Hecw2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose isoform ratio XM_006244912.5 0.07 0.11 2.7e-03 0.02 0.02 0.02 0.02 3.0e-03 2.8e-03 2.5e-03 3.3e-03
2 NAcc alternative TSS NM_001108218.1 0.03 0.02 6.5e-03 0.01 0 0 0 2.6e-02 3.3e-01 2.1e-01 3.0e-01
3 Adipose intron excision ratio chr9_62982726_62986764 0.03 0.02 2.3e-03 0.01 0.02 0.01 0.01 1.8e-02 5.6e-03 9.7e-03 2.5e-02
4 RMTg gene expression Hecw2 0.45 0.16 2.0e-05 0.04 0.1 0.15 0.16 3.0e-02 1.5e-03 7.4e-05 5.6e-05
5 NAcc gene expression Hecw2 0.04 0.02 2.3e-05 0.01 0.03 0.02 0.02 7.2e-03 8.7e-05 1.3e-04 1.8e-04
6 Brain intron excision ratio chr9_62903175_62918822 0.05 0.05 2.4e-03 0.02 0.01 0.01 0.02 4.0e-03 1.9e-02 5.1e-02 7.6e-03
7 IL gene expression Hecw2 0.95 0 7.6e-04 0.02 0 -0.01 -0.01 1.1e-01 2.4e-01 8.9e-01 4.7e-01
8 Brain intron excision ratio chr9_62918931_62923401 0.06 0.06 2.7e-03 0.02 0.01 0.01 0.02 4.1e-03 2.5e-02 3.9e-02 5.3e-03
9 Adipose gene expression Hecw2 0.38 0.13 0.0e+00 0.18 0.2 0.2 0.2 8.5e-20 1.8e-21 3.0e-22 1.0e-21
10 pVTA gene expression Hecw2 0.04 0.03 9.2e-03 -0 -0 0.01 0 6.2e-01 9.1e-01 3.2e-02 1.3e-01
11 NAcc intron excision ratio chr9_62903175_62918822 0.02 0.02 5.0e-03 0.01 0 0 0 5.5e-03 2.8e-01 4.5e-02 4.4e-02
12 NAcc intron excision ratio chr9_62918931_62923401 0.02 0.02 3.8e-03 0.02 0 0.01 0.01 6.6e-04 2.7e-01 1.1e-02 9.4e-03
13 IC mRNA stability Hecw2 0.48 0.18 3.1e-10 0.17 0.24 0.19 0.22 9.5e-08 2.8e-10 2.4e-08 1.6e-09
14 PL gene expression Hecw2 0.04 0.03 2.2e-04 0.04 0.04 0.02 0.04 5.0e-05 4.1e-05 1.5e-03 6.8e-05
15 Liver gene expression Hecw2 0.2 0.1 5.6e-17 0.11 0.12 0.11 0.12 1.6e-12 2.1e-13 1.4e-12 2.6e-13
16 Brain gene expression Hecw2 0.24 0.11 0.0e+00 0.21 0.22 0.21 0.21 1.1e-19 8.1e-20 1.0e-19 1.4e-19
17 Liver isoform ratio XM_039083601.2 0.04 0.04 4.1e-03 0.01 0.02 0.02 0.01 6.1e-02 2.0e-03 3.0e-03 1.7e-02
18 Brain mRNA stability Hecw2 0.25 0.1 0.0e+00 0.21 0.24 0.24 0.25 1.8e-19 2.1e-22 1.0e-22 8.5e-23
19 BLA mRNA stability Hecw2 0.25 0.14 1.9e-07 0.15 0.16 0.13 0.15 2.0e-08 1.2e-08 1.5e-07 1.8e-08
20 Liver mRNA stability Hecw2 0.06 0.04 2.2e-05 0.02 0.01 0 0.02 1.5e-03 1.0e-02 7.8e-02 6.5e-03
21 pVTA mRNA stability Hecw2 0.15 0.08 5.0e-10 0.15 0.13 0.11 0.14 3.9e-12 9.1e-11 6.6e-09 1.5e-11
22 Adipose mRNA stability Hecw2 0.17 0.08 5.6e-16 0.1 0.1 0.09 0.09 3.2e-11 4.6e-11 2.1e-10 4.2e-10
23 Adipose alternative polyA XM_039083599.2 0.2 0.1 1.1e-16 0.13 0.12 0.13 0.13 1.8e-14 1.3e-13 6.3e-14 1.2e-14
24 Adipose alternative polyA NM_001108218.1 0.2 0.1 5.6e-17 0.14 0.13 0.13 0.14 9.0e-15 6.2e-14 1.7e-14 4.4e-15
25 NAcc mRNA stability Hecw2 0.14 0.07 0.0e+00 0.13 0.13 0.14 0.13 3.7e-19 1.9e-19 3.1e-20 9.5e-20
26 PL mRNA stability Hecw2 0.23 0.1 0.0e+00 0.2 0.19 0.19 0.21 2.5e-21 3.7e-20 1.3e-20 4.6e-22

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density1.22.010.6-2.9-2.93.33.0-0.8-0.4-0.40.4-0.42.30.4-0.4-0.70.00.50.6-1.4-1.6-0.30.4-0.40.40.8-0.9-1.0-0.9
Area under the delay curve0.40.51.40.90.8-0.7-0.50.90.90.9-0.90.90.11.2-1.2-0.60.80.80.6-0.6-0.2-0.70.7-0.40.40.6-0.6-0.6-0.4
BMI with tail0.72.214.03.73.6-3.6-2.81.4-0.3-0.30.31.2-2.00.2-0.2-0.60.50.1-0.01.01.00.00.2-0.20.20.0-0.00.50.3
BMI without tail0.30.81.90.91.2-1.2-0.9-0.4-0.6-0.60.6-0.6-1.3-0.80.80.8-0.8-1.0-1.01.41.10.9-0.90.9-0.8-0.60.61.21.0
Body weight0.62.78.4-2.9-2.92.81.6-2.5-1.2-1.21.2-2.20.6-1.01.01.5-1.8-1.6-1.40.70.61.4-1.61.6-1.6-1.01.01.21.2
Weight adjusted by age0.60.92.3-0.9-1.41.31.20.21.51.5-1.50.31.2-0.10.1-0.40.60.70.7-1.1-1.0-0.80.6-0.60.61.0-1.1-0.8-0.8
Bone surface1.01.99.3-3.0-2.93.02.7-0.8-0.6-0.60.6-0.52.30.3-0.3-0.7-0.00.40.6-1.3-1.4-0.20.3-0.30.30.7-0.8-1.0-0.8
Bone volume1.42.611.1-3.0-3.13.23.3-0.5-0.2-0.20.2-0.22.70.7-0.7-1.10.30.81.0-1.7-1.9-0.70.7-0.70.71.2-1.2-1.3-1.2
Breakpoint value in progressive ratio session0.50.61.6-0.7-1.00.91.30.1-1.2-1.21.20.30.7-0.40.4-1.10.30.50.7-0.7-0.8-0.20.5-0.40.51.2-1.2-0.6-0.6
Number of licking bursts0.30.50.90.50.0-0.40.30.90.40.4-0.40.90.40.8-0.8-1.00.80.80.8-0.6-0.7-0.80.8-0.80.80.8-0.8-0.7-0.7
Context. condit. distance diff. score1.11.34.31.11.8-1.5-2.1-0.4-0.6-0.60.6-0.5-1.5-1.21.20.9-0.8-0.9-1.01.31.51.0-0.90.9-0.9-1.11.11.31.2
Locomotion velocity, session 10.70.84.22.02.1-1.8-1.41.00.50.5-0.50.9-0.90.5-0.5-0.40.60.50.20.10.2-0.30.5-0.50.50.2-0.1-0.1-0.2
Locomotion distance, session 10.30.41.41.21.2-1.0-0.80.1-1.0-1.01.00.1-1.0-0.30.3-0.1-0.2-0.2-0.20.50.50.4-0.20.2-0.2-0.30.30.40.3
Locomotion velocity, session 20.70.84.82.22.0-1.9-1.21.20.20.2-0.21.2-0.90.4-0.4-0.80.80.70.6-0.10.0-0.50.7-0.60.70.4-0.3-0.3-0.3
Locomotion distance, session 20.10.20.90.60.7-0.5-0.30.1-0.9-0.90.90.0-0.6-0.30.3-0.1-0.1-0.2-0.10.40.30.3-0.10.1-0.1-0.20.20.20.2
Locomotion velocity, session 31.51.72.6-0.30.30.0-0.6-1.3-1.6-1.61.6-1.4-1.1-1.61.61.3-1.5-1.4-1.41.41.31.5-1.41.4-1.4-1.41.41.31.4
Locomotion distance, session 30.20.20.5-0.10.2-0.2-0.5-0.4-0.7-0.70.7-0.5-0.2-0.70.70.4-0.5-0.5-0.50.50.50.5-0.50.5-0.5-0.50.50.50.5
Stereotopy head waving bouts, day 31.11.22.50.91.6-1.4-1.6-0.4-0.6-0.60.6-0.7-1.5-0.90.91.1-0.9-1.1-1.21.51.41.0-1.01.0-1.0-1.21.21.21.1
