day 15 total locomotion0.50.51.00.60.90.8-0.9-0.8-0.70.9-0.3-0.30.30.3-1.0-0.7-0.9-1.00.8-0.3-0.4
Intermittent access total locomotion0.20.30.60.20.50.5-0.5-0.4-0.10.50.10.2-0.2-0.2-0.7-0.8-0.7-0.70.6-0.6-0.5
Intermittent access standard deviation2.22.43.8-1.8-1.7-1.61.62.01.5-1.61.71.6-1.7-1.71.21.01.31.1-1.3-1.3-1.7
Left kidney weight0.31.02.31.30.80.8-0.7-0.8-0.90.8-1.4-1.51.51.4-0.4-0.7-0.3-0.30.21.50.8
Right kidney weight1.43.98.02.52.01.8-1.7-1.9-2.01.7-2.7-2.82.82.7-1.1-1.0-1.1-1.00.72.61.4
Cocaine induced anxiety0.50.63.1-0.8-0.9-0.50.50.91.00.00.90.9-0.9-0.90.20.00.20.2-0.0-0.9-1.7
Post-drug Anxiety0.20.30.70.60.70.4-0.4-0.6-0.60.8-0.6-0.50.50.6-0.2-0.2-0.3-0.20.40.50.1
Baseline Anxiety1.11.24.71.21.60.7-0.7-1.6-1.20.3-1.3-1.21.21.3-0.3-0.3-0.3-0.20.11.32.2
Tail length0.20.73.20.50.4-0.20.2-0.7-0.2-0.5-1.1-1.21.21.10.60.50.70.7-0.91.80.1
Length with tail0.30.92.41.00.90.7-0.7-1.1-1.00.4-1.4-1.51.51.4-0.30.3-0.3-0.3-0.11.5-0.5
Length without tail0.20.52.10.60.40.9-0.9-0.3-0.60.7-0.5-0.50.50.5-0.90.0-0.9-1.00.70.2-1.4
Times rat made contact with spout0.20.31.0-0.3-0.30.0-0.00.30.30.00.70.7-0.7-0.7-0.3-1.0-0.2-0.30.5-0.9-0.1
Lifetime Intake0.20.30.5-0.6-0.2-0.50.50.50.7-0.60.70.6-0.6-0.70.4-0.20.40.3-0.3-0.5-0.5
Liver weight, left0.20.41.9-0.5-0.3-0.70.70.40.4-0.70.10.0-0.0-0.10.80.30.90.8-0.80.41.4
Liver weight, right0.30.51.3-0.6-0.1-0.70.70.10.1-0.8-0.1-0.10.10.10.91.10.90.9-1.00.51.0
Locomotor activity0.00.00.40.20.00.1-0.10.20.1-0.00.1-0.00.0-0.0-0.2-0.4-0.1-0.10.10.0-0.7
Locomotor testing distance0.00.10.8-0.1-0.00.0-0.00.20.3-0.10.20.2-0.2-0.2-0.2-0.1-0.1-0.20.1-0.2-0.9
Locomotor testing rearing0.50.82.0-1.2-0.9-0.80.81.00.9-0.81.01.0-1.0-1.00.61.40.50.5-0.6-0.8-1.1
Locomotion in novel chamber2.93.65.1-2.2-2.0-2.01.91.92.2-1.92.22.3-2.3-2.21.51.51.51.4-1.6-1.6-1.7
Locomotion in novel chamber post-restriction0.40.54.2-0.1-0.30.4-0.40.1-0.10.20.30.4-0.3-0.3-0.70.9-0.8-0.90.4-0.8-2.0
Fecal boli incidents, locomotor time 10.80.92.5-0.4-1.1-0.10.01.11.30.21.21.0-1.0-1.2-0.4-1.6-0.3-0.40.9-1.0-1.4
Change in fecal boli incidents, locomotor task0.50.51.20.31.00.4-0.4-1.0-1.10.3-0.8-0.60.70.8-0.21.1-0.3-0.2-0.20.40.8
Time >=10cm from walls, locomotor time 10.30.32.9-0.1-0.00.5-0.50.10.10.6-0.0-0.20.10.0-0.7-0.2-0.6-0.80.6-0.5-1.7
