Hub : Genes

Gps1

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose gene expression Gps1 0.02 0.02 9.0e-03 0 0.01 0 0.01 8.4e-02 1.4e-02 1.8e-01 5.2e-02
2 BLA gene expression Gps1 0.07 0.06 1.4e-03 0.03 0.04 0.03 0.04 1.5e-02 5.4e-03 1.6e-02 4.4e-03
3 NAcc gene expression Gps1 0.03 0.02 8.3e-04 0.03 0.02 0.02 0.02 2.1e-04 8.7e-04 1.3e-03 8.7e-04
4 BLA isoform ratio XM_008768463.2 0.1 0.07 1.1e-03 0.06 0.02 0.04 0.03 4.2e-04 1.8e-02 4.9e-03 7.6e-03
5 BLA intron excision ratio chr10_106053123_106053314 0.07 0.05 5.9e-03 0.05 0.03 0.04 0.04 1.2e-03 1.5e-02 5.4e-03 3.5e-03
6 BLA intron excision ratio chr10_106053123_106053317 0.07 0.05 6.8e-03 0.05 0.03 0.03 0.04 1.3e-03 1.2e-02 1.0e-02 2.9e-03
7 RMTg intron excision ratio chr10_106053123_106053314 0.12 0.08 9.7e-03 0.1 0.03 0.03 0.04 9.3e-04 5.8e-02 4.9e-02 4.1e-02
8 PL gene expression Gps1 0.03 0.03 2.8e-03 0.01 0.02 0.01 0 3.6e-02 1.4e-03 3.5e-02 9.7e-02
9 Brain gene expression Gps1 0.04 0.03 1.3e-03 0.02 0.02 0.02 0.02 6.2e-03 3.1e-03 4.6e-03 2.2e-03
10 BLA isoform ratio NM_001270939.1 0.09 0.06 1.8e-03 0.04 0.03 0.02 0.02 4.5e-03 1.0e-02 1.9e-02 2.5e-02
11 OFC gene expression Gps1 0.18 0.11 5.1e-03 0.04 -0.01 0.04 0.01 4.8e-02 4.7e-01 4.4e-02 2.3e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11
Bone: apparent density0.10.10.4-0.3-0.40.50.1-0.10.1-0.0-0.6-0.5-0.20.5
Area under the delay curve1.11.11.91.31.4-1.30.6-0.60.6-1.11.41.0-0.9-0.9
BMI with tail0.30.82.5-1.5-1.61.4-0.30.3-0.30.2-0.9-0.90.8-0.2
BMI without tail3.36.818.9-2.9-3.34.4-0.10.1-0.10.4-4.3-3.90.91.7
Body weight2.610.821.0-4.3-4.64.1-2.82.8-2.82.5-3.6-3.52.50.5
Weight adjusted by age2.32.65.3-1.8-2.31.4-1.81.8-1.81.5-1.3-1.31.5-0.3
Bone surface0.20.30.8-0.5-0.60.5-0.40.4-0.40.5-0.8-0.90.30.6
Bone volume0.20.30.7-0.5-0.60.5-0.30.3-0.30.3-0.8-0.80.10.7
Breakpoint value in progressive ratio session1.11.22.5-1.0-0.60.1-1.61.6-1.61.6-0.10.21.30.7
Number of licking bursts0.10.20.3-0.1-0.30.40.4-0.40.4-0.3-0.5-0.5-0.50.2
Context. condit. distance diff. score1.01.23.4-0.1-0.61.11.1-1.11.1-1.0-1.2-1.8-0.81.1
Locomotion velocity, session 11.21.33.91.11.5-1.80.1-0.10.1-0.12.01.30.3-1.3
Locomotion distance, session 12.83.55.02.12.2-1.62.1-2.12.1-2.21.71.1-2.2-0.5
Locomotion velocity, session 23.33.86.92.32.6-2.51.4-1.41.4-1.52.62.3-1.7-1.1
Locomotion distance, session 20.81.12.10.90.9-0.31.4-1.41.4-1.40.50.1-1.4-0.2
Locomotion velocity, session 31.11.23.61.31.5-1.70.4-0.40.4-0.31.91.4-0.6-0.3
Locomotion distance, session 32.32.54.81.92.1-2.11.1-1.11.1-1.22.21.9-1.4-0.3
Stereotopy head waving bouts, day 30.30.41.20.60.8-1.00.1-0.10.1-0.01.10.80.10.2
Stereotopy head waving duration, day 30.20.30.70.50.6-0.80.3-0.30.3-0.20.80.6-0.10.7
Locomotion velocity, session 70.70.71.11.11.1-1.10.7-0.70.7-0.70.90.7-1.0-0.5
Locomotion distance, session 73.44.36.52.32.2-1.72.6-2.62.6-2.31.50.9-2.4-0.5
Stereotopy head waving bouts, day 70.10.10.3-0.4-0.50.3-0.30.3-0.30.0-0.3-0.20.20.6
