Hub : Genes

Hdac10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Hdac10 0.08 0.06 2.3e-06 0.04 0.04 0.05 0.04 1.7e-05 1.0e-05 2.6e-06 1.3e-05
2 NAcc intron excision ratio chr7_122080857_122081004 0.03 0.02 2.6e-04 0.03 0.02 0.03 0.03 4.9e-05 1.5e-04 9.9e-05 6.1e-05
3 Adipose mRNA stability Hdac10 0.02 0.02 4.0e-03 0.02 0.01 0.01 0.02 2.0e-03 1.0e-02 3.4e-02 6.1e-03
4 Brain intron excision ratio chr7_122080927_122081004 0.06 0.04 2.0e-04 0.03 0.02 0.01 0.02 1.3e-03 5.4e-03 4.8e-02 1.0e-02
5 Brain intron excision ratio chr7_122080857_122081004 0.06 0.05 1.5e-04 0.03 0.02 0.01 0.02 5.8e-04 3.8e-03 2.9e-02 4.7e-03
6 NAcc intron excision ratio chr7_122080927_122081004 0.03 0.02 1.6e-04 0.03 0.03 0.02 0.03 2.4e-05 7.0e-05 1.4e-04 4.0e-05
7 Liver alternative TSS NM_001035000.2 0.03 0.02 4.2e-04 0.03 0.03 0.03 0.03 3.1e-04 2.7e-04 4.7e-04 3.3e-04
8 BLA isoform ratio NM_001035000.2 0.08 0.06 3.3e-04 0.02 0.05 0.04 0.03 2.0e-02 1.6e-03 4.9e-03 6.3e-03
9 Liver alternative TSS XM_039079632.2 0.02 0.02 9.0e-04 0.02 0.02 0.01 0.02 9.7e-04 8.8e-04 2.3e-02 2.5e-03
10 IC alternative polyA XM_039079633.2 0.12 0.09 4.1e-03 0.01 0.01 0.04 0.01 9.8e-02 9.4e-02 1.1e-02 1.3e-01
11 Brain gene expression Hdac10 0.09 0.06 1.5e-05 0.06 0.05 0.05 0.06 1.4e-06 8.3e-06 1.2e-05 3.1e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density1.32.23.5-1.91.5-1.7-1.71.6-1.6-1.41.51.40.8-0.9
Area under the delay curve0.91.12.50.10.9-0.9-0.90.9-0.9-1.11.21.21.0-1.6
BMI with tail3.913.421.34.6-3.93.93.9-3.93.83.7-3.4-3.6-3.41.0
BMI without tail2.37.08.12.3-2.72.82.8-2.82.72.8-2.7-2.7-2.81.8
Body weight1.67.012.93.6-2.92.62.6-2.62.62.7-2.7-2.6-2.60.8
Weight adjusted by age2.13.26.62.6-1.91.91.9-1.91.81.6-1.6-1.5-1.6-0.2
Bone surface1.42.53.4-1.01.6-1.7-1.81.7-1.5-1.61.71.61.2-1.8
Bone volume1.62.83.5-1.31.7-1.8-1.81.7-1.7-1.71.91.71.4-1.6
Breakpoint value in progressive ratio session0.10.10.80.9-0.40.10.1-0.10.10.2-0.1-0.1-0.3-0.6
Number of licking bursts0.00.10.2-0.40.1-0.4-0.30.4-0.1-0.00.0-0.00.00.2
Context. condit. distance diff. score2.12.63.31.0-1.61.71.8-1.81.51.7-1.7-1.7-1.61.4
Locomotion velocity, session 10.10.20.50.7-0.40.20.2-0.20.40.4-0.3-0.4-0.7-0.1
Locomotion distance, session 12.53.23.9-1.21.9-2.0-1.91.9-1.9-1.81.81.81.9-1.4
Locomotion velocity, session 20.50.61.00.8-0.90.60.8-0.80.80.9-0.6-0.9-1.00.1
Locomotion distance, session 21.11.62.0-0.61.4-1.3-1.41.4-1.3-1.31.21.31.4-0.9
Locomotion velocity, session 30.60.73.5-1.0-0.40.20.2-0.20.30.7-0.9-0.8-1.01.9
Locomotion distance, session 30.10.10.8-0.90.1-0.1-0.20.2-0.2-0.10.20.10.10.5
Stereotopy head waving bouts, day 32.02.33.2-1.41.6-1.4-1.41.3-1.5-1.61.81.61.6-1.4
Stereotopy head waving duration, day 30.60.71.4-1.21.0-0.8-0.70.7-0.8-0.90.90.90.7-0.4
Locomotion velocity, session 71.51.72.5-0.0-1.41.51.5-1.51.31.2-1.0-1.3-1.01.6
Locomotion distance, session 70.40.50.70.4-0.80.70.7-0.70.80.7-0.7-0.7-0.60.9
Stereotopy head waving bouts, day 71.21.42.0-1.41.4-1.4-1.31.3-1.3-1.11.01.10.7-0.5
