Hub : Genes

Gpr132

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 BLA alternative TSS XM_017594192.2 0.06 0.05 5.0e-03 0.01 0.03 -0 0.01 8.1e-02 1.3e-02 4.7e-01 7.5e-02
2 PL gene expression Gpr132 0.04 0.04 1.5e-04 0.03 0.04 0.02 0.03 2.2e-04 4.7e-05 1.0e-03 2.6e-04
3 Brain alternative TSS XM_017594192.2 0.03 0.02 2.8e-03 0.02 0.03 0.01 0.02 2.8e-03 1.3e-03 3.2e-02 2.8e-03
4 BLA gene expression Gpr132 0.08 0.07 1.3e-03 0.05 0.06 0.04 0.05 1.0e-03 6.9e-04 2.4e-03 1.3e-03
5 Brain alternative TSS XM_039112427.1 0.03 0.03 8.4e-04 0.04 0.03 0.03 0.04 6.4e-05 4.4e-04 3.4e-04 1.3e-04
6 Brain gene expression Gpr132 0.02 0.02 5.4e-03 0.01 0.02 0.01 0.01 2.0e-02 6.8e-03 5.4e-02 3.0e-02
7 Adipose alternative TSS XM_017594192.2 0.07 0.05 5.4e-07 0.04 0.04 0.05 0.05 1.4e-05 8.1e-06 4.2e-06 5.5e-06
8 Adipose mRNA stability Gpr132 0.03 0.02 2.6e-03 0.01 0.01 0.01 0.01 8.8e-03 1.7e-02 5.3e-02 1.7e-02
9 PL alternative TSS XM_039112427.1 0.05 0.04 6.2e-06 0.04 0.05 0.05 0.05 2.4e-05 2.6e-06 2.8e-06 8.2e-06
10 PL alternative TSS XM_017594192.2 0.02 0.02 4.8e-03 0.03 0.02 0.03 0.02 5.3e-04 6.4e-03 6.6e-04 2.2e-03
11 PL alternative TSS XM_017594192.2 0.05 0.03 4.3e-07 0.07 0.06 0.07 0.07 2.7e-08 1.2e-07 3.1e-08 9.2e-08
12 PL alternative TSS XM_039112427.1 0.05 0.03 8.5e-07 0.08 0.06 0.07 0.07 5.2e-09 6.1e-07 1.3e-08 3.5e-08

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12
Bone: apparent density0.00.00.1-0.20.2-0.20.2-0.40.10.2-0.10.10.20.2-0.2
Area under the delay curve1.01.11.81.3-1.31.2-1.11.2-1.0-1.11.3-0.8-0.6-0.60.6
BMI with tail1.85.86.72.3-2.12.4-2.52.5-2.5-2.22.0-2.6-2.6-2.62.6
BMI without tail0.71.52.31.3-1.31.3-1.31.5-1.2-0.81.1-1.1-1.1-1.11.1
Body weight1.56.28.2-2.72.8-2.62.5-2.42.52.4-2.92.32.32.3-2.3
Weight adjusted by age0.20.20.4-0.40.3-0.40.5-0.30.50.0-0.30.50.60.6-0.6
Bone surface0.20.40.80.7-0.80.6-0.60.7-0.6-0.40.9-0.5-0.6-0.60.6
Bone volume0.20.30.60.6-0.70.5-0.50.5-0.4-0.30.8-0.3-0.4-0.40.4
Breakpoint value in progressive ratio session0.00.00.1-0.10.2-0.0-0.0-0.0-0.1-0.10.2-0.3-0.3-0.30.3
Number of licking bursts0.91.11.81.2-1.31.1-1.01.1-1.0-0.91.4-0.8-0.8-0.80.8
Context. condit. distance diff. score3.54.24.7-2.02.0-2.12.1-2.12.12.0-2.02.21.91.9-1.9
Locomotion velocity, session 10.20.20.4-0.40.4-0.40.5-0.60.40.3-0.30.40.60.6-0.6
Locomotion distance, session 10.20.20.50.4-0.40.5-0.50.2-0.6-0.60.5-0.7-0.5-0.50.5
Locomotion velocity, session 20.20.30.80.6-0.70.5-0.50.6-0.5-0.40.9-0.4-0.3-0.30.3
Locomotion distance, session 20.60.91.31.0-1.00.9-0.91.2-0.9-0.81.1-0.8-0.8-0.80.8
Locomotion velocity, session 30.10.10.50.1-0.20.1-0.0-0.1-0.20.10.7-0.3-0.1-0.10.1
Locomotion distance, session 30.10.10.40.2-0.30.2-0.10.1-0.2-0.00.6-0.2-0.1-0.10.1
Stereotopy head waving bouts, day 30.00.10.1-0.20.2-0.20.3-0.10.20.3-0.10.20.20.2-0.2
Stereotopy head waving duration, day 30.10.10.2-0.20.2-0.30.3-0.20.30.4-0.10.30.30.3-0.3
Locomotion velocity, session 70.00.00.1-0.30.4-0.20.1-0.30.0-0.1-0.4-0.20.10.1-0.1
Locomotion distance, session 70.81.01.11.0-1.01.0-1.00.9-1.1-1.01.0-1.0-0.9-0.90.9
Stereotopy head waving bouts, day 72.73.03.2-1.81.8-1.81.8-1.81.71.7-1.61.61.81.8-1.8
