Gtf3c3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr9_55938738_55941796 0.02 0.02 7.7e-03 0.02 0.02 0.01 0.02 2.9e-03 4.1e-03 4.6e-02 2.4e-03
2 PL alternative TSS NM_001108239.1 0.05 0.04 2.1e-03 0.02 0.02 0.01 0.01 5.8e-03 3.1e-03 2.7e-02 4.2e-02
3 PL alternative TSS XM_039083807.1 0.05 0.04 3.9e-03 0 0.01 0.01 0 1.9e-01 7.2e-03 6.6e-02 7.9e-02
4 PL alternative TSS NM_001108239.1 0.06 0.05 1.9e-03 0 0.02 0.01 0.01 1.5e-01 2.4e-03 3.1e-02 5.3e-02
5 PL alternative TSS XM_039083807.1 0.06 0.05 3.6e-03 0 0.02 0.01 0 2.3e-01 4.6e-03 6.8e-02 1.0e-01
6 Brain alternative TSS NM_001108239.1 0.05 0.03 2.1e-04 0.04 0.04 0.02 0.03 8.3e-05 2.2e-04 2.3e-03 7.5e-04
7 Brain alternative TSS NM_001108239.1 0.06 0.04 1.5e-04 0.04 0.04 0.03 0.03 6.2e-05 1.6e-04 1.7e-03 5.1e-04
8 Brain alternative TSS XM_039083807.1 0.06 0.04 1.4e-04 0.04 0.04 0.03 0.03 5.9e-05 1.4e-04 1.2e-03 4.5e-04
9 Brain alternative TSS XM_039083807.1 0.06 0.04 1.5e-04 0.04 0.04 0.03 0.03 7.2e-05 1.5e-04 9.4e-04 4.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bone: apparent density1.11.812.0-3.50.9-1.00.9-0.9-0.5-0.50.50.5
Area under the delay curve0.20.20.20.20.5-0.50.5-0.5-0.4-0.40.40.4
BMI with tail0.51.78.12.80.4-0.30.3-0.4-1.3-1.31.31.3
BMI without tail0.51.01.50.8-1.21.2-1.21.20.80.8-0.8-0.8
Body weight0.31.35.2-2.3-0.60.6-0.50.51.11.1-1.1-1.1
Weight adjusted by age0.40.41.1-1.00.7-0.70.7-0.7-0.5-0.50.50.5
Bone surface0.91.610.9-3.30.8-0.80.8-0.8-0.4-0.40.40.4
Bone volume1.42.412.8-3.61.2-1.31.3-1.2-0.8-0.80.80.8
Breakpoint value in progressive ratio session0.20.20.5-0.70.4-0.50.5-0.5-0.3-0.30.30.3
Number of licking bursts0.50.60.70.20.8-0.80.8-0.9-0.8-0.80.80.8
Context. condit. distance diff. score1.11.42.61.6-1.21.3-1.31.20.90.9-0.9-0.9
Locomotion velocity, session 10.40.42.61.6-0.20.2-0.30.3-0.5-0.50.50.5
Locomotion distance, session 10.20.20.91.0-0.50.5-0.50.50.20.2-0.2-0.2
Locomotion velocity, session 20.40.52.91.70.00.0-0.10.1-0.7-0.70.70.7
Locomotion distance, session 20.10.10.50.7-0.30.3-0.30.30.10.1-0.1-0.1
Locomotion velocity, session 31.41.72.00.2-1.41.4-1.41.41.31.3-1.3-1.3
Locomotion distance, session 30.20.20.30.3-0.50.5-0.50.50.40.4-0.4-0.4
Stereotopy head waving bouts, day 31.21.42.41.6-1.31.3-1.31.31.01.0-1.0-1.0
Stereotopy head waving duration, day 31.41.72.10.8-1.41.4-1.41.51.21.2-1.2-1.2
Locomotion velocity, session 70.60.73.61.90.1-0.10.00.0-0.8-0.80.80.8
Locomotion distance, session 70.10.10.30.50.2-0.20.2-0.2-0.4-0.40.40.4
Stereotopy head waving bouts, day 70.00.00.0-0.10.0-0.0-0.00.0-0.2-0.20.20.2
Stereotopy head waving duration, day 70.20.20.40.2-0.60.6-0.60.60.30.3-0.3-0.3
Locomotion velocity, session 81.01.21.91.00.8-0.80.7-0.7-1.4-1.41.41.4
