Hub : Genes

H2-Q7-ps1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr20_2631404_2662623 0.2 0.12 1.0e-06 0.03 0.03 0.02 0.02 2.8e-04 2.3e-04 1.4e-03 8.6e-04
2 Adipose intron excision ratio chr20_2675633_2675825 0.27 0.14 3.6e-09 0.06 0.06 0.05 0.06 6.5e-07 3.3e-07 1.1e-06 9.0e-07
3 Adipose intron excision ratio chr20_2629035_2629238 0.35 0.14 6.9e-14 0.01 0.05 0.04 0.04 2.5e-02 3.8e-06 2.8e-05 4.7e-05
4 Adipose intron excision ratio chr20_2637860_2638063 0.35 0.14 6.9e-14 0.01 0.05 0.04 0.04 2.5e-02 3.8e-06 2.8e-05 4.8e-05
5 Adipose intron excision ratio chr20_2622575_2622726 0.05 0.04 3.1e-03 0.02 0 -0 0.01 5.8e-03 1.2e-01 5.2e-01 5.3e-02
6 Adipose intron excision ratio chr20_2622575_2631555 0.05 0.04 3.5e-03 0.02 0 -0 0.01 5.8e-03 1.1e-01 5.4e-01 5.6e-02
7 Eye intron excision ratio chr20_2631404_2662623 0.76 0.14 7.8e-06 0.05 0.19 0.08 0.14 5.9e-02 7.7e-04 2.2e-02 3.3e-03
8 Adipose intron excision ratio chr20_2631404_2640514 0.23 0.12 1.8e-08 0.02 0.04 0.04 0.04 1.3e-03 2.7e-05 1.5e-05 1.2e-05
9 IL gene expression H2-Q7-ps1 0.61 0.14 1.6e-14 0.4 0.42 0.41 0.42 9.5e-11 3.9e-11 5.0e-11 2.1e-11
10 Liver gene expression H2-Q7-ps1 0.52 0.09 0.0e+00 0.59 0.58 0.59 0.6 1.2e-81 9.7e-79 5.6e-81 3.1e-84
11 Adipose gene expression H2-Q7-ps1 0.39 0.11 0.0e+00 0.48 0.47 0.49 0.48 3.3e-59 4.6e-59 4.1e-62 7.5e-61
12 NAcc gene expression H2-Q7-ps1 0.29 0.09 0.0e+00 0.35 0.36 0.37 0.37 4.5e-55 2.4e-57 1.3e-58 1.3e-58
13 Eye gene expression H2-Q7-ps1 0.33 0.19 3.5e-03 0.04 0.06 0.05 0.07 7.8e-02 4.2e-02 6.9e-02 2.9e-02
14 PL gene expression H2-Q7-ps1 0.48 0.11 0.0e+00 0.56 0.56 0.56 0.56 2.6e-74 7.5e-73 9.6e-75 1.1e-73
15 LHb gene expression H2-Q7-ps1 0.47 0.24 1.2e-07 0.22 0.25 0.26 0.23 6.4e-06 9.7e-07 8.3e-07 3.1e-06
16 BLA gene expression H2-Q7-ps1 0.68 0.14 0.0e+00 0.5 0.52 0.52 0.52 2.4e-30 5.3e-32 1.8e-31 1.8e-31
17 OFC gene expression H2-Q7-ps1 0.61 0.14 1.7e-14 0.35 0.35 0.4 0.41 3.2e-09 4.7e-09 1.2e-10 8.2e-11
18 Brain gene expression H2-Q7-ps1 0.33 0.13 0.0e+00 0.31 0.31 0.32 0.32 1.7e-29 1.1e-29 1.2e-30 3.3e-30
19 IC gene expression H2-Q7-ps1 0.57 0.1 0.0e+00 0.3 0.41 0.39 0.35 5.2e-13 2.1e-18 1.4e-17 1.6e-15
20 NAcc intron excision ratio chr20_2631404_2662623 0.02 0.02 5.0e-03 0.01 0 0 0 3.7e-02 2.1e-01 3.3e-01 3.7e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.52.64.01.7-1.71.81.8-1.4-1.41.92.01.61.71.71.70.91.61.01.61.71.51.4-1.7
Area under the delay curve1.31.52.7-0.50.3-0.6-0.6-0.1-0.1-0.8-1.1-1.5-1.6-1.5-1.6-1.0-1.3-1.5-1.5-1.5-1.6-1.61.6
BMI with tail0.82.96.20.8-1.00.40.4-1.6-1.60.20.0-1.9-1.9-1.9-1.9-2.4-2.0-2.5-1.7-1.9-2.1-2.21.8
BMI without tail2.16.312.4-0.20.1-0.8-0.8-0.9-0.9-0.9-1.2-3.0-3.4-3.1-3.1-3.5-3.2-3.5-2.9-3.0-3.2-3.42.6
Body weight5.624.635.9-3.63.5-4.4-4.42.12.1-4.6-4.6-5.9-6.0-5.9-5.9-4.4-5.9-5.2-5.8-5.7-5.5-5.65.4
Weight adjusted by age2.43.64.8-1.81.8-2.1-2.11.51.5-2.1-1.9-2.0-2.0-2.2-2.0-0.7-1.9-1.6-2.2-2.2-2.0-1.92.1
Bone surface0.20.40.9-0.91.0-0.9-0.90.60.6-0.8-0.8-0.6-0.5-0.4-0.4-0.0-0.5-0.2-0.5-0.3-0.3-0.3-0.1
Bone volume0.00.00.20.1-0.0-0.0-0.0-0.0-0.00.00.1-0.3-0.3-0.2-0.2-0.3-0.3-0.4-0.2-0.1-0.3-0.3-0.0
Breakpoint value in progressive ratio session0.20.20.60.2-0.10.30.3-0.0-0.00.30.30.70.60.60.7-0.30.80.70.70.60.70.7-0.3
Number of licking bursts0.30.41.1-0.90.9-0.7-0.71.11.1-0.6-0.60.30.40.40.40.90.40.80.40.40.60.6-0.5
Context. condit. distance diff. score4.35.211.5-0.81.0-0.3-0.31.91.9-0.00.32.42.52.62.63.42.63.42.52.73.03.0-2.8
Locomotion velocity, session 10.20.30.8-0.50.5-0.3-0.30.50.5-0.3-0.00.30.50.50.50.90.40.80.40.40.60.6-0.4
Locomotion distance, session 10.91.12.61.4-1.41.41.4-1.6-1.61.31.50.80.80.70.90.00.70.20.80.70.50.5-0.4
Locomotion velocity, session 20.10.10.2-0.50.4-0.4-0.40.30.3-0.4-0.1-0.0-0.0-0.0-0.00.30.00.2-0.0-0.10.00.10.3
Locomotion distance, session 20.30.40.80.6-0.70.70.7-0.8-0.80.70.90.70.70.60.70.50.70.50.70.50.50.6-0.2
Locomotion velocity, session 30.20.30.90.9-0.70.60.6-0.9-0.90.60.8-0.00.0-0.00.0-0.5-0.1-0.4-0.0-0.1-0.2-0.30.0
Locomotion distance, session 31.31.42.00.9-0.81.01.0-0.6-0.61.11.31.41.21.41.40.91.31.21.41.41.31.3-1.4
Stereotopy head waving bouts, day 32.22.64.0-1.81.9-2.0-2.01.51.5-2.0-1.8-1.6-1.6-1.6-1.6-0.7-1.5-1.0-1.6-1.6-1.4-1.21.6
