Gtse1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Liver mRNA stability Gtse1 0.04 0.03 4.8e-04 0.02 0.01 0.01 0.01 2.1e-03 9.9e-03 1.7e-02 9.7e-03
2 Brain intron excision ratio chr7_118845280_118845605 0.03 0.02 8.1e-04 0.03 0.03 0.02 0.03 8.1e-04 1.2e-03 2.9e-03 1.3e-03
3 Adipose gene expression Gtse1 0.14 0.15 2.9e-03 0 0.01 0.04 0.01 9.4e-02 1.9e-02 1.0e-05 6.7e-02
4 LHb gene expression Gtse1 0.19 0.11 7.3e-03 0.03 0.02 0 0.02 6.5e-02 9.6e-02 3.0e-01 9.3e-02
5 PL gene expression Gtse1 0.04 0.04 9.1e-03 0.02 0.02 0.01 0.02 3.3e-03 3.8e-03 1.6e-02 3.9e-03
6 Liver gene expression Gtse1 0.44 0.09 0.0e+00 0.44 0.46 0.46 0.46 5.4e-53 2.5e-56 2.3e-56 2.4e-56
7 Brain mRNA stability Gtse1 0.02 0.02 1.0e-02 0.01 0.01 0.01 0.01 3.9e-02 2.6e-02 1.3e-02 8.4e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.50.93.00.9-1.11.71.0-0.10.00.1
Area under the delay curve1.41.64.32.1-1.70.31.60.00.41.2
BMI with tail1.86.310.8-3.03.3-2.8-1.52.7-2.2-1.4
BMI without tail0.41.33.5-1.11.3-1.9-1.00.4-0.6-1.0
Body weight1.35.510.1-2.83.2-3.0-2.91.0-0.6-1.4
Weight adjusted by age0.81.22.0-1.21.4-1.0-1.30.4-0.6-1.4
Bone surface0.20.41.20.8-0.81.10.6-0.30.2-0.2
Bone volume0.30.51.40.9-0.91.20.7-0.30.3-0.2
Breakpoint value in progressive ratio session0.70.82.0-0.90.20.10.81.4-1.40.3
Number of licking bursts0.61.02.10.8-0.90.5-0.2-1.51.40.9
Context. condit. distance diff. score0.60.81.8-1.21.40.6-0.40.5-0.6-0.9
Locomotion velocity, session 11.51.74.5-0.80.9-2.1-1.8-1.30.8-0.3
Locomotion distance, session 10.50.61.60.9-0.4-0.7-0.2-1.31.0-0.0
Locomotion velocity, session 23.03.58.8-2.01.7-3.0-2.6-0.40.7-1.0
Locomotion distance, session 20.30.41.40.4-0.2-1.20.60.6-0.5-0.2
Locomotion velocity, session 32.52.95.9-0.81.1-2.0-2.4-2.11.8-1.0
Locomotion distance, session 30.80.92.20.3-0.2-0.9-1.0-1.41.5-0.4
Stereotopy head waving bouts, day 30.40.51.4-0.51.2-0.6-0.5-0.0-0.0-1.0
Stereotopy head waving duration, day 31.01.34.5-1.02.1-0.6-0.90.5-0.6-1.2
Locomotion velocity, session 71.41.53.2-0.71.1-1.8-1.4-0.70.7-1.6
Locomotion distance, session 70.30.41.0-0.60.1-1.0-0.6-0.50.7-0.5
Stereotopy head waving bouts, day 70.91.12.6-0.81.2-0.9-1.2-0.50.4-1.6
Stereotopy head waving duration, day 70.30.41.1-0.41.0-0.1-0.7-0.40.2-1.0
Locomotion velocity, session 83.54.17.7-2.82.6-2.3-1.81.1-1.2-1.8
Locomotion distance, session 80.30.50.9-1.00.8-0.8-0.7-0.0-0.0-0.9
Degree of sensitization distance0.91.02.4-1.60.8-0.7-0.11.3-1.2-0.0