Stereotopy head waving duration, day 70.30.40.7-0.7-0.80.5-0.70.7-0.70.4-0.5-0.20.50.7
Locomotion velocity, session 81.11.32.60.90.9-0.21.6-1.61.6-1.50.4-0.0-1.5-0.8
Locomotion distance, session 81.72.54.60.50.00.82.2-2.22.2-2.1-0.8-1.6-1.91.0
Degree of sensitization distance0.50.51.6-0.4-0.71.00.5-0.50.5-0.2-1.2-1.3-0.1-0.1
Degree of sensitization stereotypy0.30.30.7-0.7-0.80.7-0.40.4-0.40.1-0.6-0.40.30.5
Conditioned locomotion2.42.87.1-2.0-2.32.6-0.70.7-0.70.7-2.7-2.30.60.7
Cocaine response after cond. corrected0.20.20.5-0.10.2-0.2-0.60.6-0.60.50.40.30.5-0.7
Cocaine response after cond. not corrected0.30.30.80.50.8-0.7-0.00.0-0.00.00.80.9-0.0-0.9
Cocaine response before conditioning1.11.32.21.31.2-0.91.2-1.21.2-1.20.81.3-1.5-0.0
Saline control response2.12.75.2-2.0-2.22.3-1.31.3-1.31.3-2.3-1.51.00.8
Bone: connectivity density0.30.40.90.40.20.10.9-0.90.9-0.9-0.3-0.4-0.90.4
Bone: cortical apparent density1.62.24.41.81.9-2.11.0-1.01.0-1.02.11.8-0.7-0.3
Bone: cortical area4.87.213.7-3.7-3.42.9-2.82.8-2.82.8-2.1-2.12.3-0.6
Bone: cortical porosity2.93.26.8-1.5-1.10.4-2.62.6-2.62.5-0.10.32.1-0.6
Bone: cortical porosity2.62.95.8-1.6-1.30.6-2.42.4-2.42.3-0.4-0.12.0-0.4
Bone: cortical thickness4.98.014.8-3.8-3.32.6-3.23.2-3.23.2-1.5-1.62.9-1.4
Bone: cortical thickness1.72.03.9-2.0-1.61.3-1.51.5-1.51.6-0.6-0.71.4-1.3
Bone: cortical tissue density1.92.55.12.02.1-2.31.1-1.11.1-1.02.21.9-0.8-0.3
Condit. Reinf. active minus inactive responses1.82.04.6-1.7-1.81.8-1.01.0-1.00.8-1.8-2.10.8-0.6
Condit. Reinf. active-inactive response ratio0.70.81.7-1.1-1.11.0-0.80.8-0.80.5-1.0-1.30.4-0.5
Condit. Reinf. active responses3.13.89.0-2.2-2.52.6-1.31.3-1.31.0-2.6-3.01.2-0.5
Condit. Reinf. inactive responses0.91.12.6-1.1-1.31.5-0.50.5-0.50.5-1.5-1.60.7-0.2
Incentive salience index mean1.31.64.5-1.4-1.61.7-0.80.8-0.80.5-1.7-2.10.5-0.7
Condit. Reinf. lever presses0.20.30.70.30.00.10.5-0.50.5-0.8-0.4-0.6-0.8-0.6
Condit. Reinf. active minus inactive responses0.60.71.7-1.2-1.11.3-0.50.5-0.50.3-1.0-1.20.70.3
Condit. Reinf. active-inactive response ratio2.22.33.7-1.9-1.81.7-1.41.4-1.41.3-1.4-1.61.60.3
Condit. Reinf. active responses0.20.20.7-0.6-0.50.80.1-0.10.1-0.2-0.6-0.80.10.1
Condit. Reinf. inactive responses0.50.70.90.80.9-0.71.0-1.01.0-1.00.60.4-0.9-0.4
Condit. Reinf. lever presses0.10.20.5-0.3-0.40.70.3-0.30.3-0.4-0.7-0.7-0.40.0
Condit. Reinf. lever reinforcers received0.20.20.8-0.5-0.50.80.2-0.20.2-0.4-0.6-0.9-0.10.3
Conditioned reinforcement - actives0.20.20.80.3-0.10.10.4-0.40.4-0.7-0.2-0.1-0.9-0.1
Conditioned reinforcement - inactives1.31.52.1-1.3-1.31.3-1.41.4-1.41.5-1.2-1.01.0-0.2
Conditioned locomotion0.10.10.30.0-0.60.1-0.50.5-0.5-0.2-0.20.1-0.2-0.2
Patch foraging indifference point 0 sec0.10.21.3-0.3-0.30.2-0.30.3-0.30.5-0.4-0.40.11.2
Patch foraging indifference point AUC0.10.10.40.00.00.20.3-0.30.3-0.3-0.3-0.4-0.20.6
Delay disc. indifference point, 0s delay0.20.21.40.20.0-0.4-0.00.0-0.0-0.30.50.2-0.0-1.2
Delay disc. indifference point, 16s delay2.42.44.41.81.5-1.11.8-1.81.8-2.11.10.8-2.0-0.2