Stereotopy head waving duration, day 31.41.72.3-1.41.4-1.5-1.51.01.0-1.5-1.4-1.4-1.4-1.4-1.4-0.7-1.3-0.9-1.3-1.4-1.2-1.11.5
Locomotion velocity, session 73.74.06.20.9-0.91.31.3-0.5-0.51.51.52.42.42.42.42.32.42.42.42.52.52.4-2.4
Locomotion distance, session 73.54.56.81.5-1.51.91.9-1.0-1.02.02.02.52.42.52.42.02.42.12.42.52.42.3-2.6
Stereotopy head waving bouts, day 72.73.04.5-1.11.3-1.5-1.50.80.8-1.6-1.3-2.0-2.1-2.1-2.0-1.6-2.0-1.8-2.0-2.1-2.0-1.92.1
Stereotopy head waving duration, day 72.63.14.7-1.21.3-1.6-1.60.80.8-1.6-1.5-2.1-2.2-2.1-2.0-1.6-2.0-1.8-2.1-2.1-2.1-1.92.1
Locomotion velocity, session 82.32.88.2-2.72.7-2.4-2.42.92.9-2.3-1.9-0.3-0.3-0.3-0.21.4-0.11.1-0.3-0.30.20.50.5
Locomotion distance, session 82.23.27.4-0.50.7-0.1-0.11.31.30.10.52.02.12.12.12.72.12.72.02.12.42.4-2.0
Degree of sensitization distance0.40.41.2-0.70.6-0.4-0.40.90.9-0.4-0.50.40.60.50.41.10.50.90.40.50.60.7-0.6
Degree of sensitization stereotypy1.01.11.7-0.40.6-0.8-0.80.10.1-0.8-0.6-1.2-1.3-1.3-1.2-1.1-1.2-1.2-1.3-1.3-1.3-1.21.3
Conditioned locomotion0.81.02.0-1.10.9-1.0-1.00.40.4-1.1-1.4-1.0-1.0-1.1-1.1-0.5-0.9-0.7-1.0-1.1-1.0-0.81.4
Cocaine response after cond. corrected0.50.60.90.7-0.60.70.7-0.5-0.50.80.90.90.90.90.90.60.90.70.91.00.90.8-0.7
Cocaine response after cond. not corrected0.30.30.9-0.90.9-0.9-0.90.70.7-0.9-0.8-0.4-0.3-0.3-0.40.1-0.30.1-0.4-0.3-0.2-0.10.5
Cocaine response before conditioning5.86.99.6-2.82.6-2.9-2.91.91.9-3.0-3.1-2.9-2.8-2.8-2.8-1.6-2.8-1.9-2.8-2.9-2.5-2.42.6
Saline control response1.21.63.70.7-0.80.40.4-1.4-1.40.30.0-1.3-1.3-1.3-1.4-1.9-1.4-1.9-1.2-1.3-1.6-1.71.0
Bone: connectivity density2.13.34.81.2-1.11.41.4-0.8-0.81.61.72.12.22.22.11.82.11.92.12.22.12.0-2.2
Bone: cortical apparent density0.50.71.81.4-1.31.11.1-0.9-0.90.90.9-0.2-0.3-0.3-0.4-1.0-0.3-1.0-0.3-0.3-0.6-0.70.6
Bone: cortical area1.42.23.3-0.91.0-1.3-1.30.70.7-1.3-1.1-1.8-1.8-1.8-1.7-1.4-1.7-1.6-1.8-1.7-1.7-1.71.6
Bone: cortical porosity0.40.51.0-0.30.2-0.3-0.3-0.1-0.1-0.4-0.2-0.9-1.0-0.9-0.8-0.8-0.9-0.9-0.8-0.9-0.9-0.90.8
Bone: cortical porosity0.60.61.0-0.90.8-0.9-0.90.20.2-0.9-0.8-0.9-1.0-0.9-0.8-0.4-0.9-0.6-0.8-0.9-0.8-0.80.8
Bone: cortical thickness2.03.38.01.2-1.10.50.5-1.3-1.30.30.4-1.9-2.0-2.0-1.9-2.8-2.0-2.8-2.0-2.0-2.4-2.52.0
Bone: cortical thickness1.21.43.91.7-1.71.31.3-2.0-2.01.10.9-0.5-0.6-0.6-0.6-1.5-0.7-1.3-0.6-0.7-1.0-1.10.7
Bone: cortical tissue density0.40.51.61.3-1.21.01.0-0.9-0.90.90.8-0.1-0.3-0.3-0.3-0.9-0.2-0.8-0.3-0.2-0.5-0.60.5
Condit. Reinf. active minus inactive responses0.60.71.30.4-0.40.60.6-0.1-0.10.60.51.01.11.01.00.91.01.01.01.01.01.0-0.7
Condit. Reinf. active-inactive response ratio0.10.10.40.5-0.60.50.5-0.4-0.40.40.20.10.10.0-0.1-0.30.0-0.3-0.0-0.0-0.1-0.10.2
Condit. Reinf. active responses1.11.42.40.7-0.81.01.0-0.4-0.41.01.01.41.61.41.41.21.31.31.31.41.31.3-1.2
Condit. Reinf. inactive responses2.32.94.01.6-1.61.81.8-1.3-1.31.82.01.81.91.81.91.21.71.41.81.81.71.6-1.8
Incentive salience index mean1.01.33.2-0.50.4-0.1-0.10.90.9-0.0-0.01.21.51.31.31.81.31.71.21.31.41.5-1.1
Condit. Reinf. lever presses2.02.97.3-1.01.1-0.5-0.51.71.7-0.3-0.11.71.91.81.82.71.82.51.71.82.12.2-1.7
Condit. Reinf. active minus inactive responses1.11.42.0-1.10.9-1.1-1.10.40.4-1.2-1.3-1.4-1.4-1.4-1.4-0.6-1.3-1.0-1.3-1.4-1.3-1.21.4
Condit. Reinf. active-inactive response ratio2.63.14.4-1.81.6-1.8-1.81.01.0-1.9-2.1-2.0-1.9-1.9-2.0-1.0-1.9-1.4-1.9-2.0-1.7-1.62.0
Condit. Reinf. active responses0.00.00.2-0.30.1-0.1-0.1-0.0-0.0-0.1-0.2-0.00.10.10.00.50.10.30.10.00.10.1-0.2
Condit. Reinf. inactive responses1.51.93.11.0-1.01.21.2-0.5-0.51.31.41.61.61.61.61.31.61.41.61.71.61.5-1.7
Condit. Reinf. lever presses0.50.71.40.3-0.30.50.50.00.00.50.60.90.91.01.11.21.01.01.01.01.11.1-1.1
Condit. Reinf. lever reinforcers received0.00.10.4-0.30.2-0.1-0.10.20.2-0.1-0.10.10.20.20.20.60.20.40.20.20.30.3-0.3
Conditioned reinforcement - actives0.71.23.40.3-0.2-0.1-0.1-0.8-0.8-0.1-0.3-1.2-1.2-1.2-1.1-1.8-1.1-1.7-1.1-1.4-1.5-1.31.3
Conditioned reinforcement - inactives0.81.22.90.4-0.50.10.1-1.2-1.20.10.1-1.2-1.4-1.3-1.2-1.4-1.2-1.7-1.1-1.3-1.4-1.41.4
Conditioned locomotion0.20.30.7-0.50.3-0.5-0.50.20.2-0.4-0.8-0.7-0.4-0.6-0.6-0.7-0.5-0.5-0.6-0.8-0.7-0.50.7
Patch foraging indifference point 0 sec0.51.02.71.6-1.31.11.1-1.7-1.71.11.4-0.2-0.6-0.4-0.2-1.4-0.4-1.0-0.2-0.2-0.6-0.70.3