Locomotion distance, session 80.71.03.01.7-1.01.0-1.11.10.60.6-0.6-0.6
Degree of sensitization distance0.90.91.1-0.41.1-1.11.0-1.0-1.0-1.01.01.0
Degree of sensitization stereotypy0.40.40.6-0.50.6-0.60.6-0.5-0.8-0.80.80.8
Conditioned locomotion0.50.63.4-1.80.7-0.70.7-0.8-0.0-0.00.00.0
Cocaine response after cond. corrected4.14.65.3-1.92.3-2.32.3-2.3-2.1-2.12.12.1
Cocaine response after cond. not corrected3.84.24.6-2.02.1-2.22.1-2.1-2.0-2.02.02.0
Cocaine response before conditioning0.30.40.50.6-0.70.7-0.70.70.50.5-0.5-0.5
Saline control response0.60.80.90.3-0.90.9-0.90.91.01.0-1.0-1.0
Bone: connectivity density0.71.04.8-2.20.9-0.90.9-0.8-0.6-0.60.60.6
Bone: cortical apparent density0.60.86.42.50.2-0.20.2-0.2-0.5-0.50.50.5
Bone: cortical area0.00.10.4-0.70.1-0.10.1-0.1-0.0-0.00.00.0
Bone: cortical porosity1.01.13.4-1.8-0.70.7-0.70.71.01.0-1.0-1.0
Bone: cortical porosity1.01.15.3-2.3-0.50.5-0.50.51.01.0-1.0-1.0
Bone: cortical thickness0.10.21.31.2-0.00.0-0.00.0-0.2-0.20.20.2
Bone: cortical thickness1.61.92.40.91.3-1.31.3-1.3-1.6-1.61.61.6
Bone: cortical tissue density0.70.96.62.60.2-0.20.2-0.2-0.5-0.50.50.5
Condit. Reinf. active minus inactive responses1.71.92.6-0.81.6-1.61.6-1.6-1.3-1.31.31.3
Condit. Reinf. active-inactive response ratio1.01.11.30.01.2-1.21.2-1.2-1.0-1.01.01.0
Condit. Reinf. active responses2.12.63.4-1.51.8-1.81.8-1.8-1.4-1.41.41.4
Condit. Reinf. inactive responses0.60.71.5-1.20.9-0.90.9-0.9-0.7-0.70.70.7
Incentive salience index mean3.13.74.8-1.02.2-2.22.2-2.2-1.8-1.81.81.8
Condit. Reinf. lever presses1.01.31.8-1.01.3-1.31.3-1.3-1.0-1.01.01.0
Condit. Reinf. active minus inactive responses3.54.48.5-2.92.2-2.22.2-2.2-1.7-1.71.71.7
Condit. Reinf. active-inactive response ratio3.73.94.8-1.62.2-2.22.2-2.2-1.8-1.81.81.8
Condit. Reinf. active responses3.34.55.9-2.42.2-2.32.3-2.3-1.9-1.91.91.9
Condit. Reinf. inactive responses0.20.30.4-0.50.4-0.40.4-0.4-0.6-0.60.60.6
Condit. Reinf. lever presses3.44.65.3-0.42.3-2.32.3-2.3-2.3-2.32.32.3
Condit. Reinf. lever reinforcers received4.15.76.6-2.42.5-2.62.6-2.6-2.2-2.22.22.2
Conditioned reinforcement - actives0.80.81.20.3-1.11.1-1.11.10.70.7-0.7-0.7
Conditioned reinforcement - inactives0.00.10.1-0.1-0.30.3-0.30.30.10.1-0.1-0.1
Conditioned locomotion0.10.10.10.00.3-0.30.3-0.3-0.2-0.20.20.2
Patch foraging indifference point 0 sec2.13.44.10.62.0-2.02.0-2.0-1.9-1.91.91.9
Patch foraging indifference point AUC0.10.10.2-0.40.1-0.10.1-0.1-0.3-0.30.30.3
Delay disc. indifference point, 0s delay0.30.41.81.30.3-0.30.3-0.3-0.5-0.50.50.5
Delay disc. indifference point, 16s delay0.20.20.30.10.5-0.50.5-0.5-0.3-0.30.30.3
Delay disc. indifference point, 2s delay2.42.73.10.21.7-1.71.7-1.7-1.8-1.81.81.8