Stereotopy head waving duration, day 71.01.33.8-1.91.3-1.2-1.11.2-1.2-0.90.90.90.70.1
Locomotion velocity, session 81.41.73.30.2-1.31.31.3-1.31.31.4-1.2-1.4-1.81.3
Locomotion distance, session 80.40.61.41.2-0.70.90.8-0.80.70.8-0.9-0.8-0.60.3
Degree of sensitization distance1.41.43.31.8-1.21.11.2-1.31.31.1-1.1-1.0-1.0-0.1
Degree of sensitization stereotypy0.20.30.8-0.90.6-0.6-0.60.6-0.5-0.20.00.2-0.10.5
Conditioned locomotion0.50.60.80.7-0.90.60.6-0.60.90.9-0.8-0.9-0.60.7
Cocaine response after cond. corrected1.21.42.00.8-1.21.21.4-1.21.21.3-1.2-1.3-1.40.8
Cocaine response after cond. not corrected2.83.34.61.3-1.81.91.9-1.81.81.9-1.9-1.9-2.11.3
Cocaine response before conditioning1.01.21.51.0-1.11.21.1-1.21.11.1-1.0-1.1-1.10.6
Saline control response0.40.62.11.5-0.70.70.7-0.70.80.6-0.4-0.5-0.6-0.8
Bone: connectivity density1.11.74.6-2.11.2-1.5-1.61.6-1.3-1.11.21.00.5-0.4
Bone: cortical apparent density2.23.04.1-2.01.8-1.8-1.81.7-1.9-1.81.61.71.7-0.6
Bone: cortical area0.50.83.92.0-0.80.90.8-0.90.80.4-0.1-0.40.2-1.0
Bone: cortical porosity0.20.21.21.1-0.40.20.0-0.20.10.2-0.1-0.2-0.1-0.8
Bone: cortical porosity0.50.52.61.6-0.60.50.3-0.40.40.5-0.5-0.4-0.5-0.8
Bone: cortical thickness0.10.20.90.9-0.20.50.3-0.40.2-0.10.20.10.6-0.5
Bone: cortical thickness1.21.43.00.9-1.21.71.7-1.71.20.9-0.7-0.9-0.21.0
Bone: cortical tissue density1.92.63.8-1.91.7-1.7-1.81.7-1.8-1.61.51.61.6-0.5
Condit. Reinf. active minus inactive responses1.21.42.21.2-1.41.41.4-1.41.51.1-0.6-1.1-0.9-0.1
Condit. Reinf. active-inactive response ratio0.10.10.3-0.0-0.40.50.4-0.50.50.4-0.1-0.4-0.30.0
Condit. Reinf. active responses2.02.53.41.8-1.81.71.8-1.81.91.6-1.1-1.5-1.30.1
Condit. Reinf. inactive responses1.41.73.31.8-1.41.31.4-1.31.41.3-1.1-1.2-1.20.2
Incentive salience index mean1.92.33.71.9-1.81.71.7-1.81.81.4-0.9-1.4-1.1-0.3
Condit. Reinf. lever presses1.42.03.92.0-1.61.51.6-1.61.71.4-1.0-1.3-1.0-0.2
Condit. Reinf. active minus inactive responses0.40.62.70.70.2-0.2-0.20.2-0.3-0.71.00.70.9-1.7
Condit. Reinf. active-inactive response ratio0.10.10.40.3-0.10.10.1-0.10.0-0.30.50.30.4-0.6
Condit. Reinf. active responses0.40.52.31.4-0.50.50.5-0.50.5-0.10.40.10.4-1.5
Condit. Reinf. inactive responses0.40.51.91.4-0.70.70.7-0.70.70.5-0.4-0.5-0.1-0.6
Condit. Reinf. lever presses0.81.14.12.0-1.21.01.0-1.01.20.8-0.5-0.8-0.4-0.7
Condit. Reinf. lever reinforcers received0.40.52.71.3-0.30.30.3-0.30.3-0.20.60.30.5-1.7
Conditioned reinforcement - actives0.30.61.61.2-0.80.70.7-0.70.90.6-0.6-0.6-0.7-0.3
Conditioned reinforcement - inactives0.20.30.70.5-0.60.50.5-0.50.50.5-0.6-0.5-0.80.4
Conditioned locomotion2.43.24.72.2-1.91.91.9-1.92.01.8-1.8-1.7-1.60.6
Patch foraging indifference point 0 sec0.30.61.10.7-0.81.01.0-1.10.90.7-0.6-0.7-0.60.2
Patch foraging indifference point AUC1.21.85.70.61.0-1.2-1.21.2-1.1-1.21.31.31.2-2.4
Delay disc. indifference point, 0s delay0.60.73.71.9-0.60.50.5-0.50.50.30.0-0.20.0-1.5
Delay disc. indifference point, 16s delay0.30.31.00.30.4-0.6-0.60.6-0.5-0.50.60.60.3-1.0