Patch foraging indifference point AUC1.01.42.7-0.90.8-1.0-1.00.40.4-1.1-1.1-1.6-1.3-1.4-1.6-0.8-1.6-1.2-1.5-1.4-1.3-1.40.9
Delay disc. indifference point, 0s delay0.60.71.4-0.90.8-0.9-0.90.70.7-1.0-1.2-0.8-1.0-0.8-0.9-0.5-0.7-0.5-0.8-0.8-0.8-0.70.9
Delay disc. indifference point, 16s delay1.61.73.61.1-1.20.80.8-1.8-1.80.60.4-1.2-1.3-1.2-1.3-1.7-1.1-1.9-1.2-1.2-1.5-1.61.2
Delay disc. indifference point, 2s delay1.71.92.9-1.11.1-1.3-1.30.70.7-1.4-1.6-1.4-1.6-1.6-1.6-1.2-1.5-1.3-1.5-1.6-1.5-1.41.7
Delay disc. indifference point, 24s delay0.30.30.90.4-0.50.30.3-0.8-0.80.20.0-0.6-0.6-0.6-0.6-1.0-0.5-0.8-0.5-0.5-0.7-0.70.5
Delay disc. indifference point, 4s delay3.23.45.6-1.61.4-1.7-1.71.01.0-1.9-2.2-2.1-2.1-2.1-2.1-1.1-1.9-1.8-2.1-2.1-2.0-1.92.4
Delay disc. indifference point, 8s delay0.20.20.5-0.1-0.0-0.1-0.1-0.1-0.1-0.2-0.3-0.5-0.7-0.6-0.7-0.0-0.4-0.6-0.6-0.6-0.7-0.70.7
Indifference point function ln k0.20.30.9-0.40.5-0.3-0.30.70.7-0.20.10.50.40.50.70.80.60.90.50.40.50.7-0.3
Indifference point function log k0.20.30.9-0.40.5-0.3-0.30.70.7-0.20.10.50.40.50.70.80.60.90.50.40.50.7-0.3
Patch foraging total patch changes 0 sec0.71.23.11.7-1.41.11.1-1.8-1.81.11.5-0.4-0.8-0.5-0.4-1.7-0.6-1.3-0.4-0.3-0.8-1.00.4
Patch foraging total patch changes 12 sec0.81.13.01.3-1.31.01.0-1.7-1.70.90.7-0.7-0.8-0.7-0.7-1.4-0.9-1.3-0.6-0.6-0.9-1.10.5
Patch foraging total patch changes 18 sec1.31.95.82.4-2.21.91.9-2.2-2.21.92.30.1-0.00.20.2-1.1-0.1-0.80.20.3-0.1-0.4-0.4
Patch foraging total patch changes 24 sec1.83.17.62.7-2.72.62.6-2.7-2.72.52.41.10.70.90.9-0.50.8-0.21.01.10.60.3-0.9
Patch foraging total patch changes 6 sec1.11.75.71.9-1.91.61.6-2.4-2.41.51.3-0.3-0.6-0.4-0.5-1.4-0.5-1.4-0.3-0.3-0.7-0.90.3
Patch foraging time to switch 0 sec0.51.02.21.5-1.51.41.4-1.3-1.31.41.10.80.60.70.6-0.10.70.20.70.70.50.4-0.3
Patch foraging water rate 0 sec0.30.61.1-0.20.0-0.3-0.3-0.3-0.3-0.4-0.2-0.9-0.9-1.0-0.9-0.7-1.0-1.0-0.9-1.0-1.0-1.01.0
Patch foraging water rate 12 sec0.20.31.00.9-1.00.90.9-0.8-0.80.90.80.20.40.10.20.10.1-0.40.20.0-0.1-0.00.2
Patch foraging water rate 18 sec0.20.40.6-0.70.6-0.7-0.7-0.3-0.3-0.7-0.5-0.7-0.7-0.7-0.60.0-0.6-0.6-0.6-0.6-0.6-0.60.8
Patch foraging water rate 24 sec1.11.52.9-0.40.4-0.7-0.7-0.3-0.3-0.7-0.4-1.7-1.5-1.6-1.5-1.0-1.7-1.5-1.6-1.6-1.7-1.61.4
Patch foraging water rate 6 sec0.20.30.90.7-0.90.70.7-0.9-0.90.70.8-0.1-0.1-0.0-0.0-0.0-0.1-0.5-0.0-0.1-0.2-0.3-0.1
Seeking ratio, delayed vs. immediate footshock0.40.50.9-0.70.6-0.7-0.70.40.4-0.8-0.9-0.8-0.8-0.8-0.8-0.5-0.7-0.7-0.8-0.8-0.8-0.71.0
Distance traveled before self-admin0.60.82.2-1.31.4-1.3-1.31.51.5-1.3-1.0-0.3-0.4-0.5-0.40.0-0.40.2-0.5-0.6-0.4-0.10.6
Distance traveled after self-admin1.51.83.0-1.41.7-1.7-1.71.51.5-1.6-1.4-1.1-1.2-1.2-1.2-1.2-1.2-0.9-1.3-1.3-1.0-1.01.0
Extensor digitorum longus weight0.10.51.5-1.11.2-1.1-1.11.21.2-0.9-0.8-0.4-0.2-0.1-0.20.3-0.20.3-0.10.00.10.0-0.5
Bone: elastic displacement0.30.40.90.7-0.80.60.6-0.9-0.90.50.3-0.3-0.4-0.4-0.3-0.9-0.4-0.9-0.3-0.4-0.5-0.60.5
Bone: elastic work1.51.93.9-0.20.2-0.6-0.6-0.2-0.2-0.7-0.5-1.7-1.7-1.7-1.6-1.8-1.7-2.0-1.7-1.7-1.8-1.81.7
Bone: endosteal estimation4.18.919.8-4.44.3-4.3-4.33.53.5-4.2-4.1-2.5-2.3-2.2-2.2-0.0-2.1-0.6-2.2-2.2-1.6-1.41.8
Bone: endosteal perimeter1.83.811.6-3.43.3-2.9-2.93.03.0-2.7-2.6-0.5-0.4-0.2-0.31.6-0.21.2-0.3-0.20.40.5-0.0
Epididymis fat weight3.913.539.55.6-5.84.84.8-6.3-6.34.43.9-0.6-1.2-0.9-1.1-4.2-1.1-3.5-0.7-0.7-1.9-2.31.3
Delta time in closed arm before/after self-admin0.20.20.5-0.1-0.0-0.1-0.1-0.2-0.2-0.2-0.4-0.6-0.7-0.6-0.6-0.4-0.5-0.6-0.6-0.6-0.6-0.70.5
Delta time in open arm before/after self-admin0.40.41.2-0.50.6-0.6-0.60.40.4-0.7-0.5-0.5-0.5-0.7-0.6-0.7-0.6-0.5-0.6-0.8-0.8-0.51.1
Diff in mean of infusions in LGA sessions4.04.97.12.0-1.92.32.3-1.4-1.42.32.22.72.42.52.51.02.62.12.62.42.32.4-2.1
Delay discount exponential model param1.41.52.80.5-0.30.60.60.10.10.81.11.51.61.61.61.01.41.51.51.51.61.6-1.7
Extinction: sum of active levers before priming0.50.61.40.5-0.30.60.6-0.6-0.60.60.81.20.60.90.90.10.90.60.91.00.90.9-0.7
Active lever presses in extinction session 60.60.61.61.1-1.21.11.1-1.3-1.31.10.90.50.40.50.4-0.40.5-0.00.50.60.30.2-0.6
Bone: final force3.65.810.9-0.40.4-1.0-1.0-0.4-0.4-1.2-1.2-3.0-3.1-3.0-3.0-3.1-3.0-3.3-2.9-2.9-3.2-3.22.6
