Gngt2

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Adipose intron excision ratio chr10_80782293_80783525 0.22 0.1 0.0e+00 0.16 0.14 0.16 0.16 3.5e-17 8.6e-16 6.2e-18 4.5e-17
2 Adipose alternative TSS XM_039086881.1 0.05 0.03 2.4e-08 0.06 0.06 0.06 0.06 1.1e-07 3.1e-07 2.5e-07 2.6e-07
3 PL gene expression Gngt2 0.02 0.02 5.4e-03 0.02 0.01 0.01 0.01 2.2e-03 2.2e-02 1.6e-02 1.0e-02
4 Adipose gene expression Gngt2 0.07 0.04 2.8e-11 0.08 0.08 0.07 0.07 2.3e-09 3.2e-09 1.3e-08 5.6e-08
5 Adipose isoform ratio XM_006247208.4 0.06 0.04 1.7e-09 0.07 0.04 0.06 0.01 6.3e-08 4.9e-05 1.0e-07 7.9e-03
6 Liver intron excision ratio chr10_80781203_80782211 0.02 0.02 3.4e-03 0.03 0.02 0.02 0.03 1.1e-04 5.9e-03 4.6e-03 2.5e-04
7 Liver intron excision ratio chr10_80781744_80782211 0.04 0.02 1.0e-05 0.06 0.04 0.04 0.05 9.6e-07 5.9e-05 4.3e-05 2.0e-06
8 Adipose alternative TSS XM_006247208.4 0.04 0.02 2.2e-06 0.05 0.04 0.05 0.03 1.8e-06 5.5e-05 2.7e-06 4.1e-04
9 Liver intron excision ratio chr10_80782293_80783530 0.28 0.1 0.0e+00 0.39 0.39 0.39 0.39 8.8e-46 1.1e-45 2.4e-46 4.5e-46
10 Liver intron excision ratio chr10_80782293_80783525 0.28 0.1 0.0e+00 0.39 0.39 0.39 0.39 6.2e-46 8.9e-46 2.6e-46 5.7e-46
11 Liver isoform ratio XM_039086880.1 0.17 0.08 0.0e+00 0.28 0.28 0.29 0.29 5.3e-31 8.4e-32 6.6e-32 6.0e-32
12 Eye intron excision ratio chr10_80782293_80783530 0.31 0.18 4.9e-03 0.04 0.05 0.02 0.06 7.3e-02 6.3e-02 1.8e-01 5.0e-02
13 Eye intron excision ratio chr10_80782293_80783525 0.38 0.19 1.3e-03 0.07 0.07 0.06 0.08 3.5e-02 3.4e-02 4.6e-02 2.2e-02
14 pVTA intron excision ratio chr10_80782293_80783525 0.11 0.08 6.3e-04 0.05 0.04 0.05 -0.01 3.3e-03 6.0e-03 4.0e-03 8.1e-01
15 NAcc intron excision ratio chr10_80782293_80783525 0.12 0.09 2.0e-05 0.04 0.03 0.03 0.04 1.2e-05 1.5e-04 5.9e-04 8.8e-06
16 Liver isoform ratio NM_001135767.1 0.14 0.07 0.0e+00 0.22 0.21 0.21 0.22 1.2e-23 1.7e-22 8.0e-23 1.3e-23
17 Adipose isoform ratio XM_039086880.1 0.05 0.04 8.5e-07 0.06 0.06 0.06 0.06 3.8e-07 7.4e-07 2.0e-07 9.7e-08
18 Adipose alternative TSS XM_006247209.2 0.03 0.02 9.9e-06 0.04 0.04 0.03 0.03 4.2e-05 3.3e-05 2.6e-04 6.1e-04
19 PL intron excision ratio chr10_80782293_80783525 0.05 0.03 8.9e-07 0.05 0.06 0.05 0.05 8.2e-06 6.9e-07 2.0e-06 1.6e-06
20 BLA intron excision ratio chr10_80782293_80783525 0.08 0.06 3.4e-05 0.08 0.09 0.08 0.08 3.1e-05 2.7e-05 6.5e-05 6.0e-05
21 Brain intron excision ratio chr10_80782293_80783525 0.06 0.04 1.5e-07 0.06 0.06 0.06 0.06 7.5e-06 1.6e-06 4.8e-06 2.4e-06
22 PL alternative TSS XM_006247209.2 0.02 0.02 4.6e-03 0.01 0.02 0 0.01 2.6e-02 3.9e-03 2.3e-01 1.7e-02
23 Adipose alternative TSS XM_039086880.1 0.02 0.02 2.0e-03 0.03 0.02 0.03 0.03 1.5e-04 2.2e-03 3.2e-04 2.8e-04
24 PL alternative TSS XM_006247208.4 0.02 0.02 5.9e-03 0.01 0.01 0 0.01 1.1e-02 4.4e-02 8.4e-02 3.2e-02

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bone: apparent density1.01.73.3-1.3-1.81.21.2-1.41.4-1.4-1.41.2-1.2-1.2-1.31.3-1.11.1-1.1-1.5-1.21.31.21.2-1.11.8-0.7
Area under the delay curve0.00.00.20.20.2-0.0-0.1-0.1-0.00.00.0-0.10.0-0.00.1-0.1-0.10.0-0.10.10.0-0.1-0.0-0.0-0.0-0.0-0.4
BMI with tail14.647.255.2-6.7-7.07.17.1-7.37.4-7.4-7.47.2-7.2-7.3-6.96.9-7.27.3-7.2-6.9-7.07.26.56.3-6.05.9-3.2
BMI without tail0.61.22.0-1.1-1.41.21.0-1.11.1-1.1-1.11.1-1.1-1.2-1.01.0-1.11.2-1.2-1.3-1.11.20.80.8-0.61.10.1
Body weight0.83.55.9-1.8-2.21.71.7-1.92.0-2.0-2.01.8-1.8-1.7-1.71.7-1.71.8-1.6-2.2-1.92.01.91.9-1.82.4-1.5
Weight adjusted by age0.10.10.20.1-0.2-0.2-0.20.2-0.10.10.1-0.30.30.30.4-0.40.3-0.10.4-0.10.3-0.3-0.3-0.30.20.2-0.0
Bone surface0.30.51.6-0.6-1.00.60.6-0.80.8-0.8-0.80.6-0.6-0.6-0.60.6-0.50.5-0.5-0.9-0.70.70.70.7-0.71.3-0.9
Bone volume0.81.43.4-1.1-1.61.01.0-1.31.3-1.3-1.31.0-1.0-1.0-1.11.1-0.90.9-0.8-1.4-1.11.31.31.2-1.21.9-1.4
Breakpoint value in progressive ratio session2.52.74.31.41.4-2.0-1.92.1-2.12.12.1-1.61.61.61.4-1.41.5-1.41.21.31.7-1.8-1.7-1.61.5-1.31.6