Bouts of movement, locomotor time 10.91.05.80.90.41.1-1.1-0.3-0.11.2-0.1-0.20.20.1-1.3-2.4-1.2-1.21.6-0.40.6
Total resting periods, locomotor time 11.61.77.71.20.61.5-1.5-0.5-0.21.5-0.1-0.20.20.1-1.8-2.8-1.7-1.82.0-0.70.0
Rest time, locomotor task time 10.80.92.5-0.4-0.60.4-0.40.50.70.21.11.2-1.2-1.2-0.9-1.2-0.9-1.01.2-1.6-0.8
Distance moved, locomotor task time 11.11.24.20.10.9-0.30.3-0.9-1.0-0.4-1.4-1.31.31.40.92.00.80.9-1.41.80.8
Vertical activity count, locomotor time 10.40.51.70.10.3-0.10.1-0.3-0.6-0.2-0.9-1.01.01.00.41.30.40.5-0.81.10.0
Time >=10cm from walls, locomotor time 20.20.20.6-0.10.00.4-0.40.50.40.10.20.1-0.2-0.2-0.6-0.6-0.5-0.60.7-0.5-0.0
Bouts of movement, locomotor time 22.52.65.51.51.52.0-2.0-1.3-1.52.2-0.6-0.50.50.6-2.2-1.8-2.3-2.22.3-0.80.1
Total resting periods, locomotor time 22.72.96.01.51.52.1-2.2-1.3-1.52.3-0.6-0.40.40.5-2.4-1.9-2.5-2.42.5-1.0-0.2
Rest time, locomotor task time 21.01.23.00.80.41.3-1.3-0.6-0.71.20.10.1-0.1-0.1-1.7-1.2-1.7-1.71.6-1.1-0.7
Distance moved, locomotor task time 20.80.92.2-0.7-0.2-1.01.10.40.7-1.3-0.2-0.30.30.21.30.81.41.4-1.41.11.5
Vertical activity count, locomotor time 20.20.20.4-0.6-0.4-0.50.50.60.7-0.60.20.0-0.1-0.20.5-0.10.60.5-0.30.10.4
Light reinforcement 10.10.20.60.50.70.3-0.3-0.8-0.30.4-0.5-0.50.50.5-0.2-0.0-0.2-0.10.20.60.5
Light reinforcement 21.41.96.71.71.31.6-1.6-1.1-0.51.4-0.6-0.70.70.6-1.6-2.6-1.5-1.51.80.21.2
Bone: marrow area4.59.814.4-3.7-3.8-3.63.63.73.5-3.33.23.1-3.1-3.13.12.43.23.0-2.8-1.6-1.4
Bone: maximum diameter4.38.011.2-3.1-3.3-3.23.23.33.2-3.32.52.4-2.4-2.43.02.83.02.9-2.9-0.9-1.8
Bone: maximum force0.40.71.3-1.2-1.0-0.80.71.01.0-0.61.11.1-1.1-1.10.5-0.00.50.4-0.3-1.1-0.5
Bone: maximum moment0.40.61.1-1.1-0.9-0.90.90.90.9-0.71.00.9-0.9-0.90.7-0.10.80.7-0.5-0.70.1
Mean time between licks in bursts0.40.51.70.50.50.1-0.1-0.8-1.0-0.2-1.0-1.01.01.10.30.70.30.4-0.51.30.2
Mean num. licks in bursts2.02.34.4-1.7-2.1-1.81.81.81.2-1.91.21.1-1.1-1.21.71.41.81.7-1.8-0.2-0.8
Cd content in liver2.52.85.32.11.91.2-1.2-1.6-1.51.1-2.2-2.32.32.2-0.6-1.1-0.6-0.40.42.32.3
Co content in liver1.31.65.51.51.40.3-0.3-1.0-0.8-0.1-1.8-1.91.91.80.4-0.10.40.5-0.62.41.6
Cu content in liver4.75.79.62.42.62.9-2.9-2.5-2.32.9-1.5-1.31.31.4-3.0-2.6-3.1-3.03.1-0.21.5