Delay disc. indifference point, 2s delay3.94.39.8-0.11.8-1.8-1.81.8-1.8-2.22.52.32.3-3.1
Delay disc. indifference point, 24s delay0.50.50.90.7-0.90.80.8-0.80.90.7-0.6-0.7-0.60.2
Delay disc. indifference point, 4s delay1.41.42.10.21.3-1.3-1.31.3-1.3-1.21.11.31.0-1.5
Delay disc. indifference point, 8s delay0.91.01.4-0.61.1-1.0-1.01.0-1.0-1.21.11.21.0-0.9
Indifference point function ln k2.23.84.61.5-2.02.12.1-2.12.02.0-2.1-2.0-1.61.7
Indifference point function log k2.23.84.61.5-2.02.12.1-2.12.02.0-2.1-2.0-1.61.7
Patch foraging total patch changes 0 sec0.20.30.60.3-0.50.70.7-0.80.60.5-0.4-0.4-0.50.2
Patch foraging total patch changes 12 sec0.20.31.50.80.00.10.0-0.10.0-0.30.50.40.5-1.2
Patch foraging total patch changes 18 sec1.42.13.9-0.91.3-1.3-1.31.2-1.3-1.61.81.61.4-2.0
Patch foraging total patch changes 24 sec0.30.41.3-0.80.5-0.3-0.30.3-0.3-0.71.00.70.7-1.2
Patch foraging total patch changes 6 sec0.20.31.70.50.6-0.4-0.40.4-0.4-0.50.50.60.3-1.3
Patch foraging time to switch 0 sec0.10.30.9-1.00.6-0.5-0.40.5-0.5-0.50.50.40.40.1
Patch foraging water rate 0 sec0.61.21.71.3-1.11.21.1-1.21.01.1-1.3-1.1-0.80.7
Patch foraging water rate 12 sec1.53.24.21.9-1.82.02.0-2.01.91.7-1.8-1.7-1.60.7
Patch foraging water rate 18 sec3.65.66.81.8-2.32.52.5-2.52.42.4-2.6-2.4-2.42.0
Patch foraging water rate 24 sec1.11.62.60.6-1.01.31.2-1.31.11.3-1.6-1.3-1.51.3
Patch foraging water rate 6 sec0.60.91.41.0-0.90.90.9-0.90.91.0-1.2-1.0-0.80.7
Seeking ratio, delayed vs. immediate footshock0.50.61.0-1.00.8-0.9-0.90.9-0.9-0.70.70.70.60.3
Distance traveled before self-admin1.11.42.4-0.51.5-1.2-1.21.2-1.2-1.31.21.31.5-0.4
Distance traveled after self-admin0.10.10.9-0.40.1-0.3-0.30.3-0.20.00.0-0.1-0.10.9
Extensor digitorum longus weight0.41.72.11.1-1.31.31.4-1.41.41.4-1.3-1.4-1.31.0
Bone: elastic displacement0.60.61.2-1.11.0-0.7-1.10.8-1.1-0.70.50.70.1-0.5
Bone: elastic work0.10.20.40.6-0.30.50.2-0.40.30.3-0.4-0.3-0.6-0.2
Bone: endosteal estimation0.20.31.81.3-0.50.40.4-0.40.60.4-0.2-0.3-0.3-0.7
Bone: endosteal perimeter0.61.36.82.6-0.60.40.5-0.40.70.20.4-0.10.2-2.4
Epididymis fat weight1.65.59.73.1-2.72.72.6-2.62.72.2-1.6-2.2-1.8-0.2
Delta time in closed arm before/after self-admin0.10.10.20.50.10.20.2-0.20.2-0.20.10.20.2-0.3
Delta time in open arm before/after self-admin0.00.00.10.00.0-0.2-0.20.2-0.1-0.00.0-0.00.3-0.1
Diff in mean of infusions in LGA sessions0.91.12.81.7-1.11.11.1-1.11.10.8-0.6-0.8-0.7-0.8
Delay discount exponential model param0.80.91.7-0.0-0.90.90.9-0.90.91.0-1.1-1.1-0.91.3
Extinction: sum of active levers before priming0.40.40.70.30.5-0.7-0.70.7-0.7-0.60.60.70.3-0.8
Active lever presses in extinction session 62.22.24.01.5-1.61.41.4-1.41.51.5-1.5-1.5-2.00.8
Bone: final force0.10.20.80.7-0.0-0.0-0.0-0.0-0.0-0.30.40.30.9-0.6
Bone: final moment0.10.20.90.40.3-0.2-0.30.1-0.3-0.50.50.50.9-0.6
Food consumed during 24 hour testing period2.23.13.61.9-1.81.91.9-1.91.91.8-1.7-1.8-1.61.1
