Hub : Genes

Hdac10

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Hdac10 0.08 0.06 2.3e-06 0.04 0.04 0.05 0.04 1.7e-05 1.0e-05 2.6e-06 1.1e-05
2 NAcc intron excision ratio chr7_122080857_122081004 0.03 0.02 2.6e-04 0.03 0.02 0.03 0.03 4.9e-05 1.5e-04 9.9e-05 6.3e-05
3 Adipose mRNA stability Hdac10 0.02 0.02 4.0e-03 0.02 0.01 0.01 0.02 2.0e-03 1.0e-02 3.4e-02 6.2e-03
4 Brain intron excision ratio chr7_122080927_122081004 0.06 0.04 2.0e-04 0.03 0.02 0.01 0.02 1.3e-03 5.4e-03 4.8e-02 8.2e-03
5 Brain intron excision ratio chr7_122080857_122081004 0.06 0.05 1.5e-04 0.03 0.02 0.01 0.02 5.8e-04 3.8e-03 2.9e-02 4.6e-03
6 NAcc intron excision ratio chr7_122080927_122081004 0.03 0.02 1.6e-04 0.03 0.03 0.02 0.03 2.4e-05 7.0e-05 1.4e-04 4.0e-05
7 BLA isoform ratio NM_001414972.1 0.05 0.03 6.2e-03 0.02 0.02 0.01 0.02 2.6e-02 1.8e-02 7.1e-02 2.3e-02
8 Liver alternative TSS NM_001035000.2 0.03 0.02 4.2e-04 0.03 0.03 0.03 0.03 3.1e-04 2.7e-04 4.7e-04 3.4e-04
9 BLA isoform ratio NM_001035000.2 0.08 0.06 3.3e-04 0.02 0.05 0.04 0.03 2.0e-02 1.6e-03 4.8e-03 6.4e-03
10 Liver alternative TSS XM_039079632.2 0.02 0.02 9.0e-04 0.02 0.02 0.01 0.02 9.7e-04 8.8e-04 2.2e-02 2.7e-03
11 IC alternative polyA XM_039079633.2 0.12 0.09 4.1e-03 0.01 0.01 0.04 0.01 9.8e-02 9.4e-02 1.1e-02 1.3e-01
12 Brain gene expression Hdac10 0.09 0.06 1.5e-05 0.06 0.05 0.05 0.06 1.4e-06 8.3e-06 1.2e-05 3.2e-06

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density1.22.23.51.9-1.51.71.7-1.61.6-1.5-1.41.51.4-0.80.9
Area under the delay curve0.71.12.5-0.1-0.90.90.9-0.90.9-1.1-1.11.21.2-1.01.6
BMI with tail3.913.521.3-4.63.9-3.9-3.93.9-3.83.83.7-3.4-3.63.4-1.0
BMI without tail1.37.18.1-2.32.7-2.8-2.82.8-2.72.82.8-2.7-2.72.8-1.8
Body weight1.67.112.9-3.62.9-2.6-2.62.6-2.62.82.7-2.7-2.62.6-0.8
Weight adjusted by age1.13.26.6-2.61.9-1.9-1.91.9-1.81.81.6-1.6-1.51.60.2
Bone surface1.32.53.41.0-1.61.71.8-1.71.5-1.6-1.61.71.6-1.21.8
Bone volume1.42.83.51.3-1.71.81.8-1.71.7-1.8-1.71.91.7-1.41.6
Breakpoint value in progressive ratio session0.10.10.8-0.90.4-0.1-0.10.1-0.10.20.2-0.1-0.10.30.6
Number of licking bursts0.00.10.20.4-0.10.40.3-0.40.1-0.0-0.00.0-0.0-0.0-0.2
Context. condit. distance diff. score2.12.63.3-1.01.6-1.7-1.81.8-1.51.71.7-1.7-1.71.6-1.4
Locomotion velocity, session 10.10.20.5-0.70.4-0.2-0.20.2-0.40.40.4-0.3-0.40.70.1
Locomotion distance, session 12.53.23.91.2-1.92.01.9-1.91.9-1.8-1.81.81.8-1.91.4
Locomotion velocity, session 20.50.61.0-0.80.9-0.6-0.80.8-0.80.80.9-0.6-0.91.0-0.1
Locomotion distance, session 21.11.52.00.6-1.41.31.4-1.41.3-1.2-1.31.21.3-1.40.9
Locomotion velocity, session 30.60.73.51.00.4-0.2-0.20.2-0.30.70.7-0.9-0.81.0-1.9
Locomotion distance, session 30.10.10.80.9-0.10.10.2-0.20.2-0.2-0.10.20.1-0.1-0.5
Stereotopy head waving bouts, day 32.02.33.21.4-1.61.41.4-1.31.5-1.7-1.61.81.6-1.61.4
Stereotopy head waving duration, day 30.60.71.41.2-1.00.80.7-0.70.8-0.9-0.90.90.9-0.70.4
Locomotion velocity, session 71.51.62.50.01.4-1.5-1.51.5-1.31.11.2-1.0-1.31.0-1.6
Locomotion distance, session 70.40.50.7-0.40.8-0.7-0.70.7-0.80.70.7-0.7-0.70.6-0.9