Fe content in liver1.11.42.01.31.41.3-1.3-1.4-1.31.3-1.0-0.90.91.0-1.2-0.9-1.3-1.21.20.41.2
K content in liver0.50.52.2-0.5-0.20.3-0.30.2-0.10.70.70.8-0.8-0.7-0.70.1-0.8-0.80.8-1.5-0.7
Mg content in liver0.50.51.30.10.30.8-0.8-0.2-0.51.00.20.4-0.3-0.3-1.0-0.3-1.1-1.11.1-1.0-0.2
Mn content in liver3.23.79.21.41.32.3-2.3-1.3-1.02.5-0.10.0-0.0-0.0-2.8-2.9-2.7-2.83.0-1.50.2
Na content in liver1.01.02.60.60.71.2-1.2-0.7-0.71.4-0.00.1-0.1-0.0-1.5-0.9-1.6-1.61.6-1.00.0
Rb content in liver0.10.10.90.10.20.1-0.20.20.50.20.30.2-0.2-0.3-0.3-1.0-0.2-0.30.4-0.40.1
Se content in liver13.516.527.14.34.35.0-5.0-4.2-4.15.2-2.9-2.72.82.8-5.0-4.1-5.1-4.94.90.21.3
Sr content in liver0.10.10.30.20.20.3-0.3-0.2-0.20.4-0.2-0.20.20.2-0.3-0.5-0.2-0.30.30.00.6
Zn content in liver1.11.21.61.31.31.2-1.2-1.1-1.21.2-1.0-0.90.90.9-1.1-1.0-1.1-1.01.10.41.3
Bone: minimum diameter5.911.016.6-3.6-3.6-4.04.03.63.3-4.12.42.3-2.3-2.33.93.73.93.8-4.0-0.4-1.9
Time in familiar zone, hab. session 10.20.20.3-0.3-0.6-0.50.50.30.6-0.30.40.4-0.4-0.40.5-0.10.50.5-0.3-0.1-0.1
Time in novel zone, hab. session 10.30.30.60.50.60.7-0.7-0.2-0.70.6-0.4-0.30.30.4-0.7-0.2-0.7-0.70.6-0.00.2
Total zone transitions, hab. session 10.20.20.7-0.10.20.3-0.3-0.0-0.00.30.40.5-0.5-0.5-0.6-0.8-0.6-0.60.7-0.90.0
Total locomotion distance, hab. session 11.41.95.21.31.41.6-1.7-1.4-1.01.6-0.6-0.60.60.6-1.8-2.3-1.7-1.81.8-0.30.9
Locomotion velocity, hab. session 12.53.57.71.92.02.2-2.2-2.0-1.62.2-1.1-1.21.11.1-2.3-2.8-2.2-2.32.20.01.1
Time in familiar zone, hab. session 20.90.93.71.00.80.1-0.1-0.7-0.6-0.2-1.3-1.31.31.30.5-0.00.50.7-0.51.91.4
Time in novel zone, hab. session 20.20.20.7-0.10.10.4-0.40.10.20.40.40.4-0.4-0.4-0.7-0.4-0.6-0.70.7-0.8-0.5
Total zone transitions, hab. session 20.60.71.80.91.10.9-0.9-1.1-1.20.7-0.9-0.80.80.8-0.7-0.5-0.7-0.70.50.51.4
Total locomotion distance, hab. session 21.31.83.21.61.61.3-1.3-1.7-1.31.1-1.3-1.41.31.3-1.0-1.6-0.9-0.90.91.11.8
Locomotion velocity, hab. session 21.11.52.61.41.51.3-1.3-1.6-1.31.2-1.1-1.11.11.1-1.1-1.5-1.1-1.11.10.71.4
Novel to familiar place preference ratio4.14.311.6-2.3-2.2-1.11.02.22.3-0.83.13.1-3.1-3.10.1-0.30.1-0.10.4-3.4-1.9