Bone: final moment3.25.29.4-0.50.5-1.1-1.1-0.2-0.2-1.2-1.2-2.9-2.9-2.8-2.8-2.9-2.8-3.1-2.8-2.7-3.0-3.02.5
Food consumed during 24 hour testing period1.21.62.8-1.71.6-1.7-1.71.61.6-1.6-1.6-1.2-1.0-1.1-1.0-0.1-1.0-0.5-1.1-1.1-0.9-0.81.0
Glucose2.23.58.9-2.82.8-2.3-2.33.03.0-2.2-1.90.40.60.60.62.50.72.10.50.61.21.4-0.4
Heart weight1.32.04.6-0.50.6-0.9-0.9-0.0-0.0-0.9-1.0-1.8-1.5-1.7-1.8-2.1-1.9-1.7-1.7-1.7-1.7-1.81.3
Delay discount hyperbolic model param1.51.63.00.5-0.30.70.70.10.10.81.11.51.71.61.71.01.41.61.61.61.71.6-1.7
Intermittent access intake day 1-15 change0.00.10.3-0.30.1-0.1-0.10.20.2-0.1-0.40.10.60.20.20.50.00.20.1-0.00.10.2-0.2
Intermittent access intake escalation0.00.10.2-0.1-0.1-0.0-0.0-0.2-0.2-0.0-0.4-0.30.2-0.2-0.20.0-0.4-0.3-0.3-0.4-0.3-0.30.2
Intermittent access intake escalation 20.70.72.0-1.41.3-1.2-1.21.31.3-1.1-1.3-0.40.2-0.2-0.21.1-0.40.4-0.4-0.3-0.0-0.0-0.0
Intermitt. access day 1 inactive lever presses0.31.02.6-1.41.5-1.5-1.51.61.6-1.3-0.9-0.7-0.5-0.8-0.60.3-0.8-0.3-0.8-0.8-0.4-0.50.6
Intermitt. access day 15 inactive lever presses0.71.42.9-0.91.0-1.2-1.20.90.9-1.1-0.6-1.7-1.2-1.3-1.3-0.6-1.6-1.2-1.3-1.3-1.2-1.30.9
Intermitt. access escalation Index1.82.64.90.5-0.61.01.0-0.2-0.21.00.92.11.92.02.01.92.21.92.12.12.02.1-1.8
Intermittent access day 1 total infusions0.60.92.81.4-1.21.21.2-1.6-1.61.11.10.50.10.40.4-1.70.6-0.20.60.60.20.3-0.1
Intermittent access day 15 total infusions0.30.42.00.7-0.80.70.7-1.2-1.20.50.1-0.1-0.1-0.1-0.2-1.40.0-0.7-0.0-0.2-0.4-0.20.4
Intermittent access terminal intake (last 3 days)0.50.63.10.8-0.80.60.6-1.3-1.30.50.1-0.5-0.5-0.5-0.5-1.8-0.4-1.1-0.4-0.5-0.7-0.60.7
Intermittent access total infusions0.40.42.80.7-0.60.50.5-1.1-1.10.40.1-0.3-0.4-0.3-0.4-1.7-0.2-0.8-0.2-0.2-0.6-0.40.5
Intermittent access day 1 locomotion0.10.11.10.2-0.20.30.3-0.2-0.20.2-0.20.20.00.20.1-1.10.50.00.30.20.10.30.1
Intermittent access day 15 total locomotion1.22.23.9-1.31.1-1.3-1.30.70.7-1.4-2.0-1.8-1.4-1.6-1.6-1.5-1.4-1.5-1.6-1.7-1.6-1.41.7
Intermittent access total locomotion1.41.62.9-1.00.8-1.0-1.00.60.6-1.1-1.7-1.5-1.3-1.4-1.4-1.7-1.2-1.4-1.3-1.5-1.4-1.31.6
Intermittent access standard deviation1.02.04.60.1-0.0-0.4-0.4-0.4-0.4-0.4-0.6-1.9-1.4-1.7-1.7-2.1-1.9-2.0-1.7-1.7-1.9-1.91.6
Left kidney weight3.717.126.1-2.32.2-3.1-3.11.01.0-3.3-3.5-5.0-4.9-5.0-5.0-4.4-5.1-4.6-4.9-5.1-5.1-4.94.6
Right kidney weight4.319.628.4-2.92.8-3.6-3.61.81.8-3.8-4.2-5.3-5.2-5.3-5.3-4.2-5.2-4.8-5.2-5.3-5.2-5.14.8
Cocaine induced anxiety0.60.83.0-0.70.7-0.5-0.51.71.7-0.4-0.20.90.70.60.71.10.81.20.70.60.90.9-0.7
Post-drug Anxiety0.50.61.4-0.10.10.10.11.11.10.10.40.90.70.80.71.00.71.20.80.90.90.8-0.9
Baseline Anxiety1.31.53.81.6-1.71.61.6-1.9-1.91.61.50.80.80.90.80.40.70.40.91.00.70.6-0.9
Tail length5.420.930.4-5.05.1-5.5-5.54.24.2-5.5-5.4-4.6-4.7-4.7-4.6-2.3-4.6-3.1-4.7-4.5-4.0-3.94.0
Length with tail7.532.547.3-6.36.4-6.8-6.85.15.1-6.9-6.7-5.9-5.8-5.8-5.7-2.8-5.7-3.9-5.8-5.6-5.0-4.95.1
Length without tail5.718.423.4-4.24.3-4.7-4.73.13.1-4.8-4.6-4.8-4.5-4.7-4.6-2.6-4.6-3.4-4.7-4.6-4.2-4.14.4
Times rat made contact with spout2.32.64.62.1-2.12.12.1-1.8-1.82.12.01.41.41.41.50.21.30.51.41.41.10.9-1.6
Lifetime Intake0.50.63.80.5-0.40.30.3-0.9-0.90.2-0.1-0.5-0.8-0.6-0.6-1.9-0.4-1.1-0.5-0.6-0.9-0.70.8
Liver weight, left2.64.310.3-3.13.1-2.9-2.93.23.2-2.9-2.9-1.2-1.1-1.1-1.10.5-0.9-0.0-1.1-1.2-0.7-0.41.2
Liver weight, right4.47.714.9-3.73.7-3.7-3.73.33.3-3.7-3.9-2.4-2.4-2.4-2.4-0.7-2.2-1.1-2.3-2.3-1.8-1.62.1
Locomotor activity2.53.910.4-3.23.0-3.0-3.02.42.4-2.8-2.7-1.4-1.3-1.2-1.21.1-1.30.1-1.3-1.2-0.7-0.71.0
Locomotor testing distance0.50.92.8-1.71.6-1.5-1.51.21.2-1.4-1.2-0.5-0.5-0.3-0.31.2-0.40.4-0.4-0.2-0.0-0.10.0
Locomotor testing rearing0.61.23.0-1.71.6-1.6-1.61.11.1-1.6-1.5-0.9-0.9-0.8-0.80.2-0.8-0.0-0.8-0.9-0.6-0.50.8
Locomotion in novel chamber0.60.81.8-0.50.6-0.8-0.80.20.2-0.7-0.5-1.4-1.0-1.0-1.0-0.9-1.0-1.0-1.0-0.9-1.2-1.00.5
Locomotion in novel chamber post-restriction0.50.82.0-0.0-0.0-0.3-0.3-0.2-0.2-0.3-0.5-1.1-1.1-1.1-1.1-0.6-1.1-1.4-1.1-1.0-1.3-1.21.3
Fecal boli incidents, locomotor time 10.50.81.40.8-0.40.70.7-0.4-0.40.81.10.91.11.11.2-0.11.10.61.11.01.01.0-1.1
