Hub : Genes

Grk4

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 pVTA isoform ratio NM_022928.1 0.04 0.03 3.7e-04 0.03 0.04 0.04 0.04 9.0e-04 3.0e-04 3.0e-04 6.0e-04
2 Brain gene expression Grk4 0.03 0.02 2.5e-03 0.01 0.02 0.02 0.01 1.7e-02 6.2e-03 9.0e-03 2.0e-02
3 Brain alternative polyA XM_039092357.2 0.02 0.02 4.9e-03 0.02 0.02 0.01 0.01 6.2e-03 3.1e-03 1.6e-02 1.6e-02
4 Brain mRNA stability Grk4 0.08 0.05 2.9e-07 0.06 0.07 0.07 0.07 3.4e-06 1.8e-07 3.9e-07 3.4e-07
5 NAcc gene expression Grk4 0.01 0.01 4.3e-03 0.02 0.01 0.02 0.02 6.3e-04 4.9e-03 4.1e-04 1.3e-03
6 PL alternative polyA XM_063273520.1 0.05 0.03 2.5e-06 0.03 0.05 0.05 0.04 2.1e-04 4.2e-06 4.8e-06 1.3e-05
7 Adipose gene expression Grk4 0.05 0.03 3.1e-06 0.05 0.05 0.04 0.04 4.3e-06 6.6e-06 1.9e-05 8.7e-06
8 Adipose alternative TSS XM_063273525.1 0.02 0.01 9.2e-03 0.02 0.01 0.01 0.01 5.2e-03 1.2e-02 2.0e-02 1.0e-02
9 Adipose alternative polyA XM_063273520.1 0.01 0.01 9.9e-03 0 -0 -0 -0 8.0e-02 5.5e-01 6.1e-01 5.1e-01
10 Liver intron excision ratio chr14_80283357_80294173 0.08 0.05 3.2e-10 0.08 0.07 0.07 0.07 8.7e-09 6.6e-08 5.3e-08 3.2e-08
11 Liver isoform ratio NM_022928.1 0.04 0.03 8.4e-05 0.04 0.03 0.03 0.03 7.9e-05 1.1e-04 1.9e-04 9.9e-05
12 PL alternative TSS NM_022928.1 0.05 0.06 5.5e-04 0.02 0.02 0.01 0.02 4.3e-03 1.5e-03 1.3e-02 1.5e-03
13 Adipose mRNA stability Grk4 0.02 0.01 4.7e-03 0.02 0.02 0.02 0.02 1.2e-03 2.0e-03 1.8e-03 1.3e-03
14 BLA mRNA stability Grk4 0.07 0.06 3.2e-04 0.05 0.04 0.01 0.04 1.1e-03 3.9e-03 6.3e-02 3.0e-03
15 Eye mRNA stability Grk4 0.27 0.18 7.9e-03 0.09 0.07 0.03 0.07 1.7e-02 3.7e-02 1.3e-01 2.8e-02
16 IC alternative polyA XM_039092356.2 0.07 0.05 1.8e-03 0.06 0.05 0.05 0.05 1.1e-03 2.8e-03 2.8e-03 2.7e-03
17 pVTA alternative polyA XM_063273520.1 0.04 0.03 1.2e-03 0.03 0.02 0.03 0.03 1.0e-03 4.6e-03 3.6e-03 2.7e-03
18 BLA alternative TSS XM_063273534.1 0.06 0.05 1.2e-03 0.05 0.02 0.05 0.03 1.2e-03 2.2e-02 1.3e-03 8.9e-03
19 PL alternative TSS XM_063273534.1 0.15 0.12 1.9e-04 0.02 0.03 0.04 0.02 3.2e-03 6.5e-04 5.7e-05 2.5e-03

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density0.61.01.7-1.2-1.2-1.31.10.61.0-1.0-1.0-1.01.0-1.0-0.91.01.01.0-1.01.01.1-0.0
Area under the delay curve0.30.31.60.10.10.6-0.31.30.00.70.60.6-0.60.50.2-0.5-0.5-0.50.5-0.5-0.5-0.6
BMI with tail0.93.28.12.12.12.7-1.8-2.8-1.41.71.61.7-1.71.71.1-1.7-1.7-1.71.7-1.7-1.60.4
BMI without tail0.51.44.21.71.62.0-1.3-1.8-1.11.21.01.0-1.01.00.7-0.9-0.9-0.90.9-0.9-1.00.7
Body weight5.122.531.85.25.25.6-5.1-0.9-4.84.84.94.9-4.94.94.5-5.0-5.0-5.05.0-5.0-4.7-2.0
Weight adjusted by age2.33.44.81.91.92.2-1.9-0.5-1.71.81.81.8-1.81.91.6-2.1-2.1-2.12.1-2.1-1.8-1.2
Bone surface0.61.14.20.50.60.6-0.82.0-0.71.01.01.0-1.01.01.0-1.0-1.0-1.01.0-1.0-0.9-1.4
Bone volume0.00.00.3-0.1-0.1-0.1-0.00.50.00.10.10.1-0.10.10.1-0.1-0.1-0.10.1-0.10.0-0.4
Breakpoint value in progressive ratio session0.20.20.6-0.3-0.3-0.30.3-0.30.3-0.5-0.3-0.30.3-0.2-0.40.50.50.5-0.50.50.40.8
Number of licking bursts1.82.93.61.81.81.5-1.81.1-1.91.91.91.9-1.91.71.9-1.7-1.7-1.71.7-1.7-1.7-0.9
Context. condit. distance diff. score0.50.61.2-0.7-0.7-0.70.80.80.8-0.3-0.3-0.30.3-0.8-0.90.80.80.8-0.80.80.81.1
Locomotion velocity, session 11.21.31.8-1.1-1.2-1.31.20.81.1-1.1-1.1-1.11.1-1.3-1.11.31.31.3-1.31.31.20.8
Locomotion distance, session 10.40.50.6-0.8-0.8-0.80.70.20.7-0.8-0.8-0.80.8-0.6-0.60.60.60.6-0.60.60.60.1
Locomotion velocity, session 23.74.37.3-2.2-2.2-2.72.22.41.8-1.9-1.9-1.91.9-2.2-1.72.22.22.2-2.22.22.10.7
Locomotion distance, session 22.43.35.1-2.3-2.2-2.12.01.92.1-1.8-1.8-1.81.8-1.7-1.71.71.71.7-1.71.71.70.0
Locomotion velocity, session 30.20.23.0-0.5-0.5-0.40.31.70.40.10.10.1-0.1-0.0-0.20.00.00.0-0.00.00.1-0.5
Locomotion distance, session 30.10.11.5-0.1-0.10.10.01.20.20.30.30.3-0.30.0-0.1-0.0-0.0-0.00.0-0.0-0.00.0
Stereotopy head waving bouts, day 33.44.010.8-1.3-1.4-1.51.8-3.31.6-1.7-1.7-1.71.7-2.1-2.02.12.12.1-2.12.12.12.6
Stereotopy head waving duration, day 33.03.611.6-1.3-1.3-1.31.7-3.41.6-1.7-1.7-1.71.7-1.9-1.91.91.91.9-1.91.91.92.2
