Hub : Genes

Grm5

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Grm5 0.46 0.16 0.0e+00 0.25 0.27 0.3 0.3 3.2e-23 2.8e-25 5.4e-28 2.5e-28
2 IC isoform ratio XM_006229659.5 0.06 0.05 9.8e-03 0.02 0.02 0.03 0.03 5.6e-02 3.3e-02 2.4e-02 3.2e-02
3 NAcc gene expression Grm5 0.08 0.04 2.5e-10 0.08 0.07 0.07 0.07 7.3e-12 1.6e-10 8.2e-11 7.5e-11
4 NAcc mRNA stability Grm5 0.03 0.02 1.6e-04 0.03 0.02 0.02 0.02 3.3e-05 1.5e-04 1.8e-04 1.1e-04
5 Brain mRNA stability Grm5 0.1 0.06 4.3e-07 0.09 0.07 0.07 0.09 4.9e-09 6.4e-07 1.7e-07 8.0e-09
6 IC gene expression Grm5 0.3 0.13 4.4e-11 0.17 0.22 0.24 0.24 9.7e-08 8.0e-10 1.7e-10 1.2e-10
7 OFC gene expression Grm5 0.23 0.12 1.0e-04 0.05 0.16 0.16 0.13 2.7e-02 1.7e-04 1.0e-04 5.6e-04
8 PL gene expression Grm5 0.03 0.02 9.6e-04 0.01 0.02 0.01 0.02 8.9e-03 2.8e-03 7.1e-02 6.2e-03
9 PL intron excision ratio chr1_150723078_150733678 0.03 0.02 3.4e-03 0.01 0.02 0.01 0.01 3.0e-02 1.7e-03 1.1e-02 1.4e-02
10 pVTA mRNA stability Grm5 0.06 0.04 2.6e-03 0.01 0.03 0.02 0.01 7.6e-02 3.6e-03 1.3e-02 5.2e-02
11 IC mRNA stability Grm5 0.07 0.05 3.4e-03 0 0.04 0.02 0.03 2.0e-01 1.2e-02 6.6e-02 3.2e-02
12 PL isoform ratio XM_017588778.3 0.06 0.04 8.0e-06 0.05 0.05 0.04 0.04 4.3e-06 5.7e-06 4.2e-05 2.1e-05
13 BLA isoform ratio XM_017588780.3 0.08 0.06 4.1e-03 0.03 0.03 0 0.03 1.1e-02 9.5e-03 1.7e-01 1.4e-02
14 IC isoform ratio XM_017588778.3 0.08 0.05 3.1e-03 0.07 0.05 0.06 0.06 1.0e-03 4.4e-03 1.6e-03 1.7e-03
15 RMTg mRNA stability Grm5 0.22 0.12 2.3e-04 0.14 0.12 0.1 0.12 1.6e-04 4.0e-04 1.5e-03 6.0e-04
16 Brain isoform ratio XM_017588779.3 0.05 0.03 3.7e-04 0.02 0.02 0.03 0.02 1.1e-02 3.1e-03 7.1e-04 4.0e-03
17 NAcc isoform ratio XM_017588779.3 0.09 0.06 2.0e-11 0.07 0.08 0.07 0.08 2.0e-10 1.3e-11 2.9e-11 6.8e-12
18 IC isoform ratio XM_017588779.3 0.08 0.05 9.0e-03 0 0.04 0.02 0.01 2.3e-01 1.2e-02 5.0e-02 1.4e-01
19 NAcc isoform ratio XM_017588778.3 0.04 0.02 1.3e-06 0.01 0.04 0.03 0.03 3.8e-03 9.9e-07 1.7e-05 2.2e-05
20 OFC mRNA stability Grm5 0.15 0.1 9.1e-03 0.09 0.1 0.08 0.07 4.1e-03 2.5e-03 5.5e-03 8.0e-03
21 PL isoform ratio XM_017588779.3 0.07 0.04 8.7e-07 0.03 0.06 0.06 0.06 4.4e-04 2.3e-07 2.6e-07 1.2e-06
22 BLA isoform ratio XM_017588778.3 0.13 0.09 6.5e-04 0.01 0.04 0.03 0.02 1.4e-01 3.7e-03 8.8e-03 2.0e-02
23 Brain isoform ratio XM_017588778.3 0.07 0.04 2.1e-05 0.03 0.05 0.05 0.04 1.3e-03 1.0e-05 1.4e-05 4.5e-05
24 BLA isoform ratio XM_017588779.3 0.15 0.1 2.6e-04 0.01 0.05 0.02 0.04 9.5e-02 1.1e-03 2.7e-02 5.3e-03
25 LHb alternative TSS XM_017588779.3 0.23 0.13 3.4e-03 0.13 0.07 0.11 0.11 5.7e-04 9.1e-03 1.4e-03 1.5e-03
26 LHb alternative TSS XM_017588779.3 0.43 0.17 6.7e-04 0.2 0.17 0.12 0.18 2.0e-05 7.5e-05 8.8e-04 5.1e-05

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26
Bone: apparent density0.81.33.10.9-1.30.10.10.01.30.91.11.30.41.51.81.41.31.3-1.6-1.4-1.61.21.3-1.31.11.1-0.60.50.5
Area under the delay curve1.01.22.5-0.70.2-1.5-1.5-1.5-0.2-0.2-0.2-0.1-0.20.60.40.90.81.0-1.1-1.4-1.21.31.4-1.61.51.5-1.61.21.2
BMI with tail0.10.21.30.8-0.80.60.60.70.51.10.60.60.40.50.60.30.30.2-0.3-0.3-0.20.30.2-0.10.00.10.20.10.1
BMI without tail0.41.23.01.1-1.10.30.30.40.90.50.80.61.61.01.21.51.11.1-1.1-1.0-0.31.31.3-1.11.01.2-1.31.71.7
Body weight0.31.32.51.1-1.20.20.20.41.11.51.31.40.41.61.31.31.21.1-1.4-1.6-1.61.31.3-1.31.21.2-0.50.50.5
Weight adjusted by age0.40.61.20.8-0.90.60.60.71.10.81.01.10.71.00.90.80.91.1-0.6-0.6-0.60.60.6-0.40.30.40.00.60.6
Bone surface0.71.32.30.7-1.40.30.30.11.40.91.11.20.71.41.41.41.51.5-1.3-1.3-1.41.31.3-1.31.11.2-0.70.90.9
Bone volume0.61.12.10.8-1.30.20.20.11.30.81.11.20.61.41.51.31.41.2-1.3-1.2-1.41.21.2-1.21.01.0-0.60.60.6
Breakpoint value in progressive ratio session0.20.20.90.2-0.40.20.20.10.40.90.60.70.10.60.30.40.70.9-0.3-0.6-0.70.30.3-0.30.30.30.00.30.3
Number of licking bursts0.91.52.61.4-1.30.80.80.81.41.31.51.50.81.61.61.41.31.5-1.4-1.4-1.41.31.3-1.21.11.1-0.50.80.8
Context. condit. distance diff. score0.30.31.20.5-0.30.40.40.50.20.70.70.8-0.20.70.40.31.11.1-0.5-0.7-1.00.40.4-0.50.60.40.10.20.2
Locomotion velocity, session 18.99.621.4-4.44.2-4.5-4.5-4.6-4.1-4.2-4.5-4.2-3.5-3.3-2.8-2.5-3.5-3.51.31.81.1-1.4-1.20.6-0.5-0.6-0.8-1.6-1.6
Locomotion distance, session 10.30.40.9-0.50.5-0.4-0.4-0.7-0.4-0.6-0.6-0.7-0.3-0.7-0.9-0.5-1.0-0.90.80.70.6-0.5-0.50.5-0.5-0.40.2-0.5-0.5
Locomotion velocity, session 22.32.79.7-2.62.3-2.9-2.9-3.1-2.1-2.4-2.1-1.8-2.1-1.0-1.2-0.7-1.2-1.10.0-0.2-0.60.20.3-0.80.80.7-1.2-0.4-0.4
Locomotion distance, session 20.60.82.3-1.01.0-0.7-0.7-0.8-0.9-1.2-1.1-1.2-0.4-1.1-1.1-0.8-1.5-1.40.80.81.0-0.7-0.70.6-0.5-0.5-0.0-0.5-0.5
Locomotion velocity, session 31.11.34.3-1.71.6-2.0-2.0-2.1-1.5-1.9-1.4-1.3-1.0-0.6-0.9-0.3-0.3-0.20.0-0.3-0.20.30.4-0.70.70.7-1.20.50.5
Locomotion distance, session 33.53.812.5-3.02.8-3.2-3.2-3.2-2.7-3.5-2.6-2.4-1.9-1.2-1.0-0.6-1.1-1.0-0.4-0.3-0.40.50.6-1.11.31.2-2.00.40.4
Stereotopy head waving bouts, day 33.64.212.23.5-3.33.33.33.23.23.02.82.42.81.61.51.41.41.5-0.2-0.20.40.40.20.4-0.5-0.30.90.80.8
