Hub : Genes

H2-Q7-ps1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr20_2631404_2662623 0.2 0.12 1.0e-06 0.03 0.03 0.02 0.02 2.8e-04 2.3e-04 1.4e-03 9.5e-04
2 Adipose intron excision ratio chr20_2675633_2675825 0.27 0.14 3.6e-09 0.06 0.06 0.05 0.06 6.5e-07 3.3e-07 1.1e-06 9.3e-07
3 Adipose intron excision ratio chr20_2629035_2629238 0.35 0.14 6.9e-14 0.01 0.05 0.04 0.04 2.5e-02 3.8e-06 2.8e-05 4.6e-05
4 Adipose intron excision ratio chr20_2637860_2638063 0.35 0.14 6.9e-14 0.01 0.05 0.04 0.04 2.5e-02 3.8e-06 2.8e-05 4.7e-05
5 Adipose intron excision ratio chr20_2622575_2622726 0.05 0.04 3.1e-03 0.02 0 -0 0.01 5.8e-03 1.2e-01 5.2e-01 5.0e-02
6 Adipose intron excision ratio chr20_2622575_2631555 0.05 0.04 3.5e-03 0.02 0 -0 0.01 5.8e-03 1.1e-01 5.4e-01 5.4e-02
7 Eye intron excision ratio chr20_2631404_2662623 0.76 0.14 7.8e-06 0.05 0.19 0.07 0.14 5.9e-02 7.7e-04 2.7e-02 3.2e-03
8 Adipose intron excision ratio chr20_2631404_2640514 0.23 0.12 1.8e-08 0.02 0.04 0.04 0.04 1.3e-03 2.7e-05 1.5e-05 1.3e-05
9 IL gene expression H2-Q7-ps1 0.61 0.14 1.6e-14 0.4 0.42 0.41 0.42 9.5e-11 3.9e-11 5.0e-11 1.9e-11
10 Liver gene expression H2-Q7-ps1 0.52 0.09 0.0e+00 0.59 0.58 0.59 0.6 1.2e-81 9.7e-79 5.7e-81 2.8e-84
11 Adipose gene expression H2-Q7-ps1 0.39 0.11 0.0e+00 0.48 0.47 0.49 0.48 3.3e-59 4.6e-59 4.3e-62 9.3e-61
12 NAcc gene expression H2-Q7-ps1 0.29 0.09 0.0e+00 0.35 0.36 0.37 0.37 4.5e-55 2.4e-57 1.5e-58 1.3e-58
13 Eye gene expression H2-Q7-ps1 0.33 0.19 3.5e-03 0.04 0.06 0.05 0.07 7.8e-02 4.2e-02 6.9e-02 2.9e-02
14 PL gene expression H2-Q7-ps1 0.48 0.11 0.0e+00 0.56 0.56 0.56 0.56 2.6e-74 7.5e-73 9.6e-75 1.1e-73
15 LHb gene expression H2-Q7-ps1 0.47 0.24 1.2e-07 0.22 0.25 0.26 0.23 6.4e-06 9.7e-07 8.3e-07 3.0e-06
16 BLA gene expression H2-Q7-ps1 0.68 0.14 0.0e+00 0.5 0.52 0.52 0.52 2.4e-30 5.3e-32 1.8e-31 1.8e-31
17 OFC gene expression H2-Q7-ps1 0.61 0.14 1.7e-14 0.35 0.35 0.4 0.41 3.2e-09 4.7e-09 1.2e-10 8.3e-11
18 Brain gene expression H2-Q7-ps1 0.33 0.13 0.0e+00 0.31 0.31 0.32 0.32 1.7e-29 1.1e-29 1.2e-30 3.4e-30
19 IC gene expression H2-Q7-ps1 0.57 0.1 0.0e+00 0.3 0.41 0.39 0.35 5.2e-13 2.1e-18 1.4e-17 1.3e-15
20 NAcc intron excision ratio chr20_2631404_2662623 0.02 0.02 5.0e-03 0.01 0 0 0 3.7e-02 2.1e-01 3.3e-01 3.4e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Bone: apparent density1.42.64.01.7-1.71.81.81.41.41.92.01.61.7-1.71.70.9-1.6-1.01.61.7-1.51.41.7
Area under the delay curve1.01.52.7-0.50.3-0.6-0.60.10.1-0.8-1.1-1.5-1.61.5-1.6-1.01.31.5-1.5-1.51.6-1.6-1.6
BMI with tail0.82.96.20.8-1.00.40.41.61.60.20.0-1.9-1.91.9-1.9-2.42.02.5-1.7-1.92.1-2.2-1.8
BMI without tail1.26.312.4-0.20.1-0.8-0.80.90.9-0.9-1.2-3.0-3.43.1-3.1-3.53.23.5-2.9-3.03.2-3.4-2.6
Body weight5.624.635.9-3.63.5-4.4-4.4-2.1-2.1-4.6-4.6-5.9-6.05.9-5.9-4.45.95.2-5.8-5.75.5-5.6-5.4
Weight adjusted by age1.23.64.8-1.81.8-2.1-2.1-1.5-1.5-2.1-1.9-2.0-2.02.2-2.0-0.71.91.6-2.2-2.22.0-1.9-2.1
Bone surface0.20.40.9-0.91.0-0.9-0.9-0.6-0.6-0.8-0.8-0.6-0.50.4-0.4-0.00.50.2-0.5-0.30.3-0.30.1
Bone volume0.00.00.20.1-0.0-0.0-0.00.00.00.00.1-0.3-0.30.2-0.2-0.30.30.4-0.2-0.10.3-0.30.0
Breakpoint value in progressive ratio session0.10.20.60.2-0.10.30.30.00.00.30.30.70.6-0.60.7-0.3-0.8-0.70.70.6-0.70.70.3
Number of licking bursts0.10.41.1-0.90.9-0.7-0.7-1.1-1.1-0.6-0.60.30.4-0.40.40.9-0.4-0.80.40.4-0.60.60.5
Context. condit. distance diff. score4.35.211.5-0.81.0-0.3-0.3-1.9-1.9-0.00.32.42.5-2.62.63.4-2.6-3.42.52.7-3.03.02.8
Locomotion velocity, session 10.20.30.8-0.50.5-0.3-0.3-0.5-0.5-0.3-0.00.30.5-0.50.50.9-0.4-0.80.40.4-0.60.60.4
Locomotion distance, session 10.81.12.61.4-1.41.41.41.61.61.31.50.80.8-0.70.90.0-0.7-0.20.80.7-0.50.50.4
Locomotion velocity, session 20.00.10.2-0.50.4-0.4-0.4-0.3-0.3-0.4-0.1-0.0-0.00.0-0.00.3-0.0-0.2-0.0-0.1-0.00.1-0.3
Locomotion distance, session 20.30.40.80.6-0.70.70.70.80.80.70.90.70.7-0.60.70.5-0.7-0.50.70.5-0.50.60.2
Locomotion velocity, session 30.20.30.90.9-0.70.60.60.90.90.60.8-0.00.00.00.0-0.50.10.4-0.0-0.10.2-0.3-0.0
Locomotion distance, session 31.21.42.00.9-0.81.01.00.60.61.11.31.41.2-1.41.40.9-1.3-1.21.41.4-1.31.31.4
Stereotopy head waving bouts, day 32.22.64.0-1.81.9-2.0-2.0-1.5-1.5-2.0-1.8-1.6-1.61.6-1.6-0.71.51.0-1.6-1.61.4-1.2-1.6
