Hub : Genes

Gpx3

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain gene expression Gpx3 0.09 0.06 2.8e-08 0.07 0.08 0.06 0.07 4.9e-07 3.8e-08 1.0e-06 2.9e-07
2 Liver gene expression Gpx3 0.21 0.12 0.0e+00 0.19 0.2 0.19 0.19 3.8e-21 1.8e-21 9.8e-21 4.3e-21
3 NAcc gene expression Gpx3 0.08 0.06 2.8e-15 0.1 0.1 0.08 0.1 6.7e-15 8.8e-15 4.7e-12 3.5e-14
4 LHb gene expression Gpx3 0.16 0.15 5.0e-03 0.09 0.08 0.08 0.08 4.6e-03 6.3e-03 7.4e-03 6.9e-03
5 Adipose gene expression Gpx3 0.04 0.04 1.2e-03 0.02 0.01 0.01 0.02 2.4e-03 8.0e-03 4.4e-02 3.6e-03
6 Adipose mRNA stability Gpx3 0.14 0.14 3.1e-03 0.01 0 0 0 6.1e-02 1.2e-01 1.6e-01 7.8e-02
7 RMTg gene expression Gpx3 0.48 0.33 6.3e-05 0.16 0.15 0.15 0.14 5.5e-05 9.6e-05 1.0e-04 1.6e-04

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7
Bone: apparent density0.10.10.3-0.40.4-0.5-0.3-0.0-0.0-0.1
Area under the delay curve0.10.10.10.4-0.40.20.20.10.10.3
BMI with tail0.00.10.2-0.0-0.10.10.40.20.20.4
BMI without tail0.30.80.90.9-1.00.90.90.80.80.9
Body weight0.73.13.71.8-1.91.91.91.51.51.7
Weight adjusted by age0.00.10.20.2-0.20.20.20.40.40.1
Bone surface0.00.00.10.1-0.10.10.20.30.30.2
Bone volume0.30.40.8-0.80.8-0.9-0.6-0.4-0.4-0.6
Breakpoint value in progressive ratio session0.80.91.4-1.11.1-1.2-0.8-0.7-0.7-1.1
Number of licking bursts0.10.20.40.5-0.50.60.30.40.40.3
Context. condit. distance diff. score0.00.00.10.1-0.1-0.10.10.30.30.3
Locomotion velocity, session 10.10.10.1-0.10.1-0.2-0.3-0.3-0.3-0.2
Locomotion distance, session 10.30.30.40.6-0.60.50.60.50.50.6
Locomotion velocity, session 20.91.01.11.0-1.01.00.91.01.01.0
Locomotion distance, session 20.40.60.90.8-0.80.90.80.70.70.7
Locomotion velocity, session 33.03.43.71.8-1.81.71.81.91.91.9
Locomotion distance, session 32.32.53.01.6-1.61.41.51.71.71.7
Stereotopy head waving bouts, day 30.30.30.5-0.50.4-0.2-0.4-0.7-0.7-0.7
Stereotopy head waving duration, day 32.02.32.8-1.51.5-1.2-1.4-1.7-1.7-1.7
Locomotion velocity, session 70.00.00.0-0.10.1-0.10.10.10.10.2
Locomotion distance, session 70.10.10.2-0.40.4-0.3-0.3-0.4-0.4-0.4
Stereotopy head waving bouts, day 70.20.20.2-0.40.4-0.4-0.5-0.5-0.5-0.5
Stereotopy head waving duration, day 71.11.41.7-1.11.1-1.0-1.2-1.2-1.2-1.3
Locomotion velocity, session 82.53.03.41.7-1.71.61.61.81.81.8
Locomotion distance, session 80.91.21.41.1-1.11.01.11.11.11.2
Degree of sensitization distance3.33.44.0-1.81.8-1.7-1.6-2.0-2.0-2.0
Degree of sensitization stereotypy0.10.10.1-0.30.3-0.3-0.3-0.2-0.2-0.3
Conditioned locomotion0.40.50.70.8-0.80.80.80.50.50.6
Cocaine response after cond. corrected0.10.10.2-0.40.4-0.4-0.2-0.1-0.1-0.1
Cocaine response after cond. not corrected0.91.01.5-1.21.2-1.2-0.9-0.8-0.8-0.9
Cocaine response before conditioning2.42.93.3-1.81.8-1.8-1.6-1.6-1.6-1.7