Novelty place preference4.44.411.7-2.4-2.2-1.21.12.22.3-0.83.13.2-3.2-3.20.1-0.10.2-0.10.3-3.4-1.9
Time in novel zone, NPP test4.14.210.7-2.3-2.2-1.21.12.22.4-0.93.03.1-3.1-3.10.2-0.10.2-0.00.3-3.3-1.8
Total zone transitions, NPP test0.71.01.81.11.31.1-1.1-1.3-1.10.9-1.0-1.11.01.0-0.9-0.9-0.9-0.90.60.61.0
Total locomotion distance, NPP test2.53.56.22.12.12.2-2.2-2.1-1.62.0-1.4-1.51.51.4-2.1-2.5-2.0-2.11.90.51.0
Locomotion velocity, NPP test2.13.04.51.92.02.1-2.1-1.9-1.61.9-1.4-1.41.41.4-2.0-2.1-1.9-2.01.80.50.7
Intraocular pressure0.20.31.00.60.90.4-0.4-0.9-0.80.4-0.7-0.60.60.6-0.2-0.3-0.2-0.10.20.61.0
Delta distance traveled before/after self-admin2.22.43.7-1.7-1.7-1.71.71.71.5-1.81.41.5-1.4-1.41.61.91.51.5-1.6-0.7-1.3
Delta ambulatory time before/after self-admin3.23.55.2-2.1-1.9-2.12.12.01.9-2.31.71.7-1.7-1.71.92.21.91.9-1.9-0.8-1.4
Parametrial fat weight0.61.24.61.20.90.5-0.5-1.0-1.00.2-1.7-1.81.81.7-0.0-0.30.10.1-0.32.10.5
Pavlov. Cond. lever latency0.20.21.00.40.4-0.10.1-0.3-0.2-0.2-0.6-0.60.60.60.50.60.40.5-0.51.00.4
Pavlov. Cond. magazine entry latency0.70.91.41.00.91.1-1.1-1.0-0.91.2-0.9-1.00.90.9-1.1-1.2-1.0-1.10.90.30.4
Pavlov. Cond. change in total contacts0.10.10.90.20.10.3-0.3-0.20.10.2-0.1-0.30.20.2-0.3-1.0-0.2-0.30.20.20.6
Pavlov. Cond. index score0.50.61.60.60.51.0-1.0-0.6-0.51.1-0.3-0.40.40.3-1.1-1.3-1.0-1.21.0-0.30.2
Pavlov. Cond. latency score0.30.41.00.50.40.8-0.8-0.6-0.50.9-0.3-0.30.30.3-1.0-0.9-0.9-1.00.8-0.30.0
Pavlov. Cond. lever contacts0.40.40.90.40.50.8-0.8-0.6-0.70.9-0.3-0.40.30.3-0.9-0.9-0.9-1.00.7-0.20.3
Pavlov. Cond. magazine entry number0.10.20.7-0.3-0.2-0.20.20.40.1-0.40.40.5-0.5-0.40.20.90.10.2-0.1-0.4-0.8
Pavlov. Cond. intertrial magazine entries0.20.21.50.40.50.4-0.4-0.4-0.20.3-0.1-0.20.20.1-0.4-1.2-0.4-0.40.5-0.10.3
Pavlov. Cond. lever-magazine prob. diff.0.50.61.70.60.50.9-0.9-0.7-0.51.0-0.3-0.40.40.3-1.1-1.3-1.0-1.11.0-0.30.2
Pavlov. Cond. response bias0.20.31.00.40.30.5-0.6-0.4-0.40.7-0.3-0.40.30.3-0.6-1.0-0.5-0.70.5-0.00.5
Pavlov. Cond. lever latency1.72.33.1-1.8-1.6-1.71.71.61.7-1.51.51.6-1.6-1.51.51.51.41.4-1.2-0.9-0.9
Pavlov. Cond. magazine entry latency0.40.43.60.80.30.6-0.6-0.40.00.5-0.3-0.50.40.3-0.7-1.9-0.5-0.60.60.20.5
Pavlov. Cond. change in total contacts0.40.50.90.90.80.7-0.7-0.8-0.90.6-0.9-0.90.90.9-0.6-0.5-0.6-0.60.40.70.6