Stereotopy head waving duration, day 71.61.92.3-1.51.5-1.41.4-1.51.41.3-1.31.21.31.3-1.3
Locomotion velocity, session 82.12.53.2-1.71.8-1.71.7-1.51.61.6-1.71.51.41.4-1.4
Locomotion distance, session 80.40.60.7-0.80.8-0.80.8-0.80.80.8-0.60.70.70.7-0.7
Degree of sensitization distance0.20.20.40.5-0.40.5-0.50.5-0.5-0.60.1-0.5-0.5-0.50.5
Degree of sensitization stereotypy1.01.11.3-1.11.2-1.11.1-1.21.01.0-1.10.91.01.0-1.0
Conditioned locomotion1.72.02.2-1.51.5-1.51.5-1.41.51.4-1.51.41.41.4-1.4
Cocaine response after cond. corrected0.10.10.3-0.10.20.1-0.1-0.1-0.2-0.1-0.1-0.5-0.4-0.40.4
Cocaine response after cond. not corrected0.60.61.20.5-0.30.6-0.70.5-0.8-0.70.4-1.1-1.1-1.11.1
Cocaine response before conditioning2.63.13.71.8-1.71.8-1.81.8-1.7-1.81.4-1.6-1.9-1.91.9
Saline control response0.10.10.2-0.20.1-0.20.3-0.40.20.40.20.10.20.2-0.2
Bone: connectivity density0.30.50.7-0.80.8-0.80.8-0.90.80.8-0.70.70.50.5-0.5
Bone: cortical apparent density4.76.27.5-2.32.2-2.42.5-2.52.62.5-2.32.72.62.6-2.6
Bone: cortical area0.20.20.3-0.40.3-0.50.5-0.60.50.6-0.10.50.50.5-0.5
Bone: cortical porosity0.20.20.4-0.40.4-0.50.5-0.20.50.5-0.40.60.30.3-0.3
Bone: cortical porosity0.10.20.3-0.50.5-0.40.4-0.30.40.4-0.50.40.20.2-0.2
Bone: cortical thickness0.61.01.5-1.11.1-1.01.0-1.20.91.0-0.90.80.90.9-0.9
Bone: cortical thickness0.70.81.1-0.80.6-0.80.9-1.00.91.1-0.50.91.01.0-1.0
Bone: cortical tissue density4.66.17.6-2.32.1-2.42.5-2.42.62.4-2.32.82.62.6-2.6
Condit. Reinf. active minus inactive responses0.20.30.50.5-0.50.5-0.50.2-0.6-0.70.5-0.7-0.5-0.50.5
Condit. Reinf. active-inactive response ratio1.81.92.91.3-1.21.4-1.41.1-1.5-1.71.1-1.6-1.4-1.41.4
Condit. Reinf. active responses0.10.10.2-0.30.3-0.20.2-0.50.10.0-0.3-0.10.20.2-0.2
Condit. Reinf. inactive responses2.32.83.3-1.71.6-1.71.7-1.71.61.8-1.31.51.71.7-1.7
Incentive salience index mean0.00.00.1-0.10.2-0.0-0.0-0.3-0.1-0.2-0.2-0.4-0.1-0.10.1
Condit. Reinf. lever presses0.20.20.6-0.60.7-0.50.4-0.60.30.2-0.80.10.20.2-0.2
Condit. Reinf. active minus inactive responses0.40.50.9-0.60.5-0.70.8-0.60.80.8-0.50.90.80.8-0.8
Condit. Reinf. active-inactive response ratio0.20.20.5-0.30.2-0.40.4-0.10.50.5-0.20.70.40.4-0.4
Condit. Reinf. active responses0.00.00.10.0-0.1-0.00.1-0.00.10.10.00.30.20.2-0.2
Condit. Reinf. inactive responses0.20.30.40.6-0.60.6-0.60.3-0.6-0.60.4-0.6-0.4-0.40.4
Condit. Reinf. lever presses1.92.63.21.7-1.81.6-1.61.6-1.5-1.51.7-1.3-1.6-1.61.6
Condit. Reinf. lever reinforcers received0.00.00.10.0-0.1-0.10.1-0.10.20.10.00.30.30.3-0.3
Conditioned reinforcement - actives1.11.11.5-0.90.8-1.01.0-1.01.11.1-0.61.21.21.2-1.2
Conditioned reinforcement - inactives0.50.60.9-0.60.6-0.70.7-0.90.70.8-0.40.70.90.9-0.9
Conditioned locomotion0.00.00.10.1-0.00.1-0.1-0.0-0.2-0.30.1-0.3-0.2-0.20.2
Patch foraging indifference point 0 sec6.310.111.6-3.43.4-3.43.4-3.43.33.1-3.13.12.82.8-2.8
Patch foraging indifference point AUC6.17.19.9-3.03.1-2.82.8-2.92.62.6-3.02.22.12.1-2.1
Delay disc. indifference point, 0s delay0.40.40.6-0.60.6-0.60.6-0.60.60.5-0.60.70.80.8-0.8