Degree of sensitization stereotypy0.50.51.4-0.60.9-0.5-0.8-0.3-0.0-1.2
Conditioned locomotion0.10.10.2-0.30.40.0-0.20.3-0.10.1
Cocaine response after cond. corrected0.40.41.0-0.50.3-0.7-0.9-0.71.0-0.1
Cocaine response after cond. not corrected0.70.82.5-0.20.1-1.0-0.9-1.21.6-0.3
Cocaine response before conditioning0.30.30.70.7-0.6-0.30.3-0.80.9-0.1
Saline control response0.20.21.0-0.6-0.0-0.4-0.0-0.2-0.1-1.0
Bone: connectivity density0.30.51.10.7-0.91.10.4-0.60.5-0.2
Bone: cortical apparent density1.01.33.01.6-1.31.71.0-0.20.11.0
Bone: cortical area1.11.73.5-1.91.6-1.1-1.21.1-1.2-0.6
Bone: cortical porosity0.91.02.5-1.60.7-0.9-0.81.0-1.2-0.4
Bone: cortical porosity1.11.22.4-1.50.9-1.1-0.91.0-1.3-0.5
Bone: cortical thickness0.30.51.1-0.40.20.20.11.0-1.10.9
Bone: cortical thickness1.82.14.4-1.61.6-0.4-0.42.1-2.1-0.8
Bone: cortical tissue density0.81.02.41.4-1.21.60.8-0.10.10.9
Condit. Reinf. active minus inactive responses0.20.20.90.3-0.9-0.10.0-0.10.30.5
Condit. Reinf. active-inactive response ratio0.80.92.21.1-1.51.10.8-0.00.20.9
Condit. Reinf. active responses0.50.71.60.7-1.3-0.20.0-1.01.30.0
Condit. Reinf. inactive responses0.70.82.00.2-0.5-0.7-0.4-1.41.4-0.9
Incentive salience index mean0.50.61.5-0.5-0.2-1.1-1.2-0.80.9-0.2
Condit. Reinf. lever presses1.72.45.4-1.41.0-1.8-2.3-1.31.2-1.4
Condit. Reinf. active minus inactive responses0.40.61.3-1.0-0.0-1.2-0.40.8-0.7-0.4
Condit. Reinf. active-inactive response ratio0.10.10.1-0.4-0.30.3-0.10.2-0.20.3
Condit. Reinf. active responses1.41.94.3-1.81.0-2.1-0.91.4-1.1-1.0
Condit. Reinf. inactive responses2.43.16.3-2.02.1-2.5-1.11.4-1.0-1.7
Condit. Reinf. lever presses0.60.91.2-1.11.1-1.1-0.60.9-0.6-1.1
Condit. Reinf. lever reinforcers received1.11.54.0-1.50.7-2.0-0.71.2-0.9-1.1
Conditioned reinforcement - actives0.20.41.0-0.8-0.31.0-0.1-0.40.2-0.9
Conditioned reinforcement - inactives0.20.31.5-1.2-0.00.00.10.2-0.5-0.5
Conditioned locomotion0.91.22.8-1.60.9-0.8-1.7-0.50.7-1.0
Patch foraging indifference point 0 sec0.10.20.90.1-0.2-0.1-0.3-0.20.20.9
Patch foraging indifference point AUC0.10.10.40.6-0.50.10.1-0.10.30.4
Delay disc. indifference point, 0s delay0.20.20.6-0.10.5-0.80.10.2-0.20.6
Delay disc. indifference point, 16s delay2.02.15.72.4-2.00.71.8-0.20.31.3
Delay disc. indifference point, 2s delay0.40.41.00.7-0.70.10.90.3-0.21.0
Delay disc. indifference point, 24s delay0.60.62.3-0.10.2-1.50.11.0-0.70.8
Delay disc. indifference point, 4s delay2.52.76.92.6-1.81.12.40.20.41.1