Stereotopy head waving duration, day 30.60.71.7-1.11.0-1.2-1.2-1.3-1.0-1.0-1.3-1.2-0.9-1.0-0.8-0.7-0.9-0.80.40.60.4-0.5-0.40.2-0.2-0.2-0.2-0.2-0.2
Locomotion velocity, session 72.42.67.9-2.42.2-2.1-2.1-2.0-2.2-2.8-2.5-2.5-1.2-1.7-1.4-1.0-2.0-1.90.30.60.9-0.3-0.3-0.00.20.2-1.2-0.1-0.1
Locomotion distance, session 72.02.56.8-2.42.6-2.1-2.1-1.9-2.5-1.9-2.2-2.0-2.4-1.6-1.1-1.5-1.7-1.60.20.50.0-0.7-0.60.20.0-0.2-0.2-1.1-1.1
Stereotopy head waving bouts, day 71.11.24.3-1.41.1-1.9-1.9-2.1-1.1-2.0-1.4-1.3-0.8-0.5-0.3-0.0-0.7-0.7-0.5-0.4-0.30.50.6-0.91.00.9-1.40.30.3
Stereotopy head waving duration, day 71.41.76.3-1.61.2-2.2-2.2-2.5-1.1-2.4-1.6-1.5-0.7-0.6-0.40.1-0.5-0.5-0.5-0.4-0.20.70.8-1.11.11.1-1.80.80.8
Locomotion velocity, session 83.03.69.8-3.12.9-3.0-3.0-3.1-2.8-2.5-2.6-2.2-2.8-1.6-1.8-1.5-1.2-1.20.60.5-0.3-0.6-0.4-0.10.20.0-0.5-0.7-0.7
Locomotion distance, session 80.20.31.00.8-0.61.01.00.90.60.60.80.70.50.60.20.30.60.7-0.2-0.4-0.30.30.2-0.20.20.20.10.30.3
Degree of sensitization distance1.11.14.31.3-1.01.81.81.90.92.11.11.00.40.20.2-0.40.10.10.50.50.4-0.8-0.91.0-1.1-1.11.6-0.9-0.9
Degree of sensitization stereotypy1.11.24.0-1.31.0-1.8-1.8-2.0-0.9-1.9-1.1-1.0-0.7-0.1-0.10.3-0.3-0.3-0.8-0.8-0.70.90.9-1.21.31.2-1.60.50.5
Conditioned locomotion1.31.53.80.2-0.31.01.00.9-0.10.9-0.1-0.30.2-1.0-1.0-1.1-1.0-1.11.61.61.7-1.6-1.71.9-1.9-1.81.6-1.1-1.1
Cocaine response after cond. corrected0.50.61.30.5-0.7-0.1-0.1-0.10.50.60.50.60.50.91.01.00.40.4-1.2-1.0-0.81.01.1-1.01.01.0-0.90.40.4
Cocaine response after cond. not corrected0.10.10.4-0.1-0.1-0.5-0.5-0.4-0.10.2-0.1-0.00.10.30.50.40.10.1-0.6-0.4-0.40.50.5-0.50.50.5-0.60.20.2
Cocaine response before conditioning0.10.10.50.10.00.20.20.40.10.10.20.10.1-0.0-0.0-0.10.70.70.20.20.2-0.2-0.20.3-0.3-0.30.30.40.4
Saline control response1.11.54.1-0.30.2-0.6-0.6-0.60.1-0.50.20.4-0.11.11.11.21.01.0-1.7-1.7-1.71.71.7-1.92.01.9-1.71.11.1
Bone: connectivity density1.42.14.91.2-1.70.40.40.41.61.41.51.70.71.92.21.71.81.7-2.0-1.7-1.91.61.6-1.51.41.4-0.70.80.8
Bone: cortical apparent density0.91.24.8-0.50.70.40.40.3-1.0-0.9-0.9-1.30.6-1.4-1.5-1.0-1.1-1.11.61.52.2-1.1-1.21.3-1.2-1.10.20.30.3
Bone: cortical area0.91.32.21.1-1.40.70.70.61.31.21.31.41.01.51.41.41.41.4-1.2-1.3-1.21.21.2-1.11.01.0-0.60.90.9
Bone: cortical porosity0.60.72.8-1.00.7-1.1-1.1-1.1-0.7-1.7-0.9-1.00.3-0.3-0.60.3-0.3-0.30.1-0.30.20.60.6-0.70.80.8-1.41.01.0
Bone: cortical porosity0.40.41.7-0.80.5-0.7-0.7-0.8-0.5-1.3-0.7-0.90.5-0.4-0.60.2-0.4-0.30.3-0.00.60.40.3-0.40.40.5-1.11.01.0
Bone: cortical thickness0.10.10.40.5-0.50.50.50.50.20.40.40.30.60.30.40.30.30.3-0.2-0.20.10.20.2-0.10.10.1-0.10.30.3
Bone: cortical thickness0.20.20.8-0.50.3-0.3-0.3-0.5-0.6-0.6-0.6-0.80.3-0.6-0.7-0.2-0.7-0.80.50.40.9-0.2-0.30.3-0.2-0.2-0.40.10.1
Bone: cortical tissue density0.91.24.9-0.50.70.40.40.4-1.1-0.9-0.9-1.30.6-1.4-1.6-1.0-1.1-1.11.71.52.2-1.2-1.31.4-1.2-1.10.30.30.3
Condit. Reinf. active minus inactive responses0.80.92.11.0-0.81.41.41.40.71.20.60.40.6-0.2-0.6-0.5-0.2-0.21.21.01.1-1.0-1.01.3-1.3-1.21.4-0.6-0.6
Condit. Reinf. active-inactive response ratio1.61.73.61.8-1.91.71.71.51.81.71.81.71.31.51.21.21.51.4-0.8-0.9-0.70.90.8-0.60.50.50.00.70.7
Condit. Reinf. active responses1.41.74.01.0-0.61.51.51.50.51.20.30.00.6-0.8-0.8-1.0-0.9-0.91.61.71.8-1.6-1.71.9-2.0-1.91.8-1.0-1.0
Condit. Reinf. inactive responses2.42.96.3-0.61.0-0.2-0.2-0.0-1.0-0.3-1.4-1.6-0.6-2.1-1.6-1.9-2.2-2.22.12.52.4-2.2-2.22.3-2.4-2.21.6-1.5-1.5
Incentive salience index mean0.40.51.40.3-0.20.50.50.50.10.80.10.0-0.1-0.5-0.7-0.7-0.4-0.41.00.90.8-1.0-1.01.1-1.2-1.11.2-0.8-0.8
Condit. Reinf. lever presses0.91.32.3-1.51.4-1.4-1.4-1.2-1.5-0.9-1.5-1.4-1.3-1.3-0.9-1.2-1.4-1.30.70.90.7-1.0-0.90.7-0.7-0.70.3-0.9-0.9
Condit. Reinf. active minus inactive responses1.31.74.0-1.11.2-0.2-0.2-0.3-1.3-1.0-1.4-1.6-0.3-1.8-1.9-1.5-1.2-1.31.91.72.0-1.5-1.51.5-1.4-1.40.6-0.3-0.3
Condit. Reinf. active-inactive response ratio3.54.17.8-1.41.5-0.2-0.2-0.2-1.6-0.7-1.7-1.9-1.1-2.5-2.5-2.5-1.9-2.02.82.82.6-2.6-2.62.6-2.6-2.51.8-1.4-1.4
Condit. Reinf. active responses0.70.92.5-0.91.0-0.3-0.3-0.5-1.0-1.0-1.1-1.3-0.3-1.3-1.6-1.0-0.8-0.91.41.21.4-1.0-1.01.0-0.8-0.80.2-0.0-0.0
Condit. Reinf. inactive responses0.91.22.60.3-0.5-0.1-0.1-0.10.70.00.60.60.61.20.91.31.11.1-1.2-1.5-1.21.51.5-1.51.61.6-1.41.21.2
Condit. Reinf. lever presses2.53.47.6-2.12.3-1.1-1.1-1.1-2.1-2.1-2.3-2.5-1.3-2.5-2.8-2.2-1.7-1.82.32.12.1-1.8-1.91.7-1.4-1.50.5-0.6-0.6
Condit. Reinf. lever reinforcers received0.50.82.1-0.91.0-0.3-0.3-0.5-1.0-0.9-1.0-1.1-0.5-1.2-1.5-1.0-0.7-0.71.31.01.1-0.9-0.90.9-0.7-0.80.3-0.2-0.2
Conditioned reinforcement - actives1.52.67.82.0-1.52.82.82.81.31.11.20.72.2-0.3-0.4-0.2-0.4-0.41.61.52.3-1.3-1.52.0-1.9-1.81.5-0.3-0.3
Conditioned reinforcement - inactives0.20.31.30.7-0.61.01.01.20.40.60.70.50.70.10.10.00.30.30.40.30.5-0.3-0.40.6-0.5-0.50.5-0.0-0.0
Conditioned locomotion1.52.04.90.30.11.21.21.1-0.30.0-0.2-0.50.4-1.3-1.4-1.3-1.3-1.32.02.02.2-1.9-2.02.2-2.2-2.11.8-1.0-1.0