Number of licking bursts1.41.73.61.51.7-1.0-1.11.0-1.01.01.0-1.31.31.21.2-1.21.3-1.31.31.71.2-1.2-1.3-1.31.4-1.91.4
Context. condit. distance diff. score0.91.11.6-1.1-1.31.21.1-1.21.2-1.2-1.21.1-1.1-1.1-1.01.0-0.91.0-1.0-1.1-1.01.01.01.0-0.91.0-0.5
Locomotion velocity, session 10.10.10.60.20.5-0.1-0.20.2-0.20.20.2-0.30.30.30.1-0.10.2-0.40.50.30.3-0.3-0.3-0.40.4-0.20.8
Locomotion distance, session 14.86.16.82.52.6-2.6-2.62.6-2.62.62.6-2.62.52.62.5-2.52.4-2.62.52.42.5-2.5-2.4-2.42.4-1.81.9
Locomotion velocity, session 20.91.01.61.01.2-1.2-1.21.2-1.21.21.2-1.11.11.11.1-1.11.0-1.11.00.71.0-1.0-0.8-0.80.7-0.3-0.1
Locomotion distance, session 26.69.211.53.23.4-3.2-3.13.1-3.13.13.1-3.13.03.12.9-2.92.8-3.03.03.13.0-3.1-3.0-3.03.0-2.82.7
Locomotion velocity, session 30.70.92.2-1.0-0.90.70.7-0.50.5-0.5-0.50.9-0.9-0.9-0.70.7-1.10.9-1.1-1.0-0.90.91.01.1-1.11.2-1.5
Locomotion distance, session 31.11.21.61.01.1-1.2-1.21.2-1.31.31.3-1.11.11.11.1-1.11.0-1.01.00.91.1-1.1-1.1-1.01.0-0.60.7
Stereotopy head waving bouts, day 34.24.96.0-2.4-2.32.22.2-2.02.0-2.0-2.02.3-2.3-2.3-2.22.2-2.32.4-2.4-2.4-2.32.32.22.3-2.32.2-1.7
Stereotopy head waving duration, day 33.13.74.3-2.1-2.12.01.9-1.81.9-1.9-1.91.9-1.9-1.9-1.91.9-1.81.9-1.9-1.9-2.02.02.02.0-2.01.8-1.8
Locomotion velocity, session 71.21.32.01.41.1-1.2-1.31.1-1.11.11.1-1.21.21.21.3-1.31.1-1.21.21.21.1-1.0-0.9-0.90.9-1.00.4
Locomotion distance, session 76.68.411.33.43.0-3.1-3.12.8-2.82.82.8-3.03.03.03.1-3.12.9-3.03.03.02.9-2.8-2.7-2.72.7-2.82.0
Stereotopy head waving bouts, day 70.50.51.0-1.0-0.90.70.8-0.50.5-0.5-0.50.8-0.8-0.7-0.80.8-0.70.8-0.8-0.8-0.70.70.70.7-0.80.8-0.4
Stereotopy head waving duration, day 70.40.51.2-1.1-0.80.60.7-0.30.3-0.3-0.30.7-0.7-0.6-0.70.7-0.70.7-0.8-0.7-0.70.60.70.8-0.80.8-0.6
Locomotion velocity, session 80.91.01.7-1.2-1.31.01.0-0.90.9-0.9-0.91.1-1.1-1.0-1.11.1-1.11.1-1.1-1.3-1.00.80.80.9-1.01.3-0.4
Locomotion distance, session 80.60.81.40.90.9-0.8-0.90.9-0.90.90.9-0.90.90.90.8-0.80.8-0.90.90.90.9-1.0-1.0-1.00.9-0.81.2
Degree of sensitization distance0.30.31.11.00.8-0.6-0.60.3-0.30.30.3-0.60.60.60.6-0.60.6-0.60.70.80.5-0.4-0.3-0.40.5-1.00.2
Degree of sensitization stereotypy0.20.20.70.30.3-0.5-0.40.6-0.60.60.6-0.40.40.40.4-0.40.4-0.40.40.50.5-0.5-0.5-0.50.5-0.50.8
Conditioned locomotion1.72.03.4-1.0-0.81.71.7-1.81.8-1.8-1.81.4-1.4-1.5-1.51.5-1.31.2-1.3-0.9-1.41.41.41.3-1.30.5-1.0
Cocaine response after cond. corrected5.25.97.0-2.4-2.42.62.6-2.62.6-2.6-2.62.6-2.6-2.6-2.62.6-2.42.5-2.6-2.3-2.52.42.22.2-2.11.7-1.2
Cocaine response after cond. not corrected3.13.44.4-1.8-1.72.02.0-2.01.9-1.9-1.92.0-2.0-2.0-2.02.0-1.92.0-2.1-1.8-1.91.81.61.6-1.61.2-0.9
Cocaine response before conditioning2.42.93.81.81.9-1.8-1.91.9-1.91.91.9-1.71.71.71.8-1.81.5-1.61.51.61.7-1.8-1.7-1.61.6-1.51.0
Saline control response0.20.31.60.40.90.40.4-0.50.5-0.5-0.5-0.00.0-0.1-0.20.20.1-0.20.20.80.00.0-0.1-0.30.4-1.31.2
Bone: connectivity density0.30.41.5-0.6-1.20.50.5-0.70.7-0.7-0.70.6-0.6-0.6-0.50.5-0.50.6-0.5-0.9-0.50.60.40.4-0.41.1-0.3
Bone: cortical apparent density4.45.87.22.32.0-2.5-2.52.6-2.72.72.7-2.52.52.62.6-2.62.5-2.52.52.42.5-2.4-2.3-2.22.1-2.21.3
Bone: cortical area0.30.50.7-0.4-0.60.60.6-0.90.8-0.8-0.80.6-0.6-0.6-0.70.7-0.60.6-0.6-0.6-0.70.80.80.8-0.70.5-0.8
Bone: cortical porosity0.30.30.7-0.4-0.30.50.5-0.60.6-0.6-0.60.5-0.6-0.6-0.50.5-0.60.5-0.6-0.7-0.60.60.60.6-0.50.8-0.5
Bone: cortical porosity0.20.20.4-0.3-0.10.30.3-0.40.4-0.4-0.40.4-0.4-0.4-0.40.4-0.40.3-0.4-0.4-0.40.50.50.4-0.40.6-0.4
Bone: cortical thickness0.20.30.7-0.4-0.60.40.4-0.60.6-0.6-0.60.5-0.5-0.5-0.50.5-0.50.5-0.5-0.5-0.60.60.70.7-0.70.4-0.8
Bone: cortical thickness0.20.30.60.4-0.3-0.7-0.70.6-0.50.50.5-0.50.50.50.7-0.70.5-0.40.40.20.6-0.6-0.7-0.60.5-0.00.2
Bone: cortical tissue density4.96.58.02.42.2-2.7-2.72.8-2.82.82.8-2.62.62.72.7-2.72.7-2.62.62.52.6-2.6-2.4-2.32.3-2.31.4
Condit. Reinf. active minus inactive responses1.11.21.81.31.1-1.2-1.21.0-1.11.11.1-1.11.11.11.4-1.41.0-1.01.00.81.1-1.1-1.1-1.11.2-0.60.8