Stereotopy head waving duration, day 31.41.72.3-1.41.4-1.5-1.5-1.0-1.0-1.5-1.4-1.4-1.41.4-1.4-0.71.30.9-1.3-1.41.2-1.1-1.5
Locomotion velocity, session 73.64.06.20.9-0.91.31.30.50.51.51.52.42.4-2.42.42.3-2.4-2.42.42.5-2.52.42.4
Locomotion distance, session 73.54.56.81.5-1.51.91.91.01.02.02.02.52.4-2.52.42.0-2.4-2.12.42.5-2.42.32.6
Stereotopy head waving bouts, day 72.63.04.5-1.11.3-1.5-1.5-0.8-0.8-1.6-1.3-2.0-2.12.1-2.0-1.62.01.8-2.0-2.12.0-1.9-2.1
Stereotopy head waving duration, day 72.53.14.7-1.21.3-1.6-1.6-0.8-0.8-1.6-1.5-2.1-2.22.1-2.0-1.62.01.8-2.1-2.12.1-1.9-2.1
Locomotion velocity, session 82.32.88.2-2.72.7-2.4-2.4-2.9-2.9-2.3-1.9-0.3-0.30.3-0.21.40.1-1.1-0.3-0.3-0.20.5-0.5
Locomotion distance, session 82.23.27.4-0.50.7-0.1-0.1-1.3-1.30.10.52.02.1-2.12.12.7-2.1-2.72.02.1-2.42.42.0
Degree of sensitization distance0.40.41.2-0.70.6-0.4-0.4-0.9-0.9-0.4-0.50.40.6-0.50.41.1-0.5-0.90.40.5-0.60.70.6
Degree of sensitization stereotypy1.01.11.8-0.40.6-0.8-0.8-0.1-0.1-0.8-0.6-1.2-1.31.3-1.2-1.11.21.2-1.3-1.31.3-1.2-1.3
Conditioned locomotion0.81.02.0-1.10.9-1.0-1.0-0.4-0.4-1.1-1.4-1.0-1.01.1-1.1-0.50.90.7-1.0-1.11.0-0.8-1.4
Cocaine response after cond. corrected0.40.60.90.7-0.60.70.70.50.50.80.90.90.9-0.90.90.6-0.9-0.70.91.0-0.90.80.7
Cocaine response after cond. not corrected0.20.30.9-0.90.9-0.9-0.9-0.7-0.7-0.9-0.8-0.4-0.30.3-0.40.10.3-0.1-0.4-0.30.2-0.1-0.5
Cocaine response before conditioning5.76.99.6-2.82.6-2.9-2.9-1.9-1.9-3.0-3.1-2.9-2.82.8-2.8-1.62.81.9-2.8-2.92.5-2.4-2.6
Saline control response1.11.63.70.7-0.80.40.41.41.40.30.0-1.3-1.31.3-1.4-1.91.41.9-1.2-1.31.6-1.7-1.0
Bone: connectivity density2.13.34.81.2-1.11.41.40.80.81.61.72.12.2-2.22.11.8-2.1-1.92.12.2-2.12.02.2
Bone: cortical apparent density0.40.71.81.4-1.31.11.10.90.90.90.9-0.2-0.30.3-0.4-1.00.31.0-0.3-0.30.6-0.7-0.6
Bone: cortical area1.32.23.3-0.91.0-1.3-1.3-0.7-0.7-1.3-1.1-1.8-1.81.8-1.7-1.41.71.6-1.8-1.71.7-1.7-1.6
Bone: cortical porosity0.40.51.0-0.30.2-0.3-0.30.10.1-0.4-0.2-0.9-1.00.9-0.8-0.80.90.9-0.8-0.90.9-0.9-0.8
Bone: cortical porosity0.60.61.0-0.90.8-0.9-0.9-0.2-0.2-0.9-0.8-0.9-1.00.9-0.8-0.40.90.6-0.8-0.90.8-0.8-0.8
Bone: cortical thickness2.03.38.01.2-1.10.50.51.31.30.30.4-1.9-2.02.0-1.9-2.82.02.8-2.0-2.02.4-2.5-2.0
Bone: cortical thickness1.21.43.91.7-1.71.31.32.02.01.10.9-0.5-0.60.6-0.6-1.50.71.3-0.6-0.71.0-1.1-0.7
Bone: cortical tissue density0.30.51.61.3-1.21.01.00.90.90.90.8-0.1-0.30.3-0.3-0.90.20.8-0.3-0.20.5-0.6-0.5
Condit. Reinf. active minus inactive responses0.60.71.30.4-0.40.60.60.10.10.60.51.01.1-1.01.00.9-1.0-1.01.01.0-1.01.00.7
Condit. Reinf. active-inactive response ratio0.10.10.40.5-0.60.50.50.40.40.40.20.10.1-0.0-0.1-0.3-0.00.3-0.0-0.00.1-0.1-0.2
Condit. Reinf. active responses1.11.42.40.7-0.81.01.00.40.41.01.01.41.6-1.41.41.2-1.3-1.31.31.4-1.31.31.2
Condit. Reinf. inactive responses2.22.94.01.6-1.61.81.81.31.31.82.01.81.9-1.81.91.2-1.7-1.41.81.8-1.71.61.8
Incentive salience index mean1.01.33.2-0.50.4-0.1-0.1-0.9-0.9-0.0-0.01.21.5-1.31.31.8-1.3-1.71.21.3-1.41.51.1
Condit. Reinf. lever presses1.92.97.3-1.01.1-0.5-0.5-1.7-1.7-0.3-0.11.71.9-1.81.82.7-1.8-2.51.71.8-2.12.21.7
Condit. Reinf. active minus inactive responses0.91.42.0-1.10.9-1.1-1.1-0.4-0.4-1.2-1.3-1.4-1.41.4-1.4-0.61.31.0-1.3-1.41.3-1.2-1.4
Condit. Reinf. active-inactive response ratio1.93.14.4-1.81.6-1.8-1.8-1.0-1.0-1.9-2.1-2.0-1.91.9-2.0-1.01.91.4-1.9-2.01.7-1.6-2.0
Condit. Reinf. active responses0.00.00.2-0.30.1-0.1-0.10.00.0-0.1-0.2-0.00.1-0.10.00.5-0.1-0.30.10.0-0.10.10.2
Condit. Reinf. inactive responses1.31.93.11.0-1.01.21.20.50.51.31.41.61.6-1.61.61.3-1.6-1.41.61.7-1.61.51.7
Condit. Reinf. lever presses0.50.71.40.3-0.30.50.5-0.0-0.00.50.60.90.9-1.01.11.2-1.0-1.01.01.0-1.11.11.1
Condit. Reinf. lever reinforcers received0.00.10.4-0.30.2-0.1-0.1-0.2-0.2-0.1-0.10.10.2-0.20.20.6-0.2-0.40.20.2-0.30.30.3
Conditioned reinforcement - actives0.31.23.40.3-0.2-0.1-0.10.80.8-0.1-0.3-1.2-1.21.2-1.1-1.81.11.7-1.1-1.41.5-1.3-1.3
Conditioned reinforcement - inactives0.51.22.90.4-0.50.10.11.21.20.10.1-1.2-1.41.3-1.2-1.41.21.7-1.1-1.31.4-1.4-1.4
Conditioned locomotion0.20.30.7-0.50.3-0.5-0.5-0.2-0.2-0.4-0.8-0.7-0.40.6-0.6-0.70.50.5-0.6-0.80.7-0.5-0.7
Patch foraging indifference point 0 sec0.41.02.71.6-1.31.11.11.71.71.11.4-0.2-0.60.4-0.2-1.40.41.0-0.2-0.20.6-0.7-0.3