Delay disc. indifference point, 2s delay0.20.20.60.50.3-0.7-0.40.4-0.4-0.30.80.7-0.1-0.4
Delay disc. indifference point, 24s delay3.12.96.82.12.2-2.60.6-0.60.6-1.12.62.4-1.0-0.8
Delay disc. indifference point, 4s delay0.20.20.50.50.6-0.60.0-0.00.0-0.30.70.7-0.2-0.4
Delay disc. indifference point, 8s delay0.60.62.00.60.9-1.1-0.20.2-0.2-0.21.10.8-0.1-1.4
Indifference point function ln k0.91.21.91.11.3-1.11.0-1.01.0-0.81.31.4-1.0-0.8
Indifference point function log k0.91.21.91.11.3-1.11.0-1.01.0-0.81.31.4-1.0-0.8
Patch foraging total patch changes 0 sec0.10.21.1-0.3-0.20.2-0.10.1-0.10.3-0.4-0.5-0.11.1
Patch foraging total patch changes 12 sec0.20.31.7-0.2-0.20.1-0.50.5-0.50.5-0.3-0.30.31.3
Patch foraging total patch changes 18 sec0.70.84.50.50.4-0.01.0-1.01.0-0.8-0.1-0.1-0.92.1
Patch foraging total patch changes 24 sec0.40.51.0-0.7-1.00.8-0.60.6-0.60.5-0.9-0.50.31.0
Patch foraging total patch changes 6 sec0.50.71.2-0.8-0.70.7-1.01.0-1.01.0-0.8-0.70.51.1
Patch foraging time to switch 0 sec0.20.40.80.90.8-0.90.3-0.30.3-0.40.80.7-0.3-0.6
Patch foraging water rate 0 sec1.21.94.6-1.8-1.82.1-0.60.6-0.60.7-2.1-1.80.40.9
Patch foraging water rate 12 sec0.30.40.8-0.4-0.30.90.9-0.90.9-0.7-0.4-0.7-0.30.5
Patch foraging water rate 18 sec0.30.51.4-0.5-0.71.20.5-0.50.5-0.5-0.9-0.9-0.60.3
Patch foraging water rate 24 sec1.11.54.4-1.2-1.62.10.4-0.40.4-0.3-1.7-1.7-0.11.3
Patch foraging water rate 6 sec0.10.20.4-0.3-0.20.60.5-0.50.5-0.60.0-0.4-0.6-0.5
Seeking ratio, delayed vs. immediate footshock1.11.32.5-1.4-1.61.6-0.90.9-0.90.8-1.5-1.30.4-0.7
Distance traveled before self-admin1.71.83.7-1.5-1.20.6-1.61.6-1.61.9-0.7-0.41.5-1.1
Distance traveled after self-admin0.60.62.6-0.4-0.50.90.3-0.30.30.4-1.3-0.9-0.41.6
Extensor digitorum longus weight0.20.91.70.2-0.20.61.3-1.31.3-1.3-0.7-0.9-1.10.7
Bone: elastic displacement1.41.62.3-1.5-1.51.1-1.51.5-1.51.5-0.9-0.81.3-0.3
Bone: elastic work7.910.215.3-3.9-3.42.7-3.83.8-3.83.9-2.1-1.93.5-0.6
Bone: endosteal estimation0.30.61.90.40.10.20.9-0.90.9-0.9-0.5-0.5-0.91.4
Bone: endosteal perimeter0.51.01.7-1.1-1.31.0-0.90.9-0.90.9-1.3-1.00.60.3
Epididymis fat weight0.51.12.6-1.3-1.61.6-0.60.6-0.60.4-1.6-1.30.40.2
Delta time in closed arm before/after self-admin0.30.31.20.40.2-0.10.2-0.20.2-0.80.0-0.2-0.8-1.1
Delta time in open arm before/after self-admin0.20.21.50.1-0.3-0.10.3-0.30.3-0.20.0-0.1-0.31.2
Diff in mean of infusions in LGA sessions0.30.31.60.60.5-0.8-0.10.1-0.10.10.61.30.10.6
Delay discount exponential model param1.31.42.8-1.5-1.61.6-0.60.6-0.61.0-1.7-1.40.80.6
Extinction: sum of active levers before priming1.31.33.81.01.0-1.80.6-0.60.6-0.41.91.90.0-0.1
Active lever presses in extinction session 60.80.81.60.10.2-1.1-1.01.0-1.00.81.31.30.4-0.2
Bone: final force4.16.613.3-3.7-3.33.1-2.52.5-2.52.5-2.2-2.22.20.1
Bone: final moment5.08.215.5-3.9-3.63.2-2.92.9-2.92.9-2.4-2.42.50.2
Food consumed during 24 hour testing period0.30.40.8-0.5-0.80.7-0.50.5-0.50.4-0.9-0.80.2-0.7
