Hub : Genes

Grm5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA isoform ratio XM_017588780.2 0.06 0.04 5.4e-03 0.01 0.01 0.01 0.01 1.5e-01 6.6e-02 8.0e-02 6.7e-02
2 Brain gene expression Grm5 0.55 0.17 0.0e+00 0.26 0.3 0.32 0.32 9.8e-24 1.3e-28 1.9e-30 4.7e-30
3 NAcc gene expression Grm5 0.05 0.03 4.5e-05 0.05 0.03 0.04 0.05 1.4e-06 9.3e-05 1.1e-05 4.1e-06
4 Brain mRNA stability Grm5 0.11 0.06 4.9e-08 0.09 0.07 0.08 0.09 4.7e-09 3.4e-07 7.6e-08 1.3e-08
5 PL gene expression Grm5 0.04 0.02 4.1e-04 0.02 0.03 0.03 0.03 2.7e-03 1.9e-04 1.7e-04 1.2e-04
6 NAcc isoform ratio XM_017588779.2 0.05 0.03 1.3e-05 0.03 0.05 0.04 0.04 9.0e-05 4.8e-06 5.2e-06 6.5e-06
7 Brain isoform ratio XM_017588780.2 0.05 0.03 3.3e-04 0.03 0.03 0.04 0.04 6.0e-04 5.2e-04 2.2e-04 2.2e-04
8 PL isoform ratio XM_006229659.4 0.02 0.01 7.8e-03 0 0.01 0 0 2.3e-01 5.9e-02 1.9e-01 2.6e-01
9 NAcc isoform ratio XM_017588780.2 0.04 0.03 2.1e-04 0.03 0.03 0.03 0.02 1.3e-04 1.1e-04 3.5e-04 8.6e-04
10 OFC gene expression Grm5 0.29 0.14 4.2e-06 0.06 0.25 0.21 0.21 1.7e-02 1.4e-06 1.0e-05 9.1e-06
11 RMTg mRNA stability Grm5 0.21 0.12 4.8e-04 0.08 0.11 0.06 0.07 4.0e-03 6.1e-04 1.1e-02 4.7e-03
12 PL isoform ratio XM_017588779.2 0.04 0.03 6.0e-04 0.04 0.02 0.03 0.04 1.2e-05 2.2e-03 1.0e-04 3.1e-05
13 BLA isoform ratio XM_017588778.2 0.12 0.07 4.1e-04 0.06 0.04 0.04 0.05 3.4e-04 2.2e-03 4.0e-03 8.4e-04
14 Brain isoform ratio XM_017588778.2 0.06 0.04 8.7e-06 0.06 0.06 0.06 0.05 4.4e-06 6.4e-06 6.1e-06 1.0e-05
15 Brain isoform ratio XM_017588779.2 0.04 0.03 1.4e-03 0.03 0.01 0.01 0.01 6.5e-04 1.8e-02 8.6e-02 1.4e-02
16 PL intron excision ratio chr1_141310442_141321054 0.03 0.02 2.7e-03 0.01 0.01 0 0 5.9e-02 6.6e-02 1.2e-01 2.3e-01
17 PL isoform ratio XM_017588778.2 0.07 0.04 7.3e-06 0.01 0.04 0.04 0.04 8.7e-03 1.0e-05 8.8e-05 5.2e-05
18 LHb alternative TSS XM_039096032.1 0.27 0.16 9.2e-03 0.08 0.09 0.03 0.1 6.8e-03 4.5e-03 6.2e-02 2.4e-03
19 LHb alternative TSS XM_039096032.1 0.27 0.16 9.2e-03 0.08 0.09 0.03 0.1 6.8e-03 4.5e-03 6.2e-02 2.8e-03
20 Brain isoform ratio XM_006229659.4 0.04 0.03 2.5e-03 0.04 0.03 0.01 0.03 3.2e-04 9.4e-04 1.8e-02 8.3e-04
21 BLA isoform ratio XM_017588779.2 0.11 0.07 5.7e-04 0.04 0.04 0.02 0.03 2.3e-03 3.2e-03 1.8e-02 9.2e-03
22 NAcc isoform ratio XM_017588778.2 0.04 0.03 1.9e-03 0.03 0.03 0.01 0.03 1.6e-04 6.1e-04 7.5e-03 3.9e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22
Bone: apparent density0.50.91.90.9-1.0-0.3-0.10.7-0.9-0.0-1.10.31.21.21.3-0.5-0.81.3-1.31.4-1.1-1.10.90.9-0.9
Area under the delay curve0.91.02.1-0.70.81.51.5-0.80.41.40.4-1.4-0.30.10.7-1.4-1.40.6-0.61.1-0.8-0.81.01.0-1.0
BMI with tail0.20.61.60.1-0.2-0.4-0.50.3-0.0-0.6-0.20.80.2-0.2-0.20.80.9-0.90.9-0.61.31.3-1.2-1.11.1
BMI without tail0.00.00.20.00.00.20.3-0.3-0.00.30.1-0.2-0.10.20.1-0.00.0-0.0-0.00.1-0.2-0.20.30.4-0.4
Body weight0.10.41.40.5-0.40.0-0.1-0.1-0.60.2-1.00.51.20.61.2-0.6-0.50.4-0.31.00.40.4-0.4-0.30.3
Weight adjusted by age0.50.61.11.0-0.8-0.7-0.80.9-1.0-0.7-0.90.80.90.90.70.20.31.0-1.00.4-0.6-0.60.60.6-0.6
Bone surface0.50.91.91.0-0.9-0.4-0.20.4-1.0-0.0-1.10.21.11.21.3-0.5-0.81.3-1.31.4-1.2-1.21.11.0-1.0
Bone volume0.40.81.60.9-0.9-0.4-0.20.6-1.0-0.1-1.10.31.11.21.2-0.5-0.71.1-1.11.2-0.9-0.90.80.8-0.8
Breakpoint value in progressive ratio session0.70.81.81.2-1.2-1.3-1.21.3-1.2-1.2-1.01.00.90.90.80.80.50.7-0.70.1-0.5-0.50.40.4-0.4
Number of licking bursts0.91.12.31.2-1.4-0.8-0.80.6-1.3-0.3-1.50.61.51.41.0-0.7-0.31.5-1.41.4-0.8-0.80.60.7-0.7
Context. condit. distance diff. score0.30.41.50.3-0.4-0.3-0.40.5-0.5-0.1-0.70.30.80.40.3-0.7-0.31.2-1.20.7-0.4-0.40.50.6-0.6
Locomotion velocity, session 110.911.822.0-4.64.64.64.7-4.44.64.24.3-3.9-4.1-3.8-3.2-1.7-1.7-3.33.3-1.01.71.7-1.5-1.31.3
Locomotion distance, session 10.20.30.6-0.40.80.50.8-0.30.60.20.6-0.2-0.6-0.5-0.80.50.4-0.80.8-0.50.40.4-0.4-0.30.3
Locomotion velocity, session 23.33.910.4-2.52.62.93.2-2.92.33.11.9-2.6-1.7-1.6-0.8-2.2-2.3-1.11.20.60.50.5-0.3-0.20.2
Locomotion distance, session 20.50.71.7-1.01.10.81.0-1.01.00.61.2-0.8-1.2-1.0-0.80.3-0.2-1.31.3-0.90.50.5-0.5-0.40.4
Locomotion velocity, session 31.61.94.5-1.71.82.12.1-1.81.52.01.5-2.0-1.4-1.0-0.6-1.6-1.5-0.40.40.3-0.3-0.30.50.7-0.7
Locomotion distance, session 34.85.212.4-3.12.83.23.1-3.42.73.42.7-3.5-2.5-1.9-1.1-2.9-2.2-1.01.00.4-0.2-0.20.40.5-0.5
Stereotopy head waving bouts, day 34.65.411.53.3-3.3-3.3-3.33.4-2.9-3.2-2.62.92.32.51.52.31.61.5-1.5-0.1-1.0-1.00.80.8-0.8