Pavlov. Cond. index score1.11.44.01.41.11.4-1.4-1.1-1.01.2-0.9-1.11.00.9-1.4-2.0-1.3-1.41.20.40.5
Pavlov. Cond. latency score1.01.34.31.31.01.3-1.3-1.0-0.71.1-0.8-0.90.90.8-1.4-2.1-1.2-1.31.20.30.5
Pavlov. Cond. lever contacts1.52.03.21.71.51.5-1.5-1.5-1.81.3-1.6-1.71.61.6-1.3-1.0-1.3-1.21.01.10.7
Pavlov. Cond. magazine entry number2.63.18.4-2.1-1.8-2.02.01.81.4-1.81.41.6-1.6-1.51.92.91.71.8-1.7-0.7-1.1
Pavlov. Cond. intertrial magazine entries1.11.42.2-1.5-1.5-1.41.41.31.2-1.21.11.2-1.1-1.11.31.21.21.3-1.0-0.6-0.3
Pavlov. Cond. lever-magazine prob. diff.1.01.33.81.30.91.3-1.3-1.0-0.81.2-0.7-0.90.90.8-1.4-1.9-1.3-1.41.20.20.2
Pavlov. Cond. response bias1.52.13.11.81.51.6-1.6-1.4-1.61.4-1.5-1.61.61.5-1.4-1.5-1.4-1.41.20.90.7
Time in closed arm before self-admin0.80.92.2-0.7-1.2-0.50.51.31.5-0.61.41.3-1.3-1.40.1-0.70.20.10.3-1.3-0.8
Time in closed arm after self-admin0.30.30.80.90.50.5-0.5-0.2-0.20.3-0.6-0.70.70.6-0.4-0.8-0.4-0.30.50.60.3
Time in open arm before self-admin0.30.31.40.30.3-0.20.3-0.3-0.4-0.2-0.5-0.50.50.50.60.00.50.6-0.50.91.2
Time in open arm after self-admin0.91.03.6-1.5-0.9-0.80.80.70.2-0.51.11.3-1.2-1.10.51.90.40.4-0.7-1.2-1.1
Bone: periosteal estimation2.44.97.2-2.5-2.7-2.62.62.72.4-2.52.01.9-2.0-2.02.31.82.42.3-2.2-0.8-1.1
Bone: periosteal perimeter2.94.86.7-2.5-2.6-2.62.62.52.3-2.51.91.8-1.8-1.82.42.22.42.4-2.3-0.6-1.1
Bone: post-yield work0.50.71.2-1.1-1.0-1.00.90.80.9-0.80.90.9-0.9-0.90.80.40.80.7-0.7-0.6-0.7
Progressive ratio test 1 active lever presses0.40.40.7-0.7-0.4-0.50.50.60.8-0.40.90.8-0.8-0.90.3-0.20.40.3-0.3-0.7-0.7
Progressive ratio test 1 breakpoint0.40.40.9-0.8-0.5-0.60.60.60.8-0.50.90.9-1.0-0.90.4-0.10.40.3-0.4-0.8-0.6
Progressive ratio test 1 inactive lever presses1.61.83.3-1.6-1.0-1.51.51.21.8-1.51.61.6-1.6-1.61.20.11.31.2-1.3-0.9-0.0
Progressive ratio test 2 active lever presses1.01.12.4-1.1-0.7-0.70.70.91.4-0.51.61.5-1.5-1.60.2-0.60.30.10.0-1.5-1.4
Progressive ratio test 2 breakpoint1.11.22.9-1.1-0.7-0.70.60.91.5-0.51.71.6-1.6-1.70.1-0.90.30.10.1-1.7-1.4
Progressive ratio test 2 inactive lever presses1.01.23.7-1.1-0.4-0.60.50.81.3-0.51.71.7-1.7-1.70.0-0.80.1-0.10.1-1.9-1.0
Incentive Sensitization - Responses1.81.83.8-1.5-1.0-1.01.01.31.9-0.91.91.8-1.8-1.90.4-0.40.60.4-0.2-1.8-1.6