Glucose2.23.48.40.91.8-2.4-0.90.9-0.90.92.92.91.2-2.4
Heart weight0.40.61.2-1.1-1.10.8-0.50.5-0.50.6-0.4-0.61.10.9
Delay discount hyperbolic model param1.31.32.7-1.5-1.61.6-0.50.5-0.51.0-1.6-1.40.80.7
Intermittent access intake day 1-15 change0.90.91.6-1.0-0.81.0-0.80.8-0.81.0-1.3-1.01.00.4
Intermittent access intake escalation0.70.71.7-0.8-0.81.0-0.70.7-0.70.7-1.3-1.10.60.5
Intermittent access intake escalation 23.13.14.8-1.7-1.71.1-2.22.2-2.21.6-1.3-1.02.11.5
Intermitt. access day 1 inactive lever presses1.21.32.1-1.3-0.91.1-1.41.4-1.41.4-1.0-0.81.2-0.4
Intermitt. access day 15 inactive lever presses0.60.61.5-0.8-1.21.2-0.40.4-0.40.2-1.2-1.00.2-0.6
Intermitt. access escalation Index0.70.72.1-0.3-0.81.10.4-0.40.4-0.4-1.3-1.4-0.9-0.3
Intermittent access day 1 total infusions0.30.30.8-0.7-0.40.8-0.10.1-0.10.5-0.7-0.90.20.5
Intermittent access day 15 total infusions0.60.71.6-0.8-0.91.1-0.40.4-0.40.6-1.3-1.20.40.7
Intermittent access terminal intake (last 3 days)1.11.22.2-1.1-1.21.3-0.90.9-0.91.0-1.5-1.31.00.9
Intermittent access total infusions0.40.51.2-0.8-0.71.0-0.30.3-0.30.6-1.1-1.10.30.4
Intermittent access day 1 locomotion0.30.31.2-0.4-0.50.7-0.30.3-0.3-0.0-0.6-0.9-0.1-1.1
Intermittent access day 15 total locomotion0.70.71.0-0.8-0.60.7-1.01.0-1.00.7-0.8-0.90.90.9
Intermittent access total locomotion0.50.50.9-0.7-0.70.8-0.80.8-0.80.5-0.7-1.00.5-0.6
Intermittent access standard deviation1.01.11.6-0.10.3-1.0-1.31.3-1.31.10.91.31.1-1.0
Left kidney weight0.20.71.3-0.7-0.60.0-1.21.2-1.20.90.40.10.70.9
Right kidney weight0.00.10.5-0.2-0.1-0.2-0.30.3-0.30.10.7-0.00.10.4
Cocaine induced anxiety5.56.311.7-3.0-2.51.5-3.03.0-3.03.4-1.4-0.93.10.4
Post-drug Anxiety1.11.22.9-1.2-0.70.4-1.31.3-1.31.7-0.2-0.11.5-0.7
Baseline Anxiety6.77.210.23.23.2-2.52.7-2.72.7-3.02.61.9-2.6-2.2
Tail length3.711.126.4-3.7-4.15.0-1.61.6-1.61.7-5.1-4.91.51.9
Length with tail2.07.310.7-3.3-3.33.0-2.92.9-2.92.6-2.8-2.61.90.3
Length without tail1.02.33.9-0.30.1-1.4-2.02.0-2.01.51.91.51.1-1.4
Times rat made contact with spout2.12.43.9-1.3-1.30.9-2.02.0-2.01.9-1.2-1.21.90.7
Lifetime Intake0.10.10.4-0.3-0.30.5-0.10.1-0.10.4-0.6-0.60.00.5
Liver weight, left0.30.61.1-0.20.1-0.7-0.80.8-0.80.90.80.91.1-0.4
Liver weight, right1.42.34.2-1.8-2.01.6-1.71.7-1.71.3-1.5-1.41.2-0.2
Locomotor activity0.60.92.91.00.9-1.20.3-0.30.3-0.61.21.7-0.71.1
Locomotor testing distance0.91.53.81.51.0-1.30.7-0.70.7-1.21.32.0-1.50.6
Locomotor testing rearing0.40.61.31.10.4-0.70.6-0.60.6-1.00.40.8-0.91.1
Locomotion in novel chamber0.40.51.00.70.4-0.60.9-0.90.9-1.00.50.3-0.5-0.4
Locomotion in novel chamber post-restriction2.02.44.5-1.8-1.62.1-1.01.0-1.01.4-2.1-2.01.20.7
Fecal boli incidents, locomotor time 10.50.51.01.00.5-0.80.6-0.60.6-0.90.70.5-1.00.1
Change in fecal boli incidents, locomotor task1.31.23.30.81.4-1.5-0.10.1-0.10.51.41.70.41.8
Time >=10cm from walls, locomotor time 11.01.02.7-0.3-0.61.11.1-1.11.1-0.7-1.3-1.6-0.40.8
Bouts of movement, locomotor time 11.31.53.61.31.4-1.30.9-0.90.9-0.81.61.9-0.9-0.6