Delay disc. indifference point, 24s delay0.40.40.50.7-0.50.5-0.50.50.70.7-0.7-0.7
Delay disc. indifference point, 4s delay0.10.10.80.90.2-0.20.1-0.1-0.3-0.30.30.3
Delay disc. indifference point, 8s delay0.00.00.0-0.1-0.00.0-0.10.10.10.1-0.1-0.1
Indifference point function ln k1.11.51.80.81.4-1.31.3-1.3-1.2-1.21.21.2
Indifference point function log k1.11.51.80.81.4-1.31.3-1.3-1.2-1.21.21.2
Patch foraging total patch changes 0 sec2.03.34.00.62.0-2.01.9-2.0-1.9-1.91.91.9
Patch foraging total patch changes 12 sec1.41.92.8-0.31.6-1.61.7-1.7-1.2-1.21.21.2
Patch foraging total patch changes 18 sec1.01.32.61.60.7-0.70.7-0.7-1.3-1.31.31.3
Patch foraging total patch changes 24 sec0.00.00.0-0.00.1-0.10.1-0.1-0.2-0.20.20.2
Patch foraging total patch changes 6 sec0.81.11.40.51.1-1.11.0-1.0-1.2-1.21.21.2
Patch foraging time to switch 0 sec1.62.52.90.6-1.71.7-1.71.71.61.6-1.6-1.6
Patch foraging water rate 0 sec0.30.50.6-0.70.7-0.70.7-0.7-0.8-0.80.80.8
Patch foraging water rate 12 sec3.35.06.0-0.32.3-2.32.3-2.3-2.4-2.42.42.4
Patch foraging water rate 18 sec1.21.61.9-1.31.4-1.41.4-1.4-1.2-1.21.21.2
Patch foraging water rate 24 sec0.10.20.2-0.2-0.50.5-0.50.50.40.4-0.4-0.4
Patch foraging water rate 6 sec0.20.40.4-0.70.5-0.50.5-0.5-0.7-0.70.70.7
Seeking ratio, delayed vs. immediate footshock0.30.42.8-1.70.3-0.30.3-0.3-0.1-0.10.10.1
Distance traveled before self-admin0.60.73.3-1.80.7-0.70.8-0.7-0.3-0.30.30.3
Distance traveled after self-admin0.30.40.50.00.7-0.70.7-0.7-0.6-0.60.60.6
Extensor digitorum longus weight1.03.89.23.0-2.02.1-2.12.11.41.4-1.4-1.4
Bone: elastic displacement1.11.31.6-0.21.2-1.21.3-1.3-1.1-1.11.11.1
Bone: elastic work0.70.93.1-1.81.0-1.01.0-1.0-0.6-0.60.60.6
Bone: endosteal estimation0.71.511.0-3.30.8-0.80.8-0.8-0.2-0.20.20.2
Bone: endosteal perimeter0.51.07.7-2.80.5-0.50.5-0.5-0.0-0.00.00.0
Epididymis fat weight0.81.95.0-2.2-0.80.8-0.70.71.51.5-1.5-1.5
Delta time in closed arm before/after self-admin1.31.21.81.2-1.31.3-1.31.30.80.8-0.8-0.8
Delta time in open arm before/after self-admin1.81.85.6-2.41.4-1.41.4-1.4-0.8-0.80.80.8
Diff in mean of infusions in LGA sessions0.70.81.0-0.61.0-1.01.0-1.0-0.9-0.90.90.9
Delay discount exponential model param0.20.20.3-0.1-0.60.5-0.50.50.40.4-0.4-0.4
Extinction: sum of active levers before priming0.40.43.0-1.70.3-0.30.3-0.30.20.2-0.2-0.2
Active lever presses in extinction session 60.50.51.7-1.30.8-0.80.8-0.8-0.3-0.30.30.3
Bone: final force0.91.43.2-1.8-0.80.7-0.70.71.31.3-1.3-1.3
Bone: final moment0.91.42.4-1.6-0.80.8-0.80.81.41.4-1.4-1.4
Food consumed during 24 hour testing period0.10.20.3-0.6-0.30.3-0.30.30.40.4-0.4-0.4
Glucose2.43.74.60.3-2.01.9-1.91.92.12.1-2.1-2.1
Heart weight0.81.11.2-0.51.1-1.11.1-1.1-1.1-1.11.11.1
