Hub : Genes

Hecw2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_039083601.1 0.07 0.05 3.6e-06 0.03 0.03 0.03 0.03 1.8e-04 2.1e-04 5.8e-04 5.3e-04
2 Adipose alternative TSS XM_006244912.4 0.08 0.06 2.1e-05 0.03 0.03 0.03 0.03 1.1e-04 2.1e-04 1.7e-04 2.0e-04
3 PL isoform ratio XM_039083600.1 0.02 0.02 7.5e-03 0 0.01 -0 0 9.2e-02 6.7e-02 7.2e-01 2.6e-01
4 Adipose intron excision ratio chr9_55488290_55492328 0.03 0.02 2.4e-03 0.01 0.02 0.01 0.01 1.3e-02 5.8e-03 3.2e-02 2.8e-02
5 Adipose isoform ratio XM_006244912.4 0.08 0.06 3.1e-05 0.01 0.03 0.03 0.03 1.1e-02 3.4e-04 6.2e-04 6.5e-04
6 NAcc alternative TSS XM_039083601.1 0.02 0.02 7.7e-03 0.02 0.01 0.02 0.02 3.2e-03 8.2e-03 2.1e-03 2.3e-03
7 NAcc gene expression Hecw2 0.07 0.04 6.0e-08 0.03 0.06 0.06 0.06 6.8e-05 4.0e-07 3.9e-07 1.4e-07
8 Brain intron excision ratio chr9_55408739_55424386 0.06 0.06 1.3e-03 0.04 0.03 0.03 0.03 2.4e-04 1.0e-03 3.4e-04 6.7e-04
9 Brain intron excision ratio chr9_55424495_55428967 0.07 0.06 1.4e-03 0.04 0.03 0.04 0.03 2.1e-04 1.0e-03 2.7e-04 6.4e-04
10 Adipose gene expression Hecw2 0.46 0.14 0.0e+00 0.18 0.2 0.2 0.2 6.6e-20 3.3e-22 6.2e-22 7.7e-22
11 Adipose alternative TSS XM_039083601.1 0.2 0.12 1.7e-10 0.06 0.06 0.06 0.06 3.5e-07 9.2e-08 9.0e-07 4.8e-07
12 RMTg gene expression Hecw2 0.37 0.16 7.8e-05 0.03 0.15 0.13 0.12 4.6e-02 8.7e-05 2.2e-04 4.5e-04
13 Brain mRNA stability Hecw2 0.21 0.09 5.6e-17 0.15 0.17 0.16 0.17 3.5e-14 5.9e-16 7.8e-15 1.9e-15
14 BLA mRNA stability Hecw2 0.18 0.09 2.7e-07 0.15 0.15 0.14 0.14 2.2e-08 2.1e-08 9.5e-08 8.6e-08
15 NAcc mRNA stability Hecw2 0.09 0.05 5.6e-09 0.07 0.06 0.06 0.06 2.8e-08 8.2e-08 5.9e-08 2.0e-07
16 PL gene expression Hecw2 0.06 0.03 1.7e-05 0.05 0.05 0.04 0.04 7.1e-06 8.5e-06 3.6e-05 3.0e-05
17 Brain alternative TSS XM_039083601.1 0.05 0.05 4.6e-03 0.02 0.01 0.01 0.01 2.6e-03 7.5e-02 2.0e-02 2.2e-02
18 Brain gene expression Hecw2 0.26 0.13 0.0e+00 0.21 0.2 0.14 0.2 4.1e-19 1.7e-18 2.1e-13 1.2e-18
19 PL mRNA stability Hecw2 0.19 0.09 1.7e-16 0.17 0.16 0.16 0.17 4.2e-18 9.0e-17 9.4e-18 4.3e-18
20 Adipose mRNA stability Hecw2 0.14 0.07 7.8e-13 0.08 0.08 0.07 0.07 1.8e-09 3.6e-09 1.2e-08 1.6e-08
21 Liver isoform ratio XM_039083601.1 0.03 0.02 6.7e-03 0.01 0 0.01 0.01 1.4e-02 1.2e-01 3.5e-02 3.8e-02
22 Liver gene expression Hecw2 0.2 0.09 0.0e+00 0.14 0.14 0.15 0.15 3.3e-15 1.1e-15 3.8e-16 2.3e-16
23 Adipose alternative polyA NM_001108218.1 0.13 0.07 2.8e-11 0.09 0.09 0.08 0.09 3.5e-10 6.1e-10 1.6e-09 1.5e-10
24 Adipose alternative polyA XM_039083599.1 0.14 0.07 2.4e-11 0.09 0.09 0.08 0.09 2.6e-10 5.2e-10 1.4e-09 1.4e-10
25 Adipose alternative polyA XM_039083599.1 0.16 0.09 1.9e-13 0.11 0.1 0.1 0.11 5.1e-12 1.7e-11 1.3e-11 1.9e-12
26 Adipose alternative polyA NM_001108218.1 0.16 0.08 1.2e-13 0.11 0.1 0.11 0.11 3.9e-12 1.1e-11 7.0e-12 1.3e-12
27 IL gene expression Hecw2 0.93 0.04 2.3e-03 -0.01 0 0.15 0.01 8.9e-01 3.2e-01 1.8e-04 2.1e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27
Bone: apparent density1.22.110.6-2.72.73.23.3-0.9-2.1-1.10.5-0.50.2-0.22.2-1.2-0.60.5-0.50.5-0.50.5-0.50.50.5-1.21.21.1-1.10.0
Area under the delay curve0.30.40.80.8-0.8-0.6-0.40.90.50.6-0.80.80.8-0.80.2-0.5-0.60.7-0.70.3-0.30.6-0.70.70.4-0.50.50.5-0.50.0
BMI with tail1.03.112.83.6-3.6-3.5-3.42.51.92.5-0.90.91.5-1.5-1.2-0.2-0.71.1-1.11.3-1.31.2-0.70.71.3-0.40.40.5-0.50.0
BMI without tail0.40.71.60.2-0.2-0.5-0.7-0.6-1.3-0.8-0.50.5-0.90.9-1.21.20.9-1.01.0-0.90.9-0.91.1-1.1-0.80.8-0.8-0.80.80.0
Body weight0.62.48.6-2.92.92.62.4-2.2-2.9-2.01.0-1.0-1.51.50.40.61.0-1.11.1-1.01.0-1.11.3-1.3-1.10.4-0.4-0.50.50.0
Weight adjusted by age0.60.62.5-0.70.70.70.90.21.3-0.0-1.61.60.5-0.60.9-0.7-0.70.3-0.30.4-0.40.4-0.60.60.5-1.01.01.0-1.00.0
Bone surface1.11.910.3-2.72.73.13.2-1.0-1.8-1.20.7-0.70.0-0.02.1-1.1-0.50.4-0.40.4-0.40.4-0.40.40.4-1.11.11.0-1.00.0
Bone volume1.52.511.5-2.82.83.33.4-0.8-2.1-0.90.3-0.30.3-0.32.6-1.5-0.90.8-0.80.8-0.80.8-0.80.80.8-1.51.51.4-1.40.0
Breakpoint value in progressive ratio session0.50.63.6-0.40.50.70.6-0.11.90.21.6-1.60.1-0.00.6-0.5-0.00.2-0.20.3-0.30.3-0.30.30.4-0.90.90.9-0.90.0
Number of licking bursts0.40.41.30.5-0.4-0.4-0.40.8-0.41.1-0.40.40.7-0.70.5-0.7-0.80.8-0.80.8-0.80.8-0.80.80.8-0.70.70.7-0.70.0
Context. condit. distance diff. score0.91.03.21.1-1.1-1.3-1.5-0.10.5-0.30.6-0.6-0.70.7-1.81.31.1-0.90.9-0.90.9-0.90.9-0.9-0.91.3-1.3-1.21.20.0
Locomotion velocity, session 10.91.04.52.1-2.1-2.0-1.91.41.70.8-0.50.50.8-0.8-0.80.0-0.30.5-0.50.5-0.50.5-0.50.50.50.1-0.0-0.00.00.0
Locomotion distance, session 10.20.31.21.0-1.0-0.9-1.00.30.2-0.11.1-1.1-0.10.1-0.70.40.4-0.20.2-0.20.2-0.20.2-0.2-0.20.4-0.4-0.40.40.0
Locomotion velocity, session 20.91.04.32.1-2.1-1.9-1.81.51.81.0-0.00.01.0-0.9-0.6-0.3-0.40.7-0.70.7-0.70.7-0.70.70.7-0.10.20.2-0.20.0
Locomotion distance, session 20.10.10.90.5-0.5-0.5-0.60.10.30.10.9-0.9-0.20.2-0.40.20.3-0.10.1-0.10.1-0.10.1-0.1-0.10.3-0.3-0.30.30.0
Locomotion velocity, session 31.31.52.9-0.50.50.2-0.0-1.3-0.8-1.31.7-1.7-1.41.4-1.11.41.4-1.41.4-1.31.3-1.41.4-1.4-1.41.3-1.3-1.31.30.0
Locomotion distance, session 30.20.20.50.1-0.1-0.2-0.2-0.3-0.2-0.50.7-0.7-0.40.4-0.50.50.5-0.40.4-0.40.4-0.50.4-0.4-0.40.5-0.5-0.50.50.0