Delay disc. indifference point, 16s delay1.31.32.01.4-1.41.2-1.21.1-1.1-1.31.2-0.9-0.9-0.90.9
Delay disc. indifference point, 2s delay3.33.66.32.2-2.32.0-2.02.1-1.9-2.02.5-1.5-1.2-1.21.2
Delay disc. indifference point, 24s delay1.11.01.51.2-1.21.1-1.11.0-1.0-1.21.2-0.9-0.7-0.70.7
Delay disc. indifference point, 4s delay0.30.30.90.7-0.90.6-0.50.8-0.4-0.30.9-0.10.10.1-0.1
Delay disc. indifference point, 8s delay0.30.40.60.7-0.70.7-0.70.7-0.6-0.50.7-0.4-0.4-0.40.4
Indifference point function ln k0.50.71.2-0.50.4-0.70.7-0.60.81.1-0.51.11.01.0-1.0
Indifference point function log k0.50.71.2-0.50.4-0.70.7-0.60.81.1-0.51.11.01.0-1.0
Patch foraging total patch changes 0 sec7.612.214.0-3.73.7-3.73.7-3.73.63.4-3.53.43.13.1-3.1
Patch foraging total patch changes 12 sec3.95.05.9-2.32.2-2.42.4-2.42.32.1-2.02.22.12.1-2.1
Patch foraging total patch changes 18 sec2.63.34.3-2.02.0-1.92.0-2.11.81.7-1.71.61.61.6-1.6
Patch foraging total patch changes 24 sec1.21.52.1-1.41.4-1.31.3-1.31.21.0-1.31.01.01.0-1.0
Patch foraging total patch changes 6 sec5.98.711.9-3.43.5-3.23.2-3.33.02.8-3.12.52.42.4-2.4
Patch foraging time to switch 0 sec12.319.120.24.5-4.44.5-4.54.2-4.5-4.54.3-4.3-4.3-4.34.3
Patch foraging water rate 0 sec18.028.831.8-5.45.2-5.55.6-5.25.55.6-5.05.55.35.3-5.3
Patch foraging water rate 12 sec6.610.113.2-2.72.5-3.03.1-2.73.23.3-2.73.63.63.6-3.6
Patch foraging water rate 18 sec4.15.56.9-2.22.0-2.32.4-1.82.42.3-2.02.62.62.6-2.6
Patch foraging water rate 24 sec2.94.15.5-1.91.8-2.02.1-1.62.22.3-1.72.32.12.1-2.1
Patch foraging water rate 6 sec4.46.47.3-2.52.4-2.62.6-2.22.62.6-2.32.72.62.6-2.6
Seeking ratio, delayed vs. immediate footshock0.40.50.6-0.70.6-0.70.7-0.80.70.6-0.70.70.80.8-0.8
Distance traveled before self-admin0.90.91.51.0-1.01.0-1.01.0-1.0-1.20.9-0.9-0.9-0.90.9
Distance traveled after self-admin0.10.20.4-0.20.1-0.30.3-0.10.40.30.10.60.60.6-0.6
Extensor digitorum longus weight10.139.641.0-6.46.3-6.46.4-6.46.36.3-6.16.16.26.2-6.2
Bone: elastic displacement0.00.10.10.2-0.30.1-0.10.10.00.10.20.30.30.3-0.3
Bone: elastic work0.60.81.51.1-1.20.9-0.91.1-0.8-0.81.1-0.4-0.6-0.60.6
Bone: endosteal estimation1.22.54.11.9-2.01.6-1.51.8-1.4-1.32.0-1.1-1.3-1.31.3
Bone: endosteal perimeter0.20.41.00.7-0.80.6-0.50.8-0.6-0.41.0-0.5-0.6-0.60.6
Epididymis fat weight2.25.26.62.1-1.92.2-2.32.1-2.4-2.21.7-2.5-2.6-2.62.6
Delta time in closed arm before/after self-admin0.10.10.1-0.30.3-0.30.3-0.10.30.4-0.40.20.20.2-0.2
Delta time in open arm before/after self-admin1.00.91.1-1.01.1-1.01.0-1.00.91.0-0.80.81.01.0-1.0
Diff in mean of infusions in LGA sessions0.50.51.2-1.01.1-0.80.8-1.10.60.7-0.80.30.30.3-0.3
Delay discount exponential model param0.80.91.4-1.11.2-1.01.0-1.10.91.0-1.20.60.50.5-0.5
Extinction: sum of active levers before priming0.00.00.10.00.00.1-0.1-0.1-0.2-0.20.0-0.3-0.1-0.10.1
Active lever presses in extinction session 61.51.41.5-1.21.1-1.21.2-1.21.21.2-1.11.21.21.2-1.2
Bone: final force0.10.20.60.5-0.70.4-0.30.6-0.2-0.30.70.0-0.3-0.30.3
Bone: final moment0.00.10.30.3-0.40.2-0.10.4-0.0-0.10.50.2-0.1-0.10.1
Food consumed during 24 hour testing period1.01.21.5-1.11.1-1.11.1-1.01.11.1-0.91.01.21.2-1.2