Condit. Reinf. active-inactive response ratio0.00.00.20.1-0.2-0.00.0-0.20.2-0.2-0.20.2-0.2-0.20.0-0.0-0.30.3-0.2-0.4-0.10.20.00.10.00.40.2
Condit. Reinf. active responses1.21.52.01.21.2-1.3-1.31.2-1.31.31.3-1.21.21.21.4-1.41.2-1.21.10.91.3-1.2-1.3-1.31.3-0.71.0
Condit. Reinf. inactive responses1.31.52.00.71.4-0.9-1.01.3-1.41.41.4-1.21.21.21.1-1.11.4-1.31.31.31.2-1.3-1.3-1.31.3-1.11.2
Incentive salience index mean2.02.43.01.71.6-1.6-1.61.5-1.51.51.5-1.61.61.51.7-1.71.5-1.51.51.31.6-1.6-1.7-1.71.7-1.11.5
Condit. Reinf. lever presses2.83.85.22.02.3-1.8-1.81.8-1.91.91.9-1.91.91.91.8-1.81.9-1.92.02.02.0-2.0-2.0-2.12.1-1.92.2
Condit. Reinf. active minus inactive responses0.30.41.40.60.6-0.4-0.40.4-0.40.40.4-0.60.60.50.5-0.50.6-0.60.70.70.6-0.5-0.7-0.70.8-0.81.2
Condit. Reinf. active-inactive response ratio0.60.63.20.80.9-0.4-0.50.5-0.40.40.4-0.60.60.50.5-0.50.7-0.60.60.90.7-0.7-1.0-1.11.2-1.21.8
Condit. Reinf. active responses0.10.20.40.40.3-0.3-0.40.4-0.30.30.3-0.50.50.50.4-0.40.6-0.50.60.40.5-0.4-0.4-0.50.6-0.10.6
Condit. Reinf. inactive responses0.10.10.5-0.2-0.30.10.1-0.10.1-0.1-0.10.1-0.1-0.0-0.00.00.0-0.00.0-0.3-0.20.20.30.3-0.40.7-0.6
Condit. Reinf. lever presses0.20.30.70.20.2-0.5-0.50.7-0.60.60.6-0.60.70.60.5-0.50.8-0.80.70.40.6-0.6-0.5-0.50.40.0-0.1
Condit. Reinf. lever reinforcers received0.20.20.50.40.2-0.4-0.40.4-0.40.40.4-0.50.60.50.5-0.50.7-0.60.70.40.5-0.4-0.5-0.50.6-0.00.6
Conditioned reinforcement - actives0.40.40.80.40.5-0.5-0.50.7-0.50.50.5-0.60.60.60.7-0.70.7-0.70.70.80.6-0.4-0.5-0.60.7-0.90.7
Conditioned reinforcement - inactives0.20.20.50.50.7-0.3-0.30.4-0.00.00.0-0.40.40.30.5-0.50.6-0.60.50.60.4-0.3-0.3-0.40.6-0.70.5
Conditioned locomotion0.10.10.3-0.20.10.50.5-0.40.2-0.2-0.20.1-0.1-0.1-0.30.3-0.1-0.00.10.2-0.20.20.10.00.1-0.50.6
Patch foraging indifference point 0 sec1.72.74.0-1.8-1.41.81.8-1.61.8-1.8-1.81.7-1.7-1.7-1.61.6-1.71.6-1.6-1.8-1.61.41.51.5-1.62.0-1.5
Patch foraging indifference point AUC0.00.00.10.10.2-0.1-0.10.1-0.20.20.2-0.20.20.10.3-0.30.3-0.20.10.20.1-0.1-0.1-0.10.1-0.20.1
Delay disc. indifference point, 0s delay0.00.00.20.20.40.20.2-0.40.3-0.3-0.3-0.00.1-0.0-0.20.20.1-0.10.20.3-0.00.00.10.0-0.0-0.1-0.5
Delay disc. indifference point, 16s delay1.41.41.9-1.2-1.21.11.0-1.11.0-1.0-1.01.2-1.2-1.2-1.01.0-1.41.4-1.4-1.3-1.21.21.21.2-1.31.2-1.0
Delay disc. indifference point, 2s delay0.10.20.50.60.5-0.0-0.20.0-0.00.00.0-0.50.60.40.3-0.30.6-0.60.70.60.3-0.3-0.1-0.20.2-0.3-0.3
Delay disc. indifference point, 24s delay0.80.71.21.10.9-1.1-1.10.8-0.90.90.9-0.80.80.81.1-1.10.8-0.60.60.70.8-0.9-0.9-0.80.8-0.70.5
Delay disc. indifference point, 4s delay0.80.81.41.20.9-1.0-1.20.9-0.90.90.9-1.11.11.00.9-0.90.9-0.91.00.90.9-0.9-0.7-0.70.6-0.5-0.4
Delay disc. indifference point, 8s delay0.10.10.10.30.4-0.2-0.30.2-0.30.30.3-0.20.20.20.4-0.40.1-0.20.00.20.2-0.3-0.2-0.20.2-0.2-0.2
Indifference point function ln k0.00.00.10.10.0-0.3-0.20.2-0.10.10.1-0.10.10.20.0-0.00.0-0.00.20.10.1-0.2-0.2-0.20.1-0.10.2
Indifference point function log k0.00.00.10.10.0-0.3-0.20.2-0.10.10.1-0.10.10.20.0-0.00.0-0.00.20.10.1-0.2-0.2-0.20.1-0.10.2
Patch foraging total patch changes 0 sec1.93.04.2-1.9-1.41.91.8-1.71.9-1.9-1.91.8-1.8-1.8-1.61.6-1.71.6-1.7-1.8-1.71.61.61.6-1.72.1-1.6
Patch foraging total patch changes 12 sec0.10.10.3-0.20.40.50.4-0.40.4-0.4-0.40.2-0.2-0.3-0.00.00.0-0.0-0.3-0.1-0.10.20.20.1-0.00.3-0.0
Patch foraging total patch changes 18 sec2.63.34.2-1.8-1.42.11.9-1.91.9-1.9-1.91.9-1.9-2.0-1.81.8-1.81.7-2.0-1.8-1.81.81.81.8-1.81.9-1.6
Patch foraging total patch changes 24 sec1.31.62.2-1.4-1.11.41.4-1.31.3-1.3-1.31.3-1.3-1.4-1.21.2-1.11.2-1.3-1.4-1.21.21.11.2-1.21.5-0.8
Patch foraging total patch changes 6 sec1.11.72.2-1.3-1.11.51.4-1.31.4-1.4-1.41.4-1.4-1.4-1.01.0-1.31.3-1.4-1.4-1.31.31.21.3-1.21.4-1.1
Patch foraging time to switch 0 sec0.10.20.50.70.5-0.2-0.30.1-0.20.20.2-0.30.30.30.6-0.60.3-0.50.30.60.4-0.4-0.5-0.50.5-0.60.5
Patch foraging water rate 0 sec1.93.14.3-2.1-2.01.71.7-1.51.7-1.7-1.71.8-1.8-1.7-1.81.8-1.71.9-1.8-2.0-1.81.81.71.8-1.72.0-1.4