Locomotion velocity, session 72.83.04.41.41.41.2-1.71.9-1.72.12.12.1-2.11.71.9-1.7-1.7-1.71.7-1.7-1.7-1.1
Locomotion distance, session 70.40.57.8-0.3-0.3-0.2-0.02.80.10.60.60.6-0.60.30.2-0.3-0.3-0.30.3-0.3-0.3-0.6
Stereotopy head waving bouts, day 70.50.55.60.50.50.9-0.2-2.4-0.10.40.40.4-0.40.1-0.3-0.1-0.1-0.10.1-0.1-0.11.5
Stereotopy head waving duration, day 70.91.14.41.21.11.5-1.0-2.1-0.81.11.11.1-1.10.80.5-0.8-0.8-0.80.8-0.8-0.80.8
Locomotion velocity, session 80.80.92.0-1.1-1.1-1.41.01.40.8-0.8-0.8-0.80.8-1.0-0.71.01.01.0-1.01.01.00.0
Locomotion distance, session 82.13.04.1-1.9-1.9-2.01.92.01.8-1.3-1.3-1.31.3-1.8-1.71.81.81.8-1.81.81.81.2
Degree of sensitization distance0.20.21.5-0.5-0.5-0.90.41.20.2-0.3-0.3-0.30.3-0.4-0.00.40.40.4-0.40.40.4-0.3
Degree of sensitization stereotypy0.91.02.21.21.11.5-1.0-1.5-0.81.01.01.0-1.00.90.6-0.9-0.9-0.90.9-0.9-0.90.5
Conditioned locomotion0.60.72.00.10.10.6-0.51.4-0.10.60.80.8-0.80.90.5-0.9-0.9-0.90.9-0.9-1.0-1.4
Cocaine response after cond. corrected2.22.73.4-1.7-1.7-1.51.8-1.11.8-1.7-1.5-1.61.6-1.7-1.81.71.71.7-1.71.71.71.3
Cocaine response after cond. not corrected1.01.21.5-1.1-1.1-1.01.2-0.81.2-1.1-1.0-1.01.0-1.1-1.21.11.11.1-1.11.11.10.9
Cocaine response before conditioning1.41.62.11.31.41.1-1.41.0-1.51.41.21.3-1.31.31.4-1.3-1.3-1.31.3-1.3-1.2-0.9
Saline control response0.20.20.7-0.4-0.4-0.50.50.80.4-0.5-0.5-0.50.5-0.5-0.40.50.50.5-0.50.50.50.4
Bone: connectivity density0.30.51.5-1.0-0.9-0.90.71.20.8-0.6-0.6-0.60.6-0.6-0.60.60.60.6-0.60.60.7-0.4
Bone: cortical apparent density0.50.79.6-0.1-0.10.30.4-3.10.5-0.3-0.4-0.40.4-0.5-0.80.50.50.5-0.50.50.51.2
Bone: cortical area6.29.513.23.23.23.2-3.22.3-3.13.63.33.2-3.23.13.0-3.1-3.1-3.13.1-3.1-3.0-1.0
Bone: cortical porosity0.30.41.1-0.7-0.7-0.70.61.10.6-0.4-0.6-0.60.6-0.6-0.50.60.60.6-0.60.60.50.1
Bone: cortical porosity0.30.32.3-0.4-0.4-0.30.41.50.5-0.0-0.4-0.40.4-0.5-0.50.50.50.5-0.50.50.40.5
Bone: cortical thickness3.05.08.82.42.42.6-2.32.0-2.13.02.42.4-2.42.21.9-2.2-2.2-2.22.2-2.2-2.10.0
Bone: cortical thickness0.20.23.0-0.2-0.20.4-0.1-1.70.30.10.40.4-0.40.3-0.1-0.3-0.3-0.30.3-0.3-0.3-0.5
Bone: cortical tissue density0.71.011.4-0.2-0.20.20.5-3.40.6-0.5-0.6-0.50.5-0.6-0.90.60.60.6-0.60.60.71.4
Condit. Reinf. active minus inactive responses2.22.44.1-1.5-1.5-1.31.6-2.01.6-1.6-1.6-1.61.6-1.5-1.61.51.51.5-1.51.51.51.2
Condit. Reinf. active-inactive response ratio4.04.25.0-2.1-2.1-2.02.2-1.12.1-2.2-2.2-2.22.2-2.1-2.12.12.12.1-2.12.12.11.4
Condit. Reinf. active responses1.01.23.9-1.0-1.0-0.91.0-2.01.1-1.1-1.1-1.11.1-1.0-1.11.01.01.0-1.01.01.00.9
Condit. Reinf. inactive responses1.62.02.31.51.51.4-1.5-0.6-1.51.51.51.5-1.51.51.5-1.5-1.5-1.51.5-1.5-1.5-0.9
Incentive salience index mean0.30.44.4-0.4-0.4-0.30.4-2.10.5-0.6-0.6-0.60.6-0.4-0.50.40.40.4-0.40.40.40.5
Condit. Reinf. lever presses1.01.43.61.11.11.2-1.2-1.9-1.10.90.90.9-0.91.31.1-1.3-1.3-1.31.3-1.3-1.3-0.8
Condit. Reinf. active minus inactive responses0.70.91.51.11.10.8-1.10.7-1.21.00.80.9-0.90.91.2-0.9-0.9-0.90.9-0.9-0.9-0.7
Condit. Reinf. active-inactive response ratio0.10.10.2-0.4-0.3-0.20.3-0.10.4-0.2-0.4-0.30.3-0.2-0.30.20.20.2-0.20.20.3-0.2
Condit. Reinf. active responses0.10.20.60.30.3-0.0-0.40.8-0.50.50.20.3-0.30.30.6-0.3-0.3-0.30.3-0.3-0.2-0.8
Condit. Reinf. inactive responses0.00.00.20.00.0-0.3-0.0-0.4-0.20.00.00.0-0.0-0.10.20.10.10.1-0.10.10.1-0.1
Condit. Reinf. lever presses0.30.40.60.70.70.7-0.70.8-0.60.80.60.8-0.80.60.6-0.6-0.6-0.60.6-0.6-0.6-0.3
Condit. Reinf. lever reinforcers received0.20.30.80.40.40.2-0.50.9-0.60.70.40.6-0.60.50.7-0.5-0.5-0.50.5-0.5-0.5-0.9
Conditioned reinforcement - actives0.40.71.00.70.70.9-0.8-0.2-0.60.80.80.8-0.80.80.7-1.0-1.0-1.01.0-1.0-0.8-1.0
Conditioned reinforcement - inactives0.60.91.11.11.11.1-1.1-0.2-1.01.01.01.0-1.01.01.0-1.0-1.0-1.01.0-1.0-1.0-0.7
Conditioned locomotion1.01.31.81.21.21.3-1.2-0.1-1.11.21.21.2-1.21.21.1-1.2-1.2-1.21.2-1.2-1.2-1.0
Patch foraging indifference point 0 sec0.10.21.6-0.2-0.2-0.30.3-1.30.2-0.2-0.4-0.30.3-0.4-0.40.30.30.3-0.30.30.51.1