Stereotopy head waving bouts, day 30.91.02.40.8-0.8-1.2-1.4-0.4-0.2-0.20.6-0.6-0.91.0-1.61.31.1-1.01.0-1.01.0-1.01.0-1.0-1.01.4-1.3-1.31.30.0
Stereotopy head waving duration, day 31.01.22.00.2-0.2-0.4-0.6-0.8-0.3-0.71.0-1.0-1.11.1-1.41.41.3-1.21.2-1.21.2-1.21.2-1.2-1.21.4-1.4-1.41.40.0
Locomotion velocity, session 71.21.35.22.3-2.3-2.1-2.01.71.60.9-0.50.51.1-1.1-0.6-0.3-0.60.8-0.80.8-0.80.8-0.80.80.8-0.20.30.3-0.30.0
Locomotion distance, session 70.10.20.60.7-0.7-0.6-0.50.60.80.40.3-0.30.5-0.4-0.0-0.3-0.30.4-0.40.4-0.40.4-0.40.40.4-0.20.20.3-0.30.0
Stereotopy head waving bouts, day 70.00.10.70.2-0.2-0.0-0.00.2-0.80.00.1-0.10.3-0.30.1-0.2-0.20.2-0.20.2-0.20.2-0.20.20.2-0.20.20.2-0.20.0
Stereotopy head waving duration, day 70.10.10.40.5-0.5-0.3-0.40.0-0.7-0.30.3-0.3-0.10.1-0.50.40.4-0.30.3-0.30.3-0.30.3-0.3-0.30.4-0.4-0.40.40.0
Locomotion velocity, session 81.72.04.82.2-2.2-1.7-1.52.11.21.4-1.21.21.8-1.80.1-1.0-1.21.4-1.41.4-1.41.4-1.41.41.4-0.90.91.0-1.00.0
Locomotion distance, session 80.60.92.71.4-1.4-1.5-1.60.10.4-0.21.2-1.2-0.50.5-1.51.00.9-0.60.6-0.60.6-0.60.6-0.6-0.61.0-1.0-1.01.00.0
Degree of sensitization distance0.80.81.20.2-0.20.10.20.80.40.9-0.70.71.0-1.01.0-1.1-1.01.0-1.01.0-1.01.0-1.01.01.0-1.01.01.0-1.00.0
Degree of sensitization stereotypy0.40.40.80.4-0.40.00.20.8-0.40.4-0.20.20.9-0.90.6-0.8-0.70.8-0.80.8-0.80.8-0.80.80.8-0.70.70.8-0.80.0
Conditioned locomotion1.01.26.2-2.32.32.22.2-1.1-2.5-0.60.1-0.1-0.40.41.4-0.5-0.20.0-0.00.0-0.00.0-0.00.00.0-0.60.60.5-0.60.0
Cocaine response after cond. corrected3.23.66.5-0.70.71.21.51.30.21.1-1.81.81.9-2.02.6-2.4-2.22.1-2.12.1-2.12.1-2.12.12.1-2.42.42.4-2.40.0
Cocaine response after cond. not corrected3.13.46.2-0.80.81.31.61.20.40.8-2.02.01.9-1.92.5-2.3-2.12.0-2.02.0-2.02.0-2.02.02.0-2.42.42.3-2.30.0
Cocaine response before conditioning0.20.20.70.3-0.3-0.5-0.5-0.20.6-0.3-0.20.2-0.40.4-0.80.70.5-0.50.5-0.50.5-0.50.5-0.5-0.50.6-0.6-0.60.60.0
Saline control response0.60.82.70.0-0.0-0.0-0.2-0.7-0.9-0.61.6-1.6-0.90.9-0.91.01.1-0.90.9-1.01.0-0.90.9-0.9-1.00.9-0.9-0.90.90.0
Bone: connectivity density0.61.04.1-1.61.51.92.0-0.3-1.2-0.5-0.00.00.4-0.51.7-1.1-0.70.6-0.60.6-0.60.6-0.60.60.6-1.11.01.0-1.00.0
Bone: cortical apparent density1.11.47.22.6-2.6-2.6-2.71.60.51.80.4-0.40.8-0.7-1.00.1-0.20.5-0.50.5-0.50.5-0.50.50.50.1-0.1-0.10.10.0
Bone: cortical area0.10.10.9-0.50.50.60.6-0.3-0.9-0.10.6-0.6-0.10.10.4-0.20.00.0-0.00.0-0.00.0-0.00.00.0-0.00.00.0-0.00.0
Bone: cortical porosity1.41.65.3-2.32.32.22.1-1.8-0.9-2.00.5-0.5-1.31.20.30.60.8-1.01.0-1.01.0-1.01.0-1.0-1.00.4-0.4-0.50.50.0
Bone: cortical porosity1.71.97.5-2.72.72.72.6-2.0-1.2-2.10.5-0.5-1.21.20.70.40.7-0.90.9-1.01.0-1.00.9-0.9-1.00.2-0.2-0.30.30.0
Bone: cortical thickness0.20.31.61.2-1.2-1.2-1.30.7-0.30.80.1-0.10.3-0.3-0.60.1-0.00.2-0.20.2-0.20.2-0.20.20.20.3-0.2-0.20.20.0
Bone: cortical thickness1.72.03.91.7-1.7-1.4-1.22.00.51.9-1.11.11.8-1.70.6-1.3-1.41.6-1.61.6-1.61.6-1.61.61.6-1.11.21.2-1.20.0
Bone: cortical tissue density1.11.47.42.6-2.6-2.7-2.71.60.61.80.4-0.40.8-0.7-1.10.1-0.20.5-0.50.5-0.50.5-0.50.50.50.1-0.1-0.00.10.0
Condit. Reinf. active minus inactive responses1.11.23.2-0.50.50.70.90.60.30.9-0.20.21.0-1.01.8-1.6-1.41.3-1.31.3-1.31.3-1.31.31.3-1.41.41.4-1.40.0
Condit. Reinf. active-inactive response ratio0.70.81.7-0.00.00.10.20.60.60.9-0.50.50.7-0.71.3-1.1-1.21.0-1.01.0-1.01.0-1.01.01.0-1.01.01.0-1.00.0
Condit. Reinf. active responses1.41.74.3-0.90.91.31.50.6-0.30.8-0.30.31.2-1.22.1-1.8-1.51.4-1.41.4-1.41.4-1.41.41.4-1.71.71.7-1.70.0
Condit. Reinf. inactive responses0.40.50.9-0.50.50.81.00.4-0.70.30.1-0.10.7-0.70.9-0.9-0.60.7-0.70.7-0.70.6-0.70.70.7-0.90.90.9-0.90.0
Incentive salience index mean2.12.55.5-0.50.50.91.11.00.31.3-0.70.71.5-1.52.3-2.2-1.91.8-1.81.8-1.81.8-1.81.81.8-2.02.02.0-2.00.0
Condit. Reinf. lever presses0.70.92.3-0.80.81.01.10.3-0.70.6-0.50.50.8-0.81.5-1.3-1.11.0-1.01.0-1.01.0-1.01.01.0-1.11.11.1-1.10.0
Condit. Reinf. active minus inactive responses2.63.27.5-1.61.62.32.60.5-0.00.7-1.61.61.5-1.62.7-2.2-1.91.7-1.71.7-1.71.7-1.71.71.7-2.32.32.2-2.20.0
Condit. Reinf. active-inactive response ratio2.93.05.4-0.70.71.01.41.00.21.3-2.32.31.7-1.72.3-2.1-2.01.8-1.81.8-1.81.8-1.81.81.8-2.12.12.1-2.10.0
Condit. Reinf. active responses2.33.26.2-1.01.01.72.11.00.21.1-1.21.21.9-1.92.5-2.3-1.91.9-1.91.9-1.91.9-1.91.91.9-2.42.32.3-2.30.0
Condit. Reinf. inactive responses0.30.30.80.5-0.50.00.20.80.40.40.7-0.70.9-0.90.3-0.7-0.40.6-0.60.6-0.60.6-0.60.60.6-0.70.70.7-0.70.0
Condit. Reinf. lever presses2.83.85.81.0-1.0-0.4-0.12.20.92.4-1.21.22.4-2.41.7-2.3-2.22.3-2.32.3-2.32.3-2.32.32.3-2.22.22.3-2.30.0
Condit. Reinf. lever reinforcers received2.94.17.5-0.80.81.62.01.30.21.5-1.31.32.2-2.22.7-2.7-2.22.2-2.22.2-2.22.2-2.22.22.2-2.62.62.6-2.60.0
Conditioned reinforcement - actives0.70.72.1-0.20.20.1-0.1-0.9-0.7-0.81.5-1.5-1.11.1-0.91.11.1-1.01.0-0.80.8-0.80.9-0.9-0.80.6-0.6-0.60.60.0
Conditioned reinforcement - inactives0.20.21.4-0.10.10.20.1-0.4-0.0-0.21.2-1.2-0.40.4-0.10.20.4-0.10.1-0.20.2-0.20.3-0.3-0.30.5-0.5-0.50.50.0
Conditioned locomotion0.20.21.60.3-0.3-0.1-0.10.2-0.80.51.3-1.30.3-0.20.0-0.20.00.3-0.30.1-0.10.2-0.30.30.2-0.50.50.5-0.50.0