Patch foraging water rate 12 sec0.71.12.3-1.2-1.20.80.8-0.60.7-0.7-0.70.9-1.0-0.9-1.11.1-1.11.1-1.0-1.3-1.11.01.01.1-1.11.5-1.0
Patch foraging water rate 18 sec0.00.00.1-0.00.20.00.10.00.0-0.0-0.0-0.10.1-0.0-0.10.10.10.10.00.0-0.10.10.10.1-0.0-0.30.1
Patch foraging water rate 24 sec1.41.92.3-1.5-1.21.41.4-1.21.5-1.5-1.51.3-1.4-1.4-1.51.5-1.31.4-1.4-1.4-1.41.41.41.4-1.31.3-0.9
Patch foraging water rate 6 sec0.10.10.5-0.6-0.70.20.2-0.00.2-0.2-0.20.3-0.4-0.3-0.50.5-0.40.5-0.4-0.3-0.30.2-0.00.1-0.10.10.7
Seeking ratio, delayed vs. immediate footshock1.82.13.5-1.9-1.41.61.8-1.61.6-1.6-1.61.5-1.4-1.4-1.31.3-1.21.3-1.2-1.4-1.41.41.41.3-1.31.5-1.3
Distance traveled before self-admin3.53.77.02.11.9-1.8-1.81.7-1.61.61.6-1.81.81.71.9-1.91.9-1.91.82.11.9-1.8-2.0-2.02.1-2.32.7
Distance traveled after self-admin0.10.10.5-0.4-0.70.20.3-0.30.3-0.3-0.30.4-0.5-0.4-0.30.3-0.50.5-0.4-0.4-0.30.3-0.1-0.00.10.20.4
Extensor digitorum longus weight0.93.75.7-2.1-2.41.91.8-1.91.9-1.9-1.91.9-1.9-1.8-1.71.7-1.81.8-1.8-2.0-1.92.02.02.0-2.02.1-2.1
Bone: elastic displacement0.00.00.1-0.1-0.20.10.1-0.20.2-0.2-0.20.1-0.1-0.1-0.10.10.00.00.0-0.0-0.10.10.0-0.00.1-0.00.2
Bone: elastic work0.00.00.1-0.3-0.20.20.2-0.10.2-0.2-0.2-0.00.10.1-0.10.10.3-0.30.3-0.00.00.00.0-0.00.10.30.1
Bone: endosteal estimation0.00.00.10.0-0.10.20.1-0.20.1-0.1-0.1-0.00.00.0-0.10.10.2-0.20.20.1-0.10.10.10.0-0.0-0.1-0.1
Bone: endosteal perimeter0.10.20.4-0.1-0.20.50.4-0.70.6-0.6-0.60.4-0.4-0.4-0.50.5-0.30.3-0.3-0.3-0.40.40.50.4-0.40.3-0.4
Epididymis fat weight0.00.10.20.0-0.20.10.0-0.20.4-0.4-0.40.1-0.1-0.2-0.30.3-0.20.2-0.1-0.2-0.30.40.30.3-0.10.10.0
Delta time in closed arm before/after self-admin0.20.21.5-0.2-0.30.20.2-0.40.4-0.4-0.40.3-0.2-0.3-0.30.3-0.10.2-0.2-0.6-0.30.40.50.4-0.40.8-1.2
Delta time in open arm before/after self-admin0.00.00.10.2-0.20.0-0.0-0.1-0.00.00.00.00.0-0.1-0.00.00.1-0.1-0.10.10.1-0.1-0.1-0.1-0.0-0.10.2
Diff in mean of infusions in LGA sessions1.92.13.01.51.2-1.7-1.71.5-1.41.41.4-1.51.51.51.0-1.01.5-1.41.41.31.5-1.4-1.5-1.51.5-1.31.7
Delay discount exponential model param0.00.00.2-0.4-0.20.20.3-0.10.2-0.2-0.20.2-0.2-0.1-0.30.3-0.10.1-0.0-0.2-0.20.20.20.1-0.10.10.3
Extinction: sum of active levers before priming1.21.22.01.41.2-1.1-1.21.0-0.70.70.7-1.31.31.11.1-1.11.4-1.31.31.21.1-1.0-0.8-0.90.9-1.00.2
Active lever presses in extinction session 60.20.20.5-0.5-0.40.10.2-0.10.1-0.1-0.10.4-0.4-0.4-0.40.4-0.50.7-0.7-0.7-0.30.20.10.2-0.30.6-0.3
Bone: final force0.00.10.2-0.0-0.20.20.2-0.40.4-0.4-0.40.1-0.1-0.2-0.30.30.0-0.0-0.0-0.1-0.20.30.20.2-0.00.30.1
Bone: final moment0.10.10.3-0.2-0.40.40.4-0.50.5-0.5-0.50.3-0.3-0.3-0.50.5-0.20.2-0.2-0.3-0.40.50.40.3-0.20.40.1
Food consumed during 24 hour testing period1.92.32.61.51.4-1.6-1.61.6-1.61.61.6-1.61.61.61.6-1.61.6-1.61.61.61.5-1.5-1.5-1.51.5-1.61.0
Glucose0.91.42.8-1.2-1.31.21.1-1.11.1-1.1-1.11.1-1.1-1.1-1.11.1-0.90.9-1.0-1.2-1.21.31.41.4-1.41.3-1.7
Heart weight0.91.22.7-1.0-1.10.91.0-1.11.3-1.3-1.30.9-0.9-1.0-0.90.9-0.90.9-0.7-1.2-1.11.31.21.1-1.01.6-1.2
Delay discount hyperbolic model param0.10.10.3-0.5-0.30.20.4-0.20.2-0.2-0.20.3-0.3-0.2-0.40.4-0.20.2-0.2-0.3-0.30.30.20.2-0.20.10.4
Intermittent access intake day 1-15 change0.80.81.2-0.9-0.91.01.0-1.11.1-1.1-1.11.0-1.0-1.0-0.90.9-1.00.9-0.9-0.7-0.90.80.70.7-0.80.6-0.4
Intermittent access intake escalation0.40.40.6-0.6-0.70.70.7-0.80.8-0.8-0.80.7-0.7-0.7-0.60.6-0.80.6-0.6-0.5-0.60.50.50.5-0.60.4-0.4
Intermittent access intake escalation 20.60.61.2-0.7-0.91.01.0-1.10.9-0.9-0.90.9-0.9-0.9-0.90.9-0.90.8-0.8-0.6-0.80.70.50.5-0.50.5-0.2
Intermitt. access day 1 inactive lever presses0.00.00.6-0.00.1-0.1-0.00.1-0.10.10.10.00.0-0.00.1-0.10.1-0.1-0.10.10.1-0.1-0.3-0.30.4-0.30.8
Intermitt. access day 15 inactive lever presses1.92.12.4-1.5-1.41.41.3-1.21.5-1.5-1.51.4-1.4-1.5-1.41.4-1.41.5-1.5-1.6-1.41.41.41.5-1.51.5-1.5
Intermitt. access escalation Index0.20.10.30.40.3-0.3-0.30.2-0.40.40.4-0.30.30.40.2-0.20.3-0.30.30.40.4-0.4-0.5-0.50.4-0.40.6