Patch foraging indifference point 0 sec0.10.10.70.00.30.20.20.3-0.30.00.20.3-0.5-0.0-0.5-0.40.1-0.30.3-0.0-0.2-0.3-0.30.3-0.2-0.30.6-0.8-0.8
Patch foraging indifference point AUC0.50.81.70.1-0.2-0.5-0.5-0.40.30.20.30.4-0.00.90.90.91.00.9-1.3-1.2-1.21.21.2-1.31.31.3-1.00.90.9
Delay disc. indifference point, 0s delay2.52.74.91.9-2.21.31.31.22.11.81.91.82.01.91.72.01.81.9-1.4-1.5-1.01.61.5-1.31.21.3-0.91.51.5
Delay disc. indifference point, 16s delay1.01.12.9-1.51.2-1.7-1.7-1.7-1.3-1.6-1.3-1.4-0.3-0.6-0.8-0.0-0.2-0.1-0.1-0.50.20.60.6-0.80.91.0-1.61.01.0
Delay disc. indifference point, 2s delay0.70.82.7-0.3-0.4-0.9-0.9-1.00.41.00.40.7-0.41.00.70.91.01.0-1.0-1.3-1.61.01.1-1.31.11.1-0.70.30.3
Delay disc. indifference point, 24s delay0.91.02.5-1.20.9-1.6-1.6-1.5-1.0-1.5-1.0-1.0-0.1-0.2-0.40.30.10.3-0.4-0.7-0.20.80.8-1.01.11.1-1.61.21.2
Delay disc. indifference point, 4s delay3.73.96.61.2-1.9-0.0-0.0-0.11.81.41.71.81.22.42.12.42.52.6-2.1-2.5-2.22.42.5-2.42.22.3-1.72.12.1
Delay disc. indifference point, 8s delay0.40.52.4-1.00.6-1.5-1.5-1.5-0.6-0.7-0.7-0.5-0.8-0.1-0.10.0-0.10.1-0.4-0.3-0.60.30.4-0.60.50.5-0.60.30.3
Indifference point function ln k2.03.56.6-2.32.6-1.6-1.6-1.7-2.5-2.0-2.3-2.2-2.0-2.2-2.1-2.1-2.3-2.21.61.61.2-1.7-1.61.3-1.1-1.30.6-1.6-1.6
Indifference point function log k2.03.56.6-2.32.6-1.6-1.6-1.7-2.5-2.0-2.3-2.2-2.0-2.2-2.1-2.1-2.3-2.21.61.61.2-1.7-1.61.3-1.1-1.30.6-1.6-1.6
Patch foraging total patch changes 0 sec0.10.20.7-0.30.6-0.1-0.10.1-0.6-0.3-0.2-0.2-0.6-0.4-0.8-0.6-0.1-0.50.60.30.1-0.5-0.50.5-0.4-0.50.5-0.7-0.7
Patch foraging total patch changes 12 sec2.22.85.52.3-2.21.91.92.22.22.42.32.31.32.01.81.52.11.8-1.3-1.4-1.31.11.1-0.80.70.70.20.60.6
Patch foraging total patch changes 18 sec1.42.24.52.1-2.11.91.92.12.12.02.01.91.61.51.21.22.01.8-0.8-0.9-0.60.80.7-0.40.40.40.20.90.9
Patch foraging total patch changes 24 sec0.50.92.81.4-1.51.41.41.61.51.71.31.21.00.70.40.51.10.80.0-0.10.00.0-0.00.3-0.4-0.30.70.20.2
Patch foraging total patch changes 6 sec0.71.02.20.7-0.70.10.10.30.80.60.91.00.31.31.01.11.31.1-1.3-1.5-1.51.21.3-1.31.31.2-0.80.60.6
Patch foraging time to switch 0 sec5.210.622.04.3-4.73.43.43.54.63.44.13.84.23.73.63.73.53.4-2.5-2.5-1.52.62.5-1.91.61.9-0.92.52.5
Patch foraging water rate 0 sec2.75.813.3-3.53.7-2.7-2.7-2.8-3.7-2.5-3.0-2.6-3.4-2.5-2.9-2.7-2.1-2.31.91.40.6-1.8-1.71.1-0.9-1.20.7-1.9-1.9
Patch foraging water rate 12 sec7.415.429.7-5.25.5-4.1-4.1-4.3-5.3-3.7-5.1-4.7-5.0-4.6-4.4-4.5-4.4-4.13.13.22.0-3.3-3.12.4-2.1-2.41.2-3.0-3.0
Patch foraging water rate 18 sec13.020.143.1-6.66.5-5.6-5.6-5.8-6.2-4.7-6.0-5.4-6.2-5.0-4.7-4.8-4.5-4.13.03.01.5-3.3-3.02.0-1.8-2.10.9-3.0-3.0
Patch foraging water rate 24 sec3.85.316.8-3.33.2-2.9-2.9-3.0-3.0-1.6-2.7-2.1-4.1-2.2-2.2-2.6-2.0-1.81.51.4-0.2-1.8-1.61.0-1.0-1.31.3-2.4-2.4
Patch foraging water rate 6 sec5.17.514.5-3.73.8-3.0-3.0-3.1-3.8-2.6-3.5-3.2-3.7-3.1-2.9-3.1-3.0-3.02.02.11.1-2.2-2.11.5-1.3-1.60.9-2.4-2.4
Seeking ratio, delayed vs. immediate footshock0.10.20.7-0.50.6-0.8-0.8-0.7-0.4-0.5-0.3-0.1-0.40.0-0.20.10.20.40.0-0.3-0.40.20.2-0.30.20.3-0.20.40.4
Distance traveled before self-admin0.10.20.50.5-0.60.40.40.50.70.60.50.40.70.40.30.40.40.6-0.0-0.10.10.20.2-0.0-0.10.00.10.60.6
Distance traveled after self-admin1.62.04.61.6-1.91.11.11.22.11.41.71.71.51.71.71.71.61.7-1.2-1.2-1.01.21.3-1.00.80.9-0.41.31.3
Extensor digitorum longus weight0.00.20.80.2-0.60.20.20.10.60.90.40.5-0.10.40.50.20.1-0.5-0.3-0.2-0.50.10.2-0.20.00.00.3-0.6-0.6
Bone: elastic displacement0.50.61.2-0.50.6-0.2-0.2-0.1-0.50.3-0.5-0.4-1.0-0.8-0.8-1.1-0.7-0.71.00.90.4-1.1-1.01.0-1.0-1.01.1-1.1-1.1
Bone: elastic work0.20.30.8-0.20.2-0.1-0.1-0.2-0.3-0.1-0.3-0.3-0.4-0.5-0.4-0.5-0.9-0.90.50.70.4-0.6-0.60.6-0.6-0.60.6-0.9-0.9
Bone: endosteal estimation0.92.05.00.7-1.3-0.1-0.1-0.31.61.31.31.60.31.91.51.71.51.4-1.6-1.9-2.21.71.8-1.81.71.6-0.90.60.6
Bone: endosteal perimeter0.91.83.41.1-1.40.70.70.61.71.01.51.70.81.81.51.61.41.4-1.4-1.7-1.81.61.6-1.51.51.4-0.80.70.7
Epididymis fat weight0.30.92.81.4-1.21.11.11.21.11.71.41.50.21.11.20.60.71.1-0.7-0.7-1.00.30.3-0.20.10.10.7-0.2-0.2
Delta time in closed arm before/after self-admin0.80.82.9-1.31.1-1.7-1.7-1.7-1.1-1.1-1.1-0.9-1.4-0.4-0.4-0.4-0.4-0.6-0.1-0.2-0.60.10.2-0.50.40.4-0.5-0.3-0.3
Delta time in open arm before/after self-admin0.20.20.7-0.70.9-0.6-0.6-0.5-0.6-0.7-0.6-0.5-0.6-0.3-0.2-0.3-0.3-0.2-0.2-0.0-0.1-0.00.0-0.10.20.2-0.30.00.0
Diff in mean of infusions in LGA sessions0.91.02.8-0.4-0.4-1.0-1.0-1.10.20.30.40.7-0.11.10.71.21.20.9-1.1-1.5-1.71.31.4-1.51.41.4-1.10.50.5
Delay discount exponential model param1.01.12.30.7-0.21.51.51.50.10.10.20.00.3-0.6-0.4-0.9-0.8-1.01.01.31.3-1.3-1.31.5-1.5-1.51.4-1.1-1.1
Extinction: sum of active levers before priming0.70.72.1-0.20.30.20.20.2-0.20.4-0.2-0.1-0.7-0.7-0.9-1.1-0.7-0.71.21.00.7-1.2-1.21.2-1.3-1.31.5-1.1-1.1
Active lever presses in extinction session 61.11.12.70.4-0.21.01.00.90.00.9-0.0-0.20.3-0.9-0.9-1.0-0.9-0.61.41.41.5-1.4-1.51.6-1.6-1.61.4-0.8-0.8