Delay discount hyperbolic model param0.20.30.3-0.3-0.50.5-0.50.50.50.5-0.5-0.5
Intermittent access intake day 1-15 change0.20.20.20.2-0.50.5-0.40.40.40.4-0.4-0.4
Intermittent access intake escalation0.10.10.10.1-0.30.3-0.30.30.30.3-0.3-0.3
Intermittent access intake escalation 20.10.10.5-0.7-0.10.1-0.10.10.30.3-0.3-0.3
Intermitt. access day 1 inactive lever presses0.50.50.90.9-0.80.8-0.80.80.50.5-0.5-0.5
Intermitt. access day 15 inactive lever presses0.00.00.00.2-0.10.1-0.10.10.20.2-0.2-0.2
Intermitt. access escalation Index1.81.62.0-0.6-1.31.3-1.21.21.41.4-1.4-1.4
Intermittent access day 1 total infusions0.30.32.1-1.5-0.10.1-0.00.00.40.4-0.4-0.4
Intermittent access day 15 total infusions0.50.51.3-1.2-0.50.5-0.40.40.80.8-0.8-0.8
Intermittent access terminal intake (last 3 days)0.20.21.1-1.1-0.10.1-0.10.10.30.3-0.3-0.3
Intermittent access total infusions0.30.42.2-1.5-0.30.2-0.20.20.50.5-0.5-0.5
Intermittent access day 1 locomotion0.00.00.1-0.30.1-0.10.1-0.1-0.0-0.00.00.0
Intermittent access day 15 total locomotion0.20.21.6-1.30.2-0.30.3-0.30.20.2-0.2-0.2
Intermittent access total locomotion0.20.20.7-0.9-0.10.1-0.10.10.40.4-0.4-0.4
Intermittent access standard deviation0.20.20.4-0.4-0.20.2-0.20.20.60.6-0.6-0.6
Left kidney weight0.10.41.2-1.10.6-0.60.7-0.7-0.3-0.30.30.3
Right kidney weight0.20.61.1-1.10.8-0.90.9-0.9-0.6-0.60.60.6
Cocaine induced anxiety0.10.10.20.2-0.00.0-0.00.0-0.4-0.40.40.4
Post-drug Anxiety0.60.61.10.30.6-0.60.5-0.5-1.1-1.11.11.1
Baseline Anxiety0.10.10.1-0.10.4-0.40.4-0.4-0.1-0.10.10.1
Tail length2.98.824.0-4.9-1.91.8-1.81.83.23.2-3.2-3.2
Length with tail2.38.535.7-6.0-1.41.3-1.31.32.92.9-2.9-2.9
Length without tail0.30.64.9-2.20.3-0.40.4-0.40.30.3-0.3-0.3
Times rat made contact with spout0.50.60.70.0-0.80.7-0.70.70.90.9-0.9-0.9
Lifetime Intake0.30.40.8-0.9-0.50.5-0.50.40.60.6-0.6-0.6
Liver weight, left0.10.22.0-1.40.1-0.10.0-0.0-0.1-0.10.10.1
Liver weight, right0.10.21.4-1.20.0-0.00.00.00.10.1-0.1-0.1
Locomotor activity0.00.10.5-0.7-0.10.1-0.10.1-0.2-0.20.20.2
Locomotor testing distance0.50.81.0-0.50.9-0.90.9-0.9-1.0-1.01.01.0
Locomotor testing rearing0.10.10.4-0.6-0.30.3-0.30.3-0.1-0.10.10.1
Locomotion in novel chamber0.20.30.80.90.3-0.30.3-0.3-0.6-0.60.60.6
Locomotion in novel chamber post-restriction0.20.31.91.4-0.30.3-0.30.30.20.2-0.2-0.2
Fecal boli incidents, locomotor time 11.41.61.8-1.31.2-1.21.1-1.1-1.3-1.31.31.3
Change in fecal boli incidents, locomotor task0.10.10.10.0-0.30.3-0.30.30.30.3-0.3-0.3
Time >=10cm from walls, locomotor time 13.93.94.80.12.1-2.12.0-2.0-2.2-2.22.22.2
Bouts of movement, locomotor time 10.30.40.7-0.30.8-0.80.8-0.8-0.4-0.40.40.4
Total resting periods, locomotor time 10.60.71.00.41.0-1.01.0-1.0-0.7-0.70.70.7