Change in fecal boli incidents, locomotor task0.80.81.3-0.80.6-0.8-0.80.70.7-0.9-1.0-0.9-0.8-1.0-1.1-0.6-1.1-0.6-1.1-0.8-0.8-1.01.1
Time >=10cm from walls, locomotor time 11.21.32.5-1.51.6-1.6-1.61.41.4-1.5-1.5-0.9-0.8-0.9-0.8-0.4-0.8-0.6-0.9-0.9-0.6-0.60.9
Bouts of movement, locomotor time 10.60.72.8-0.50.4-0.2-0.20.80.8-0.2-0.10.51.10.90.91.71.01.30.90.80.81.0-0.9
Total resting periods, locomotor time 10.40.41.2-0.70.7-0.5-0.50.90.9-0.4-0.40.20.70.50.51.10.60.90.50.50.50.7-0.4
Rest time, locomotor task time 10.70.93.0-1.41.3-1.3-1.31.71.7-1.3-1.4-0.5-0.2-0.5-0.50.2-0.30.1-0.5-0.4-0.2-0.20.6
Distance moved, locomotor task time 10.30.41.40.5-0.40.20.2-0.9-0.90.20.2-0.5-0.7-0.6-0.6-1.0-0.8-1.2-0.6-0.8-0.8-0.80.4
Vertical activity count, locomotor time 10.10.20.80.4-0.40.20.2-0.9-0.90.20.3-0.3-0.6-0.4-0.5-0.2-0.6-0.7-0.4-0.5-0.5-0.60.3
Time >=10cm from walls, locomotor time 20.20.31.1-0.90.8-0.7-0.70.90.9-0.8-1.1-0.1-0.2-0.2-0.3-0.0-0.00.2-0.2-0.1-0.00.00.4
Bouts of movement, locomotor time 21.21.94.9-2.21.8-1.9-1.92.12.1-1.9-2.0-1.0-0.8-0.8-0.90.9-0.60.1-0.8-0.8-0.6-0.41.2
Total resting periods, locomotor time 21.32.36.1-2.52.1-2.0-2.02.42.4-2.0-2.2-0.9-0.7-0.7-0.71.3-0.40.4-0.7-0.6-0.4-0.21.0
Rest time, locomotor task time 21.92.48.7-2.32.3-2.0-2.02.92.9-1.8-1.8-0.20.40.20.21.70.41.30.00.10.40.7-0.1
Distance moved, locomotor task time 21.11.33.61.3-1.41.01.0-1.9-1.90.90.5-0.4-0.8-0.8-0.8-1.6-0.9-1.5-0.7-0.7-1.0-1.10.7
Vertical activity count, locomotor time 20.30.41.30.9-1.10.90.9-1.2-1.20.80.60.3-0.1-0.1-0.2-0.0-0.2-0.4-0.00.1-0.0-0.30.0
Light reinforcement 10.10.31.10.9-0.80.70.7-1.0-1.00.60.70.1-0.2-0.1-0.1-0.8-0.1-0.3-0.10.1-0.1-0.30.2
Light reinforcement 20.81.22.2-1.21.1-1.2-1.21.11.1-1.4-1.5-0.9-1.1-1.2-1.2-0.6-1.0-0.5-1.2-1.0-0.9-0.91.4
Bone: marrow area4.08.719.3-4.44.3-4.2-4.23.43.4-4.1-4.1-2.5-2.3-2.2-2.2-0.0-2.1-0.6-2.2-2.1-1.6-1.41.8
Bone: maximum diameter1.32.46.6-2.52.6-2.4-2.42.02.0-2.3-2.0-1.1-0.9-0.8-0.80.4-0.80.1-0.8-0.8-0.4-0.30.5
Bone: maximum force3.05.49.1-0.90.8-1.4-1.4-0.0-0.0-1.5-1.6-2.9-2.9-2.8-2.9-2.7-2.8-3.0-2.8-2.8-3.0-3.02.5
Bone: maximum moment2.84.97.9-1.11.0-1.5-1.50.30.3-1.6-1.6-2.8-2.8-2.7-2.7-2.5-2.7-2.8-2.7-2.6-2.8-2.82.4
Mean time between licks in bursts1.02.48.2-2.42.4-2.1-2.12.92.9-2.0-1.8-0.1-0.0-0.00.01.40.11.1-0.10.00.50.60.0
Mean num. licks in bursts0.81.33.61.8-1.81.61.6-1.9-1.91.61.50.40.40.40.3-0.70.2-0.40.40.4-0.1-0.1-0.3
Cd content in liver0.50.62.30.8-1.21.11.1-1.5-1.51.00.50.50.10.20.2-0.20.5-0.10.40.20.10.20.4
Co content in liver0.91.03.01.0-1.30.90.9-1.7-1.70.80.7-0.5-0.7-0.7-0.6-1.3-0.6-1.3-0.5-0.7-0.9-1.00.8
Cu content in liver3.33.96.42.4-2.52.52.5-2.3-2.32.52.41.91.71.81.80.81.70.91.81.81.51.4-1.9
Fe content in liver0.60.71.90.6-0.90.60.6-1.4-1.40.40.2-0.7-0.6-0.7-0.8-1.1-0.8-1.1-0.6-0.7-0.9-1.00.7
K content in liver0.40.31.50.9-0.60.60.6-0.0-0.00.71.20.40.50.50.60.40.30.20.40.50.40.3-1.1
Mg content in liver0.80.82.2-0.30.4-0.1-0.10.80.80.00.20.91.01.01.01.40.91.30.91.11.21.1-1.5
Mn content in liver2.22.46.2-1.61.7-1.2-1.22.12.1-1.0-0.61.11.41.31.32.51.22.21.21.31.71.7-1.6
Na content in liver0.50.51.51.0-1.10.90.9-1.2-1.20.80.7-0.4-0.2-0.3-0.3-0.8-0.5-1.0-0.3-0.3-0.5-0.70.0
Rb content in liver1.11.23.20.6-0.81.01.0-0.9-0.91.00.91.11.11.31.11.11.11.11.31.31.31.1-1.8
Se content in liver1.21.54.2-2.11.8-1.5-1.51.91.9-1.5-1.70.20.40.30.31.70.41.00.20.30.60.7-0.2
Sr content in liver0.80.71.2-1.11.0-1.1-1.10.90.9-1.0-1.1-0.8-0.8-0.8-0.7-0.3-0.7-0.5-0.8-0.7-0.7-0.60.8
Zn content in liver0.10.10.1-0.30.3-0.2-0.20.30.3-0.1-0.10.10.10.20.20.40.10.30.20.20.30.3-0.4
Bone: minimum diameter2.03.68.9-2.93.0-2.8-2.82.92.9-2.7-2.4-1.2-1.1-1.0-1.00.6-1.00.2-1.1-1.0-0.6-0.40.8
Time in familiar zone, hab. session 14.03.96.52.4-2.42.62.6-1.7-1.72.52.42.11.81.91.90.71.91.11.91.91.61.5-1.5
Time in novel zone, hab. session 12.32.34.5-2.12.1-2.1-2.11.11.1-2.0-2.1-1.5-1.4-1.4-1.3-0.3-1.4-0.6-1.3-1.4-1.1-1.01.0
Total zone transitions, hab. session 10.60.81.30.7-0.60.70.7-0.4-0.40.81.01.01.01.11.10.81.01.01.01.11.01.0-1.0
Total locomotion distance, hab. session 10.50.71.00.9-0.70.90.9-0.6-0.60.91.00.90.80.91.00.50.90.70.90.90.80.8-0.6
Locomotion velocity, hab. session 10.30.40.91.0-0.80.80.8-0.7-0.70.80.90.60.50.50.70.10.60.30.50.60.40.4-0.3