Bone: final force1.01.63.71.1-1.30.40.40.21.51.21.51.70.41.81.61.51.41.2-1.6-1.6-1.91.41.5-1.51.31.3-0.50.20.2
Bone: final moment0.81.33.21.0-1.20.40.40.21.31.11.31.60.21.61.51.31.21.0-1.4-1.4-1.81.21.3-1.21.11.0-0.2-0.0-0.0
Food consumed during 24 hour testing period1.72.35.00.4-0.3-0.8-0.8-0.70.4-0.60.50.70.41.51.71.71.31.3-2.2-2.0-1.92.12.1-2.22.22.2-2.01.41.4
Glucose0.30.41.0-1.01.0-0.9-0.9-0.9-0.9-0.7-1.0-0.9-0.9-0.8-0.7-0.7-0.7-0.40.40.50.2-0.4-0.40.2-0.2-0.2-0.0-0.1-0.1
Heart weight2.33.55.5-1.92.0-0.9-0.9-1.1-2.2-1.6-2.0-1.9-1.9-2.2-2.2-2.3-2.3-2.32.02.01.5-2.1-2.01.8-1.7-1.81.3-1.8-1.8
Delay discount hyperbolic model param1.21.32.70.40.11.31.31.3-0.1-0.2-0.1-0.30.1-0.9-0.6-1.1-1.1-1.21.21.51.4-1.5-1.51.7-1.6-1.61.5-1.3-1.3
Intermittent access intake day 1-15 change1.02.14.4-0.60.90.30.30.4-1.0-0.1-0.7-0.7-0.8-1.5-1.6-1.8-1.3-1.02.02.01.5-2.1-2.12.1-2.0-2.11.8-1.5-1.5
Intermittent access intake escalation0.81.73.7-0.40.80.30.30.4-0.90.1-0.5-0.4-0.9-1.3-1.3-1.6-1.1-0.71.71.71.1-1.9-1.91.9-1.8-1.91.8-1.5-1.5
Intermittent access intake escalation 21.31.53.5-0.20.40.40.40.5-0.50.4-0.3-0.3-0.7-1.1-1.2-1.4-1.1-0.61.71.61.1-1.8-1.81.8-1.8-1.91.8-1.5-1.5
Intermitt. access day 1 inactive lever presses0.41.55.1-1.51.1-2.3-2.3-2.2-1.1-0.6-1.1-0.8-1.00.10.10.40.40.2-1.0-1.0-1.11.11.2-1.51.41.5-1.60.70.7
Intermitt. access day 15 inactive lever presses0.10.10.4-0.30.2-0.6-0.6-0.7-0.20.2-0.1-0.0-0.30.20.20.20.20.0-0.5-0.4-0.60.40.4-0.50.40.5-0.40.10.1
Intermitt. access escalation Index0.40.52.3-0.20.1-0.4-0.4-0.3-0.0-0.5-0.2-0.50.80.20.40.70.30.0-0.7-0.70.11.00.9-1.01.11.1-1.51.21.2
Intermittent access day 1 total infusions0.50.82.61.0-1.11.61.61.60.90.40.70.31.4-0.1-0.2-0.1-0.1-0.10.90.71.4-0.6-0.71.0-1.0-0.90.70.20.2
Intermittent access day 15 total infusions1.32.05.20.4-0.21.41.41.5-0.10.40.1-0.10.4-1.1-1.3-1.3-0.8-0.62.11.91.9-2.0-2.02.3-2.2-2.21.9-0.9-0.9
Intermittent access terminal intake (last 3 days)2.33.07.60.9-0.72.12.12.10.30.60.4-0.01.1-1.2-1.4-1.3-0.9-0.62.52.32.6-2.2-2.42.7-2.7-2.62.2-0.8-0.8
Intermittent access total infusions1.41.74.21.1-1.02.02.02.10.60.70.70.21.5-0.6-0.8-0.6-0.3-0.21.61.42.0-1.3-1.51.9-1.8-1.71.4-0.1-0.1
Intermittent access day 1 locomotion0.10.10.60.0-0.40.10.10.20.10.1-0.1-0.30.6-0.2-0.20.0-0.10.10.30.30.8-0.1-0.10.2-0.3-0.1-0.10.80.8
Intermittent access day 15 total locomotion1.22.23.5-1.31.3-0.9-0.9-0.8-1.5-0.8-1.4-1.3-1.3-1.8-1.7-1.8-1.7-1.51.91.81.4-1.9-1.81.7-1.7-1.71.3-1.4-1.4
Intermittent access total locomotion0.10.10.3-0.10.1-0.1-0.10.1-0.30.1-0.2-0.20.0-0.4-0.4-0.3-0.20.00.60.40.5-0.4-0.50.5-0.5-0.50.30.20.2
Intermittent access standard deviation0.61.23.91.4-1.02.02.01.90.80.91.00.90.8-0.0-0.3-0.40.10.21.10.91.0-1.0-1.11.4-1.4-1.41.6-0.4-0.4
Left kidney weight0.73.110.62.6-2.52.22.22.12.53.32.52.51.62.01.71.51.61.5-0.9-1.2-1.11.00.9-0.60.40.50.60.40.4
Right kidney weight0.62.96.52.0-1.91.11.11.01.92.52.32.50.82.32.01.82.12.2-1.6-1.9-2.21.61.6-1.41.21.2-0.10.80.8
Cocaine induced anxiety1.52.14.50.2-0.5-0.7-0.7-0.60.70.20.60.80.31.51.61.71.71.4-2.0-2.0-1.92.02.0-2.12.12.1-1.81.31.3
Post-drug Anxiety1.41.54.7-1.01.0-1.6-1.6-1.5-0.8-1.3-0.9-1.0-0.10.10.30.70.50.4-1.2-1.1-0.61.31.4-1.61.71.7-2.21.61.6
Baseline Anxiety5.66.415.7-3.53.6-3.0-3.0-3.0-3.6-3.5-3.8-4.0-2.0-3.2-2.8-2.4-2.8-2.61.71.92.2-1.5-1.51.0-0.8-0.8-0.7-0.2-0.2
Tail length0.51.84.20.1-0.3-0.9-0.9-0.90.3-0.60.30.30.91.10.91.61.31.5-1.4-1.6-1.01.81.8-1.81.81.9-2.02.02.0
Length with tail0.41.84.10.3-0.7-0.6-0.6-0.70.90.40.81.00.21.61.31.61.41.4-1.8-2.0-2.01.81.9-2.01.91.9-1.41.11.1
Length without tail0.20.63.4-0.1-0.3-0.4-0.4-0.40.50.90.50.9-1.20.90.60.30.50.4-0.9-1.1-1.90.60.7-0.90.80.60.2-0.7-0.7
Times rat made contact with spout0.50.61.50.3-0.3-0.5-0.5-0.50.2-0.60.00.00.60.50.91.00.50.5-1.1-0.7-0.51.01.1-1.01.01.1-1.21.01.0
Lifetime Intake1.82.25.11.4-1.22.22.22.30.91.10.80.51.4-0.6-0.8-0.7-0.4-0.31.81.62.1-1.6-1.72.1-2.1-2.01.8-0.5-0.5
Liver weight, left1.93.28.72.5-2.51.91.91.82.23.02.82.81.42.31.81.62.11.9-1.0-1.5-1.51.11.1-0.80.50.60.70.40.4
Liver weight, right1.93.36.81.6-2.10.90.90.82.02.02.22.21.52.31.62.12.62.4-1.4-2.2-1.81.91.9-1.71.51.6-0.81.61.6
Locomotor activity2.03.19.4-2.82.4-2.8-2.8-3.1-2.2-2.7-2.6-2.6-1.5-1.5-1.6-0.8-1.4-1.30.30.10.40.10.1-0.60.80.7-1.80.40.4
Locomotor testing distance1.52.77.6-2.42.3-2.0-2.0-2.3-2.1-2.8-2.5-2.6-1.1-1.8-1.8-1.2-1.9-1.70.90.81.1-0.5-0.50.20.10.0-1.10.10.1
Locomotor testing rearing0.91.84.5-2.01.9-1.4-1.4-1.4-1.7-2.1-2.0-2.1-1.2-1.7-1.6-1.3-1.7-1.60.90.91.0-0.7-0.70.5-0.3-0.4-0.5-0.4-0.4
Locomotion in novel chamber0.81.03.7-1.40.9-1.9-1.9-1.9-0.9-0.9-1.0-0.9-0.4-0.2-0.50.30.10.1-0.2-0.6-0.40.70.8-1.00.91.0-1.40.80.8
Locomotion in novel chamber post-restriction2.54.06.8-1.71.8-0.6-0.6-0.4-1.8-0.7-1.5-1.4-2.0-2.2-2.5-2.6-2.2-2.02.62.31.6-2.5-2.52.4-2.3-2.42.2-2.2-2.2
Fecal boli incidents, locomotor time 10.20.31.1-0.50.3-0.7-0.7-0.6-0.1-0.3-0.6-0.60.0-0.00.50.3-0.4-0.4-0.9-0.2-0.20.60.7-0.70.70.8-1.10.20.2