Glucose0.20.31.10.20.6-0.4-0.40.4-0.6-0.60.60.70.5-1.1
Heart weight0.50.81.30.2-0.81.11.0-1.10.80.9-0.9-0.9-0.91.1
Delay discount hyperbolic model param1.21.42.40.1-1.11.11.1-1.11.11.3-1.4-1.3-1.11.5
Intermittent access intake day 1-15 change0.51.01.51.2-0.91.11.1-1.11.10.9-0.9-0.9-1.10.2
Intermittent access intake escalation0.51.01.71.3-1.01.11.1-1.11.11.0-1.0-0.9-1.10.1
Intermittent access intake escalation 21.41.63.92.0-1.31.31.3-1.31.31.1-1.0-1.0-1.3-0.4
Intermitt. access day 1 inactive lever presses0.20.61.81.4-0.80.70.7-0.70.70.7-0.6-0.6-0.7-0.4
Intermitt. access day 15 inactive lever presses2.04.05.61.2-2.02.02.0-2.02.02.2-2.4-2.1-2.21.9
Intermitt. access escalation Index0.20.21.0-1.00.5-0.5-0.50.5-0.3-0.40.40.30.50.3
Intermittent access day 1 total infusions0.00.10.3-0.1-0.20.20.1-0.20.10.2-0.3-0.3-0.30.5
Intermittent access day 15 total infusions0.20.30.50.6-0.50.60.4-0.60.60.5-0.6-0.5-0.70.3
Intermittent access terminal intake (last 3 days)1.11.42.81.7-1.21.31.2-1.31.21.1-1.2-1.0-1.30.1
Intermittent access total infusions0.20.20.40.7-0.50.40.3-0.40.50.4-0.5-0.4-0.50.1
Intermittent access day 1 locomotion0.00.00.00.20.0-0.0-0.10.00.0-0.10.10.10.2-0.2
Intermittent access day 15 total locomotion0.50.92.21.5-1.01.00.9-1.01.00.9-0.9-0.8-0.9-0.1
Intermittent access total locomotion0.70.81.01.0-0.91.00.9-1.01.00.9-1.0-0.9-0.80.4
Intermittent access standard deviation0.40.71.30.4-0.70.90.8-0.90.70.8-1.0-0.9-1.11.0
Left kidney weight4.219.828.35.3-4.64.54.5-4.54.64.6-4.5-4.4-4.71.6
Right kidney weight6.730.741.16.4-5.85.65.6-5.55.75.8-5.7-5.6-6.02.3
Cocaine induced anxiety0.91.32.01.1-1.21.01.1-1.01.01.2-1.4-1.2-1.11.1
Post-drug Anxiety1.61.72.61.1-1.31.11.2-1.11.11.4-1.6-1.4-1.31.5
Baseline Anxiety0.30.40.9-0.90.7-0.5-0.50.5-0.7-0.60.60.60.5-0.1
Tail length0.41.62.7-1.61.4-1.6-1.41.5-1.4-1.21.11.10.5-0.2
Length with tail0.00.20.30.50.2-0.6-0.50.5-0.4-0.30.10.30.1-0.5
Length without tail0.20.74.92.2-0.60.30.3-0.30.50.4-0.5-0.3-0.3-1.1
Times rat made contact with spout1.72.05.50.2-1.11.21.1-1.21.21.4-1.8-1.4-1.52.4
Lifetime Intake0.30.30.50.7-0.60.50.4-0.50.60.5-0.6-0.5-0.70.3
Liver weight, left0.20.42.81.7-0.30.30.4-0.30.30.2-0.2-0.1-0.1-1.0
Liver weight, right0.20.30.70.60.5-0.4-0.40.4-0.5-0.60.40.60.4-0.9
Locomotor activity0.20.31.91.4-0.20.40.3-0.40.30.20.0-0.0-0.1-1.1
Locomotor testing distance0.51.01.6-0.71.2-0.9-1.10.9-1.1-1.11.01.10.9-0.6
Locomotor testing rearing0.81.77.51.11.0-0.8-0.80.8-0.9-1.21.41.31.2-2.7
Locomotion in novel chamber2.12.77.10.2-1.41.41.4-1.41.41.7-1.8-1.7-2.02.7
Locomotion in novel chamber post-restriction0.10.20.4-0.60.2-0.3-0.30.3-0.4-0.40.70.40.6-0.4
Fecal boli incidents, locomotor time 10.30.50.9-0.90.7-0.7-0.70.7-0.7-0.70.70.70.7-0.2
Change in fecal boli incidents, locomotor task0.50.40.60.8-0.70.70.7-0.70.70.6-0.7-0.6-0.70.2
Time >=10cm from walls, locomotor time 10.20.30.90.9-0.50.40.4-0.40.40.5-0.4-0.4-0.5-0.3
Bouts of movement, locomotor time 10.80.91.5-0.3-0.81.11.0-1.11.00.8-0.7-0.8-1.21.1