Incentive Sensitization - Breakpoint1.31.43.1-1.2-0.8-0.80.81.11.8-0.71.71.6-1.6-1.70.3-0.70.40.2-0.0-1.6-1.4
Sum of active levers in priming session hrs 5-60.10.10.60.1-0.3-0.10.00.20.4-0.10.10.0-0.1-0.10.0-0.70.10.10.2-0.10.3
Progressive ratio0.70.83.90.40.2-0.40.4-0.0-0.3-0.5-0.9-1.00.90.90.9-0.21.01.1-0.71.82.0
Food seeking constrained by brief footshock0.20.30.60.30.70.7-0.7-0.4-0.60.8-0.4-0.50.50.4-0.7-0.4-0.7-0.70.4-0.0-0.1
Seeking ratio, punishment vs. effort0.70.82.30.10.40.9-0.9-0.4-0.31.10.30.3-0.3-0.3-1.4-0.3-1.4-1.51.0-1.3-1.5
Retroperitoneal fat weight0.31.16.1-0.10.3-0.90.9-0.6-0.2-0.8-0.6-0.70.60.71.40.21.41.5-1.21.42.5
Reaction time number correct2.63.85.5-2.3-2.2-2.12.12.12.3-1.72.12.1-2.1-2.11.81.61.81.7-1.5-1.4-1.5
Reaction time mean minus median0.30.31.30.20.2-0.40.4-0.20.4-0.7-0.5-0.70.70.50.6-0.10.70.7-0.81.10.3
Reaction time mean minus median AUC0.30.41.40.30.2-0.40.4-0.30.3-0.7-0.5-0.70.70.60.6-0.10.80.7-0.81.20.5
Reaction time num false alarms0.20.31.00.30.20.1-0.1-0.0-0.70.1-0.8-0.80.80.80.21.00.10.2-0.21.0-0.6
Reaction time num false alarms AUC0.30.41.30.20.2-0.00.0-0.1-0.7-0.0-0.8-0.80.80.80.31.10.30.4-0.41.0-0.6
Reaction time trials correct on left2.63.85.5-2.3-2.2-2.12.12.12.3-1.72.12.1-2.1-2.11.81.61.81.7-1.5-1.4-1.5
Reaction time trials on left2.53.65.2-2.3-2.2-2.12.12.02.3-1.72.02.0-2.0-2.01.81.61.81.7-1.5-1.2-1.4
Reaction time mean1.31.93.61.81.61.1-1.0-1.4-1.20.6-1.8-1.91.91.8-0.6-1.2-0.5-0.40.41.71.7
Reaction time mean AUC1.41.93.51.81.61.2-1.2-1.6-1.40.8-1.8-1.91.81.8-0.8-1.2-0.7-0.60.61.51.5
Median of all reaction times1.52.04.01.91.61.2-1.2-1.4-1.40.8-1.8-1.81.81.8-0.7-1.4-0.7-0.60.71.62.0
Reaction time omissions0.81.02.60.1-0.4-1.01.00.50.9-1.3-0.4-0.70.70.51.5-0.01.61.6-1.51.60.7
Reaction time false alarm rate1.01.43.01.31.21.0-1.0-1.0-1.70.8-1.7-1.71.71.7-0.60.2-0.6-0.50.31.50.1
Reaction time premature initiation rate0.60.81.50.81.10.7-0.7-1.0-1.00.7-1.1-1.21.21.2-0.5-0.4-0.4-0.50.01.20.9
Reaction time premature initiations0.10.10.5-0.3-0.1-0.30.30.10.3-0.2-0.1-0.20.20.10.40.30.50.4-0.70.60.0
Std. dev. reaction times0.81.24.31.01.00.1-0.1-1.0-0.4-0.3-1.5-1.71.61.50.5-0.40.60.6-0.82.11.3