Delay disc. indifference point, 8s delay1.41.74.32.1-1.60.91.70.30.31.0
Indifference point function ln k1.22.14.3-2.11.7-1.6-1.9-0.2-0.0-1.1
Indifference point function log k1.22.14.3-2.11.7-1.6-1.9-0.2-0.0-1.1
Patch foraging total patch changes 0 sec0.10.20.70.4-0.40.2-0.0-0.40.40.8
Patch foraging total patch changes 12 sec0.00.00.10.10.2-0.3-0.2-0.00.00.3
Patch foraging total patch changes 18 sec0.40.61.20.9-0.9-0.3-0.1-1.01.10.2
Patch foraging total patch changes 24 sec0.10.20.50.40.10.4-0.3-0.50.70.5
Patch foraging total patch changes 6 sec0.30.51.41.1-0.50.40.6-0.10.11.2
Patch foraging time to switch 0 sec0.20.41.10.9-0.20.21.10.5-0.6-0.1
Patch foraging water rate 0 sec0.20.51.3-1.10.6-0.9-0.80.6-0.30.1
Patch foraging water rate 12 sec0.61.23.1-1.00.2-1.8-1.5-0.91.10.0
Patch foraging water rate 18 sec0.20.41.1-0.6-0.1-0.7-1.1-0.50.50.2
Patch foraging water rate 24 sec0.30.51.7-1.30.5-0.7-0.50.5-0.40.2
Patch foraging water rate 6 sec0.81.22.90.1-0.8-1.7-1.1-1.21.60.0
Seeking ratio, delayed vs. immediate footshock0.81.02.31.2-1.01.41.5-0.1-0.0-0.1
Distance traveled before self-admin0.40.51.4-0.2-0.20.0-1.0-1.11.2-0.2
Distance traveled after self-admin0.20.31.1-1.10.50.0-0.50.1-0.4-0.4
Extensor digitorum longus weight0.20.61.9-1.21.4-0.5-0.9-0.0-0.2-0.2
Bone: elastic displacement0.40.41.0-0.80.5-0.4-1.0-0.60.40.6
Bone: elastic work2.22.95.4-2.32.1-2.0-1.61.1-1.4-0.7
Bone: endosteal estimation1.32.85.4-2.32.3-1.8-1.60.5-0.6-1.5
Bone: endosteal perimeter1.83.97.6-2.72.6-2.0-2.60.4-0.5-1.5
Epididymis fat weight0.51.73.2-1.81.0-1.6-0.71.6-1.4-0.2
Delta time in closed arm before/after self-admin0.30.20.9-0.1-0.10.20.30.6-0.90.6
Delta time in open arm before/after self-admin1.61.63.60.2-0.1-0.5-1.1-1.91.9-1.5
Diff in mean of infusions in LGA sessions0.91.12.8-1.70.60.3-0.01.4-1.4-0.5
Delay discount exponential model param1.51.64.2-2.01.8-0.1-1.6-0.0-0.4-1.2
Extinction: sum of active levers before priming0.60.71.4-0.80.10.11.21.1-1.20.0
Active lever presses in extinction session 60.90.91.8-1.31.2-0.8-0.51.3-0.9-0.2
Bone: final force1.21.84.2-1.31.5-0.30.12.1-2.0-0.7
Bone: final moment1.52.45.5-1.51.7-0.50.12.3-2.3-0.8
Food consumed during 24 hour testing period3.34.57.2-2.62.4-2.3-2.20.7-1.2-2.7
Glucose0.10.20.4-0.5-0.5-0.4-0.6-0.1-0.20.5
Heart weight1.31.94.2-1.52.0-0.2-0.21.7-1.7-1.1
Delay discount hyperbolic model param1.61.74.5-2.11.8-0.1-1.60.0-0.5-1.2