Intermittent access day 1 total infusions1.11.32.01.21.1-1.2-1.21.2-1.21.21.2-1.31.31.31.4-1.41.4-1.31.41.01.1-0.9-0.8-0.91.0-0.80.2
Intermittent access day 15 total infusions0.60.71.20.90.9-0.7-0.80.8-0.70.70.7-0.90.90.91.0-1.00.9-1.01.10.90.8-0.7-0.7-0.70.8-0.80.5
Intermittent access terminal intake (last 3 days)0.30.30.70.60.6-0.4-0.50.4-0.30.30.3-0.60.60.60.7-0.70.7-0.80.90.70.5-0.4-0.4-0.50.6-0.70.3
Intermittent access total infusions0.40.40.90.70.7-0.6-0.60.6-0.40.40.4-0.70.80.70.9-0.90.9-0.81.00.70.6-0.4-0.4-0.40.6-0.70.2
Intermittent access day 1 locomotion2.72.83.61.81.9-1.7-1.71.6-1.71.71.7-1.81.81.81.7-1.71.8-1.81.91.61.6-1.5-1.4-1.51.5-1.50.7
Intermittent access day 15 total locomotion0.70.81.31.11.2-0.9-0.90.8-0.60.60.6-1.01.00.91.0-1.00.9-1.01.11.10.8-0.7-0.6-0.70.8-1.10.3
Intermittent access total locomotion1.01.11.81.21.3-1.0-1.01.0-0.90.90.9-1.21.21.11.1-1.11.2-1.21.31.31.0-0.8-0.8-0.91.0-1.30.5
Intermittent access standard deviation0.70.71.2-0.8-0.70.90.9-0.91.1-1.1-1.10.8-0.8-0.9-0.90.9-0.90.8-0.7-0.6-0.90.90.80.8-0.80.5-0.7
Left kidney weight0.00.11.2-0.2-0.3-0.10.00.1-0.00.00.0-0.10.10.20.1-0.10.2-0.10.20.0-0.10.20.30.3-0.30.1-1.1
Right kidney weight0.61.74.1-1.6-1.41.31.4-1.21.2-1.2-1.21.1-1.1-1.0-1.41.4-0.90.9-0.7-1.1-1.31.31.51.5-1.51.3-2.0
Cocaine induced anxiety0.10.11.60.10.30.10.1-0.00.0-0.0-0.0-0.10.10.1-0.10.10.3-0.30.30.50.2-0.2-0.2-0.30.4-0.71.3
Post-drug Anxiety1.61.83.81.41.5-1.1-1.11.0-1.01.01.0-1.31.31.21.2-1.21.5-1.51.51.71.3-1.3-1.3-1.41.5-1.82.0
Baseline Anxiety0.00.00.20.2-0.0-0.1-0.1-0.10.2-0.2-0.2-0.0-0.0-0.10.0-0.0-0.10.1-0.1-0.1-0.10.10.20.2-0.20.1-0.5
Tail length14.644.250.56.66.5-7.0-7.17.1-7.17.17.1-7.07.07.17.0-7.07.1-7.17.06.36.8-6.8-6.3-6.15.9-5.13.2
Length with tail6.624.130.14.84.6-5.5-5.45.4-5.45.45.4-5.45.45.55.2-5.25.4-5.45.54.45.0-4.9-4.3-4.13.9-2.90.9
Length without tail0.10.11.7-0.1-0.1-0.2-0.0-0.00.1-0.1-0.1-0.00.00.1-0.10.10.0-0.00.2-0.3-0.20.30.50.5-0.60.7-1.3
Times rat made contact with spout0.91.12.41.11.3-1.0-0.91.0-1.01.01.0-1.11.11.00.9-0.91.1-1.01.11.30.9-0.9-0.8-0.90.9-1.50.5
Lifetime Intake0.40.40.80.60.7-0.6-0.60.6-0.60.60.6-0.70.70.70.8-0.80.8-0.80.90.70.6-0.5-0.5-0.50.5-0.60.3
Liver weight, left0.81.41.81.20.8-1.3-1.31.2-1.31.31.3-1.31.31.31.3-1.31.3-1.31.41.01.2-1.1-1.0-1.01.0-0.50.6
Liver weight, right0.50.81.41.10.3-1.2-1.10.8-0.70.70.7-1.01.01.01.1-1.11.2-1.21.10.80.8-0.6-0.5-0.40.5-0.6-0.8
Locomotor activity0.10.20.9-0.1-0.20.30.2-0.30.4-0.4-0.40.4-0.5-0.4-0.30.3-0.60.5-0.5-0.1-0.30.30.10.00.1-0.31.0
Locomotor testing distance0.20.41.8-0.4-0.30.80.7-0.70.9-0.9-0.90.7-0.7-0.7-0.50.5-0.80.6-0.6-0.1-0.50.50.20.1-0.0-0.31.3
Locomotor testing rearing0.10.21.8-0.1-0.30.30.3-0.40.6-0.6-0.60.3-0.3-0.4-0.10.1-0.20.2-0.3-0.0-0.10.1-0.3-0.30.3-0.21.4
Locomotion in novel chamber0.40.51.11.00.3-0.5-0.70.4-0.40.40.4-0.80.80.70.5-0.50.9-0.81.10.70.7-0.5-0.7-0.80.9-0.51.0
Locomotion in novel chamber post-restriction0.70.82.2-0.3-0.11.11.2-1.41.5-1.5-1.50.6-0.5-0.7-1.21.2-0.40.1-0.0-0.1-0.91.01.00.8-0.60.0-0.5
Fecal boli incidents, locomotor time 13.84.26.5-2.0-2.61.71.7-1.71.8-1.8-1.82.2-2.2-2.1-1.91.9-2.52.3-2.6-2.3-2.01.91.82.0-2.02.2-1.6
Change in fecal boli incidents, locomotor task2.42.33.51.61.4-1.4-1.51.4-1.41.41.4-1.71.71.61.5-1.51.8-1.71.91.61.5-1.4-1.4-1.41.5-1.40.9
Time >=10cm from walls, locomotor time 10.20.21.30.40.30.0-0.10.0-0.00.00.0-0.30.40.20.2-0.20.4-0.50.50.60.4-0.4-0.6-0.70.8-0.71.2
Bouts of movement, locomotor time 10.30.31.0-0.5-0.50.30.4-0.40.3-0.3-0.30.6-0.6-0.6-0.50.5-0.40.6-0.8-0.7-0.60.60.80.8-0.80.7-1.0
Total resting periods, locomotor time 10.70.81.5-0.9-0.80.60.7-0.70.6-0.6-0.60.9-0.9-0.9-0.90.9-0.81.0-1.1-1.1-0.91.01.11.1-1.11.0-1.2
Rest time, locomotor task time 10.10.20.4-0.2-0.20.30.4-0.40.4-0.4-0.40.4-0.4-0.4-0.50.5-0.20.3-0.4-0.2-0.40.40.50.5-0.50.3-0.6
Distance moved, locomotor task time 12.72.94.71.71.6-1.6-1.81.7-1.61.61.6-1.71.71.61.8-1.81.6-1.61.71.71.7-1.7-1.8-1.81.9-1.72.2