Patch foraging indifference point 0 sec2.33.76.21.6-1.6-1.3-1.12.42.52.2-0.90.92.3-2.31.3-2.1-2.12.3-2.31.9-1.92.2-2.32.32.0-2.02.02.1-2.10.0
Patch foraging indifference point AUC0.10.10.5-0.60.60.20.3-0.10.00.2-0.70.7-0.00.00.2-0.1-0.20.1-0.10.3-0.30.30.0-0.00.3-0.40.40.4-0.40.0
Delay disc. indifference point, 0s delay0.80.85.41.7-1.7-1.5-1.51.12.31.30.6-0.60.7-0.7-0.2-0.3-0.40.6-0.60.3-0.30.6-0.60.60.3-0.20.20.2-0.20.0
Delay disc. indifference point, 16s delay0.30.30.50.5-0.6-0.4-0.30.70.20.5-0.70.70.7-0.70.3-0.5-0.60.6-0.60.5-0.50.6-0.60.60.5-0.50.60.6-0.60.0
Delay disc. indifference point, 2s delay1.92.13.71.0-1.1-0.7-0.51.71.81.9-0.90.91.7-1.71.2-1.6-1.61.7-1.71.5-1.51.7-1.71.71.5-1.41.51.5-1.50.0
Delay disc. indifference point, 24s delay0.30.31.80.4-0.4-0.6-0.6-0.1-1.3-0.3-0.10.1-0.40.3-0.70.60.4-0.40.4-0.70.7-0.40.4-0.4-0.60.6-0.6-0.60.60.0
Delay disc. indifference point, 4s delay0.50.62.51.6-1.6-1.2-1.11.11.20.7-0.60.60.8-0.9-0.4-0.2-0.40.5-0.50.2-0.20.5-0.50.50.3-0.20.20.2-0.20.0
Delay disc. indifference point, 8s delay0.10.10.7-0.00.00.00.10.1-0.4-0.2-0.80.80.1-0.10.0-0.0-0.10.1-0.1-0.20.20.0-0.10.1-0.10.00.00.00.00.0
Indifference point function ln k1.31.83.31.5-1.5-1.3-1.11.80.41.7-1.31.31.6-1.60.6-1.3-1.41.4-1.41.2-1.21.3-1.71.71.3-1.21.31.3-1.30.0
Indifference point function log k1.31.83.31.5-1.5-1.3-1.11.80.41.7-1.31.31.6-1.60.6-1.3-1.41.4-1.41.2-1.21.3-1.71.71.3-1.21.31.3-1.30.0
Patch foraging total patch changes 0 sec2.23.55.51.5-1.6-1.3-1.02.42.32.2-0.80.82.2-2.21.3-2.0-2.02.2-2.21.8-1.82.1-2.22.21.9-2.02.02.1-2.10.0
Patch foraging total patch changes 12 sec1.11.52.90.2-0.3-0.2-0.01.21.71.40.1-0.11.4-1.31.4-1.6-1.41.6-1.61.2-1.21.4-1.51.51.2-1.21.31.3-1.30.0
Patch foraging total patch changes 18 sec1.41.84.61.8-1.8-2.1-2.01.81.81.8-0.80.81.2-1.2-0.0-0.7-1.11.3-1.31.3-1.31.4-1.11.11.3-0.90.91.0-0.90.0
Patch foraging total patch changes 24 sec0.00.10.10.2-0.2-0.3-0.20.4-0.40.10.0-0.00.3-0.30.0-0.2-0.20.4-0.40.1-0.10.3-0.10.10.2-0.20.20.2-0.20.0
Patch foraging total patch changes 6 sec1.31.910.61.4-1.4-1.1-0.91.73.31.5-1.41.41.6-1.60.6-1.2-1.31.5-1.51.1-1.11.3-1.31.31.2-0.90.91.0-1.00.0
Patch foraging time to switch 0 sec1.42.24.0-0.20.10.1-0.2-1.31.0-1.61.8-1.8-1.61.6-1.21.51.6-1.41.4-1.61.6-1.61.5-1.5-1.72.0-2.0-2.02.00.0
Patch foraging water rate 0 sec0.30.51.6-0.10.10.30.40.5-0.40.7-0.80.80.7-0.70.5-0.7-0.60.5-0.50.9-0.90.8-0.50.50.9-1.31.31.3-1.30.0
Patch foraging water rate 12 sec2.94.46.71.5-1.4-0.7-0.32.4-0.62.6-1.81.82.6-2.61.7-2.3-2.32.3-2.32.6-2.62.3-2.32.32.5-2.32.32.3-2.30.0
Patch foraging water rate 18 sec0.81.11.9-0.10.20.71.00.8-1.40.9-0.70.71.3-1.31.2-1.3-1.11.2-1.21.2-1.21.1-1.01.01.2-1.21.21.2-1.20.0
Patch foraging water rate 24 sec0.10.10.3-0.0-0.00.20.1-0.4-0.5-0.40.1-0.1-0.40.4-0.30.50.4-0.40.4-0.40.4-0.50.5-0.5-0.40.3-0.3-0.30.30.0
Patch foraging water rate 6 sec0.30.55.00.3-0.20.10.30.6-2.20.6-0.70.70.8-0.80.1-0.5-0.40.5-0.50.9-0.90.6-0.30.30.8-0.60.60.6-0.60.0
Seeking ratio, delayed vs. immediate footshock0.40.42.2-0.90.91.41.5-0.3-0.9-0.50.3-0.30.2-0.20.8-0.4-0.20.3-0.30.1-0.10.2-0.30.30.2-0.90.90.9-0.90.0
Distance traveled before self-admin0.70.73.0-1.41.31.71.7-0.40.6-0.60.2-0.20.2-0.21.3-0.8-0.50.4-0.40.3-0.30.3-0.40.40.4-1.21.11.1-1.10.0
Distance traveled after self-admin0.20.20.60.2-0.2-0.2-0.10.50.10.6-0.20.20.5-0.50.3-0.5-0.50.5-0.50.6-0.60.6-0.50.50.6-0.80.80.8-0.80.0
Extensor digitorum longus weight0.83.29.22.7-2.6-2.8-3.00.21.40.01.4-1.4-0.90.9-3.02.11.8-1.41.4-1.41.4-1.41.4-1.4-1.42.1-2.0-2.02.00.0
Bone: elastic displacement0.91.02.50.3-0.3-0.2-0.01.00.01.3-1.61.61.1-1.10.9-1.1-1.21.1-1.11.1-1.11.1-1.11.11.1-1.11.11.1-1.10.0
Bone: elastic work0.70.82.7-1.51.51.61.7-0.3-1.4-0.0-0.30.30.2-0.31.6-0.9-0.70.6-0.60.6-0.60.6-0.60.60.6-1.01.01.0-1.00.0
Bone: endosteal estimation1.02.312.0-3.23.23.43.5-1.5-1.2-1.10.7-0.7-0.40.42.2-1.0-0.40.2-0.20.2-0.20.2-0.20.20.2-1.01.00.9-0.90.0
Bone: endosteal perimeter0.71.58.6-2.72.72.92.9-1.3-1.0-1.20.2-0.2-0.40.41.7-0.7-0.20.0-0.00.0-0.00.0-0.00.00.0-0.70.60.6-0.60.0
Epididymis fat weight1.33.110.5-3.23.22.72.5-2.5-3.0-2.10.3-0.3-1.91.80.20.91.3-1.51.5-1.41.4-1.61.6-1.6-1.30.3-0.4-0.40.40.0
Delta time in closed arm before/after self-admin0.80.82.00.7-0.7-0.9-1.0-0.30.3-0.3-0.10.1-0.80.7-1.41.20.9-0.90.9-0.80.8-0.81.1-1.1-0.81.2-1.2-1.11.10.0
Delta time in open arm before/after self-admin1.61.55.5-2.02.02.22.3-0.20.1-0.2-1.01.00.6-0.72.3-1.5-1.20.9-0.90.9-0.90.8-1.01.00.8-1.11.01.0-1.00.0
Diff in mean of infusions in LGA sessions0.60.72.1-0.20.30.50.50.51.40.50.7-0.70.7-0.71.2-1.1-0.80.9-0.90.9-0.90.9-0.90.90.9-0.90.90.9-0.90.0
Delay discount exponential model param0.30.40.7-0.70.70.40.3-0.8-0.3-0.50.8-0.8-0.80.8-0.30.60.6-0.70.7-0.30.3-0.70.7-0.7-0.40.5-0.5-0.50.50.0
Extinction: sum of active levers before priming0.70.73.1-1.51.51.61.6-0.8-1.7-0.51.3-1.3-0.30.40.8-0.30.2-0.20.2-0.20.2-0.20.1-0.1-0.1-0.50.50.5-0.50.0
Active lever presses in extinction session 60.50.51.6-1.11.11.31.2-0.30.5-0.11.0-1.00.1-0.11.2-0.8-0.30.3-0.30.2-0.20.3-0.50.50.3-0.70.70.7-0.70.0