Intermittent access intake day 1-15 change0.51.13.9-2.00.3-1.1-0.9-0.3-0.7-1.0
Intermittent access intake escalation0.30.61.9-1.4-0.1-0.3-0.7-0.8-0.3-1.1
Intermittent access intake escalation 20.60.61.4-1.1-0.6-1.20.1-0.4-1.0-0.7
Intermitt. access day 1 inactive lever presses0.20.61.8-0.60.2-0.60.51.3-1.2-0.1
Intermitt. access day 15 inactive lever presses0.71.45.0-2.21.00.3-0.81.0-1.4-0.0
Intermitt. access escalation Index0.60.83.20.3-0.51.80.7-0.5-0.21.2
Intermittent access day 1 total infusions0.91.54.4-1.80.9-0.0-2.1-0.91.0-0.0
Intermittent access day 15 total infusions1.31.94.8-2.20.30.6-2.0-1.70.8-0.7
Intermittent access terminal intake (last 3 days)1.82.48.1-2.80.8-0.6-2.4-1.10.4-0.9
Intermittent access total infusions1.51.85.8-2.40.7-0.1-2.1-1.00.5-0.7
Intermittent access day 1 locomotion1.21.62.8-0.7-0.01.6-1.7-1.31.70.7
Intermittent access day 15 total locomotion1.22.16.3-2.41.2-0.0-2.5-0.90.9-0.5
Intermittent access total locomotion1.51.75.0-2.20.9-0.1-2.2-0.90.8-0.7
Intermittent access standard deviation0.81.75.3-2.30.9-1.4-1.20.5-0.9-1.0
Left kidney weight7.133.068.4-7.68.3-6.1-5.63.1-2.9-4.1
Right kidney weight7.233.065.9-7.68.1-6.3-4.93.9-3.7-3.9
Cocaine induced anxiety0.81.22.5-1.10.9-1.30.41.6-1.4-0.5
Post-drug Anxiety1.01.02.4-0.2-0.2-0.61.51.5-1.40.6
Baseline Anxiety0.81.02.40.7-1.01.10.1-1.00.91.6
Tail length0.72.88.50.8-1.3-0.7-1.4-2.92.40.5
Length with tail0.62.66.7-1.10.9-2.2-2.6-1.61.5-0.3
Length without tail1.13.46.9-2.62.4-2.0-1.71.6-1.3-0.5
Times rat made contact with spout1.01.24.5-0.40.6-0.6-1.1-1.00.8-2.1
Lifetime Intake1.51.95.6-2.40.7-0.5-2.0-1.00.6-1.1
Liver weight, left1.42.35.8-1.71.6-2.4-1.9-0.50.6-0.7
Liver weight, right1.42.45.6-1.00.9-2.0-2.4-1.41.8-0.5
Locomotor activity2.33.79.8-2.12.1-2.5-3.1-0.50.90.2
Locomotor testing distance0.40.71.4-0.40.6-1.2-1.2-0.70.90.7
Locomotor testing rearing0.71.33.8-0.91.2-1.9-1.2-1.10.5-0.6
Locomotion in novel chamber1.62.05.41.0-0.30.4-1.4-2.12.3-1.2
Locomotion in novel chamber post-restriction0.30.42.20.40.21.50.80.2-0.10.0
Fecal boli incidents, locomotor time 10.10.20.9-0.40.4-0.9-0.40.1-0.1-0.2
Change in fecal boli incidents, locomotor task0.50.51.60.3-0.0-0.4-0.7-0.60.9-1.3
Time >=10cm from walls, locomotor time 10.30.30.80.10.8-0.6-0.00.9-0.5-0.6
Bouts of movement, locomotor time 10.30.41.1-1.00.5-0.2-0.30.4-0.7-0.8
Total resting periods, locomotor time 10.40.51.3-0.80.5-0.10.20.9-1.2-0.5
Rest time, locomotor task time 10.81.03.7-0.71.0-1.9-0.90.1-0.1-1.0