Rest time, locomotor task time 10.10.10.10.3-0.10.1-0.10.00.30.3-0.3-0.3
Distance moved, locomotor task time 10.70.71.2-0.40.6-0.60.6-0.6-1.1-1.11.11.1
Vertical activity count, locomotor time 10.70.71.10.8-1.01.0-1.01.00.60.6-0.6-0.6
Time >=10cm from walls, locomotor time 25.05.36.5-1.32.5-2.52.5-2.5-2.2-2.22.22.2
Bouts of movement, locomotor time 21.81.92.40.41.4-1.41.4-1.4-1.6-1.61.61.6
Total resting periods, locomotor time 22.02.12.60.41.5-1.51.5-1.5-1.6-1.61.61.6
Rest time, locomotor task time 20.80.91.20.6-0.80.8-0.80.81.11.1-1.1-1.1
Distance moved, locomotor task time 21.71.92.6-0.51.3-1.31.3-1.3-1.6-1.61.61.6
Vertical activity count, locomotor time 20.30.30.50.40.4-0.30.3-0.3-0.7-0.70.70.7
Light reinforcement 10.00.10.40.6-0.00.00.1-0.10.30.3-0.3-0.3
Light reinforcement 21.41.92.9-1.41.6-1.61.7-1.7-1.0-1.01.01.0
Bone: marrow area0.71.410.2-3.20.8-0.80.8-0.8-0.2-0.20.20.2
Bone: maximum diameter0.10.21.3-1.20.3-0.30.3-0.3-0.3-0.30.30.3
Bone: maximum force0.71.25.8-2.4-0.40.3-0.30.31.01.0-1.0-1.0
Bone: maximum moment0.61.14.7-2.2-0.40.4-0.40.41.11.1-1.1-1.1
Mean time between licks in bursts1.31.82.20.8-1.51.5-1.51.51.31.3-1.3-1.3
Mean num. licks in bursts0.60.80.9-0.1-0.90.9-0.90.90.90.9-0.9-0.9
Cd content in liver2.22.42.8-0.1-1.61.6-1.61.61.71.7-1.7-1.7
Co content in liver0.60.81.31.1-0.90.9-0.90.90.80.8-0.8-0.8
Cu content in liver0.40.50.7-0.50.8-0.80.8-0.8-0.6-0.60.60.6
Fe content in liver0.50.63.5-1.90.6-0.60.7-0.7-0.1-0.10.10.1
K content in liver0.10.10.10.10.3-0.30.3-0.3-0.3-0.30.30.3
Mg content in liver0.20.20.4-0.60.4-0.40.4-0.4-0.3-0.30.30.3
Mn content in liver0.20.32.31.5-0.10.2-0.20.2-0.0-0.00.00.0
Na content in liver1.11.21.2-1.01.1-1.11.1-1.1-1.1-1.11.11.1
Rb content in liver1.62.02.5-1.01.4-1.41.3-1.3-1.6-1.61.61.6
Se content in liver0.20.30.8-0.90.6-0.60.6-0.6-0.3-0.30.30.3
Sr content in liver3.43.14.00.2-1.71.7-1.71.72.02.0-2.0-2.0
Zn content in liver0.20.20.20.3-0.40.4-0.40.40.50.5-0.5-0.5
Bone: minimum diameter0.10.31.6-1.30.4-0.50.5-0.5-0.1-0.10.10.1
Time in familiar zone, hab. session 11.21.11.60.6-1.21.2-1.21.20.90.9-0.9-0.9
Time in novel zone, hab. session 11.01.01.4-0.51.2-1.21.2-1.2-0.9-0.90.90.9
Total zone transitions, hab. session 10.50.71.10.60.7-0.70.7-0.7-1.0-1.01.01.0
Total locomotion distance, hab. session 11.62.22.8-0.81.7-1.71.7-1.7-1.4-1.41.41.4
Locomotion velocity, hab. session 10.50.71.1-1.10.9-1.01.0-1.0-0.6-0.60.60.6
Time in familiar zone, hab. session 20.30.30.80.90.5-0.50.5-0.6-0.4-0.40.40.4
Time in novel zone, hab. session 20.20.20.6-0.8-0.50.4-0.50.50.40.4-0.4-0.4
Total zone transitions, hab. session 20.70.91.20.3-1.11.1-1.11.10.90.9-0.9-0.9
Total locomotion distance, hab. session 20.50.60.9-0.7-0.70.6-0.60.60.90.9-0.9-0.9