Patch foraging indifference point AUC0.61.42.7-0.90.8-1.0-1.0-0.4-0.4-1.1-1.1-1.6-1.31.4-1.6-0.81.61.2-1.5-1.41.3-1.4-0.9
Delay disc. indifference point, 0s delay0.60.71.4-0.90.8-0.9-0.9-0.7-0.7-1.0-1.2-0.8-1.00.8-0.9-0.50.70.5-0.8-0.80.8-0.7-0.9
Delay disc. indifference point, 16s delay1.21.73.61.1-1.20.80.81.81.80.60.4-1.2-1.31.2-1.3-1.71.11.9-1.2-1.21.5-1.6-1.2
Delay disc. indifference point, 2s delay1.71.92.9-1.11.1-1.3-1.3-0.7-0.7-1.4-1.6-1.4-1.61.6-1.6-1.21.51.3-1.5-1.61.5-1.4-1.7
Delay disc. indifference point, 24s delay0.20.30.90.4-0.50.30.30.80.80.20.0-0.6-0.60.6-0.6-1.00.50.8-0.5-0.50.7-0.7-0.5
Delay disc. indifference point, 4s delay3.23.45.6-1.61.4-1.7-1.7-1.0-1.0-1.9-2.2-2.1-2.12.1-2.1-1.11.91.8-2.1-2.12.0-1.9-2.4
Delay disc. indifference point, 8s delay0.10.20.5-0.1-0.0-0.1-0.10.10.1-0.2-0.3-0.5-0.70.6-0.7-0.00.40.6-0.6-0.60.7-0.7-0.7
Indifference point function ln k0.10.30.9-0.40.5-0.3-0.3-0.7-0.7-0.20.10.50.4-0.50.70.8-0.6-0.90.50.4-0.50.70.3
Indifference point function log k0.10.30.9-0.40.5-0.3-0.3-0.7-0.7-0.20.10.50.4-0.50.70.8-0.6-0.90.50.4-0.50.70.3
Patch foraging total patch changes 0 sec0.41.23.11.7-1.41.11.11.81.81.11.5-0.4-0.80.5-0.4-1.70.61.3-0.4-0.30.8-1.0-0.4
Patch foraging total patch changes 12 sec0.81.13.01.3-1.31.01.01.71.70.90.7-0.7-0.80.7-0.7-1.40.91.3-0.6-0.60.9-1.1-0.5
Patch foraging total patch changes 18 sec0.81.95.82.4-2.21.91.92.22.21.92.30.1-0.0-0.20.2-1.10.10.80.20.30.1-0.40.4
Patch foraging total patch changes 24 sec0.93.17.62.7-2.72.62.62.72.72.52.41.10.7-0.90.9-0.5-0.80.21.01.1-0.60.30.9
Patch foraging total patch changes 6 sec1.01.75.71.9-1.91.61.62.42.41.51.3-0.3-0.60.4-0.5-1.40.51.4-0.3-0.30.7-0.9-0.3
Patch foraging time to switch 0 sec0.31.02.21.5-1.51.41.41.31.31.41.10.80.6-0.70.6-0.1-0.7-0.20.70.7-0.50.40.3
Patch foraging water rate 0 sec0.20.61.1-0.20.0-0.3-0.30.30.3-0.4-0.2-0.9-0.91.0-0.9-0.71.01.0-0.9-1.01.0-1.0-1.0
Patch foraging water rate 12 sec0.10.31.00.9-1.00.90.90.80.80.90.80.20.4-0.10.20.1-0.10.40.20.00.1-0.0-0.2
Patch foraging water rate 18 sec0.20.40.6-0.70.6-0.7-0.70.30.3-0.7-0.5-0.7-0.70.7-0.60.00.60.6-0.6-0.60.6-0.6-0.8
Patch foraging water rate 24 sec1.11.52.9-0.40.4-0.7-0.70.30.3-0.7-0.4-1.7-1.51.6-1.5-1.01.71.5-1.6-1.61.7-1.6-1.4
Patch foraging water rate 6 sec0.20.30.90.7-0.90.70.70.90.90.70.8-0.1-0.10.0-0.0-0.00.10.5-0.0-0.10.2-0.30.1
Seeking ratio, delayed vs. immediate footshock0.40.50.9-0.70.6-0.7-0.7-0.4-0.4-0.8-0.9-0.8-0.80.8-0.8-0.50.70.7-0.8-0.80.8-0.7-1.0
Distance traveled before self-admin0.40.82.2-1.31.4-1.3-1.3-1.5-1.5-1.3-1.0-0.3-0.40.5-0.40.00.4-0.2-0.5-0.60.4-0.1-0.6
Distance traveled after self-admin1.01.83.0-1.41.7-1.7-1.7-1.5-1.5-1.6-1.4-1.1-1.21.2-1.2-1.21.20.9-1.3-1.31.0-1.0-1.0
Extensor digitorum longus weight0.10.51.5-1.11.2-1.1-1.1-1.2-1.2-0.9-0.8-0.4-0.20.1-0.20.30.2-0.3-0.10.0-0.10.00.5
Bone: elastic displacement0.30.40.90.7-0.80.60.60.90.90.50.3-0.3-0.40.4-0.3-0.90.40.9-0.3-0.40.5-0.6-0.5
Bone: elastic work1.41.93.9-0.20.2-0.6-0.60.20.2-0.7-0.5-1.7-1.71.7-1.6-1.81.72.0-1.7-1.71.8-1.8-1.7
Bone: endosteal estimation3.68.919.8-4.44.3-4.3-4.3-3.5-3.5-4.2-4.1-2.5-2.32.2-2.2-0.02.10.6-2.2-2.21.6-1.4-1.8
Bone: endosteal perimeter1.63.811.6-3.43.3-2.9-2.9-3.0-3.0-2.7-2.6-0.5-0.40.2-0.31.60.2-1.2-0.3-0.2-0.40.50.0
Epididymis fat weight2.713.539.55.6-5.84.84.86.36.34.43.9-0.6-1.20.9-1.1-4.21.13.5-0.7-0.71.9-2.3-1.3
Delta time in closed arm before/after self-admin0.20.20.5-0.1-0.0-0.1-0.10.20.2-0.2-0.4-0.6-0.70.6-0.6-0.40.50.6-0.6-0.60.6-0.7-0.5
Delta time in open arm before/after self-admin0.40.41.2-0.50.6-0.6-0.6-0.4-0.4-0.7-0.5-0.5-0.50.7-0.6-0.70.60.5-0.6-0.80.8-0.5-1.1
Diff in mean of infusions in LGA sessions2.74.97.12.0-1.92.32.31.41.42.32.22.72.4-2.52.51.0-2.6-2.12.62.4-2.32.42.1
Delay discount exponential model param1.11.52.80.5-0.30.60.6-0.1-0.10.81.11.51.6-1.61.61.0-1.4-1.51.51.5-1.61.61.7
Extinction: sum of active levers before priming0.40.61.40.5-0.30.60.60.60.60.60.81.20.6-0.90.90.1-0.9-0.60.91.0-0.90.90.7
Active lever presses in extinction session 60.60.61.61.1-1.21.11.11.31.31.10.90.50.4-0.50.4-0.4-0.50.00.50.6-0.30.20.6
Bone: final force3.55.810.9-0.40.4-1.0-1.00.40.4-1.2-1.2-3.0-3.13.0-3.0-3.13.03.3-2.9-2.93.2-3.2-2.6