Stereotopy head waving duration, day 31.11.42.00.51.0-0.6-1.1-0.9-1.0-1.01.0-1.0-1.4-1.21.21.2-1.2-1.3-1.31.41.31.3-1.21.2-1.2-1.31.31.31.3
Locomotion velocity, session 70.91.04.42.11.8-1.9-1.41.40.60.6-0.61.3-0.60.8-0.8-0.81.00.80.7-0.3-0.0-0.70.8-0.80.80.6-0.6-0.6-0.5
Locomotion distance, session 70.10.10.30.40.4-0.4-0.10.5-0.2-0.20.20.4-0.00.2-0.2-0.50.40.40.4-0.2-0.2-0.20.4-0.40.40.3-0.3-0.4-0.3
Stereotopy head waving bouts, day 70.20.20.70.80.4-0.3-0.10.60.10.1-0.10.7-0.00.5-0.5-0.70.50.60.5-0.4-0.4-0.40.5-0.50.50.4-0.4-0.5-0.5
Stereotopy head waving duration, day 70.20.20.60.70.8-0.4-0.8-0.2-0.3-0.30.3-0.1-0.6-0.30.30.2-0.3-0.3-0.40.30.50.4-0.30.3-0.3-0.40.40.40.4
Locomotion velocity, session 81.51.84.02.01.7-1.5-0.91.71.31.3-1.31.80.01.2-1.2-1.41.51.51.2-1.1-0.8-1.21.4-1.41.41.1-1.1-1.1-1.1
Locomotion distance, session 80.81.13.71.31.9-1.6-1.7-0.1-1.1-1.11.1-0.2-1.5-1.11.10.5-0.6-0.7-0.71.11.20.9-0.60.6-0.7-0.90.91.00.9
Degree of sensitization distance0.80.81.2-0.0-0.30.30.80.80.70.7-0.70.90.81.1-1.1-1.01.01.01.1-1.1-1.0-1.01.0-1.01.01.0-1.0-1.1-1.0
Degree of sensitization stereotypy0.40.41.00.6-0.00.10.30.60.20.2-0.20.80.30.8-0.8-1.00.70.80.7-0.9-0.8-0.60.8-0.80.80.7-0.7-0.8-0.8
Conditioned locomotion0.80.95.6-2.1-2.42.12.2-0.70.00.0-0.0-0.51.40.0-0.0-0.1-0.10.00.3-0.6-0.9-0.20.0-0.00.00.3-0.4-0.4-0.4
Cocaine response after cond. corrected3.54.26.4-1.0-1.71.52.21.42.02.0-2.01.62.52.1-2.1-1.91.92.12.1-2.5-2.5-2.12.1-2.12.12.3-2.3-2.3-2.3
Cocaine response after cond. not corrected3.54.26.8-1.2-1.91.72.21.32.02.0-2.01.52.62.0-2.0-1.91.92.12.0-2.5-2.5-2.12.0-2.02.02.2-2.2-2.3-2.2
Cocaine response before conditioning0.20.20.50.20.3-0.5-0.7-0.4-0.1-0.10.1-0.4-0.6-0.50.50.5-0.5-0.5-0.50.60.70.5-0.50.5-0.5-0.60.60.60.6
Saline control response0.60.81.6-0.30.2-0.1-0.4-0.8-1.3-1.31.3-0.9-0.8-0.90.90.8-0.9-0.9-0.90.90.91.0-0.90.9-0.9-0.90.91.00.9
Bone: connectivity density0.71.14.0-1.8-1.71.92.0-0.10.10.1-0.10.11.80.6-0.6-0.80.40.70.8-1.2-1.3-0.60.6-0.60.60.9-0.9-1.0-0.9
Bone: cortical apparent density0.91.37.82.82.6-2.6-1.91.3-0.3-0.30.31.1-1.40.4-0.4-0.70.60.40.20.50.5-0.20.4-0.40.40.1-0.00.1-0.0
Bone: cortical area0.10.10.9-0.5-0.40.50.4-0.3-0.9-0.90.9-0.20.2-0.10.1-0.2-0.2-0.1-0.0-0.1-0.10.3-0.10.1-0.1-0.00.0-0.00.0
Bone: cortical porosity0.80.94.2-2.1-1.81.81.1-1.4-0.2-0.20.2-1.30.6-0.80.80.9-0.9-0.8-0.70.20.10.6-0.80.8-0.8-0.50.50.50.5
Bone: cortical porosity1.51.67.9-2.8-2.62.61.7-1.8-0.4-0.40.4-1.61.0-0.90.91.0-1.2-0.9-0.80.10.00.8-1.01.0-1.0-0.60.60.50.6
Bone: cortical thickness0.20.31.91.41.2-1.1-1.10.3-0.4-0.40.40.3-0.9-0.10.1-0.1-0.0-0.1-0.10.40.50.2-0.10.1-0.1-0.20.20.30.3
Bone: cortical thickness1.92.24.01.71.3-1.4-0.32.01.21.2-1.22.00.41.6-1.6-1.81.81.71.6-1.2-1.1-1.51.7-1.61.71.4-1.4-1.5-1.4
Bone: cortical tissue density0.91.27.62.72.6-2.6-2.01.2-0.4-0.40.41.1-1.40.3-0.3-0.60.60.30.20.50.6-0.20.4-0.40.40.00.00.10.0
Condit. Reinf. active minus inactive responses1.31.53.4-0.7-1.00.81.81.00.20.2-0.20.91.51.2-1.2-1.51.21.31.5-1.3-1.6-1.31.3-1.21.21.4-1.4-1.4-1.4
Condit. Reinf. active-inactive response ratio0.80.91.8-0.4-0.30.21.31.10.40.4-0.40.81.10.8-0.8-1.11.01.01.2-0.8-1.2-1.11.1-1.01.01.0-1.0-1.0-1.1
Condit. Reinf. active responses1.62.04.1-1.0-1.71.52.00.80.30.3-0.31.01.91.3-1.3-1.61.21.41.7-1.8-1.8-1.41.4-1.41.31.6-1.6-1.6-1.6
Condit. Reinf. inactive responses0.40.51.2-0.4-1.10.90.60.1-0.1-0.10.10.50.80.7-0.7-0.90.50.80.8-1.1-0.8-0.50.6-0.60.60.8-0.8-0.8-0.7
Incentive salience index mean2.42.94.9-0.5-1.31.02.21.40.70.7-0.71.42.01.7-1.7-2.01.71.82.1-1.9-2.1-1.81.8-1.81.81.9-2.0-2.0-2.0
Condit. Reinf. lever presses0.81.11.9-0.4-1.10.91.40.70.60.6-0.60.81.21.2-1.2-1.21.01.11.3-1.2-1.3-1.11.0-1.01.01.2-1.2-1.3-1.2
Condit. Reinf. active minus inactive responses3.14.09.3-1.5-2.52.53.10.81.81.8-1.81.22.41.8-1.8-1.71.51.91.9-2.6-2.6-1.81.8-1.81.82.1-2.1-2.2-2.1
Condit. Reinf. active-inactive response ratio3.23.86.3-0.7-1.41.32.31.42.52.5-2.51.52.11.9-1.9-1.61.81.91.9-2.2-2.3-2.11.9-1.91.92.0-2.0-2.1-2.1
Condit. Reinf. active responses2.94.07.4-0.9-1.92.02.51.11.31.3-1.31.62.32.0-2.0-2.21.82.12.1-2.7-2.6-1.92.0-2.02.02.2-2.2-2.4-2.2
Condit. Reinf. inactive responses0.30.41.20.5-0.00.2-0.00.3-0.8-0.80.80.70.30.6-0.6-1.10.50.80.8-0.9-0.6-0.30.6-0.60.60.6-0.6-0.7-0.6
Condit. Reinf. lever presses2.73.75.90.90.1-0.21.02.11.31.3-1.32.31.42.2-2.2-2.42.22.32.2-2.1-2.1-2.12.2-2.22.22.2-2.2-2.2-2.2
Condit. Reinf. lever reinforcers received3.34.78.1-0.8-1.81.82.61.41.41.4-1.41.82.42.2-2.2-2.42.02.42.4-2.8-2.8-2.12.2-2.22.22.4-2.4-2.6-2.5
Conditioned reinforcement - actives0.81.44.6-0.40.10.0-0.7-1.0-2.0-2.02.0-0.9-0.8-2.12.10.6-1.1-1.1-1.01.10.81.3-1.00.7-0.9-0.50.51.00.9
Conditioned reinforcement - inactives0.20.31.2-0.40.2-0.2-0.0-0.1-0.9-0.90.9-0.2-0.0-1.11.10.1-0.3-0.3-0.20.40.10.4-0.3-0.0-0.1-0.50.50.20.1
Conditioned locomotion0.50.73.4-0.2-0.20.30.1-0.3-1.8-1.81.8-0.1-0.0-1.91.9-0.5-0.3-0.1-0.0-0.00.10.5-0.20.1-0.30.1-0.10.20.1