Stereotopy head waving bouts, day 71.21.42.01.4-1.41.41.3-1.31.3-1.1-1.11.01.1-0.70.5
Stereotopy head waving duration, day 71.01.23.81.9-1.31.21.1-1.21.2-1.0-0.90.90.9-0.7-0.1
Locomotion velocity, session 81.41.73.3-0.21.3-1.3-1.31.3-1.31.31.4-1.2-1.41.8-1.3
Locomotion distance, session 80.40.71.4-1.20.7-0.9-0.80.8-0.70.90.8-0.9-0.80.6-0.3
Degree of sensitization distance1.31.43.3-1.81.2-1.1-1.21.3-1.31.21.1-1.1-1.01.00.1
Degree of sensitization stereotypy0.20.20.80.9-0.60.60.6-0.60.5-0.2-0.20.00.20.1-0.5
Conditioned locomotion0.50.60.8-0.70.9-0.6-0.60.6-0.90.80.9-0.8-0.90.6-0.7
Cocaine response after cond. corrected1.01.42.0-0.81.2-1.2-1.41.2-1.21.31.3-1.2-1.31.4-0.8
Cocaine response after cond. not corrected2.33.34.6-1.31.8-1.9-1.91.8-1.81.91.9-1.9-1.92.1-1.3
Cocaine response before conditioning1.01.21.5-1.01.1-1.2-1.11.2-1.11.11.1-1.0-1.11.1-0.6
Saline control response0.40.62.1-1.50.7-0.7-0.70.7-0.80.60.6-0.4-0.50.60.8
Bone: connectivity density1.11.74.62.1-1.21.51.6-1.61.3-1.1-1.11.21.0-0.50.4
Bone: cortical apparent density1.93.04.12.0-1.81.81.8-1.71.9-1.8-1.81.61.7-1.70.6
Bone: cortical area0.50.73.9-2.00.8-0.9-0.80.9-0.80.40.4-0.1-0.4-0.21.0
Bone: cortical porosity0.20.21.2-1.10.4-0.2-0.00.2-0.10.30.2-0.1-0.20.10.8
Bone: cortical porosity0.40.52.6-1.60.6-0.5-0.30.4-0.40.70.5-0.5-0.40.50.8
Bone: cortical thickness0.10.20.9-0.90.2-0.5-0.30.4-0.2-0.1-0.10.20.1-0.60.5
Bone: cortical thickness1.11.43.0-0.91.2-1.7-1.71.7-1.20.80.9-0.7-0.90.2-1.0
Bone: cortical tissue density1.72.73.81.9-1.71.71.8-1.71.8-1.7-1.61.51.6-1.60.5
Condit. Reinf. active minus inactive responses1.21.32.2-1.21.4-1.4-1.41.4-1.51.01.1-0.6-1.10.90.1
Condit. Reinf. active-inactive response ratio0.10.10.30.00.4-0.5-0.40.5-0.50.20.4-0.1-0.40.3-0.0
Condit. Reinf. active responses1.92.43.4-1.81.8-1.7-1.81.8-1.91.41.6-1.1-1.51.3-0.1
Condit. Reinf. inactive responses1.31.73.3-1.81.4-1.3-1.41.3-1.41.31.3-1.1-1.21.2-0.2
Incentive salience index mean1.82.33.7-1.91.8-1.7-1.71.8-1.81.31.4-0.9-1.41.10.3
Condit. Reinf. lever presses1.32.03.9-2.01.6-1.5-1.61.6-1.71.31.4-1.0-1.31.00.2
Condit. Reinf. active minus inactive responses0.40.62.7-0.7-0.20.20.2-0.20.3-0.7-0.71.00.7-0.91.7
Condit. Reinf. active-inactive response ratio0.10.10.4-0.30.1-0.1-0.10.1-0.0-0.4-0.30.50.3-0.40.6
Condit. Reinf. active responses0.30.52.3-1.40.5-0.5-0.50.5-0.5-0.1-0.10.40.1-0.41.5
Condit. Reinf. inactive responses0.30.51.9-1.40.7-0.7-0.70.7-0.70.50.5-0.4-0.50.10.6
Condit. Reinf. lever presses0.81.14.1-2.01.2-1.0-1.01.0-1.20.80.8-0.5-0.80.40.7
Condit. Reinf. lever reinforcers received0.30.52.7-1.30.3-0.3-0.30.3-0.3-0.3-0.20.60.3-0.51.7
Conditioned reinforcement - actives0.10.61.6-1.20.8-0.7-0.70.7-0.90.70.6-0.6-0.60.70.3
Conditioned reinforcement - inactives0.10.30.7-0.50.6-0.5-0.50.5-0.50.60.5-0.6-0.50.8-0.4
Conditioned locomotion2.23.24.7-2.21.9-1.9-1.91.9-2.01.81.8-1.8-1.71.6-0.6
Patch foraging indifference point 0 sec0.20.61.1-0.70.8-1.0-1.01.1-0.90.70.7-0.6-0.70.6-0.2
Patch foraging indifference point AUC0.71.75.7-0.6-1.01.21.2-1.21.1-1.1-1.21.31.3-1.22.4
Delay disc. indifference point, 0s delay0.50.63.7-1.90.6-0.5-0.50.5-0.50.30.30.0-0.2-0.01.5