Change in fecal boli incidents, locomotor task0.10.10.20.3-0.00.50.50.4-0.10.10.20.10.3-0.1-0.3-0.10.30.20.40.10.4-0.2-0.30.3-0.3-0.30.20.30.3
Time >=10cm from walls, locomotor time 11.51.62.81.3-1.51.01.00.91.40.41.21.11.71.31.61.61.31.3-1.4-1.1-0.61.31.3-1.11.11.1-1.21.51.5
Bouts of movement, locomotor time 10.50.61.5-1.10.9-1.2-1.2-1.2-0.8-1.0-1.2-1.1-1.0-0.6-0.2-0.4-0.7-0.9-0.20.1-0.10.00.1-0.30.40.3-0.7-0.5-0.5
Total resting periods, locomotor time 10.60.61.5-1.10.9-1.1-1.1-1.1-0.8-0.8-1.2-1.1-1.2-0.8-0.3-0.7-1.0-1.10.00.5-0.0-0.4-0.30.00.0-0.1-0.2-0.8-0.8
Rest time, locomotor task time 10.30.42.7-0.80.6-0.6-0.6-0.5-0.50.3-0.6-0.3-1.7-0.4-0.1-0.8-0.3-0.50.00.3-0.6-0.5-0.40.2-0.2-0.40.7-1.0-1.0
Distance moved, locomotor task time 10.10.10.40.5-0.40.20.20.20.30.10.50.50.60.2-0.20.30.10.20.4-0.00.2-0.1-0.10.2-0.3-0.20.3-0.0-0.0
Vertical activity count, locomotor time 10.61.43.01.7-1.71.31.31.11.71.11.71.61.61.41.31.41.01.3-0.7-0.8-0.60.90.8-0.60.40.5-0.10.80.8
Time >=10cm from walls, locomotor time 22.33.46.31.6-1.51.01.00.91.3-0.21.31.02.51.81.82.41.91.9-2.0-2.0-0.82.32.1-2.02.22.2-2.52.52.5
Bouts of movement, locomotor time 20.30.51.5-0.90.8-1.2-1.2-1.1-0.6-1.2-0.7-0.7-0.2-0.1-0.20.20.3-0.2-0.3-0.5-0.20.60.6-0.80.90.9-1.20.50.5
Total resting periods, locomotor time 20.20.41.1-0.80.7-1.0-1.0-1.0-0.5-1.0-0.7-0.8-0.1-0.3-0.30.10.3-0.3-0.1-0.30.00.50.5-0.60.60.7-1.10.50.5
Rest time, locomotor task time 20.40.62.60.9-1.00.90.91.01.11.61.01.00.40.40.30.10.50.50.30.30.0-0.4-0.40.6-0.8-0.71.1-0.3-0.3
Distance moved, locomotor task time 20.60.71.71.2-1.10.90.90.81.01.01.31.30.61.20.90.90.60.5-0.7-0.9-0.90.70.7-0.60.50.50.00.00.0
Vertical activity count, locomotor time 22.83.88.42.9-2.62.62.62.52.62.02.62.52.22.32.52.01.71.5-1.8-1.5-1.11.51.4-1.11.01.1-0.30.80.8
Light reinforcement 13.58.724.84.8-4.44.64.64.64.25.04.34.32.52.92.71.82.21.9-1.0-1.0-1.10.50.40.2-0.4-0.42.0-0.7-0.7
Light reinforcement 27.110.931.25.4-4.85.55.55.64.65.34.84.63.22.92.51.72.01.7-0.5-0.6-0.50.2-0.00.8-1.0-1.02.6-1.0-1.0
Bone: marrow area0.92.04.70.7-1.4-0.0-0.0-0.21.61.31.31.60.41.91.51.71.41.4-1.6-1.9-2.21.71.8-1.81.71.6-0.90.60.6
Bone: maximum diameter0.40.81.50.6-1.00.40.40.21.01.01.01.10.61.20.91.11.01.0-0.8-1.2-1.11.11.1-1.01.01.0-0.50.60.6
Bone: maximum force0.61.02.70.7-1.00.10.1-0.01.10.91.11.30.21.41.41.20.90.7-1.3-1.3-1.71.11.2-1.21.11.0-0.4-0.1-0.1
Bone: maximum moment0.40.72.30.6-0.90.10.1-0.11.00.90.91.2-0.01.21.21.00.70.5-1.2-1.1-1.50.91.0-1.00.80.8-0.2-0.3-0.3
Mean time between licks in bursts1.02.59.52.3-1.93.13.13.11.62.51.61.21.90.40.40.10.40.70.60.71.3-0.6-0.81.2-1.1-1.11.30.30.3
Mean num. licks in bursts0.81.23.2-1.41.3-1.3-1.3-1.3-1.4-1.8-1.6-1.7-0.6-1.4-1.2-0.9-1.1-1.40.81.01.2-0.8-0.70.6-0.6-0.5-0.3-0.3-0.3
Cd content in liver0.80.93.51.5-1.31.91.91.81.31.01.20.91.30.50.20.40.50.70.20.10.5-0.0-0.20.4-0.4-0.30.50.40.4
Co content in liver0.60.73.10.1-0.30.10.10.10.2-1.4-0.4-0.81.7-0.2-0.00.70.1-0.3-0.20.01.20.60.5-0.40.50.7-1.61.61.6
Cu content in liver2.53.07.70.2-0.6-0.8-0.8-0.60.6-1.00.30.21.51.31.52.11.81.7-2.1-2.0-1.12.32.3-2.32.32.4-2.82.72.7
Fe content in liver0.20.30.90.7-0.71.01.00.90.60.60.80.70.70.50.00.30.50.50.3-0.10.10.10.00.1-0.1-0.10.30.20.2
K content in liver0.50.51.40.8-0.90.30.30.60.71.20.80.90.50.81.10.70.81.0-0.7-0.6-0.60.50.5-0.40.30.30.00.30.3
Mg content in liver1.41.53.0-0.0-0.3-1.0-1.0-0.80.3-0.00.40.60.11.21.31.31.41.5-1.6-1.6-1.61.51.6-1.71.61.7-1.41.31.3
Mn content in liver0.00.00.2-0.10.1-0.2-0.2-0.1-0.10.20.00.1-0.3-0.0-0.1-0.10.10.50.10.1-0.2-0.2-0.20.2-0.2-0.20.4-0.2-0.2
Na content in liver3.43.78.7-0.5-0.0-1.9-1.9-1.90.1-0.40.30.7-0.41.81.61.91.51.6-2.5-2.7-2.92.52.7-2.92.82.8-2.41.31.3
Rb content in liver1.41.63.71.0-1.30.50.50.51.41.41.51.70.51.81.31.41.91.5-1.3-1.6-1.81.41.4-1.31.21.2-0.40.50.5
Se content in liver1.41.62.80.9-1.2-0.1-0.10.11.21.01.11.21.01.51.61.71.51.4-1.6-1.5-1.41.61.6-1.51.41.5-1.11.21.2
Sr content in liver0.90.73.6-1.20.8-1.1-1.1-1.5-0.8-1.9-1.1-1.20.0-0.6-0.90.0-0.4-0.40.2-0.00.40.30.3-0.40.60.6-1.30.90.9
Zn content in liver0.30.41.00.3-0.40.10.10.20.20.00.50.40.50.60.70.71.01.0-0.7-0.7-0.50.70.7-0.70.70.7-0.60.90.9
Bone: minimum diameter2.95.39.12.4-2.61.41.41.42.52.22.52.61.92.93.02.82.62.6-2.7-2.5-2.32.52.5-2.32.22.2-1.31.71.7
Time in familiar zone, hab. session 10.10.10.50.4-0.50.40.40.50.40.70.40.5-0.20.20.5-0.0-0.00.0-0.20.0-0.3-0.1-0.10.1-0.2-0.20.5-0.5-0.5
Time in novel zone, hab. session 10.00.00.2-0.20.2-0.1-0.1-0.3-0.2-0.3-0.1-0.20.2-0.0-0.50.10.10.00.2-0.20.10.20.1-0.10.20.2-0.40.30.3
Total zone transitions, hab. session 12.13.010.8-2.62.3-2.9-2.9-3.3-2.2-2.2-2.3-1.9-2.5-1.3-1.4-1.1-1.6-1.50.40.3-0.4-0.4-0.2-0.30.20.1-0.5-1.0-1.0
Total locomotion distance, hab. session 112.617.847.36.8-6.46.86.86.66.26.96.15.74.73.83.22.73.03.1-0.8-1.1-0.40.80.50.6-0.9-0.72.50.30.3
Locomotion velocity, hab. session 112.617.848.36.8-6.46.96.96.76.26.86.15.64.93.63.02.62.93.0-0.4-0.7-0.10.50.20.9-1.2-0.92.70.30.3
Time in familiar zone, hab. session 20.40.50.90.7-0.70.50.50.40.70.70.80.90.10.90.90.70.80.8-1.0-0.8-1.00.60.6-0.60.60.5-0.10.10.1