Patch foraging indifference point 0 sec1.63.06.31.30.6-1.0-0.02.30.70.7-0.72.21.21.3-1.3-2.52.22.22.3-1.8-1.3-2.02.2-1.81.82.1-2.1-1.9-1.7
Patch foraging indifference point AUC0.10.20.9-0.4-0.70.30.40.00.90.9-0.90.20.4-0.10.10.10.20.20.1-0.3-0.5-0.40.2-0.40.40.5-0.5-0.3-0.5
Delay disc. indifference point, 0s delay0.60.62.91.51.7-1.6-0.71.2-0.5-0.50.51.0-0.4-0.30.3-1.00.80.60.6-0.10.1-0.40.7-0.40.40.4-0.4-0.2-0.2
Delay disc. indifference point, 16s delay0.30.40.90.50.3-0.2-0.00.60.70.7-0.70.70.31.0-1.0-0.50.70.60.6-0.6-0.4-0.60.6-0.50.50.6-0.6-0.5-0.5
Delay disc. indifference point, 2s delay1.71.93.50.80.7-0.60.51.80.90.9-0.91.81.01.0-1.0-1.91.71.71.7-1.4-1.3-1.61.7-1.61.51.6-1.6-1.5-1.5
Delay disc. indifference point, 24s delay0.20.30.70.50.9-0.7-0.7-0.10.10.1-0.1-0.3-0.60.3-0.30.6-0.3-0.5-0.50.60.80.4-0.40.7-0.7-0.50.50.50.7
Delay disc. indifference point, 4s delay0.50.52.31.51.4-1.2-1.30.90.60.6-0.60.9-0.40.7-0.7-0.50.70.60.4-0.30.2-0.50.6-0.30.30.4-0.3-0.3-0.1
Delay disc. indifference point, 8s delay0.10.10.8-0.00.00.1-0.20.10.90.9-0.90.10.10.8-0.80.20.20.10.0-0.20.1-0.20.10.1-0.10.1-0.1-0.20.0
Indifference point function ln k1.01.83.61.60.9-1.1-0.31.71.21.2-1.21.60.41.9-1.9-1.51.61.51.4-1.1-0.8-1.51.4-1.21.21.4-1.4-1.1-1.1
Indifference point function log k1.01.83.61.60.9-1.1-0.31.71.21.2-1.21.60.41.9-1.9-1.51.61.51.4-1.1-0.8-1.51.4-1.21.21.4-1.4-1.1-1.1
Patch foraging total patch changes 0 sec1.52.86.11.30.6-1.00.12.20.50.5-0.52.21.11.2-1.2-2.52.12.12.2-1.7-1.3-1.92.1-1.81.72.1-2.1-1.9-1.7
Patch foraging total patch changes 12 sec0.81.13.1-0.3-0.40.10.61.2-0.4-0.40.41.11.5-0.00.0-1.81.31.41.6-1.3-1.0-1.21.4-1.01.01.2-1.2-1.2-1.1
Patch foraging total patch changes 18 sec0.71.13.71.71.3-1.9-1.11.60.60.6-0.61.5-0.20.7-0.7-1.01.21.00.9-0.3-0.3-1.11.0-1.11.21.0-1.0-0.9-0.9
Patch foraging total patch changes 24 sec0.00.00.1-0.0-0.1-0.0-0.20.1-0.2-0.20.20.20.20.3-0.3-0.20.10.20.2-0.20.0-0.10.2-0.00.00.3-0.3-0.3-0.0
Patch foraging total patch changes 6 sec0.81.22.41.11.1-0.9-0.31.51.31.3-1.31.40.70.1-0.1-1.41.41.41.3-1.1-0.6-1.21.4-0.90.91.0-1.0-1.1-0.9
Patch foraging time to switch 0 sec1.12.33.9-0.60.9-0.1-0.6-1.3-1.7-1.71.7-1.6-0.9-1.41.41.4-1.6-1.6-1.51.61.71.7-1.51.8-1.8-2.02.01.51.8
Patch foraging water rate 0 sec0.30.61.50.2-1.00.60.60.30.70.7-0.70.80.40.5-0.5-0.70.60.80.7-1.0-1.0-0.60.6-1.01.01.2-1.2-0.9-1.0
Patch foraging water rate 12 sec2.14.46.61.3-0.1-0.31.12.21.61.6-1.62.41.32.3-2.3-2.62.42.42.3-2.3-2.4-2.22.3-2.52.52.4-2.4-2.2-2.4
Patch foraging water rate 18 sec0.71.12.3-0.3-1.10.91.20.50.50.5-0.50.91.31.2-1.2-1.20.91.21.2-1.5-1.5-0.91.0-1.31.31.0-1.1-1.1-1.3
Patch foraging water rate 24 sec0.10.20.3-0.1-0.50.2-0.1-0.6-0.3-0.30.3-0.4-0.5-0.20.20.5-0.5-0.5-0.60.40.30.5-0.50.4-0.5-0.40.40.40.4
Patch foraging water rate 6 sec0.20.41.30.5-0.50.30.10.10.40.4-0.40.60.21.2-1.2-0.40.40.50.4-0.8-0.8-0.30.4-0.90.90.4-0.4-0.5-0.8
Seeking ratio, delayed vs. immediate footshock0.30.42.7-1.0-1.61.61.1-0.5-0.3-0.30.3-0.10.70.1-0.1-0.2-0.10.20.2-0.8-0.7-0.00.0-0.10.10.7-0.7-0.5-0.3
Distance traveled before self-admin0.50.63.9-1.3-2.01.91.7-0.8-0.5-0.50.5-0.50.4-1.01.00.0-0.4-0.1-0.0-0.5-0.60.2-0.20.2-0.10.4-0.4-0.1-0.1
Distance traveled after self-admin0.30.30.70.7-0.1-0.00.00.50.60.6-0.60.7-0.10.6-0.6-0.50.60.60.6-0.5-0.5-0.60.6-0.60.60.8-0.8-0.6-0.6
Extensor digitorum longus weight0.93.612.72.93.6-3.1-3.3-0.1-1.2-1.21.2-0.4-2.9-1.31.31.2-1.0-1.3-1.62.12.31.5-1.31.3-1.3-1.51.61.91.8
Bone: elastic displacement1.01.22.8-0.2-0.50.00.41.01.71.7-1.70.91.31.1-1.1-0.81.11.11.0-1.0-1.0-1.31.1-1.11.11.1-1.1-1.0-1.1
Bone: elastic work0.70.94.2-1.9-2.11.71.8-0.10.40.4-0.4-0.11.80.5-0.5-0.50.30.50.6-0.9-1.1-0.60.5-0.50.50.7-0.8-0.8-0.8
Bone: endosteal estimation1.02.212.2-3.5-3.33.23.2-0.9-0.5-0.50.5-0.82.40.1-0.1-0.4-0.10.20.5-1.1-1.4-0.20.2-0.20.20.7-0.7-0.8-0.7
Bone: endosteal perimeter0.71.59.3-3.0-2.52.72.5-0.9-0.6-0.60.6-0.82.00.0-0.0-0.2-0.20.10.3-0.8-1.0-0.00.0-0.00.00.4-0.4-0.6-0.5
Epididymis fat weight0.62.24.8-1.5-1.41.50.2-2.2-0.7-0.70.7-2.1-0.6-1.31.31.9-1.9-1.8-1.71.31.11.6-1.71.8-1.8-1.41.31.61.6
Delta time in closed arm before/after self-admin0.20.21.11.10.7-0.7-0.60.20.30.3-0.30.2-0.90.3-0.30.3-0.0-0.1-0.20.30.30.1-0.10.1-0.1-0.10.10.10.2
Delta time in open arm before/after self-admin1.61.66.9-2.5-2.52.42.6-0.20.90.9-0.9-0.22.10.5-0.5-0.40.40.70.7-1.3-1.5-0.80.6-0.60.60.5-0.5-1.0-0.9
Diff in mean of infusions in LGA sessions0.81.02.40.1-0.30.10.91.1-0.4-0.40.41.10.90.6-0.6-1.51.11.21.4-1.1-1.2-1.01.2-1.21.21.2-1.2-1.2-1.2
Delay discount exponential model param0.50.51.6-0.8-0.70.60.4-0.8-0.9-0.90.9-0.8-0.1-1.31.30.5-0.8-0.7-0.60.60.30.7-0.70.5-0.4-0.60.60.60.4
Extinction: sum of active levers before priming0.40.41.5-1.0-1.01.10.7-0.8-1.2-1.21.2-0.60.20.3-0.30.0-0.6-0.4-0.20.0-0.00.5-0.40.4-0.4-0.0-0.00.20.3
Active lever presses in extinction session 61.21.23.4-1.6-1.81.61.80.2-0.6-0.60.60.31.8-0.10.1-1.40.70.91.2-1.3-1.4-0.70.8-0.80.81.2-1.2-1.1-1.1
Bone: final force1.62.65.5-2.4-2.02.31.3-2.3-1.8-1.81.8-2.10.0-1.61.61.4-1.8-1.6-1.30.80.71.6-1.51.5-1.5-1.21.21.11.2