Distance moved, locomotor task time 10.10.21.1-0.10.3-0.10.10.4-0.11.0
Vertical activity count, locomotor time 10.10.30.70.3-0.20.30.80.6-0.60.7
Time >=10cm from walls, locomotor time 20.30.51.3-0.60.8-0.10.21.1-1.0-0.1
Bouts of movement, locomotor time 20.71.12.00.8-0.61.41.41.1-1.10.6
Total resting periods, locomotor time 20.50.91.80.8-0.81.11.40.9-1.00.5
Rest time, locomotor task time 22.02.65.41.9-1.7-0.7-0.5-2.32.3-0.0
Distance moved, locomotor task time 21.41.64.2-2.01.9-0.7-0.41.2-1.2-0.1
Vertical activity count, locomotor time 21.42.03.9-2.01.9-0.6-0.21.6-1.8-0.5
Light reinforcement 10.51.12.9-0.81.7-0.1-1.7-0.31.0-0.7
Light reinforcement 22.13.26.9-2.62.3-1.8-2.20.7-0.4-1.2
Bone: marrow area1.22.75.3-2.32.3-1.7-1.50.5-0.7-1.4
Bone: maximum diameter3.87.214.4-3.83.3-3.0-2.81.3-1.5-2.0
Bone: maximum force1.52.76.2-1.51.8-0.90.22.5-2.5-0.5
Bone: maximum moment1.93.37.5-1.62.0-1.10.12.7-2.7-0.6
Mean time between licks in bursts0.30.81.91.4-0.80.70.6-0.90.80.9
Mean num. licks in bursts1.21.94.8-1.51.3-1.2-0.61.1-1.2-2.2
Cd content in liver0.20.31.3-0.10.30.50.00.3-0.3-1.1
Co content in liver0.10.10.5-0.0-0.10.1-0.4-0.70.5-0.2
Cu content in liver4.85.810.73.1-2.53.33.20.20.01.9
Fe content in liver0.60.71.6-0.50.7-0.60.31.1-1.2-1.0
K content in liver0.10.10.2-0.20.2-0.10.00.5-0.30.1
Mg content in liver0.30.30.60.2-0.00.70.70.8-0.70.1
Mn content in liver1.01.12.7-1.00.9-1.2-1.6-0.70.80.3
Na content in liver1.11.22.71.7-1.21.31.50.1-0.20.2
Rb content in liver1.82.14.10.30.01.91.81.8-2.0-0.4
Se content in liver0.10.10.50.1-0.2-0.1-0.1-0.60.70.2
Sr content in liver0.90.71.70.9-0.90.1-0.2-1.21.30.6
Zn content in liver0.20.20.60.40.20.80.1-0.70.4-0.5
Bone: minimum diameter1.22.14.2-2.01.5-1.6-2.1-0.30.2-1.3
Time in familiar zone, hab. session 10.90.92.9-0.91.3-0.5-0.70.2-0.4-1.7
Time in novel zone, hab. session 10.30.30.80.3-0.40.90.30.0-0.40.9
Total zone transitions, hab. session 11.41.94.91.8-1.42.21.6-0.30.20.6
Total locomotion distance, hab. session 10.10.20.60.40.00.4-0.0-0.40.8-0.1
Locomotion velocity, hab. session 10.20.21.00.40.0-0.1-0.2-0.51.0-0.2
Time in familiar zone, hab. session 20.40.41.2-0.40.1-0.0-0.7-1.10.9-0.1
Time in novel zone, hab. session 20.50.50.80.8-0.70.70.90.6-0.60.4
Total zone transitions, hab. session 20.50.61.3-0.50.7-0.20.51.1-1.2-1.0
Total locomotion distance, hab. session 20.20.20.4-0.50.4-0.6-0.10.4-0.4-0.7