Bone: final moment3.25.29.4-0.50.5-1.1-1.10.20.2-1.2-1.2-2.9-2.92.8-2.8-2.92.83.1-2.8-2.73.0-3.0-2.5
Food consumed during 24 hour testing period0.81.62.8-1.71.6-1.7-1.7-1.6-1.6-1.6-1.6-1.2-1.01.1-1.0-0.11.00.5-1.1-1.10.9-0.8-1.0
Glucose2.23.58.9-2.82.8-2.3-2.3-3.0-3.0-2.2-1.90.40.6-0.60.62.5-0.7-2.10.50.6-1.21.40.4
Heart weight1.32.04.6-0.50.6-0.9-0.90.00.0-0.9-1.0-1.8-1.51.7-1.8-2.11.91.7-1.7-1.71.7-1.8-1.3
Delay discount hyperbolic model param1.31.63.00.5-0.30.70.7-0.1-0.10.81.11.51.7-1.61.71.0-1.4-1.61.61.6-1.71.61.7
Intermittent access intake day 1-15 change0.00.10.3-0.30.1-0.1-0.1-0.2-0.2-0.1-0.40.10.6-0.20.20.5-0.0-0.20.1-0.0-0.10.20.2
Intermittent access intake escalation0.00.10.2-0.1-0.1-0.0-0.00.20.2-0.0-0.4-0.30.20.2-0.20.00.40.3-0.3-0.40.3-0.3-0.2
Intermittent access intake escalation 20.40.72.0-1.41.3-1.2-1.2-1.3-1.3-1.1-1.3-0.40.20.2-0.21.10.4-0.4-0.4-0.30.0-0.00.0
Intermitt. access day 1 inactive lever presses0.11.02.6-1.41.5-1.5-1.5-1.6-1.6-1.3-0.9-0.7-0.50.8-0.60.40.80.3-0.8-0.80.4-0.5-0.6
Intermitt. access day 15 inactive lever presses0.31.42.9-0.91.0-1.2-1.2-0.9-0.9-1.1-0.6-1.7-1.21.3-1.3-0.61.61.2-1.3-1.31.2-1.3-0.9
Intermitt. access escalation Index0.82.64.90.5-0.61.01.00.20.21.00.92.11.9-2.02.01.9-2.2-1.92.12.1-2.02.11.8
Intermittent access day 1 total infusions0.30.92.81.4-1.21.21.21.61.61.11.10.50.1-0.40.4-1.7-0.60.20.60.6-0.20.30.1
Intermittent access day 15 total infusions0.20.42.00.7-0.80.70.71.21.20.50.1-0.1-0.10.1-0.2-1.4-0.00.7-0.0-0.20.4-0.2-0.4
Intermittent access terminal intake (last 3 days)0.40.63.10.8-0.80.60.61.31.30.50.1-0.5-0.50.5-0.5-1.80.41.1-0.4-0.50.7-0.6-0.7
Intermittent access total infusions0.40.42.80.7-0.60.50.51.11.10.40.1-0.3-0.40.3-0.4-1.70.20.8-0.2-0.20.6-0.4-0.5
Intermittent access day 1 locomotion0.10.11.10.2-0.20.30.30.20.20.2-0.20.20.0-0.20.1-1.1-0.5-0.00.30.2-0.10.3-0.1
Intermittent access day 15 total locomotion0.62.23.9-1.31.1-1.3-1.3-0.7-0.7-1.4-2.0-1.8-1.41.6-1.6-1.51.41.5-1.6-1.71.6-1.4-1.7
Intermittent access total locomotion1.41.62.9-1.00.8-1.0-1.0-0.6-0.6-1.1-1.7-1.5-1.31.4-1.4-1.71.21.4-1.3-1.51.4-1.3-1.6
Intermittent access standard deviation0.42.04.60.1-0.0-0.4-0.40.40.4-0.4-0.6-1.9-1.41.7-1.7-2.11.92.0-1.7-1.71.9-1.9-1.6
Left kidney weight2.117.126.1-2.32.2-3.1-3.1-1.0-1.0-3.3-3.5-5.0-4.95.0-5.0-4.45.14.6-4.9-5.15.1-4.9-4.6
Right kidney weight2.819.628.4-2.92.8-3.6-3.6-1.8-1.8-3.8-4.2-5.3-5.25.3-5.3-4.25.24.8-5.2-5.35.2-5.1-4.8
Cocaine induced anxiety0.30.83.0-0.70.7-0.5-0.5-1.7-1.7-0.4-0.20.90.7-0.60.71.1-0.8-1.20.70.6-0.90.90.7
Post-drug Anxiety0.50.61.4-0.10.10.10.1-1.1-1.10.10.40.90.7-0.80.71.0-0.7-1.20.80.9-0.90.80.9
Baseline Anxiety0.91.53.81.6-1.71.61.61.91.91.61.50.80.8-0.90.80.4-0.7-0.40.91.0-0.70.60.9
Tail length3.920.930.4-5.05.1-5.5-5.5-4.2-4.2-5.5-5.4-4.6-4.74.7-4.6-2.34.63.1-4.7-4.54.0-3.9-4.0
Length with tail7.332.547.3-6.36.4-6.8-6.8-5.1-5.1-6.9-6.7-5.8-5.85.8-5.7-2.85.73.9-5.8-5.65.0-4.9-5.1
Length without tail3.518.423.4-4.24.3-4.7-4.7-3.1-3.1-4.8-4.6-4.8-4.54.7-4.6-2.64.63.4-4.7-4.64.2-4.1-4.4
Times rat made contact with spout2.32.64.62.1-2.12.12.11.81.82.12.01.41.4-1.41.50.2-1.3-0.51.41.4-1.10.91.6
Lifetime Intake0.50.63.80.5-0.40.30.30.90.90.2-0.1-0.5-0.80.6-0.6-1.90.41.1-0.5-0.60.9-0.7-0.8
Liver weight, left2.54.310.3-3.13.1-2.9-2.9-3.2-3.2-2.9-2.9-1.2-1.11.1-1.10.50.90.0-1.1-1.20.7-0.4-1.2
Liver weight, right4.47.714.9-3.73.7-3.7-3.7-3.3-3.3-3.7-3.9-2.4-2.42.4-2.4-0.72.21.1-2.3-2.31.8-1.6-2.1
Locomotor activity2.53.910.4-3.23.0-3.0-3.0-2.4-2.4-2.8-2.7-1.4-1.31.2-1.21.11.3-0.1-1.3-1.20.7-0.7-1.0
Locomotor testing distance0.40.92.8-1.71.6-1.5-1.5-1.2-1.2-1.4-1.2-0.5-0.50.3-0.31.20.4-0.4-0.4-0.20.0-0.1-0.0
Locomotor testing rearing0.31.23.0-1.71.6-1.6-1.6-1.1-1.1-1.6-1.5-0.9-0.90.8-0.80.20.80.0-0.8-0.90.6-0.5-0.8
Locomotion in novel chamber0.60.81.8-0.50.6-0.8-0.8-0.2-0.2-0.7-0.5-1.4-1.01.0-1.0-0.91.01.0-1.0-0.91.2-1.0-0.5
Locomotion in novel chamber post-restriction0.30.82.0-0.0-0.0-0.3-0.30.20.2-0.3-0.5-1.1-1.11.1-1.1-0.61.11.4-1.1-1.01.3-1.2-1.3
Fecal boli incidents, locomotor time 10.30.81.40.8-0.40.70.70.40.40.81.10.91.1-1.11.2-0.1-1.1-0.61.11.0-1.01.01.1
Change in fecal boli incidents, locomotor task0.70.81.3-0.80.6-0.8-0.8-0.7-0.7-0.9-1.0-0.9-0.81.0-1.1-0.61.10.6-1.1-0.80.8-1.0-1.1