Stereotopy head waving duration, day 30.80.91.9-1.31.31.31.3-1.01.41.11.3-1.0-1.3-1.2-1.3-0.2-0.7-0.70.7-0.50.20.2-0.1-0.00.0
Locomotion velocity, session 73.33.67.7-2.72.42.42.2-2.52.62.22.8-2.7-2.7-2.0-1.3-1.1-0.8-1.91.9-0.80.30.3-0.10.0-0.0
Locomotion distance, session 72.43.07.1-2.72.12.21.8-2.52.42.12.1-2.1-2.0-2.2-1.1-1.2-0.6-1.81.8-0.41.01.0-0.8-0.70.7
Stereotopy head waving bouts, day 70.40.42.3-0.50.30.60.7-0.90.40.90.5-0.9-0.4-0.0-0.2-1.1-1.50.0-0.00.4-0.5-0.50.50.5-0.5
Stereotopy head waving duration, day 72.12.66.1-1.81.62.22.4-2.21.72.51.6-2.5-1.6-0.8-0.8-2.2-2.4-0.20.20.6-0.8-0.80.80.9-0.9
Locomotion velocity, session 83.84.510.1-2.93.03.03.2-3.22.73.02.2-2.4-2.1-2.3-1.8-1.8-2.0-1.21.3-0.00.90.9-0.7-0.60.6
Locomotion distance, session 80.20.30.60.7-0.6-0.7-0.70.7-0.8-0.6-0.70.50.60.60.4-0.00.00.7-0.70.2-0.4-0.40.50.5-0.5
Degree of sensitization distance1.51.53.81.2-1.3-1.8-1.91.6-1.1-1.9-1.12.01.10.40.31.81.70.1-0.0-0.70.80.8-0.8-0.90.9
Degree of sensitization stereotypy1.81.95.8-1.51.31.82.0-2.11.32.21.2-2.1-1.0-0.6-0.3-2.3-2.4-0.10.10.9-0.4-0.40.50.5-0.5
Conditioned locomotion1.21.54.10.3-0.1-1.0-0.91.00.0-1.40.21.3-0.3-0.6-1.12.02.0-1.21.2-1.81.41.4-1.4-1.51.5
Cocaine response after cond. corrected0.20.31.10.2-0.50.10.1-0.4-0.30.5-0.3-0.50.40.61.1-0.6-1.00.2-0.21.0-0.4-0.40.30.3-0.3
Cocaine response after cond. not corrected0.10.10.5-0.20.00.40.4-0.60.20.60.2-0.6-0.10.10.3-0.3-0.70.0-0.00.5-0.2-0.20.20.2-0.2
Cocaine response before conditioning0.20.21.20.4-0.2-0.3-0.40.4-0.4-0.4-0.30.50.30.2-0.30.30.31.1-1.1-0.1-0.5-0.50.60.5-0.5
Saline control response1.01.47.0-0.0-0.30.40.2-0.7-0.41.0-0.4-1.00.60.81.2-2.6-2.41.0-1.01.7-1.2-1.21.21.2-1.2
Bone: connectivity density1.11.83.61.3-1.4-0.5-0.50.8-1.4-0.2-1.60.51.61.61.7-0.6-1.21.9-1.91.7-1.5-1.51.31.2-1.2
Bone: cortical apparent density0.81.03.9-0.80.8-0.1-0.10.10.9-0.51.5-0.3-1.6-1.1-1.61.31.2-1.21.2-2.00.50.5-0.3-0.30.3
Bone: cortical area0.50.81.90.9-0.9-0.4-0.30.4-1.0-0.1-1.00.21.01.21.4-0.5-0.41.1-1.11.1-1.0-1.00.90.9-0.9
Bone: cortical porosity0.80.92.4-1.11.21.01.1-1.21.01.11.4-1.5-1.4-0.6-0.5-0.7-0.7-0.70.7-0.3-0.6-0.60.70.7-0.7
Bone: cortical porosity0.50.51.4-0.60.70.60.7-0.80.60.71.0-1.2-1.0-0.2-0.3-0.3-0.4-0.40.4-0.2-0.8-0.80.90.9-0.9
Bone: cortical thickness0.10.10.20.3-0.3-0.3-0.2-0.1-0.3-0.1-0.1-0.10.10.40.2-0.3-0.20.4-0.40.1-0.4-0.40.50.4-0.4
Bone: cortical thickness0.30.31.1-0.70.80.40.6-0.70.70.41.0-0.8-1.1-0.5-0.7-0.1-0.2-0.60.6-0.70.00.00.0-0.00.0
Bone: cortical tissue density0.71.03.8-0.70.8-0.2-0.10.10.9-0.51.4-0.3-1.6-1.1-1.61.21.2-1.21.2-2.00.50.5-0.3-0.30.3
Condit. Reinf. active minus inactive responses1.01.23.61.1-0.8-1.4-1.31.9-0.8-1.8-0.61.70.50.2-0.31.91.7-0.20.2-1.10.50.5-0.5-0.40.4
Condit. Reinf. active-inactive response ratio1.82.04.11.8-1.7-1.7-1.42.0-1.8-1.4-1.71.31.71.61.40.40.21.4-1.40.8-1.0-1.01.01.0-1.0
Condit. Reinf. active responses1.41.75.80.9-0.7-1.5-1.41.7-0.5-1.9-0.31.80.1-0.2-0.82.42.1-0.90.9-1.81.01.0-1.0-1.01.0
Condit. Reinf. inactive responses1.92.35.7-0.80.80.20.1-0.21.2-0.41.30.4-1.5-1.6-2.21.91.7-2.12.1-2.41.71.7-1.6-1.71.7
Incentive salience index mean0.40.41.40.3-0.1-0.5-0.41.0-0.1-0.9-0.21.00.1-0.3-0.51.21.0-0.50.5-0.90.80.8-0.7-0.60.6
Condit. Reinf. lever presses1.21.62.8-1.71.61.71.5-1.31.71.21.6-1.0-1.5-1.7-1.2-0.4-0.5-1.41.4-0.81.01.0-0.8-0.70.7
Condit. Reinf. active minus inactive responses1.11.34.0-1.11.20.30.4-0.21.3-0.11.6-0.4-1.7-1.5-2.00.91.2-1.41.4-1.90.80.8-0.7-0.80.8
Condit. Reinf. active-inactive response ratio3.13.38.0-1.41.60.30.3-0.11.7-0.51.80.2-1.9-2.2-2.82.02.3-2.22.2-2.82.02.0-1.8-1.91.9
Condit. Reinf. active responses0.50.72.5-0.91.10.40.5-0.41.00.11.3-0.5-1.4-1.1-1.60.50.7-0.80.8-1.40.40.4-0.3-0.30.3
Condit. Reinf. inactive responses0.81.02.30.4-0.40.10.1-0.3-0.60.5-0.5-0.60.61.01.1-1.4-1.51.3-1.31.3-1.3-1.31.31.3-1.3
Condit. Reinf. lever presses2.12.96.8-2.12.21.11.1-1.32.20.72.5-1.2-2.5-2.3-2.60.20.6-2.02.0-2.11.21.2-1.0-0.90.9
Condit. Reinf. lever reinforcers received0.50.62.1-0.91.10.50.5-0.51.00.21.2-0.5-1.2-1.1-1.40.30.5-0.80.8-1.20.60.5-0.4-0.50.5
Conditioned reinforcement - actives1.61.64.8-0.91.00.2-0.1-0.41.1-0.31.6-0.2-1.8-1.5-1.61.41.3-1.91.8-2.21.21.2-1.0-1.01.0
Conditioned reinforcement - inactives0.50.51.61.0-0.9-1.1-1.30.9-0.8-1.1-0.40.90.30.50.21.11.00.3-0.3-0.5-0.2-0.20.20.2-0.2
Conditioned locomotion1.82.26.50.10.1-0.9-1.10.90.3-1.60.71.3-0.9-1.0-1.52.52.5-1.71.7-2.61.51.5-1.4-1.51.5
Patch foraging indifference point 0 sec0.20.20.70.2-0.1-0.4-0.40.6-0.3-0.4-0.50.70.5-0.10.3-0.20.2-0.40.3-0.00.80.8-0.8-0.80.8