Vertical activity count, locomotor time 10.70.82.10.80.9-0.7-0.80.8-0.80.80.8-0.80.80.81.1-1.10.6-0.70.80.90.8-0.7-0.9-0.91.0-1.01.5
Time >=10cm from walls, locomotor time 20.50.51.21.10.8-0.6-0.80.5-0.40.40.4-0.70.70.60.7-0.70.6-0.70.60.80.7-0.7-0.8-0.80.8-0.90.7
Bouts of movement, locomotor time 20.10.10.40.20.00.30.2-0.40.5-0.5-0.5-0.00.1-0.10.2-0.20.6-0.40.20.10.00.00.0-0.10.1-0.10.3
Total resting periods, locomotor time 20.10.10.40.10.10.40.3-0.50.6-0.6-0.6-0.00.1-0.10.1-0.10.7-0.40.30.20.00.00.0-0.10.1-0.30.5
Rest time, locomotor task time 20.30.30.60.30.8-0.6-0.50.8-0.80.80.8-0.50.50.60.3-0.30.6-0.60.50.70.6-0.7-0.5-0.50.4-0.60.3
Distance moved, locomotor task time 20.10.20.40.40.2-0.4-0.70.5-0.50.50.5-0.40.40.40.6-0.60.2-0.20.30.10.4-0.3-0.3-0.20.20.0-0.2
Vertical activity count, locomotor time 20.10.10.60.50.2-0.3-0.50.2-0.20.20.2-0.40.40.30.8-0.80.3-0.30.40.30.3-0.2-0.3-0.30.3-0.2-0.0
Light reinforcement 10.00.10.8-0.40.00.20.3-0.00.1-0.1-0.10.3-0.3-0.2-0.10.1-0.20.2-0.2-0.3-0.1-0.0-0.2-0.20.10.40.9
Light reinforcement 20.40.61.10.80.8-0.7-0.70.7-0.70.70.7-0.70.70.70.6-0.60.7-0.80.80.80.8-0.9-0.9-0.90.9-0.61.1
Bone: marrow area0.00.00.10.1-0.00.10.0-0.10.0-0.0-0.0-0.10.10.1-0.00.00.3-0.30.30.20.1-0.0-0.0-0.10.1-0.20.0
Bone: maximum diameter0.20.30.5-0.2-0.30.60.5-0.70.7-0.7-0.70.5-0.5-0.6-0.60.6-0.50.5-0.5-0.4-0.60.60.60.5-0.50.2-0.3
Bone: maximum force0.40.81.0-0.8-0.90.90.9-1.01.0-1.0-1.00.8-0.7-0.8-1.01.0-0.60.6-0.6-0.8-0.91.01.00.9-0.81.0-0.8
Bone: maximum moment0.61.01.3-1.0-1.11.01.0-1.11.1-1.1-1.10.9-0.9-0.9-1.11.1-0.80.8-0.8-1.0-1.01.11.11.0-1.01.1-0.9
Mean time between licks in bursts0.81.12.1-0.8-0.41.11.1-1.11.1-1.1-1.10.9-0.9-1.0-1.21.2-1.01.0-0.8-0.6-1.11.21.41.3-1.20.2-1.4
Mean num. licks in bursts0.20.21.1-0.6-0.50.10.3-0.20.2-0.2-0.20.3-0.3-0.2-0.30.3-0.30.3-0.3-0.6-0.40.40.50.6-0.60.8-1.0
Cd content in liver0.50.64.20.70.9-0.3-0.30.3-0.30.30.3-0.50.50.40.4-0.40.6-0.60.61.00.6-0.6-0.8-0.91.0-1.32.0
Co content in liver0.00.10.60.10.30.10.1-0.0-0.00.00.0-0.00.00.0-0.00.00.00.00.10.30.1-0.0-0.1-0.20.2-0.60.7
Cu content in liver11.413.915.03.83.7-3.8-3.73.7-3.73.73.7-3.83.83.83.8-3.83.9-3.83.93.93.7-3.6-3.6-3.63.7-3.63.2
Fe content in liver2.42.94.01.82.0-1.6-1.51.5-1.61.61.6-1.81.81.81.7-1.71.9-2.01.91.81.7-1.6-1.5-1.61.6-1.51.4
K content in liver1.11.01.61.31.2-1.1-1.00.9-0.80.80.8-1.11.21.11.2-1.21.3-1.21.21.20.9-0.8-0.6-0.60.7-1.1-0.3
Mg content in liver3.63.76.32.52.2-2.0-2.01.6-1.51.51.5-2.12.22.02.1-2.12.3-2.22.32.21.9-1.7-1.5-1.61.7-1.90.5
Mn content in liver3.33.84.61.91.9-2.0-2.02.0-1.91.91.9-2.02.02.01.9-1.92.0-2.01.91.92.0-2.1-2.0-2.01.9-1.71.4
Na content in liver0.60.61.00.90.8-0.9-0.90.7-0.60.60.6-0.90.90.91.0-1.01.0-1.01.00.70.8-0.7-0.6-0.60.6-0.4-0.1
Rb content in liver0.30.41.10.10.5-0.6-0.51.0-1.01.01.0-0.50.50.60.4-0.40.5-0.50.50.60.5-0.5-0.5-0.50.6-0.61.0
Se content in liver0.10.10.40.10.10.20.3-0.60.6-0.6-0.60.2-0.2-0.3-0.30.3-0.10.1-0.10.0-0.20.20.20.1-0.1-0.20.1
Sr content in liver0.50.50.80.90.7-0.7-0.70.5-0.40.40.4-0.70.80.70.8-0.80.8-0.90.80.90.7-0.7-0.5-0.50.4-0.9-0.5
Zn content in liver0.50.51.11.01.0-0.5-0.50.3-0.20.20.2-0.70.70.60.7-0.70.9-0.90.91.00.7-0.5-0.6-0.80.9-1.00.8
Bone: minimum diameter0.00.00.60.2-0.00.0-0.0-0.20.0-0.0-0.0-0.00.10.1-0.00.00.1-0.20.20.1-0.10.20.30.3-0.20.0-0.8
Time in familiar zone, hab. session 10.30.31.30.70.7-0.2-0.20.1-0.10.10.1-0.40.40.30.4-0.40.5-0.40.50.70.5-0.5-0.6-0.60.7-1.11.1
Time in novel zone, hab. session 13.13.16.7-2.0-2.21.41.4-1.31.3-1.3-1.31.7-1.7-1.6-1.51.5-1.81.8-1.8-2.2-1.71.71.71.8-1.92.6-2.0
Total zone transitions, hab. session 16.89.510.33.23.1-3.2-3.13.1-3.13.13.1-3.13.13.13.1-3.13.0-3.13.03.13.1-3.1-3.1-3.13.1-2.92.8
Total locomotion distance, hab. session 14.26.06.92.62.3-2.6-2.62.4-2.42.42.4-2.52.52.52.6-2.62.4-2.42.42.32.5-2.5-2.5-2.52.5-2.02.4
Locomotion velocity, hab. session 15.67.99.23.02.9-2.8-2.82.7-2.72.72.7-2.92.92.92.8-2.82.9-2.92.92.82.9-2.8-2.8-2.82.9-2.52.6