Total resting periods, locomotor time 10.40.41.0-0.8-0.40.60.6-0.60.60.4-0.3-0.4-1.00.9
Rest time, locomotor task time 10.30.42.3-1.5-0.10.10.1-0.10.10.2-0.2-0.3-0.61.3
Distance moved, locomotor task time 10.20.31.91.4-0.30.40.4-0.40.40.2-0.1-0.20.4-0.8
Vertical activity count, locomotor time 10.41.04.22.1-1.01.01.0-1.01.00.8-0.5-0.7-0.0-0.9
Time >=10cm from walls, locomotor time 21.21.73.21.8-1.61.41.4-1.41.41.3-1.2-1.3-0.9-0.2
Bouts of movement, locomotor time 20.10.20.4-0.30.5-0.6-0.60.6-0.6-0.50.50.50.3-0.0
Total resting periods, locomotor time 20.20.30.4-0.40.6-0.6-0.60.6-0.6-0.60.60.60.4-0.1
Rest time, locomotor task time 20.60.72.9-1.70.9-0.8-0.80.8-0.8-0.70.60.60.30.7
Distance moved, locomotor task time 21.41.74.22.0-1.51.41.4-1.41.41.2-1.0-1.1-0.5-0.5
Vertical activity count, locomotor time 21.42.04.22.0-1.71.61.6-1.61.61.3-1.0-1.2-0.4-0.6
Light reinforcement 10.20.51.91.4-0.60.70.7-0.70.60.6-0.4-0.5-0.7-0.8
Light reinforcement 21.82.710.03.2-1.71.51.5-1.41.61.4-1.3-1.3-1.4-0.8
Bone: marrow area0.10.21.31.2-0.30.20.3-0.20.40.2-0.1-0.2-0.2-0.8
Bone: maximum diameter1.01.95.72.4-1.61.51.4-1.41.51.2-0.8-1.2-0.7-0.4
Bone: maximum force0.00.10.50.7-0.10.00.1-0.10.1-0.10.10.10.4-0.4
Bone: maximum moment0.00.10.20.30.2-0.2-0.20.1-0.2-0.30.20.30.4-0.4
Mean time between licks in bursts1.12.85.5-2.31.7-1.9-1.81.9-1.7-1.61.41.51.40.0
Mean num. licks in bursts0.20.40.80.3-0.40.70.6-0.70.50.5-0.8-0.5-0.50.9
Cd content in liver0.50.61.1-0.60.8-0.8-0.70.7-0.8-0.90.90.90.5-1.1
Co content in liver0.10.10.70.5-0.20.20.0-0.10.10.3-0.2-0.2-0.5-0.8
Cu content in liver0.40.52.7-1.40.2-0.2-0.20.3-0.1-0.1-0.0-0.00.31.6
Fe content in liver0.20.31.00.20.4-0.4-0.40.4-0.3-0.50.60.60.7-1.0
K content in liver0.20.10.3-0.60.3-0.5-0.50.5-0.4-0.20.40.20.1-0.2
Mg content in liver1.21.21.6-0.81.2-1.2-1.21.2-1.2-1.11.21.10.9-1.1
Mn content in liver0.10.10.2-0.10.2-0.4-0.40.5-0.1-0.10.30.1-0.1-0.5
Na content in liver4.75.06.9-1.72.0-2.2-2.22.2-2.1-2.32.62.32.6-2.3
Rb content in liver0.10.10.80.30.2-0.2-0.30.3-0.1-0.30.40.30.3-0.9
Se content in liver0.30.41.5-0.1-0.50.40.4-0.40.40.7-0.7-0.7-1.20.8
Sr content in liver1.10.92.2-1.51.0-1.0-0.91.0-1.0-0.90.80.81.10.3
Zn content in liver0.40.50.9-1.00.8-0.8-0.70.8-0.9-0.50.20.50.20.6
Bone: minimum diameter0.40.72.71.6-0.80.90.8-0.80.90.4-0.1-0.40.0-0.8
Time in familiar zone, hab. session 10.40.41.5-0.1-0.40.30.3-0.40.50.7-0.9-0.7-0.91.2
Time in novel zone, hab. session 10.90.91.6-0.60.9-0.7-0.70.7-0.9-1.01.21.01.0-1.3
Total zone transitions, hab. session 12.73.84.8-1.12.1-2.2-2.22.2-2.0-2.11.82.12.0-1.3
Total locomotion distance, hab. session 10.50.71.20.70.9-0.9-0.90.9-0.8-0.70.50.90.6-1.1
Locomotion velocity, hab. session 10.60.91.70.81.0-1.0-1.01.0-0.9-0.90.71.00.8-1.3
Time in familiar zone, hab. session 22.12.22.80.5-1.51.51.5-1.61.51.6-1.5-1.6-1.41.7
Time in novel zone, hab. session 22.32.32.9-1.51.7-1.5-1.61.6-1.6-1.61.51.61.1-1.2
Total zone transitions, hab. session 20.10.10.30.5-0.20.30.2-0.20.30.3-0.5-0.3-0.10.4