Glucose0.00.10.20.0-0.1-0.10.2-0.10.20.20.20.40.40.4-0.4
Heart weight0.10.20.40.5-0.50.4-0.30.6-0.3-0.60.6-0.2-0.3-0.30.3
Delay discount hyperbolic model param1.11.12.0-1.31.4-1.21.2-1.21.11.1-1.40.80.50.5-0.5
Intermittent access intake day 1-15 change1.51.51.81.2-1.21.3-1.31.1-1.3-1.11.1-1.4-1.2-1.21.2
Intermittent access intake escalation1.41.41.81.2-1.21.2-1.21.1-1.3-0.81.1-1.3-1.2-1.21.2
Intermittent access intake escalation 20.20.20.30.4-0.30.4-0.40.3-0.5-0.30.3-0.6-0.5-0.50.5
Intermitt. access day 1 inactive lever presses3.33.54.0-1.81.7-1.81.9-2.01.91.8-1.91.91.91.9-1.9
Intermitt. access day 15 inactive lever presses0.60.71.0-0.60.5-0.70.8-0.80.80.9-0.50.91.01.0-1.0
Intermitt. access escalation Index0.10.10.1-0.1-0.0-0.10.2-0.40.20.30.30.30.30.3-0.3
Intermittent access day 1 total infusions0.00.00.1-0.30.3-0.20.2-0.20.10.2-0.3-0.0-0.0-0.00.0
Intermittent access day 15 total infusions0.91.01.51.0-0.91.0-1.01.0-1.1-0.60.9-1.2-1.1-1.11.1
Intermittent access terminal intake (last 3 days)1.31.41.91.2-1.11.2-1.21.2-1.3-1.01.2-1.4-1.2-1.21.2
Intermittent access total infusions0.10.10.20.2-0.20.3-0.30.3-0.4-0.10.2-0.5-0.4-0.40.4
Intermittent access day 1 locomotion0.10.10.20.1-0.00.1-0.20.2-0.2-0.30.1-0.3-0.4-0.40.4
Intermittent access day 15 total locomotion0.00.00.10.2-0.20.2-0.20.3-0.2-0.10.0-0.2-0.2-0.20.2
Intermittent access total locomotion0.00.00.1-0.20.3-0.10.1-0.10.10.1-0.1-0.1-0.1-0.10.1
Intermittent access standard deviation0.80.91.80.6-0.50.8-0.90.6-1.0-0.70.3-1.3-1.2-1.21.2
Left kidney weight2.87.99.0-3.03.0-3.02.9-2.73.02.8-2.92.92.52.5-2.5
Right kidney weight1.54.14.6-2.12.0-2.12.1-1.82.12.1-2.02.12.02.0-2.0
Cocaine induced anxiety0.50.50.9-0.60.5-0.70.8-0.60.80.6-0.31.00.90.9-0.9
Post-drug Anxiety0.40.40.6-0.60.6-0.70.7-0.40.70.6-0.20.80.70.7-0.7
Baseline Anxiety0.80.91.20.8-0.70.9-0.90.9-1.0-0.90.8-1.1-1.1-1.11.1
Tail length5.516.718.3-4.03.9-4.04.0-4.04.14.3-4.04.14.24.2-4.2
Length with tail9.735.436.9-6.16.1-6.06.0-6.06.05.7-6.05.85.95.9-5.9
Length without tail5.712.414.8-3.83.9-3.73.6-3.73.63.0-3.83.33.23.2-3.2
Times rat made contact with spout0.20.30.4-0.50.5-0.50.5-0.60.40.4-0.30.30.70.7-0.7
Lifetime Intake0.10.10.20.4-0.40.4-0.30.5-0.4-0.10.3-0.3-0.3-0.30.3
Liver weight, left2.64.24.9-2.12.1-2.12.1-1.92.12.2-2.22.11.91.9-1.9
Liver weight, right0.50.81.3-1.11.1-0.90.9-1.10.80.8-1.00.50.90.9-0.9
Locomotor activity0.10.20.3-0.40.4-0.40.4-0.30.4-0.0-0.50.50.50.5-0.5
Locomotor testing distance0.10.10.3-0.30.2-0.30.4-0.30.4-0.0-0.30.50.50.5-0.5
Locomotor testing rearing2.13.34.61.8-1.81.8-1.81.6-1.8-2.11.9-1.9-1.8-1.81.8
Locomotion in novel chamber3.64.56.3-1.81.7-2.02.1-1.82.22.2-1.72.52.42.4-2.4
Locomotion in novel chamber post-restriction0.20.20.60.5-0.50.4-0.40.8-0.4-0.40.5-0.2-0.3-0.30.3
Fecal boli incidents, locomotor time 10.50.61.10.4-0.20.6-0.70.8-0.8-0.80.2-1.1-1.0-1.01.0
Change in fecal boli incidents, locomotor task2.01.92.5-1.21.1-1.31.4-1.21.41.5-1.21.61.51.5-1.5
Time >=10cm from walls, locomotor time 12.02.04.5-1.82.0-1.61.5-1.61.31.2-2.10.80.60.6-0.6
Bouts of movement, locomotor time 11.31.41.81.1-1.11.2-1.21.0-1.3-1.11.3-1.4-1.2-1.21.2