Delay disc. indifference point, 16s delay0.20.31.0-0.3-0.40.60.6-0.60.5-0.5-0.50.60.6-0.31.0
Delay disc. indifference point, 2s delay3.94.49.80.1-1.81.81.8-1.81.8-2.2-2.22.52.3-2.33.1
Delay disc. indifference point, 24s delay0.30.50.9-0.70.9-0.8-0.80.8-0.90.70.7-0.6-0.70.6-0.2
Delay disc. indifference point, 4s delay1.31.42.1-0.2-1.31.31.3-1.31.3-1.1-1.21.11.3-1.01.5
Delay disc. indifference point, 8s delay0.61.01.40.6-1.11.01.0-1.01.0-1.1-1.21.11.2-1.00.9
Indifference point function ln k1.33.84.6-1.52.0-2.1-2.12.1-2.02.02.0-2.1-2.01.6-1.7
Indifference point function log k1.33.84.6-1.52.0-2.1-2.12.1-2.02.02.0-2.1-2.01.6-1.7
Patch foraging total patch changes 0 sec0.10.30.6-0.30.5-0.7-0.70.8-0.60.50.5-0.4-0.40.5-0.2
Patch foraging total patch changes 12 sec0.20.21.5-0.8-0.0-0.1-0.00.1-0.0-0.3-0.30.50.4-0.51.2
Patch foraging total patch changes 18 sec0.92.23.90.9-1.31.31.3-1.21.3-1.6-1.61.81.6-1.42.0
Patch foraging total patch changes 24 sec0.10.51.30.8-0.50.30.3-0.30.3-0.8-0.71.00.7-0.71.2
Patch foraging total patch changes 6 sec0.20.31.7-0.5-0.60.40.4-0.40.4-0.4-0.50.50.6-0.31.3
Patch foraging time to switch 0 sec0.10.30.91.0-0.60.50.4-0.50.5-0.5-0.50.50.4-0.4-0.1
Patch foraging water rate 0 sec0.31.21.7-1.31.1-1.2-1.11.2-1.01.21.1-1.3-1.10.8-0.7
Patch foraging water rate 12 sec0.83.24.2-1.91.8-2.0-2.02.0-1.91.81.7-1.8-1.71.6-0.7
Patch foraging water rate 18 sec2.55.66.8-1.82.3-2.5-2.52.5-2.42.52.4-2.6-2.42.4-2.0
Patch foraging water rate 24 sec1.11.62.6-0.61.0-1.3-1.21.3-1.11.41.3-1.6-1.31.5-1.3
Patch foraging water rate 6 sec0.60.91.4-1.00.9-0.9-0.90.9-0.91.11.0-1.2-1.00.8-0.7
Seeking ratio, delayed vs. immediate footshock0.40.61.01.0-0.80.90.9-0.90.9-0.8-0.70.70.7-0.6-0.3
Distance traveled before self-admin0.71.42.40.5-1.51.21.2-1.21.2-1.3-1.31.21.3-1.50.4
Distance traveled after self-admin0.10.10.90.4-0.10.30.3-0.30.2-0.00.00.0-0.10.1-0.9
Extensor digitorum longus weight0.41.72.1-1.11.3-1.3-1.41.4-1.41.41.4-1.3-1.41.3-1.0
Bone: elastic displacement0.50.61.21.1-1.00.71.1-0.81.1-0.6-0.70.50.7-0.10.5
Bone: elastic work0.10.20.4-0.60.3-0.5-0.20.4-0.30.40.3-0.4-0.30.60.2
Bone: endosteal estimation0.10.31.8-1.30.5-0.4-0.40.4-0.60.40.4-0.2-0.30.30.7
Bone: endosteal perimeter0.51.26.8-2.60.6-0.4-0.50.4-0.70.20.20.4-0.1-0.22.4
Epididymis fat weight1.15.49.7-3.12.7-2.7-2.62.6-2.72.12.2-1.6-2.21.80.2
Delta time in closed arm before/after self-admin0.10.10.2-0.5-0.1-0.2-0.20.2-0.2-0.1-0.20.10.2-0.20.3
Delta time in open arm before/after self-admin0.00.00.1-0.0-0.00.20.2-0.20.1-0.0-0.00.0-0.0-0.30.1
Diff in mean of infusions in LGA sessions0.61.12.8-1.71.1-1.1-1.11.1-1.10.90.8-0.6-0.80.70.8
Delay discount exponential model param0.70.91.70.00.9-0.9-0.90.9-0.91.01.0-1.1-1.10.9-1.3
Extinction: sum of active levers before priming0.30.40.7-0.3-0.50.70.7-0.70.7-0.6-0.60.60.7-0.30.8
Active lever presses in extinction session 62.32.34.0-1.51.6-1.4-1.41.4-1.51.61.5-1.5-1.52.0-0.8
Bone: final force0.10.20.8-0.70.00.00.00.00.0-0.3-0.30.40.3-0.90.6
Bone: final moment0.10.20.9-0.4-0.30.20.3-0.10.3-0.5-0.50.50.5-0.90.6
Food consumed during 24 hour testing period1.53.13.6-1.91.8-1.9-1.91.9-1.91.81.8-1.7-1.81.6-1.1