Locomotion velocity, hab. session 20.71.01.3-0.6-0.90.9-0.90.91.21.2-1.2-1.2
Novel to familiar place preference ratio0.70.73.7-1.90.7-0.80.8-0.80.00.0-0.0-0.0
Novelty place preference0.60.63.6-1.90.6-0.60.7-0.70.10.1-0.1-0.1
Time in novel zone, NPP test0.60.63.2-1.80.7-0.80.8-0.8-0.1-0.10.10.1
Total zone transitions, NPP test0.00.00.20.4-0.20.2-0.20.20.00.0-0.0-0.0
Total locomotion distance, NPP test0.30.50.8-0.20.8-0.80.9-0.9-0.5-0.50.50.5
Locomotion velocity, NPP test0.10.20.3-0.10.5-0.50.6-0.6-0.2-0.20.20.2
Intraocular pressure0.30.54.22.10.00.00.0-0.0-0.2-0.20.20.2
Delta distance traveled before/after self-admin0.10.11.11.0-0.10.1-0.00.0-0.1-0.10.10.1
Delta ambulatory time before/after self-admin0.00.00.20.4-0.00.00.0-0.00.20.2-0.2-0.2
Parametrial fat weight0.00.00.1-0.20.0-0.00.0-0.00.20.2-0.2-0.2
Pavlov. Cond. lever latency2.12.73.41.3-1.81.8-1.81.81.51.5-1.5-1.5
Pavlov. Cond. magazine entry latency2.53.24.1-1.02.0-2.02.0-2.0-1.7-1.71.71.7
Pavlov. Cond. change in total contacts4.95.26.4-0.62.5-2.52.5-2.5-2.3-2.32.32.3
Pavlov. Cond. index score2.12.63.6-1.31.8-1.91.9-1.9-1.4-1.41.41.4
Pavlov. Cond. latency score2.43.14.0-1.62.0-2.02.0-2.0-1.6-1.61.61.6
Pavlov. Cond. lever contacts2.02.43.2-1.31.7-1.81.8-1.8-1.3-1.31.31.3
Pavlov. Cond. magazine entry number2.12.63.41.1-1.81.8-1.91.91.41.4-1.4-1.4
Pavlov. Cond. intertrial magazine entries0.30.40.9-1.0-0.50.5-0.50.50.60.6-0.6-0.6
Pavlov. Cond. lever-magazine prob. diff.2.32.83.8-1.01.9-1.91.9-1.9-1.5-1.51.51.5
Pavlov. Cond. response bias1.41.72.4-1.01.5-1.51.5-1.6-1.1-1.11.11.1
Pavlov. Cond. lever latency2.12.83.5-0.5-1.71.6-1.61.61.91.9-1.9-1.9
Pavlov. Cond. magazine entry latency0.10.10.60.8-0.20.2-0.20.2-0.1-0.10.10.1
Pavlov. Cond. change in total contacts3.64.95.80.12.3-2.32.3-2.3-2.4-2.42.42.4
Pavlov. Cond. index score1.62.12.60.31.4-1.41.4-1.4-1.6-1.61.61.6
Pavlov. Cond. latency score1.31.62.00.21.3-1.31.3-1.3-1.4-1.41.41.4
Pavlov. Cond. lever contacts3.34.45.3-0.02.2-2.22.1-2.1-2.3-2.32.32.3
Pavlov. Cond. magazine entry number0.20.30.30.5-0.60.6-0.60.60.60.6-0.6-0.6
Pavlov. Cond. intertrial magazine entries0.10.10.1-0.10.3-0.30.3-0.3-0.2-0.20.20.2
Pavlov. Cond. lever-magazine prob. diff.1.72.22.80.31.5-1.41.4-1.4-1.7-1.71.71.7
Pavlov. Cond. response bias2.02.73.3-0.21.7-1.71.6-1.6-1.8-1.81.81.8
Time in closed arm before self-admin0.91.06.4-2.50.8-0.80.8-0.8-0.2-0.20.20.2
Time in closed arm after self-admin0.90.91.0-0.71.0-1.01.0-1.0-1.0-1.01.01.0
Time in open arm before self-admin2.42.65.22.3-1.71.7-1.61.61.41.4-1.4-1.4
Time in open arm after self-admin0.10.10.7-0.80.1-0.20.2-0.20.10.1-0.1-0.1
Bone: periosteal estimation0.40.96.8-2.60.6-0.60.6-0.6-0.1-0.10.10.1