Total resting periods, locomotor time 11.41.51.91.2-1.21.3-1.31.1-1.3-1.11.3-1.4-1.2-1.21.2
Rest time, locomotor task time 10.30.30.70.7-0.80.6-0.60.8-0.6-0.30.8-0.4-0.1-0.10.1
Distance moved, locomotor task time 10.90.91.31.0-1.01.0-1.00.9-0.9-1.20.7-0.8-1.0-1.01.0
Vertical activity count, locomotor time 10.10.10.10.3-0.30.2-0.20.3-0.1-0.40.10.1-0.3-0.30.3
Time >=10cm from walls, locomotor time 22.12.23.4-1.81.8-1.61.6-1.61.51.4-1.51.21.21.2-1.2
Bouts of movement, locomotor time 20.30.30.90.2-0.4-0.00.20.10.20.00.60.60.90.9-0.9
Total resting periods, locomotor time 20.20.20.60.4-0.60.1-0.00.20.1-0.10.60.50.70.7-0.7
Rest time, locomotor task time 20.00.00.10.3-0.40.2-0.20.1-0.1-0.10.10.10.20.2-0.2
Distance moved, locomotor task time 20.50.50.80.6-0.60.6-0.70.6-0.7-0.90.7-0.7-0.9-0.90.9
Vertical activity count, locomotor time 20.00.00.1-0.20.3-0.30.2-0.20.2-0.1-0.30.2-0.0-0.00.0
Light reinforcement 10.00.00.0-0.10.1-0.10.10.10.10.2-0.10.1-0.1-0.10.1
Light reinforcement 21.52.02.61.3-1.11.4-1.51.4-1.4-1.60.7-1.5-1.6-1.61.6
Bone: marrow area1.22.54.11.8-2.01.6-1.51.8-1.4-1.32.0-1.1-1.3-1.31.3
Bone: maximum diameter0.20.30.70.5-0.60.5-0.50.4-0.6-0.40.8-0.6-0.5-0.50.5
Bone: maximum force0.00.00.10.1-0.20.00.10.20.1-0.00.30.2-0.1-0.10.1
Bone: maximum moment0.00.00.1-0.10.0-0.20.20.00.20.20.10.30.10.1-0.1
Mean time between licks in bursts0.60.81.00.9-0.90.9-1.00.9-0.9-1.00.7-0.8-1.0-1.01.0
Mean num. licks in bursts1.31.62.3-1.41.5-1.31.3-1.41.21.1-1.41.01.11.1-1.1
Cd content in liver0.80.91.6-0.80.6-0.91.0-0.81.01.0-0.71.31.11.1-1.1
Co content in liver1.31.62.3-1.11.0-1.21.2-1.41.21.3-0.91.21.51.5-1.5
Cu content in liver2.53.03.31.8-1.71.8-1.81.7-1.8-1.81.8-1.8-1.7-1.71.7
Fe content in liver1.11.31.61.1-1.11.1-1.11.2-1.1-1.11.1-1.0-1.3-1.31.3
K content in liver1.00.91.7-1.11.2-1.00.9-1.00.90.9-1.30.80.80.8-0.8
Mg content in liver0.20.20.5-0.40.5-0.40.4-0.30.40.3-0.70.50.40.4-0.4
Mn content in liver0.20.20.5-0.40.4-0.40.5-0.30.60.5-0.50.70.50.5-0.5
Na content in liver0.10.10.2-0.00.20.1-0.2-0.0-0.2-0.2-0.2-0.4-0.3-0.30.3
Rb content in liver0.40.50.8-0.50.3-0.60.7-0.60.70.8-0.30.90.90.9-0.9
Se content in liver0.00.00.00.1-0.10.1-0.10.1-0.1-0.10.0-0.1-0.1-0.10.1
Sr content in liver0.10.10.40.3-0.40.1-0.00.1-0.00.20.60.20.10.1-0.1
Zn content in liver0.00.00.10.2-0.30.1-0.10.1-0.00.00.30.10.30.3-0.3
Bone: minimum diameter0.40.81.2-0.80.7-0.91.0-0.71.01.1-0.51.11.01.0-1.0
Time in familiar zone, hab. session 10.00.00.10.0-0.10.0-0.0-0.0-0.10.10.3-0.1-0.0-0.00.0
Time in novel zone, hab. session 10.80.71.01.0-1.00.9-0.91.0-0.8-0.90.8-0.7-0.8-0.80.8
Total zone transitions, hab. session 10.50.71.00.9-1.00.9-0.81.0-0.8-0.80.9-0.6-0.8-0.80.8
Total locomotion distance, hab. session 10.00.10.30.0-0.1-0.10.20.20.30.3-0.00.50.30.3-0.3
Locomotion velocity, hab. session 10.40.61.0-0.60.5-0.70.7-0.50.80.8-0.71.00.80.8-0.8
Time in familiar zone, hab. session 20.30.30.8-0.80.9-0.60.5-0.60.50.4-0.80.20.40.4-0.4
Time in novel zone, hab. session 20.90.91.41.1-1.21.0-0.90.9-0.9-0.81.1-0.7-0.8-0.80.8
Total zone transitions, hab. session 20.20.20.50.4-0.40.5-0.40.2-0.5-0.40.5-0.7-0.4-0.40.4