Locomotion velocity, hab. session 20.20.20.6-0.40.4-0.8-0.10.2-0.3-0.8
Novel to familiar place preference ratio0.30.41.11.1-0.30.30.7-0.80.20.2
Novelty place preference0.20.30.90.8-0.00.20.3-1.00.40.0
Time in novel zone, NPP test0.30.31.00.9-0.10.30.4-1.00.4-0.3
Total zone transitions, NPP test0.50.81.71.2-1.20.91.3-0.0-0.10.5
Total locomotion distance, NPP test0.10.10.30.4-0.5-0.50.50.00.30.4
Locomotion velocity, NPP test0.20.20.50.4-0.6-0.50.4-0.10.40.7
Intraocular pressure0.81.22.8-0.70.4-0.8-1.7-1.01.60.7
Delta distance traveled before/after self-admin0.40.41.0-0.71.0-0.0-0.40.4-0.6-0.9
Delta ambulatory time before/after self-admin0.30.30.9-0.61.00.3-0.20.5-0.8-0.2
Parametrial fat weight0.51.34.01.3-0.9-0.9-0.2-1.32.00.2
Pavlov. Cond. lever latency1.51.94.61.3-0.62.12.01.1-0.80.7
Pavlov. Cond. magazine entry latency0.20.20.7-0.2-0.7-0.8-0.3-0.1-0.10.2
Pavlov. Cond. change in total contacts0.50.51.3-0.8-0.2-1.1-0.80.4-0.40.8
Pavlov. Cond. index score0.40.51.9-0.7-0.2-1.4-0.9-0.20.00.1
Pavlov. Cond. latency score0.50.62.4-0.90.1-1.6-1.1-0.30.1-0.2
Pavlov. Cond. lever contacts1.51.84.4-1.30.4-2.1-2.1-1.00.9-0.3
Pavlov. Cond. magazine entry number0.20.20.70.30.80.70.30.2-0.0-0.4
Pavlov. Cond. intertrial magazine entries0.91.13.00.9-1.31.70.7-0.10.51.1
Pavlov. Cond. lever-magazine prob. diff.0.30.41.2-0.6-0.4-1.1-0.8-0.40.20.3
Pavlov. Cond. response bias0.70.92.9-1.0-0.2-1.7-1.3-0.60.50.1
Pavlov. Cond. lever latency0.60.92.10.9-0.61.40.2-0.90.71.2
Pavlov. Cond. magazine entry latency1.72.04.60.7-1.01.02.12.0-1.80.3
Pavlov. Cond. change in total contacts0.91.43.2-0.5-0.0-1.30.51.8-1.6-1.3
Pavlov. Cond. index score0.60.82.1-0.2-0.2-0.50.81.5-1.2-0.9
Pavlov. Cond. latency score0.70.92.7-0.3-0.1-0.40.81.6-1.4-1.0
Pavlov. Cond. lever contacts0.60.81.8-0.90.4-1.4-0.11.0-0.8-0.9
Pavlov. Cond. magazine entry number0.70.82.0-0.40.6-0.6-1.2-1.41.20.4
Pavlov. Cond. intertrial magazine entries0.60.91.8-1.20.9-0.8-0.01.3-1.4-0.0
Pavlov. Cond. lever-magazine prob. diff.0.50.71.7-0.0-0.3-0.40.81.3-1.0-1.1
Pavlov. Cond. response bias0.40.51.1-0.2-0.2-1.00.51.1-0.8-0.6
Time in closed arm before self-admin1.01.33.60.9-1.60.60.9-0.80.41.9
Time in closed arm after self-admin0.70.82.70.6-0.90.8-0.2-0.90.31.6
Time in open arm before self-admin0.20.20.60.50.4-0.2-0.40.20.4-0.8
Time in open arm after self-admin0.50.62.80.00.4-0.70.00.10.7-1.7
Bone: periosteal estimation1.63.46.8-2.62.5-1.9-1.81.0-1.1-1.4
Bone: periosteal perimeter2.84.89.6-3.02.6-2.5-3.10.2-0.3-1.3