Bone: final force1.62.56.6-2.62.62.42.2-2.3-1.6-1.72.1-2.1-1.71.70.20.81.3-1.31.3-1.31.3-1.31.3-1.3-1.30.8-0.9-0.90.90.0
Bone: final moment1.52.45.7-2.42.42.22.0-2.2-1.4-1.62.0-2.0-1.71.70.10.91.3-1.41.4-1.41.4-1.41.4-1.4-1.40.9-1.0-1.01.00.0
Food consumed during 24 hour testing period0.40.42.4-0.50.50.60.5-0.7-1.5-0.51.5-1.5-0.50.6-0.10.30.6-0.50.5-0.40.4-0.50.5-0.5-0.40.3-0.3-0.40.40.0
Glucose2.43.77.0-0.60.60.3-0.1-1.9-1.1-1.62.6-2.6-2.12.1-1.82.12.3-2.12.1-2.12.1-2.12.1-2.1-2.12.2-2.2-2.22.20.0
Heart weight0.50.71.70.4-0.30.10.20.8-0.21.00.6-0.61.0-1.00.9-1.1-0.91.0-1.01.2-1.21.3-0.90.91.0-0.80.80.8-0.80.0
Delay discount hyperbolic model param0.40.51.0-0.91.00.70.5-1.0-0.5-0.70.9-0.9-0.90.9-0.20.50.7-0.70.7-0.40.4-0.70.7-0.7-0.50.5-0.5-0.50.50.0
Intermittent access intake day 1-15 change0.20.21.20.2-0.2-0.2-0.3-0.2-1.1-0.20.8-0.8-0.30.4-0.70.50.6-0.20.2-0.50.5-0.30.5-0.5-0.40.2-0.2-0.20.20.0
Intermittent access intake escalation0.10.10.80.2-0.2-0.2-0.2-0.1-0.9-0.20.3-0.3-0.20.2-0.70.40.5-0.10.1-0.30.3-0.20.4-0.4-0.30.4-0.4-0.40.40.0
Intermittent access intake escalation 20.20.20.9-0.60.60.50.5-0.4-1.0-0.5-0.20.2-0.20.2-0.10.20.3-0.30.3-0.50.5-0.40.3-0.3-0.3-0.20.20.2-0.20.0
Intermitt. access day 1 inactive lever presses0.60.73.10.5-0.6-0.5-0.8-0.5-0.8-0.01.8-1.8-0.80.8-0.80.90.9-0.60.6-0.50.5-0.50.8-0.8-0.60.9-0.9-0.90.90.0
Intermitt. access day 15 inactive lever presses0.00.00.10.0-0.1-0.2-0.2-0.10.0-0.1-0.20.2-0.10.1-0.20.20.10.1-0.1-0.10.1-0.10.2-0.2-0.10.2-0.2-0.20.20.0
Intermitt. access escalation Index1.71.52.8-1.41.31.11.0-1.7-0.8-1.6-0.60.6-1.51.4-0.91.31.4-1.41.4-1.21.2-1.41.5-1.5-1.21.2-1.2-1.21.20.0
Intermittent access day 1 total infusions1.01.25.8-1.71.71.91.7-1.4-1.0-0.82.4-2.4-0.91.00.70.10.6-0.70.7-0.50.5-0.40.5-0.5-0.50.0-0.0-0.10.10.0
Intermittent access day 15 total infusions1.21.45.7-1.41.41.51.3-1.5-1.9-1.02.4-2.4-1.11.2-0.10.61.1-0.90.9-0.80.8-0.80.9-0.9-0.80.3-0.3-0.30.30.0
Intermittent access terminal intake (last 3 days)0.70.83.9-1.21.21.31.1-1.0-1.7-0.52.0-2.0-0.70.80.20.20.7-0.50.5-0.50.5-0.40.5-0.5-0.4-0.00.0-0.00.00.0
Intermittent access total infusions1.21.45.7-1.81.81.91.7-1.5-1.3-0.92.4-2.4-1.11.10.40.30.9-0.80.8-0.80.8-0.60.7-0.7-0.70.1-0.1-0.20.20.0
Intermittent access day 1 locomotion0.20.32.7-0.20.20.50.4-0.3-0.80.11.6-1.6-0.20.20.2-0.10.2-0.20.20.0-0.00.00.0-0.00.0-0.10.10.1-0.10.0
Intermittent access day 15 total locomotion0.60.64.3-1.01.01.21.2-0.5-2.1-0.51.7-1.7-0.10.20.5-0.30.2-0.00.0-0.30.3-0.10.0-0.0-0.2-0.50.50.5-0.50.0
Intermittent access total locomotion0.50.63.6-0.70.81.00.9-0.7-1.6-0.61.9-1.9-0.50.50.00.20.6-0.50.5-0.60.6-0.40.4-0.4-0.5-0.10.10.0-0.00.0
Intermittent access standard deviation0.90.97.3-0.90.90.50.4-0.8-2.7-0.61.9-1.9-0.70.8-0.40.40.8-0.70.7-1.01.0-0.80.7-0.7-0.80.2-0.2-0.20.20.0
Left kidney weight0.20.45.4-1.11.21.01.0-0.3-2.30.10.1-0.10.1-0.10.8-0.6-0.40.2-0.20.3-0.30.4-0.30.30.2-0.0-0.0-0.10.00.0
Right kidney weight0.20.53.0-1.01.00.90.9-0.0-1.70.21.0-1.00.3-0.31.1-0.9-0.50.5-0.50.5-0.50.6-0.60.60.4-0.40.40.4-0.40.0
Cocaine induced anxiety0.20.21.10.5-0.5-0.4-0.30.40.10.4-1.01.00.3-0.3-0.30.0-0.10.3-0.30.5-0.50.50.1-0.10.30.3-0.4-0.40.30.0
Post-drug Anxiety0.60.71.70.8-0.8-0.5-0.31.01.01.0-1.31.31.0-1.00.2-0.6-0.80.8-0.81.1-1.11.1-0.50.51.0-0.50.50.5-0.50.0
Baseline Anxiety0.10.10.5-0.40.30.30.30.10.50.0-0.00.00.2-0.20.5-0.4-0.30.2-0.20.1-0.10.1-0.50.50.2-0.70.70.7-0.70.0
Tail length4.914.748.1-6.96.96.25.8-5.6-5.8-5.41.6-1.6-4.14.00.91.82.5-3.23.2-3.33.3-3.22.9-2.9-3.21.3-1.4-1.51.50.0
Length with tail4.114.954.8-7.47.46.96.6-5.4-6.0-5.32.0-2.0-3.63.51.51.22.2-2.82.8-2.92.9-2.72.5-2.5-2.91.0-1.2-1.31.30.0
Length without tail0.40.84.2-1.91.92.02.1-0.8-1.5-0.90.9-0.9-0.20.20.9-0.40.1-0.10.1-0.20.20.00.1-0.1-0.3-0.10.0-0.00.00.0
Times rat made contact with spout0.60.71.8-0.70.70.40.2-1.0-0.9-0.81.3-1.3-1.11.1-0.50.80.9-0.90.9-0.90.9-0.90.9-0.9-0.90.8-0.8-0.80.80.0
Lifetime Intake1.21.35.7-1.41.41.51.2-1.5-1.4-0.92.4-2.4-1.21.30.00.61.0-1.01.0-0.90.9-0.80.9-0.9-0.90.3-0.3-0.30.30.0
Liver weight, left0.10.11.1-0.40.30.91.00.1-0.4-0.6-0.30.30.5-0.50.3-0.4-0.10.1-0.10.1-0.10.2-0.20.20.10.0-0.0-0.00.00.0
Liver weight, right0.10.21.2-0.70.71.01.1-0.3-0.3-0.5-0.70.70.1-0.20.4-0.2-0.10.1-0.10.1-0.10.00.1-0.1-0.00.0-0.0-0.00.00.0
Locomotor activity0.00.10.20.3-0.30.30.40.30.3-0.1-0.20.20.4-0.4-0.2-0.00.10.0-0.00.3-0.30.20.1-0.10.2-0.10.10.1-0.10.0
Locomotor testing distance0.50.81.80.7-0.7-0.10.11.21.00.8-1.11.11.3-1.30.5-0.9-0.91.0-1.01.1-1.11.0-0.80.81.0-0.90.90.9-0.90.0
Locomotor testing rearing0.10.11.8-0.20.20.50.5-0.21.4-0.3-0.00.0-0.10.0-0.20.20.3-0.40.40.1-0.1-0.00.4-0.40.00.0-0.1-0.10.10.0
Locomotion in novel chamber0.30.41.21.1-1.1-1.1-1.00.81.11.10.1-0.10.6-0.5-0.2-0.2-0.30.6-0.60.5-0.50.5-0.30.30.40.1-0.1-0.00.00.0
Locomotion in novel chamber post-restriction0.20.31.60.9-0.9-1.3-1.30.40.30.5-0.60.6-0.10.1-0.80.40.2-0.20.2-0.20.2-0.2-0.00.0-0.20.5-0.4-0.40.40.0
Fecal boli incidents, locomotor time 11.31.42.5-0.40.40.71.00.90.60.4-1.61.61.3-1.41.3-1.4-1.31.2-1.21.4-1.41.2-1.21.21.3-1.51.51.5-1.50.0
Change in fecal boli incidents, locomotor task0.10.10.50.1-0.1-0.0-0.0-0.2-0.7-0.1-0.50.5-0.30.2-0.40.40.3-0.40.4-0.40.4-0.40.4-0.4-0.20.00.00.0-0.00.0