Total locomotion distance, hab. session 20.20.30.6-0.50.4-0.50.6-0.50.60.7-0.20.60.70.7-0.7
Locomotion velocity, hab. session 20.40.50.9-0.60.5-0.70.8-0.70.70.9-0.40.80.80.8-0.8
Novel to familiar place preference ratio0.70.81.01.0-1.00.9-0.90.5-1.0-0.81.0-0.9-0.8-0.80.8
Novelty place preference0.80.81.31.1-1.11.0-1.00.6-1.0-0.81.1-0.9-0.7-0.70.7
Time in novel zone, NPP test0.30.30.50.7-0.70.6-0.60.3-0.6-0.50.7-0.6-0.4-0.40.4
Total zone transitions, NPP test0.50.81.1-0.90.9-0.80.9-1.00.80.9-0.70.70.90.9-0.9
Total locomotion distance, NPP test0.40.60.7-0.70.7-0.70.7-0.80.70.8-0.70.80.80.8-0.8
Locomotion velocity, NPP test0.30.40.5-0.50.4-0.50.6-0.60.60.6-0.50.70.70.7-0.7
Intraocular pressure0.20.30.80.7-0.80.6-0.60.4-0.5-0.90.7-0.4-0.0-0.00.0
Delta distance traveled before/after self-admin0.50.51.0-0.60.6-0.70.7-0.50.71.0-0.20.80.80.8-0.8
Delta ambulatory time before/after self-admin1.31.52.2-1.00.9-1.11.1-1.01.21.5-0.71.41.41.4-1.4
Parametrial fat weight0.10.20.30.4-0.50.4-0.40.5-0.4-0.40.5-0.4-0.3-0.30.3
Pavlov. Cond. lever latency0.10.10.3-0.0-0.1-0.20.30.00.30.50.20.50.40.4-0.4
Pavlov. Cond. magazine entry latency0.10.10.20.00.10.2-0.20.1-0.3-0.4-0.2-0.4-0.4-0.40.4
Pavlov. Cond. change in total contacts0.00.00.1-0.20.2-0.10.0-0.2-0.0-0.2-0.3-0.2-0.1-0.10.1
Pavlov. Cond. index score0.10.10.40.10.10.2-0.30.0-0.4-0.5-0.3-0.6-0.5-0.50.5
Pavlov. Cond. latency score0.10.10.30.00.10.2-0.3-0.0-0.3-0.4-0.2-0.5-0.4-0.40.4
Pavlov. Cond. lever contacts0.40.50.80.5-0.40.6-0.70.4-0.7-0.90.2-0.9-0.8-0.80.8
Pavlov. Cond. magazine entry number0.10.10.20.1-0.3-0.00.10.00.20.30.40.40.30.3-0.3
Pavlov. Cond. intertrial magazine entries8.910.811.8-3.33.2-3.33.3-3.43.23.2-2.93.13.43.4-3.4
Pavlov. Cond. lever-magazine prob. diff.0.10.10.30.00.10.2-0.3-0.0-0.3-0.4-0.3-0.5-0.5-0.50.5
Pavlov. Cond. response bias0.10.10.2-0.20.30.0-0.1-0.1-0.2-0.3-0.5-0.5-0.3-0.30.3
Pavlov. Cond. lever latency3.14.14.9-2.22.2-2.12.0-2.12.01.9-2.11.72.02.0-2.0
Pavlov. Cond. magazine entry latency3.84.45.02.1-2.12.1-2.12.0-2.1-1.92.2-2.1-2.2-2.22.2
Pavlov. Cond. change in total contacts6.38.69.73.0-3.03.0-2.92.9-2.9-2.83.1-2.8-2.9-2.92.9
Pavlov. Cond. index score4.86.26.82.5-2.62.5-2.52.4-2.5-2.32.6-2.4-2.5-2.52.5
Pavlov. Cond. latency score4.45.56.12.3-2.32.3-2.32.2-2.3-2.22.4-2.3-2.5-2.52.5
Pavlov. Cond. lever contacts3.44.65.22.3-2.32.2-2.22.1-2.1-2.02.2-2.0-2.2-2.22.2
Pavlov. Cond. magazine entry number3.34.05.6-2.02.1-2.01.9-1.92.01.8-2.42.02.02.0-2.0
Pavlov. Cond. intertrial magazine entries5.16.77.3-2.52.4-2.52.5-2.52.62.4-2.62.72.72.7-2.7
Pavlov. Cond. lever-magazine prob. diff.5.67.17.72.7-2.72.7-2.62.6-2.7-2.52.8-2.6-2.7-2.72.7
Pavlov. Cond. response bias3.54.85.32.3-2.32.2-2.22.2-2.2-2.02.3-2.0-2.2-2.22.2
Time in closed arm before self-admin8.09.011.03.1-3.23.1-3.03.1-3.0-3.32.8-2.8-2.9-2.92.9
Time in closed arm after self-admin5.85.98.42.8-2.92.6-2.52.9-2.4-2.42.4-2.0-2.1-2.12.1
Time in open arm before self-admin6.67.28.8-2.62.6-2.72.7-2.72.73.0-2.32.82.72.7-2.7
Time in open arm after self-admin9.810.813.1-3.63.6-3.43.4-3.63.33.3-3.22.93.03.0-3.0