Total resting periods, locomotor time 11.41.54.11.41.5-1.50.7-0.70.7-0.61.72.0-0.8-0.6
Rest time, locomotor task time 10.30.30.80.20.3-0.5-0.70.7-0.70.40.60.90.10.0
Distance moved, locomotor task time 10.40.41.7-0.6-0.50.90.3-0.30.30.0-0.9-0.80.1-1.3
Vertical activity count, locomotor time 10.70.71.9-0.6-1.11.10.4-0.40.4-0.4-1.2-1.00.2-1.4
Time >=10cm from walls, locomotor time 20.10.10.4-0.2-0.20.20.2-0.20.2-0.3-0.1-0.70.2-0.4
Bouts of movement, locomotor time 21.51.75.11.21.4-1.01.2-1.21.2-1.21.11.0-1.0-2.3
Total resting periods, locomotor time 21.41.53.91.11.2-0.71.3-1.31.3-1.30.70.7-1.3-2.0
Rest time, locomotor task time 20.10.20.70.40.5-0.10.0-0.00.0-0.2-0.00.6-0.60.8
Distance moved, locomotor task time 20.20.32.6-0.2-0.10.10.1-0.10.1-0.10.1-0.20.3-1.6
Vertical activity count, locomotor time 20.50.52.5-0.0-0.30.20.8-0.80.8-0.9-0.1-0.5-0.0-1.6
Light reinforcement 10.50.92.9-0.8-1.41.50.4-0.40.4-0.4-1.7-1.40.0-0.1
Light reinforcement 21.01.43.6-1.4-1.91.7-0.60.6-0.60.4-1.8-1.30.60.4
Bone: marrow area0.30.61.80.40.10.20.9-0.90.9-0.9-0.5-0.5-0.91.3
Bone: maximum diameter1.01.73.4-1.8-1.81.5-1.31.3-1.31.3-1.3-1.00.90.4
Bone: maximum force4.06.914.0-3.7-3.43.3-2.32.3-2.32.3-2.4-2.52.20.1
Bone: maximum moment4.88.316.1-4.0-3.73.5-2.72.7-2.72.7-2.6-2.62.50.2
Mean time between licks in bursts1.31.82.71.61.6-1.51.3-1.31.3-1.31.41.4-1.30.3
Mean num. licks in bursts0.80.91.9-0.7-0.60.2-1.41.4-1.41.3-0.4-0.31.40.1
Cd content in liver1.51.62.21.41.5-1.31.3-1.31.3-1.31.51.2-1.1-0.7
Co content in liver0.20.20.70.60.4-0.50.2-0.20.2-0.20.30.4-0.80.8
Cu content in liver1.11.32.8-0.8-0.60.2-1.71.7-1.71.7-0.10.01.2-0.3
Fe content in liver0.81.01.81.31.1-1.20.9-0.90.9-0.90.91.1-0.80.2
K content in liver1.21.23.5-1.0-1.31.5-0.30.3-0.30.3-1.9-1.8-0.31.0
Mg content in liver0.90.92.10.3-0.10.71.1-1.11.1-1.1-1.0-1.1-1.50.8
Mn content in liver0.20.20.4-0.7-0.50.6-0.50.5-0.50.5-0.4-0.40.3-0.1
Na content in liver0.00.00.10.10.1-0.1-0.10.1-0.10.1-0.00.1-0.1-0.3
Rb content in liver0.60.72.2-0.9-1.11.40.1-0.10.1-0.1-1.3-1.50.00.6
Se content in liver0.20.30.9-0.4-0.60.7-0.20.2-0.20.2-1.0-1.00.00.1
Sr content in liver1.11.01.8-0.20.1-0.7-1.21.2-1.21.20.70.71.4-1.3
Zn content in liver0.10.10.80.20.2-0.1-0.20.2-0.20.20.00.0-0.3-0.9
Bone: minimum diameter2.64.87.8-2.7-2.82.1-2.42.4-2.42.3-2.1-1.91.70.1
Time in familiar zone, hab. session 10.20.21.2-0.2-0.0-0.0-0.30.3-0.30.40.3-0.20.7-1.1
Time in novel zone, hab. session 10.20.21.10.10.00.10.3-0.30.3-0.4-0.20.1-0.41.1
Total zone transitions, hab. session 10.40.50.80.70.7-0.50.9-0.90.9-0.80.70.5-0.7-0.6
Total locomotion distance, hab. session 10.10.10.2-0.0-0.30.20.5-0.50.5-0.4-0.3-0.5-0.4-0.4
Locomotion velocity, hab. session 10.10.10.2-0.0-0.30.20.5-0.50.5-0.3-0.3-0.4-0.5-0.3
Time in familiar zone, hab. session 20.20.20.40.60.5-0.40.6-0.60.6-0.50.30.3-0.3-0.5
Time in novel zone, hab. session 20.10.10.20.10.2-0.10.2-0.20.2-0.30.30.2-0.30.4
Total zone transitions, hab. session 21.21.53.30.80.70.11.8-1.81.8-1.80.0-0.3-1.70.1