Time in familiar zone, hab. session 21.31.42.0-1.4-1.21.21.2-1.11.1-1.1-1.11.3-1.3-1.2-1.31.3-1.41.4-1.3-1.2-1.21.21.01.1-1.10.8-0.4
Time in novel zone, hab. session 20.20.20.40.60.4-0.5-0.40.3-0.30.30.3-0.50.50.50.5-0.50.6-0.60.50.40.5-0.5-0.4-0.50.50.00.2
Total zone transitions, hab. session 24.96.47.42.52.6-2.5-2.52.5-2.52.52.5-2.52.52.52.3-2.32.5-2.62.52.72.5-2.6-2.5-2.52.5-2.62.7
Total locomotion distance, hab. session 21.31.72.11.41.4-1.3-1.31.3-1.31.31.3-1.41.41.41.2-1.21.3-1.41.41.41.3-1.2-1.2-1.31.3-1.11.4
Locomotion velocity, hab. session 21.52.02.41.51.4-1.4-1.51.4-1.41.41.4-1.51.51.51.4-1.41.5-1.51.51.41.4-1.3-1.3-1.31.4-1.11.3
Novel to familiar place preference ratio0.30.30.60.6-0.1-0.5-0.60.3-0.30.30.3-0.60.60.50.7-0.70.7-0.70.60.30.6-0.5-0.7-0.70.80.10.7
Novelty place preference0.20.20.40.5-0.3-0.4-0.50.2-0.20.20.2-0.40.40.40.6-0.60.5-0.50.50.10.5-0.4-0.6-0.60.70.30.6
Time in novel zone, NPP test0.10.10.30.3-0.4-0.3-0.40.1-0.10.10.1-0.20.20.20.5-0.50.3-0.30.2-0.10.3-0.3-0.5-0.50.50.40.6
Total zone transitions, NPP test6.28.911.23.13.3-2.9-2.92.9-2.92.92.9-3.02.93.02.7-2.72.8-3.03.03.33.0-3.1-3.0-3.03.0-3.03.1
Total locomotion distance, NPP test2.43.34.22.02.0-1.7-1.71.6-1.61.61.6-1.91.91.81.7-1.71.8-2.02.02.01.8-1.8-1.8-1.91.9-1.52.0
Locomotion velocity, NPP test2.84.05.02.22.2-1.9-2.01.8-1.81.81.8-2.12.12.11.9-1.92.1-2.22.22.22.0-2.0-1.9-2.02.0-1.71.8
Intraocular pressure1.31.82.71.61.3-1.4-1.41.3-1.31.31.3-1.41.41.31.2-1.21.4-1.41.31.41.3-1.3-1.3-1.31.3-1.41.1
Delta distance traveled before/after self-admin3.33.64.6-2.1-2.11.91.9-1.81.7-1.7-1.71.9-1.9-1.8-1.91.9-1.91.9-1.8-2.1-1.91.81.71.8-1.82.2-1.9
Delta ambulatory time before/after self-admin3.33.64.9-2.2-2.01.91.9-1.81.7-1.7-1.71.9-1.9-1.8-1.91.9-1.91.9-1.8-2.1-1.91.91.81.8-1.82.2-2.0
Parametrial fat weight0.30.51.10.80.6-0.6-0.70.6-0.60.60.6-0.70.70.60.8-0.80.9-0.70.70.80.7-0.6-0.8-0.80.9-1.00.9
Pavlov. Cond. lever latency1.72.24.7-1.5-1.61.41.3-1.31.3-1.3-1.31.4-1.3-1.3-1.31.3-1.21.2-1.4-1.6-1.41.51.71.7-1.71.8-2.2
Pavlov. Cond. magazine entry latency0.20.31.50.40.1-0.5-0.50.5-0.50.50.5-0.30.30.30.5-0.50.2-0.10.20.30.5-0.5-0.7-0.70.7-0.61.2
Pavlov. Cond. change in total contacts4.14.46.72.12.0-2.1-2.02.0-2.02.02.0-2.02.02.02.0-2.02.0-1.91.92.02.1-2.1-2.3-2.32.3-2.22.6
Pavlov. Cond. index score1.11.44.31.11.0-1.1-1.11.1-1.11.11.1-1.01.01.01.1-1.10.9-0.91.01.01.2-1.2-1.5-1.51.5-1.32.1
Pavlov. Cond. latency score1.11.44.01.11.0-1.1-1.11.1-1.11.11.1-1.01.01.11.1-1.11.0-0.91.01.01.2-1.2-1.5-1.51.5-1.22.0
Pavlov. Cond. lever contacts2.93.46.21.82.1-1.6-1.61.7-1.61.61.6-1.71.71.71.6-1.61.7-1.71.82.01.8-1.9-2.0-2.12.1-2.22.5
Pavlov. Cond. magazine entry number0.70.92.5-1.0-0.61.01.0-0.80.8-0.8-0.80.8-0.8-0.8-0.90.9-0.70.7-0.8-0.8-0.90.91.11.1-1.21.0-1.6
Pavlov. Cond. intertrial magazine entries1.41.73.31.31.8-1.2-1.21.2-1.31.31.3-1.41.41.41.3-1.31.5-1.61.51.51.3-1.2-1.0-1.11.1-1.20.6
Pavlov. Cond. lever-magazine prob. diff.0.91.23.90.90.9-1.0-1.01.0-1.01.01.0-0.90.90.91.0-1.00.8-0.70.80.91.1-1.1-1.4-1.41.4-1.22.0
Pavlov. Cond. response bias0.91.13.61.10.9-1.0-1.00.9-0.90.90.9-0.90.90.90.9-0.90.8-0.70.81.01.0-1.1-1.3-1.31.3-1.41.9
Pavlov. Cond. lever latency2.23.04.92.22.0-1.7-1.81.5-1.61.61.6-1.71.71.61.7-1.71.5-1.51.61.71.7-1.6-1.7-1.81.9-2.01.9
Pavlov. Cond. magazine entry latency0.30.30.90.20.5-0.6-0.50.8-0.70.70.7-0.60.60.70.5-0.50.6-0.70.70.50.5-0.5-0.2-0.20.0-0.1-0.9
Pavlov. Cond. change in total contacts0.70.92.0-1.3-1.21.01.0-0.80.8-0.8-0.80.9-0.9-0.9-0.90.9-0.80.8-0.9-0.8-0.90.81.01.0-1.10.8-1.4
Pavlov. Cond. index score0.60.82.4-1.3-1.00.80.9-0.60.7-0.7-0.70.8-0.8-0.7-0.80.8-0.70.6-0.7-0.9-0.80.81.01.0-1.21.2-1.5
Pavlov. Cond. latency score0.40.52.2-1.0-0.70.60.6-0.40.4-0.4-0.40.6-0.5-0.5-0.60.6-0.50.4-0.5-0.7-0.60.50.80.8-0.90.9-1.5
Pavlov. Cond. lever contacts1.52.03.5-1.9-1.71.51.5-1.31.3-1.3-1.31.4-1.4-1.4-1.41.4-1.21.2-1.4-1.4-1.41.31.41.4-1.51.5-1.5
Pavlov. Cond. magazine entry number0.20.32.90.70.4-0.2-0.30.0-0.10.10.1-0.20.20.10.3-0.30.0-0.00.00.40.3-0.3-0.7-0.70.8-0.81.7