Bone: periosteal estimation0.30.61.60.9-1.10.8-0.60.8-0.6-0.51.3-0.4-0.5-0.50.5
Bone: periosteal perimeter0.00.00.20.1-0.20.1-0.10.2-0.1-0.00.4-0.1-0.2-0.20.2
Bone: post-yield work2.02.73.2-1.71.6-1.71.8-1.51.81.6-1.51.71.51.5-1.5
Progressive ratio test 1 active lever presses0.00.00.10.3-0.40.2-0.20.2-0.2-0.10.2-0.10.00.0-0.0
Progressive ratio test 1 breakpoint0.10.10.20.4-0.40.3-0.30.3-0.3-0.20.2-0.2-0.1-0.10.1
Progressive ratio test 1 inactive lever presses2.62.84.0-1.51.4-1.61.6-1.51.71.5-1.41.82.02.0-2.0
Progressive ratio test 2 active lever presses0.00.00.10.2-0.20.2-0.10.4-0.1-0.00.3-0.1-0.1-0.10.1
Progressive ratio test 2 breakpoint0.00.00.10.1-0.10.0-0.00.30.00.10.10.10.10.1-0.1
Progressive ratio test 2 inactive lever presses0.10.20.40.0-0.1-0.10.20.00.30.60.20.50.60.6-0.6
Incentive Sensitization - Responses0.10.10.30.4-0.40.3-0.30.5-0.3-0.20.6-0.1-0.2-0.20.2
Incentive Sensitization - Breakpoint0.10.10.30.4-0.40.3-0.20.4-0.2-0.10.5-0.1-0.1-0.10.1
Sum of active levers in priming session hrs 5-60.30.30.60.4-0.40.5-0.50.4-0.6-0.50.5-0.8-0.7-0.70.7
Progressive ratio0.91.12.51.4-1.61.2-1.11.5-1.0-0.61.1-0.5-0.4-0.40.4
Food seeking constrained by brief footshock0.10.20.5-0.1-0.1-0.20.2-0.10.30.30.10.40.70.7-0.7
Seeking ratio, punishment vs. effort0.70.91.7-1.21.2-1.11.1-1.30.90.7-0.80.70.80.8-0.8
Retroperitoneal fat weight0.00.10.40.3-0.30.4-0.40.2-0.5-0.50.3-0.6-0.2-0.20.2
Reaction time number correct4.46.36.7-2.52.5-2.52.6-2.62.52.4-2.42.52.52.5-2.5
Reaction time mean minus median0.00.00.10.2-0.20.2-0.20.2-0.2-0.30.1-0.20.00.0-0.0
Reaction time mean minus median AUC0.00.00.10.2-0.20.1-0.10.0-0.1-0.20.1-0.00.30.3-0.3
Reaction time num false alarms2.02.73.1-1.61.6-1.61.6-1.61.61.4-1.61.61.81.8-1.8
Reaction time num false alarms AUC2.23.03.4-1.71.7-1.71.7-1.61.71.5-1.81.71.81.8-1.8
Reaction time trials correct on left4.46.36.7-2.52.5-2.52.6-2.62.52.4-2.42.52.52.5-2.5
Reaction time trials on left4.46.36.7-2.52.5-2.62.6-2.62.52.4-2.42.52.62.6-2.6
Reaction time mean1.72.43.31.8-1.81.7-1.71.7-1.6-1.61.5-1.3-1.2-1.21.2
Reaction time mean AUC1.01.42.01.4-1.41.3-1.31.3-1.2-1.21.1-1.0-0.8-0.80.8
Median of all reaction times1.52.03.01.7-1.71.6-1.61.6-1.4-1.41.4-1.1-1.0-1.01.0
Reaction time omissions1.21.62.6-1.01.0-1.11.2-1.01.31.1-1.01.51.61.6-1.6
Reaction time false alarm rate0.10.20.3-0.40.4-0.40.4-0.30.40.3-0.50.50.60.6-0.6
Reaction time premature initiation rate0.20.30.5-0.40.4-0.50.5-0.60.50.7-0.40.60.50.5-0.5
Reaction time premature initiations2.23.23.9-1.81.7-1.81.8-2.01.81.9-1.71.81.71.7-1.7
Std. dev. reaction times1.01.42.21.4-1.51.3-1.31.3-1.2-1.31.2-1.0-0.8-0.80.8
Reaction time trials completed4.46.36.7-2.52.5-2.62.6-2.62.52.4-2.42.52.62.6-2.6
Reaction time trials AUC4.66.66.9-2.62.5-2.62.6-2.62.62.5-2.52.52.62.6-2.6
Run reversals in cocaine runway, females2.62.53.31.8-1.81.7-1.71.5-1.7-1.11.5-1.6-1.5-1.51.5
Run reversals in cocaine runway, males0.00.00.10.2-0.20.1-0.10.4-0.1-0.20.40.0-0.1-0.10.1
Latency to leave start box in cocaine runway0.80.91.91.0-1.11.0-1.01.0-0.9-1.01.4-0.8-0.5-0.50.5
Latency to leave start box in cocaine runway, F0.30.40.50.6-0.50.6-0.60.6-0.7-0.60.5-0.7-0.6-0.60.6