Patch foraging indifference point AUC0.70.72.90.0-0.30.50.4-0.2-0.30.7-0.4-0.60.50.71.0-1.4-1.71.0-1.01.3-0.8-0.80.91.0-1.0
Delay disc. indifference point, 0s delay2.12.34.21.9-1.8-1.1-1.21.9-2.0-1.2-1.70.91.72.02.00.50.51.7-1.71.2-1.3-1.31.41.4-1.4
Delay disc. indifference point, 16s delay1.51.54.9-1.61.51.71.7-1.41.31.61.7-2.2-1.6-0.8-0.3-1.3-1.3-0.30.30.0-0.5-0.50.80.9-0.9
Delay disc. indifference point, 2s delay0.50.62.40.10.21.10.9-0.2-0.30.8-0.6-0.30.80.51.2-0.8-0.81.0-1.01.5-0.4-0.40.50.4-0.4
Delay disc. indifference point, 24s delay1.31.33.7-1.31.31.41.5-1.41.01.51.3-1.9-1.3-0.5-0.1-1.4-1.4-0.00.00.2-0.8-0.81.01.1-1.1
Delay disc. indifference point, 4s delay2.72.96.11.3-1.10.10.10.9-1.50.2-1.6-0.11.72.12.4-1.1-1.12.4-2.42.5-2.0-2.02.12.1-2.1
Delay disc. indifference point, 8s delay0.70.72.1-1.01.11.41.4-1.20.91.40.7-1.0-0.6-0.7-0.4-0.9-0.9-0.20.20.40.20.2-0.1-0.10.1
Indifference point function ln k2.23.15.6-2.22.21.61.6-1.82.21.22.0-1.1-2.0-2.4-2.00.10.4-2.11.9-1.41.71.7-1.7-1.71.7
Indifference point function log k2.23.15.6-2.22.21.61.6-1.82.21.22.0-1.1-2.0-2.4-2.00.10.4-2.11.9-1.41.71.7-1.7-1.71.7
Patch foraging total patch changes 0 sec0.10.20.7-0.20.3-0.1-0.10.30.1-0.10.00.3-0.0-0.5-0.2-0.20.2-0.60.5-0.30.80.8-0.8-0.80.8
Patch foraging total patch changes 12 sec2.12.75.42.1-2.3-1.8-2.02.1-2.2-1.6-2.31.62.32.01.90.10.01.7-1.61.2-0.8-0.80.70.8-0.8
Patch foraging total patch changes 18 sec1.82.34.92.0-2.0-1.8-1.92.2-2.0-1.8-1.81.61.81.71.30.60.71.5-1.60.6-0.9-0.90.80.8-0.8
Patch foraging total patch changes 24 sec1.21.56.11.6-1.3-1.5-1.52.5-1.4-1.9-1.31.61.21.10.61.11.30.8-0.7-0.1-0.1-0.10.20.2-0.2
Patch foraging total patch changes 6 sec0.50.82.20.6-0.7-0.2-0.20.4-0.80.2-1.0-0.11.00.91.3-1.4-1.01.0-0.91.5-0.9-0.90.80.9-0.9
Patch foraging time to switch 0 sec6.810.419.54.4-4.3-3.5-3.63.7-4.3-3.0-3.82.63.74.23.41.01.03.3-3.22.0-2.8-2.82.62.4-2.4
Patch foraging water rate 0 sec3.55.711.7-3.33.42.62.8-2.73.12.32.6-1.8-2.4-3.2-2.2-1.0-1.0-2.32.1-1.22.32.2-2.0-1.81.8
Patch foraging water rate 12 sec10.115.527.6-5.25.34.04.3-4.35.13.34.6-2.9-4.4-5.2-4.4-0.7-0.4-4.34.2-2.63.63.6-3.3-3.13.1
Patch foraging water rate 18 sec15.420.741.2-6.26.45.45.7-5.36.14.55.3-3.8-5.0-5.9-4.8-1.6-1.2-4.44.4-2.33.63.6-3.2-3.13.1
Patch foraging water rate 24 sec3.85.310.6-3.13.33.03.1-2.53.02.52.0-1.5-1.7-3.0-2.4-1.1-0.7-1.92.0-0.52.32.3-2.2-2.12.1
Patch foraging water rate 6 sec5.37.713.9-3.73.73.13.2-3.23.62.63.1-2.2-3.0-3.6-2.7-0.7-0.6-2.92.8-1.52.52.5-2.3-2.32.3
Seeking ratio, delayed vs. immediate footshock0.10.10.8-0.30.60.90.6-0.50.20.60.0-0.1-0.0-0.20.1-0.5-0.5-0.00.00.30.30.3-0.2-0.00.0
Distance traveled before self-admin1.31.42.81.7-1.5-1.1-1.21.2-1.6-0.9-1.40.91.31.61.30.20.11.2-1.20.8-1.2-1.21.11.1-1.1
Distance traveled after self-admin2.12.34.42.0-1.9-1.3-1.31.4-1.9-0.8-1.70.91.72.11.6-0.2-0.51.8-1.71.2-1.7-1.71.61.5-1.5
Extensor digitorum longus weight0.00.10.30.2-0.00.10.00.2-0.1-0.0-0.40.30.40.10.10.20.1-0.10.10.30.40.4-0.5-0.60.6
Bone: elastic displacement0.30.41.0-0.40.40.0-0.10.10.4-0.20.20.4-0.2-0.7-0.80.30.6-0.70.7-0.61.01.0-1.0-0.90.9
Bone: elastic work0.20.30.8-0.00.1-0.2-0.00.10.2-0.20.10.4-0.1-0.3-0.50.40.4-0.90.9-0.50.70.7-0.8-0.80.8
Bone: endosteal estimation0.51.14.30.9-0.60.00.20.0-1.00.5-1.40.11.61.41.9-1.0-1.11.1-1.12.1-0.7-0.70.50.6-0.6
Bone: endosteal perimeter0.51.13.81.2-1.1-0.7-0.50.5-1.3-0.2-1.50.41.61.52.0-0.6-0.61.0-1.01.6-0.9-0.90.70.7-0.7
Epididymis fat weight0.61.43.21.6-1.7-1.5-1.40.9-1.6-1.1-1.81.41.81.41.50.30.21.2-1.10.9-0.3-0.20.20.1-0.1
Delta time in closed arm before/after self-admin2.22.15.5-2.01.92.32.3-1.91.82.21.3-1.9-1.2-1.3-0.6-1.7-1.6-0.80.80.50.50.5-0.5-0.40.4
Delta time in open arm before/after self-admin0.10.10.3-0.1-0.10.0-0.1-0.3-0.00.20.1-0.3-0.00.20.2-0.5-0.50.2-0.20.2-0.5-0.50.40.4-0.4
Diff in mean of infusions in LGA sessions0.91.03.10.2-0.00.70.8-0.2-0.40.9-0.5-0.70.60.81.4-1.4-1.41.1-1.21.8-1.1-1.11.01.1-1.1
Delay discount exponential model param0.80.82.00.6-0.8-1.4-1.40.8-0.4-1.3-0.31.30.3-0.1-0.71.31.3-0.60.6-1.10.70.7-0.9-0.90.9
Extinction: sum of active levers before priming0.90.82.40.7-0.5-1.0-1.00.9-0.5-1.2-0.51.40.4-0.1-0.21.41.6-0.60.5-0.91.01.0-1.0-1.11.1
Active lever presses in extinction session 60.80.82.50.9-0.9-1.6-1.31.6-0.7-1.6-0.31.10.20.40.01.41.3-0.20.2-1.00.00.0-0.0-0.00.0
Bone: final force0.50.72.70.9-0.8-0.20.00.1-0.90.2-1.30.41.41.21.5-0.8-1.00.9-0.91.7-0.4-0.40.20.2-0.2