Total locomotion distance, hab. session 20.81.01.7-0.0-0.50.91.2-1.21.2-1.3-1.0-1.1-1.20.6
Locomotion velocity, hab. session 20.71.01.9-0.3-0.71.21.0-1.01.0-0.9-1.2-1.4-1.00.5
Novel to familiar place preference ratio3.33.44.8-2.2-1.91.6-2.22.2-2.22.2-1.2-1.12.1-0.2
Novelty place preference3.23.34.8-2.1-1.91.5-2.22.2-2.22.2-1.2-1.02.1-0.3
Time in novel zone, NPP test2.52.63.7-1.9-1.71.4-1.91.9-1.91.9-1.1-0.91.9-0.3
Total zone transitions, NPP test1.92.75.91.31.0-0.22.3-2.32.3-2.30.1-0.1-2.40.2
Total locomotion distance, NPP test1.31.83.80.60.10.51.8-1.81.8-1.9-0.7-0.9-1.90.3
Locomotion velocity, NPP test0.81.12.20.3-0.20.71.4-1.41.4-1.4-0.8-1.0-1.50.2
Intraocular pressure0.50.71.8-0.8-1.01.3-0.40.4-0.40.1-1.3-1.20.20.2
Delta distance traveled before/after self-admin1.61.76.01.10.7-0.21.6-1.61.6-1.2-0.10.1-1.62.5
Delta ambulatory time before/after self-admin2.32.54.91.71.2-0.71.9-1.91.9-1.60.40.6-2.02.2
Parametrial fat weight1.42.75.0-1.8-2.11.9-1.41.4-1.41.5-2.0-2.21.2-0.5
Pavlov. Cond. lever latency1.51.93.71.31.1-0.51.9-1.91.9-1.70.60.6-1.6-0.3
Pavlov. Cond. magazine entry latency3.03.96.3-2.1-1.91.5-2.52.5-2.52.3-1.3-1.32.2-0.6
Pavlov. Cond. change in total contacts1.11.22.8-0.8-0.5-0.0-1.71.7-1.71.40.0-0.01.2-0.3
Pavlov. Cond. index score3.24.05.7-2.2-2.21.7-2.42.4-2.42.2-1.7-1.62.10.2
Pavlov. Cond. latency score2.83.55.5-2.0-1.91.4-2.32.3-2.32.2-1.4-1.32.10.3
Pavlov. Cond. lever contacts0.81.01.7-1.0-0.90.5-1.31.3-1.31.2-0.7-0.61.00.2
Pavlov. Cond. magazine entry number3.44.27.52.11.8-1.22.7-2.72.7-2.51.00.9-2.60.5
Pavlov. Cond. intertrial magazine entries0.30.41.2-0.2-0.50.80.5-0.50.5-0.5-0.9-1.1-0.4-0.2
Pavlov. Cond. lever-magazine prob. diff.3.44.26.0-2.3-2.21.7-2.42.4-2.42.3-1.7-1.62.1-0.1
Pavlov. Cond. response bias2.83.46.0-1.9-1.71.2-2.42.4-2.42.3-1.0-1.02.1-0.5
Pavlov. Cond. lever latency0.30.41.30.50.8-1.0-0.30.3-0.30.41.20.80.4-0.6
Pavlov. Cond. magazine entry latency2.32.64.51.81.6-1.11.9-1.91.9-1.90.91.6-2.10.0
Pavlov. Cond. change in total contacts0.40.61.20.70.4-0.21.1-1.11.1-1.10.10.2-1.10.1
Pavlov. Cond. index score0.40.51.50.70.4-0.10.9-0.90.9-1.0-0.10.4-1.2-0.1
Pavlov. Cond. latency score0.50.61.60.60.3-0.01.0-1.01.0-1.1-0.20.3-1.30.1
Pavlov. Cond. lever contacts0.50.72.1-0.6-1.01.30.4-0.40.4-0.5-1.5-1.1-0.40.9
Pavlov. Cond. magazine entry number1.72.14.2-1.6-1.31.0-1.71.7-1.71.8-0.7-1.22.00.4
Pavlov. Cond. intertrial magazine entries1.31.73.8-1.6-1.61.9-0.80.8-0.80.8-1.6-2.01.00.6
Pavlov. Cond. lever-magazine prob. diff.0.50.71.60.80.5-0.31.0-1.01.0-1.10.10.5-1.3-0.1
Pavlov. Cond. response bias0.30.40.90.1-0.10.50.8-0.80.8-0.9-0.6-0.0-0.90.5
Time in closed arm before self-admin0.20.31.0-0.20.4-0.3-0.40.4-0.41.00.50.60.90.0
Time in closed arm after self-admin0.70.81.70.20.8-0.9-0.60.6-0.60.91.01.10.9-1.3
Time in open arm before self-admin0.30.31.50.70.1-0.20.2-0.20.2-1.20.20.1-0.90.3
Time in open arm after self-admin0.50.61.50.60.2-0.30.7-0.70.7-1.10.30.0-1.21.2