Bone: final moment1.62.65.1-2.2-1.82.11.1-2.3-1.9-1.91.9-2.1-0.1-1.71.71.4-1.9-1.6-1.40.90.81.7-1.61.6-1.6-1.31.31.21.3
Food consumed during 24 hour testing period0.40.63.0-0.3-0.60.60.5-0.8-1.7-1.71.7-0.6-0.2-0.60.6-0.0-0.7-0.5-0.40.30.20.8-0.50.5-0.5-0.50.50.50.4
Glucose1.82.86.0-0.10.2-0.1-1.0-1.6-2.5-2.52.5-1.6-1.6-1.71.71.3-1.8-1.8-1.71.71.71.9-1.71.7-1.7-1.71.71.81.7
Heart weight0.30.41.60.3-0.40.20.20.41.31.3-1.30.60.30.3-0.3-0.30.50.60.4-0.7-0.7-0.60.5-0.70.60.6-0.6-0.6-0.7
Delay discount hyperbolic model param0.50.61.8-0.8-0.80.60.4-0.9-1.0-1.01.0-0.9-0.1-1.31.30.6-0.8-0.8-0.60.60.30.7-0.70.5-0.5-0.60.60.60.5
Intermittent access intake day 1-15 change0.10.21.50.60.5-0.4-1.2-0.4-0.6-0.60.60.0-0.4-0.50.50.1-0.4-0.3-0.40.30.40.6-0.40.1-0.1-0.60.60.20.2
Intermittent access intake escalation0.10.32.40.80.8-0.7-1.5-0.3-0.5-0.50.50.1-0.5-0.50.50.1-0.4-0.3-0.40.40.50.6-0.40.1-0.1-0.50.50.20.2
Intermittent access intake escalation 20.10.10.4-0.2-0.30.4-0.6-0.7-0.2-0.20.2-0.20.0-0.10.10.2-0.4-0.3-0.4-0.00.20.4-0.30.2-0.3-0.00.00.20.2
Intermitt. access day 1 inactive lever presses0.41.34.21.52.1-1.9-1.10.2-2.0-2.02.0-0.1-1.6-0.60.6-0.0-0.6-0.8-0.71.41.10.9-0.60.5-0.5-0.60.60.90.8
Intermitt. access day 15 inactive lever presses0.10.31.20.41.1-1.0-1.00.20.60.6-0.6-0.0-0.00.8-0.80.4-0.0-0.2-0.30.50.50.1-0.20.2-0.1-0.40.40.30.3
Intermitt. access escalation Index1.11.64.2-0.7-0.50.8-0.0-1.80.90.9-0.9-1.5-0.7-0.50.52.0-1.6-1.6-1.81.31.11.3-1.71.4-1.2-1.51.51.31.2
Intermittent access day 1 total infusions0.71.14.0-1.8-1.61.51.6-0.5-2.0-2.02.0-0.51.0-1.41.4-0.6-0.2-0.00.3-0.3-0.60.2-0.0-0.10.00.2-0.2-0.2-0.3
Intermittent access day 15 total infusions0.50.74.1-0.4-0.20.3-0.3-0.5-2.0-2.02.0-0.3-0.1-1.51.5-0.2-0.6-0.4-0.20.30.10.7-0.40.1-0.2-0.10.10.20.1
Intermittent access terminal intake (last 3 days)0.50.74.2-0.4-0.30.4-0.2-0.4-2.1-2.12.1-0.10.1-1.51.5-0.6-0.4-0.20.00.0-0.00.6-0.2-0.2-0.00.1-0.10.0-0.2
Intermittent access total infusions0.91.04.8-1.2-1.00.90.6-0.5-2.2-2.22.2-0.40.5-1.81.8-0.5-0.4-0.20.1-0.0-0.20.5-0.2-0.1-0.20.1-0.10.0-0.1
Intermittent access day 1 locomotion0.40.52.2-0.6-0.70.60.60.0-1.5-1.51.5-0.00.5-0.90.9-0.70.10.20.5-0.3-0.40.00.2-0.20.20.4-0.4-0.2-0.3
Intermittent access day 15 total locomotion0.30.62.2-0.5-0.90.90.3-0.1-1.5-1.51.50.20.8-0.90.9-1.10.20.50.6-0.8-0.5-0.00.3-0.30.20.7-0.7-0.4-0.4
Intermittent access total locomotion0.50.62.8-0.2-0.40.4-0.4-0.3-1.7-1.71.7-0.10.2-1.51.5-0.6-0.10.10.2-0.30.10.30.10.1-0.20.2-0.20.00.1
Intermittent access standard deviation0.20.32.1-0.1-0.20.0-0.8-0.1-1.5-1.51.50.00.3-0.40.4-0.70.00.20.3-0.20.20.10.2-0.1-0.20.2-0.2-0.0-0.0
Left kidney weight0.10.41.2-0.7-1.00.71.10.10.90.9-0.90.11.10.7-0.7-0.30.30.40.4-0.5-0.8-0.60.3-0.50.50.2-0.2-0.4-0.6
Right kidney weight0.10.31.4-0.5-0.70.50.50.30.70.7-0.70.31.2-0.00.0-0.60.50.60.6-0.7-0.7-0.60.6-0.60.50.4-0.4-0.4-0.6
Cocaine induced anxiety0.50.84.20.90.7-0.7-1.20.12.02.0-2.00.2-0.50.6-0.61.10.0-0.1-0.50.20.4-0.1-0.2-0.1-0.0-0.70.70.10.1
Post-drug Anxiety0.60.63.01.10.7-0.7-0.9-0.11.71.7-1.70.3-0.80.6-0.60.9-0.1-0.2-0.50.20.40.1-0.4-0.1-0.1-0.60.6-0.00.0
Baseline Anxiety0.00.00.7-0.2-0.20.30.8-0.1-0.2-0.20.2-0.00.10.1-0.1-0.2-0.1-0.00.0-0.1-0.10.1-0.10.0-0.20.3-0.3-0.1-0.1
Tail length2.39.145.2-6.7-6.36.44.5-4.2-0.7-0.70.7-3.92.1-1.41.42.7-2.7-2.2-1.90.2-0.01.7-2.32.3-2.4-1.21.21.11.3
Length with tail2.912.561.1-7.8-7.47.54.9-5.0-1.2-1.21.2-4.52.7-1.91.92.8-3.2-2.5-2.10.1-0.02.0-2.62.7-2.8-1.81.71.31.5
Length without tail1.03.319.7-4.2-4.44.43.1-2.1-0.8-0.80.8-1.72.5-0.10.10.2-0.9-0.4-0.1-1.0-0.90.4-0.40.7-0.7-0.30.2-0.20.0
Times rat made contact with spout0.70.81.9-0.5-0.30.2-0.1-0.9-1.4-1.41.4-0.9-0.5-0.90.90.7-1.0-1.0-0.90.90.70.9-0.90.9-0.9-0.80.80.90.8
Lifetime Intake0.81.05.1-0.9-0.60.50.4-0.5-2.3-2.32.3-0.50.1-1.91.9-0.3-0.6-0.4-0.20.30.10.7-0.40.0-0.40.0-0.00.30.1
Liver weight, left2.33.99.3-2.5-2.12.60.7-3.0-1.5-1.51.5-2.7-0.3-1.61.62.1-2.4-2.0-2.11.01.22.2-2.22.3-2.2-1.81.71.71.9
Liver weight, right0.30.62.9-1.7-1.71.61.4-0.90.30.3-0.3-0.80.9-0.30.30.6-0.5-0.4-0.3-0.0-0.30.2-0.40.5-0.3-0.30.30.20.1
Locomotor activity0.00.00.2-0.0-0.30.4-0.4-0.40.10.1-0.10.10.10.1-0.10.0-0.10.1-0.1-0.5-0.10.2-0.0-0.10.1-0.10.1-0.2-0.1
Locomotor testing distance0.30.61.4-0.1-0.60.5-0.10.40.90.9-0.90.71.00.9-0.9-0.80.70.90.7-1.2-0.8-0.70.8-0.80.80.7-0.7-1.0-0.8
Locomotor testing rearing0.00.10.4-0.5-0.50.5-0.1-0.50.00.0-0.0-0.20.4-0.70.70.1-0.3-0.1-0.3-0.2-0.10.3-0.2-0.00.0-0.10.1-0.1-0.0
Locomotion in novel chamber0.60.82.11.40.6-1.0-0.61.20.50.5-0.51.30.21.2-1.2-1.11.01.00.9-0.7-0.6-0.90.9-1.11.10.6-0.6-0.8-0.9
Locomotion in novel chamber post-restriction0.30.41.80.81.2-1.1-1.30.10.30.3-0.3-0.1-0.90.3-0.30.6-0.2-0.4-0.50.80.90.3-0.40.5-0.5-0.50.50.60.6
Fecal boli incidents, locomotor time 11.31.93.3-0.3-1.31.10.90.71.51.5-1.51.11.51.7-1.7-1.31.21.51.4-1.8-1.5-1.41.3-1.31.31.4-1.4-1.6-1.5
Change in fecal boli incidents, locomotor task0.20.20.70.60.5-0.2-0.5-0.10.80.8-0.80.0-0.8-0.00.00.6-0.1-0.2-0.40.20.20.1-0.30.1-0.10.1-0.10.30.2