Patch foraging indifference point AUC0.40.50.9-0.5-0.5-0.70.60.20.4-0.8-0.9-0.80.8-0.7-0.50.90.90.9-0.90.90.70.4
Delay disc. indifference point, 0s delay0.60.73.4-0.2-0.10.8-0.31.80.41.00.70.8-0.80.70.0-0.8-0.8-0.80.8-0.8-0.8-1.3
Delay disc. indifference point, 16s delay0.20.20.4-0.5-0.5-0.30.5-0.10.6-0.4-0.4-0.40.4-0.4-0.50.50.50.5-0.50.50.70.2
Delay disc. indifference point, 2s delay0.20.22.8-0.6-0.50.00.31.70.70.20.00.1-0.10.0-0.4-0.0-0.0-0.00.0-0.0-0.2-0.6
Delay disc. indifference point, 24s delay0.10.10.3-0.2-0.20.5-0.00.60.40.40.30.3-0.30.3-0.2-0.2-0.2-0.20.2-0.2-0.0-0.1
Delay disc. indifference point, 4s delay0.30.32.3-0.7-0.6-0.40.41.50.6-0.2-0.3-0.30.3-0.3-0.40.30.30.3-0.30.30.2-0.5
Delay disc. indifference point, 8s delay0.80.91.20.90.91.1-1.00.5-0.91.11.01.0-1.01.00.9-1.0-1.0-1.01.0-1.0-0.8-0.4
Indifference point function ln k0.10.20.7-0.4-0.4-0.60.4-0.90.2-0.3-0.3-0.30.3-0.4-0.30.30.30.3-0.30.30.50.4
Indifference point function log k0.10.20.7-0.4-0.4-0.60.4-0.90.2-0.3-0.3-0.30.3-0.4-0.30.30.30.3-0.30.30.50.4
Patch foraging total patch changes 0 sec0.10.21.5-0.1-0.1-0.20.3-1.20.2-0.2-0.3-0.30.3-0.4-0.30.20.20.2-0.20.20.51.2
Patch foraging total patch changes 12 sec0.20.30.40.60.60.7-0.6-0.6-0.60.40.40.3-0.30.60.5-0.5-0.5-0.50.5-0.5-0.5-0.3
Patch foraging total patch changes 18 sec0.10.21.7-0.1-0.2-0.20.3-1.30.2-0.5-0.5-0.40.4-0.3-0.30.50.50.5-0.50.50.40.5
Patch foraging total patch changes 24 sec0.10.20.7-0.4-0.4-0.10.50.10.6-0.1-0.4-0.30.3-0.5-0.70.60.60.6-0.60.60.50.8
Patch foraging total patch changes 6 sec0.10.21.40.30.2-0.10.0-1.2-0.2-0.3-0.4-0.30.3-0.3-0.00.30.30.3-0.30.30.30.7
Patch foraging time to switch 0 sec0.71.32.20.90.91.5-1.10.8-0.61.31.41.3-1.31.20.7-1.3-1.3-1.31.3-1.3-1.3-0.8
Patch foraging water rate 0 sec0.40.82.71.41.40.6-1.2-0.1-1.60.90.50.7-0.70.81.4-0.6-0.6-0.60.6-0.6-0.70.1
Patch foraging water rate 12 sec0.30.62.6-0.2-0.2-0.60.6-0.80.3-0.7-0.8-0.80.8-0.9-0.60.80.80.8-0.80.80.91.6
Patch foraging water rate 18 sec0.30.43.80.30.3-0.10.2-1.3-0.2-0.2-0.4-0.30.3-0.5-0.30.60.60.6-0.60.60.61.9
Patch foraging water rate 24 sec0.40.52.81.11.10.5-0.6-1.7-1.10.20.00.1-0.10.20.6-0.1-0.1-0.10.1-0.1-0.11.5
Patch foraging water rate 6 sec0.60.82.21.51.40.9-1.1-1.0-1.40.80.60.6-0.60.61.0-0.6-0.6-0.60.6-0.6-0.50.8
Seeking ratio, delayed vs. immediate footshock1.82.33.5-1.4-1.4-1.91.5-1.11.1-1.8-1.7-1.71.7-1.5-1.31.51.51.5-1.51.51.61.0
Distance traveled before self-admin0.91.21.9-1.4-1.4-1.31.20.11.3-1.1-1.1-1.11.1-1.0-1.11.21.21.2-1.21.21.10.1
Distance traveled after self-admin0.10.10.3-0.5-0.5-0.10.30.30.6-0.2-0.1-0.10.10.0-0.40.10.10.1-0.10.10.1-0.5
Extensor digitorum longus weight1.76.710.63.33.23.2-2.8-2.6-2.92.42.52.5-2.52.52.4-2.5-2.5-2.52.5-2.5-2.30.4
Bone: elastic displacement1.41.61.81.31.31.2-1.31.1-1.31.01.31.3-1.31.31.4-1.3-1.3-1.31.3-1.3-1.3-1.2
Bone: elastic work3.64.76.42.52.52.3-2.40.1-2.52.12.32.3-2.32.22.3-2.2-2.2-2.22.2-2.2-2.2-0.7
Bone: endosteal estimation1.94.25.52.02.01.6-2.12.0-2.32.22.12.1-2.12.12.3-2.1-2.1-2.12.1-2.1-2.1-1.6
Bone: endosteal perimeter2.14.45.72.02.01.7-2.21.5-2.32.02.22.1-2.12.22.4-2.2-2.2-2.22.2-2.2-2.1-1.8
Epididymis fat weight1.96.68.72.62.63.0-2.7-1.5-2.42.52.42.4-2.42.72.4-2.8-2.8-2.82.8-2.8-2.7-2.0
Delta time in closed arm before/after self-admin1.01.01.3-1.1-1.1-0.91.00.51.1-0.9-0.9-0.90.9-0.8-1.01.11.11.1-1.11.10.90.4
Delta time in open arm before/after self-admin1.61.62.11.31.31.4-1.3-0.1-1.21.31.31.3-1.31.31.2-1.4-1.4-1.41.4-1.4-1.3-0.9
Diff in mean of infusions in LGA sessions1.11.32.5-1.5-1.5-1.11.40.01.6-1.2-1.1-1.11.1-1.1-1.41.11.11.1-1.11.11.20.3
Delay discount exponential model param0.20.21.4-0.0-0.0-0.50.2-1.2-0.1-0.6-0.5-0.50.5-0.4-0.10.40.40.4-0.40.40.30.6
Extinction: sum of active levers before priming0.70.81.30.90.91.1-1.00.1-0.81.01.01.0-1.01.10.9-0.9-0.9-0.90.9-0.9-1.0-0.4
Active lever presses in extinction session 60.00.00.2-0.3-0.30.20.20.30.5-0.0-0.0-0.00.0-0.0-0.40.10.10.1-0.10.10.0-0.1
Bone: final force6.09.614.73.13.13.0-3.23.2-3.13.83.33.3-3.33.13.1-3.1-3.1-3.13.1-3.1-3.0-1.3
Bone: final moment4.67.312.12.82.82.7-2.83.0-2.83.52.92.8-2.82.62.6-2.6-2.6-2.62.6-2.6-2.6-0.6