Time in familiar zone, hab. session 20.40.40.90.9-0.90.90.9-0.7-0.70.90.90.60.30.50.5-0.00.60.20.60.50.40.4-0.4
Time in novel zone, hab. session 20.20.20.4-0.50.5-0.5-0.50.00.0-0.6-0.6-0.6-0.4-0.5-0.6-0.3-0.6-0.4-0.6-0.6-0.5-0.50.4
Total zone transitions, hab. session 20.20.31.40.6-0.70.60.6-1.2-1.20.60.50.10.20.00.1-0.20.1-0.20.10.1-0.0-0.00.2
Total locomotion distance, hab. session 21.21.62.81.2-1.31.41.4-1.7-1.71.41.31.31.21.21.30.81.30.91.31.21.11.1-0.9
Locomotion velocity, hab. session 21.21.62.31.1-1.21.31.3-1.5-1.51.31.31.41.31.21.30.91.31.01.31.21.21.2-1.0
Novel to familiar place preference ratio0.10.10.50.6-0.50.40.4-0.7-0.70.50.50.00.00.10.1-0.4-0.0-0.20.10.1-0.0-0.1-0.3
Novelty place preference0.10.10.30.3-0.20.20.2-0.5-0.50.20.2-0.2-0.2-0.2-0.1-0.5-0.3-0.4-0.2-0.2-0.3-0.3-0.0
Time in novel zone, NPP test0.10.10.30.1-0.0-0.1-0.1-0.3-0.3-0.1-0.0-0.4-0.4-0.4-0.3-0.5-0.4-0.5-0.4-0.4-0.4-0.50.1
Total zone transitions, NPP test0.91.31.90.7-0.70.90.9-0.7-0.70.91.11.31.41.31.41.21.31.31.31.31.31.3-1.1
Total locomotion distance, NPP test1.21.72.21.4-1.31.51.5-1.3-1.31.51.51.41.31.31.40.71.30.91.31.21.11.1-1.0
Locomotion velocity, NPP test2.02.83.71.7-1.61.81.8-1.5-1.51.91.91.81.81.71.81.01.71.31.81.71.61.5-1.5
Intraocular pressure0.60.81.40.6-0.70.90.9-0.5-0.50.80.61.21.11.11.00.51.11.11.11.11.11.1-0.8
Delta distance traveled before/after self-admin1.41.54.1-0.30.5-0.7-0.70.10.1-0.7-0.7-1.4-1.4-1.4-1.4-2.0-1.5-1.7-1.4-1.4-1.3-1.51.0
Delta ambulatory time before/after self-admin1.01.22.5-0.70.8-1.0-1.00.30.3-1.0-0.9-1.3-1.4-1.3-1.2-1.6-1.3-1.3-1.3-1.2-1.2-1.31.1
Parametrial fat weight0.81.83.2-0.60.6-0.9-0.90.40.4-0.9-1.0-1.7-1.6-1.6-1.6-1.6-1.7-1.8-1.6-1.7-1.8-1.71.1
Pavlov. Cond. lever latency1.51.95.32.0-2.01.61.6-2.3-2.31.51.2-0.4-0.7-0.5-0.5-1.9-0.5-1.6-0.4-0.5-0.9-1.00.5
Pavlov. Cond. magazine entry latency1.51.95.0-1.61.6-1.1-1.12.12.1-1.0-0.80.91.21.01.02.21.11.90.91.01.41.5-0.9
Pavlov. Cond. change in total contacts1.61.74.5-1.91.9-1.8-1.82.12.1-1.8-1.6-0.9-0.5-0.7-0.80.4-0.8-0.0-0.8-0.8-0.5-0.40.7
Pavlov. Cond. index score1.92.46.0-2.02.0-1.5-1.52.42.4-1.4-1.10.81.10.90.92.41.02.00.80.81.31.5-0.8
Pavlov. Cond. latency score1.82.26.2-2.22.2-1.7-1.72.52.5-1.6-1.30.40.80.60.62.20.61.70.50.51.01.2-0.6
Pavlov. Cond. lever contacts1.61.95.8-2.02.1-1.7-1.72.42.4-1.6-1.30.20.50.30.31.70.41.40.20.30.70.9-0.3
Pavlov. Cond. magazine entry number1.62.16.01.1-1.10.60.6-1.7-1.70.50.3-1.3-1.6-1.4-1.4-2.4-1.5-2.2-1.3-1.4-1.7-1.81.2
Pavlov. Cond. intertrial magazine entries1.61.95.12.0-2.12.02.0-2.3-2.31.91.70.80.80.80.8-0.40.7-0.10.80.80.50.3-0.6
Pavlov. Cond. lever-magazine prob. diff.1.92.46.4-1.91.8-1.4-1.42.32.3-1.2-0.90.91.31.11.02.51.12.11.01.01.51.6-0.9
Pavlov. Cond. response bias1.92.46.5-1.71.6-1.2-1.22.22.2-1.0-0.81.11.41.21.12.61.32.21.11.21.61.7-1.1
Pavlov. Cond. lever latency0.40.50.7-0.80.8-0.8-0.80.50.5-0.8-0.7-0.7-0.7-0.7-0.7-0.6-0.8-0.4-0.7-0.7-0.6-0.60.5
Pavlov. Cond. magazine entry latency0.50.61.0-0.81.0-1.0-1.01.01.0-1.0-0.9-0.8-0.7-0.7-0.7-0.3-0.7-0.5-0.8-0.7-0.6-0.60.7
Pavlov. Cond. change in total contacts0.10.10.30.1-0.20.10.1-0.5-0.50.0-0.1-0.5-0.4-0.4-0.4-0.4-0.4-0.6-0.4-0.4-0.5-0.50.3
Pavlov. Cond. index score0.00.10.3-0.20.3-0.2-0.20.50.5-0.2-0.3-0.1-0.1-0.1-0.00.20.0-0.0-0.1-0.0-0.00.00.2
Pavlov. Cond. latency score0.00.00.1-0.00.1-0.2-0.20.30.3-0.2-0.2-0.2-0.2-0.2-0.2-0.1-0.2-0.2-0.2-0.2-0.2-0.20.3
Pavlov. Cond. lever contacts0.20.20.40.6-0.60.60.6-0.4-0.40.60.50.40.50.40.50.40.50.30.50.50.40.4-0.3
Pavlov. Cond. magazine entry number0.30.30.50.4-0.50.50.5-0.6-0.60.60.70.70.60.70.60.40.50.60.70.60.60.6-0.7
Pavlov. Cond. intertrial magazine entries0.81.22.7-0.80.7-0.3-0.31.31.3-0.2-0.11.11.11.21.11.61.11.61.11.11.31.4-1.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.3-0.10.2-0.2-0.20.50.5-0.2-0.2-0.00.0-0.00.00.20.10.0-0.00.10.00.10.1
Pavlov. Cond. response bias0.10.10.4-0.10.10.00.00.30.30.00.00.30.40.40.40.70.50.50.40.40.40.5-0.3
Time in closed arm before self-admin0.10.10.3-0.0-0.10.10.1-0.5-0.50.20.20.10.50.40.30.60.20.20.30.30.10.3-0.5
Time in closed arm after self-admin0.60.61.50.4-0.70.40.4-1.2-1.20.3-0.0-1.0-0.7-0.7-0.8-0.5-0.8-1.0-0.7-0.8-1.0-1.00.4
Time in open arm before self-admin0.20.20.6-0.20.3-0.1-0.10.70.7-0.1-0.10.40.20.50.50.20.60.80.60.50.70.7-0.6