Glucose0.20.31.1-0.2-0.60.40.4-0.40.6-0.5-0.60.60.7-0.51.1
Heart weight0.50.81.3-0.20.8-1.1-1.01.1-0.80.80.9-0.9-0.90.9-1.1
Delay discount hyperbolic model param1.11.42.4-0.11.1-1.1-1.11.1-1.11.31.3-1.4-1.31.1-1.5
Intermittent access intake day 1-15 change0.21.01.5-1.20.9-1.1-1.11.1-1.11.00.9-0.9-0.91.1-0.2
Intermittent access intake escalation0.21.11.7-1.31.0-1.1-1.11.1-1.11.01.0-1.0-0.91.1-0.1
Intermittent access intake escalation 20.91.63.9-2.01.3-1.3-1.31.3-1.31.21.1-1.0-1.01.30.4
Intermitt. access day 1 inactive lever presses0.00.61.8-1.40.8-0.7-0.70.7-0.70.70.7-0.6-0.60.70.4
Intermitt. access day 15 inactive lever presses0.84.15.6-1.22.0-2.0-2.02.0-2.02.22.2-2.4-2.12.2-1.9
Intermitt. access escalation Index0.10.21.01.0-0.50.50.5-0.50.3-0.5-0.40.40.3-0.5-0.3
Intermittent access day 1 total infusions0.00.10.30.10.2-0.2-0.10.2-0.10.20.2-0.3-0.30.3-0.5
Intermittent access day 15 total infusions0.10.30.5-0.60.5-0.6-0.40.6-0.60.60.5-0.6-0.50.7-0.3
Intermittent access terminal intake (last 3 days)0.81.52.8-1.71.2-1.3-1.21.3-1.21.21.1-1.2-1.01.3-0.1
Intermittent access total infusions0.20.20.4-0.70.5-0.4-0.30.4-0.50.50.4-0.5-0.40.5-0.1
Intermittent access day 1 locomotion0.00.00.0-0.2-0.00.00.1-0.0-0.0-0.1-0.10.10.1-0.20.2
Intermittent access day 15 total locomotion0.20.92.2-1.51.0-1.0-0.91.0-1.01.00.9-0.9-0.80.90.1
Intermittent access total locomotion0.70.81.0-1.00.9-1.0-0.91.0-1.01.00.9-1.0-0.90.8-0.4
Intermittent access standard deviation0.10.71.3-0.40.7-0.9-0.80.9-0.70.90.8-1.0-0.91.1-1.0
Left kidney weight2.520.028.3-5.34.6-4.5-4.54.5-4.64.84.6-4.5-4.44.7-1.6
Right kidney weight4.431.141.1-6.45.8-5.6-5.65.5-5.75.95.8-5.7-5.66.0-2.3
Cocaine induced anxiety0.51.32.0-1.11.2-1.0-1.11.0-1.01.31.2-1.4-1.21.1-1.1
Post-drug Anxiety1.51.82.6-1.11.3-1.1-1.21.1-1.11.51.4-1.6-1.41.3-1.5
Baseline Anxiety0.20.40.90.9-0.70.50.5-0.50.7-0.6-0.60.60.6-0.50.1
Tail length0.31.62.71.6-1.41.61.4-1.51.4-1.2-1.21.11.1-0.50.2
Length with tail0.00.10.3-0.5-0.20.60.5-0.50.4-0.2-0.30.10.3-0.10.5
Length without tail0.10.64.9-2.20.6-0.3-0.30.3-0.50.60.4-0.5-0.30.31.1
Times rat made contact with spout1.72.05.5-0.11.1-1.2-1.11.2-1.21.51.4-1.8-1.41.5-2.4
Lifetime Intake0.30.30.5-0.70.6-0.5-0.40.5-0.60.60.5-0.6-0.50.7-0.3
Liver weight, left0.20.42.8-1.70.3-0.3-0.40.3-0.30.30.2-0.2-0.10.11.0
Liver weight, right0.20.30.7-0.6-0.50.40.4-0.40.5-0.4-0.60.40.6-0.40.9
Locomotor activity0.20.31.9-1.40.2-0.4-0.30.4-0.30.20.20.0-0.00.11.1
Locomotor testing distance0.41.01.60.7-1.20.91.1-0.91.1-1.1-1.11.01.1-0.90.6
Locomotor testing rearing0.51.77.5-1.1-1.00.80.8-0.80.9-1.1-1.21.41.3-1.22.7
Locomotion in novel chamber2.02.77.1-0.21.4-1.4-1.41.4-1.41.61.7-1.8-1.72.0-2.7
Locomotion in novel chamber post-restriction0.10.20.40.6-0.20.30.3-0.30.4-0.5-0.40.70.4-0.60.4
Fecal boli incidents, locomotor time 10.20.50.90.9-0.70.70.7-0.70.7-0.8-0.70.70.7-0.70.2
Change in fecal boli incidents, locomotor task0.40.40.6-0.80.7-0.7-0.70.7-0.70.70.6-0.7-0.60.7-0.2
Time >=10cm from walls, locomotor time 10.20.30.9-0.90.5-0.4-0.40.4-0.40.50.5-0.4-0.40.50.3
Bouts of movement, locomotor time 10.70.81.50.30.8-1.1-1.01.1-1.00.70.8-0.7-0.81.2-1.1