Time >=10cm from walls, locomotor time 14.44.46.91.5-1.6-0.9-0.52.52.22.1-2.62.62.6-2.61.8-2.3-2.52.4-2.42.2-2.22.5-2.42.42.1-1.81.81.8-1.80.0
Bouts of movement, locomotor time 10.40.50.80.2-0.2-0.00.10.70.20.4-0.80.80.9-0.90.7-0.8-0.90.8-0.80.4-0.40.8-0.80.80.5-0.90.90.9-0.90.0
Total resting periods, locomotor time 10.91.01.40.8-0.8-0.7-0.51.20.81.0-1.01.01.1-1.10.7-1.0-1.21.1-1.10.7-0.71.1-1.11.10.9-1.11.11.1-1.10.0
Rest time, locomotor task time 10.20.32.1-0.20.20.1-0.1-0.41.3-0.11.5-1.5-0.50.50.00.10.3-0.20.2-0.30.3-0.20.2-0.2-0.30.2-0.2-0.20.20.0
Distance moved, locomotor task time 10.60.73.20.4-0.4-0.10.10.90.10.7-1.81.81.0-1.00.6-0.7-0.90.8-0.81.1-1.10.8-0.80.81.0-0.50.50.5-0.50.0
Vertical activity count, locomotor time 10.50.51.50.9-0.9-0.9-0.90.00.5-0.4-0.80.8-0.30.3-1.21.00.6-0.70.7-0.60.6-0.70.7-0.7-0.60.8-0.8-0.80.80.0
Time >=10cm from walls, locomotor time 23.43.67.5-0.40.30.71.01.51.21.8-1.21.22.0-2.12.7-2.6-2.42.3-2.32.3-2.32.3-2.32.32.2-2.02.02.0-2.00.0
Bouts of movement, locomotor time 21.81.93.51.5-1.5-1.0-0.81.90.51.8-0.40.41.8-1.80.8-1.4-1.41.6-1.61.5-1.51.6-1.61.61.5-1.31.31.4-1.40.0
Total resting periods, locomotor time 21.82.03.61.4-1.4-1.0-0.71.90.41.8-0.30.31.8-1.80.9-1.5-1.51.6-1.61.6-1.61.7-1.61.61.6-1.31.31.4-1.40.0
Rest time, locomotor task time 20.50.61.10.1-0.0-0.3-0.4-0.60.5-0.60.6-0.6-0.80.8-0.70.90.8-0.80.8-1.11.1-0.70.8-0.8-1.01.1-1.0-1.01.00.0
Distance moved, locomotor task time 21.01.22.60.1-0.20.00.31.10.11.1-1.31.31.3-1.31.2-1.3-1.41.3-1.31.6-1.61.3-1.31.31.4-0.90.90.8-0.90.0
Vertical activity count, locomotor time 20.30.30.80.8-0.9-0.6-0.60.70.80.70.1-0.10.6-0.60.1-0.4-0.40.5-0.50.7-0.70.5-0.50.50.7-0.60.60.6-0.60.0
Light reinforcement 10.30.65.00.1-0.1-0.4-0.6-0.2-1.40.42.2-2.2-0.40.5-0.50.30.6-0.30.3-0.30.3-0.30.3-0.3-0.30.3-0.3-0.30.30.0
Light reinforcement 20.91.33.0-1.01.01.21.20.2-1.40.81.6-1.60.7-0.61.7-1.4-1.01.1-1.11.1-1.10.9-1.21.21.0-1.21.21.2-1.20.0
Bone: marrow area1.02.111.2-3.13.13.33.3-1.4-1.2-1.00.7-0.7-0.40.32.2-1.0-0.40.2-0.20.2-0.20.2-0.20.20.2-1.01.00.9-0.90.0
Bone: maximum diameter0.10.21.1-0.60.61.01.1-0.1-0.1-0.40.1-0.10.3-0.30.7-0.5-0.30.3-0.30.3-0.30.3-0.30.30.3-0.40.40.4-0.40.0
Bone: maximum force1.52.69.6-3.13.12.92.7-2.3-2.2-1.61.6-1.6-1.51.50.90.30.9-1.01.0-1.01.0-1.01.0-1.0-1.00.3-0.4-0.40.40.0
Bone: maximum moment1.42.48.6-2.92.92.72.5-2.3-2.1-1.51.7-1.7-1.61.60.70.40.9-1.11.1-1.11.1-1.11.1-1.1-1.10.5-0.5-0.50.50.0
Mean time between licks in bursts1.01.42.30.2-0.2-0.5-0.7-0.9-0.3-0.91.3-1.3-1.31.3-1.51.51.4-1.31.3-1.31.3-1.31.3-1.3-1.31.5-1.5-1.51.50.0
Mean num. licks in bursts0.60.71.4-0.60.50.50.3-1.0-0.2-1.21.0-1.0-1.01.0-0.60.81.0-0.90.9-0.90.9-0.90.9-0.9-0.90.8-0.9-0.90.90.0
Cd content in liver2.02.23.1-0.80.80.60.4-1.6-0.7-1.81.7-1.7-1.71.7-1.31.61.7-1.71.7-1.71.7-1.71.7-1.7-1.71.6-1.6-1.61.60.0
Co content in liver0.50.61.30.6-0.6-0.8-1.0-0.30.5-0.40.4-0.4-0.70.7-1.11.00.8-0.80.8-0.80.8-0.80.8-0.8-0.81.2-1.1-1.11.10.0
Cu content in liver0.30.30.9-0.50.50.50.60.2-0.80.4-0.40.40.4-0.41.0-0.8-0.70.6-0.60.6-0.60.6-0.60.60.6-0.70.60.6-0.60.0
Fe content in liver0.70.84.0-2.02.02.02.0-0.8-1.3-0.40.3-0.3-0.20.21.2-0.6-0.20.1-0.10.1-0.10.1-0.10.10.1-0.70.60.6-0.60.0
K content in liver0.10.10.7-0.10.1-0.00.00.1-0.40.2-0.80.80.2-0.20.3-0.2-0.40.3-0.30.3-0.30.3-0.30.30.2-0.10.10.1-0.10.0
Mg content in liver0.20.20.5-0.40.40.50.60.0-0.4-0.1-0.70.70.2-0.30.6-0.4-0.40.3-0.30.3-0.30.3-0.30.30.3-0.40.30.3-0.30.0
Mn content in liver0.40.42.11.3-1.3-1.4-1.40.60.60.7-1.01.00.2-0.2-0.70.3-0.10.0-0.00.0-0.00.0-0.00.00.00.4-0.4-0.40.40.0
Na content in liver0.90.91.6-0.10.10.50.80.9-0.50.6-0.80.81.2-1.21.1-1.3-1.01.1-1.11.1-1.11.1-1.11.11.1-1.11.11.1-1.10.0
Rb content in liver1.51.83.90.6-0.60.20.61.60.90.9-1.51.51.9-2.01.2-1.6-1.51.6-1.61.6-1.61.6-1.61.61.5-1.21.21.2-1.20.0
Se content in liver0.10.10.7-0.50.50.80.8-0.0-0.70.3-0.00.00.2-0.30.6-0.4-0.30.3-0.30.3-0.30.3-0.30.30.10.1-0.1-0.10.10.0
Sr content in liver3.73.45.5-1.51.50.80.5-2.3-1.7-1.82.0-2.0-2.32.4-1.41.92.1-2.02.0-2.02.0-2.02.0-2.0-2.01.9-1.9-1.91.90.0
Zn content in liver0.20.20.9-0.40.40.10.0-0.6-0.9-0.50.4-0.4-0.70.7-0.20.50.4-0.50.5-0.50.5-0.50.5-0.5-0.50.5-0.5-0.60.60.0
Bone: minimum diameter0.30.52.3-1.51.51.51.5-0.7-1.3-0.40.3-0.3-0.20.21.0-0.5-0.20.1-0.10.1-0.10.1-0.10.10.1-0.40.40.3-0.30.0
Time in familiar zone, hab. session 10.80.71.60.5-0.5-0.5-0.6-0.40.3-0.80.3-0.3-0.70.7-1.31.11.0-0.90.9-0.90.9-0.90.9-0.9-0.91.2-1.2-1.21.20.0
Time in novel zone, hab. session 10.70.71.5-0.40.40.40.50.5-0.30.8-0.50.50.7-0.71.2-1.0-1.00.9-0.90.9-0.90.9-0.90.90.9-1.11.11.1-1.10.0
Total zone transitions, hab. session 10.70.91.61.1-1.1-0.9-0.81.31.11.0-0.90.91.1-1.10.4-0.9-1.01.0-1.01.0-1.01.0-1.01.01.0-0.70.80.8-0.80.0
Total locomotion distance, hab. session 11.11.53.1-0.30.30.50.70.8-0.41.1-0.60.61.2-1.21.8-1.7-1.51.4-1.41.4-1.41.4-1.41.41.4-1.51.51.5-1.50.0
Locomotion velocity, hab. session 10.40.51.5-0.90.91.01.10.0-0.60.20.1-0.10.4-0.41.2-0.9-0.70.6-0.60.6-0.60.6-0.60.60.6-0.90.80.8-0.80.0
Time in familiar zone, hab. session 20.30.31.20.3-0.3-0.8-0.80.4-0.70.9-1.11.10.2-0.20.2-0.3-0.60.4-0.40.4-0.40.4-0.40.40.4-0.30.30.3-0.30.0