Time in novel zone, hab. session 21.41.54.1-1.01.0-0.5-0.5-0.5-1.1-1.5-1.5-1.80.1-1.6-1.6-1.1-1.6-1.61.51.52.0-1.1-1.21.2-1.1-0.90.0-0.1-0.1
Total zone transitions, hab. session 21.31.74.6-1.71.6-1.8-1.8-2.1-1.5-2.1-1.9-1.9-1.1-1.3-1.3-0.8-1.8-1.70.50.60.6-0.3-0.30.00.00.0-0.8-0.4-0.4
Total locomotion distance, hab. session 215.320.054.77.4-6.87.47.47.16.67.06.35.75.53.93.22.93.03.1-0.6-0.80.00.80.40.7-1.0-0.72.50.60.6
Locomotion velocity, hab. session 214.419.251.87.2-6.67.17.16.86.57.16.35.85.13.83.12.83.13.1-0.5-0.8-0.20.70.40.7-1.1-0.82.60.40.4
Novel to familiar place preference ratio0.30.31.10.7-0.50.80.81.10.40.60.30.10.7-0.20.1-0.2-0.2-0.20.40.50.8-0.4-0.50.7-0.6-0.60.5-0.2-0.2
Novelty place preference0.30.41.00.4-0.10.60.60.80.10.4-0.0-0.20.3-0.5-0.3-0.5-0.5-0.50.70.81.0-0.8-0.80.9-0.9-0.80.7-0.4-0.4
Time in novel zone, NPP test0.50.61.30.10.20.40.40.6-0.20.2-0.3-0.4-0.0-0.8-0.6-0.8-0.9-0.90.91.01.1-1.0-1.11.1-1.1-1.10.9-0.8-0.8
Total zone transitions, NPP test1.82.66.7-1.81.9-1.4-1.4-1.6-1.8-2.2-2.2-2.3-1.1-2.0-1.8-1.5-2.6-2.51.21.51.5-1.2-1.10.9-0.8-0.8-0.1-1.1-1.1
Total locomotion distance, NPP test15.320.963.97.5-6.88.08.07.86.67.16.45.75.53.42.82.32.22.30.1-0.10.80.0-0.31.6-1.9-1.63.3-0.2-0.2
Locomotion velocity, NPP test15.021.163.47.5-6.88.08.07.76.77.26.55.85.53.62.92.42.42.5-0.0-0.30.60.1-0.21.4-1.8-1.53.2-0.1-0.1
Intraocular pressure6.59.421.4-4.54.3-3.9-3.9-4.0-4.1-4.6-4.3-4.3-3.1-3.5-3.7-2.8-3.0-2.92.22.01.8-1.8-1.71.1-0.9-1.0-0.5-0.9-0.9
Delta distance traveled before/after self-admin0.90.91.41.1-1.10.90.90.91.20.61.11.10.81.21.21.01.11.0-1.0-1.0-1.00.90.9-0.80.90.8-0.50.50.5
Delta ambulatory time before/after self-admin0.70.91.81.2-1.21.11.11.11.30.71.21.20.81.11.11.01.11.0-0.9-0.9-0.80.80.7-0.70.70.6-0.30.40.4
Parametrial fat weight0.92.05.3-1.71.9-1.4-1.4-1.3-2.0-0.9-1.6-1.4-2.3-1.5-1.4-1.8-1.3-1.41.11.20.3-1.4-1.31.0-0.9-1.11.0-1.5-1.5
Pavlov. Cond. lever latency0.70.82.71.5-1.41.71.71.51.41.31.11.01.00.50.40.30.20.20.20.20.3-0.2-0.30.5-0.6-0.50.8-0.2-0.2
Pavlov. Cond. magazine entry latency0.20.31.0-0.60.5-0.2-0.2-0.0-0.7-0.7-0.5-0.80.4-0.6-0.8-0.3-0.2-0.20.70.41.0-0.2-0.30.3-0.2-0.2-0.40.50.5
Pavlov. Cond. change in total contacts0.90.91.90.4-0.70.00.00.10.60.40.70.80.61.10.91.11.31.4-1.0-1.2-1.01.21.2-1.21.11.2-1.01.21.2
Pavlov. Cond. index score0.30.41.2-1.10.9-1.0-1.0-0.8-1.1-0.9-0.8-0.8-0.4-0.5-0.6-0.2-0.1-0.10.1-0.10.10.10.1-0.20.30.3-0.60.30.3
Pavlov. Cond. latency score0.30.41.2-1.10.9-1.0-1.0-0.8-1.0-0.9-0.8-0.8-0.4-0.5-0.6-0.3-0.2-0.20.20.00.20.00.0-0.20.20.2-0.60.30.3
Pavlov. Cond. lever contacts0.40.41.0-0.80.7-1.0-1.0-0.8-0.8-0.9-0.6-0.6-0.3-0.10.10.20.20.2-0.6-0.5-0.40.50.5-0.70.80.8-1.00.60.6
Pavlov. Cond. magazine entry number0.30.41.21.0-0.80.50.50.41.10.90.81.00.00.81.10.50.40.4-0.7-0.3-0.80.30.4-0.30.20.20.4-0.3-0.3
Pavlov. Cond. intertrial magazine entries0.20.21.00.5-0.3-0.3-0.3-0.10.40.20.10.10.20.41.00.50.20.2-1.0-0.4-0.50.50.6-0.60.50.6-0.50.30.3
Pavlov. Cond. lever-magazine prob. diff.0.30.40.9-0.90.7-1.0-1.0-0.8-0.8-0.7-0.5-0.4-0.2-0.0-0.20.20.30.3-0.3-0.6-0.40.60.5-0.70.80.7-1.00.60.6
Pavlov. Cond. response bias0.10.10.3-0.40.3-0.3-0.3-0.2-0.5-0.4-0.2-0.30.2-0.0-0.30.10.30.30.0-0.30.10.30.2-0.30.30.3-0.60.60.6
Pavlov. Cond. lever latency3.44.610.12.2-2.30.80.80.82.22.42.42.71.12.93.22.52.32.3-2.8-2.5-2.82.32.4-2.22.02.0-0.80.90.9
Pavlov. Cond. magazine entry latency0.91.12.0-1.31.4-0.6-0.6-0.5-1.4-1.3-1.3-1.4-0.8-1.4-1.4-1.3-0.9-1.01.11.01.1-1.0-1.00.9-0.8-0.80.3-0.5-0.5
Pavlov. Cond. change in total contacts1.11.74.1-1.01.00.10.1-0.0-1.1-1.1-1.2-1.5-0.3-1.7-2.0-1.5-1.0-1.22.01.72.0-1.6-1.71.7-1.5-1.50.8-0.4-0.4
Pavlov. Cond. index score2.43.36.7-1.92.0-0.8-0.8-0.8-2.0-1.9-2.1-2.3-1.1-2.4-2.6-2.2-1.7-1.92.32.12.2-1.9-2.01.8-1.6-1.70.8-0.8-0.8
Pavlov. Cond. latency score2.23.06.1-1.92.0-0.8-0.8-0.8-2.0-1.9-2.0-2.2-1.2-2.3-2.5-2.1-1.6-1.72.11.92.0-1.8-1.91.7-1.5-1.50.7-0.7-0.7
Pavlov. Cond. lever contacts3.24.49.0-2.22.3-0.8-0.8-0.9-2.2-2.3-2.4-2.6-1.2-2.8-3.0-2.5-2.3-2.42.72.42.6-2.2-2.32.1-1.9-1.90.8-1.0-1.0
Pavlov. Cond. magazine entry number2.43.05.82.4-2.41.51.51.52.42.12.22.21.82.22.32.01.51.6-1.8-1.5-1.31.51.5-1.21.11.2-0.50.80.8
Pavlov. Cond. intertrial magazine entries0.60.92.10.4-0.4-0.3-0.3-0.20.5-0.00.30.20.90.80.81.20.90.9-1.1-1.0-0.61.31.3-1.21.21.3-1.41.41.4
Pavlov. Cond. lever-magazine prob. diff.2.33.06.1-1.91.9-0.7-0.7-0.8-2.0-1.8-2.0-2.2-1.0-2.3-2.5-2.1-1.7-1.82.22.02.1-1.9-1.91.8-1.6-1.60.7-0.7-0.7
Pavlov. Cond. response bias3.24.49.1-2.22.3-0.8-0.8-0.9-2.3-2.4-2.5-2.8-1.0-2.8-3.0-2.4-2.2-2.32.72.42.7-2.1-2.22.1-1.8-1.80.6-0.8-0.8
Time in closed arm before self-admin0.10.20.80.7-0.40.90.90.80.40.10.40.30.80.10.10.20.20.30.10.10.5-0.1-0.20.3-0.2-0.20.10.20.2
Time in closed arm after self-admin0.10.10.20.0-0.2-0.0-0.0-0.10.10.2-0.1-0.10.1-0.2-0.3-0.1-0.3-0.40.50.40.4-0.3-0.30.4-0.4-0.40.2-0.4-0.4
Time in open arm before self-admin0.00.00.1-0.0-0.1-0.1-0.1-0.1-0.00.3-0.1-0.0-0.20.10.00.00.00.1-0.1-0.1-0.20.10.1-0.20.10.2-0.10.10.1