Food consumed during 24 hour testing period0.00.10.30.30.3-0.2-0.1-0.6-0.50.10.10.1-0.1-0.10.30.10.10.1-0.10.10.10.3
Glucose0.40.71.60.70.70.2-0.81.3-1.11.01.11.1-1.10.71.1-0.6-0.6-0.60.6-0.6-0.7-0.5
Heart weight1.62.52.81.61.61.5-1.61.6-1.71.61.71.7-1.71.51.6-1.7-1.7-1.71.7-1.7-1.5-0.9
Delay discount hyperbolic model param0.20.21.90.10.1-0.40.2-1.4-0.2-0.6-0.4-0.40.4-0.4-0.00.40.40.4-0.40.40.40.5
Intermittent access intake day 1-15 change2.34.76.4-2.5-2.5-2.52.5-0.22.4-2.3-2.3-2.32.3-2.3-2.32.02.02.0-2.02.02.30.9
Intermittent access intake escalation1.53.14.3-2.1-2.1-2.02.0-0.32.0-1.9-1.9-1.91.9-1.9-1.91.61.61.6-1.61.61.90.8
Intermittent access intake escalation 22.42.73.9-1.8-1.8-2.01.9-0.41.7-1.8-1.8-1.81.8-1.8-1.71.51.51.5-1.51.51.80.9
Intermitt. access day 1 inactive lever presses0.10.50.8-0.7-0.7-0.90.80.10.6-0.8-0.8-0.80.8-0.8-0.70.80.80.8-0.80.80.80.2
Intermitt. access day 15 inactive lever presses0.30.71.0-0.9-0.9-1.00.9-0.10.8-0.9-0.9-0.90.9-0.9-0.80.80.80.8-0.80.80.90.7
Intermitt. access escalation Index0.60.81.2-1.0-1.0-1.11.0-0.20.9-1.0-1.0-1.01.0-1.0-0.90.80.80.8-0.80.81.00.2
Intermittent access day 1 total infusions0.61.01.60.80.81.3-1.00.1-0.71.11.11.1-1.11.10.8-1.1-1.1-1.11.1-1.1-1.1-0.9
Intermittent access day 15 total infusions0.00.00.2-0.2-0.2-0.00.1-0.40.2-0.0-0.0-0.00.0-0.0-0.2-0.2-0.2-0.20.2-0.20.0-0.2
Intermittent access terminal intake (last 3 days)0.10.10.2-0.3-0.3-0.30.3-0.50.3-0.3-0.3-0.30.3-0.3-0.3-0.0-0.0-0.00.0-0.00.30.0
Intermittent access total infusions0.10.20.20.30.30.4-0.4-0.3-0.30.40.40.4-0.40.40.3-0.5-0.5-0.50.5-0.5-0.4-0.2
Intermittent access day 1 locomotion0.50.71.10.80.81.0-0.90.1-0.70.90.90.9-0.90.90.8-0.8-0.8-0.80.8-0.8-0.9-0.6
Intermittent access day 15 total locomotion0.10.20.50.30.30.7-0.50.1-0.20.60.60.6-0.60.60.3-0.5-0.5-0.50.5-0.5-0.6-0.5
Intermittent access total locomotion0.00.00.0-0.0-0.00.1-0.0-0.10.10.10.10.1-0.10.1-0.0-0.1-0.1-0.10.1-0.1-0.1-0.1
Intermittent access standard deviation0.30.70.8-0.9-0.9-0.90.90.10.8-0.8-0.8-0.80.8-0.8-0.80.80.80.8-0.80.80.80.4
Left kidney weight3.214.822.54.74.64.7-4.30.7-4.24.14.24.2-4.23.83.7-3.7-3.7-3.73.7-3.7-3.8-0.1
Right kidney weight2.410.717.63.83.84.2-3.60.6-3.33.63.63.7-3.73.33.0-3.1-3.1-3.13.1-3.1-3.2-0.3
Cocaine induced anxiety0.60.91.5-0.8-0.8-1.00.90.50.7-0.8-0.8-0.80.8-0.8-0.71.21.21.2-1.21.20.80.9
Post-drug Anxiety0.40.40.7-0.7-0.7-0.40.60.80.8-0.4-0.4-0.40.4-0.4-0.60.80.80.8-0.80.80.40.3
Baseline Anxiety1.51.72.71.01.01.6-1.30.2-0.81.41.41.4-1.41.41.0-1.5-1.5-1.51.5-1.5-1.4-1.5
Tail length0.93.55.52.32.31.9-2.11.7-2.41.91.91.9-1.91.92.1-1.6-1.6-1.61.6-1.6-1.8-0.6
Length with tail4.117.723.14.84.84.4-4.70.8-4.84.14.44.4-4.44.34.6-4.2-4.2-4.24.2-4.2-4.2-2.0
Length without tail3.812.114.33.73.83.6-3.8-0.2-3.73.33.63.6-3.63.63.6-3.7-3.7-3.73.7-3.7-3.5-2.0
Times rat made contact with spout0.80.91.5-0.9-0.9-1.21.0-0.60.7-0.9-0.9-0.90.9-1.1-0.71.11.11.1-1.11.11.10.6
Lifetime Intake0.20.20.20.40.40.5-0.5-0.2-0.40.40.40.4-0.40.40.4-0.5-0.5-0.50.5-0.5-0.4-0.1
Liver weight, left0.50.91.11.01.01.0-1.00.8-1.01.01.11.0-1.01.01.0-0.9-0.9-0.90.9-0.9-0.9-0.4
Liver weight, right2.03.69.42.32.22.4-2.0-3.1-1.91.51.41.4-1.41.81.6-1.9-1.9-1.91.9-1.9-1.8-0.2
Locomotor activity0.40.61.70.90.90.2-0.90.8-1.30.70.60.7-0.70.71.2-0.6-0.6-0.60.6-0.6-0.6-0.4
Locomotor testing distance0.61.01.61.21.21.0-1.2-0.3-1.31.01.11.1-1.11.11.2-0.9-0.9-0.90.9-0.9-1.1-0.1
Locomotor testing rearing1.12.23.61.81.81.5-1.7-0.4-1.91.51.51.6-1.61.51.7-1.4-1.4-1.41.4-1.4-1.5-0.1
Locomotion in novel chamber0.50.71.2-1.0-1.0-0.91.00.31.1-0.7-0.7-0.70.7-0.9-1.10.70.70.7-0.70.70.70.5
Locomotion in novel chamber post-restriction0.10.10.7-0.5-0.4-0.20.30.80.5-0.10.10.1-0.1-0.1-0.30.10.10.1-0.10.1-0.1-0.5
Fecal boli incidents, locomotor time 10.30.41.3-0.6-0.6-0.80.7-1.10.5-0.8-0.7-0.70.7-0.7-0.60.40.40.4-0.40.40.70.6
Change in fecal boli incidents, locomotor task0.40.41.4-0.5-0.5-0.70.61.20.4-0.4-0.5-0.50.5-0.7-0.50.80.80.8-0.80.80.70.2
Time >=10cm from walls, locomotor time 11.31.42.41.01.01.6-1.20.3-0.81.31.31.3-1.31.30.9-1.2-1.2-1.21.2-1.2-1.3-1.4