Time >=10cm from walls, locomotor time 14.04.36.71.10.6-0.60.72.62.62.6-2.62.41.32.4-2.4-2.02.52.42.2-2.1-1.7-2.42.4-2.02.01.8-1.8-2.3-2.0
Bouts of movement, locomotor time 10.50.50.90.1-0.30.10.10.70.90.9-0.90.80.80.5-0.5-0.70.90.90.8-0.9-0.6-1.00.9-0.60.60.9-0.9-0.9-0.7
Total resting periods, locomotor time 10.80.91.70.60.4-0.5-0.31.31.11.1-1.11.20.70.7-0.7-1.01.21.11.1-0.9-0.6-1.21.2-0.80.91.2-1.2-1.0-0.8
Rest time, locomotor task time 10.30.41.8-0.9-0.10.20.2-0.1-1.3-1.31.3-0.40.4-1.11.1-0.1-0.3-0.3-0.10.40.30.3-0.10.5-0.5-0.10.10.20.3
Distance moved, locomotor task time 10.60.92.60.2-0.20.20.70.61.61.6-1.60.70.61.1-1.1-0.50.80.90.7-1.0-1.1-0.90.7-1.11.20.5-0.5-0.7-1.0
Vertical activity count, locomotor time 10.20.51.10.70.9-0.7-1.0-0.40.70.7-0.7-0.4-1.10.3-0.31.1-0.5-0.6-0.90.70.80.6-0.70.5-0.5-0.80.80.70.7
Time >=10cm from walls, locomotor time 22.73.96.5-0.8-1.11.02.31.91.21.2-1.21.82.51.6-1.6-2.42.22.32.5-2.4-2.5-2.22.3-2.12.12.0-2.0-2.4-2.4
Bouts of movement, locomotor time 21.11.73.51.40.9-0.9-0.31.70.40.4-0.41.80.61.2-1.2-1.91.61.61.6-1.3-1.0-1.41.6-1.41.41.4-1.4-1.4-1.3
Total resting periods, locomotor time 21.01.73.91.40.8-0.9-0.31.80.30.3-0.31.80.71.1-1.1-2.01.61.71.6-1.3-1.0-1.41.6-1.51.51.4-1.4-1.4-1.4
Rest time, locomotor task time 20.60.71.5-0.20.5-0.4-0.8-0.5-0.6-0.60.6-0.8-0.5-1.21.20.9-0.7-0.9-0.81.01.20.8-0.81.2-1.1-1.01.00.81.1
Distance moved, locomotor task time 21.21.42.6-0.1-0.40.31.11.11.21.2-1.21.11.31.1-1.1-1.21.31.31.3-1.3-1.6-1.41.3-1.61.60.8-0.8-1.2-1.6
Vertical activity count, locomotor time 20.20.20.60.70.6-0.50.10.6-0.2-0.20.20.6-0.10.6-0.6-0.60.50.50.4-0.3-0.5-0.30.4-0.80.70.5-0.5-0.3-0.6
Light reinforcement 10.41.15.70.20.5-0.5-0.9-0.5-2.4-2.42.4-0.4-0.4-1.21.2-0.2-0.7-0.7-0.40.80.70.8-0.60.5-0.5-0.50.50.80.5
Light reinforcement 20.91.33.1-1.1-1.41.21.80.4-1.6-1.61.60.51.50.3-0.3-1.70.70.91.2-1.1-1.5-0.70.9-1.01.01.0-1.0-1.0-1.2
Bone: marrow area0.92.011.3-3.4-3.23.13.0-0.8-0.5-0.50.5-0.72.30.2-0.2-0.4-0.10.20.5-1.0-1.4-0.30.2-0.20.20.7-0.7-0.8-0.7
Bone: maximum diameter0.20.30.9-1.0-0.60.90.80.0-0.5-0.50.50.10.90.3-0.3-0.60.20.40.5-0.7-0.6-0.20.4-0.40.40.5-0.5-0.6-0.5
Bone: maximum force1.42.510.5-3.2-2.72.92.1-2.2-1.6-1.61.6-2.01.0-1.31.31.0-1.6-1.2-0.90.30.11.2-1.21.2-1.2-0.80.80.70.8
Bone: maximum moment1.32.49.1-3.0-2.52.71.8-2.1-1.7-1.71.7-1.90.9-1.31.31.0-1.5-1.2-0.90.40.21.2-1.21.2-1.2-0.80.80.80.8
Mean time between licks in bursts0.51.21.80.40.8-0.8-1.0-0.8-0.9-0.90.9-0.9-1.4-1.11.11.1-1.1-1.2-1.31.31.31.2-1.11.1-1.1-1.21.21.31.2
Mean num. licks in bursts0.50.71.1-0.6-0.10.3-0.3-1.0-1.0-1.01.0-1.0-0.5-0.90.91.0-1.0-1.0-0.90.90.81.0-0.90.9-0.9-0.90.90.90.9
Cd content in liver0.30.31.1-0.9-0.81.10.7-0.8-0.7-0.70.7-0.70.2-0.40.40.3-0.6-0.4-0.30.10.00.5-0.40.4-0.4-0.50.50.20.3
Co content in liver0.30.30.60.10.5-0.4-0.8-0.4-0.1-0.10.1-0.5-0.6-0.60.60.7-0.5-0.6-0.60.60.70.5-0.60.6-0.6-0.70.70.60.6
Cu content in liver0.30.31.5-0.8-1.20.80.90.10.30.3-0.30.10.90.4-0.4-0.40.30.40.6-0.6-0.6-0.50.4-0.40.40.5-0.5-0.5-0.5
Fe content in liver0.30.42.6-1.4-1.31.61.1-0.7-0.5-0.50.5-0.40.8-0.10.1-0.1-0.3-0.00.1-0.5-0.50.1-0.10.1-0.10.3-0.3-0.3-0.2
K content in liver0.30.31.20.20.1-0.30.10.61.11.1-1.10.50.40.5-0.5-0.30.60.50.5-0.3-0.3-0.70.5-0.50.50.3-0.3-0.4-0.5
Mg content in liver0.30.31.00.1-0.30.10.40.51.01.0-1.00.50.40.6-0.6-0.40.60.50.5-0.5-0.5-0.70.5-0.50.50.6-0.6-0.6-0.5
Mn content in liver0.50.63.21.81.3-1.7-1.20.80.90.9-0.90.6-1.00.2-0.20.10.40.1-0.00.50.5-0.30.1-0.10.1-0.10.10.20.1
Na content in liver0.60.71.5-0.3-0.60.70.80.40.30.3-0.30.71.10.9-0.9-1.00.71.00.9-1.2-1.0-0.70.9-0.90.91.0-1.0-1.0-0.9
Rb content in liver1.51.73.01.10.3-0.10.21.21.31.3-1.31.60.61.4-1.4-1.61.41.61.4-1.7-1.3-1.21.4-1.41.41.3-1.3-1.5-1.3
Se content in liver0.20.20.5-0.1-0.60.60.60.10.10.1-0.10.30.40.4-0.4-0.50.30.50.5-0.7-0.6-0.30.4-0.40.40.2-0.2-0.5-0.5
Sr content in liver2.92.54.6-2.1-1.21.10.4-2.0-1.6-1.61.6-2.1-0.0-1.71.71.7-1.8-1.8-1.61.51.21.6-1.71.7-1.7-1.61.61.51.5
Zn content in liver0.30.31.1-1.0-0.90.70.6-0.7-0.4-0.40.4-0.80.1-0.60.60.6-0.6-0.7-0.50.50.30.5-0.60.6-0.6-0.50.50.50.4
Bone: minimum diameter0.20.42.2-1.5-1.31.31.3-0.4-0.6-0.60.6-0.31.00.0-0.0-0.3-0.10.10.3-0.4-0.5-0.00.1-0.10.10.3-0.3-0.3-0.3
Time in familiar zone, hab. session 10.90.92.00.81.0-0.7-1.4-0.7-0.4-0.40.4-0.6-1.4-0.90.91.0-0.9-0.9-1.11.01.21.0-0.90.9-0.9-1.11.11.01.0
Time in novel zone, hab. session 10.80.81.9-0.9-0.90.51.30.70.50.5-0.50.61.41.0-1.0-0.90.90.91.0-0.9-1.1-1.00.9-0.90.91.0-1.0-1.0-1.0
Total zone transitions, hab. session 10.60.91.50.90.8-0.7-0.11.20.80.8-0.81.20.41.0-1.0-1.11.11.11.0-0.8-0.7-1.01.0-1.01.00.9-0.9-0.9-0.9
Total locomotion distance, hab. session 11.21.82.8-0.6-0.90.61.61.20.60.6-0.61.11.71.4-1.4-1.61.41.41.6-1.4-1.7-1.51.4-1.41.41.5-1.5-1.5-1.6
Locomotion velocity, hab. session 10.40.62.1-1.1-1.11.11.40.3-0.0-0.00.00.31.20.6-0.6-0.80.50.60.8-0.9-1.0-0.60.6-0.60.60.8-0.8-0.8-0.8
Time in familiar zone, hab. session 20.40.41.50.80.3-0.8-0.10.81.21.2-1.20.6-0.20.7-0.7-0.10.60.30.30.1-0.2-0.80.4-0.50.50.4-0.4-0.2-0.4