Bone: final moment0.30.62.10.8-0.7-0.20.00.1-0.80.2-1.30.51.41.01.3-0.5-0.70.6-0.61.5-0.1-0.1-0.1-0.10.1
Food consumed during 24 hour testing period1.72.05.80.0-0.31.00.8-1.2-0.31.6-0.4-1.30.51.01.5-2.4-2.21.5-1.52.1-1.7-1.71.61.7-1.7
Glucose0.50.81.8-1.41.20.80.8-1.31.30.91.2-0.9-1.1-1.2-1.2-0.20.0-0.70.7-0.50.70.7-0.6-0.50.5
Heart weight0.81.22.2-1.31.30.70.9-1.11.30.61.2-0.5-1.2-1.5-1.30.00.4-1.41.4-1.11.11.1-1.0-0.90.9
Delay discount hyperbolic model param0.90.92.00.3-0.5-1.2-1.20.5-0.0-1.20.01.1-0.1-0.5-1.11.41.3-1.01.0-1.40.90.9-1.1-1.21.2
Intermittent access intake day 1-15 change0.80.82.40.00.2-0.4-0.40.10.2-0.5-0.11.20.0-0.8-1.01.01.1-0.50.5-1.01.51.5-1.6-1.41.4
Intermittent access intake escalation1.21.12.9-0.20.4-0.3-0.30.00.4-0.50.31.1-0.3-1.2-1.31.21.2-0.90.8-1.41.71.7-1.7-1.51.5
Intermittent access intake escalation 21.01.02.60.00.2-0.4-0.30.40.2-0.7-0.01.2-0.0-0.8-1.01.31.3-0.80.8-1.21.61.6-1.6-1.51.5
Intermitt. access day 1 inactive lever presses1.51.64.0-0.70.81.91.6-1.30.51.90.3-1.6-0.20.20.6-2.0-2.00.8-0.81.7-1.1-1.11.21.4-1.4
Intermitt. access day 15 inactive lever presses0.20.20.7-0.40.40.80.8-0.50.30.70.3-0.6-0.3-0.10.0-0.4-0.40.2-0.20.4-0.3-0.30.30.4-0.4
Intermitt. access escalation Index0.60.51.7-0.1-0.10.20.3-0.4-0.10.60.1-1.1-0.10.60.9-1.3-1.30.2-0.20.8-1.0-1.01.01.0-1.0
Intermittent access day 1 total infusions0.80.94.40.5-0.5-1.0-1.21.2-0.3-1.50.40.7-0.5-0.1-0.42.12.1-0.80.8-1.60.20.1-0.2-0.20.2
Intermittent access day 15 total infusions1.82.07.10.2-0.0-1.0-1.21.00.1-1.60.51.4-0.7-1.0-1.42.72.7-1.31.3-2.31.41.4-1.4-1.31.3
Intermittent access terminal intake (last 3 days)2.22.410.00.8-0.5-1.6-1.71.6-0.4-2.20.21.9-0.4-0.6-1.23.23.1-1.01.1-2.51.21.2-1.2-1.11.1
Intermittent access total infusions1.51.67.00.8-0.6-1.4-1.61.4-0.4-1.90.21.4-0.4-0.3-0.82.62.6-0.90.9-2.10.60.6-0.6-0.60.6
Intermittent access day 1 locomotion0.30.31.2-0.60.60.60.40.10.70.01.0-0.6-1.1-0.5-0.60.70.6-0.70.7-0.8-0.2-0.20.30.2-0.2
Intermittent access day 15 total locomotion1.61.73.1-1.21.40.90.9-0.61.40.41.6-0.4-1.7-1.7-1.71.11.1-1.81.7-1.81.21.2-1.2-1.11.1
Intermittent access total locomotion0.40.41.1-0.50.60.40.3-0.00.70.00.9-0.2-1.0-0.7-0.80.80.8-0.90.9-1.00.30.3-0.3-0.30.3
Intermittent access standard deviation1.92.06.01.4-1.2-1.8-1.81.9-1.2-2.1-1.32.41.20.3-0.32.12.10.1-0.1-0.91.11.1-1.1-1.11.1
Left kidney weight1.23.47.62.7-2.5-2.8-2.62.3-2.5-2.4-2.22.32.12.21.71.21.21.2-1.20.2-0.7-0.70.70.7-0.7
Right kidney weight0.31.01.81.2-1.1-0.9-0.70.2-1.3-0.3-1.30.71.31.41.2-0.8-0.81.3-1.30.9-0.7-0.70.80.8-0.8
Cocaine induced anxiety0.60.72.1-0.20.10.80.7-0.7-0.11.0-0.2-0.80.30.40.6-1.5-1.40.9-0.91.4-0.6-0.60.70.9-0.9
Post-drug Anxiety1.11.33.2-1.00.71.11.1-1.00.71.21.0-1.8-0.9-0.1-0.1-1.5-1.50.5-0.50.5-1.1-1.21.41.7-1.7
Baseline Anxiety3.03.26.9-2.62.42.22.2-2.22.51.82.6-2.3-2.6-2.0-1.8-0.9-0.8-1.61.6-1.10.30.3-0.2-0.10.1
Tail length0.41.32.61.2-0.9-0.5-0.30.4-1.2-0.1-0.90.00.81.51.5-0.6-0.81.4-1.51.0-1.6-1.61.61.6-1.6
Length with tail0.41.54.41.0-0.8-0.00.00.1-1.20.4-1.50.11.61.52.1-1.3-1.41.7-1.62.0-1.0-1.00.90.9-0.9
Length without tail0.10.31.1-0.00.10.40.2-0.2-0.20.4-0.70.30.90.10.8-0.9-0.70.5-0.41.00.50.5-0.6-0.60.6
Times rat made contact with spout0.50.51.60.0-0.20.60.5-0.50.00.80.1-0.8-0.10.50.2-0.6-0.70.5-0.50.8-1.2-1.21.21.3-1.3
Lifetime Intake2.22.59.91.1-0.9-1.9-2.11.9-0.7-2.4-0.22.0-0.1-0.2-0.83.13.1-0.90.9-2.31.01.0-1.0-1.01.0
Liver weight, left1.52.57.62.0-1.7-1.2-1.21.9-1.9-1.2-2.72.42.71.51.80.61.00.7-0.81.31.01.0-1.2-1.11.1
Liver weight, right3.76.212.43.4-3.0-2.3-2.32.7-3.4-2.0-3.52.43.53.23.20.10.22.9-2.92.1-1.5-1.51.41.3-1.3
Locomotor activity2.74.310.0-2.82.82.73.0-2.52.62.62.7-3.2-2.6-1.9-1.5-2.1-2.0-1.31.2-0.2-0.1-0.10.30.5-0.5
Locomotor testing distance1.83.17.2-2.42.41.82.2-1.92.31.72.7-2.4-2.7-1.9-1.7-1.1-1.1-1.71.6-1.10.30.3-0.00.1-0.1
Locomotor testing rearing1.31.94.3-2.01.81.31.4-1.61.91.22.1-1.8-2.0-1.6-1.6-0.8-0.7-1.31.4-0.90.70.7-0.5-0.40.4
Locomotion in novel chamber0.80.92.7-0.91.21.51.6-1.10.81.40.9-1.5-0.9-0.30.3-1.1-1.10.1-0.10.5-0.7-0.70.80.8-0.8
Locomotion in novel chamber post-restriction2.02.45.1-1.31.50.30.3-0.61.3-0.11.10.4-1.1-2.0-1.91.01.0-1.81.9-1.92.22.2-2.1-2.12.1
Fecal boli incidents, locomotor time 10.30.41.5-0.50.30.70.7-0.80.50.80.5-1.2-0.50.10.2-0.8-0.80.1-0.10.6-0.5-0.50.50.6-0.6
Change in fecal boli incidents, locomotor task0.10.10.30.3-0.4-0.4-0.60.2-0.3-0.3-0.20.30.20.10.10.00.00.1-0.0-0.2-0.2-0.20.10.1-0.1