Bouts of movement, locomotor time 10.10.10.60.20.20.5-0.2-0.8-0.00.20.20.2-0.20.2-0.0-0.1-0.1-0.10.1-0.1-0.1-0.4
Total resting periods, locomotor time 10.10.10.30.20.20.5-0.2-0.3-0.00.30.30.3-0.30.20.0-0.2-0.2-0.20.2-0.2-0.2-0.6
Rest time, locomotor task time 12.02.63.71.91.91.6-1.8-0.7-1.91.51.51.5-1.51.51.7-1.6-1.6-1.61.6-1.6-1.3-1.3
Distance moved, locomotor task time 10.40.62.1-0.7-0.7-0.50.71.10.8-0.4-0.5-0.60.6-0.8-0.80.80.80.8-0.80.80.61.5
Vertical activity count, locomotor time 10.71.72.0-1.4-1.4-1.41.41.01.4-1.2-1.2-1.21.2-1.2-1.31.41.41.4-1.41.41.40.8
Time >=10cm from walls, locomotor time 20.81.11.80.90.91.1-1.1-0.5-0.90.91.00.9-0.91.11.0-1.3-1.3-1.31.3-1.3-0.7-1.1
Bouts of movement, locomotor time 20.10.21.6-0.4-0.4-0.10.3-1.30.5-0.3-0.2-0.30.3-0.2-0.40.10.10.1-0.10.10.30.4
Total resting periods, locomotor time 20.00.11.1-0.0-0.00.3-0.0-1.00.20.00.10.0-0.00.2-0.1-0.2-0.2-0.20.2-0.20.00.1
Rest time, locomotor task time 21.31.62.51.61.61.3-1.50.2-1.61.21.21.2-1.21.31.5-1.1-1.1-1.11.1-1.1-1.0-1.4
Distance moved, locomotor task time 20.70.81.2-1.1-1.1-0.91.00.51.1-0.8-0.8-0.90.9-1.0-1.00.80.80.8-0.80.80.71.0
Vertical activity count, locomotor time 21.21.62.9-1.7-1.7-1.51.50.11.6-1.3-1.4-1.41.4-1.3-1.41.01.01.0-1.01.01.10.8
Light reinforcement 11.23.05.12.22.22.3-2.0-0.6-1.91.91.81.8-1.81.71.6-1.7-1.7-1.71.7-1.7-1.70.1
Light reinforcement 22.03.25.12.32.22.2-2.0-0.7-2.11.91.81.8-1.81.71.8-1.7-1.7-1.71.7-1.7-1.6-0.3
Bone: marrow area1.84.05.11.91.91.5-2.12.0-2.12.12.12.0-2.02.02.3-2.0-2.0-2.02.0-2.0-2.1-1.7
Bone: maximum diameter3.05.68.32.92.92.7-2.60.4-2.72.72.42.4-2.42.32.4-2.3-2.3-2.32.3-2.3-2.2-0.1
Bone: maximum force4.27.410.32.82.92.7-2.92.0-2.83.22.92.9-2.92.72.8-2.7-2.7-2.72.7-2.7-2.7-1.1
Bone: maximum moment3.05.38.12.52.52.3-2.51.8-2.52.82.42.4-2.42.22.4-2.2-2.2-2.22.2-2.2-2.2-0.3
Mean time between licks in bursts0.51.22.2-0.9-0.9-1.51.1-0.40.6-1.2-1.2-1.21.2-1.2-0.71.21.21.2-1.21.21.20.9
Mean num. licks in bursts3.35.15.9-2.3-2.3-2.32.4-1.22.3-2.4-2.4-2.42.4-2.3-2.32.32.32.3-2.32.32.41.1
Cd content in liver0.10.11.10.00.1-0.1-0.11.1-0.2-0.10.10.1-0.10.10.3-0.2-0.2-0.20.2-0.2-0.2-0.3
Co content in liver1.41.69.80.60.70.7-0.93.1-0.81.41.51.5-1.51.01.0-1.0-1.0-1.01.0-1.0-1.0-1.0
Cu content in liver0.70.81.7-1.2-1.2-1.11.01.31.1-0.5-0.6-0.60.6-0.9-0.90.90.90.9-0.90.90.9-0.5
Fe content in liver3.94.79.5-2.6-2.6-2.42.43.12.5-1.5-1.6-1.61.6-2.2-2.32.22.22.2-2.22.22.20.6
K content in liver0.40.33.6-0.2-0.20.2-0.11.90.20.40.40.4-0.40.40.1-0.4-0.4-0.40.4-0.4-0.4-1.1
Mg content in liver1.21.21.51.01.01.2-1.10.7-0.91.11.11.1-1.11.21.0-1.2-1.2-1.21.2-1.2-1.2-0.9
Mn content in liver0.10.10.7-0.4-0.3-0.50.20.70.1-0.3-0.4-0.40.4-0.20.00.20.20.2-0.20.20.1-0.8
Na content in liver0.50.56.6-0.7-0.7-0.40.42.60.70.40.30.3-0.3-0.0-0.30.00.00.0-0.00.00.1-0.6
Rb content in liver0.70.96.00.40.50.5-0.62.5-0.51.11.11.1-1.10.70.6-0.7-0.7-0.70.7-0.7-0.7-0.6
Se content in liver0.80.91.3-0.6-0.7-0.50.9-1.10.9-0.9-1.0-1.01.0-1.0-1.11.11.11.1-1.11.11.00.9
Sr content in liver1.41.22.31.51.51.3-1.3-0.1-1.40.90.90.9-0.91.11.1-1.1-1.1-1.11.1-1.1-1.10.2
Zn content in liver0.91.010.30.10.0-0.10.4-3.20.2-0.7-0.7-0.70.7-0.7-0.60.70.70.7-0.70.70.71.5
Bone: minimum diameter2.44.47.12.02.01.7-2.12.7-2.22.52.22.1-2.12.12.3-2.1-2.1-2.12.1-2.1-2.0-1.3
Time in familiar zone, hab. session 11.41.41.9-1.1-1.1-1.11.30.31.2-0.9-0.9-0.90.9-1.3-1.31.31.31.3-1.31.31.31.4
Time in novel zone, hab. session 10.50.52.50.90.80.7-0.7-1.6-0.80.20.20.2-0.20.60.7-0.6-0.6-0.60.6-0.6-0.6-0.4
Total zone transitions, hab. session 10.10.10.4-0.3-0.3-0.40.2-0.60.2-0.3-0.3-0.30.3-0.2-0.10.20.20.2-0.20.20.1-0.4
Total locomotion distance, hab. session 10.20.30.8-0.7-0.7-0.90.6-0.70.5-0.6-0.6-0.60.6-0.4-0.30.40.40.4-0.40.40.4-0.4
Locomotion velocity, hab. session 10.10.11.3-0.3-0.3-0.4-0.00.6-0.00.10.10.1-0.10.20.4-0.2-0.2-0.20.2-0.2-0.3-1.1
Time in familiar zone, hab. session 24.54.86.2-2.4-2.4-2.22.4-0.52.5-2.1-2.1-2.12.1-2.3-2.42.32.32.3-2.32.32.21.5