Reaction time trials completed2.53.65.2-2.3-2.2-2.12.12.02.3-1.72.02.0-2.0-2.01.81.61.81.7-1.5-1.2-1.4
Reaction time trials AUC2.33.35.1-2.2-2.1-2.02.01.92.2-1.72.01.9-1.9-1.91.71.51.71.7-1.4-1.2-1.3
Run reversals in cocaine runway, females0.20.21.30.30.30.4-0.5-0.4-0.30.50.10.1-0.1-0.1-0.5-1.1-0.5-0.50.6-0.50.7
Run reversals in cocaine runway, males3.23.14.72.01.62.2-2.2-2.0-2.01.9-1.6-1.61.61.6-2.1-1.3-2.1-2.11.80.50.0
Latency to leave start box in cocaine runway2.72.96.3-1.5-1.3-2.12.21.31.5-2.30.70.6-0.6-0.62.51.92.42.5-2.30.70.7
Latency to leave start box in cocaine runway, F3.53.86.6-2.0-1.8-2.42.41.71.8-2.51.31.3-1.3-1.22.62.32.52.5-2.4-0.00.1
Latency to leave start box in cocaine runway, M0.60.61.60.00.1-0.70.70.20.2-0.9-0.5-0.60.50.51.10.31.11.1-1.11.31.0
Std. dev. time between licks in bursts1.82.26.21.71.61.1-1.1-1.6-1.91.1-1.8-1.81.81.8-0.6-1.0-0.6-0.40.61.62.5
Total sessions with >9 infusions0.20.20.70.30.80.5-0.5-0.6-0.80.5-0.2-0.10.10.2-0.5-0.2-0.6-0.50.5-0.1-0.2
Short access day 1 total inactive lever presses2.02.23.3-1.5-1.5-1.61.61.81.7-1.51.81.8-1.8-1.81.30.61.31.3-1.2-1.2-0.8
Short access day 10 total inactive lever presses0.20.21.30.60.30.3-0.30.00.10.3-0.2-0.30.30.2-0.3-1.1-0.2-0.20.30.40.7
Short access day 1 total infusions0.60.72.50.91.00.9-0.9-0.7-0.60.7-0.5-0.50.40.4-0.9-1.6-0.8-0.80.9-0.00.8
Short access day 10 total infusions0.80.92.71.01.30.6-0.6-1.1-0.70.5-1.1-1.21.21.1-0.3-1.1-0.2-0.20.21.31.6
Short access total infusions0.10.10.70.40.50.4-0.4-0.2-0.20.3-0.1-0.10.10.1-0.4-0.8-0.4-0.40.5-0.10.1
Short access day 1 locomotion0.20.20.5-0.60.2-0.30.3-0.0-0.1-0.20.50.7-0.7-0.60.20.30.20.2-0.3-0.70.3
Short access day 10 total locomotion0.20.21.60.00.10.1-0.20.00.60.20.40.3-0.3-0.4-0.3-1.3-0.2-0.30.5-0.40.2
Short access total locomotion0.20.20.60.20.80.4-0.4-0.6-0.50.3-0.2-0.10.10.2-0.4-0.2-0.4-0.40.3-0.10.7
One hour access (0.3 mA shock)3.23.77.1-2.3-1.8-1.61.61.92.5-1.62.72.6-2.6-2.70.90.11.10.8-0.6-2.4-2.1
Compulsive drug intake1.51.53.4-1.2-1.1-1.51.51.11.4-1.80.80.7-0.7-0.81.60.81.61.5-1.50.20.7
One hour access (shock baseline)1.01.12.7-1.4-0.9-0.90.90.91.0-0.81.31.4-1.4-1.30.60.80.60.5-0.4-1.3-1.6
Social response proportion3.43.75.3-2.1-2.1-2.02.02.22.1-1.62.32.3-2.3-2.31.51.41.51.5-1.3-1.7-1.9