Bone: periosteal estimation1.22.54.8-2.2-2.22.0-1.31.3-1.31.3-1.7-1.61.00.7
Bone: periosteal perimeter3.25.38.0-2.8-2.61.9-2.72.7-2.72.7-1.6-1.32.4-0.3
Bone: post-yield work0.20.30.70.20.20.10.8-0.80.8-0.9-0.1-0.2-0.6-0.2
Progressive ratio test 1 active lever presses0.80.82.0-1.0-1.01.3-0.40.4-0.40.7-1.4-1.20.40.9
Progressive ratio test 1 breakpoint1.01.02.6-1.2-1.21.4-0.40.4-0.40.9-1.6-1.40.60.6
Progressive ratio test 1 inactive lever presses1.41.63.3-1.6-1.71.8-0.70.7-0.70.8-1.8-1.60.70.5
Progressive ratio test 2 active lever presses0.60.60.8-0.7-0.70.8-0.80.8-0.80.7-0.9-0.80.40.9
Progressive ratio test 2 breakpoint0.50.51.2-0.6-0.81.0-0.60.6-0.60.4-1.1-1.00.20.6
Progressive ratio test 2 inactive lever presses0.60.71.1-0.8-0.80.7-1.11.1-1.10.9-0.6-0.60.70.5
Incentive Sensitization - Responses0.30.30.6-0.5-0.50.7-0.40.4-0.40.6-0.8-0.80.30.7
Incentive Sensitization - Breakpoint0.30.30.6-0.5-0.50.6-0.50.5-0.50.6-0.7-0.70.30.8
Sum of active levers in priming session hrs 5-61.41.32.2-1.2-1.00.5-1.31.3-1.31.5-0.5-0.51.31.4
Progressive ratio0.30.41.00.70.7-0.70.2-0.20.2-0.40.90.6-0.3-1.0
Food seeking constrained by brief footshock0.30.30.80.20.3-0.6-0.70.7-0.70.40.50.50.9-0.5
Seeking ratio, punishment vs. effort0.10.10.4-0.4-0.40.4-0.10.1-0.10.1-0.6-0.50.30.5
Retroperitoneal fat weight2.99.617.3-3.7-4.13.9-2.32.3-2.32.5-4.2-3.72.30.6
Reaction time number correct2.63.87.20.80.10.72.7-2.72.7-2.6-0.8-1.0-2.51.9
Reaction time mean minus median0.30.41.10.10.0-0.7-0.70.7-0.70.50.51.00.70.7
Reaction time mean minus median AUC0.10.10.4-0.0-0.3-0.2-0.40.4-0.40.10.10.60.30.6
Reaction time num false alarms0.10.20.30.60.5-0.50.4-0.40.4-0.20.50.4-0.2-0.6
Reaction time num false alarms AUC0.50.71.11.10.9-0.80.8-0.80.8-0.70.80.8-0.7-0.6
Reaction time trials correct on left2.63.87.20.80.10.72.7-2.72.7-2.6-0.8-1.0-2.51.9
Reaction time trials on left2.73.97.40.80.10.72.7-2.72.7-2.7-0.8-1.0-2.62.0
Reaction time mean0.20.31.0-0.5-0.80.4-0.20.2-0.20.1-0.6-0.50.71.0
Reaction time mean AUC0.20.31.7-0.2-0.70.40.1-0.10.1-0.3-0.6-0.50.31.3
Median of all reaction times0.20.30.8-0.5-0.70.60.0-0.00.0-0.1-0.6-0.80.40.9
Reaction time omissions0.20.32.70.1-0.50.00.0-0.00.0-0.3-0.40.1-0.21.6
Reaction time false alarm rate0.60.82.00.50.8-1.1-0.60.6-0.60.71.11.10.7-1.4
Reaction time premature initiation rate0.60.92.01.31.4-1.20.5-0.50.5-0.81.21.0-0.8-0.2
Reaction time premature initiations1.52.24.31.51.3-0.61.8-1.81.8-2.10.60.3-2.00.7
Std. dev. reaction times0.30.41.00.70.5-0.80.5-0.50.5-0.60.60.9-0.11.0
Reaction time trials completed2.73.97.40.80.10.72.7-2.72.7-2.7-0.8-1.0-2.62.0
Reaction time trials AUC2.63.87.20.7-0.00.72.7-2.72.7-2.6-0.9-1.2-2.52.0
Run reversals in cocaine runway, females1.31.22.20.90.7-0.71.5-1.51.5-1.30.40.4-1.01.5
Run reversals in cocaine runway, males2.52.54.9-1.4-1.40.8-2.22.2-2.21.8-0.9-0.51.60.8
Latency to leave start box in cocaine runway0.40.41.30.70.7-0.20.8-0.80.8-0.70.20.2-1.1-0.0
Latency to leave start box in cocaine runway, F0.80.92.11.00.6-0.11.0-1.01.0-1.40.20.2-1.41.1