Time in novel zone, hab. session 25.45.58.83.02.92.7-2.7-0.9-2.82.12.12.1-2.12.32.5-2.3-2.3-2.32.3-2.3-2.3-0.6
Total zone transitions, hab. session 20.10.11.60.10.1-0.00.1-1.20.0-0.2-0.2-0.20.2-0.3-0.20.30.30.3-0.30.30.30.7
Total locomotion distance, hab. session 20.20.32.10.0-0.0-0.30.2-1.50.0-0.3-0.3-0.30.3-0.4-0.20.40.40.4-0.40.40.40.9
Locomotion velocity, hab. session 20.10.11.0-0.0-0.0-0.20.2-1.00.0-0.2-0.2-0.20.2-0.4-0.20.40.40.4-0.40.40.30.7
Novel to familiar place preference ratio0.00.00.2-0.3-0.3-0.20.10.40.2-0.1-0.1-0.10.10.0-0.1-0.0-0.0-0.00.0-0.0-0.1-0.4
Novelty place preference0.00.00.2-0.1-0.1-0.0-0.00.50.00.00.00.0-0.00.10.1-0.1-0.1-0.10.1-0.1-0.2-0.4
Time in novel zone, NPP test0.00.00.10.10.10.0-0.10.1-0.10.00.00.0-0.00.20.2-0.2-0.2-0.20.2-0.2-0.2-0.2
Total zone transitions, NPP test0.10.11.0-0.3-0.3-0.20.2-1.00.3-0.3-0.3-0.30.3-0.1-0.20.10.10.1-0.10.10.1-0.1
Total locomotion distance, NPP test0.40.61.2-0.9-0.9-0.80.8-1.10.9-0.8-0.8-0.80.8-0.7-0.80.70.70.7-0.70.70.70.3
Locomotion velocity, NPP test0.60.81.5-1.2-1.2-1.01.1-0.51.2-0.9-0.9-0.90.9-0.8-1.00.80.80.8-0.80.80.80.1
Intraocular pressure0.10.21.00.60.60.6-0.4-1.0-0.40.20.20.1-0.10.20.2-0.2-0.2-0.20.2-0.2-0.20.8
Delta distance traveled before/after self-admin0.50.61.00.60.61.0-0.70.4-0.40.80.80.8-0.80.80.5-0.9-0.9-0.90.9-0.9-0.8-0.8
Delta ambulatory time before/after self-admin0.10.10.3-0.4-0.4-0.10.30.10.5-0.2-0.2-0.20.2-0.2-0.40.10.10.1-0.10.10.2-0.0
Parametrial fat weight0.30.71.2-1.0-1.0-0.81.00.41.1-0.9-0.7-0.60.6-0.9-1.10.80.80.8-0.80.81.10.7
Pavlov. Cond. lever latency1.31.72.1-1.2-1.2-1.31.30.51.2-1.3-1.3-1.31.3-1.4-1.31.41.41.4-1.41.41.41.0
Pavlov. Cond. magazine entry latency1.11.44.3-0.9-1.0-1.11.1-2.10.9-1.3-1.3-1.31.3-1.1-1.01.11.11.1-1.11.11.11.0
Pavlov. Cond. change in total contacts0.10.11.4-0.0-0.00.1-0.1-1.2-0.1-0.2-0.2-0.20.20.30.2-0.3-0.3-0.30.3-0.3-0.3-0.6
Pavlov. Cond. index score0.10.11.7-0.2-0.2-0.10.0-1.30.1-0.2-0.2-0.20.20.10.0-0.1-0.1-0.10.1-0.1-0.1-0.2
Pavlov. Cond. latency score0.10.11.60.10.10.1-0.2-1.3-0.10.10.10.1-0.10.30.3-0.3-0.3-0.30.3-0.3-0.3-0.3
Pavlov. Cond. lever contacts1.01.21.50.90.91.0-1.1-0.3-1.01.11.11.1-1.11.21.1-1.2-1.2-1.21.2-1.2-1.2-0.9
Pavlov. Cond. magazine entry number1.21.51.91.21.21.3-1.21.4-1.21.41.41.4-1.41.21.1-1.2-1.2-1.21.2-1.2-1.2-0.7
Pavlov. Cond. intertrial magazine entries0.10.10.90.30.30.5-0.1-1.0-0.00.20.20.2-0.2-0.0-0.20.00.00.0-0.00.00.00.8
Pavlov. Cond. lever-magazine prob. diff.0.10.11.0-0.1-0.1-0.0-0.1-1.0-0.0-0.1-0.1-0.10.10.20.1-0.2-0.2-0.20.2-0.2-0.2-0.3
Pavlov. Cond. response bias0.10.20.8-0.4-0.4-0.40.4-0.90.4-0.5-0.5-0.50.5-0.3-0.30.30.30.3-0.30.30.30.3
Pavlov. Cond. lever latency0.20.30.70.60.60.8-0.6-0.2-0.40.50.80.5-0.50.60.4-0.6-0.6-0.60.6-0.6-0.60.3
Pavlov. Cond. magazine entry latency1.21.52.21.31.31.3-1.3-0.4-1.21.21.41.5-1.51.21.1-1.2-1.2-1.21.2-1.2-1.3-0.2
Pavlov. Cond. change in total contacts0.00.00.70.10.10.1-0.1-0.8-0.1-0.2-0.1-0.00.00.00.0-0.0-0.0-0.00.0-0.0-0.1-0.1
Pavlov. Cond. index score0.00.10.90.20.20.1-0.1-0.9-0.2-0.1-0.00.1-0.10.10.2-0.1-0.1-0.10.1-0.1-0.1-0.1
Pavlov. Cond. latency score0.00.00.50.20.20.1-0.1-0.7-0.2-0.0-0.00.1-0.10.10.2-0.1-0.1-0.10.1-0.1-0.1-0.2
Pavlov. Cond. lever contacts0.50.71.2-1.0-1.0-1.10.90.20.8-0.9-1.0-0.80.8-0.8-0.70.80.80.8-0.80.80.8-0.3
Pavlov. Cond. magazine entry number1.72.12.9-1.7-1.7-1.61.61.01.6-1.4-1.4-1.51.5-1.4-1.51.41.41.4-1.41.41.50.3
Pavlov. Cond. intertrial magazine entries0.30.51.1-0.9-0.9-1.00.70.30.6-0.7-0.7-0.60.6-0.6-0.50.60.60.6-0.60.60.6-0.6
Pavlov. Cond. lever-magazine prob. diff.0.10.10.90.30.30.2-0.2-1.0-0.30.00.10.2-0.20.20.2-0.2-0.2-0.20.2-0.2-0.2-0.1
Pavlov. Cond. response bias0.00.00.1-0.1-0.1-0.20.0-0.30.0-0.1-0.20.1-0.1-0.00.00.00.00.0-0.00.0-0.0-0.3
Time in closed arm before self-admin0.10.10.30.50.50.4-0.4-0.5-0.50.30.30.3-0.30.30.4-0.2-0.2-0.20.2-0.2-0.30.4
Time in closed arm after self-admin0.50.60.9-0.7-0.7-0.70.70.10.7-0.7-0.7-0.70.7-0.6-0.71.01.01.0-1.01.00.70.7
Time in open arm before self-admin0.20.20.30.50.50.4-0.50.4-0.60.50.50.5-0.50.40.6-0.5-0.5-0.50.5-0.5-0.5-0.4