Time in open arm after self-admin0.40.41.3-0.90.7-1.1-1.1-1.1-0.6-0.3-0.6-0.3-1.1-0.00.2-0.1-0.00.1-0.6-0.4-0.90.40.5-0.70.60.6-0.40.10.1
Bone: periosteal estimation1.53.15.81.1-1.70.30.30.11.91.51.72.00.92.32.12.21.91.8-2.1-2.3-2.42.22.2-2.22.02.0-1.21.11.1
Bone: periosteal perimeter0.50.81.40.6-0.80.40.40.40.80.60.91.00.61.20.91.10.90.9-1.0-1.2-1.11.11.1-1.11.11.1-0.70.70.7
Bone: post-yield work0.30.51.7-0.70.4-1.1-1.1-1.3-0.4-0.5-0.20.0-0.70.40.40.40.30.0-0.7-0.8-1.20.70.8-1.00.90.9-0.7-0.1-0.1
Progressive ratio test 1 active lever presses0.91.22.8-0.0-0.00.50.50.5-0.30.1-0.4-0.60.1-1.1-1.1-1.1-1.1-1.21.61.51.7-1.4-1.51.6-1.6-1.61.2-0.9-0.9
Progressive ratio test 1 breakpoint1.01.22.8-0.10.00.40.40.5-0.30.1-0.4-0.60.1-1.1-1.1-1.1-1.1-1.21.61.51.7-1.5-1.51.6-1.7-1.61.2-0.9-0.9
Progressive ratio test 1 inactive lever presses0.10.10.3-0.3-0.2-0.2-0.2-0.2-0.10.4-0.3-0.40.1-0.4-0.3-0.2-0.3-0.40.30.30.5-0.2-0.20.3-0.3-0.2-0.1-0.1-0.1
Progressive ratio test 2 active lever presses0.30.41.80.2-0.20.60.60.7-0.00.0-0.1-0.30.9-0.6-0.6-0.3-0.4-0.41.00.81.3-0.7-0.70.9-0.8-0.80.30.10.1
Progressive ratio test 2 breakpoint0.30.41.90.2-0.20.50.50.6-0.00.0-0.1-0.40.8-0.6-0.7-0.3-0.4-0.41.00.91.4-0.7-0.81.0-0.9-0.80.30.10.1
Progressive ratio test 2 inactive lever presses0.81.23.1-0.40.30.40.40.5-0.60.2-0.6-0.80.2-1.3-1.3-1.1-1.1-1.21.61.51.8-1.4-1.51.6-1.5-1.50.9-1.0-1.0
Incentive Sensitization - Responses0.20.31.40.5-0.60.30.30.40.50.10.40.31.20.40.50.80.60.6-0.3-0.40.10.60.6-0.40.50.5-0.90.80.8
Incentive Sensitization - Breakpoint0.20.31.40.5-0.60.40.40.60.60.20.50.31.20.40.40.70.60.6-0.2-0.30.20.40.4-0.30.40.4-0.70.70.7
Sum of active levers in priming session hrs 5-63.23.08.00.9-0.72.02.01.90.61.90.70.50.2-0.8-1.1-1.4-0.9-0.92.01.91.7-2.2-2.32.6-2.6-2.62.8-1.8-1.8
Progressive ratio0.50.72.90.1-0.20.60.60.7-0.0-0.3-0.2-0.50.7-0.9-1.0-0.6-0.6-0.31.41.21.7-1.0-1.11.3-1.3-1.20.70.20.2
Food seeking constrained by brief footshock0.70.94.11.5-1.11.91.91.81.00.31.00.52.00.40.50.60.40.40.10.21.10.1-0.10.4-0.3-0.2-0.10.80.8
Seeking ratio, punishment vs. effort1.21.73.31.7-1.31.31.31.21.50.91.51.31.51.51.81.51.31.0-1.6-1.2-0.81.41.3-1.11.21.2-0.80.90.9
Retroperitoneal fat weight0.41.94.71.6-1.51.11.11.21.42.21.92.10.31.81.51.11.81.9-1.2-1.6-1.81.01.0-0.90.80.70.40.30.3
Reaction time number correct1.83.611.4-2.41.9-2.4-2.4-2.4-1.9-0.1-1.8-1.2-3.4-1.6-1.8-2.1-1.7-1.71.41.2-0.2-1.7-1.51.1-1.3-1.41.7-2.6-2.6
Reaction time mean minus median0.10.21.20.2-0.50.30.30.40.4-0.30.2-0.11.10.10.20.50.10.4-0.1-0.10.50.30.3-0.10.10.3-0.61.01.0
Reaction time mean minus median AUC0.10.40.9-0.60.30.00.00.2-0.4-0.7-0.4-0.50.0-0.7-0.9-0.6-0.8-0.60.90.71.0-0.8-0.80.8-0.8-0.80.4-0.4-0.4
Reaction time num false alarms6.59.222.54.7-4.54.54.54.44.14.14.13.74.23.02.82.82.72.5-1.4-1.4-0.41.51.3-0.60.40.60.21.71.7
Reaction time num false alarms AUC4.67.318.14.2-3.93.93.93.83.63.73.73.33.82.72.62.52.52.2-1.3-1.3-0.41.41.2-0.60.40.60.21.51.5
Reaction time trials correct on left1.83.611.4-2.41.9-2.4-2.4-2.4-1.9-0.1-1.8-1.2-3.4-1.6-1.8-2.1-1.7-1.71.41.2-0.2-1.7-1.51.1-1.3-1.41.7-2.6-2.6
Reaction time trials on left1.93.511.4-2.41.9-2.3-2.3-2.4-1.9-0.0-1.7-1.2-3.4-1.6-1.8-2.1-1.8-1.71.41.2-0.3-1.7-1.51.1-1.3-1.41.7-2.7-2.7
Reaction time mean0.91.43.01.5-1.61.71.71.61.41.31.71.51.51.31.11.11.21.6-0.6-0.8-0.50.70.6-0.40.40.40.01.01.0
Reaction time mean AUC0.71.12.31.2-1.31.31.31.21.21.11.51.41.01.21.11.01.21.5-0.7-0.9-0.70.70.7-0.50.50.5-0.00.80.8
Median of all reaction times1.52.24.51.9-1.92.02.01.91.71.82.12.11.51.71.51.31.62.0-0.9-1.1-0.90.90.8-0.60.60.60.10.90.9
Reaction time omissions0.30.41.10.6-0.90.60.60.50.50.91.01.10.41.00.70.70.30.6-0.7-0.9-0.80.60.6-0.60.50.5-0.0-0.0-0.0
Reaction time false alarm rate6.89.422.74.8-4.24.54.54.53.93.24.03.44.73.03.03.12.92.6-1.7-1.6-0.21.91.6-0.90.91.1-0.52.42.4
Reaction time premature initiation rate0.00.00.2-0.20.4-0.2-0.2-0.3-0.1-0.1-0.2-0.1-0.40.00.0-0.0-0.0-0.0-0.2-0.2-0.40.10.2-0.30.30.2-0.2-0.0-0.0
Reaction time premature initiations0.71.34.4-1.61.4-1.5-1.5-1.5-1.2-0.2-1.2-0.9-2.1-1.0-1.1-1.3-1.1-1.00.70.6-0.2-0.9-0.80.5-0.5-0.60.8-1.4-1.4
Std. dev. reaction times0.20.51.90.2-0.40.30.30.20.3-0.40.30.01.30.40.40.90.30.7-0.4-0.50.20.70.7-0.60.60.7-1.11.41.4
Reaction time trials completed1.93.511.4-2.41.9-2.3-2.3-2.4-1.9-0.0-1.7-1.2-3.4-1.6-1.8-2.1-1.8-1.71.41.2-0.3-1.7-1.51.1-1.3-1.41.7-2.7-2.7
Reaction time trials AUC1.63.110.5-2.11.7-2.2-2.2-2.2-1.60.3-1.5-0.9-3.2-1.4-1.6-2.0-1.5-1.41.31.1-0.4-1.6-1.41.0-1.3-1.41.8-2.6-2.6
Run reversals in cocaine runway, females0.10.10.4-0.1-0.10.10.10.1-0.00.4-0.0-0.0-0.3-0.3-0.4-0.4-0.20.30.50.40.3-0.4-0.50.5-0.6-0.50.70.10.1
Run reversals in cocaine runway, males4.74.77.2-2.02.4-1.0-1.0-1.0-2.3-1.5-2.0-1.9-2.1-2.5-2.6-2.7-2.5-2.42.52.51.8-2.6-2.52.3-2.3-2.41.9-2.3-2.3
Latency to leave start box in cocaine runway9.010.218.63.9-4.32.72.72.74.32.63.93.83.73.93.83.83.63.6-2.9-2.9-2.23.02.9-2.42.22.4-1.42.62.6