Total resting periods, locomotor time 10.30.41.00.80.4-0.6-0.60.6-0.60.30.4-0.3-0.41.0-0.9
Rest time, locomotor task time 10.20.42.31.50.1-0.1-0.10.1-0.10.10.2-0.2-0.30.6-1.3
Distance moved, locomotor task time 10.10.31.9-1.40.3-0.4-0.40.4-0.40.30.2-0.1-0.2-0.40.8
Vertical activity count, locomotor time 10.11.04.2-2.11.0-1.0-1.01.0-1.00.80.8-0.5-0.70.00.9
Time >=10cm from walls, locomotor time 20.61.83.2-1.81.6-1.4-1.41.4-1.41.41.3-1.2-1.30.90.2
Bouts of movement, locomotor time 20.10.20.40.3-0.50.60.6-0.60.6-0.5-0.50.50.5-0.30.0
Total resting periods, locomotor time 20.10.30.40.4-0.60.60.6-0.60.6-0.6-0.60.60.6-0.40.1
Rest time, locomotor task time 20.40.72.91.7-0.90.80.8-0.80.8-0.8-0.70.60.6-0.3-0.7
Distance moved, locomotor task time 21.21.64.2-2.01.5-1.4-1.41.4-1.41.21.2-1.0-1.10.50.5
Vertical activity count, locomotor time 20.82.04.2-2.01.7-1.6-1.61.6-1.61.31.3-1.0-1.20.40.6
Light reinforcement 10.10.51.9-1.40.6-0.7-0.70.7-0.60.60.6-0.4-0.50.70.8
Light reinforcement 21.22.710.0-3.21.7-1.5-1.51.4-1.61.51.4-1.3-1.31.40.8
Bone: marrow area0.10.21.3-1.20.3-0.2-0.30.2-0.40.30.2-0.1-0.20.20.8
Bone: maximum diameter0.91.85.7-2.41.6-1.5-1.41.4-1.51.11.2-0.8-1.20.70.4
Bone: maximum force0.00.10.5-0.70.1-0.0-0.10.1-0.1-0.0-0.10.10.1-0.40.4
Bone: maximum moment0.00.10.2-0.3-0.20.20.2-0.10.2-0.2-0.30.20.3-0.40.4
Mean time between licks in bursts0.52.85.52.3-1.71.91.8-1.91.7-1.6-1.61.41.5-1.4-0.0
Mean num. licks in bursts0.10.40.8-0.30.4-0.7-0.60.7-0.50.60.5-0.8-0.50.5-0.9
Cd content in liver0.60.61.10.6-0.80.80.7-0.70.8-0.8-0.90.90.9-0.51.1
Co content in liver0.10.10.7-0.50.2-0.2-0.00.1-0.10.30.3-0.2-0.20.50.8
Cu content in liver0.40.42.71.4-0.20.20.2-0.30.1-0.2-0.1-0.0-0.0-0.3-1.6
Fe content in liver0.20.31.0-0.2-0.40.40.4-0.40.3-0.5-0.50.60.6-0.71.0
K content in liver0.10.10.30.6-0.30.50.5-0.50.4-0.3-0.20.40.2-0.10.2
Mg content in liver1.11.21.60.8-1.21.21.2-1.21.2-1.1-1.11.21.1-0.91.1
Mn content in liver0.10.10.20.1-0.20.40.4-0.50.1-0.2-0.10.30.10.10.5
Na content in liver4.55.16.91.7-2.02.22.2-2.22.1-2.5-2.32.62.3-2.62.3
Rb content in liver0.10.10.8-0.3-0.20.20.3-0.30.1-0.3-0.30.40.3-0.30.9
Se content in liver0.30.41.50.10.5-0.4-0.40.4-0.40.60.7-0.7-0.71.2-0.8
Sr content in liver1.10.92.21.5-1.01.00.9-1.01.0-1.0-0.90.80.8-1.1-0.3
Zn content in liver0.40.40.91.0-0.80.80.7-0.80.9-0.5-0.50.20.5-0.2-0.6
Bone: minimum diameter0.30.62.7-1.60.8-0.9-0.80.8-0.90.40.4-0.1-0.4-0.00.8
Time in familiar zone, hab. session 10.40.41.50.10.4-0.3-0.30.4-0.50.70.7-0.9-0.70.9-1.2
Time in novel zone, hab. session 10.80.91.60.6-0.90.70.7-0.70.9-1.1-1.01.21.0-1.01.3
Total zone transitions, hab. session 12.73.84.81.1-2.12.22.2-2.22.0-2.0-2.11.82.1-2.01.3
Total locomotion distance, hab. session 10.50.71.2-0.7-0.90.90.9-0.90.8-0.6-0.70.50.9-0.61.1
Locomotion velocity, hab. session 10.60.91.7-0.8-1.01.01.0-1.00.9-0.7-0.90.71.0-0.81.3
Time in familiar zone, hab. session 22.02.22.8-0.51.5-1.5-1.51.6-1.51.51.6-1.5-1.61.4-1.7
Time in novel zone, hab. session 22.12.32.91.5-1.71.51.6-1.61.6-1.6-1.61.51.6-1.11.2
Total zone transitions, hab. session 20.10.10.3-0.50.2-0.3-0.20.2-0.30.40.3-0.5-0.30.1-0.4