Time >=10cm from walls, locomotor time 11.01.32.5-1.51.6-1.6-1.6-1.4-1.4-1.5-1.5-0.9-0.80.9-0.8-0.40.80.6-0.9-0.90.6-0.6-0.9
Bouts of movement, locomotor time 10.50.72.8-0.50.4-0.2-0.2-0.8-0.8-0.2-0.10.51.1-0.90.91.7-1.0-1.30.90.8-0.81.00.9
Total resting periods, locomotor time 10.40.41.2-0.70.7-0.5-0.5-0.9-0.9-0.4-0.40.20.7-0.50.51.1-0.6-0.90.50.5-0.50.70.4
Rest time, locomotor task time 10.60.93.0-1.41.3-1.3-1.3-1.7-1.7-1.3-1.4-0.5-0.20.5-0.50.20.3-0.1-0.5-0.40.2-0.2-0.6
Distance moved, locomotor task time 10.20.41.40.5-0.40.20.20.90.90.20.2-0.5-0.70.6-0.6-1.00.81.2-0.6-0.80.8-0.8-0.4
Vertical activity count, locomotor time 10.00.20.80.4-0.40.20.20.90.90.20.3-0.3-0.60.4-0.5-0.20.60.7-0.4-0.50.5-0.6-0.3
Time >=10cm from walls, locomotor time 20.10.31.1-0.90.8-0.7-0.7-0.9-0.9-0.8-1.1-0.1-0.20.2-0.3-0.00.0-0.2-0.2-0.10.00.0-0.4
Bouts of movement, locomotor time 20.61.94.9-2.21.8-1.9-1.9-2.1-2.1-1.9-2.0-1.0-0.80.8-0.90.90.6-0.1-0.8-0.80.6-0.4-1.2
Total resting periods, locomotor time 20.62.36.1-2.52.1-2.0-2.0-2.4-2.4-2.0-2.2-0.9-0.70.7-0.71.30.4-0.4-0.7-0.60.4-0.2-1.0
Rest time, locomotor task time 21.42.48.7-2.32.3-2.0-2.0-2.9-2.9-1.8-1.8-0.20.4-0.20.21.7-0.4-1.30.00.1-0.40.70.1
Distance moved, locomotor task time 21.01.33.61.3-1.41.01.01.91.90.90.5-0.4-0.80.8-0.8-1.60.91.5-0.7-0.71.0-1.1-0.7
Vertical activity count, locomotor time 20.20.41.30.9-1.10.90.91.21.20.80.60.3-0.10.1-0.2-0.00.20.4-0.00.10.0-0.3-0.0
Light reinforcement 10.10.31.10.9-0.80.70.71.01.00.60.70.1-0.20.1-0.1-0.80.10.3-0.10.10.1-0.3-0.2
Light reinforcement 20.51.22.2-1.21.1-1.2-1.2-1.1-1.1-1.4-1.5-0.9-1.11.2-1.2-0.61.00.5-1.2-1.00.9-0.9-1.4
Bone: marrow area3.68.719.3-4.44.3-4.2-4.2-3.4-3.4-4.1-4.1-2.5-2.32.2-2.2-0.02.10.6-2.2-2.11.6-1.4-1.8
Bone: maximum diameter1.22.46.6-2.52.6-2.4-2.4-2.0-2.0-2.3-2.0-1.0-0.90.8-0.80.40.8-0.1-0.8-0.80.4-0.3-0.5
Bone: maximum force2.75.49.1-0.90.8-1.4-1.40.00.0-1.5-1.6-2.9-2.92.8-2.9-2.72.83.0-2.8-2.83.0-3.0-2.5
Bone: maximum moment2.64.98.0-1.11.0-1.5-1.5-0.3-0.3-1.6-1.6-2.8-2.82.7-2.7-2.52.72.8-2.7-2.62.8-2.8-2.4
Mean time between licks in bursts0.42.48.2-2.42.4-2.1-2.1-2.9-2.9-2.0-1.8-0.1-0.00.00.01.4-0.1-1.1-0.10.0-0.50.6-0.0
Mean num. licks in bursts0.51.33.61.8-1.81.61.61.91.91.61.50.40.4-0.40.3-0.7-0.20.40.40.40.1-0.10.3
Cd content in liver0.50.62.30.8-1.21.11.11.51.51.00.50.50.1-0.20.2-0.2-0.50.10.40.2-0.10.2-0.4
Co content in liver0.91.03.01.0-1.30.90.91.71.70.80.7-0.5-0.70.7-0.6-1.30.61.3-0.5-0.70.9-1.0-0.8
Cu content in liver3.33.96.42.4-2.52.52.52.32.32.52.41.91.7-1.81.80.8-1.7-0.91.81.8-1.51.41.9
Fe content in liver0.60.71.90.6-0.90.60.61.41.40.40.2-0.7-0.60.7-0.8-1.10.81.1-0.6-0.70.9-1.0-0.7
K content in liver0.40.31.50.9-0.60.60.60.00.00.71.20.40.5-0.50.60.4-0.3-0.20.40.5-0.40.31.1
Mg content in liver0.70.82.2-0.30.4-0.1-0.1-0.8-0.80.00.20.91.0-1.01.01.4-0.9-1.30.91.1-1.21.11.5
Mn content in liver2.22.46.2-1.61.7-1.2-1.2-2.1-2.1-1.0-0.61.11.4-1.31.32.5-1.2-2.21.21.3-1.71.71.6
Na content in liver0.50.51.51.0-1.10.90.91.21.20.80.7-0.4-0.20.3-0.3-0.80.51.0-0.3-0.30.5-0.7-0.0
Rb content in liver1.11.23.20.6-0.81.01.00.90.91.00.91.11.1-1.31.11.1-1.1-1.11.31.3-1.31.11.8
Se content in liver1.31.54.2-2.11.8-1.5-1.5-1.9-1.9-1.5-1.70.20.4-0.30.31.7-0.4-1.00.20.3-0.60.70.2
Sr content in liver0.80.71.2-1.11.0-1.1-1.1-0.9-0.9-1.0-1.1-0.8-0.80.8-0.7-0.30.70.5-0.8-0.70.7-0.6-0.8
Zn content in liver0.10.10.1-0.30.3-0.2-0.2-0.3-0.3-0.1-0.10.10.1-0.20.20.4-0.1-0.30.20.2-0.30.30.4
Bone: minimum diameter1.93.68.9-2.93.0-2.8-2.8-2.9-2.9-2.7-2.4-1.2-1.11.0-1.00.61.0-0.2-1.1-1.00.6-0.4-0.8
Time in familiar zone, hab. session 13.53.96.52.4-2.42.62.61.71.72.52.42.11.8-1.91.90.7-1.9-1.11.91.9-1.61.51.5
Time in novel zone, hab. session 12.12.34.5-2.12.1-2.1-2.1-1.1-1.1-2.0-2.1-1.5-1.41.4-1.3-0.31.40.6-1.3-1.41.1-1.0-1.0
Total zone transitions, hab. session 10.60.81.30.7-0.60.70.70.40.40.81.01.01.0-1.11.10.8-1.0-1.01.01.1-1.01.01.0
Total locomotion distance, hab. session 10.50.71.00.9-0.70.90.90.60.60.91.00.90.8-0.91.00.5-0.9-0.70.90.9-0.80.80.6
Locomotion velocity, hab. session 10.30.40.91.0-0.80.80.80.70.70.80.90.60.5-0.50.70.1-0.6-0.30.50.6-0.40.40.3
Time in familiar zone, hab. session 20.40.40.90.9-0.90.90.90.70.70.90.90.60.3-0.50.5-0.0-0.6-0.20.60.5-0.40.40.4