Time in open arm after self-admin1.92.12.41.51.51.5-1.50.3-1.51.51.41.4-1.41.41.4-1.6-1.6-1.61.6-1.6-1.5-1.1
Bone: periosteal estimation4.810.212.93.23.23.0-3.32.6-3.33.63.43.3-3.33.33.4-3.3-3.3-3.33.3-3.3-3.2-1.7
Bone: periosteal perimeter5.59.411.03.03.02.9-3.22.1-3.13.33.33.3-3.33.23.2-3.2-3.2-3.23.2-3.2-3.2-1.9
Bone: post-yield work0.81.23.6-0.8-0.8-1.01.0-1.90.8-1.1-1.1-1.11.1-1.1-1.01.11.11.1-1.11.11.21.1
Progressive ratio test 1 active lever presses0.91.11.41.01.01.2-1.1-0.4-0.91.11.11.1-1.11.10.9-1.2-1.2-1.21.2-1.2-1.1-0.5
Progressive ratio test 1 breakpoint0.81.01.40.90.91.2-1.0-0.4-0.81.01.01.0-1.01.00.9-1.2-1.2-1.21.2-1.2-1.0-0.6
Progressive ratio test 1 inactive lever presses0.20.30.30.50.50.6-0.5-0.4-0.50.50.50.5-0.50.50.5-0.5-0.5-0.50.5-0.5-0.5-0.2
Progressive ratio test 2 active lever presses0.00.00.1-0.0-0.00.2-0.10.10.10.20.20.2-0.20.20.0-0.1-0.1-0.10.1-0.1-0.2-0.2
Progressive ratio test 2 breakpoint0.00.00.10.00.00.3-0.10.10.10.20.20.2-0.20.20.0-0.1-0.1-0.10.1-0.1-0.2-0.2
Progressive ratio test 2 inactive lever presses0.30.50.80.70.70.9-0.8-0.1-0.60.80.80.8-0.80.80.7-0.7-0.7-0.70.7-0.7-0.8-0.6
Incentive Sensitization - Responses0.10.20.4-0.4-0.4-0.20.40.50.5-0.2-0.2-0.20.2-0.2-0.40.60.60.6-0.60.60.20.2
Incentive Sensitization - Breakpoint0.10.10.3-0.4-0.4-0.20.30.50.4-0.2-0.2-0.20.2-0.2-0.30.50.50.5-0.50.50.20.2
Sum of active levers in priming session hrs 5-60.10.10.3-0.4-0.4-0.00.3-0.00.5-0.2-0.2-0.20.2-0.1-0.40.30.30.3-0.30.30.20.3
Progressive ratio0.30.40.60.50.50.6-0.60.8-0.50.60.70.7-0.70.60.6-0.6-0.6-0.60.6-0.6-0.7-0.6
Food seeking constrained by brief footshock2.53.14.41.71.71.7-1.9-0.5-1.81.21.81.7-1.71.91.9-1.9-1.9-1.91.9-1.9-1.7-2.1
Seeking ratio, punishment vs. effort0.10.11.00.20.20.1-0.3-1.0-0.3-0.20.10.1-0.10.30.4-0.3-0.3-0.30.3-0.3-0.1-0.5
Retroperitoneal fat weight0.41.72.41.11.11.5-1.20.7-0.91.41.21.3-1.31.31.0-1.5-1.5-1.51.5-1.5-1.2-1.5
Reaction time number correct0.51.04.01.51.50.7-1.0-2.0-1.50.50.60.5-0.50.51.0-0.5-0.5-0.50.5-0.5-0.51.6
Reaction time mean minus median0.61.42.1-1.4-1.4-1.41.4-0.81.3-1.4-1.2-1.11.1-1.3-1.21.11.11.1-1.11.11.10.3
Reaction time mean minus median AUC0.00.10.70.00.00.2-0.0-0.80.1-0.10.20.2-0.20.0-0.1-0.2-0.2-0.20.2-0.2-0.20.1
Reaction time num false alarms0.60.92.10.60.61.3-0.81.5-0.31.21.01.1-1.11.10.5-0.9-0.9-0.90.9-0.9-1.0-0.5
Reaction time num false alarms AUC0.71.12.60.90.91.6-1.00.8-0.51.41.21.2-1.21.20.6-1.1-1.1-1.11.1-1.1-1.2-0.3
Reaction time trials correct on left0.51.04.01.51.50.7-1.0-2.0-1.50.50.60.5-0.50.51.0-0.5-0.5-0.50.5-0.5-0.51.6
Reaction time trials on left0.50.94.31.41.40.6-0.9-2.1-1.40.40.50.4-0.40.40.9-0.4-0.4-0.40.4-0.4-0.41.7
Reaction time mean0.91.52.7-1.6-1.6-1.41.41.41.6-1.1-1.0-1.01.0-1.2-1.31.11.11.1-1.11.11.1-0.1
Reaction time mean AUC0.91.42.5-1.6-1.6-1.31.41.21.5-1.1-1.0-1.01.0-1.2-1.31.01.01.0-1.01.01.0-0.1
Median of all reaction times0.81.24.5-1.5-1.5-1.21.22.11.4-0.8-0.8-0.80.8-0.9-1.20.80.80.8-0.80.80.8-0.4
Reaction time omissions1.21.72.2-1.2-1.2-1.01.3-1.51.3-1.4-1.2-1.31.3-1.3-1.41.41.41.4-1.41.41.21.5
Reaction time false alarm rate0.40.62.90.10.11.1-0.41.70.30.90.70.8-0.80.80.0-0.7-0.7-0.70.7-0.7-0.8-0.9
Reaction time premature initiation rate0.10.10.8-0.2-0.20.10.2-0.90.4-0.2-0.2-0.20.2-0.2-0.40.30.30.3-0.30.30.20.6
Reaction time premature initiations0.20.43.90.50.50.4-0.2-2.0-0.30.00.10.0-0.0-0.10.00.10.10.1-0.10.10.01.5
Std. dev. reaction times0.71.32.1-1.4-1.4-1.11.3-0.51.4-1.2-1.1-1.01.0-1.2-1.41.01.01.0-1.01.01.10.6
Reaction time trials completed0.50.94.31.41.40.6-0.9-2.1-1.40.40.50.4-0.40.40.9-0.4-0.4-0.40.4-0.4-0.41.7
Reaction time trials AUC0.40.94.51.41.30.6-0.9-2.1-1.40.30.40.3-0.30.30.9-0.4-0.4-0.40.4-0.4-0.41.7
Run reversals in cocaine runway, females1.21.23.0-1.6-1.6-1.01.30.81.7-1.0-0.7-0.70.7-0.9-1.41.11.11.1-1.11.10.9-0.1
Run reversals in cocaine runway, males0.30.31.10.50.50.6-0.6-1.1-0.50.10.30.2-0.20.50.5-0.5-0.5-0.50.5-0.5-0.3-0.7
Latency to leave start box in cocaine runway1.01.21.91.01.01.2-1.01.1-0.81.41.41.4-1.41.00.8-1.0-1.0-1.01.0-1.0-1.3-0.1