Saline control response1.21.62.8-1.41.3-1.7-0.9-1.1-1.1-1.2
Bone: connectivity density0.00.00.1-0.20.2-0.2-0.2-0.1-0.1-0.1
Bone: cortical apparent density0.60.80.9-1.01.0-0.9-1.0-0.8-0.8-0.9
Bone: cortical area0.61.01.11.1-1.01.00.91.01.00.9
Bone: cortical porosity0.20.30.40.5-0.50.30.50.50.50.6
Bone: cortical porosity0.60.60.9-0.80.8-0.9-0.8-0.7-0.7-0.6
Bone: cortical thickness0.40.70.80.9-0.90.90.80.90.90.8
Bone: cortical thickness0.10.10.2-0.20.2-0.2-0.3-0.4-0.4-0.4
Bone: cortical tissue density0.81.01.2-1.11.1-1.1-1.1-0.9-0.9-1.0
Condit. Reinf. active minus inactive responses0.30.30.40.5-0.50.40.60.60.60.6
Condit. Reinf. active-inactive response ratio1.01.11.21.0-1.01.01.11.01.01.1
Condit. Reinf. active responses0.00.00.0-0.20.2-0.2-0.2-0.2-0.2-0.2
Condit. Reinf. inactive responses1.72.12.3-1.51.5-1.4-1.4-1.5-1.5-1.5
Incentive salience index mean1.31.61.81.3-1.31.31.31.31.31.3
Condit. Reinf. lever presses2.94.04.72.1-2.12.22.01.91.91.9
Condit. Reinf. active minus inactive responses0.70.91.6-1.11.1-1.3-0.7-0.7-0.7-0.8
Condit. Reinf. active-inactive response ratio0.10.10.10.1-0.10.10.30.30.30.3
Condit. Reinf. active responses1.82.53.2-1.71.7-1.8-1.5-1.5-1.5-1.5
Condit. Reinf. inactive responses4.15.35.8-2.32.3-2.4-2.3-2.3-2.3-2.3
Condit. Reinf. lever presses0.30.41.0-0.70.7-1.0-0.5-0.5-0.5-0.5
Condit. Reinf. lever reinforcers received1.72.43.6-1.71.7-1.9-1.4-1.3-1.3-1.4
Conditioned reinforcement - actives0.10.10.30.4-0.40.6-0.2-0.3-0.30.0
Conditioned reinforcement - inactives0.60.91.3-0.70.7-0.5-1.1-1.1-1.1-0.9
Conditioned locomotion0.20.30.6-0.40.4-0.2-0.6-0.6-0.6-0.8
Patch foraging indifference point 0 sec3.15.76.5-2.62.5-2.4-2.3-2.3-2.3-2.3
Patch foraging indifference point AUC0.00.00.1-0.10.0-0.10.30.20.20.0
Delay disc. indifference point, 0s delay0.00.00.00.1-0.0-0.10.10.10.1-0.0
Delay disc. indifference point, 16s delay0.00.00.1-0.20.1-0.2-0.3-0.3-0.3-0.1
Delay disc. indifference point, 2s delay1.11.21.61.1-1.21.01.01.01.01.2
Delay disc. indifference point, 24s delay0.00.00.10.2-0.20.2-0.0-0.1-0.10.2
Delay disc. indifference point, 4s delay1.31.31.5-1.01.1-1.2-1.2-1.2-1.2-1.2
Delay disc. indifference point, 8s delay0.40.40.60.8-0.70.70.60.50.50.7
Indifference point function ln k0.20.40.70.7-0.70.80.60.50.50.7
Indifference point function log k0.20.40.70.7-0.70.80.60.50.50.7
Patch foraging total patch changes 0 sec3.26.06.8-2.62.6-2.5-2.4-2.3-2.3-2.4
Patch foraging total patch changes 12 sec5.47.07.9-2.82.8-2.8-2.5-2.5-2.5-2.6
Patch foraging total patch changes 18 sec1.52.33.1-1.71.7-1.8-1.4-1.2-1.2-1.5
Patch foraging total patch changes 24 sec2.84.87.6-2.52.4-2.8-1.9-1.7-1.7-2.1
Patch foraging total patch changes 6 sec4.36.57.0-2.72.6-2.6-2.5-2.5-2.5-2.5
Patch foraging time to switch 0 sec0.50.91.5-0.80.9-0.9-1.2-1.0-1.0-0.9