Bone: periosteal perimeter0.30.64.1-2.00.5-0.50.5-0.5-0.1-0.10.10.1
Bone: post-yield work0.60.81.9-1.4-0.60.6-0.60.61.01.0-1.0-1.0
Progressive ratio test 1 active lever presses0.70.71.0-0.0-1.01.0-1.01.00.70.7-0.7-0.7
Progressive ratio test 1 breakpoint0.40.40.6-0.2-0.80.8-0.80.80.60.6-0.6-0.6
Progressive ratio test 1 inactive lever presses5.25.66.81.3-2.62.6-2.52.52.42.4-2.4-2.4
Progressive ratio test 2 active lever presses1.11.11.7-0.2-1.31.3-1.31.31.01.0-1.0-1.0
Progressive ratio test 2 breakpoint0.50.60.90.0-0.90.9-0.90.90.60.6-0.6-0.6
Progressive ratio test 2 inactive lever presses0.50.60.70.1-0.90.8-0.80.80.80.8-0.8-0.8
Incentive Sensitization - Responses0.50.50.9-0.5-0.90.9-0.90.90.60.6-0.6-0.6
Incentive Sensitization - Breakpoint0.50.60.9-0.4-0.90.9-0.90.90.60.6-0.6-0.6
Sum of active levers in priming session hrs 5-60.40.42.4-1.60.4-0.40.4-0.4-0.1-0.10.10.1
Progressive ratio0.70.92.01.4-0.80.8-0.90.80.80.8-0.8-0.8
Food seeking constrained by brief footshock0.20.30.30.3-0.50.5-0.50.50.50.5-0.5-0.5
Seeking ratio, punishment vs. effort0.20.21.6-1.30.1-0.10.1-0.1-0.1-0.10.10.1
Retroperitoneal fat weight0.20.60.9-0.9-0.60.6-0.50.50.90.9-0.9-0.9
Reaction time number correct0.20.30.30.50.5-0.50.5-0.5-0.6-0.60.60.6
Reaction time mean minus median1.62.13.5-1.4-0.90.8-0.80.81.91.9-1.9-1.9
Reaction time mean minus median AUC0.50.71.2-1.0-0.40.4-0.30.31.11.1-1.1-1.1
Reaction time num false alarms0.91.26.02.5-0.60.7-0.70.60.90.9-0.9-0.9
Reaction time num false alarms AUC1.21.77.02.6-0.90.9-0.90.91.11.1-1.1-1.1
Reaction time trials correct on left0.20.30.30.50.5-0.50.5-0.5-0.6-0.60.60.6
Reaction time trials on left0.10.20.20.40.4-0.40.4-0.4-0.5-0.50.50.5
Reaction time mean1.31.83.0-1.7-0.90.9-0.80.81.61.6-1.6-1.6
Reaction time mean AUC1.62.13.2-1.6-1.11.0-1.01.01.81.8-1.8-1.8
Median of all reaction times0.91.22.4-1.5-0.70.7-0.60.71.31.3-1.3-1.3
Reaction time omissions0.71.01.6-1.3-0.50.5-0.50.51.31.3-1.3-1.3
Reaction time false alarm rate0.91.34.02.0-0.90.9-0.90.91.11.1-1.1-1.1
Reaction time premature initiation rate4.96.67.60.62.7-2.72.7-2.7-2.7-2.72.72.7
Reaction time premature initiations4.56.47.50.92.6-2.62.6-2.6-2.7-2.72.72.7
Std. dev. reaction times0.91.33.5-1.9-0.50.5-0.40.41.41.4-1.4-1.4
Reaction time trials completed0.10.20.20.40.4-0.40.4-0.4-0.5-0.50.50.5
Reaction time trials AUC0.10.10.30.50.3-0.30.3-0.3-0.4-0.40.40.4
Run reversals in cocaine runway, females0.90.81.20.9-1.01.0-1.11.10.70.7-0.7-0.7
Run reversals in cocaine runway, males2.12.02.4-0.21.5-1.51.5-1.5-1.5-1.51.51.5
Latency to leave start box in cocaine runway0.80.97.32.7-0.30.3-0.30.3-0.2-0.20.20.2
Latency to leave start box in cocaine runway, F1.01.17.32.7-0.70.7-0.80.70.20.2-0.2-0.2