Latency to leave start box in cocaine runway, F2.42.73.71.71.71.9-1.80.2-1.51.81.81.8-1.81.71.6-1.7-1.7-1.71.7-1.7-1.7-1.0
Latency to leave start box in cocaine runway, M0.20.21.8-0.2-0.2-0.10.31.30.30.30.20.2-0.2-0.4-0.40.40.40.4-0.40.4-0.21.0
Std. dev. time between licks in bursts0.10.10.6-0.1-0.0-0.3-0.10.5-0.30.10.10.1-0.10.20.4-0.2-0.2-0.20.2-0.2-0.2-0.8
Total sessions with >9 infusions0.10.10.20.20.20.4-0.30.0-0.20.40.40.4-0.40.40.2-0.3-0.3-0.30.3-0.3-0.4-0.2
Short access day 1 total inactive lever presses0.00.00.10.30.30.2-0.30.3-0.30.20.20.2-0.20.20.30.10.10.1-0.10.1-0.2-0.0
Short access day 10 total inactive lever presses0.40.91.6-0.7-0.7-1.30.9-0.40.5-1.1-1.1-1.11.1-1.1-0.71.01.01.0-1.01.01.10.7
Short access day 1 total infusions0.00.00.1-0.00.00.2-0.10.00.10.20.20.2-0.20.20.0-0.3-0.3-0.30.3-0.3-0.2-0.3
Short access day 10 total infusions0.00.00.10.10.10.1-0.1-0.2-0.10.10.10.1-0.10.10.1-0.1-0.1-0.10.1-0.1-0.10.3
Short access total infusions0.00.00.10.00.00.0-0.0-0.20.00.00.00.0-0.00.00.0-0.1-0.1-0.10.1-0.1-0.00.2
Short access day 1 locomotion0.40.50.60.70.70.8-0.70.0-0.70.70.70.7-0.70.70.7-0.8-0.8-0.80.8-0.8-0.7-0.6
Short access day 10 total locomotion1.32.33.2-1.6-1.6-1.81.7-0.21.5-1.6-1.6-1.61.6-1.6-1.51.51.51.5-1.51.51.61.2
Short access total locomotion0.50.60.8-0.8-0.8-0.90.8-0.10.8-0.8-0.8-0.80.8-0.8-0.80.90.90.9-0.90.90.80.8
One hour access (0.3 mA shock)0.10.10.10.30.30.2-0.3-0.4-0.30.20.20.2-0.20.20.3-0.3-0.3-0.30.3-0.3-0.2-0.1
Compulsive drug intake0.10.10.2-0.4-0.4-0.40.40.20.4-0.4-0.4-0.40.4-0.4-0.40.20.20.2-0.20.20.4-0.0
One hour access (shock baseline)0.00.00.10.20.20.2-0.2-0.4-0.20.20.20.2-0.20.20.2-0.2-0.2-0.20.2-0.2-0.20.0
Social response proportion1.51.72.2-1.0-1.1-1.41.3-1.11.0-1.4-1.5-1.41.4-1.4-1.11.31.31.3-1.31.31.51.3
Social responses0.20.21.50.40.3-0.10.0-1.1-0.4-0.2-0.3-0.20.2-0.30.00.40.40.4-0.40.40.41.2
Social time0.81.01.7-1.2-1.2-1.31.2-0.21.1-1.2-1.1-1.11.1-1.1-1.00.90.90.9-0.90.91.10.1
Soleus weight1.54.59.33.13.02.6-2.4-2.1-2.81.82.02.0-2.01.82.1-1.8-1.8-1.81.8-1.8-1.71.2
Bone: stiffness2.23.64.91.41.41.5-1.82.2-1.52.22.12.0-2.02.01.8-2.0-2.0-2.02.0-2.0-1.9-2.0
Tibialis anterior weight1.03.45.12.32.22.3-2.0-2.0-2.01.61.61.7-1.71.81.7-1.8-1.8-1.81.8-1.8-1.60.1
Time to tail flick, vehicle, before self-admin0.70.81.5-1.2-1.2-0.91.1-0.21.2-0.9-0.9-0.90.9-0.9-1.10.60.60.6-0.60.60.90.5
Time to tail flick, vehicle, after self-admin0.60.81.1-0.9-0.9-0.81.0-0.21.0-0.8-0.9-0.90.9-0.9-1.00.90.90.9-0.90.90.90.7
Time to tail flick, test, before self-admin0.10.10.20.40.40.3-0.3-0.1-0.40.20.30.3-0.30.30.3-0.0-0.0-0.00.0-0.0-0.20.1
Time to tail flick, test, after self-admin0.50.61.51.11.10.6-0.90.0-1.20.70.70.7-0.70.71.0-0.5-0.5-0.50.5-0.5-0.70.0
Delta time to tail flick, vehicle, before/after SA0.10.10.20.50.50.4-0.40.3-0.40.30.30.3-0.30.30.40.00.00.0-0.00.0-0.30.1
Delta time to tail flick, test, before/after SA0.00.00.10.30.3-0.1-0.1-0.0-0.40.10.00.0-0.0-0.10.2-0.1-0.1-0.10.1-0.1-0.00.3
Tibia length2.46.529.21.92.02.1-2.25.4-2.03.22.42.4-2.42.32.2-2.4-2.4-2.42.4-2.4-2.2-1.7
Ambulatory time before self-admin0.60.91.6-1.3-1.2-1.01.10.31.2-0.9-0.9-0.90.9-0.8-1.01.01.01.0-1.01.00.80.0
Ambulatory time after self-admin0.91.12.4-1.5-1.5-1.01.20.41.6-1.0-0.9-0.90.9-0.9-1.31.01.01.0-1.01.00.9-0.1
Bone: tissue strength1.51.53.31.81.71.1-1.41.1-1.81.31.11.1-1.11.01.5-1.0-1.0-1.01.0-1.0-0.90.4
Total heroin consumption0.40.40.80.90.90.8-0.8-0.4-0.90.50.60.6-0.60.80.8-0.4-0.4-0.40.4-0.4-0.60.5
Bone: trabecular number0.61.01.3-1.0-1.0-0.91.0-0.71.0-1.1-1.0-1.01.0-1.0-1.11.01.01.0-1.01.01.20.6
Bone: trabecular spacing2.22.93.61.81.81.6-1.81.7-1.91.91.71.6-1.61.71.8-1.7-1.7-1.71.7-1.7-1.6-1.1
Bone: trabecular thickness1.21.56.5-1.2-1.2-1.21.2-2.61.2-1.5-1.1-1.11.1-1.0-1.01.01.01.0-1.01.00.90.2
Bone: trabecular tissue density0.20.23.0-0.5-0.5-0.40.31.70.40.1-0.2-0.20.2-0.1-0.10.10.10.1-0.10.10.1-0.7
Water consumed over 24 hours0.60.81.7-0.6-0.6-1.30.80.30.3-0.9-0.9-0.90.9-1.0-0.41.01.01.0-1.01.01.00.7
Number of responses in last shaping day0.10.10.5-0.6-0.50.10.20.20.7-0.0-0.0-0.00.0-0.0-0.40.00.00.0-0.00.00.0-0.7