Latency to leave start box in cocaine runway, F6.17.012.03.0-3.31.81.81.83.51.93.02.93.03.23.33.33.03.0-2.6-2.5-1.92.72.7-2.32.12.2-1.52.52.5
Latency to leave start box in cocaine runway, M4.84.59.83.1-3.12.82.82.83.02.23.02.82.62.42.12.12.22.2-1.3-1.4-1.01.31.2-0.80.70.7-0.01.11.1
Std. dev. time between licks in bursts1.82.44.52.0-2.02.12.12.01.92.12.12.01.41.71.51.31.72.0-1.0-1.3-1.01.00.9-0.70.80.70.00.90.9
Total sessions with >9 infusions3.23.911.62.6-2.43.43.43.42.11.91.81.32.4-0.0-0.1-0.2-0.0-0.21.61.62.3-1.5-1.72.3-2.3-2.12.2-0.4-0.4
Short access day 1 total inactive lever presses0.00.00.3-0.30.1-0.2-0.2-0.1-0.20.5-0.1-0.0-0.3-0.1-0.1-0.2-0.1-0.20.10.1-0.1-0.2-0.10.1-0.1-0.10.2-0.3-0.3
Short access day 10 total inactive lever presses1.12.87.8-0.3-0.0-1.3-1.3-1.30.20.10.40.8-0.61.61.71.61.51.4-2.4-2.4-2.82.22.3-2.62.62.4-1.90.90.9
Short access day 1 total infusions2.22.99.12.3-2.23.03.03.01.91.91.81.42.00.2-0.0-0.10.20.11.31.11.6-1.1-1.31.8-1.8-1.71.9-0.5-0.5
Short access day 10 total infusions0.70.92.11.0-1.01.41.41.50.80.90.60.40.9-0.2-0.4-0.4-0.3-0.31.00.91.3-0.9-1.01.3-1.3-1.21.2-0.2-0.2
Short access total infusions1.82.36.61.9-1.92.52.52.61.61.81.41.01.80.0-0.2-0.20.00.01.31.11.7-1.1-1.31.7-1.7-1.61.6-0.2-0.2
Short access day 1 locomotion0.50.71.91.3-1.41.31.31.21.31.01.21.01.20.70.50.60.70.70.1-0.10.20.10.00.2-0.3-0.20.40.40.4
Short access day 10 total locomotion0.10.20.6-0.40.2-0.7-0.7-0.8-0.2-0.2-0.4-0.40.0-0.1-0.10.20.20.3-0.2-0.2-0.00.30.3-0.40.40.4-0.70.80.8
Short access total locomotion0.60.72.01.3-1.21.31.31.41.01.00.80.51.40.10.10.20.10.10.60.61.1-0.4-0.50.8-0.9-0.70.60.30.3
One hour access (0.3 mA shock)1.82.15.60.30.21.21.21.3-0.4-0.0-0.3-0.60.5-1.4-1.4-1.4-1.2-1.12.12.02.4-2.0-2.12.3-2.2-2.11.6-0.9-0.9
Compulsive drug intake0.30.30.9-0.10.60.10.10.1-0.5-0.0-0.4-0.50.1-0.7-0.6-0.5-0.7-0.70.70.81.0-0.7-0.70.8-0.8-0.70.4-0.4-0.4
One hour access (shock baseline)0.81.22.90.00.00.80.80.8-0.3-0.2-0.2-0.40.3-1.1-1.2-1.1-0.8-0.81.71.51.7-1.5-1.61.7-1.6-1.61.2-0.7-0.7
Social response proportion0.80.91.7-1.01.1-0.7-0.7-0.6-1.0-0.3-1.0-0.9-1.3-1.0-0.8-1.2-1.3-1.30.60.90.4-0.9-0.90.7-0.7-0.80.7-1.3-1.3
Social responses1.01.23.7-1.11.4-0.6-0.6-0.6-1.3-0.1-0.9-0.6-1.9-1.0-1.2-1.5-1.2-1.01.00.90.0-1.2-1.20.9-0.9-1.11.3-1.7-1.7
Social time2.93.910.41.5-2.00.60.60.42.21.92.32.80.22.72.62.12.42.4-2.5-2.5-3.22.02.1-2.11.81.7-0.40.30.3
Soleus weight0.10.31.20.6-1.10.70.70.51.00.90.70.60.90.50.20.50.70.50.1-0.10.10.20.2-0.0-0.10.00.00.50.5
Bone: stiffness1.42.34.41.7-1.81.11.11.11.81.41.81.91.31.92.11.81.71.4-1.8-1.6-1.51.51.5-1.41.31.3-0.60.60.6
Tibialis anterior weight0.20.62.80.5-0.80.70.70.71.01.70.91.2-0.30.60.3-0.00.2-0.20.3-0.1-0.7-0.3-0.20.3-0.5-0.51.2-1.3-1.3
Time to tail flick, vehicle, before self-admin1.61.72.9-1.71.7-1.4-1.4-1.4-1.6-0.9-1.7-1.7-1.1-1.6-1.6-1.3-1.5-1.61.31.21.2-1.1-1.10.9-0.9-0.80.3-0.7-0.7
Time to tail flick, vehicle, after self-admin0.70.93.1-1.21.5-1.3-1.3-1.3-1.4-1.8-1.1-1.0-1.1-0.4-0.3-0.2-0.4-0.4-0.6-0.4-0.50.40.4-0.71.00.8-1.10.00.0
Time to tail flick, test, before self-admin0.40.42.1-0.90.7-1.1-1.1-1.1-0.6-1.5-0.8-0.7-0.7-0.3-0.1-0.1-0.2-0.3-0.3-0.1-0.40.20.3-0.50.50.4-0.7-0.1-0.1
Time to tail flick, test, after self-admin1.01.03.4-1.51.4-1.8-1.8-1.9-1.3-1.6-1.3-1.2-1.3-0.6-0.5-0.4-0.6-0.8-0.1-0.1-0.40.20.3-0.60.60.5-0.8-0.2-0.2
Delta time to tail flick, vehicle, before/after SA0.80.82.2-0.30.1-0.7-0.7-0.8-0.1-0.8-0.00.2-0.60.70.80.70.50.7-1.4-1.2-1.51.11.1-1.31.41.3-1.10.30.3
Delta time to tail flick, test, before/after SA0.10.10.90.4-0.30.40.40.30.31.00.50.5-0.10.30.10.00.1-0.0-0.0-0.1-0.3-0.0-0.00.1-0.2-0.10.6-0.4-0.4
Tibia length0.20.62.4-1.10.5-1.5-1.5-1.6-0.3-0.5-0.30.0-1.10.3-0.50.20.3-0.2-0.1-0.7-1.30.50.6-0.80.70.7-0.4-0.3-0.3
Ambulatory time before self-admin0.10.10.50.4-0.50.40.40.50.60.70.40.30.60.10.10.10.10.30.20.20.4-0.1-0.20.3-0.5-0.30.40.30.3
Ambulatory time after self-admin2.22.65.81.9-2.21.51.51.52.41.82.02.01.71.92.01.81.71.9-1.4-1.3-1.11.41.4-1.10.91.0-0.41.31.3
Bone: tissue strength0.70.72.70.7-0.80.00.00.00.81.21.01.3-0.51.11.10.61.01.2-0.9-0.9-1.60.50.6-0.60.50.40.4-0.2-0.2
Total heroin consumption0.10.10.40.2-0.20.60.60.60.20.30.20.2-0.0-0.1-0.3-0.3-0.10.10.40.30.2-0.5-0.50.5-0.5-0.60.7-0.4-0.4
Bone: trabecular number0.91.53.41.0-1.30.40.40.41.21.21.41.60.51.61.91.41.61.5-1.7-1.5-1.71.31.3-1.31.11.1-0.40.40.4
Bone: trabecular spacing0.81.13.8-1.61.7-1.6-1.6-1.7-1.4-2.0-1.5-1.4-1.0-0.9-1.1-0.6-0.8-0.70.40.20.2-0.1-0.1-0.10.20.2-0.70.10.1
Bone: trabecular thickness0.30.41.20.6-0.50.90.90.80.10.40.20.00.7-0.3-0.2-0.2-0.4-0.50.70.81.1-0.6-0.70.9-0.9-0.80.6-0.3-0.3
Bone: trabecular tissue density0.40.62.4-0.50.20.20.2-0.3-0.4-0.9-0.6-0.90.8-0.8-1.4-0.3-0.5-0.51.40.91.5-0.5-0.60.7-0.6-0.5-0.20.70.7
Water consumed over 24 hours0.40.61.4-0.20.2-1.0-1.0-1.10.0-0.8-0.3-0.20.00.40.70.70.10.1-1.0-0.8-0.70.91.0-1.11.11.1-1.20.60.6
Number of responses in last shaping day0.60.71.30.7-1.20.40.40.41.11.10.91.00.51.11.00.90.91.0-0.9-0.9-1.00.80.8-0.80.70.7-0.40.50.5