Patch foraging water rate 0 sec0.40.91.20.9-1.01.01.10.80.81.0
Patch foraging water rate 12 sec0.20.50.70.7-0.70.70.90.60.60.5
Patch foraging water rate 18 sec1.11.72.1-1.21.2-1.2-1.2-1.5-1.5-1.3
Patch foraging water rate 24 sec0.40.50.8-0.90.8-0.9-0.5-0.5-0.5-0.8
Patch foraging water rate 6 sec1.72.43.01.6-1.61.61.71.51.51.3
Seeking ratio, delayed vs. immediate footshock0.60.71.1-1.01.0-1.1-0.5-0.5-0.5-1.0
Distance traveled before self-admin1.92.53.11.5-1.61.81.61.61.61.5
Distance traveled after self-admin0.10.10.10.2-0.20.30.30.30.30.2
Extensor digitorum longus weight0.31.21.3-1.11.1-1.2-1.0-1.0-1.0-1.1
Bone: elastic displacement0.00.00.0-0.10.1-0.20.00.10.10.1
Bone: elastic work0.60.80.90.9-0.90.70.91.01.01.0
Bone: endosteal estimation0.61.21.41.2-1.11.21.11.01.01.0
Bone: endosteal perimeter0.81.82.31.5-1.51.51.31.11.11.3
Epididymis fat weight0.20.61.00.7-0.70.60.81.01.00.7
Delta time in closed arm before/after self-admin0.20.20.3-0.40.4-0.40.40.50.5-0.4
Delta time in open arm before/after self-admin0.20.20.50.5-0.50.70.20.10.10.4
Diff in mean of infusions in LGA sessions0.10.10.2-0.20.1-0.20.30.40.40.1
Delay discount exponential model param0.00.10.1-0.30.3-0.2-0.1-0.1-0.1-0.3
Extinction: sum of active levers before priming0.10.10.20.1-0.20.30.40.40.4-0.0
Active lever presses in extinction session 61.41.41.7-1.31.3-1.3-1.2-1.1-1.1-1.1
Bone: final force1.52.42.51.6-1.61.51.51.51.51.5
Bone: final moment1.42.22.31.5-1.51.51.51.51.51.4
Food consumed during 24 hour testing period5.98.18.42.8-2.82.82.92.92.92.8
Glucose0.00.10.10.2-0.20.20.30.30.30.3
Heart weight1.52.33.71.8-1.81.91.01.01.01.7
Delay discount hyperbolic model param0.00.00.0-0.20.2-0.10.00.10.1-0.1
Intermittent access intake day 1-15 change0.51.01.6-0.60.7-0.7-1.1-1.3-1.3-1.2
Intermittent access intake escalation0.51.11.5-0.70.8-0.9-1.1-1.2-1.2-1.2
Intermittent access intake escalation 21.92.22.7-1.21.3-1.4-1.5-1.6-1.6-1.6
Intermitt. access day 1 inactive lever presses0.10.40.6-0.70.7-0.8-0.6-0.5-0.5-0.6
Intermitt. access day 15 inactive lever presses0.00.00.0-0.10.1-0.0-0.1-0.1-0.1-0.0
Intermitt. access escalation Index0.10.10.20.3-0.40.50.10.10.10.5
Intermittent access day 1 total infusions0.10.10.20.5-0.50.40.30.30.30.3
Intermittent access day 15 total infusions0.10.20.30.00.0-0.1-0.5-0.6-0.6-0.5
Intermittent access terminal intake (last 3 days)0.30.40.8-0.20.2-0.2-0.8-0.9-0.9-0.7
Intermittent access total infusions0.10.10.20.4-0.30.4-0.2-0.2-0.2-0.1
Intermittent access day 1 locomotion0.00.00.10.3-0.20.00.10.10.10.0
Intermittent access day 15 total locomotion2.85.26.2-2.02.1-2.0-2.5-2.5-2.5-2.2
Intermittent access total locomotion2.83.44.2-1.71.7-1.6-1.9-1.9-1.9-2.0
Intermittent access standard deviation0.20.50.80.8-0.70.40.80.90.90.4