Total locomotion distance, hab. session 20.60.82.2-1.50.8-0.8-0.80.7-0.81.00.9-1.1-0.80.8-0.2
Locomotion velocity, hab. session 20.50.72.6-1.60.7-0.7-0.70.7-0.71.00.8-1.0-0.70.7-0.0
Novel to familiar place preference ratio0.20.31.91.4-0.30.40.5-0.50.3-0.2-0.10.20.00.1-0.9
Novelty place preference0.20.31.61.3-0.20.30.3-0.30.1-0.00.1-0.0-0.20.3-1.0
Time in novel zone, NPP test0.30.42.21.5-0.20.30.4-0.40.2-0.00.1-0.1-0.20.4-1.2
Total zone transitions, NPP test0.60.91.40.5-1.11.11.2-1.11.1-0.9-1.00.71.0-0.80.4
Total locomotion distance, NPP test0.10.20.6-0.7-0.40.40.4-0.40.3-0.2-0.30.20.4-0.20.8
Locomotion velocity, NPP test0.10.10.8-0.9-0.20.30.3-0.30.2-0.0-0.20.00.3-0.10.7
Intraocular pressure0.20.31.9-0.60.1-0.3-0.30.30.1-0.4-0.30.70.3-0.71.4
Delta distance traveled before/after self-admin3.63.95.2-0.62.2-1.9-1.91.9-1.92.12.2-2.1-2.22.3-2.0
Delta ambulatory time before/after self-admin1.52.63.3-0.31.8-1.5-1.51.5-1.51.71.7-1.7-1.81.8-1.7
Parametrial fat weight0.30.73.5-1.91.0-0.8-0.70.8-0.80.70.7-0.6-0.60.20.1
Pavlov. Cond. lever latency1.21.53.01.7-1.51.41.4-1.41.4-1.1-1.20.91.1-0.7-0.1
Pavlov. Cond. magazine entry latency0.10.10.30.5-0.1-0.1-0.00.10.0-0.4-0.30.60.2-0.50.3
Pavlov. Cond. change in total contacts0.20.20.9-0.60.3-0.4-0.30.4-0.3-0.3-0.10.60.0-0.60.9
Pavlov. Cond. index score0.10.10.3-0.40.5-0.6-0.50.5-0.50.10.20.1-0.2-0.20.3
Pavlov. Cond. latency score0.20.30.6-0.70.7-0.8-0.70.7-0.70.30.4-0.1-0.4-0.10.2
Pavlov. Cond. lever contacts1.11.32.0-1.41.4-1.4-1.31.3-1.41.01.1-0.7-1.10.6-0.0
Pavlov. Cond. magazine entry number0.10.20.6-0.30.20.1-0.1-0.0-0.20.60.5-0.7-0.40.6-0.5
Pavlov. Cond. intertrial magazine entries0.91.12.8-1.71.2-1.0-1.11.1-1.21.01.0-0.8-1.00.90.2
Pavlov. Cond. lever-magazine prob. diff.0.10.10.2-0.30.3-0.4-0.30.3-0.3-0.1-0.00.3-0.0-0.40.4
Pavlov. Cond. response bias0.20.30.7-0.60.7-0.8-0.70.8-0.70.40.4-0.2-0.40.30.1
Pavlov. Cond. lever latency1.52.12.91.7-1.61.51.5-1.61.6-1.4-1.51.31.4-1.40.6
Pavlov. Cond. magazine entry latency0.71.02.3-1.51.2-1.1-1.11.1-1.10.90.9-0.8-0.90.7-0.2
Pavlov. Cond. change in total contacts0.10.31.8-1.40.4-0.4-0.30.4-0.40.00.00.2-0.0-0.30.9
Pavlov. Cond. index score0.81.33.6-1.91.3-1.1-1.11.2-1.21.01.0-0.9-1.00.9-0.1
Pavlov. Cond. latency score1.32.14.3-2.11.6-1.5-1.51.5-1.61.41.4-1.3-1.41.2-0.4
Pavlov. Cond. lever contacts1.52.23.1-1.81.6-1.5-1.51.6-1.71.41.5-1.3-1.51.4-0.6
Pavlov. Cond. magazine entry number1.11.53.51.9-1.31.31.3-1.31.3-1.1-1.11.01.1-0.90.2
Pavlov. Cond. intertrial magazine entries0.10.21.01.0-0.40.30.4-0.40.40.1-0.0-0.30.00.5-0.5
Pavlov. Cond. lever-magazine prob. diff.0.91.43.7-1.91.3-1.2-1.21.2-1.31.11.1-1.0-1.10.9-0.2
Pavlov. Cond. response bias0.50.71.9-1.41.0-0.9-0.90.9-1.00.70.8-0.6-0.80.8-0.1
Time in closed arm before self-admin1.22.14.90.5-0.71.41.4-1.41.4-1.5-1.31.81.3-2.21.8
Time in closed arm after self-admin0.70.83.1-0.8-0.30.30.3-0.30.4-0.7-0.71.10.8-1.51.8
Time in open arm before self-admin0.10.20.80.4-0.0-0.0-0.00.0-0.00.20.1-0.4-0.10.8-0.9
Time in open arm after self-admin0.10.10.40.10.2-0.1-0.10.1-0.20.20.2-0.3-0.20.6-0.4