Time in novel zone, hab. session 20.20.20.4-0.50.5-0.5-0.5-0.0-0.0-0.6-0.6-0.6-0.40.5-0.6-0.30.60.4-0.6-0.60.5-0.5-0.4
Total zone transitions, hab. session 20.20.31.40.6-0.70.60.61.21.20.60.50.10.2-0.00.1-0.2-0.10.20.10.00.0-0.0-0.2
Total locomotion distance, hab. session 21.21.62.81.2-1.31.41.41.71.71.41.31.31.2-1.21.30.8-1.3-0.91.31.2-1.11.10.9
Locomotion velocity, hab. session 21.21.62.31.1-1.21.31.31.51.51.31.31.41.3-1.21.30.9-1.3-1.01.31.2-1.21.21.0
Novel to familiar place preference ratio0.10.10.50.6-0.50.40.40.70.70.50.50.00.0-0.10.1-0.40.00.20.10.10.0-0.10.3
Novelty place preference0.10.10.30.3-0.20.20.20.50.50.20.2-0.2-0.20.2-0.1-0.50.30.4-0.2-0.20.3-0.30.0
Time in novel zone, NPP test0.10.10.30.1-0.0-0.1-0.10.30.3-0.1-0.0-0.4-0.40.4-0.3-0.50.40.5-0.4-0.40.4-0.5-0.1
Total zone transitions, NPP test0.91.31.90.7-0.70.90.90.70.70.91.11.31.4-1.31.41.2-1.3-1.31.31.3-1.31.31.1
Total locomotion distance, NPP test1.21.72.21.4-1.31.51.51.31.31.51.51.41.3-1.31.40.7-1.3-0.91.31.2-1.11.11.0
Locomotion velocity, NPP test2.02.83.71.7-1.61.81.81.51.51.91.91.81.8-1.71.81.0-1.7-1.31.81.7-1.61.51.5
Intraocular pressure0.50.81.40.6-0.70.90.90.50.50.80.61.21.1-1.11.00.5-1.1-1.11.11.1-1.11.10.8
Delta distance traveled before/after self-admin1.31.54.1-0.30.5-0.7-0.7-0.1-0.1-0.7-0.7-1.4-1.41.4-1.4-2.01.51.7-1.4-1.41.3-1.5-1.0
Delta ambulatory time before/after self-admin0.71.22.5-0.70.8-1.0-1.0-0.3-0.3-1.0-0.9-1.3-1.41.3-1.2-1.61.31.3-1.3-1.21.2-1.3-1.1
Parametrial fat weight0.81.83.2-0.60.6-0.9-0.9-0.4-0.4-0.9-1.0-1.7-1.61.6-1.6-1.61.71.8-1.6-1.71.8-1.7-1.1
Pavlov. Cond. lever latency1.51.95.32.0-2.01.61.62.32.31.51.2-0.4-0.70.5-0.5-1.90.51.6-0.4-0.50.9-1.0-0.5
Pavlov. Cond. magazine entry latency1.51.95.0-1.61.6-1.1-1.1-2.1-2.1-1.0-0.80.91.2-1.01.02.2-1.1-1.90.91.0-1.41.50.9
Pavlov. Cond. change in total contacts1.61.74.5-1.91.9-1.8-1.8-2.1-2.1-1.8-1.6-0.9-0.50.7-0.80.40.80.0-0.8-0.80.5-0.4-0.7
Pavlov. Cond. index score1.92.46.0-2.02.0-1.5-1.5-2.4-2.4-1.4-1.10.81.1-0.90.92.4-1.0-2.00.80.8-1.31.50.8
Pavlov. Cond. latency score1.82.26.2-2.22.2-1.7-1.7-2.5-2.5-1.6-1.30.40.8-0.60.62.2-0.6-1.70.50.5-1.01.20.6
Pavlov. Cond. lever contacts1.61.95.8-2.02.1-1.7-1.7-2.4-2.4-1.6-1.30.20.5-0.30.31.7-0.4-1.40.20.3-0.70.90.3
Pavlov. Cond. magazine entry number1.62.16.01.1-1.10.60.61.71.70.50.3-1.3-1.61.4-1.4-2.41.52.2-1.3-1.41.7-1.8-1.2
Pavlov. Cond. intertrial magazine entries1.61.95.12.0-2.12.02.02.32.31.91.70.80.8-0.80.8-0.4-0.70.10.80.8-0.50.30.6
Pavlov. Cond. lever-magazine prob. diff.1.92.46.4-1.91.8-1.4-1.4-2.3-2.3-1.2-0.90.91.3-1.11.02.5-1.1-2.11.01.0-1.51.60.9
Pavlov. Cond. response bias1.92.46.5-1.71.6-1.2-1.2-2.2-2.2-1.0-0.81.11.4-1.21.12.6-1.3-2.21.11.2-1.61.71.1
Pavlov. Cond. lever latency0.30.50.7-0.80.8-0.8-0.8-0.5-0.5-0.8-0.7-0.7-0.70.7-0.7-0.60.80.4-0.7-0.70.6-0.6-0.5
Pavlov. Cond. magazine entry latency0.40.61.0-0.81.0-1.0-1.0-1.0-1.0-1.0-0.9-0.8-0.70.7-0.7-0.30.70.5-0.8-0.70.6-0.6-0.7
Pavlov. Cond. change in total contacts0.10.10.30.1-0.20.10.10.50.50.0-0.1-0.5-0.40.4-0.4-0.40.40.6-0.4-0.40.5-0.5-0.3
Pavlov. Cond. index score0.00.10.3-0.20.3-0.2-0.2-0.5-0.5-0.2-0.3-0.1-0.10.1-0.00.2-0.00.0-0.1-0.00.00.0-0.2
Pavlov. Cond. latency score0.00.00.1-0.00.1-0.2-0.2-0.3-0.3-0.2-0.2-0.2-0.20.2-0.2-0.10.20.2-0.2-0.20.2-0.2-0.3
Pavlov. Cond. lever contacts0.20.20.40.6-0.60.60.60.40.40.60.50.40.5-0.40.50.4-0.5-0.30.50.4-0.40.40.3
Pavlov. Cond. magazine entry number0.30.30.50.4-0.50.50.50.60.60.60.70.70.6-0.70.60.4-0.5-0.60.70.6-0.60.60.7
Pavlov. Cond. intertrial magazine entries0.51.22.7-0.80.7-0.3-0.3-1.3-1.3-0.2-0.11.11.1-1.21.11.6-1.1-1.61.11.1-1.31.41.1
Pavlov. Cond. lever-magazine prob. diff.0.00.00.3-0.10.2-0.2-0.2-0.5-0.5-0.2-0.2-0.00.00.00.00.2-0.1-0.0-0.00.1-0.00.1-0.1
Pavlov. Cond. response bias0.10.10.4-0.10.10.00.0-0.3-0.30.00.00.30.4-0.40.40.7-0.5-0.50.40.4-0.40.50.3
Time in closed arm before self-admin0.10.10.3-0.0-0.10.10.10.50.50.20.20.10.5-0.40.30.6-0.2-0.20.30.3-0.10.30.5
Time in closed arm after self-admin0.50.61.50.4-0.70.40.41.21.20.3-0.0-1.0-0.70.7-0.8-0.50.81.0-0.7-0.81.0-1.0-0.4
Time in open arm before self-admin0.20.20.6-0.20.3-0.1-0.1-0.7-0.7-0.1-0.10.40.2-0.50.50.2-0.6-0.80.60.5-0.70.70.6