Time >=10cm from walls, locomotor time 11.41.42.71.3-1.5-0.7-0.90.6-1.3-0.3-1.00.11.01.51.3-0.3-0.31.5-1.51.2-1.5-1.51.61.6-1.6
Bouts of movement, locomotor time 10.91.02.3-1.51.11.31.4-1.51.41.41.2-1.5-1.1-1.0-0.7-0.8-0.8-0.70.70.10.30.3-0.2-0.30.3
Total resting periods, locomotor time 11.01.12.3-1.51.11.21.3-1.41.51.31.2-1.2-1.1-1.2-0.9-0.6-0.5-1.01.0-0.10.70.7-0.7-0.80.8
Rest time, locomotor task time 10.30.40.7-0.80.50.80.6-0.80.80.70.1-0.3-0.0-0.7-0.6-0.5-0.4-0.30.20.40.70.7-0.8-0.80.8
Distance moved, locomotor task time 10.30.30.91.0-0.5-0.8-0.30.9-0.9-0.6-0.80.80.70.70.80.50.50.4-0.30.1-0.2-0.20.30.3-0.3
Vertical activity count, locomotor time 12.12.24.22.1-1.9-1.6-1.31.6-2.0-1.2-1.91.41.81.91.90.40.41.5-1.51.0-1.0-1.01.21.0-1.0
Time >=10cm from walls, locomotor time 23.03.18.21.2-1.6-0.6-0.80.3-1.5-0.0-0.8-0.70.81.92.1-1.2-1.22.1-2.11.6-2.6-2.62.92.9-2.9
Bouts of movement, locomotor time 20.60.72.3-1.00.91.11.1-1.00.81.20.9-1.5-0.9-0.3-0.2-1.2-1.2-0.10.10.4-0.4-0.40.40.4-0.4
Total resting periods, locomotor time 20.40.41.7-0.80.80.80.8-0.70.70.80.9-1.3-0.9-0.3-0.3-0.8-0.7-0.20.20.1-0.4-0.40.40.4-0.4
Rest time, locomotor task time 20.70.82.41.1-0.8-1.2-0.91.4-0.9-1.2-1.11.51.00.60.11.41.40.5-0.5-0.10.20.2-0.3-0.30.3
Distance moved, locomotor task time 20.80.92.31.3-1.3-0.8-0.81.1-1.4-0.7-1.40.91.51.31.5-0.0-0.00.8-0.70.9-0.4-0.40.50.4-0.4
Vertical activity count, locomotor time 24.14.410.02.8-3.2-2.3-2.62.1-2.8-1.8-2.71.72.72.82.50.00.02.0-2.01.5-1.5-1.41.41.2-1.2
Light reinforcement 16.211.323.84.7-4.8-4.7-4.84.5-4.4-4.2-4.74.94.63.32.32.12.02.1-2.20.9-0.1-0.1-0.4-0.50.5
Light reinforcement 211.815.833.95.5-5.4-5.6-5.85.5-5.1-5.3-5.15.85.03.73.03.33.22.1-2.20.40.10.1-0.6-0.80.8
Bone: marrow area0.51.14.21.0-0.7-0.10.10.1-1.10.4-1.40.11.61.42.0-1.0-1.11.1-1.12.0-0.8-0.80.60.6-0.6
Bone: maximum diameter0.20.41.50.6-0.4-0.30.10.2-0.70.0-0.80.10.80.91.2-0.5-0.40.7-0.71.0-0.6-0.60.50.6-0.6
Bone: maximum force0.20.42.00.5-0.40.10.2-0.3-0.50.5-1.00.11.10.81.2-0.7-0.90.4-0.41.4-0.2-0.20.0-0.00.0
Bone: maximum moment0.20.31.40.5-0.40.00.2-0.3-0.50.4-0.90.21.00.61.1-0.5-0.60.1-0.21.20.10.1-0.2-0.20.2
Mean time between licks in bursts2.73.811.22.3-2.4-3.2-3.23.1-1.9-3.3-1.42.51.21.30.12.82.40.4-0.4-1.3-0.2-0.20.10.0-0.0
Mean num. licks in bursts1.01.23.0-1.41.41.31.3-1.11.50.91.7-1.2-1.7-1.3-1.00.3-0.1-1.31.3-1.00.20.2-0.0-0.00.0
Cd content in liver2.93.29.02.2-2.2-3.0-2.82.5-1.9-2.9-1.32.21.01.30.02.42.50.6-0.5-1.2-0.5-0.50.50.4-0.4
Co content in liver0.40.51.8-0.30.1-0.0-0.10.00.4-0.11.2-1.1-1.3-0.0-0.3-0.0-0.2-0.50.7-0.8-1.0-1.01.01.0-1.0
Cu content in liver1.62.05.60.0-0.20.60.5-0.3-0.30.80.3-1.6-0.31.01.4-1.4-1.61.4-1.21.3-2.3-2.32.42.4-2.4
Fe content in liver0.20.30.80.8-0.6-0.8-0.90.7-0.8-0.6-0.70.70.70.70.50.3-0.20.2-0.10.10.10.1-0.1-0.10.1
K content in liver0.70.71.31.1-1.1-0.6-0.91.1-1.0-0.5-1.00.70.91.01.00.50.41.0-0.90.5-0.8-0.80.80.7-0.7
Mg content in liver0.80.82.20.3-0.30.50.3-0.1-0.40.7-0.2-0.70.20.81.0-0.7-0.70.9-0.91.0-1.5-1.51.51.5-1.5
Mn content in liver0.10.10.4-0.50.60.60.4-0.20.50.40.5-0.2-0.5-0.6-0.60.00.2-0.10.1-0.40.20.2-0.1-0.10.1
Na content in liver3.33.59.5-0.60.72.22.2-1.50.22.4-0.1-2.20.30.81.8-3.0-3.11.4-1.32.8-2.0-2.02.02.1-2.1
Rb content in liver1.01.32.81.3-1.1-0.6-0.70.5-1.4-0.2-1.60.71.71.51.5-0.9-0.91.6-1.51.5-0.9-0.90.70.6-0.6
Se content in liver1.11.32.61.3-1.3-0.5-0.71.3-1.3-0.6-1.30.51.31.51.6-0.10.11.4-1.11.2-1.3-1.31.21.2-1.2
Sr content in liver1.11.02.5-1.21.31.11.5-1.21.11.21.3-1.6-1.3-0.7-0.6-1.1-0.6-0.40.5-0.1-0.5-0.50.60.7-0.7
Zn content in liver0.40.50.70.8-0.8-0.7-0.80.7-0.8-0.6-0.50.30.40.80.60.30.40.9-0.80.2-0.8-0.80.80.8-0.8
Bone: minimum diameter2.13.99.02.3-2.5-1.4-1.41.2-2.3-0.7-2.40.82.52.73.0-0.6-0.62.4-2.42.4-2.0-2.01.81.7-1.7
Time in familiar zone, hab. session 10.20.20.50.3-0.5-0.5-0.50.7-0.2-0.5-0.50.60.60.10.10.30.5-0.10.10.20.40.4-0.6-0.50.5
Time in novel zone, hab. session 10.10.10.2-0.00.20.10.2-0.3-0.00.20.2-0.3-0.20.10.3-0.2-0.5-0.10.1-0.1-0.3-0.30.40.4-0.4
Total zone transitions, hab. session 12.63.611.0-2.52.72.93.3-2.52.42.71.9-2.2-1.7-1.9-1.3-1.8-1.5-1.31.30.30.70.7-0.6-0.50.5
Total locomotion distance, hab. session 116.022.746.86.8-6.5-6.8-6.56.8-6.3-6.5-5.96.55.75.03.64.03.62.8-2.80.4-1.0-1.00.60.4-0.4
Locomotion velocity, hab. session 116.323.148.36.8-6.4-6.9-6.66.9-6.3-6.7-5.96.65.54.93.44.33.92.7-2.80.1-1.0-0.90.60.3-0.3
Time in familiar zone, hab. session 20.40.40.90.5-0.8-0.4-0.4-0.0-0.7-0.1-0.90.31.00.70.7-0.6-0.70.9-0.90.9-0.4-0.40.30.3-0.3