Time in novel zone, hab. session 20.30.31.3-0.30.30.80.7-0.50.9-0.71.2-1.2-0.30.2-0.20.30.6-0.40.4-0.40.4-0.40.4-0.4-0.50.3-0.3-0.30.30.0
Total zone transitions, hab. session 20.60.71.1-0.10.10.0-0.1-0.8-0.4-1.11.1-1.1-0.90.9-0.91.01.0-0.90.9-0.90.9-0.90.9-0.9-0.91.0-1.0-1.01.00.0
Total locomotion distance, hab. session 20.81.12.3-1.41.41.21.0-1.5-1.1-1.31.5-1.5-1.31.3-0.00.70.9-0.90.9-0.90.9-0.90.9-0.9-0.90.7-0.7-0.70.70.0
Locomotion velocity, hab. session 21.11.52.8-1.41.41.21.0-1.7-1.2-1.61.6-1.6-1.51.5-0.20.91.2-1.21.2-1.21.2-1.21.2-1.2-1.20.9-0.9-0.90.90.0
Novel to familiar place preference ratio1.41.46.0-2.52.52.42.3-1.3-1.5-0.51.6-1.6-0.60.61.7-0.7-0.20.0-0.0-0.00.00.0-0.00.0-0.0-0.60.60.5-0.50.0
Novelty place preference1.31.35.6-2.32.32.42.3-1.3-1.3-0.61.6-1.6-0.60.61.5-0.6-0.1-0.10.1-0.10.1-0.10.1-0.1-0.1-0.50.50.4-0.40.0
Time in novel zone, NPP test1.11.15.0-2.22.22.22.1-1.1-1.2-0.41.4-1.4-0.50.51.6-0.7-0.20.1-0.10.1-0.10.1-0.10.10.1-0.60.60.5-0.50.0
Total zone transitions, NPP test0.10.10.30.6-0.6-0.5-0.50.30.30.10.5-0.50.1-0.1-0.40.10.2-0.00.0-0.00.0-0.00.0-0.0-0.00.1-0.1-0.10.10.0
Total locomotion distance, NPP test0.20.20.7-0.40.40.30.30.1-0.40.60.3-0.30.2-0.20.9-0.7-0.60.5-0.50.5-0.50.5-0.50.50.5-0.70.60.6-0.60.0
Locomotion velocity, NPP test0.10.10.4-0.40.40.30.2-0.1-0.60.30.6-0.6-0.00.10.6-0.4-0.20.2-0.20.2-0.20.2-0.20.20.2-0.40.30.3-0.30.0
Intraocular pressure0.40.63.91.6-1.6-1.9-2.00.80.01.30.3-0.30.2-0.2-0.80.2-0.10.3-0.30.0-0.00.1-0.30.30.10.3-0.2-0.20.20.0
Delta distance traveled before/after self-admin0.20.20.90.7-0.6-0.9-0.90.3-1.00.60.2-0.2-0.00.1-0.60.30.2-0.10.10.1-0.10.00.1-0.10.10.2-0.2-0.20.20.0
Delta ambulatory time before/after self-admin0.20.23.30.2-0.1-0.3-0.3-0.1-1.80.40.5-0.5-0.20.2-0.50.30.3-0.30.3-0.10.1-0.20.2-0.2-0.20.4-0.4-0.40.40.0
Parametrial fat weight0.10.23.9-0.40.40.10.1-0.1-2.0-0.10.1-0.1-0.10.1-0.10.00.10.0-0.0-0.20.2-0.20.2-0.2-0.20.3-0.3-0.30.30.0
Pavlov. Cond. lever latency1.51.93.80.5-0.5-0.9-1.1-0.90.4-1.11.2-1.2-1.41.4-2.01.81.6-1.51.5-1.51.5-1.51.5-1.5-1.51.7-1.7-1.71.70.0
Pavlov. Cond. magazine entry latency1.82.44.0-0.40.40.60.91.1-0.01.4-1.81.81.6-1.62.0-1.9-1.91.7-1.71.7-1.71.7-1.71.71.7-1.81.81.8-1.80.0
Pavlov. Cond. change in total contacts3.53.76.10.2-0.20.10.41.70.22.1-1.41.42.1-2.12.4-2.5-2.42.3-2.32.3-2.32.3-2.32.32.3-2.32.32.3-2.30.0
Pavlov. Cond. index score1.41.83.9-0.70.71.01.20.7-0.71.1-1.31.31.2-1.32.0-1.8-1.61.4-1.41.4-1.41.4-1.41.41.4-1.61.61.6-1.60.0
Pavlov. Cond. latency score1.72.14.4-0.70.71.11.40.8-0.51.1-1.41.41.4-1.52.1-1.9-1.71.6-1.61.6-1.61.6-1.61.61.6-1.81.81.8-1.80.0
Pavlov. Cond. lever contacts1.31.53.6-0.70.71.01.20.6-0.71.0-0.90.91.1-1.11.9-1.7-1.41.3-1.31.3-1.31.3-1.31.31.3-1.51.51.5-1.50.0
Pavlov. Cond. magazine entry number1.41.84.30.8-0.8-0.9-1.1-0.70.7-1.11.1-1.1-1.11.2-2.11.81.7-1.51.5-1.41.4-1.41.5-1.5-1.41.7-1.7-1.61.60.0
Pavlov. Cond. intertrial magazine entries0.40.51.4-1.11.11.21.1-1.00.3-1.10.9-0.9-0.70.7-0.00.40.6-0.70.7-0.60.6-0.70.7-0.7-0.60.4-0.4-0.50.50.0
Pavlov. Cond. lever-magazine prob. diff.1.62.03.8-0.50.50.70.90.9-0.71.3-1.41.41.3-1.41.9-1.8-1.71.5-1.51.5-1.51.5-1.51.51.5-1.71.71.7-1.70.0
Pavlov. Cond. response bias1.01.23.0-0.90.90.91.00.4-1.00.8-0.90.90.8-0.81.7-1.4-1.31.1-1.11.1-1.11.1-1.11.11.1-1.31.31.3-1.30.0
Pavlov. Cond. lever latency2.02.74.5-1.31.31.00.8-2.0-1.0-2.11.3-1.3-1.91.9-1.21.71.8-1.91.9-1.91.9-1.91.9-1.9-1.91.7-1.7-1.71.70.0
Pavlov. Cond. magazine entry latency0.10.10.80.8-0.8-0.8-0.90.40.40.30.4-0.40.1-0.1-0.30.1-0.00.1-0.10.1-0.10.1-0.10.10.10.1-0.1-0.10.10.0
Pavlov. Cond. change in total contacts3.04.15.81.0-0.9-0.7-0.42.20.52.4-1.61.62.3-2.31.9-2.3-2.42.4-2.42.4-2.42.4-2.42.42.4-2.32.32.3-2.30.0
Pavlov. Cond. index score1.51.93.31.0-1.0-0.7-0.61.60.71.8-0.60.61.6-1.61.1-1.5-1.51.6-1.61.6-1.61.6-1.61.61.6-1.51.51.5-1.50.0
Pavlov. Cond. latency score1.11.42.50.8-0.8-0.6-0.41.40.41.6-0.40.41.4-1.31.0-1.3-1.31.4-1.41.4-1.41.4-1.41.41.4-1.31.31.3-1.30.0
Pavlov. Cond. lever contacts2.93.95.81.1-1.1-0.7-0.42.21.12.4-1.51.52.3-2.31.7-2.2-2.32.3-2.32.3-2.32.3-2.32.32.3-2.22.22.2-2.20.0
Pavlov. Cond. magazine entry number0.20.20.60.2-0.2-0.3-0.3-0.30.1-0.5-0.30.3-0.40.4-0.80.60.5-0.50.5-0.60.6-0.50.5-0.5-0.50.6-0.6-0.60.60.0
Pavlov. Cond. intertrial magazine entries0.00.10.20.2-0.20.10.10.30.20.3-0.20.20.4-0.40.1-0.3-0.20.2-0.20.2-0.20.2-0.20.20.2-0.20.20.2-0.20.0
Pavlov. Cond. lever-magazine prob. diff.1.62.13.51.1-1.1-0.8-0.61.71.01.9-0.80.81.7-1.71.1-1.5-1.61.7-1.71.7-1.71.7-1.71.71.7-1.51.51.5-1.50.0
Pavlov. Cond. response bias1.72.33.30.7-0.7-0.3-0.11.70.71.7-1.01.01.8-1.81.5-1.8-1.81.8-1.81.8-1.81.8-1.81.81.8-1.81.81.8-1.80.0
Time in closed arm before self-admin1.31.56.1-2.12.12.32.5-0.7-1.8-1.1-0.80.80.1-0.21.6-0.9-0.60.3-0.30.3-0.30.3-0.30.30.4-1.51.51.5-1.40.0
Time in closed arm after self-admin1.11.23.1-0.00.00.30.50.8-0.20.4-1.51.51.1-1.11.0-1.1-1.21.0-1.01.0-1.01.0-0.90.91.1-1.81.81.8-1.80.0
Time in open arm before self-admin2.22.45.81.5-1.6-1.8-2.1-0.40.50.01.7-1.7-1.21.3-2.41.91.7-1.51.5-1.41.4-1.41.3-1.3-1.41.9-1.9-1.91.90.0