Time in novel zone, hab. session 20.40.41.8-1.0-0.30.80.2-0.8-1.3-1.31.3-0.70.3-0.70.70.2-0.6-0.3-0.4-0.00.20.8-0.50.5-0.5-0.40.40.30.4
Total zone transitions, hab. session 20.60.81.40.10.4-0.1-0.7-0.9-1.2-1.21.2-0.8-1.0-0.90.90.8-1.0-0.9-0.90.90.91.1-0.90.9-0.9-0.91.00.90.9
Total locomotion distance, hab. session 20.81.12.4-1.5-0.91.00.8-1.2-1.5-1.51.5-1.3-0.0-1.01.00.9-1.1-1.1-0.80.80.51.0-0.91.0-1.0-0.80.80.80.7
Locomotion velocity, hab. session 21.11.42.8-1.5-0.91.00.6-1.4-1.7-1.71.7-1.5-0.2-1.21.21.1-1.3-1.3-1.01.00.71.2-1.21.2-1.2-1.01.01.01.0
Novel to familiar place preference ratio1.51.69.1-3.0-2.62.32.8-0.7-1.5-1.51.5-0.81.8-0.20.2-0.4-0.3-0.10.4-0.4-1.00.00.00.0-0.00.3-0.4-0.3-0.4
Novelty place preference1.41.58.8-3.0-2.42.22.7-0.7-1.4-1.41.4-0.81.7-0.30.3-0.3-0.3-0.10.3-0.4-0.90.1-0.10.1-0.10.3-0.3-0.2-0.3
Time in novel zone, NPP test1.31.48.4-2.9-2.42.12.6-0.5-1.3-1.31.3-0.71.8-0.20.2-0.4-0.2-0.00.4-0.5-1.0-0.00.1-0.00.00.4-0.4-0.3-0.4
Total zone transitions, NPP test0.10.10.40.60.7-0.4-0.50.0-0.7-0.70.70.1-0.5-0.10.1-0.2-0.1-0.0-0.00.10.20.2-0.00.1-0.1-0.10.10.10.1
Total locomotion distance, NPP test0.20.31.0-0.6-0.60.31.00.4-0.4-0.40.40.30.70.4-0.4-0.70.50.40.7-0.4-0.7-0.50.5-0.50.50.6-0.6-0.5-0.6
Locomotion velocity, NPP test0.10.10.7-0.5-0.50.20.80.2-0.6-0.60.60.10.40.1-0.1-0.40.20.10.4-0.1-0.4-0.20.2-0.20.20.3-0.3-0.2-0.3
Intraocular pressure0.40.64.01.41.9-2.0-1.60.8-0.1-0.10.10.4-0.8-0.00.0-0.00.2-0.1-0.00.70.6-0.00.1-0.10.1-0.10.20.40.2
Delta distance traveled before/after self-admin0.30.31.11.01.0-1.0-0.70.70.20.2-0.20.6-0.31.0-1.0-0.40.40.30.40.10.0-0.30.4-0.40.40.3-0.3-0.2-0.3
Delta ambulatory time before/after self-admin0.20.21.00.60.5-0.5-0.50.50.00.0-0.00.40.01.0-1.0-0.50.40.30.4-0.1-0.0-0.30.3-0.40.30.2-0.2-0.2-0.3
Parametrial fat weight0.51.21.90.10.4-0.4-1.0-1.0-1.1-1.11.1-1.1-1.0-0.90.91.0-1.2-1.2-1.21.31.41.2-1.11.3-1.3-1.31.31.31.3
Pavlov. Cond. lever latency1.62.03.60.91.5-1.4-1.8-0.8-1.2-1.21.2-1.0-1.9-1.11.11.4-1.3-1.5-1.61.81.71.5-1.41.4-1.3-1.51.51.61.6
Pavlov. Cond. magazine entry latency2.33.04.0-0.5-1.20.81.81.41.81.8-1.81.51.91.7-1.7-1.71.81.81.9-1.9-2.0-2.01.8-1.81.71.9-1.9-1.8-1.9
Pavlov. Cond. change in total contacts4.04.26.4-0.1-1.00.52.02.11.31.3-1.32.02.12.1-2.1-2.42.32.32.5-2.2-2.4-2.42.3-2.32.32.4-2.4-2.4-2.4
Pavlov. Cond. index score1.72.23.6-0.8-1.51.21.91.01.31.3-1.31.11.91.3-1.3-1.41.41.51.6-1.8-1.8-1.61.4-1.41.41.6-1.6-1.6-1.6
Pavlov. Cond. latency score2.02.64.1-0.9-1.61.42.01.01.41.4-1.41.22.01.4-1.4-1.61.51.71.8-2.0-1.9-1.71.6-1.61.51.7-1.8-1.8-1.8
Pavlov. Cond. lever contacts1.72.13.5-0.7-1.31.11.81.01.01.0-1.01.11.91.2-1.2-1.61.41.51.7-1.8-1.8-1.61.5-1.51.41.6-1.6-1.7-1.7
Pavlov. Cond. magazine entry number1.72.14.01.01.5-1.1-2.0-1.1-1.1-1.11.1-1.1-1.9-1.31.31.4-1.4-1.4-1.61.61.81.6-1.41.4-1.4-1.61.61.51.6
Pavlov. Cond. intertrial magazine entries0.40.51.1-0.8-0.81.10.6-1.0-0.7-0.70.7-0.9-0.3-0.80.80.7-0.8-0.6-0.60.30.20.7-0.70.7-0.7-0.60.60.50.5
Pavlov. Cond. lever-magazine prob. diff.2.02.53.5-0.6-1.31.01.81.21.51.5-1.51.31.91.5-1.5-1.61.61.61.8-1.8-1.8-1.81.6-1.61.61.8-1.8-1.7-1.8
Pavlov. Cond. response bias1.41.83.1-0.8-1.30.91.81.01.11.1-1.11.01.71.2-1.2-1.31.31.31.5-1.4-1.6-1.61.3-1.31.31.5-1.5-1.4-1.5
Pavlov. Cond. lever latency1.92.64.1-1.1-0.60.7-0.6-2.0-1.3-1.31.3-2.0-0.8-1.81.81.9-1.9-1.8-1.71.51.61.8-1.81.9-1.9-1.81.71.71.8
Pavlov. Cond. magazine entry latency0.10.10.80.80.8-0.9-0.10.6-0.2-0.20.20.4-0.40.2-0.2-0.30.30.10.10.2-0.0-0.20.2-0.20.20.1-0.1-0.0-0.1
Pavlov. Cond. change in total contacts2.54.05.50.90.2-0.41.22.31.61.6-1.62.31.42.3-2.3-2.42.32.22.3-1.9-2.1-2.32.3-2.32.32.2-2.2-2.2-2.2
Pavlov. Cond. index score1.31.83.10.90.5-0.60.71.70.70.7-0.71.70.71.5-1.5-1.81.61.51.5-1.2-1.4-1.51.6-1.61.61.5-1.5-1.4-1.5
Pavlov. Cond. latency score1.11.42.70.80.3-0.50.81.50.60.6-0.61.50.71.4-1.4-1.61.41.41.4-1.1-1.3-1.31.4-1.41.41.4-1.3-1.3-1.4
Pavlov. Cond. lever contacts2.94.05.61.00.3-0.51.02.41.71.7-1.72.41.32.3-2.3-2.42.32.32.2-2.0-2.1-2.32.3-2.32.32.2-2.2-2.2-2.2
Pavlov. Cond. magazine entry number0.20.30.80.00.3-0.1-0.9-0.60.10.1-0.1-0.5-0.5-0.50.50.8-0.5-0.5-0.50.40.70.5-0.60.6-0.6-0.60.60.60.6
Pavlov. Cond. intertrial magazine entries0.10.10.40.40.10.2-0.10.10.10.1-0.10.40.10.3-0.3-0.40.30.50.5-0.6-0.3-0.20.3-0.30.30.3-0.3-0.4-0.3
Pavlov. Cond. lever-magazine prob. diff.1.52.03.31.00.5-0.70.71.80.90.9-0.91.80.81.6-1.6-1.81.71.61.6-1.2-1.4-1.61.6-1.71.71.5-1.5-1.5-1.6
Pavlov. Cond. response bias1.62.23.20.50.0-0.21.11.71.11.1-1.11.71.11.7-1.7-1.81.71.71.6-1.5-1.7-1.71.7-1.71.71.7-1.7-1.7-1.7
Time in closed arm before self-admin0.60.74.2-2.0-2.02.01.2-0.80.50.5-0.5-0.51.4-0.30.30.3-0.20.00.0-0.7-0.5-0.1-0.10.1-0.10.7-0.7-0.3-0.2
Time in closed arm after self-admin1.61.74.00.2-0.70.40.41.01.31.3-1.31.41.21.0-1.0-1.31.41.51.4-1.6-1.3-1.41.4-1.41.32.0-2.0-1.5-1.4
Time in open arm before self-admin2.73.08.82.42.5-2.1-2.4-0.6-1.6-1.61.6-0.7-3.0-1.21.21.1-1.3-1.5-1.52.02.11.6-1.41.4-1.4-1.61.71.81.7