Time in novel zone, hab. session 21.21.23.6-1.01.10.40.5-0.41.20.11.8-0.8-1.9-1.2-1.40.80.9-1.81.7-1.80.50.5-0.4-0.40.4
Total zone transitions, hab. session 21.72.24.9-1.91.91.92.2-1.91.91.81.9-1.9-1.9-1.4-1.2-0.8-0.8-1.51.5-0.40.60.6-0.5-0.50.5
Total locomotion distance, hab. session 219.125.353.47.2-6.9-7.3-6.97.2-6.6-7.0-6.06.85.75.33.64.84.12.7-2.80.1-1.0-0.90.50.4-0.4
Locomotion velocity, hab. session 218.224.550.17.1-6.7-7.1-6.77.0-6.5-6.8-6.16.85.85.23.54.74.02.8-2.80.2-0.8-0.80.40.2-0.2
Novel to familiar place preference ratio0.30.41.20.5-0.7-1.0-1.10.8-0.4-0.9-0.10.70.00.1-0.10.91.1-0.30.3-0.80.20.2-0.2-0.10.1
Novelty place preference0.30.41.20.2-0.3-0.7-0.80.5-0.0-0.70.20.6-0.3-0.3-0.40.91.1-0.70.7-1.00.50.5-0.4-0.40.4
Time in novel zone, NPP test0.50.51.5-0.1-0.1-0.5-0.60.40.3-0.60.40.5-0.5-0.6-0.71.01.2-1.01.0-1.20.80.8-0.7-0.70.7
Total zone transitions, NPP test1.82.64.9-1.91.91.41.6-1.62.01.22.2-1.5-2.2-1.8-1.8-0.1-0.1-2.22.2-1.31.21.2-1.1-1.11.1
Total locomotion distance, NPP test20.528.162.77.4-7.1-7.9-7.77.8-6.7-7.8-6.17.45.75.13.45.55.02.0-2.0-0.7-0.3-0.3-0.1-0.30.3
Locomotion velocity, NPP test20.028.362.37.5-7.1-7.9-7.77.7-6.8-7.7-6.27.55.85.23.55.44.82.2-2.2-0.5-0.4-0.4-0.1-0.30.3
Intraocular pressure7.911.122.8-4.74.84.14.2-4.04.63.54.5-3.8-4.4-4.0-3.7-1.2-1.0-2.92.9-1.81.61.6-1.3-1.01.0
Delta distance traveled before/after self-admin0.10.20.40.4-0.5-0.4-0.40.2-0.5-0.1-0.60.30.60.40.4-0.3-0.40.6-0.50.5-0.3-0.30.20.2-0.2
Delta ambulatory time before/after self-admin0.10.10.30.4-0.5-0.4-0.40.3-0.4-0.2-0.50.30.50.30.2-0.2-0.20.5-0.40.3-0.1-0.10.10.0-0.0
Parametrial fat weight0.51.12.5-1.31.41.21.1-1.61.21.20.8-0.5-0.7-1.2-0.9-0.6-0.7-0.80.8-0.31.21.2-1.1-1.01.0
Pavlov. Cond. lever latency0.91.22.71.4-1.3-1.6-1.51.7-1.2-1.6-1.11.51.00.90.41.51.60.2-0.2-0.20.00.0-0.2-0.20.2
Pavlov. Cond. magazine entry latency0.10.20.7-0.20.3-0.1-0.20.20.1-0.40.7-0.3-0.7-0.3-0.30.40.5-0.10.1-0.8-0.3-0.30.50.5-0.5
Pavlov. Cond. change in total contacts0.90.92.20.6-0.6-0.1-0.20.2-0.80.1-0.7-0.20.71.01.1-0.8-1.11.5-1.51.1-1.2-1.21.31.4-1.4
Pavlov. Cond. index score0.40.51.1-0.91.00.90.9-0.80.70.80.9-1.0-0.9-0.6-0.3-0.9-0.90.0-0.0-0.1-0.2-0.20.40.5-0.5
Pavlov. Cond. latency score0.40.51.1-1.01.00.90.9-0.90.80.81.0-1.0-0.9-0.6-0.4-0.8-0.8-0.10.1-0.2-0.2-0.20.40.5-0.5
Pavlov. Cond. lever contacts0.70.81.8-1.11.01.21.1-1.20.91.31.0-1.4-0.9-0.6-0.2-1.2-1.30.0-0.00.2-0.3-0.30.50.5-0.5
Pavlov. Cond. magazine entry number0.30.41.30.9-1.0-0.6-0.50.6-0.7-0.3-1.10.81.20.80.50.20.20.4-0.40.80.10.1-0.3-0.40.4
Pavlov. Cond. intertrial magazine entries0.10.10.30.1-0.50.30.10.1-0.00.4-0.1-0.30.10.30.4-0.2-0.20.1-0.10.5-0.3-0.30.20.2-0.2
Pavlov. Cond. lever-magazine prob. diff.0.40.61.4-0.80.91.00.9-0.80.50.90.7-1.1-0.6-0.30.1-1.2-1.20.4-0.40.3-0.5-0.50.70.7-0.7
Pavlov. Cond. response bias0.20.20.5-0.40.50.50.3-0.30.20.30.5-0.6-0.5-0.20.1-0.5-0.50.3-0.3-0.1-0.4-0.50.60.7-0.7
Pavlov. Cond. lever latency3.04.09.12.0-2.2-0.7-0.71.0-2.2-0.1-2.60.72.72.63.0-1.3-1.62.6-2.63.0-1.9-1.91.71.6-1.6
Pavlov. Cond. magazine entry latency0.80.92.3-1.21.20.60.4-0.61.20.21.4-0.6-1.5-1.3-1.50.30.6-1.11.1-1.40.70.7-0.6-0.60.6
Pavlov. Cond. change in total contacts1.21.74.6-1.11.20.10.2-0.31.3-0.41.6-0.2-1.7-1.6-2.11.31.7-1.51.5-2.11.21.2-1.0-1.01.0
Pavlov. Cond. index score2.32.96.7-1.91.90.80.7-1.01.90.22.3-0.7-2.4-2.3-2.60.91.2-2.22.2-2.51.61.5-1.3-1.31.3
Pavlov. Cond. latency score2.22.76.2-1.81.90.80.7-1.11.90.32.2-0.8-2.3-2.2-2.50.81.1-2.02.0-2.41.51.5-1.3-1.31.3
Pavlov. Cond. lever contacts2.73.77.9-2.22.21.00.9-1.42.30.52.7-1.2-2.8-2.5-2.80.71.1-2.52.5-2.61.61.6-1.4-1.31.3
Pavlov. Cond. magazine entry number2.22.65.52.1-2.2-1.4-1.31.5-2.1-0.9-2.21.12.22.32.3-0.0-0.31.7-1.71.7-1.4-1.41.11.1-1.1
Pavlov. Cond. intertrial magazine entries0.71.02.90.3-0.40.30.3-0.4-0.40.7-0.2-0.80.20.91.1-1.2-1.71.0-1.01.1-1.4-1.41.41.4-1.4
Pavlov. Cond. lever-magazine prob. diff.2.02.65.9-1.71.80.70.6-0.91.80.12.2-0.7-2.3-2.1-2.40.91.1-2.12.1-2.41.41.4-1.2-1.21.2
Pavlov. Cond. response bias2.83.89.1-2.32.31.01.0-1.22.30.42.9-1.4-3.0-2.5-2.90.81.1-2.52.5-2.81.41.4-1.1-1.01.0
Time in closed arm before self-admin0.50.52.00.9-0.9-1.4-1.20.9-0.8-1.2-0.41.00.30.40.10.90.90.1-0.0-0.7-0.1-0.10.10.0-0.0
Time in closed arm after self-admin0.20.20.4-0.40.60.30.5-0.10.50.10.5-0.1-0.5-0.6-0.40.40.5-0.60.6-0.50.40.4-0.5-0.50.5
Time in open arm before self-admin0.30.30.6-0.80.70.70.6-0.40.80.50.6-0.5-0.5-0.7-0.6-0.1-0.1-0.50.4-0.20.60.6-0.4-0.30.3