Time in open arm after self-admin0.30.31.6-0.60.8-0.6-0.61.31.3-0.6-0.40.40.20.20.3-0.20.40.60.30.30.30.50.3
Bone: periosteal estimation3.16.611.1-3.23.2-3.3-3.32.52.5-3.3-3.2-2.6-2.5-2.4-2.4-0.9-2.3-1.4-2.4-2.4-2.0-1.92.1
Bone: periosteal perimeter1.72.95.9-2.42.4-2.4-2.42.32.3-2.3-2.2-1.4-1.2-1.2-1.20.0-1.2-0.4-1.3-1.2-0.9-0.81.0
Bone: post-yield work1.21.85.0-2.22.1-1.9-1.92.02.0-1.7-1.8-0.10.10.20.01.50.21.20.10.20.60.7-0.4
Progressive ratio test 1 active lever presses0.40.52.70.9-0.90.80.8-1.2-1.20.70.5-0.0-0.3-0.2-0.1-1.60.1-0.90.0-0.2-0.5-0.30.4
Progressive ratio test 1 breakpoint0.40.52.90.9-0.80.70.7-1.1-1.10.60.5-0.1-0.4-0.2-0.2-1.70.0-0.9-0.0-0.2-0.5-0.30.5
Progressive ratio test 1 inactive lever presses0.81.14.11.6-1.51.31.3-2.0-2.01.31.3-0.0-0.00.00.0-1.1-0.1-0.90.1-0.0-0.2-0.3-0.1
Progressive ratio test 2 active lever presses0.60.72.51.1-1.21.21.2-1.6-1.61.00.70.40.40.40.4-0.70.6-0.20.50.30.10.3-0.0
Progressive ratio test 2 breakpoint0.60.72.71.1-1.21.21.2-1.6-1.61.00.70.40.30.40.4-0.80.6-0.30.50.30.00.20.0
Progressive ratio test 2 inactive lever presses0.20.41.4-0.10.3-0.4-0.4-0.2-0.2-0.4-0.4-0.8-0.8-0.6-0.6-1.2-0.6-1.0-0.6-0.7-0.8-0.60.6
Incentive Sensitization - Responses0.50.71.10.6-0.70.80.8-1.0-1.00.80.60.81.00.90.90.61.00.50.90.80.70.9-0.5
Incentive Sensitization - Breakpoint0.50.71.20.6-0.80.90.9-1.1-1.10.90.60.81.00.90.90.61.00.50.90.80.80.8-0.6
Sum of active levers in priming session hrs 5-60.30.30.80.2-0.20.30.30.20.20.30.20.70.60.60.70.00.90.60.70.60.60.7-0.1
Progressive ratio3.55.510.3-0.70.7-1.2-1.2-0.0-0.0-1.4-1.6-2.9-2.8-2.9-2.8-3.1-2.8-3.2-2.7-2.8-3.0-2.92.9
Food seeking constrained by brief footshock0.10.10.50.3-0.20.30.3-0.1-0.10.30.30.10.50.40.3-0.30.20.10.30.20.10.3-0.7
Seeking ratio, punishment vs. effort3.34.88.10.8-0.81.31.3-0.1-0.11.41.52.62.72.82.72.52.62.82.62.62.72.7-2.9
Retroperitoneal fat weight0.31.52.7-0.50.4-0.7-0.70.40.4-0.8-1.2-1.4-1.7-1.4-1.6-1.4-1.4-1.6-1.4-1.3-1.4-1.51.4
Reaction time number correct0.40.82.41.4-1.51.31.3-1.5-1.51.21.1-0.2-0.2-0.1-0.1-0.6-0.4-0.9-0.1-0.2-0.5-0.60.1
Reaction time mean minus median1.43.510.1-3.23.0-2.6-2.62.82.8-2.6-2.8-0.2-0.2-0.2-0.22.00.11.2-0.2-0.10.40.60.5
Reaction time mean minus median AUC0.92.36.6-2.62.2-1.9-1.92.42.4-1.9-2.30.00.10.10.12.10.41.10.00.10.50.70.4
Reaction time num false alarms0.40.61.3-0.60.7-0.8-0.81.11.1-0.8-0.5-0.9-0.8-0.8-0.7-0.3-0.7-0.5-0.8-0.7-0.7-0.71.0
Reaction time num false alarms AUC0.60.91.5-0.70.9-1.0-1.01.21.2-1.0-0.6-1.1-1.0-1.0-0.9-0.6-0.9-0.7-1.0-0.9-0.9-0.91.1
Reaction time trials correct on left0.40.82.41.4-1.51.31.3-1.5-1.51.21.1-0.2-0.2-0.1-0.1-0.6-0.4-0.9-0.1-0.2-0.5-0.60.1
Reaction time trials on left0.40.72.01.3-1.41.21.2-1.4-1.41.01.0-0.2-0.2-0.2-0.2-0.5-0.4-0.9-0.2-0.2-0.5-0.60.2
Reaction time mean1.93.19.1-2.62.7-2.2-2.23.03.0-2.1-2.00.30.40.40.42.30.61.70.20.40.91.0-0.1
Reaction time mean AUC2.03.29.4-2.72.7-2.3-2.33.13.1-2.2-2.10.20.40.30.42.30.61.70.20.40.91.00.1
Median of all reaction times1.42.06.3-1.92.1-1.7-1.72.52.5-1.6-1.30.30.50.40.51.90.51.50.30.40.80.9-0.2
Reaction time omissions1.31.95.3-2.32.2-1.9-1.92.32.3-1.9-1.90.1-0.00.00.11.20.21.20.10.00.50.70.3
Reaction time false alarm rate0.91.34.1-1.41.7-1.6-1.62.02.0-1.5-1.1-0.8-0.8-0.7-0.6-0.2-0.5-0.1-0.8-0.7-0.5-0.40.9
Reaction time premature initiation rate1.01.42.6-0.30.5-0.7-0.70.40.4-0.7-0.6-1.3-1.6-1.5-1.5-1.6-1.5-1.6-1.5-1.4-1.5-1.51.0
Reaction time premature initiations1.01.74.40.5-0.4-0.0-0.0-0.4-0.4-0.1-0.1-1.4-1.7-1.5-1.6-2.0-1.6-2.1-1.5-1.5-1.8-1.81.1
Std. dev. reaction times2.24.011.0-3.33.2-2.8-2.83.23.2-2.8-2.9-0.3-0.5-0.4-0.31.7-0.01.1-0.4-0.20.30.40.8
Reaction time trials completed0.40.72.01.3-1.41.21.2-1.4-1.41.01.0-0.2-0.2-0.2-0.2-0.5-0.4-0.9-0.2-0.2-0.5-0.60.2
Reaction time trials AUC0.40.82.21.3-1.51.21.2-1.5-1.51.11.0-0.1-0.1-0.1-0.1-0.5-0.3-0.8-0.1-0.1-0.4-0.50.1
Run reversals in cocaine runway, females0.50.51.61.3-0.90.90.9-0.9-0.91.01.20.1-0.00.20.2-1.00.2-0.50.20.1-0.1-0.1-0.3
Run reversals in cocaine runway, males3.23.26.3-2.52.5-2.4-2.42.52.5-2.4-2.3-1.2-1.4-1.4-1.20.2-1.0-0.4-1.3-1.3-1.0-0.81.5
Latency to leave start box in cocaine runway0.10.10.90.1-0.20.20.20.00.00.20.10.40.20.40.30.90.20.60.30.30.40.4-0.5