Latency to leave start box in cocaine runway, M0.30.32.2-0.40.10.30.1-0.10.10.6-0.4-0.4-0.0-1.5
Std. dev. time between licks in bursts1.21.42.30.0-0.51.11.5-1.51.5-1.5-1.2-1.3-1.50.5
Total sessions with >9 infusions0.30.30.50.60.7-0.40.7-0.70.7-0.40.40.3-0.6-0.4
Short access day 1 total inactive lever presses0.30.31.20.5-0.00.30.4-0.40.4-1.1-0.1-0.1-1.10.3
Short access day 10 total inactive lever presses2.93.35.2-2.3-1.92.2-1.61.6-1.61.6-1.9-2.01.7-0.8
Short access day 1 total infusions1.31.42.41.41.4-1.50.9-0.90.9-0.91.51.6-0.90.0
Short access day 10 total infusions0.60.71.2-0.9-0.80.7-0.70.7-0.71.1-0.9-0.80.61.0
Short access total infusions0.00.00.10.00.20.00.3-0.30.30.2-0.10.00.00.2
Short access day 1 locomotion0.30.31.00.50.6-0.90.0-0.00.00.01.00.80.40.6
Short access day 10 total locomotion0.40.50.9-0.10.3-0.5-1.01.0-1.00.60.60.40.9-0.8
Short access total locomotion0.30.30.80.40.8-0.7-0.20.2-0.20.20.90.60.4-0.9
One hour access (0.3 mA shock)1.01.22.8-1.2-1.31.6-0.40.4-0.40.8-1.7-1.70.30.3
Compulsive drug intake0.30.31.3-0.6-0.70.7-0.20.2-0.20.5-0.6-0.50.1-1.1
One hour access (shock baseline)0.20.20.8-0.2-0.30.70.1-0.10.1-0.3-0.8-0.9-0.60.1
Social response proportion0.40.50.90.70.6-0.60.7-0.70.7-1.00.70.4-0.8-0.4
Social responses0.40.51.70.50.4-0.40.6-0.60.6-0.60.50.7-1.0-1.3
Social time0.20.30.80.40.3-0.30.7-0.70.7-0.60.50.5-0.5-0.9
Soleus weight0.82.55.0-1.9-2.12.2-1.01.0-1.01.0-2.2-2.00.90.4
Bone: stiffness0.40.62.0-1.4-1.11.2-0.60.6-0.60.5-0.5-0.60.50.2
Tibialis anterior weight0.10.30.50.1-0.10.40.7-0.70.7-0.7-0.6-0.6-0.50.7
Time to tail flick, vehicle, before self-admin0.50.55.1-0.1-0.50.30.2-0.20.2-0.1-0.4-0.50.02.3
Time to tail flick, vehicle, after self-admin1.92.13.41.71.6-1.51.2-1.21.2-1.11.71.8-1.3-1.2
Time to tail flick, test, before self-admin0.20.20.4-0.40.00.5-0.60.6-0.60.6-0.5-0.40.40.3
Time to tail flick, test, after self-admin0.20.30.60.60.4-0.7-0.00.0-0.00.10.80.7-0.60.4
Delta time to tail flick, vehicle, before/after SA0.90.93.00.90.7-0.40.8-0.80.8-0.90.50.7-1.1-1.7
Delta time to tail flick, test, before/after SA0.50.41.70.50.5-1.10.0-0.00.00.01.31.1-0.10.3
Tibia length8.022.638.4-6.2-5.65.0-5.15.1-5.15.0-3.8-3.74.7-0.2
Ambulatory time before self-admin2.42.53.9-2.0-1.71.1-1.81.8-1.82.0-1.2-0.91.7-0.5
Ambulatory time after self-admin0.30.31.7-0.4-0.50.50.0-0.00.00.5-0.9-0.5-0.31.3
Bone: tissue strength0.60.61.6-1.0-1.11.3-0.20.2-0.20.2-1.1-1.0-0.00.4
Total heroin consumption1.01.22.3-0.6-0.4-0.6-1.51.5-1.51.30.81.11.3-0.6
Bone: trabecular number0.00.00.10.0-0.10.10.1-0.10.1-0.1-0.2-0.2-0.10.3
Bone: trabecular spacing0.91.12.40.3-0.20.71.4-1.41.4-1.4-0.8-0.8-1.50.3
Bone: trabecular thickness1.51.83.5-1.2-0.80.3-1.91.9-1.91.9-0.1-0.11.8-0.3
Bone: trabecular tissue density0.60.91.51.11.2-1.10.8-0.80.8-0.81.21.0-0.8-0.3
Water consumed over 24 hours0.20.30.60.00.0-0.4-0.70.7-0.70.70.30.40.50.1
Number of responses in last shaping day0.60.61.5-0.8-1.00.8-0.60.6-0.60.3-0.6-1.1-0.0-1.2