Time in open arm after self-admin0.30.40.9-0.90.70.90.8-0.90.81.00.5-0.8-0.5-0.5-0.4-0.9-0.9-0.10.10.30.00.00.10.0-0.0
Bone: periosteal estimation0.81.65.31.1-1.0-0.1-0.00.1-1.30.4-1.60.01.71.72.3-1.3-1.31.4-1.42.3-1.2-1.21.01.0-1.0
Bone: periosteal perimeter0.20.41.70.6-0.5-0.3-0.20.1-0.7-0.0-0.7-0.00.80.91.3-0.6-0.60.6-0.60.9-0.7-0.70.60.6-0.6
Bone: post-yield work0.30.41.4-0.50.60.91.2-1.00.41.10.0-0.70.1-0.10.5-0.8-1.1-0.20.21.0-0.1-0.10.00.1-0.1
Progressive ratio test 1 active lever presses1.01.13.2-0.10.2-0.2-0.40.60.4-0.80.60.6-0.7-0.8-0.91.81.7-1.41.4-1.51.21.2-1.2-1.11.1
Progressive ratio test 1 breakpoint0.90.92.8-0.10.2-0.2-0.40.60.4-0.80.50.6-0.6-0.7-0.81.71.6-1.31.3-1.41.21.2-1.1-1.01.0
Progressive ratio test 1 inactive lever presses0.50.52.8-0.00.2-0.1-0.10.70.3-0.70.70.1-0.8-0.4-0.51.71.6-0.90.9-1.10.40.4-0.2-0.30.3
Progressive ratio test 2 active lever presses0.60.72.70.1-0.1-0.5-0.90.50.2-0.80.80.3-1.0-0.5-0.71.61.6-1.01.0-1.60.30.3-0.2-0.10.1
Progressive ratio test 2 breakpoint0.50.62.30.3-0.3-0.7-1.10.5-0.0-0.90.70.4-0.8-0.3-0.61.51.4-0.80.8-1.50.20.2-0.1-0.00.0
Progressive ratio test 2 inactive lever presses1.01.23.6-0.60.60.1-0.3-0.10.8-0.51.4-0.1-1.5-1.2-1.11.61.5-1.61.7-1.90.90.9-0.8-0.70.7
Incentive Sensitization - Responses0.40.41.50.8-0.9-0.8-1.20.6-0.7-0.70.10.1-0.20.50.40.60.60.2-0.2-0.5-0.8-0.80.80.8-0.8
Incentive Sensitization - Breakpoint0.40.41.60.8-0.8-0.9-1.30.6-0.7-0.80.00.3-0.20.40.30.70.70.2-0.1-0.6-0.6-0.60.70.6-0.6
Sum of active levers in priming session hrs 5-64.14.010.51.9-1.6-2.7-2.62.6-1.5-3.0-1.53.21.40.4-0.13.23.0-0.30.4-1.61.41.4-1.7-1.71.7
Progressive ratio0.40.52.2-0.00.2-0.4-0.40.60.2-0.80.50.4-0.6-0.5-0.71.51.5-0.70.7-1.30.50.5-0.3-0.40.4
Food seeking constrained by brief footshock1.21.43.81.5-1.7-2.0-1.91.6-1.4-1.8-0.71.00.61.20.71.11.10.6-0.6-0.5-0.9-0.90.90.9-0.9
Seeking ratio, punishment vs. effort1.01.22.61.2-1.6-1.2-1.20.9-1.3-0.8-1.00.31.01.51.1-0.4-0.41.1-1.10.7-1.3-1.31.11.2-1.2
Retroperitoneal fat weight1.23.89.62.5-2.5-2.4-2.51.9-2.5-2.1-3.13.13.11.81.70.90.81.7-1.60.90.50.5-0.6-0.70.7
Reaction time number correct2.53.77.0-2.02.52.32.4-1.62.11.71.1-0.5-0.9-2.2-1.5-0.50.3-1.71.8-0.52.62.6-2.6-2.62.6
Reaction time mean minus median0.20.20.50.5-0.4-0.2-0.40.4-0.4-0.5-0.10.0-0.00.50.30.30.40.4-0.6-0.1-0.7-0.70.70.7-0.7
Reaction time mean minus median AUC0.20.31.1-0.10.40.0-0.20.30.2-0.60.30.3-0.4-0.4-0.51.01.1-0.50.4-0.80.60.6-0.6-0.70.7
Reaction time num false alarms7.810.621.04.6-4.6-4.5-4.44.2-4.3-4.1-3.73.43.53.92.92.51.92.5-2.40.8-1.9-1.91.71.6-1.6
Reaction time num false alarms AUC6.08.316.74.1-4.1-4.0-3.83.7-3.8-3.5-3.33.03.13.52.62.11.52.2-2.10.8-1.8-1.81.61.4-1.4
Reaction time trials correct on left2.53.77.0-2.02.52.32.4-1.62.11.71.1-0.5-0.9-2.2-1.5-0.50.3-1.71.8-0.52.62.6-2.6-2.62.6
Reaction time trials on left2.63.77.2-2.02.52.32.4-1.62.01.71.1-0.4-0.9-2.2-1.4-0.50.3-1.71.8-0.42.72.7-2.6-2.62.6
Reaction time mean1.31.83.41.8-1.7-1.8-1.61.6-1.8-1.6-1.71.51.71.51.20.70.81.2-1.30.6-0.7-0.70.60.6-0.6
Reaction time mean AUC0.91.22.51.5-1.4-1.3-1.21.3-1.5-1.2-1.61.31.61.31.20.40.61.1-1.20.8-0.5-0.50.40.4-0.4
Median of all reaction times1.92.64.92.2-2.1-2.1-1.91.9-2.2-1.7-2.21.82.21.91.60.60.71.5-1.61.0-0.8-0.80.60.7-0.7
Reaction time omissions0.20.30.60.5-0.3-0.4-0.30.2-0.6-0.4-0.70.50.80.50.8-0.1-0.3-0.10.10.40.60.6-0.7-0.80.8
Reaction time false alarm rate7.610.622.24.4-4.7-4.5-4.53.9-4.2-3.8-3.42.93.13.92.82.11.32.6-2.50.8-2.6-2.62.42.3-2.3
Reaction time premature initiation rate0.10.21.6-0.30.20.20.2-1.00.20.60.0-0.30.0-0.1-0.2-0.9-1.2-0.0-0.00.40.20.2-0.2-0.20.2
Reaction time premature initiations1.21.82.9-1.51.61.41.5-1.71.41.40.8-0.6-0.7-1.4-1.1-0.9-0.8-1.11.1-0.21.71.7-1.6-1.71.7
Std. dev. reaction times0.20.30.70.6-0.4-0.3-0.20.4-0.6-0.4-0.2-0.20.10.80.60.10.10.5-0.50.2-0.8-0.80.80.8-0.8
Reaction time trials completed2.63.77.2-2.02.52.32.4-1.62.01.71.1-0.4-0.9-2.2-1.4-0.50.3-1.71.8-0.42.72.7-2.6-2.62.6
Reaction time trials AUC2.23.26.8-1.82.32.12.2-1.41.81.50.8-0.2-0.6-2.0-1.3-0.40.3-1.51.6-0.32.62.6-2.5-2.62.6
Run reversals in cocaine runway, females0.30.31.10.10.1-0.4-0.30.70.0-0.80.20.5-0.2-0.2-0.41.01.0-0.60.6-0.90.30.3-0.2-0.20.2
Run reversals in cocaine runway, males4.13.96.9-1.92.21.21.1-1.42.10.61.9-0.2-1.9-2.6-2.60.90.9-2.52.5-2.12.52.5-2.4-2.42.4
Latency to leave start box in cocaine runway8.28.815.83.9-3.9-2.8-2.73.0-3.8-2.1-3.62.03.54.03.50.20.13.4-3.42.5-2.8-2.72.72.5-2.5