Latency to leave start box in cocaine runway, F0.50.52.70.1-0.20.30.30.10.10.40.50.80.60.80.81.70.61.20.70.70.80.8-1.0
Latency to leave start box in cocaine runway, M0.50.51.0-0.30.2-0.4-0.40.00.0-0.4-0.8-0.9-0.8-0.8-1.0-0.8-0.9-0.9-0.9-0.9-0.8-0.90.7
Std. dev. time between licks in bursts1.72.37.2-2.42.4-2.1-2.12.72.7-2.0-1.9-0.4-0.3-0.4-0.41.1-0.30.8-0.4-0.40.20.30.1
Total sessions with >9 infusions0.40.52.10.4-0.30.20.2-0.8-0.80.1-0.1-0.6-0.9-0.7-0.6-1.5-0.5-1.1-0.5-0.8-0.9-0.70.8
Short access day 1 total inactive lever presses2.63.44.7-1.92.0-2.2-2.21.41.4-2.2-2.0-2.0-2.0-1.9-1.8-1.1-1.8-1.4-1.9-2.1-1.8-1.61.9
Short access day 10 total inactive lever presses0.10.30.70.10.2-0.0-0.00.30.30.20.80.50.60.60.60.60.30.50.50.60.70.6-0.8
Short access day 1 total infusions0.10.10.40.5-0.40.40.4-0.6-0.60.30.10.2-0.2-0.00.0-0.60.3-0.10.1-0.1-0.2-0.00.3
Short access day 10 total infusions0.30.42.00.6-0.40.30.3-0.9-0.90.30.0-0.6-0.7-0.5-0.5-1.4-0.4-1.0-0.4-0.5-0.7-0.60.5
Short access total infusions0.50.73.50.6-0.40.30.3-1.0-1.00.20.0-0.6-1.1-0.7-0.7-1.9-0.6-1.1-0.6-0.8-1.0-0.90.9
Short access day 1 locomotion1.01.22.30.9-0.91.11.1-0.7-0.71.10.71.31.41.31.30.71.50.91.41.21.21.3-1.0
Short access day 10 total locomotion0.51.02.4-1.41.2-1.3-1.31.31.3-1.2-1.6-1.0-0.5-0.8-0.70.2-0.7-0.3-0.8-0.9-0.7-0.50.8
Short access total locomotion0.10.10.4-0.30.3-0.3-0.30.30.3-0.2-0.6-0.3-0.1-0.1-0.1-0.40.0-0.2-0.1-0.3-0.3-0.00.2
One hour access (0.3 mA shock)1.21.42.31.0-0.91.11.1-0.8-0.81.21.11.41.41.41.4-0.11.50.91.51.21.11.3-1.3
Compulsive drug intake2.63.15.70.2-0.00.50.50.80.80.81.22.32.12.22.31.92.22.42.22.02.32.4-2.3
One hour access (shock baseline)0.30.52.30.3-0.30.10.1-0.8-0.80.0-0.5-0.7-0.7-0.7-0.7-1.5-0.5-1.1-0.6-0.7-0.9-0.80.8
Social response proportion0.30.30.8-0.80.9-0.8-0.80.50.5-0.8-0.8-0.2-0.3-0.4-0.3-0.1-0.4-0.1-0.4-0.4-0.2-0.20.6
Social responses0.20.30.4-0.50.4-0.5-0.5-0.2-0.2-0.5-0.6-0.5-0.6-0.6-0.6-0.5-0.6-0.6-0.6-0.6-0.6-0.60.6
Social time1.92.67.9-2.62.6-2.4-2.42.82.8-2.2-2.1-0.5-0.3-0.4-0.41.1-0.20.8-0.4-0.50.00.20.1
Soleus weight1.64.813.3-3.43.6-3.3-3.33.63.6-3.1-2.8-1.1-0.8-0.8-0.80.8-0.80.5-0.9-0.7-0.3-0.10.3
Bone: stiffness0.50.81.80.1-0.2-0.1-0.1-0.7-0.7-0.2-0.4-1.1-1.1-1.1-1.1-1.2-1.1-1.3-1.1-1.0-1.2-1.30.9
Tibialis anterior weight0.31.03.51.5-1.51.31.3-1.9-1.91.31.3-0.2-0.1-0.1-0.2-0.9-0.3-0.8-0.00.0-0.3-0.5-0.6
Time to tail flick, vehicle, before self-admin0.80.92.7-0.10.10.10.10.80.80.30.20.91.01.11.11.71.11.21.01.01.01.2-1.3
Time to tail flick, vehicle, after self-admin0.40.51.2-0.70.7-0.4-0.40.80.8-0.3-0.30.60.70.80.81.00.91.10.70.50.71.0-0.8
Time to tail flick, test, before self-admin0.10.10.40.1-0.20.20.2-0.4-0.40.20.10.30.10.20.30.30.20.10.30.30.30.2-0.7
Time to tail flick, test, after self-admin0.40.41.4-0.60.4-0.2-0.20.60.6-0.3-0.40.60.60.50.51.20.61.10.50.50.80.7-0.3
Delta time to tail flick, vehicle, before/after SA0.10.10.40.3-0.50.40.4-0.6-0.60.40.30.30.20.20.1-0.50.20.10.20.20.20.10.0
Delta time to tail flick, test, before/after SA0.40.40.70.6-0.70.70.7-0.5-0.50.70.70.70.80.70.60.80.70.70.60.60.60.6-0.1
Tibia length3.18.613.8-3.63.5-3.7-3.72.92.9-3.7-3.5-2.9-2.7-2.7-2.9-1.0-2.7-1.7-2.8-2.8-2.4-2.22.5
Ambulatory time before self-admin0.30.40.8-0.80.9-0.9-0.90.90.9-0.9-0.6-0.2-0.5-0.5-0.4-0.1-0.40.0-0.5-0.6-0.5-0.30.7
Ambulatory time after self-admin1.72.03.0-1.31.7-1.7-1.71.21.2-1.7-1.3-1.2-1.6-1.4-1.4-1.7-1.4-1.1-1.5-1.4-1.2-1.21.3
Bone: tissue strength3.13.15.2-0.60.8-1.2-1.20.40.4-1.2-0.8-2.3-2.2-2.1-2.1-2.3-2.3-2.2-2.1-2.1-2.2-2.31.7
Total heroin consumption0.20.20.6-0.50.7-0.6-0.60.80.8-0.6-0.4-0.1-0.1-0.1-0.1-0.5-0.0-0.0-0.1-0.10.00.10.2
Bone: trabecular number1.72.84.62.0-1.92.02.0-1.7-1.72.12.21.61.71.61.60.71.60.91.61.71.41.3-1.7
Bone: trabecular spacing3.75.06.4-2.12.1-2.4-2.41.61.6-2.4-2.4-2.5-2.5-2.4-2.5-1.6-2.4-1.9-2.4-2.4-2.2-2.22.2
Bone: trabecular thickness1.21.62.31.4-1.41.51.5-0.8-0.81.41.51.41.41.31.30.91.30.91.31.21.11.1-1.0
Bone: trabecular tissue density1.31.93.9-0.70.5-0.8-0.80.50.5-1.0-1.2-1.5-1.5-1.7-1.7-1.3-1.5-1.6-1.6-1.7-1.7-1.62.0
Water consumed over 24 hours0.00.10.2-0.30.4-0.4-0.40.50.5-0.3-0.3-0.20.0-0.0-0.00.2-0.10.1-0.1-0.0-0.00.0-0.3
Number of responses in last shaping day0.50.61.1-0.50.6-0.7-0.70.20.2-0.7-0.6-0.8-1.0-0.8-0.8-0.9-0.7-0.7-0.8-0.9-0.9-0.71.0