Bone: post-yield work0.71.02.21.0-0.30.41.51.3-1.2-0.6
Progressive ratio test 1 active lever presses0.81.02.6-0.80.00.7-1.6-1.31.30.3
Progressive ratio test 1 breakpoint0.91.02.4-0.7-0.10.8-1.5-1.31.40.2
Progressive ratio test 1 inactive lever presses0.40.51.4-1.10.70.4-1.2-0.10.5-0.3
Progressive ratio test 2 active lever presses0.30.41.9-1.40.1-0.5-0.10.5-0.40.1
Progressive ratio test 2 breakpoint0.30.31.7-1.30.1-0.4-0.20.4-0.30.1
Progressive ratio test 2 inactive lever presses0.30.42.5-1.60.1-0.1-0.40.3-0.30.2
Incentive Sensitization - Responses0.60.91.8-1.20.1-1.10.51.3-1.20.4
Incentive Sensitization - Breakpoint0.81.02.0-1.30.3-1.20.41.4-1.20.3
Sum of active levers in priming session hrs 5-60.30.20.5-0.2-0.3-0.50.70.6-0.6-0.3
Progressive ratio0.20.41.30.3-0.9-1.10.3-0.40.4-0.1
Food seeking constrained by brief footshock0.60.81.4-1.01.1-0.7-0.31.2-1.00.1
Seeking ratio, punishment vs. effort1.31.94.3-1.21.60.90.42.1-2.10.3
Retroperitoneal fat weight1.87.817.5-3.73.2-4.2-2.42.4-1.4-0.7
Reaction time number correct0.20.40.70.7-0.6-0.80.1-0.50.7-0.5
Reaction time mean minus median0.20.50.80.7-0.9-0.9-0.1-0.80.9-0.1
Reaction time mean minus median AUC0.30.61.60.7-0.2-1.3-0.3-0.61.2-0.7
Reaction time num false alarms1.01.52.9-0.2-0.2-1.3-1.2-1.71.5-1.4
Reaction time num false alarms AUC1.01.63.8-0.3-0.2-1.1-1.5-2.01.7-1.1
Reaction time trials correct on left0.20.40.70.7-0.6-0.80.1-0.50.7-0.5
Reaction time trials on left0.20.40.60.7-0.7-0.80.2-0.50.7-0.5
Reaction time mean1.32.14.31.6-1.71.82.10.6-0.41.2
Reaction time mean AUC1.42.24.61.7-1.81.92.10.4-0.20.9
Median of all reaction times2.13.06.21.6-1.72.32.51.0-0.81.6
Reaction time omissions0.60.92.01.4-1.01.31.0-0.10.30.4
Reaction time false alarm rate0.60.92.0-0.70.1-0.6-1.4-1.41.0-0.5
Reaction time premature initiation rate1.41.96.1-0.90.5-0.40.82.3-2.50.4
Reaction time premature initiations0.61.23.3-0.30.0-0.90.91.8-1.8-0.0
Std. dev. reaction times0.40.82.01.2-1.40.60.7-0.40.70.8
Reaction time trials completed0.20.40.60.7-0.7-0.80.2-0.50.7-0.5
Reaction time trials AUC0.20.41.20.5-0.5-1.1-0.0-0.30.6-0.6
Run reversals in cocaine runway, females1.01.02.40.6-0.71.6-0.6-1.21.00.9
Run reversals in cocaine runway, males1.31.33.0-0.60.6-1.4-1.7-1.21.2-0.6
Latency to leave start box in cocaine runway1.11.22.4-1.51.5-1.2-1.10.7-0.5-0.6
Latency to leave start box in cocaine runway, F0.91.02.9-1.31.7-0.9-0.90.5-0.5-0.3