Time in open arm after self-admin0.30.31.6-0.60.8-0.6-0.6-1.3-1.3-0.6-0.40.40.2-0.20.3-0.2-0.4-0.60.30.3-0.30.5-0.3
Bone: periosteal estimation2.86.611.1-3.23.2-3.3-3.3-2.5-2.5-3.3-3.2-2.6-2.52.4-2.4-0.92.31.4-2.4-2.42.0-1.9-2.1
Bone: periosteal perimeter1.52.95.9-2.42.4-2.4-2.4-2.3-2.3-2.3-2.2-1.4-1.21.2-1.20.01.20.4-1.3-1.20.9-0.8-1.0
Bone: post-yield work1.01.85.0-2.22.1-1.9-1.9-2.0-2.0-1.7-1.8-0.10.1-0.20.01.5-0.2-1.20.10.2-0.60.70.4
Progressive ratio test 1 active lever presses0.30.52.70.9-0.90.80.81.21.20.70.5-0.0-0.30.2-0.1-1.6-0.10.90.0-0.20.5-0.3-0.4
Progressive ratio test 1 breakpoint0.30.52.90.9-0.80.70.71.11.10.60.5-0.1-0.40.2-0.2-1.7-0.00.9-0.0-0.20.5-0.3-0.5
Progressive ratio test 1 inactive lever presses0.41.14.11.6-1.51.31.32.02.01.31.3-0.0-0.0-0.00.0-1.10.10.90.1-0.00.2-0.30.1
Progressive ratio test 2 active lever presses0.50.72.51.1-1.21.21.21.61.61.00.70.40.4-0.40.4-0.7-0.60.20.50.3-0.10.30.0
Progressive ratio test 2 breakpoint0.60.72.71.1-1.21.21.21.61.61.00.70.40.3-0.40.4-0.8-0.60.30.50.3-0.00.2-0.0
Progressive ratio test 2 inactive lever presses0.10.41.4-0.10.3-0.4-0.40.20.2-0.4-0.4-0.8-0.80.6-0.6-1.20.61.0-0.6-0.70.8-0.6-0.6
Incentive Sensitization - Responses0.20.71.10.6-0.70.80.81.01.00.80.60.81.0-0.90.90.6-1.0-0.50.90.8-0.70.90.5
Incentive Sensitization - Breakpoint0.30.71.20.6-0.80.90.91.11.10.90.60.81.0-0.90.90.6-1.0-0.50.90.8-0.80.80.6
Sum of active levers in priming session hrs 5-60.30.30.80.2-0.20.30.3-0.2-0.20.30.20.70.6-0.60.70.0-0.9-0.60.70.6-0.60.70.1
Progressive ratio1.95.510.3-0.70.7-1.2-1.20.00.0-1.4-1.6-2.9-2.82.9-2.8-3.12.83.2-2.7-2.83.0-2.9-2.9
Food seeking constrained by brief footshock0.10.10.50.3-0.20.30.30.10.10.30.30.10.5-0.40.3-0.3-0.2-0.10.30.2-0.10.30.7
Seeking ratio, punishment vs. effort2.14.88.10.8-0.81.31.30.10.11.41.52.62.7-2.82.72.5-2.6-2.82.62.6-2.72.72.9
Retroperitoneal fat weight0.31.52.7-0.50.4-0.7-0.7-0.4-0.4-0.8-1.2-1.4-1.71.4-1.6-1.41.41.6-1.4-1.31.4-1.5-1.4
Reaction time number correct0.20.82.41.4-1.51.31.31.51.51.21.1-0.2-0.20.1-0.1-0.60.40.9-0.1-0.20.5-0.6-0.1
Reaction time mean minus median0.53.510.1-3.23.0-2.6-2.6-2.8-2.8-2.6-2.8-0.2-0.20.2-0.22.0-0.1-1.2-0.2-0.1-0.40.6-0.5
Reaction time mean minus median AUC0.32.36.6-2.62.2-1.9-1.9-2.4-2.4-1.9-2.30.00.1-0.10.12.1-0.4-1.10.00.1-0.50.7-0.4
Reaction time num false alarms0.40.61.3-0.60.7-0.8-0.8-1.1-1.1-0.8-0.5-0.9-0.80.8-0.7-0.30.70.5-0.8-0.70.7-0.7-1.0
Reaction time num false alarms AUC0.40.91.5-0.70.9-1.0-1.0-1.2-1.2-1.0-0.6-1.1-1.01.0-0.9-0.60.90.7-1.0-0.90.9-0.9-1.1
Reaction time trials correct on left0.20.82.41.4-1.51.31.31.51.51.21.1-0.2-0.20.1-0.1-0.60.40.9-0.1-0.20.5-0.6-0.1
Reaction time trials on left0.20.72.01.3-1.41.21.21.41.41.01.0-0.2-0.20.2-0.2-0.50.40.9-0.2-0.20.5-0.6-0.2
Reaction time mean1.43.19.1-2.62.7-2.2-2.2-3.0-3.0-2.1-2.00.30.4-0.40.42.3-0.6-1.70.20.4-0.91.00.1
Reaction time mean AUC1.33.29.4-2.72.7-2.3-2.3-3.1-3.1-2.2-2.10.30.4-0.30.42.3-0.6-1.70.20.4-0.91.0-0.1
Median of all reaction times1.32.06.3-1.92.1-1.7-1.7-2.5-2.5-1.6-1.30.30.5-0.40.51.9-0.5-1.50.30.4-0.80.90.2
Reaction time omissions1.21.95.3-2.32.2-1.9-1.9-2.3-2.3-1.9-1.90.1-0.0-0.00.11.2-0.2-1.20.10.0-0.50.7-0.3
Reaction time false alarm rate0.91.34.1-1.41.7-1.6-1.6-2.0-2.0-1.5-1.1-0.8-0.80.7-0.6-0.20.50.1-0.8-0.70.5-0.4-0.9
Reaction time premature initiation rate0.91.42.6-0.30.5-0.7-0.7-0.4-0.4-0.7-0.6-1.3-1.61.5-1.5-1.61.51.6-1.5-1.41.5-1.5-1.0
Reaction time premature initiations0.61.74.40.5-0.4-0.0-0.00.40.4-0.1-0.1-1.4-1.71.5-1.6-2.01.62.1-1.5-1.51.8-1.8-1.1
Std. dev. reaction times1.24.011.0-3.33.2-2.8-2.8-3.2-3.2-2.8-2.9-0.3-0.50.4-0.31.70.0-1.1-0.4-0.3-0.30.4-0.8
Reaction time trials completed0.20.72.01.3-1.41.21.21.41.41.01.0-0.2-0.20.2-0.2-0.50.40.9-0.2-0.20.5-0.6-0.2
Reaction time trials AUC0.20.82.21.3-1.51.21.21.51.51.11.0-0.1-0.10.1-0.1-0.50.30.8-0.1-0.10.4-0.5-0.1
Run reversals in cocaine runway, females0.40.51.61.3-0.90.90.90.90.91.01.20.1-0.0-0.20.2-1.0-0.20.50.20.10.1-0.10.3
Run reversals in cocaine runway, males2.93.26.3-2.52.5-2.4-2.4-2.5-2.5-2.4-2.3-1.2-1.41.4-1.20.21.00.4-1.3-1.31.0-0.8-1.5
Latency to leave start box in cocaine runway0.10.10.90.1-0.20.20.2-0.0-0.00.20.10.40.2-0.40.30.9-0.2-0.60.30.3-0.40.40.5