Time in open arm after self-admin0.20.21.4-0.8-0.60.81.2-0.20.20.2-0.2-0.40.30.5-0.50.2-0.1-0.1-0.0-0.0-0.40.0-0.10.1-0.0-0.60.6-0.0-0.1
Bone: periosteal estimation0.61.37.3-2.7-2.52.52.4-0.7-0.7-0.70.7-0.61.80.1-0.1-0.3-0.20.10.4-0.8-1.0-0.10.1-0.10.10.5-0.5-0.6-0.5
Bone: periosteal perimeter0.50.94.8-2.2-1.82.02.0-0.5-0.8-0.80.8-0.51.50.1-0.1-0.4-0.10.20.4-0.7-0.9-0.00.2-0.10.10.4-0.4-0.6-0.4
Bone: post-yield work0.71.02.4-1.5-1.21.51.0-1.3-1.6-1.61.6-1.20.3-0.90.90.6-1.0-0.8-0.70.40.20.9-0.80.8-0.8-0.60.60.60.6
Progressive ratio test 1 active lever presses0.20.31.2-0.20.3-0.3-0.5-0.1-1.0-1.01.0-0.2-0.1-1.11.10.2-0.3-0.3-0.20.50.20.4-0.3-0.0-0.00.0-0.00.30.1
Progressive ratio test 1 breakpoint0.10.20.8-0.30.1-0.2-0.3-0.0-0.9-0.90.9-0.10.1-0.90.90.0-0.2-0.2-0.10.30.10.3-0.2-0.20.10.2-0.20.1-0.1
Progressive ratio test 1 inactive lever presses2.53.57.80.51.7-1.3-1.8-1.1-2.5-2.52.5-1.3-1.8-2.82.81.3-1.7-1.8-1.72.32.02.0-1.61.5-1.6-1.71.71.91.8
Progressive ratio test 2 active lever presses0.50.62.4-0.6-0.10.2-0.2-0.6-1.5-1.51.5-0.4-0.2-1.51.50.3-0.7-0.6-0.50.60.30.8-0.60.2-0.3-0.10.10.40.2
Progressive ratio test 2 breakpoint0.50.52.3-0.6-0.10.2-0.2-0.5-1.5-1.51.5-0.4-0.2-1.41.40.3-0.6-0.6-0.50.50.30.7-0.60.1-0.3-0.10.10.30.2
Progressive ratio test 2 inactive lever presses0.50.92.9-0.80.10.1-0.3-0.7-1.7-1.71.7-0.7-0.0-1.71.70.3-0.8-0.8-0.60.80.51.0-0.80.5-0.6-0.50.50.70.5
Incentive Sensitization - Responses0.20.20.7-0.8-0.50.60.2-0.7-0.4-0.40.4-0.5-0.0-0.70.70.7-0.6-0.5-0.50.30.20.5-0.60.2-0.4-0.20.20.30.2
Incentive Sensitization - Breakpoint0.20.30.6-0.8-0.40.60.1-0.7-0.5-0.50.5-0.5-0.1-0.80.80.7-0.6-0.6-0.60.30.30.6-0.60.3-0.4-0.20.20.30.3
Sum of active levers in priming session hrs 5-60.80.83.0-1.7-1.71.71.6-0.6-1.1-1.11.1-0.61.0-1.01.0-0.5-0.20.00.3-0.5-0.60.2-0.10.1-0.10.2-0.2-0.2-0.1
Progressive ratio0.30.52.01.11.4-1.3-0.90.30.20.2-0.2-0.1-1.4-0.20.20.6-0.2-0.5-0.61.00.90.3-0.40.6-0.5-0.50.50.70.7
Food seeking constrained by brief footshock0.30.41.70.30.2-0.3-0.7-0.21.31.3-1.3-0.2-0.7-0.40.41.0-0.2-0.4-0.50.40.60.0-0.30.4-0.4-0.60.60.40.4
Seeking ratio, punishment vs. effort0.20.31.4-1.0-1.11.20.4-0.60.80.8-0.8-0.30.80.3-0.30.4-0.10.1-0.1-0.6-0.3-0.1-0.0-0.10.0-0.10.1-0.2-0.2
Retroperitoneal fat weight0.93.86.0-0.9-0.50.8-0.5-2.5-2.4-2.42.4-2.2-1.1-2.22.21.7-2.3-2.2-2.01.81.72.3-2.12.1-2.0-2.02.02.01.9
Reaction time number correct0.20.30.90.71.0-0.8-0.40.7-0.6-0.60.60.7-0.00.1-0.1-0.90.50.60.5-0.3-0.3-0.30.5-0.50.50.4-0.4-0.3-0.4
Reaction time mean minus median1.02.46.6-2.6-1.61.81.1-1.9-1.3-1.31.3-2.20.1-1.71.71.6-1.7-1.6-1.41.11.01.4-1.51.8-1.8-1.31.31.41.5
Reaction time mean minus median AUC0.41.14.1-2.0-1.51.41.2-1.2-1.0-1.01.0-1.40.4-1.01.00.9-1.0-1.0-0.80.60.40.7-0.91.1-1.1-0.70.70.80.8
Reaction time num false alarms1.21.64.61.62.0-2.2-2.00.4-1.6-1.61.6-0.1-1.4-1.81.80.1-0.3-0.6-0.41.31.50.6-0.40.9-0.9-1.01.01.11.1
Reaction time num false alarms AUC1.42.25.51.62.1-2.3-2.30.3-2.0-2.02.0-0.3-1.6-1.91.90.2-0.5-0.8-0.61.61.80.8-0.61.1-1.1-1.21.21.31.4
Reaction time trials correct on left0.20.30.90.71.0-0.8-0.40.7-0.6-0.60.60.7-0.00.1-0.1-0.90.50.60.5-0.3-0.3-0.30.5-0.50.50.4-0.4-0.3-0.4
Reaction time trials on left0.10.30.80.60.9-0.7-0.30.6-0.7-0.70.70.6-0.00.1-0.1-0.80.50.50.4-0.3-0.3-0.20.4-0.50.50.4-0.4-0.2-0.3
Reaction time mean1.72.69.0-3.0-2.22.42.1-2.0-1.7-1.71.7-2.20.2-1.11.11.5-1.7-1.6-1.40.90.51.4-1.51.6-1.6-1.21.21.11.2
Reaction time mean AUC1.82.98.7-2.9-2.12.31.9-2.1-1.9-1.91.9-2.30.0-1.21.21.6-1.9-1.7-1.51.10.61.5-1.61.7-1.7-1.31.31.21.3
Median of all reaction times1.31.96.8-2.6-2.12.22.0-1.7-1.5-1.51.5-1.80.2-0.60.61.2-1.4-1.3-1.10.70.21.1-1.21.2-1.3-1.00.90.80.9
Reaction time omissions1.11.62.8-1.7-1.41.60.7-1.7-1.7-1.71.7-1.7-0.3-0.90.91.1-1.4-1.3-1.20.80.61.3-1.21.3-1.3-1.11.01.11.1
Reaction time false alarm rate1.01.42.91.11.4-1.6-1.70.0-1.3-1.31.3-0.4-1.3-1.71.70.5-0.5-0.8-0.71.41.50.7-0.61.0-1.0-1.11.11.11.2
Reaction time premature initiation rate4.86.611.51.60.5-1.10.32.83.43.4-3.42.81.53.1-3.1-2.32.92.72.6-2.3-2.2-2.92.6-2.82.82.7-2.7-2.4-2.6
Reaction time premature initiations3.25.78.01.81.0-1.40.12.82.52.5-2.52.81.32.8-2.8-2.52.82.72.5-2.2-2.0-2.72.6-2.82.82.6-2.6-2.2-2.5
Std. dev. reaction times1.12.08.2-2.9-2.22.31.9-1.8-1.1-1.11.1-1.90.5-0.80.81.3-1.4-1.3-1.00.60.31.0-1.21.4-1.4-0.90.90.91.0
Reaction time trials completed0.10.30.80.60.9-0.7-0.30.6-0.7-0.70.70.6-0.00.1-0.1-0.80.50.50.4-0.3-0.3-0.20.4-0.50.50.4-0.4-0.2-0.3
Reaction time trials AUC0.10.20.90.71.0-0.7-0.40.6-0.8-0.80.80.5-0.1-0.10.1-0.70.40.40.4-0.2-0.1-0.10.4-0.40.40.3-0.3-0.1-0.2
Run reversals in cocaine runway, females0.50.51.60.20.8-0.5-0.8-0.4-0.1-0.10.1-0.6-1.0-0.30.31.3-0.7-0.8-0.91.00.90.7-0.70.8-0.7-0.80.80.80.8
Run reversals in cocaine runway, males1.81.82.80.0-0.40.01.11.40.90.9-0.91.31.51.4-1.4-1.71.51.51.6-1.4-1.5-1.51.5-1.51.51.4-1.4-1.4-1.6
Latency to leave start box in cocaine runway0.91.17.22.12.7-2.6-2.01.1-0.2-0.20.20.8-1.1-0.20.2-0.30.30.0-0.00.80.7-0.00.2-0.20.2-0.00.00.40.2