Latency to leave start box in cocaine runway, M0.50.51.11.00.5-0.50.5-0.5-0.7-0.70.70.7
Std. dev. time between licks in bursts0.30.32.21.5-0.30.3-0.30.30.30.3-0.3-0.3
Total sessions with >9 infusions0.91.01.21.0-1.11.1-1.11.10.90.9-0.9-0.9
Short access day 1 total inactive lever presses0.70.71.2-0.91.0-1.01.1-1.1-0.5-0.50.50.5
Short access day 10 total inactive lever presses0.00.00.0-0.0-0.10.1-0.10.10.00.0-0.0-0.0
Short access day 1 total infusions0.10.10.2-0.2-0.40.4-0.30.30.40.4-0.4-0.4
Short access day 10 total infusions0.30.32.2-1.50.4-0.40.5-0.50.10.1-0.1-0.1
Short access total infusions0.00.00.1-0.2-0.20.2-0.10.10.30.3-0.3-0.3
Short access day 1 locomotion0.60.70.90.4-0.90.9-0.90.90.80.8-0.8-0.8
Short access day 10 total locomotion0.60.71.2-0.61.1-1.11.1-1.1-0.6-0.60.60.6
Short access total locomotion0.50.50.7-0.2-0.70.7-0.70.70.80.8-0.8-0.8
One hour access (0.3 mA shock)0.30.42.0-1.40.5-0.50.6-0.60.10.1-0.1-0.1
Compulsive drug intake0.00.00.20.5-0.00.0-0.00.00.10.1-0.1-0.1
One hour access (shock baseline)0.40.43.5-1.90.3-0.30.4-0.40.00.0-0.0-0.0
Social response proportion1.01.17.7-2.80.5-0.60.6-0.6-0.5-0.50.50.5
Social responses0.50.73.7-1.9-0.50.5-0.50.50.60.6-0.6-0.6
Social time0.40.51.2-1.1-0.80.7-0.70.70.60.6-0.6-0.6
Soleus weight0.20.40.6-0.80.7-0.70.7-0.7-0.6-0.60.60.6
Bone: stiffness1.62.64.1-2.0-1.31.3-1.31.31.81.8-1.8-1.8
Tibialis anterior weight0.20.82.31.5-0.90.9-0.90.90.60.6-0.6-0.6
Time to tail flick, vehicle, before self-admin1.11.11.21.0-1.01.0-1.01.01.11.1-1.1-1.1
Time to tail flick, vehicle, after self-admin0.10.20.20.4-0.40.4-0.40.40.40.4-0.4-0.4
Time to tail flick, test, before self-admin0.20.20.40.60.5-0.50.5-0.5-0.2-0.20.20.2
Time to tail flick, test, after self-admin1.01.11.41.0-1.21.2-1.21.20.90.9-0.9-0.9
Delta time to tail flick, vehicle, before/after SA0.00.00.1-0.30.1-0.20.2-0.2-0.2-0.20.20.2
Delta time to tail flick, test, before/after SA0.30.30.40.4-0.70.7-0.70.70.30.3-0.3-0.3
Tibia length1.23.410.4-3.2-1.31.2-1.21.21.91.9-1.9-1.9
Ambulatory time before self-admin0.30.31.2-1.10.5-0.50.5-0.5-0.1-0.10.10.1
Ambulatory time after self-admin0.50.50.80.30.8-0.80.9-0.9-0.6-0.60.60.6
Bone: tissue strength3.73.64.6-0.6-1.91.9-1.81.82.12.1-2.1-2.1
Total heroin consumption0.00.00.2-0.4-0.0-0.00.0-0.00.10.1-0.1-0.1
Bone: trabecular number0.50.76.0-2.40.3-0.30.3-0.3-0.1-0.10.10.1
Bone: trabecular spacing0.10.21.41.2-0.10.1-0.10.1-0.3-0.30.30.3
Bone: trabecular thickness0.81.03.0-1.70.9-1.01.0-0.9-0.8-0.80.80.8
Bone: trabecular tissue density0.81.11.30.5-1.01.0-1.01.01.11.1-1.1-1.1
Water consumed over 24 hours0.20.30.40.60.5-0.50.5-0.5-0.5-0.50.50.5
Number of responses in last shaping day2.62.73.61.5-1.91.9-1.91.91.41.4-1.4-1.4