Bone: periosteal estimation0.30.84.3-2.10.8-0.8-0.70.8-0.90.40.5-0.1-0.4-0.01.1
Bone: periosteal perimeter0.71.37.2-2.71.1-1.1-1.11.0-1.10.60.6-0.2-0.60.11.5
Bone: post-yield work0.30.61.00.9-0.90.80.6-0.70.7-0.8-0.90.60.8-1.0-0.1
Progressive ratio test 1 active lever presses0.10.21.40.30.2-0.1-0.00.1-0.20.40.3-0.5-0.40.6-1.2
Progressive ratio test 1 breakpoint0.10.21.20.40.1-0.00.10.0-0.10.30.3-0.4-0.30.5-1.1
Progressive ratio test 1 inactive lever presses0.00.10.5-0.70.4-0.3-0.30.3-0.20.30.3-0.3-0.30.4-0.1
Progressive ratio test 2 active lever presses0.70.91.7-1.01.0-0.9-0.90.9-0.91.01.0-1.0-0.91.3-0.5
Progressive ratio test 2 breakpoint0.50.71.3-0.80.8-0.8-0.70.8-0.80.90.8-0.9-0.81.1-0.3
Progressive ratio test 2 inactive lever presses0.31.02.0-1.40.9-1.0-0.91.0-0.91.00.9-1.0-0.91.2-0.1
Incentive Sensitization - Responses0.41.02.3-1.51.1-1.0-1.01.0-1.11.00.9-0.8-0.91.00.4
Incentive Sensitization - Breakpoint0.40.92.0-1.41.0-1.0-1.01.0-1.00.90.9-0.8-0.80.90.4
Sum of active levers in priming session hrs 5-60.00.00.2-0.10.4-0.1-0.10.1-0.20.10.20.0-0.20.20.2
Progressive ratio0.10.40.8-0.20.6-0.5-0.50.5-0.60.60.7-0.6-0.70.8-0.9
Food seeking constrained by brief footshock2.53.15.5-2.31.8-1.7-1.71.7-1.81.91.8-1.9-1.71.8-0.3
Seeking ratio, punishment vs. effort0.10.21.4-1.0-0.0-0.1-0.10.1-0.1-0.0-0.10.10.2-0.51.2
Retroperitoneal fat weight2.08.716.1-4.03.3-3.2-3.13.1-3.32.92.9-2.5-2.82.6-0.2
Reaction time number correct0.20.91.30.9-1.01.11.1-1.11.0-0.9-0.90.80.9-1.00.4
Reaction time mean minus median0.00.10.5-0.70.3-0.3-0.30.3-0.30.20.2-0.1-0.20.20.1
Reaction time mean minus median AUC0.00.20.4-0.50.3-0.3-0.40.3-0.40.40.4-0.4-0.40.6-0.3
Reaction time num false alarms0.10.10.50.7-0.20.0-0.0-0.00.2-0.4-0.30.50.2-0.20.0
Reaction time num false alarms AUC0.00.10.50.70.1-0.2-0.30.3-0.1-0.10.00.1-0.10.2-0.6
Reaction time trials correct on left0.20.91.30.9-1.01.11.1-1.11.0-0.9-0.90.80.9-1.00.4
Reaction time trials on left0.30.91.30.9-1.01.01.1-1.11.0-0.9-0.90.80.9-0.90.4
Reaction time mean0.10.21.10.80.00.10.1-0.10.0-0.00.0-0.1-0.10.2-1.1
Reaction time mean AUC0.10.20.80.9-0.10.30.2-0.30.2-0.2-0.10.00.00.1-0.9
Median of all reaction times0.20.42.31.30.00.10.1-0.20.00.10.1-0.3-0.20.3-1.5
Reaction time omissions0.10.21.21.1-0.40.10.1-0.10.3-0.4-0.40.40.3-0.1-0.4
Reaction time false alarm rate0.10.20.50.30.4-0.6-0.70.6-0.40.20.3-0.1-0.30.5-0.5
Reaction time premature initiation rate1.72.66.1-2.51.8-1.8-2.01.9-1.81.41.4-1.0-1.30.90.9
Reaction time premature initiations0.30.82.6-1.61.0-1.0-1.01.0-0.90.70.7-0.4-0.60.20.9
Std. dev. reaction times0.10.30.4-0.50.5-0.6-0.60.6-0.50.40.5-0.5-0.50.5-0.6
Reaction time trials completed0.30.91.30.9-1.01.01.1-1.11.0-0.9-0.90.80.9-0.90.4
Reaction time trials AUC0.20.50.90.6-0.80.80.9-0.90.8-0.7-0.70.60.7-0.80.3
Run reversals in cocaine runway, females0.10.20.50.20.2-0.3-0.30.3-0.30.40.4-0.5-0.40.7-0.7
Run reversals in cocaine runway, males1.01.11.60.4-1.01.01.0-1.01.0-1.1-1.11.21.1-0.91.3
Latency to leave start box in cocaine runway1.72.43.3-1.41.6-1.5-1.51.5-1.41.71.7-1.8-1.61.4-1.3
Latency to leave start box in cocaine runway, F4.04.97.1-1.02.2-2.1-2.12.1-2.02.52.4-2.7-2.52.2-2.6