Latency to leave start box in cocaine runway, F0.40.52.70.1-0.20.30.3-0.1-0.10.40.50.80.6-0.80.81.7-0.6-1.20.70.7-0.80.81.0
Latency to leave start box in cocaine runway, M0.50.51.0-0.30.2-0.4-0.4-0.0-0.0-0.4-0.8-0.9-0.80.8-1.0-0.80.90.9-0.9-0.90.8-0.9-0.7
Std. dev. time between licks in bursts1.22.37.2-2.42.4-2.1-2.1-2.7-2.7-2.0-1.9-0.4-0.30.4-0.41.10.3-0.8-0.4-0.4-0.20.3-0.1
Total sessions with >9 infusions0.40.52.10.4-0.30.20.20.80.80.1-0.1-0.6-0.90.7-0.6-1.50.51.1-0.5-0.80.9-0.7-0.8
Short access day 1 total inactive lever presses1.73.44.7-1.92.0-2.2-2.2-1.4-1.4-2.2-2.0-2.0-2.01.9-1.8-1.11.81.4-1.9-2.11.8-1.6-1.9
Short access day 10 total inactive lever presses0.00.30.70.10.2-0.0-0.0-0.3-0.30.20.80.50.6-0.60.60.6-0.3-0.50.50.6-0.70.60.8
Short access day 1 total infusions0.10.10.40.5-0.40.40.40.60.60.30.10.2-0.20.00.0-0.6-0.30.10.1-0.10.2-0.0-0.3
Short access day 10 total infusions0.30.42.00.6-0.40.30.30.90.90.30.0-0.6-0.70.5-0.5-1.40.41.0-0.4-0.50.7-0.6-0.5
Short access total infusions0.50.73.50.6-0.40.30.31.01.00.20.0-0.6-1.10.7-0.7-1.90.61.1-0.6-0.81.0-0.9-0.9
Short access day 1 locomotion0.71.22.30.9-0.91.11.10.70.71.10.71.31.4-1.31.30.7-1.5-0.91.41.2-1.21.31.0
Short access day 10 total locomotion0.21.02.4-1.41.2-1.3-1.3-1.3-1.3-1.2-1.6-1.0-0.50.8-0.70.20.70.3-0.8-0.90.7-0.5-0.8
Short access total locomotion0.00.10.4-0.30.3-0.3-0.3-0.3-0.3-0.2-0.6-0.3-0.10.1-0.1-0.4-0.00.2-0.1-0.30.3-0.0-0.2
One hour access (0.3 mA shock)1.21.42.31.0-0.91.11.10.80.81.21.11.41.4-1.41.4-0.1-1.5-0.91.51.2-1.11.31.3
Compulsive drug intake2.13.15.70.2-0.00.50.5-0.8-0.80.81.22.32.1-2.22.31.9-2.2-2.42.22.0-2.32.42.3
One hour access (shock baseline)0.20.52.30.3-0.30.10.10.80.80.0-0.5-0.7-0.70.7-0.7-1.50.51.1-0.6-0.70.9-0.8-0.8
Social response proportion0.20.30.8-0.80.9-0.8-0.8-0.5-0.5-0.8-0.8-0.2-0.30.4-0.3-0.10.40.1-0.4-0.40.2-0.2-0.6
Social responses0.20.30.4-0.50.4-0.5-0.50.20.2-0.5-0.6-0.5-0.60.6-0.6-0.50.60.6-0.6-0.60.6-0.6-0.6
Social time1.72.67.9-2.62.6-2.4-2.4-2.8-2.8-2.2-2.1-0.5-0.30.4-0.41.10.2-0.8-0.4-0.5-0.00.2-0.1
Soleus weight1.64.813.3-3.43.6-3.3-3.3-3.6-3.6-3.1-2.7-1.1-0.80.8-0.80.80.8-0.5-0.9-0.70.3-0.1-0.3
Bone: stiffness0.50.81.80.1-0.2-0.1-0.10.70.7-0.2-0.4-1.1-1.11.1-1.1-1.21.11.3-1.1-1.01.2-1.3-0.9
Tibialis anterior weight0.31.03.51.5-1.51.31.31.91.91.31.3-0.2-0.10.1-0.2-0.90.30.8-0.00.00.3-0.50.6
Time to tail flick, vehicle, before self-admin0.70.92.7-0.10.10.10.1-0.8-0.80.30.20.91.0-1.11.11.7-1.1-1.21.01.0-1.01.21.3
Time to tail flick, vehicle, after self-admin0.30.51.2-0.70.7-0.4-0.4-0.8-0.8-0.3-0.30.60.7-0.80.81.0-0.9-1.10.70.5-0.71.00.8
Time to tail flick, test, before self-admin0.10.10.40.1-0.20.20.20.40.40.20.10.30.1-0.20.30.3-0.2-0.10.30.3-0.30.20.7
Time to tail flick, test, after self-admin0.40.41.4-0.60.4-0.2-0.2-0.6-0.6-0.3-0.40.60.6-0.50.51.2-0.6-1.10.50.5-0.80.70.3
Delta time to tail flick, vehicle, before/after SA0.10.10.40.3-0.50.40.40.60.60.40.30.30.2-0.20.1-0.5-0.2-0.10.20.2-0.20.1-0.0
Delta time to tail flick, test, before/after SA0.30.40.70.6-0.70.70.70.50.50.70.70.70.8-0.70.60.8-0.7-0.70.60.6-0.60.60.1
Tibia length3.18.613.8-3.63.5-3.7-3.7-2.9-2.9-3.7-3.5-2.9-2.72.7-2.9-1.02.71.7-2.8-2.82.4-2.2-2.5
Ambulatory time before self-admin0.10.40.8-0.80.9-0.9-0.9-0.9-0.9-0.9-0.6-0.2-0.50.5-0.4-0.10.4-0.0-0.5-0.60.5-0.3-0.7
Ambulatory time after self-admin1.32.03.0-1.31.7-1.7-1.7-1.2-1.2-1.7-1.3-1.2-1.61.4-1.4-1.71.41.1-1.5-1.41.2-1.2-1.3
Bone: tissue strength3.03.15.2-0.60.8-1.2-1.2-0.4-0.4-1.2-0.8-2.3-2.22.1-2.1-2.32.32.2-2.1-2.12.2-2.3-1.7
Total heroin consumption0.20.20.6-0.50.7-0.6-0.6-0.8-0.8-0.6-0.4-0.1-0.10.1-0.1-0.50.00.0-0.1-0.1-0.00.1-0.2
Bone: trabecular number1.52.84.62.0-1.92.02.01.71.72.12.21.61.7-1.61.60.7-1.6-0.91.61.7-1.41.31.7
Bone: trabecular spacing3.45.06.4-2.12.1-2.4-2.4-1.6-1.6-2.4-2.4-2.5-2.52.4-2.5-1.62.41.9-2.4-2.42.2-2.2-2.2
Bone: trabecular thickness1.11.62.31.4-1.41.51.50.80.81.41.51.41.4-1.31.30.9-1.3-0.91.31.2-1.11.11.0
Bone: trabecular tissue density1.11.93.9-0.70.5-0.8-0.8-0.5-0.5-1.0-1.2-1.6-1.51.7-1.7-1.31.51.6-1.6-1.71.7-1.6-2.0
Water consumed over 24 hours0.00.10.2-0.30.4-0.4-0.4-0.5-0.5-0.3-0.3-0.20.00.0-0.00.20.1-0.1-0.1-0.00.00.00.3
Number of responses in last shaping day0.40.61.1-0.50.6-0.7-0.7-0.2-0.2-0.7-0.6-0.8-1.00.8-0.8-0.90.70.7-0.8-0.90.9-0.7-1.0