Latency to leave start box in cocaine runway, M0.60.51.0-1.00.3-1.0-0.80.3-0.2-0.9
Std. dev. time between licks in bursts0.40.61.40.2-0.00.40.71.2-0.91.1
Total sessions with >9 infusions1.92.34.9-1.81.5-1.2-1.9-0.40.2-2.2
Short access day 1 total inactive lever presses1.72.26.4-2.52.00.0-1.50.8-1.0-1.1
Short access day 10 total inactive lever presses0.51.12.7-1.00.8-1.6-1.01.1-0.5-1.2
Short access day 1 total infusions0.91.23.1-1.40.80.1-1.8-0.70.4-1.3
Short access day 10 total infusions1.31.75.1-2.11.1-0.5-2.3-0.60.5-0.5
Short access total infusions1.41.85.6-2.41.3-0.5-1.9-0.2-0.1-1.4
Short access day 1 locomotion0.20.31.2-0.60.2-0.5-0.4-0.20.2-1.1
Short access day 10 total locomotion1.12.16.0-0.10.10.4-2.2-1.92.4-0.1
Short access total locomotion0.70.82.1-0.90.5-0.2-1.4-0.80.9-1.1
One hour access (0.3 mA shock)1.11.33.1-1.70.9-1.7-1.0-0.2-0.2-1.1
Compulsive drug intake0.40.51.40.30.3-0.60.81.0-1.2-0.1
One hour access (shock baseline)0.91.44.0-2.00.6-0.5-1.6-0.90.6-1.1
Social response proportion0.60.71.2-1.11.0-0.3-1.00.6-0.7-0.9
Social responses1.11.43.8-1.01.3-1.6-2.0-0.50.6-0.3
Social time0.70.92.60.4-0.50.6-0.9-1.61.50.3
Soleus weight0.30.91.7-1.30.9-1.1-0.41.1-1.10.6
Bone: stiffness1.72.87.90.00.30.41.92.8-2.70.1
Tibialis anterior weight0.41.25.00.9-0.22.21.40.1-0.50.8
Time to tail flick, vehicle, before self-admin0.20.20.60.5-0.10.8-0.2-0.30.50.5
Time to tail flick, vehicle, after self-admin0.20.20.5-0.3-0.1-0.7-0.5-0.60.50.1
Time to tail flick, test, before self-admin1.11.23.2-1.00.9-1.2-1.8-0.50.4-1.3
Time to tail flick, test, after self-admin0.50.61.8-0.7-0.30.40.50.5-0.91.3
Delta time to tail flick, vehicle, before/after SA1.11.02.8-1.01.0-1.7-0.30.9-1.0-0.7
Delta time to tail flick, test, before/after SA1.81.94.20.7-1.31.32.00.5-0.82.1
Tibia length0.30.82.7-1.10.6-1.6-0.7-0.1-0.1-0.7
Ambulatory time before self-admin0.71.02.6-0.1-0.4-0.0-1.1-1.51.6-0.7
Ambulatory time after self-admin0.20.21.0-0.2-0.21.0-0.1-0.6-0.00.3
Bone: tissue strength0.70.71.30.4-0.1-0.11.11.2-1.11.0
Total heroin consumption1.72.06.0-1.41.3-0.60.62.5-1.8-0.8
Bone: trabecular number0.60.91.51.1-1.21.20.4-1.11.0-0.0
Bone: trabecular spacing2.43.25.7-2.02.4-2.4-1.41.3-1.0-1.5
Bone: trabecular thickness0.30.41.00.3-0.71.00.1-0.50.40.9
Bone: trabecular tissue density0.91.42.61.4-1.41.41.60.1-0.41.0
Water consumed over 24 hours0.91.12.4-1.21.2-1.1-1.10.0-0.6-1.5
Number of responses in last shaping day0.30.31.30.7-0.11.20.2-0.30.0-0.5