Latency to leave start box in cocaine runway, F4.65.09.52.7-2.7-1.6-1.51.9-2.7-1.1-2.51.02.53.12.7-0.4-0.42.7-2.72.2-2.5-2.52.52.3-2.3
Latency to leave start box in cocaine runway, M5.35.110.03.2-3.1-2.7-2.72.6-3.1-2.2-3.02.42.92.72.40.80.82.3-2.31.4-1.3-1.31.11.0-1.0
Std. dev. time between licks in bursts2.32.74.82.0-2.2-2.2-2.02.2-2.1-1.8-2.01.52.01.91.50.30.32.0-2.00.9-1.1-1.11.01.1-1.1
Total sessions with >9 infusions2.52.89.31.7-1.5-2.3-2.22.6-1.3-2.7-0.82.30.60.4-0.43.13.1-0.30.3-1.70.50.5-0.5-0.50.5
Short access day 1 total inactive lever presses0.30.30.6-0.40.60.30.2-0.20.50.00.6-0.1-0.7-0.7-0.80.70.7-0.80.8-0.80.70.7-0.6-0.50.5
Short access day 10 total inactive lever presses1.51.76.00.4-0.50.60.6-0.6-0.71.1-1.1-0.71.21.21.8-2.1-2.11.5-1.42.4-1.2-1.21.21.2-1.2
Short access day 1 total infusions3.73.911.72.1-1.9-2.9-2.92.9-1.7-3.3-1.22.80.90.7-0.13.43.4-0.20.2-1.90.60.6-0.6-0.60.6
Short access day 10 total infusions0.70.83.80.7-0.6-1.0-1.21.3-0.5-1.4-0.11.0-0.10.1-0.42.01.9-0.40.4-1.20.30.3-0.3-0.20.2
Short access total infusions2.12.48.01.5-1.4-2.1-2.22.2-1.1-2.5-0.82.20.60.3-0.32.82.8-0.40.4-1.60.70.7-0.8-0.70.7
Short access day 1 locomotion1.01.13.11.4-1.3-1.5-1.31.7-1.2-1.6-0.81.30.60.80.31.81.70.4-0.4-0.5-0.3-0.30.30.2-0.2
Short access day 10 total locomotion0.50.51.4-0.50.51.01.0-0.40.40.80.5-1.2-0.50.10.1-0.7-0.60.4-0.40.5-1.0-1.01.00.9-0.9
Short access total locomotion0.30.31.10.5-0.4-0.4-0.41.0-0.3-0.70.00.2-0.10.4-0.01.01.0-0.00.0-0.5-0.4-0.40.40.4-0.4
One hour access (0.3 mA shock)1.51.75.10.00.1-0.7-1.10.70.3-1.30.61.2-0.8-1.1-1.42.12.1-1.51.4-2.31.51.5-1.4-1.41.4
Compulsive drug intake0.20.20.6-0.30.40.60.5-0.80.30.70.3-0.4-0.3-0.3-0.1-0.7-0.7-0.40.30.1-0.0-0.00.00.1-0.1
One hour access (shock baseline)0.70.93.20.0-0.0-0.6-0.80.70.2-1.10.50.7-0.6-0.7-1.01.81.8-0.80.8-1.60.80.8-0.7-0.80.8
Social response proportion0.80.91.9-1.00.80.60.6-0.71.00.50.9-0.4-0.8-1.1-0.70.20.5-1.41.4-0.71.21.2-1.3-1.31.3
Social responses0.91.13.2-1.01.00.60.6-0.60.90.30.50.1-0.4-1.3-0.90.10.3-1.01.0-0.51.81.8-1.8-1.81.8
Social time2.12.78.31.8-1.7-0.6-0.51.1-1.9-0.2-2.71.02.82.12.3-1.2-1.12.1-2.12.9-0.9-0.90.50.5-0.5
Soleus weight0.10.31.10.7-0.5-0.7-0.61.0-0.6-0.9-0.40.70.30.4-0.00.80.60.3-0.3-0.3-0.1-0.10.10.1-0.1
Bone: stiffness0.71.13.21.3-1.4-0.7-0.80.3-1.3-0.3-1.40.51.41.51.8-0.3-0.81.3-1.31.4-0.9-0.90.70.6-0.6
Tibialis anterior weight0.20.72.10.9-0.4-0.5-0.61.0-0.7-0.8-1.21.51.20.30.30.90.9-0.00.00.21.01.0-1.1-1.11.1
Time to tail flick, vehicle, before self-admin1.81.84.3-1.82.02.12.0-1.71.81.81.6-1.6-1.6-1.4-1.1-0.8-0.9-1.11.1-0.40.60.6-0.4-0.40.4
Time to tail flick, vehicle, after self-admin3.03.27.4-2.52.22.42.3-2.72.22.52.1-2.6-2.0-1.7-1.2-2.1-2.1-1.11.00.00.30.3-0.10.0-0.0
Time to tail flick, test, before self-admin1.11.14.2-1.00.71.41.3-1.60.91.80.6-1.4-0.4-0.40.1-1.9-2.10.1-0.11.1-0.2-0.20.20.2-0.2
Time to tail flick, test, after self-admin2.93.06.6-2.32.32.32.4-2.62.22.42.0-2.1-1.9-1.7-1.1-1.5-1.9-1.21.2-0.20.60.6-0.4-0.50.5
Delta time to tail flick, vehicle, before/after SA0.50.51.6-0.90.70.90.9-1.10.81.10.6-1.0-0.5-0.5-0.2-1.3-1.2-0.30.20.40.10.1-0.1-0.10.1
Delta time to tail flick, test, before/after SA0.10.10.2-0.10.3-0.00.2-0.00.1-0.00.00.2-0.0-0.2-0.20.20.1-0.20.3-0.30.40.4-0.4-0.50.5
Tibia length0.30.83.0-0.81.41.61.7-1.30.71.70.2-0.9-0.0-0.40.3-1.4-1.0-0.10.11.10.20.2-0.1-0.00.0
Ambulatory time before self-admin1.11.12.31.5-1.4-1.1-1.21.3-1.4-1.1-1.21.01.11.31.00.50.61.0-1.00.4-0.9-0.90.80.8-0.8
Ambulatory time after self-admin2.12.34.32.0-1.9-1.3-1.41.4-1.9-0.8-1.91.11.92.11.6-0.1-0.51.8-1.81.4-1.5-1.51.31.2-1.2
Bone: tissue strength0.60.62.30.9-0.8-0.3-0.30.4-0.9-0.1-1.51.01.50.80.9-0.10.01.1-1.11.2-0.2-0.20.10.1-0.1
Total heroin consumption0.30.30.90.6-0.5-0.8-0.81.0-0.6-0.9-0.60.80.50.20.20.60.70.3-0.2-0.20.20.2-0.2-0.20.2
Bone: trabecular number1.01.63.41.3-1.3-0.5-0.50.9-1.3-0.2-1.60.61.61.51.7-0.5-1.01.8-1.81.6-1.3-1.31.11.1-1.1
Bone: trabecular spacing1.01.32.8-1.61.71.71.7-1.51.51.51.5-1.6-1.4-1.2-1.0-1.0-0.2-0.60.6-0.20.30.3-0.2-0.10.1
Bone: trabecular thickness0.30.41.60.5-0.4-0.8-0.70.9-0.3-1.00.10.7-0.20.0-0.41.30.8-0.50.5-1.00.20.2-0.2-0.20.2
Bone: trabecular tissue density0.50.72.0-0.61.10.20.5-0.10.7-0.21.2-0.5-1.4-0.7-1.21.01.4-0.70.7-1.40.30.3-0.2-0.20.2
Water consumed over 24 hours0.80.93.0-0.60.41.21.2-1.40.51.60.4-1.3-0.30.10.2-1.7-1.60.2-0.21.1-0.8-0.80.80.9-0.9
Number of responses in last shaping day0.10.10.40.4-0.3-0.10.10.3-0.4-0.1-0.50.20.60.40.60.20.20.5-0.50.6-0.1-0.10.00.1-0.1