Left kidney weight5.324.827.35.0-5.14.85.24.94.94.9
Right kidney weight4.319.821.74.7-4.74.64.34.24.24.5
Cocaine induced anxiety0.10.20.4-0.10.1-0.1-0.6-0.7-0.7-0.2
Post-drug Anxiety0.20.20.3-0.40.5-0.2-0.5-0.5-0.5-0.4
Baseline Anxiety0.80.91.30.6-0.61.11.11.11.10.8
Tail length1.14.35.22.3-2.22.01.92.12.11.9
Length with tail1.04.35.62.4-2.32.21.81.81.81.9
Length without tail0.30.91.41.0-1.11.21.00.70.70.9
Times rat made contact with spout1.11.21.71.1-1.11.31.01.11.11.0
Lifetime Intake0.30.40.90.9-0.80.90.40.30.30.4
Liver weight, left0.10.20.3-0.40.4-0.5-0.3-0.5-0.5-0.4
Liver weight, right0.00.00.00.1-0.1-0.10.20.10.10.1
Locomotor activity1.72.63.3-1.51.5-1.3-1.8-1.8-1.8-1.5
Locomotor testing distance3.36.06.4-2.52.5-2.5-2.4-2.5-2.5-2.2
Locomotor testing rearing2.14.15.2-2.22.1-2.3-1.8-2.0-2.0-1.7
Locomotion in novel chamber0.00.10.2-0.20.2-0.2-0.4-0.2-0.2-0.3
Locomotion in novel chamber post-restriction0.10.10.4-0.40.3-0.60.00.00.0-0.3
Fecal boli incidents, locomotor time 10.10.10.2-0.40.4-0.40.10.20.2-0.1
Change in fecal boli incidents, locomotor task1.11.12.11.4-1.31.40.70.60.60.9
Time >=10cm from walls, locomotor time 13.53.74.0-2.02.0-2.0-1.9-1.8-1.8-1.9
Bouts of movement, locomotor time 10.30.30.5-0.70.7-0.6-0.5-0.4-0.4-0.5
Total resting periods, locomotor time 10.20.20.4-0.70.6-0.6-0.4-0.3-0.3-0.5
Rest time, locomotor task time 10.30.30.6-0.70.7-0.7-0.4-0.3-0.3-0.7
Distance moved, locomotor task time 10.10.10.10.4-0.40.1-0.3-0.4-0.40.3
Vertical activity count, locomotor time 10.30.81.4-0.60.6-0.7-1.1-1.2-1.2-0.6
Time >=10cm from walls, locomotor time 20.00.00.0-0.10.1-0.10.00.10.10.1
Bouts of movement, locomotor time 20.10.20.3-0.30.3-0.4-0.5-0.6-0.6-0.4
Total resting periods, locomotor time 20.10.20.3-0.30.3-0.5-0.5-0.5-0.5-0.4
Rest time, locomotor task time 21.82.32.5-1.61.6-1.6-1.5-1.4-1.4-1.4
Distance moved, locomotor task time 20.00.10.1-0.20.1-0.3-0.3-0.3-0.3-0.0
Vertical activity count, locomotor time 20.10.10.1-0.20.2-0.3-0.3-0.3-0.3-0.2
Light reinforcement 10.92.13.0-1.71.7-1.6-1.3-1.2-1.2-1.4
Light reinforcement 20.00.00.1-0.10.0-0.30.10.10.10.2
Bone: marrow area0.71.51.71.3-1.31.31.21.21.21.2
Bone: maximum diameter1.52.83.31.8-1.81.81.61.51.51.6
Bone: maximum force0.61.01.11.0-1.01.01.01.01.00.9
Bone: maximum moment0.50.90.91.0-1.00.91.00.90.90.9
Mean time between licks in bursts1.43.43.51.9-1.81.91.81.91.91.8
Mean num. licks in bursts0.00.10.1-0.30.3-0.3-0.2-0.2-0.2-0.1
Cd content in liver1.82.02.4-1.41.3-1.4-1.4-1.5-1.5-1.4
Co content in liver0.10.10.30.4-0.40.50.1-0.2-0.20.2
Cu content in liver0.00.00.00.2-0.20.2-0.0-0.0-0.00.2
Fe content in liver0.00.00.00.1-0.10.1-0.1-0.0-0.00.2
K content in liver12.111.612.53.4-3.43.43.53.43.43.2
Mg content in liver2.52.53.01.6-1.61.51.71.61.61.5
Mn content in liver0.00.10.2-0.10.1-0.0-0.0-0.3-0.3-0.4