Latency to leave start box in cocaine runway, M0.70.72.00.9-1.00.9-0.80.7-0.8-0.91.4-0.7-0.3-0.30.3
Std. dev. time between licks in bursts0.10.10.2-0.30.2-0.30.3-0.40.30.4-0.10.20.30.3-0.3
Total sessions with >9 infusions0.00.00.00.2-0.20.2-0.20.1-0.10.20.0-0.10.00.0-0.0
Short access day 1 total inactive lever presses0.00.00.10.2-0.20.2-0.10.4-0.10.20.10.10.10.1-0.1
Short access day 10 total inactive lever presses0.30.40.8-0.30.3-0.50.5-0.40.60.6-0.50.80.90.9-0.9
Short access day 1 total infusions0.00.00.10.1-0.1-0.00.10.20.10.3-0.00.30.30.3-0.3
Short access day 10 total infusions0.20.20.40.5-0.60.5-0.50.7-0.5-0.20.4-0.5-0.5-0.50.5
Short access total infusions0.60.61.20.9-1.00.9-0.81.1-0.8-0.60.9-0.6-0.6-0.60.6
Short access day 1 locomotion0.40.40.60.7-0.70.7-0.70.6-0.7-0.80.4-0.6-0.5-0.50.5
Short access day 10 total locomotion0.00.00.1-0.00.10.1-0.1-0.1-0.2-0.2-0.1-0.3-0.3-0.30.3
Short access total locomotion0.00.00.10.2-0.20.2-0.10.3-0.1-0.1-0.0-0.1-0.1-0.10.1
One hour access (0.3 mA shock)0.50.50.7-0.80.8-0.80.8-0.80.70.7-0.70.60.70.7-0.7
Compulsive drug intake0.40.40.9-0.91.0-0.80.7-0.80.70.2-0.80.50.40.4-0.4
One hour access (shock baseline)0.10.10.20.4-0.40.3-0.30.2-0.30.10.5-0.3-0.0-0.00.0
Social response proportion0.30.30.90.7-0.80.6-0.61.0-0.4-0.70.4-0.0-0.4-0.40.4
Social responses0.40.50.80.8-0.90.8-0.70.8-0.6-0.80.8-0.5-0.4-0.40.4
Social time0.20.30.70.2-0.3-0.10.20.20.40.30.10.80.80.8-0.8
Soleus weight1.95.67.9-2.72.8-2.52.4-2.82.22.2-2.51.72.12.1-2.1
Bone: stiffness0.91.51.9-1.21.1-1.31.4-1.21.31.3-0.81.31.21.2-1.2
Tibialis anterior weight0.93.14.3-1.91.8-1.81.8-2.11.71.8-1.51.51.71.7-1.7
Time to tail flick, vehicle, before self-admin2.42.43.1-1.61.7-1.61.5-1.71.51.5-1.81.31.51.5-1.5
Time to tail flick, vehicle, after self-admin0.70.81.2-1.11.1-1.00.9-1.00.90.8-1.00.70.70.7-0.7
Time to tail flick, test, before self-admin0.10.10.20.3-0.40.3-0.20.2-0.2-0.30.4-0.10.20.2-0.2
Time to tail flick, test, after self-admin4.74.86.9-2.42.5-2.32.3-2.32.22.3-2.62.01.71.7-1.7
Delta time to tail flick, vehicle, before/after SA0.10.10.2-0.40.5-0.40.4-0.40.40.3-0.20.30.20.2-0.2
Delta time to tail flick, test, before/after SA4.84.36.3-2.32.3-2.22.2-2.22.12.0-2.51.91.71.7-1.7
Tibia length0.10.20.5-0.50.5-0.50.5-0.30.50.4-0.70.60.30.3-0.3
Ambulatory time before self-admin1.31.31.81.1-1.01.1-1.11.2-1.1-1.11.3-1.2-1.2-1.21.2
Ambulatory time after self-admin0.20.20.60.4-0.50.4-0.40.7-0.3-0.30.8-0.2-0.2-0.20.2
Bone: tissue strength0.30.30.60.6-0.60.5-0.50.8-0.4-0.50.5-0.3-0.5-0.50.5
Total heroin consumption2.12.53.5-1.81.9-1.71.7-1.71.51.5-1.71.21.41.4-1.4
Bone: trabecular number0.30.40.7-0.70.6-0.70.7-0.80.70.7-0.50.70.60.6-0.6
Bone: trabecular spacing0.00.00.10.2-0.20.3-0.30.2-0.3-0.20.0-0.3-0.2-0.20.2
Bone: trabecular thickness0.10.10.1-0.20.3-0.30.2-0.30.30.2-0.30.30.20.2-0.2
Bone: trabecular tissue density0.00.00.0-0.00.1-0.0-0.0-0.0-0.00.0-0.1-0.00.00.0-0.0
Water consumed over 24 hours1.51.72.4-1.11.0-1.31.4-1.01.41.4-0.91.51.51.5-1.5
Number of responses in last shaping day0.70.71.10.9-0.90.8-0.80.8-0.8-1.00.7-0.8-0.8-0.80.8