Time in open arm after self-admin0.20.21.2-1.01.11.01.0-0.6-0.0-0.10.3-0.3-0.40.30.7-0.20.0-0.10.10.0-0.0-0.10.0-0.0-0.20.4-0.5-0.50.50.0
Bone: periosteal estimation0.71.47.4-2.52.52.72.7-1.2-1.3-0.90.7-0.7-0.40.31.7-0.7-0.20.1-0.10.1-0.10.1-0.10.10.1-0.70.60.6-0.60.0
Bone: periosteal perimeter0.50.84.4-1.81.82.12.1-0.8-0.9-0.60.4-0.4-0.10.11.3-0.6-0.20.1-0.10.1-0.10.1-0.10.10.1-0.60.50.5-0.50.0
Bone: post-yield work1.11.54.0-1.91.91.81.6-1.7-2.0-1.21.4-1.4-1.31.30.20.61.0-1.01.0-1.01.0-1.01.0-1.0-1.00.6-0.7-0.70.70.0
Progressive ratio test 1 active lever presses0.80.92.0-0.70.70.60.4-1.3-0.2-0.81.4-1.4-1.21.2-0.71.01.2-0.90.9-0.90.9-0.91.1-1.1-0.90.7-0.7-0.80.80.0
Progressive ratio test 1 breakpoint0.60.61.7-0.80.80.70.5-1.1-0.1-0.61.3-1.3-1.11.1-0.40.81.0-0.80.8-0.70.7-0.70.9-0.9-0.70.6-0.6-0.60.60.0
Progressive ratio test 1 inactive lever presses4.85.38.5-0.50.5-0.1-0.6-2.4-1.8-1.82.9-2.9-2.82.9-2.42.82.9-2.42.4-2.52.5-2.52.5-2.5-2.52.5-2.5-2.52.50.0
Progressive ratio test 2 active lever presses1.21.32.7-0.90.90.80.5-1.5-0.9-1.41.6-1.6-1.51.5-0.81.21.4-1.21.2-1.21.2-1.11.3-1.3-1.00.5-0.5-0.50.50.0
Progressive ratio test 2 breakpoint0.60.72.4-0.50.50.50.3-1.1-0.7-0.81.5-1.5-1.11.1-0.60.91.1-0.90.9-0.80.8-0.81.0-1.0-0.70.4-0.4-0.40.40.0
Progressive ratio test 2 inactive lever presses0.70.82.8-0.60.60.40.2-1.1-0.7-0.71.7-1.7-1.21.2-0.60.91.1-0.90.9-0.90.9-0.81.0-1.0-0.80.6-0.6-0.60.70.0
Incentive Sensitization - Responses0.60.61.5-0.70.70.80.6-1.1-0.9-1.20.6-0.6-1.01.0-0.50.80.9-0.80.8-0.70.7-0.70.9-0.9-0.70.4-0.4-0.40.40.0
Incentive Sensitization - Breakpoint0.60.61.4-0.60.70.70.6-1.1-0.9-1.20.7-0.7-1.01.0-0.50.80.9-0.80.8-0.70.7-0.70.9-0.9-0.70.4-0.4-0.40.40.0
Sum of active levers in priming session hrs 5-60.50.52.2-1.11.21.51.4-0.61.2-0.41.1-1.1-0.10.11.0-0.5-0.0-0.00.00.0-0.00.1-0.30.30.0-0.30.30.3-0.30.0
Progressive ratio0.40.51.30.6-0.6-1.0-1.2-0.3-0.1-0.10.2-0.2-0.80.8-1.00.90.7-0.80.8-0.80.8-0.70.4-0.4-0.70.9-0.9-0.90.90.0
Food seeking constrained by brief footshock0.30.41.7-0.30.3-0.1-0.1-0.4-1.2-0.6-1.31.3-0.50.4-0.50.60.3-0.60.6-0.50.5-0.50.6-0.6-0.60.7-0.7-0.70.70.0
Seeking ratio, punishment vs. effort0.20.31.4-0.80.81.01.2-0.3-0.9-0.7-0.90.90.1-0.10.3-0.2-0.1-0.00.00.1-0.10.00.3-0.3-0.0-0.10.10.0-0.00.0
Retroperitoneal fat weight0.30.93.3-1.00.91.11.0-1.1-1.1-0.81.8-1.8-0.80.9-0.50.61.1-0.80.8-0.80.8-0.81.0-1.0-0.80.7-0.7-0.70.70.0
Reaction time number correct0.30.41.41.2-1.1-0.8-0.81.00.40.80.7-0.70.8-0.8-0.0-0.5-0.40.6-0.60.5-0.50.5-0.70.70.6-0.30.30.3-0.30.0
Reaction time mean minus median2.02.76.6-2.62.52.11.8-2.4-1.0-2.11.3-1.3-2.02.00.01.11.4-1.61.6-1.81.8-1.81.4-1.4-1.81.0-1.1-1.11.10.0
Reaction time mean minus median AUC1.01.33.8-1.91.91.61.4-1.7-1.3-1.41.1-1.1-1.41.40.30.60.8-1.01.0-1.11.1-1.10.8-0.8-1.10.5-0.5-0.60.60.0
Reaction time num false alarms1.01.44.51.7-1.7-1.9-2.10.32.10.31.6-1.6-0.40.5-1.30.80.6-0.40.4-0.90.9-0.70.2-0.2-0.91.3-1.3-1.21.20.0
Reaction time num false alarms AUC1.31.85.41.8-1.8-2.0-2.30.22.10.22.0-2.0-0.60.7-1.51.10.9-0.60.6-1.11.1-0.90.5-0.5-1.11.5-1.4-1.41.40.0
Reaction time trials correct on left0.30.41.41.2-1.1-0.8-0.81.00.40.80.7-0.70.8-0.8-0.0-0.5-0.40.6-0.60.5-0.50.5-0.70.70.6-0.30.30.3-0.30.0
Reaction time trials on left0.20.41.11.1-1.0-0.7-0.70.90.30.70.8-0.80.7-0.7-0.0-0.4-0.30.5-0.50.4-0.40.4-0.70.70.5-0.20.20.3-0.30.0
Reaction time mean2.33.28.4-2.92.92.62.3-2.7-2.3-2.21.8-1.8-2.12.10.51.01.3-1.61.6-1.61.6-1.51.4-1.4-1.60.8-0.9-1.00.90.0
Reaction time mean AUC2.63.57.9-2.82.82.52.2-2.8-2.3-2.22.1-2.1-2.32.20.31.21.5-1.81.8-1.71.7-1.71.6-1.6-1.71.0-1.0-1.11.10.0
Median of all reaction times1.72.46.3-2.52.52.32.1-2.3-2.5-1.81.6-1.6-1.81.70.60.81.0-1.31.3-1.21.2-1.21.2-1.2-1.20.6-0.7-0.70.70.0
Reaction time omissions1.11.53.3-1.81.81.71.5-1.7-1.4-1.41.5-1.5-1.31.30.10.71.0-1.11.1-1.21.2-1.30.9-0.9-1.20.7-0.7-0.80.80.0
Reaction time false alarm rate0.81.13.31.0-1.0-1.4-1.6-0.21.8-0.21.2-1.2-0.80.9-1.31.00.8-0.70.7-1.11.1-0.90.7-0.7-1.11.3-1.3-1.31.30.0
Reaction time premature initiation rate4.96.512.11.7-1.6-1.6-1.12.9-0.13.2-3.53.52.9-2.91.6-2.5-2.92.6-2.62.9-2.92.9-2.72.72.9-2.72.72.7-2.70.0
Reaction time premature initiations4.46.311.22.2-2.1-1.9-1.43.20.13.3-2.62.63.0-3.01.4-2.4-2.72.6-2.62.8-2.82.8-2.82.82.9-2.52.52.5-2.50.0
Std. dev. reaction times1.72.37.7-2.82.82.52.3-2.3-1.8-1.81.2-1.2-1.71.70.60.70.9-1.31.3-1.31.3-1.31.1-1.1-1.30.6-0.6-0.70.70.0
Reaction time trials completed0.20.41.11.1-1.0-0.7-0.70.90.30.70.8-0.80.7-0.7-0.0-0.4-0.30.5-0.50.4-0.40.4-0.70.70.5-0.20.20.3-0.30.0
Reaction time trials AUC0.20.31.21.1-1.1-0.7-0.70.80.30.70.9-0.90.6-0.6-0.1-0.3-0.20.4-0.40.3-0.30.3-0.60.60.4-0.10.20.2-0.20.0
Run reversals in cocaine runway, females0.50.51.00.3-0.3-0.6-0.7-0.40.6-0.60.2-0.2-0.80.7-1.01.00.8-0.70.7-0.70.7-0.70.7-0.7-0.70.9-0.9-0.90.90.0
Run reversals in cocaine runway, males1.51.52.30.4-0.4-0.20.01.3-1.01.5-0.90.91.4-1.41.3-1.5-1.51.4-1.41.5-1.51.4-1.31.31.4-1.31.31.3-1.30.0
Latency to leave start box in cocaine runway1.11.27.32.4-2.4-2.6-2.71.21.41.40.2-0.20.4-0.3-1.30.40.10.2-0.20.2-0.20.2-0.00.00.20.4-0.3-0.30.30.0