Total locomotion distance, hab. session 20.60.82.21.5-0.80.80.8-0.70.80.9-1.1-0.8-0.80.2
Locomotion velocity, hab. session 20.50.72.61.6-0.70.70.7-0.70.70.8-1.0-0.7-0.70.0
Novel to familiar place preference ratio0.30.31.9-1.40.3-0.4-0.50.5-0.3-0.10.20.0-0.10.9
Novelty place preference0.30.31.6-1.30.2-0.3-0.30.3-0.10.1-0.0-0.2-0.31.0
Time in novel zone, NPP test0.40.42.2-1.50.2-0.3-0.40.4-0.20.1-0.1-0.2-0.41.2
Total zone transitions, NPP test0.60.91.4-0.51.1-1.1-1.21.1-1.1-1.00.71.00.8-0.4
Total locomotion distance, NPP test0.10.20.60.70.4-0.4-0.40.4-0.3-0.30.20.40.2-0.8
Locomotion velocity, NPP test0.10.20.80.90.2-0.3-0.30.3-0.2-0.20.00.30.1-0.7
Intraocular pressure0.20.31.90.6-0.10.30.3-0.3-0.1-0.30.70.30.7-1.4
Delta distance traveled before/after self-admin3.73.95.20.6-2.21.91.9-1.91.92.2-2.1-2.2-2.32.0
Delta ambulatory time before/after self-admin2.12.53.30.3-1.81.51.5-1.51.51.7-1.7-1.8-1.81.7
Parametrial fat weight0.30.73.51.9-1.00.80.7-0.80.80.7-0.6-0.6-0.2-0.1
Pavlov. Cond. lever latency1.21.53.0-1.71.5-1.4-1.41.4-1.4-1.20.91.10.70.1
Pavlov. Cond. magazine entry latency0.10.10.3-0.50.10.10.0-0.1-0.0-0.30.60.20.5-0.3
Pavlov. Cond. change in total contacts0.20.20.90.6-0.30.40.3-0.40.3-0.10.60.00.6-0.9
Pavlov. Cond. index score0.10.10.30.4-0.50.60.5-0.50.50.20.1-0.20.2-0.3
Pavlov. Cond. latency score0.30.30.60.7-0.70.80.7-0.70.70.4-0.1-0.40.1-0.2
Pavlov. Cond. lever contacts1.11.32.01.4-1.41.41.3-1.31.41.1-0.7-1.1-0.60.0
Pavlov. Cond. magazine entry number0.10.20.60.3-0.2-0.10.10.00.20.5-0.7-0.4-0.60.5
Pavlov. Cond. intertrial magazine entries0.91.12.81.7-1.21.01.1-1.11.21.0-0.8-1.0-0.9-0.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.20.3-0.30.40.3-0.30.3-0.00.3-0.00.4-0.4
Pavlov. Cond. response bias0.30.30.70.6-0.70.80.7-0.80.70.4-0.2-0.4-0.3-0.1
Pavlov. Cond. lever latency1.62.12.9-1.71.6-1.5-1.51.6-1.6-1.51.31.41.4-0.6
Pavlov. Cond. magazine entry latency0.91.02.31.5-1.21.11.1-1.11.10.9-0.8-0.9-0.70.2
Pavlov. Cond. change in total contacts0.20.31.81.4-0.40.40.3-0.40.40.00.2-0.00.3-0.9
Pavlov. Cond. index score1.01.33.61.9-1.31.11.1-1.21.21.0-0.9-1.0-0.90.1
Pavlov. Cond. latency score1.62.14.32.1-1.61.51.5-1.51.61.4-1.3-1.4-1.20.4
Pavlov. Cond. lever contacts1.62.23.11.8-1.61.51.5-1.61.71.5-1.3-1.5-1.40.6
Pavlov. Cond. magazine entry number1.21.53.5-1.91.3-1.3-1.31.3-1.3-1.11.01.10.9-0.2
Pavlov. Cond. intertrial magazine entries0.10.21.0-1.00.4-0.3-0.40.4-0.4-0.0-0.30.0-0.50.5
Pavlov. Cond. lever-magazine prob. diff.1.11.43.71.9-1.31.21.2-1.21.31.1-1.0-1.1-0.90.2
Pavlov. Cond. response bias0.60.81.91.4-1.00.90.9-0.91.00.8-0.6-0.8-0.80.1
Time in closed arm before self-admin1.72.14.9-0.50.7-1.4-1.41.4-1.4-1.31.81.32.2-1.8
Time in closed arm after self-admin0.70.83.10.80.3-0.3-0.30.3-0.4-0.71.10.81.5-1.8
Time in open arm before self-admin0.20.20.8-0.40.00.00.0-0.00.00.1-0.4-0.1-0.80.9
Time in open arm after self-admin0.10.10.4-0.1-0.20.10.1-0.10.20.2-0.3-0.2-0.60.4