Na content in liver1.61.72.11.3-1.31.31.31.41.41.2
Rb content in liver1.51.82.5-1.41.4-1.6-1.4-1.2-1.2-1.1
Se content in liver1.72.02.21.5-1.41.51.31.41.41.4
Sr content in liver0.00.00.1-0.0-0.00.00.20.10.1-0.1
Zn content in liver0.50.50.70.9-0.90.70.80.60.60.8
Bone: minimum diameter1.01.92.31.5-1.51.51.31.31.31.3
Time in familiar zone, hab. session 18.27.98.7-2.92.9-2.7-2.9-2.8-2.8-2.7
Time in novel zone, hab. session 15.25.25.62.2-2.22.12.42.42.42.3
Total zone transitions, hab. session 10.10.10.1-0.30.3-0.3-0.3-0.3-0.3-0.3
Total locomotion distance, hab. session 10.60.80.9-0.90.9-0.8-0.9-0.9-0.9-0.9
Locomotion velocity, hab. session 10.20.20.3-0.40.4-0.4-0.4-0.6-0.6-0.5
Time in familiar zone, hab. session 21.51.61.7-1.31.3-1.2-1.3-1.2-1.2-1.3
Time in novel zone, hab. session 23.53.63.81.9-1.91.81.91.91.91.9
Total zone transitions, hab. session 20.10.10.10.2-0.20.10.20.40.40.3
Total locomotion distance, hab. session 20.20.30.4-0.50.5-0.6-0.6-0.4-0.4-0.4
Locomotion velocity, hab. session 20.00.00.1-0.20.2-0.2-0.3-0.1-0.1-0.1
Novel to familiar place preference ratio0.30.30.4-0.60.5-0.6-0.4-0.5-0.5-0.5
Novelty place preference0.10.20.2-0.40.4-0.5-0.3-0.4-0.4-0.4
Time in novel zone, NPP test0.10.10.2-0.40.4-0.5-0.3-0.4-0.4-0.4
Total zone transitions, NPP test0.10.10.1-0.30.3-0.3-0.4-0.3-0.3-0.4
Total locomotion distance, NPP test0.10.20.2-0.40.4-0.4-0.4-0.4-0.4-0.5
Locomotion velocity, NPP test0.10.20.2-0.40.4-0.4-0.4-0.4-0.4-0.4
Intraocular pressure0.10.20.3-0.40.4-0.2-0.5-0.4-0.4-0.3
Delta distance traveled before/after self-admin1.51.62.0-1.31.3-1.4-1.2-1.2-1.2-1.2
Delta ambulatory time before/after self-admin1.92.42.7-1.61.6-1.6-1.4-1.4-1.4-1.5
Parametrial fat weight2.14.95.32.2-2.32.02.32.22.22.2
Pavlov. Cond. lever latency0.30.40.6-0.70.7-0.8-0.5-0.6-0.6-0.6
Pavlov. Cond. magazine entry latency0.10.20.40.5-0.50.60.30.30.30.4
Pavlov. Cond. change in total contacts0.00.00.10.2-0.10.3-0.1-0.0-0.00.1
Pavlov. Cond. index score0.20.30.50.6-0.60.70.40.40.40.5
Pavlov. Cond. latency score0.30.40.70.7-0.70.80.50.50.50.6
Pavlov. Cond. lever contacts0.30.30.60.7-0.60.80.50.50.50.6
Pavlov. Cond. magazine entry number0.00.00.1-0.20.1-0.3-0.0-0.1-0.1-0.2
Pavlov. Cond. intertrial magazine entries1.61.92.1-1.41.4-1.4-1.2-1.4-1.4-1.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.5-0.40.50.20.20.20.3
Pavlov. Cond. response bias0.10.10.20.3-0.30.40.10.20.20.2
Pavlov. Cond. lever latency0.71.01.3-0.80.9-0.7-1.1-1.1-1.1-1.2
Pavlov. Cond. magazine entry latency0.70.81.00.9-0.90.90.80.90.91.0
Pavlov. Cond. change in total contacts0.00.00.00.0-0.10.00.10.10.10.2
Pavlov. Cond. index score0.60.81.00.8-0.80.80.90.90.91.0
Pavlov. Cond. latency score0.71.01.20.9-0.90.91.01.01.01.1
Pavlov. Cond. lever contacts0.60.91.30.8-0.80.71.01.11.11.1