Latency to leave start box in cocaine runway, F1.01.16.72.1-2.1-2.5-2.60.81.80.70.1-0.1-0.10.1-1.60.80.4-0.20.2-0.20.2-0.20.2-0.2-0.10.6-0.5-0.40.50.0
Latency to leave start box in cocaine runway, M0.50.52.01.0-1.0-1.1-1.11.0-0.71.40.1-0.10.7-0.70.0-0.5-0.50.7-0.70.7-0.70.7-0.40.40.7-0.20.20.2-0.20.0
Std. dev. time between licks in bursts0.30.41.91.0-1.0-1.3-1.40.3-0.50.8-0.00.0-0.20.2-0.90.60.3-0.30.3-0.30.3-0.30.3-0.3-0.30.6-0.6-0.60.60.0
Total sessions with >9 infusions0.80.91.80.1-0.1-0.3-0.6-0.90.4-0.51.3-1.3-1.21.2-1.11.21.2-1.11.1-1.01.0-1.11.0-1.0-1.01.0-1.0-1.01.00.0
Short access day 1 total inactive lever presses0.50.52.2-0.50.50.80.70.2-0.70.81.5-1.50.5-0.41.0-0.9-0.50.6-0.60.5-0.50.6-0.60.60.5-0.70.70.7-0.70.0
Short access day 10 total inactive lever presses0.10.10.4-0.10.10.0-0.0-0.20.2-0.00.6-0.6-0.20.2-0.10.10.2-0.00.0-0.10.1-0.20.1-0.1-0.20.4-0.4-0.40.40.0
Short access day 1 total infusions0.50.51.6-0.80.80.60.5-0.9-1.3-0.41.3-1.3-0.80.8-0.20.50.7-0.70.7-0.50.5-0.60.6-0.6-0.60.6-0.6-0.60.60.0
Short access day 10 total infusions0.91.04.6-1.61.61.81.6-1.0-0.6-0.52.1-2.1-0.50.61.1-0.30.2-0.30.3-0.50.5-0.20.1-0.1-0.3-0.70.70.6-0.60.0
Short access total infusions0.40.52.7-0.80.80.70.5-0.9-0.6-0.31.7-1.7-0.70.80.10.30.6-0.50.5-0.60.6-0.50.4-0.4-0.50.1-0.1-0.10.10.0
Short access day 1 locomotion0.70.72.1-0.30.30.1-0.1-1.0-0.5-0.61.5-1.5-1.11.1-0.81.01.1-0.90.9-1.01.0-0.90.8-0.8-0.90.6-0.6-0.60.60.0
Short access day 10 total locomotion0.50.51.2-0.00.10.40.40.5-0.40.61.1-1.10.8-0.70.9-1.0-0.70.8-0.80.5-0.50.6-0.90.90.6-1.01.01.0-1.00.0
Short access total locomotion0.70.82.9-0.60.70.70.5-1.0-0.5-0.91.7-1.7-1.01.0-0.40.71.0-0.80.8-1.11.1-0.90.7-0.7-1.00.6-0.6-0.60.60.0
One hour access (0.3 mA shock)0.60.83.6-1.41.41.51.4-0.7-1.3-0.31.9-1.9-0.30.40.8-0.40.1-0.10.1-0.10.1-0.2-0.00.00.0-0.70.70.7-0.60.0
Compulsive drug intake0.20.20.60.5-0.5-0.6-0.50.3-0.40.2-0.80.80.2-0.2-0.30.0-0.10.1-0.10.1-0.1-0.1-0.10.1-0.00.6-0.6-0.60.60.0
One hour access (shock baseline)1.01.25.9-1.81.82.01.9-1.1-0.7-0.62.4-2.4-0.50.60.9-0.30.4-0.30.3-0.30.3-0.00.2-0.2-0.1-0.70.70.7-0.70.0
Social response proportion1.11.16.3-1.91.92.42.5-0.7-1.2-0.60.6-0.60.1-0.11.3-0.7-0.20.2-0.20.5-0.50.40.0-0.00.5-1.21.21.1-1.10.0
Social responses0.71.03.3-1.51.51.81.8-1.2-1.8-1.01.2-1.2-0.60.6-0.20.40.9-0.70.7-0.50.5-0.51.1-1.1-0.5-0.10.10.0-0.00.0
Social time0.60.83.8-1.11.01.21.2-1.1-1.9-1.1-0.50.5-0.80.8-0.50.80.9-1.01.0-0.60.6-0.71.0-1.0-0.60.3-0.4-0.40.40.0
Soleus weight0.10.40.7-0.40.40.60.70.3-0.80.3-0.40.40.6-0.50.8-0.7-0.60.6-0.60.6-0.60.6-0.60.60.6-0.80.80.8-0.80.0
Bone: stiffness2.33.67.7-2.82.82.72.4-2.7-1.8-2.42.3-2.3-2.12.1-0.11.21.7-1.81.8-1.81.8-1.81.8-1.8-1.81.1-1.2-1.21.20.0
Tibialis anterior weight0.20.72.41.3-1.2-1.4-1.60.20.80.10.5-0.5-0.40.4-1.40.90.7-0.60.6-0.60.6-0.60.6-0.6-0.50.9-0.8-0.80.80.0
Time to tail flick, vehicle, before self-admin0.60.61.30.3-0.2-0.8-0.8-0.4-0.1-0.7-0.90.9-0.80.7-1.11.10.8-0.90.9-1.01.0-1.10.4-0.4-0.90.7-0.7-0.70.70.0
Time to tail flick, vehicle, after self-admin0.10.10.5-0.20.2-0.0-0.1-0.40.7-0.5-0.00.0-0.50.5-0.00.30.2-0.30.3-0.30.3-0.30.2-0.2-0.30.4-0.4-0.40.40.0
Time to tail flick, test, before self-admin0.20.20.50.5-0.5-0.6-0.60.50.40.50.5-0.50.4-0.30.1-0.3-0.30.4-0.40.3-0.30.2-0.70.70.3-0.40.40.4-0.40.0
Time to tail flick, test, after self-admin0.91.02.20.3-0.2-0.7-0.8-0.6-1.5-0.20.1-0.1-0.90.9-1.51.31.1-1.01.0-0.90.9-0.91.2-1.2-0.91.4-1.4-1.41.40.0
Delta time to tail flick, vehicle, before/after SA0.20.21.8-0.50.40.50.5-0.30.40.01.3-1.3-0.20.20.4-0.20.00.1-0.10.1-0.10.20.2-0.2-0.00.2-0.2-0.20.20.0
Delta time to tail flick, test, before/after SA0.30.30.90.0-0.0-0.3-0.4-0.3-0.8-0.1-0.70.7-0.50.5-0.70.70.5-0.40.4-0.30.3-0.30.9-0.9-0.40.7-0.7-0.70.70.0
Tibia length1.95.418.5-4.34.33.93.7-3.5-2.2-3.51.5-1.5-2.52.40.71.01.5-1.91.9-1.91.9-1.91.9-1.9-1.80.8-0.8-0.90.90.0
Ambulatory time before self-admin0.40.41.1-0.90.81.01.1-0.20.8-0.70.2-0.20.2-0.20.9-0.6-0.40.4-0.40.1-0.10.1-0.30.30.2-1.01.00.9-0.90.0
Ambulatory time after self-admin0.30.31.00.5-0.4-0.3-0.30.70.11.00.4-0.40.6-0.50.3-0.6-0.50.6-0.60.6-0.60.6-0.70.70.7-0.70.80.8-0.80.0
Bone: tissue strength3.73.65.8-1.71.71.20.9-2.4-1.7-2.31.8-1.8-2.32.3-1.21.92.1-2.12.1-2.12.1-2.12.1-2.1-2.11.8-1.8-1.81.80.0
Total heroin consumption0.30.33.1-0.50.60.60.4-0.40.9-0.41.8-1.8-0.30.40.3-0.00.3-0.20.2-0.10.1-0.10.1-0.1-0.0-0.30.30.3-0.30.0
Bone: trabecular number0.61.05.3-2.01.92.32.3-0.9-1.6-1.10.5-0.5-0.20.11.4-0.6-0.10.1-0.10.1-0.10.1-0.10.10.1-0.60.50.5-0.50.0
Bone: trabecular spacing0.40.52.11.3-1.3-1.3-1.20.91.50.6-1.11.10.5-0.5-0.60.1-0.20.2-0.20.3-0.30.3-0.20.20.3-0.00.00.0-0.00.0
Bone: trabecular thickness0.70.82.6-1.11.01.51.6-0.0-0.80.00.1-0.10.5-0.61.6-1.1-0.80.8-0.80.8-0.80.8-0.80.80.8-1.11.01.0-1.00.0
Bone: trabecular tissue density0.71.01.7-0.30.30.0-0.2-1.1-0.2-0.81.3-1.3-1.31.3-0.91.11.2-1.11.1-1.11.1-1.11.1-1.1-1.11.1-1.1-1.11.10.0
Water consumed over 24 hours0.20.21.20.5-0.5-0.6-0.60.5-1.10.90.1-0.10.4-0.30.3-0.4-0.50.5-0.50.5-0.50.5-0.50.50.5-0.30.30.4-0.40.0
Number of responses in last shaping day2.22.24.10.3-0.3-0.8-1.1-1.1-0.7-1.01.3-1.3-1.71.7-2.01.91.9-1.61.6-1.51.5-1.61.6-1.6-1.62.0-2.0-2.02.00.0