Bone: periosteal estimation0.40.84.32.1-0.80.80.7-0.80.90.5-0.1-0.40.0-1.1
Bone: periosteal perimeter0.81.47.22.7-1.11.11.1-1.01.10.6-0.2-0.6-0.1-1.5
Bone: post-yield work0.40.61.0-0.90.9-0.8-0.60.7-0.7-0.90.60.81.00.1
Progressive ratio test 1 active lever presses0.20.21.4-0.3-0.20.10.0-0.10.20.3-0.5-0.4-0.61.2
Progressive ratio test 1 breakpoint0.10.21.2-0.4-0.10.0-0.1-0.00.10.3-0.4-0.3-0.51.1
Progressive ratio test 1 inactive lever presses0.10.10.50.7-0.40.30.3-0.30.20.3-0.3-0.3-0.40.1
Progressive ratio test 2 active lever presses0.80.91.71.0-1.00.90.9-0.90.91.0-1.0-0.9-1.30.5
Progressive ratio test 2 breakpoint0.60.71.30.8-0.80.80.7-0.80.80.8-0.9-0.8-1.10.3
Progressive ratio test 2 inactive lever presses0.61.02.11.4-0.91.00.9-1.00.90.9-1.0-0.9-1.20.1
Incentive Sensitization - Responses0.71.02.31.5-1.11.01.0-1.01.10.9-0.8-0.9-1.0-0.4
Incentive Sensitization - Breakpoint0.70.92.01.4-1.01.01.0-1.01.00.9-0.8-0.8-0.9-0.4
Sum of active levers in priming session hrs 5-60.00.00.20.1-0.40.10.1-0.10.20.20.0-0.2-0.2-0.2
Progressive ratio0.30.40.80.2-0.60.50.5-0.50.60.7-0.6-0.7-0.80.9
Food seeking constrained by brief footshock2.53.05.52.3-1.81.71.7-1.71.81.8-1.9-1.7-1.80.3
Seeking ratio, punishment vs. effort0.20.21.41.00.00.10.1-0.10.1-0.10.10.20.5-1.2
Retroperitoneal fat weight2.18.816.14.0-3.33.23.1-3.13.32.9-2.5-2.8-2.60.2
Reaction time number correct0.50.91.3-0.91.0-1.1-1.11.1-1.0-0.90.80.91.0-0.4
Reaction time mean minus median0.00.10.50.7-0.30.30.3-0.30.30.2-0.1-0.2-0.2-0.1
Reaction time mean minus median AUC0.10.20.40.5-0.30.30.4-0.30.40.4-0.4-0.4-0.60.3
Reaction time num false alarms0.10.10.5-0.70.2-0.00.00.0-0.2-0.30.50.20.2-0.0
Reaction time num false alarms AUC0.10.10.5-0.7-0.10.20.3-0.30.10.00.1-0.1-0.20.6
Reaction time trials correct on left0.50.91.3-0.91.0-1.1-1.11.1-1.0-0.90.80.91.0-0.4
Reaction time trials on left0.50.91.3-0.91.0-1.0-1.11.1-1.0-0.90.80.90.9-0.4
Reaction time mean0.10.21.1-0.8-0.0-0.1-0.10.1-0.00.0-0.1-0.1-0.21.1
Reaction time mean AUC0.10.20.8-0.90.1-0.3-0.20.3-0.2-0.10.00.0-0.10.9
Median of all reaction times0.30.42.3-1.3-0.0-0.1-0.10.2-0.00.1-0.3-0.2-0.31.5
Reaction time omissions0.10.21.2-1.10.4-0.1-0.10.1-0.3-0.40.40.30.10.4
Reaction time false alarm rate0.20.20.5-0.3-0.40.60.7-0.60.40.3-0.1-0.3-0.50.5
Reaction time premature initiation rate1.92.76.12.5-1.81.82.0-1.91.81.4-1.0-1.3-0.9-0.9
Reaction time premature initiations0.50.92.61.6-1.01.01.0-1.00.90.7-0.4-0.6-0.2-0.9
Std. dev. reaction times0.20.30.40.5-0.50.60.6-0.60.50.5-0.5-0.5-0.50.6
Reaction time trials completed0.50.91.3-0.91.0-1.0-1.11.1-1.0-0.90.80.90.9-0.4
Reaction time trials AUC0.30.50.9-0.60.8-0.8-0.90.9-0.8-0.70.60.70.8-0.3
Run reversals in cocaine runway, females0.20.20.5-0.2-0.20.30.3-0.30.30.4-0.5-0.4-0.70.7
Run reversals in cocaine runway, males1.11.11.6-0.41.0-1.0-1.01.0-1.0-1.11.21.10.9-1.3
Latency to leave start box in cocaine runway2.02.33.31.4-1.61.51.5-1.51.41.7-1.8-1.6-1.41.3
Latency to leave start box in cocaine runway, F4.24.87.11.0-2.22.12.1-2.12.02.4-2.7-2.5-2.22.6