Social responses0.91.22.3-1.3-0.9-1.21.21.20.8-0.91.01.0-1.0-1.01.11.51.01.0-1.1-0.5-1.3
Social time0.20.21.4-0.20.20.2-0.2-0.3-0.90.5-0.2-0.00.10.1-0.21.2-0.3-0.3-0.0-0.3-1.1
Soleus weight0.92.55.0-1.7-1.6-1.91.91.62.2-1.81.61.5-1.5-1.61.80.61.81.7-1.3-0.80.4
Bone: stiffness0.40.72.1-1.1-1.0-0.80.71.00.9-0.70.90.9-0.9-0.90.50.40.60.4-0.5-0.8-1.5
Tibialis anterior weight0.41.43.0-1.2-1.6-1.21.21.61.7-1.21.31.3-1.3-1.31.00.81.00.9-0.8-0.8-0.5
Time to tail flick, vehicle, before self-admin0.20.20.60.40.40.6-0.6-0.3-0.30.5-0.00.1-0.0-0.0-0.6-0.6-0.7-0.60.7-0.2-0.8
Time to tail flick, vehicle, after self-admin0.60.71.0-1.0-0.8-0.90.80.80.8-1.00.90.9-0.9-0.90.70.70.70.6-0.6-0.7-0.4
Time to tail flick, test, before self-admin2.82.85.7-2.1-1.7-1.51.51.71.6-1.32.12.1-2.1-2.10.91.21.00.8-0.9-1.8-2.4
Time to tail flick, test, after self-admin1.01.01.9-1.0-1.4-1.11.11.31.0-1.11.11.1-1.1-1.11.00.71.00.9-0.9-0.4-0.4
Delta time to tail flick, vehicle, before/after SA1.11.11.9-1.2-1.4-1.11.11.31.4-1.21.21.2-1.2-1.20.80.30.90.7-0.7-1.1-0.2
Delta time to tail flick, test, before/after SA0.20.10.90.50.10.2-0.2-0.1-0.10.1-0.4-0.40.40.4-0.0-0.5-0.00.00.10.61.0
Tibia length0.20.41.50.70.50.3-0.3-0.6-0.70.1-1.0-1.01.01.00.00.6-0.00.1-0.31.20.0
Ambulatory time before self-admin0.30.41.0-0.5-1.0-0.20.21.00.4-0.50.80.8-0.8-0.8-0.10.0-0.1-0.10.2-0.9-0.6
Ambulatory time after self-admin4.95.49.5-2.4-3.0-1.81.83.12.7-2.22.92.9-2.9-3.01.01.11.00.8-0.7-2.6-2.8
Bone: tissue strength0.20.21.2-0.3-0.2-0.40.40.10.3-0.30.20.2-0.2-0.20.4-0.30.50.5-0.3-0.01.1
Total heroin consumption0.50.62.30.80.50.9-0.9-0.5-0.21.1-0.3-0.50.40.4-1.0-1.5-0.9-1.00.9-0.00.1
Bone: trabecular number1.82.84.9-2.0-2.0-1.71.72.02.2-1.62.02.0-2.0-2.01.20.81.31.1-0.9-1.5-1.2
Bone: trabecular spacing1.92.54.81.91.91.2-1.2-1.9-1.90.8-2.2-2.22.22.2-0.6-0.7-0.6-0.50.32.11.5
Bone: trabecular thickness1.41.72.6-1.5-1.5-1.51.51.31.5-1.61.31.2-1.3-1.31.30.81.41.3-1.3-0.5-0.9
Bone: trabecular tissue density0.60.92.5-0.9-1.0-1.01.01.10.7-1.10.60.7-0.6-0.61.01.60.91.0-1.0-0.1-1.0
Water consumed over 24 hours0.40.51.8-0.5-0.6-0.20.20.60.70.01.11.0-1.0-1.1-0.2-1.3-0.1-0.30.5-1.20.3
Number of responses in last shaping day0.10.10.4-0.2-0.0-0.50.50.20.4-0.60.20.2-0.2-0.20.5-0.00.60.6-0.50.20.5