Latency to leave start box in cocaine runway, M0.40.41.6-1.2-0.20.20.2-0.20.2-0.3-0.40.50.5-0.61.3
Std. dev. time between licks in bursts0.40.73.6-1.90.6-0.5-0.60.5-0.70.80.6-0.7-0.50.60.8
Total sessions with >9 infusions0.40.50.8-0.50.7-0.6-0.50.6-0.60.70.7-0.8-0.70.8-0.9
Short access day 1 total inactive lever presses2.95.86.6-2.32.4-2.5-2.52.5-2.32.52.5-2.6-2.42.5-1.8
Short access day 10 total inactive lever presses1.17.411.8-3.42.9-2.9-3.02.9-3.12.82.7-2.5-2.62.3-0.3
Short access day 1 total infusions0.81.72.4-1.01.3-1.2-1.11.2-1.31.41.3-1.5-1.31.6-1.3
Short access day 10 total infusions0.71.21.6-1.01.2-1.1-1.01.1-1.11.21.2-1.2-1.11.3-0.9
Short access total infusions0.71.01.3-1.11.0-1.0-0.91.0-1.01.11.0-1.1-1.01.2-0.8
Short access day 1 locomotion0.91.42.0-0.71.2-1.1-1.11.1-1.11.31.3-1.4-1.31.3-1.2
Short access day 10 total locomotion0.31.41.8-1.11.2-1.3-1.31.3-1.31.21.2-1.2-1.11.0-0.6
Short access total locomotion0.50.80.9-1.00.9-1.0-0.91.0-1.00.90.9-0.9-0.90.8-0.6
One hour access (0.3 mA shock)0.70.82.9-1.70.9-0.8-0.80.8-0.90.90.8-0.8-0.70.80.3
Compulsive drug intake0.00.00.10.1-0.10.00.0-0.00.1-0.1-0.10.20.1-0.30.3
One hour access (shock baseline)0.20.51.7-1.30.7-0.6-0.60.6-0.70.70.6-0.6-0.50.80.3
Social response proportion0.20.31.1-0.1-0.40.30.3-0.30.2-0.6-0.60.70.5-1.00.6
Social responses0.20.21.0-0.3-0.30.20.2-0.20.2-0.5-0.40.70.4-1.00.7
Social time0.60.92.5-0.50.7-0.8-0.80.8-0.81.00.9-1.2-1.00.9-1.6
Soleus weight1.23.44.1-2.01.9-2.0-1.81.9-1.81.91.9-1.9-1.91.8-1.3
Bone: stiffness0.10.10.5-0.2-0.20.40.3-0.40.2-0.3-0.40.30.4-0.70.2
Tibialis anterior weight0.10.20.3-0.00.4-0.4-0.50.6-0.40.40.5-0.4-0.50.5-0.6
Time to tail flick, vehicle, before self-admin1.11.43.0-1.71.2-1.2-1.21.2-1.21.21.1-1.0-1.11.30.3
Time to tail flick, vehicle, after self-admin0.30.61.0-1.01.0-0.7-0.70.7-0.70.80.8-0.7-0.80.3-0.1
Time to tail flick, test, before self-admin0.40.50.8-0.70.9-0.8-0.80.8-0.80.60.7-0.5-0.70.0-0.4
Time to tail flick, test, after self-admin3.73.94.9-1.42.2-2.0-2.02.0-2.02.12.1-2.1-2.11.9-1.6
Delta time to tail flick, vehicle, before/after SA0.60.61.21.1-0.70.80.8-0.80.8-0.7-0.70.70.7-1.0-0.1
Delta time to tail flick, test, before/after SA0.30.30.9-0.20.4-0.4-0.40.4-0.40.60.6-0.8-0.61.0-0.5
Tibia length1.23.44.31.2-1.92.12.0-2.11.8-1.9-2.01.72.0-2.01.2
Ambulatory time before self-admin0.10.30.60.3-0.80.60.6-0.60.5-0.5-0.50.40.5-0.8-0.5
Ambulatory time after self-admin0.20.31.80.30.4-0.3-0.30.3-0.30.50.6-0.5-0.60.6-1.3
Bone: tissue strength1.31.42.71.6-1.41.41.5-1.41.5-0.8-1.00.51.0-0.5-0.2
Total heroin consumption0.10.10.3-0.50.2-0.2-0.20.2-0.20.10.1-0.0-0.10.40.6
Bone: trabecular number0.91.74.62.1-1.31.41.4-1.41.5-1.2-1.11.21.1-0.40.6
Bone: trabecular spacing1.92.85.3-2.31.7-1.7-1.81.8-1.81.71.6-1.7-1.61.1-0.8
Bone: trabecular thickness0.20.31.1-0.4-0.30.30.3-0.40.5-0.5-0.50.70.5-0.61.1
Bone: trabecular tissue density1.32.23.40.7-1.41.61.7-1.71.4-1.6-1.61.41.5-1.91.1
Water consumed over 24 hours0.10.20.5-0.70.4-0.3-0.20.3-0.40.60.4-0.7-0.40.6-0.4
Number of responses in last shaping day0.10.10.50.7-0.30.20.2-0.20.3-0.2-0.20.00.20.1-0.6