Latency to leave start box in cocaine runway, M0.40.41.61.20.2-0.2-0.20.2-0.2-0.40.50.50.6-1.3
Std. dev. time between licks in bursts0.50.73.61.9-0.60.50.6-0.50.70.6-0.7-0.5-0.6-0.8
Total sessions with >9 infusions0.40.50.80.5-0.70.60.5-0.60.60.7-0.8-0.7-0.80.9
Short access day 1 total inactive lever presses4.35.76.62.3-2.42.52.5-2.52.32.5-2.6-2.4-2.51.8
Short access day 10 total inactive lever presses3.07.411.83.4-2.92.93.0-2.93.12.7-2.5-2.6-2.30.3
Short access day 1 total infusions1.31.72.41.0-1.31.21.1-1.21.31.3-1.5-1.3-1.61.3
Short access day 10 total infusions0.91.21.61.0-1.21.11.0-1.11.11.2-1.2-1.1-1.30.9
Short access total infusions0.81.01.31.1-1.01.00.9-1.01.01.0-1.1-1.0-1.20.8
Short access day 1 locomotion1.11.42.00.7-1.21.11.1-1.11.11.3-1.4-1.3-1.31.2
Short access day 10 total locomotion0.71.31.81.1-1.21.31.3-1.31.31.2-1.2-1.1-1.00.6
Short access total locomotion0.60.80.91.0-0.91.00.9-1.01.00.9-0.9-0.9-0.80.6
One hour access (0.3 mA shock)0.70.82.91.7-0.90.80.8-0.80.90.8-0.8-0.7-0.8-0.3
Compulsive drug intake0.00.00.1-0.10.1-0.0-0.00.0-0.1-0.10.20.10.3-0.3
One hour access (shock baseline)0.30.51.71.3-0.70.60.6-0.60.70.6-0.6-0.5-0.8-0.3
Social response proportion0.20.31.10.10.4-0.3-0.30.3-0.2-0.60.70.51.0-0.6
Social responses0.20.21.00.30.3-0.2-0.20.2-0.2-0.40.70.41.0-0.7
Social time0.70.92.50.5-0.70.80.8-0.80.80.9-1.2-1.0-0.91.6
Soleus weight1.23.44.12.0-1.92.01.8-1.91.81.9-1.9-1.9-1.81.3
Bone: stiffness0.10.10.50.20.2-0.4-0.30.4-0.2-0.40.30.40.7-0.2
Tibialis anterior weight0.10.20.30.0-0.40.40.5-0.60.40.5-0.4-0.5-0.50.6
Time to tail flick, vehicle, before self-admin1.31.43.01.7-1.21.21.2-1.21.21.1-1.0-1.1-1.3-0.3
Time to tail flick, vehicle, after self-admin0.40.61.01.0-1.00.70.7-0.70.70.8-0.7-0.8-0.30.1
Time to tail flick, test, before self-admin0.40.50.80.7-0.90.80.8-0.80.80.7-0.5-0.7-0.00.4
Time to tail flick, test, after self-admin3.73.94.91.4-2.22.02.0-2.02.02.1-2.1-2.1-1.91.6
Delta time to tail flick, vehicle, before/after SA0.60.61.2-1.10.7-0.8-0.80.8-0.8-0.70.70.71.00.1
Delta time to tail flick, test, before/after SA0.30.30.90.2-0.40.40.4-0.40.40.6-0.8-0.6-1.00.5
Tibia length1.23.44.3-1.21.9-2.1-2.02.1-1.8-2.01.72.02.0-1.2
Ambulatory time before self-admin0.20.30.6-0.30.8-0.6-0.60.6-0.5-0.50.40.50.80.5
Ambulatory time after self-admin0.30.31.8-0.3-0.40.30.3-0.30.30.6-0.5-0.6-0.61.3
Bone: tissue strength1.41.42.7-1.61.4-1.4-1.51.4-1.5-1.00.51.00.50.2
Total heroin consumption0.10.10.30.5-0.20.20.2-0.20.20.1-0.0-0.1-0.4-0.6
Bone: trabecular number1.01.74.6-2.11.3-1.4-1.41.4-1.5-1.11.21.10.4-0.6
Bone: trabecular spacing2.12.85.32.3-1.71.71.8-1.81.81.6-1.7-1.6-1.10.8
Bone: trabecular thickness0.20.31.10.40.3-0.3-0.30.4-0.5-0.50.70.50.6-1.1
Bone: trabecular tissue density1.52.23.4-0.71.4-1.6-1.71.7-1.4-1.61.41.51.9-1.1
Water consumed over 24 hours0.20.20.50.7-0.40.30.2-0.30.40.4-0.7-0.4-0.60.4
Number of responses in last shaping day0.10.10.5-0.70.3-0.2-0.20.2-0.3-0.20.00.2-0.10.6