Latency to leave start box in cocaine runway, F1.11.37.81.82.8-2.6-2.40.60.00.0-0.00.2-1.4-0.40.40.5-0.1-0.5-0.61.31.30.4-0.30.3-0.3-0.40.40.90.7
Latency to leave start box in cocaine runway, M0.70.72.31.51.3-1.4-0.51.30.20.2-0.21.2-0.10.7-0.7-1.10.90.80.8-0.3-0.4-0.70.9-0.90.90.4-0.4-0.5-0.7
Std. dev. time between licks in bursts0.30.42.11.01.2-1.5-1.10.3-0.1-0.10.10.1-0.8-0.20.20.2-0.1-0.3-0.30.80.70.2-0.20.2-0.2-0.40.40.60.4
Total sessions with >9 infusions0.60.73.00.20.6-0.6-0.6-0.2-1.5-1.51.5-0.4-0.6-1.71.70.0-0.5-0.6-0.40.80.50.7-0.50.3-0.3-0.30.30.70.5
Short access day 1 total inactive lever presses0.50.62.6-0.1-0.30.10.50.4-1.4-1.41.40.40.4-1.61.6-1.30.40.50.7-0.4-0.5-0.20.5-0.30.40.6-0.6-0.3-0.4
Short access day 10 total inactive lever presses0.00.10.40.30.3-0.2-0.1-0.0-0.6-0.60.6-0.0-0.1-0.10.1-0.5-0.00.00.10.00.10.1-0.0-0.00.0-0.20.20.10.1
Short access day 1 total infusions0.60.82.8-0.5-0.40.40.4-0.9-1.7-1.71.7-0.8-0.4-1.61.60.3-0.9-0.8-0.70.70.31.0-0.80.5-0.6-0.50.40.80.6
Short access day 10 total infusions0.91.15.7-1.1-0.90.81.10.0-2.4-2.42.4-0.20.6-1.61.6-1.00.00.10.5-0.2-0.50.10.3-0.20.10.8-0.8-0.0-0.3
Short access total infusions0.50.63.6-0.5-0.30.10.5-0.1-1.9-1.91.9-0.20.1-1.51.5-0.6-0.2-0.20.10.3-0.20.4-0.1-0.20.10.3-0.30.2-0.1
Short access day 1 locomotion0.50.62.3-0.10.5-0.4-0.2-0.3-1.4-1.41.4-0.5-0.5-1.51.50.3-0.6-0.7-0.60.90.60.8-0.60.4-0.6-0.30.30.70.6
Short access day 10 total locomotion0.61.24.50.80.1-0.40.11.3-0.9-0.90.91.20.70.0-0.0-2.11.31.41.5-1.2-1.0-1.01.4-1.11.11.4-1.4-0.9-1.0
Short access total locomotion0.70.83.00.50.7-0.6-0.7-0.2-1.7-1.71.7-0.3-0.8-1.61.6-0.1-0.5-0.5-0.40.70.70.8-0.50.5-0.6-0.40.40.80.6
One hour access (0.3 mA shock)0.80.93.4-1.4-1.31.20.8-0.4-1.8-1.81.8-0.30.9-1.41.4-0.8-0.10.10.4-0.5-0.60.20.2-0.20.10.7-0.7-0.1-0.3
Compulsive drug intake0.50.51.10.81.0-0.9-0.7-0.20.80.8-0.8-0.4-0.90.2-0.20.8-0.5-0.6-0.80.80.80.5-0.60.7-0.4-1.01.00.90.8
One hour access (shock baseline)1.11.64.7-1.7-1.71.51.40.0-2.2-2.22.20.31.5-1.11.1-1.40.40.71.0-1.1-1.2-0.30.6-0.90.71.3-1.3-1.0-1.1
Social response proportion1.11.27.0-1.5-2.62.52.0-0.9-0.6-0.60.6-0.01.10.3-0.3-0.5-0.10.30.3-1.2-1.5-0.00.1-0.80.70.9-0.9-0.8-1.0
Social responses0.60.73.2-0.6-1.71.80.5-1.7-1.2-1.21.2-0.6-0.2-0.60.60.5-1.1-0.6-0.7-0.2-0.11.0-0.80.3-0.3-0.10.10.20.2
Social time0.40.51.8-0.8-1.01.20.2-1.30.50.5-0.5-0.8-0.2-0.20.21.3-0.9-0.8-0.90.20.10.7-1.00.3-0.3-0.40.40.50.3
Soleus weight0.20.50.7-0.3-0.80.60.80.30.60.6-0.60.50.90.7-0.7-0.70.60.70.7-0.9-0.8-0.60.6-0.60.60.8-0.9-0.7-0.7
Bone: stiffness2.43.87.8-2.8-2.22.61.3-2.7-2.3-2.32.3-2.5-0.0-2.02.01.7-2.2-1.9-1.71.00.92.0-1.91.9-1.9-1.61.61.41.5
Tibialis anterior weight0.20.62.31.41.5-1.4-1.50.0-0.2-0.20.2-0.0-1.2-0.40.40.4-0.3-0.4-0.60.80.90.5-0.40.4-0.4-0.60.60.70.7
Time to tail flick, vehicle, before self-admin0.80.82.0-0.5-0.10.2-0.5-1.10.20.2-0.2-1.2-0.6-0.80.81.4-1.0-1.1-1.20.91.00.9-1.21.2-1.1-0.70.71.11.2
Time to tail flick, vehicle, after self-admin0.10.20.5-0.70.00.10.6-0.3-0.4-0.40.4-0.6-0.0-0.30.30.5-0.4-0.5-0.40.50.20.3-0.40.4-0.4-0.50.50.30.4
Time to tail flick, test, before self-admin0.20.20.80.50.9-0.9-0.40.7-0.4-0.40.40.50.1-0.30.3-0.60.50.40.4-0.00.0-0.30.3-0.30.30.4-0.4-0.1-0.2
Time to tail flick, test, after self-admin0.50.61.81.01.0-0.8-1.4-0.40.20.2-0.2-0.3-1.1-0.00.00.9-0.6-0.7-0.80.91.00.6-0.60.6-0.6-0.90.90.70.7
Delta time to tail flick, vehicle, before/after SA0.10.10.4-0.10.3-0.30.20.4-0.6-0.60.60.20.3-0.20.2-0.40.20.10.20.1-0.2-0.10.3-0.30.2-0.20.2-0.2-0.2
Delta time to tail flick, test, before/after SA0.10.10.50.50.2-0.2-0.4-0.20.70.7-0.7-0.0-0.40.3-0.30.5-0.2-0.3-0.30.30.20.1-0.20.1-0.1-0.40.40.20.1
Tibia length1.84.918.2-4.3-3.83.72.4-3.1-1.7-1.71.7-2.91.0-2.02.01.9-2.3-2.0-1.70.90.51.8-2.02.0-2.0-1.41.31.21.3
Ambulatory time before self-admin0.40.62.6-1.0-1.61.61.2-1.0-0.7-0.70.7-0.6-0.0-1.21.20.3-0.6-0.4-0.3-0.1-0.20.5-0.40.5-0.40.1-0.10.20.2
Ambulatory time after self-admin0.20.20.60.6-0.1-0.00.10.4-0.1-0.10.10.6-0.10.2-0.2-0.80.50.50.6-0.5-0.4-0.40.5-0.50.50.7-0.7-0.5-0.5
Bone: tissue strength3.53.55.7-1.8-1.11.2-0.1-2.4-2.0-2.02.0-2.4-0.5-2.12.12.0-2.2-2.1-1.91.61.62.0-2.12.1-2.1-1.81.81.91.9
Total heroin consumption0.70.84.7-0.8-0.70.81.3-0.3-2.2-2.22.2-0.20.3-0.90.9-0.8-0.3-0.10.2-0.1-0.40.4-0.00.1-0.10.4-0.5-0.0-0.1
Bone: trabecular number0.50.85.1-1.9-1.92.32.1-0.8-0.4-0.40.4-0.51.3-0.00.0-0.2-0.20.00.1-0.7-0.90.00.0-0.00.00.3-0.3-0.4-0.4
Bone: trabecular spacing0.30.41.21.00.8-1.1-1.00.71.01.0-1.00.6-0.30.4-0.4-0.10.50.40.3-0.10.1-0.40.4-0.40.40.2-0.2-0.2-0.2
Bone: trabecular thickness0.60.83.5-1.2-1.31.51.90.1-0.2-0.20.20.21.30.6-0.6-0.90.40.70.8-1.1-1.2-0.50.6-0.60.60.8-0.8-0.9-0.8
Bone: trabecular tissue density0.71.11.5-0.10.10.0-0.2-1.0-1.2-1.21.2-1.0-1.2-1.11.11.1-1.1-1.2-1.11.21.01.2-1.11.1-1.1-1.11.11.11.1
Water consumed over 24 hours0.10.10.60.2-0.0-0.30.30.1-0.8-0.80.80.0-0.1-0.10.1-0.3-0.0-0.10.00.30.00.1-0.00.0-0.0-0.00.00.20.0
Number of responses in last shaping day1.41.52.7-0.21.1-0.8-1.5-1.0-1.2-1.21.2-1.2-0.9-0.90.91.3-1.3-1.4-1.41.61.61.4-1.31.1-1.3-1.41.41.41.3