Pavlov. Cond. magazine entry number0.00.10.1-0.20.2-0.2-0.2-0.2-0.2-0.3
Pavlov. Cond. intertrial magazine entries2.63.94.3-2.02.0-2.0-1.9-1.9-1.9-2.1
Pavlov. Cond. lever-magazine prob. diff.0.50.70.90.8-0.80.80.90.90.91.0
Pavlov. Cond. response bias1.01.41.91.1-1.10.91.21.31.31.4
Time in closed arm before self-admin0.50.61.20.9-0.90.70.60.50.51.1
Time in closed arm after self-admin0.70.81.50.5-0.50.41.11.21.20.7
Time in open arm before self-admin0.30.30.7-0.50.6-0.5-0.6-0.5-0.5-0.8
Time in open arm after self-admin0.80.91.4-0.60.7-0.4-1.2-1.2-1.2-1.0
Bone: periosteal estimation1.02.12.31.5-1.51.51.51.41.41.3
Bone: periosteal perimeter0.81.31.71.3-1.31.31.11.01.01.1
Bone: post-yield work0.81.21.3-1.11.1-1.0-1.1-1.1-1.1-1.2
Progressive ratio test 1 active lever presses0.20.30.6-0.10.1-0.2-0.7-0.7-0.7-0.6
Progressive ratio test 1 breakpoint0.30.40.8-0.20.2-0.3-0.8-0.9-0.9-0.7
Progressive ratio test 1 inactive lever presses0.30.51.20.9-0.81.10.40.40.40.6
Progressive ratio test 2 active lever presses0.30.30.5-0.30.3-0.1-0.7-0.7-0.7-0.7
Progressive ratio test 2 breakpoint0.40.50.8-0.50.5-0.3-0.8-0.9-0.9-0.8
Progressive ratio test 2 inactive lever presses0.10.10.3-0.10.2-0.2-0.5-0.5-0.5-0.3
Incentive Sensitization - Responses0.81.11.3-1.01.0-0.6-1.1-1.2-1.2-1.0
Incentive Sensitization - Breakpoint0.60.81.0-0.90.9-0.6-1.0-1.0-1.0-0.9
Sum of active levers in priming session hrs 5-60.10.10.1-0.40.3-0.2-0.2-0.2-0.2-0.3
Progressive ratio0.40.71.0-0.70.7-0.6-1.0-1.0-1.0-0.8
Food seeking constrained by brief footshock0.10.10.2-0.40.3-0.4-0.0-0.3-0.3-0.3
Seeking ratio, punishment vs. effort0.60.81.60.7-0.70.51.31.11.10.8
Retroperitoneal fat weight1.14.55.62.1-2.11.72.42.12.12.3
Reaction time number correct0.51.01.2-1.11.1-1.1-0.9-0.9-0.9-0.9
Reaction time mean minus median0.10.10.30.6-0.50.50.10.00.00.3
Reaction time mean minus median AUC0.10.20.40.00.00.0-0.5-0.6-0.6-0.2
Reaction time num false alarms0.30.40.7-0.50.5-0.4-0.8-0.8-0.8-0.6
Reaction time num false alarms AUC0.71.11.9-0.80.8-0.6-1.2-1.4-1.4-0.9
Reaction time trials correct on left0.51.01.2-1.11.1-1.1-0.9-0.9-0.9-0.9
Reaction time trials on left0.50.91.2-1.11.0-1.0-0.9-0.9-0.9-0.9
Reaction time mean1.32.12.31.5-1.51.41.31.51.51.4
Reaction time mean AUC1.01.62.01.4-1.41.31.11.21.21.2
Median of all reaction times2.02.93.21.7-1.71.71.61.81.81.7
Reaction time omissions0.50.71.11.0-1.00.80.70.60.60.8
Reaction time false alarm rate0.10.10.20.1-0.10.2-0.4-0.5-0.5-0.1
Reaction time premature initiation rate0.60.91.4-1.11.0-1.0-0.8-0.7-0.7-1.2
Reaction time premature initiations1.22.12.7-1.61.6-1.6-1.3-1.2-1.2-1.7
Std. dev. reaction times0.00.00.10.3-0.30.2-0.1-0.1-0.10.1
Reaction time trials completed0.50.91.2-1.11.0-1.0-0.9-0.9-0.9-0.9
Reaction time trials AUC0.61.21.6-1.31.2-1.2-1.0-1.0-1.0-1.0
Run reversals in cocaine runway, females0.20.20.30.5-0.50.60.10.20.20.6
Run reversals in cocaine runway, males0.00.00.1-0.20.20.1-0.2-0.2-0.2-0.2
Latency to leave start box in cocaine runway0.80.91.61.2-1.10.81.00.90.90.7
Latency to leave start box in cocaine runway, F1.82.12.71.6-1.61.51.21.41.41.3
Latency to leave start box in cocaine runway, M0.10.10.20.3-0.2-0.20.40.00.0-0.2
Std. dev. time between licks in bursts1.72.32.51.5-1.51.41.61.61.61.6
Total sessions with >9 infusions0.10.20.60.6-0.50.70.20.10.1-0.0
Short access day 1 total inactive lever presses2.83.75.3-1.71.8-1.8-1.9-1.9-1.9-2.3
Short access day 10 total inactive lever presses0.20.40.60.5-0.50.30.70.70.70.7
Short access day 1 total infusions0.20.20.70.6-0.60.80.20.10.10.2
Short access day 10 total infusions0.10.10.20.3-0.30.50.00.00.0-0.2
Short access total infusions0.60.71.71.1-1.01.30.60.50.50.6
Short access day 1 locomotion0.40.50.8-0.60.6-0.2-0.7-0.8-0.8-0.9
Short access day 10 total locomotion0.00.00.0-0.10.1-0.0-0.1-0.0-0.0-0.2
Short access total locomotion0.10.10.20.00.00.2-0.3-0.3-0.3-0.5
One hour access (0.3 mA shock)0.30.40.9-0.10.2-0.4-0.8-0.9-0.9-0.3
Compulsive drug intake0.20.31.00.5-0.50.30.30.30.31.0
One hour access (shock baseline)0.71.01.6-0.70.7-0.6-1.2-1.3-1.3-1.2
Social response proportion0.00.00.10.0-0.1-0.0-0.0-0.4-0.40.2
Social responses1.11.42.1-1.31.2-1.1-1.0-1.4-1.4-0.8
Social time2.94.05.4-1.91.8-1.9-1.9-2.3-2.3-1.9
Soleus weight0.51.51.61.2-1.31.21.31.21.21.2
Bone: stiffness0.00.00.10.3-0.30.40.1-0.0-0.00.1
Tibialis anterior weight0.82.63.3-1.71.7-1.8-1.5-1.5-1.5-1.6
Time to tail flick, vehicle, before self-admin0.60.70.90.8-0.90.90.70.70.71.0
Time to tail flick, vehicle, after self-admin0.50.70.80.8-0.90.90.80.70.70.9
Time to tail flick, test, before self-admin0.20.20.5-0.30.3-0.0-0.6-0.7-0.7-0.1
Time to tail flick, test, after self-admin0.50.51.0-0.50.5-0.6-0.9-1.0-1.0-0.2
Delta time to tail flick, vehicle, before/after SA0.40.40.5-0.60.6-0.7-0.6-0.6-0.6-0.7
Delta time to tail flick, test, before/after SA0.00.00.00.2-0.20.1-0.0-0.1-0.10.2
Tibia length0.41.21.41.2-1.21.21.01.01.01.0
Ambulatory time before self-admin1.31.92.31.2-1.31.51.51.51.51.3
Ambulatory time after self-admin0.10.10.2-0.0-0.00.10.40.50.50.1
Bone: tissue strength0.30.30.30.5-0.60.50.60.50.50.6
Total heroin consumption1.21.41.9-1.41.3-1.4-1.1-1.0-1.0-1.1
Bone: trabecular number0.10.10.4-0.50.5-0.6-0.4-0.1-0.1-0.1
Bone: trabecular spacing0.00.00.0-0.00.00.0-0.1-0.2-0.2-0.1
Bone: trabecular thickness0.00.00.0-0.10.0-0.10.1-0.1-0.1-0.1
Bone: trabecular tissue density0.00.00.0-0.10.1-0.2-0.10.00.0-0.1
Water consumed over 24 hours2.83.75.22.0-2.02.31.81.81.81.8
Number of responses in last shaping day0.60.71.5-0.20.2-0.0-1.1-1.2-1.2-0.6