Pavlov. Cond. intertrial magazine entries2.02.64.02.01.7-1.6-1.71.4-1.51.51.5-1.51.51.51.7-1.71.3-1.41.41.71.6-1.6-1.7-1.71.8-1.82.0
Pavlov. Cond. lever-magazine prob. diff.0.81.02.7-1.4-1.11.01.0-0.70.8-0.8-0.80.9-0.9-0.9-1.01.0-0.80.7-0.8-1.0-1.00.91.11.1-1.31.2-1.6
Pavlov. Cond. response bias1.11.42.7-1.7-1.31.21.3-1.01.1-1.1-1.11.1-1.1-1.1-1.21.2-1.00.9-1.0-1.1-1.21.11.31.3-1.41.3-1.5
Time in closed arm before self-admin2.83.24.1-1.3-2.01.61.5-1.91.9-1.9-1.91.7-1.8-1.8-1.61.6-1.91.8-1.8-1.8-1.82.01.91.9-1.81.8-1.7
Time in closed arm after self-admin3.23.37.6-1.3-1.91.61.5-1.91.9-1.9-1.91.6-1.6-1.6-1.41.4-1.61.5-1.5-1.9-1.82.02.01.9-1.82.3-2.8
Time in open arm before self-admin0.60.61.30.71.1-0.8-0.70.8-0.60.60.6-0.80.80.80.6-0.60.7-0.70.90.90.8-0.8-0.8-0.80.8-1.00.8
Time in open arm after self-admin0.40.41.30.70.8-0.6-0.50.5-0.60.60.6-0.60.60.50.3-0.30.6-0.60.50.80.6-0.8-0.7-0.70.6-1.11.2
Bone: periosteal estimation0.20.30.7-0.3-0.50.60.6-0.80.7-0.7-0.70.5-0.5-0.5-0.70.7-0.30.3-0.3-0.3-0.60.70.60.6-0.50.3-0.5
Bone: periosteal perimeter0.81.31.9-0.8-0.91.11.1-1.41.3-1.3-1.31.1-1.1-1.2-1.21.2-1.11.1-1.1-1.1-1.21.21.21.1-1.11.0-1.1
Bone: post-yield work0.70.91.3-1.0-1.11.01.0-1.00.8-0.8-0.80.9-0.9-0.9-1.11.1-0.90.9-0.9-0.9-1.01.01.11.1-1.10.8-1.2
Progressive ratio test 1 active lever presses1.21.31.70.91.0-1.0-1.01.2-1.01.01.0-1.21.21.21.2-1.21.2-1.21.31.11.1-1.1-1.1-1.21.2-1.11.0
Progressive ratio test 1 breakpoint1.31.41.90.91.1-1.1-1.11.2-1.11.11.1-1.31.31.21.3-1.31.3-1.21.41.21.2-1.1-1.1-1.21.2-1.10.9
Progressive ratio test 1 inactive lever presses0.30.30.6-0.8-0.70.60.7-0.50.6-0.6-0.60.7-0.7-0.7-0.70.7-0.60.7-0.7-0.5-0.50.50.30.3-0.30.20.2
Progressive ratio test 2 active lever presses1.81.92.61.61.5-1.3-1.41.3-1.01.01.0-1.41.41.31.6-1.61.4-1.51.61.61.3-1.1-1.3-1.31.5-1.61.3
Progressive ratio test 2 breakpoint1.01.21.81.31.2-1.0-1.11.0-0.70.70.7-1.11.11.01.3-1.31.1-1.11.21.21.0-0.8-1.0-1.11.2-1.31.1
Progressive ratio test 2 inactive lever presses0.10.10.20.30.4-0.1-0.20.20.0-0.0-0.0-0.30.30.30.4-0.40.4-0.40.50.40.2-0.1-0.2-0.30.4-0.50.4
Incentive Sensitization - Responses0.50.51.41.20.8-0.6-0.70.4-0.10.10.1-0.70.70.50.9-0.90.8-0.80.70.90.6-0.4-0.5-0.70.9-1.10.9
Incentive Sensitization - Breakpoint0.30.30.90.90.5-0.4-0.50.20.2-0.2-0.2-0.40.40.20.6-0.60.5-0.50.40.70.4-0.2-0.4-0.50.7-0.90.8
Sum of active levers in priming session hrs 5-65.14.96.22.12.0-2.4-2.42.5-2.52.52.5-2.32.32.32.2-2.22.3-2.22.22.02.3-2.3-2.2-2.12.0-1.81.4
Progressive ratio0.20.21.1-0.80.10.91.0-0.60.7-0.7-0.70.2-0.2-0.2-0.20.2-0.1-0.10.30.3-0.20.10.1-0.10.0-0.50.9
Food seeking constrained by brief footshock0.10.10.9-1.0-0.40.40.6-0.0-0.00.00.00.2-0.3-0.1-0.40.4-0.10.2-0.1-0.3-0.20.10.00.0-0.10.10.3
Seeking ratio, punishment vs. effort0.50.61.50.90.3-1.2-1.21.1-1.21.21.2-0.70.60.70.6-0.60.7-0.40.20.20.7-0.6-0.6-0.50.5-0.0-0.2
Retroperitoneal fat weight0.20.51.0-0.3-0.50.70.6-0.91.0-1.0-1.00.7-0.7-0.8-0.60.6-0.70.7-0.7-0.6-0.70.80.70.7-0.60.4-0.1
Reaction time number correct1.42.02.7-1.3-1.31.41.4-1.41.5-1.5-1.51.3-1.3-1.3-1.61.6-1.41.4-1.2-1.3-1.51.51.61.5-1.61.2-1.6
Reaction time mean minus median1.92.53.91.41.3-1.6-1.61.6-1.51.51.5-1.61.71.62.0-2.02.0-1.81.61.51.7-1.7-1.6-1.51.5-1.10.7
Reaction time mean minus median AUC3.03.85.51.81.7-2.1-2.02.0-1.81.81.8-2.02.12.02.2-2.22.4-2.22.01.92.1-2.0-1.9-1.91.9-1.61.0
Reaction time num false alarms0.81.01.70.71.0-1.1-1.01.3-1.31.31.3-0.90.81.01.0-1.00.5-0.70.80.91.0-1.0-1.1-1.01.0-1.01.0
Reaction time num false alarms AUC0.81.11.80.81.1-1.1-1.11.3-1.31.31.3-0.90.91.01.0-1.00.6-0.80.81.01.0-1.1-1.1-1.11.0-1.21.1
Reaction time trials correct on left1.42.02.7-1.3-1.31.41.4-1.41.5-1.5-1.51.3-1.3-1.3-1.61.6-1.41.4-1.2-1.3-1.51.51.61.5-1.61.2-1.6
Reaction time trials on left1.31.92.6-1.2-1.21.31.3-1.31.4-1.4-1.41.3-1.3-1.3-1.61.6-1.41.4-1.2-1.2-1.41.41.51.5-1.51.2-1.6
Reaction time mean1.21.62.91.40.9-1.5-1.51.3-1.31.31.3-1.31.41.31.7-1.71.5-1.41.21.11.3-1.2-1.2-1.11.2-0.90.2
Reaction time mean AUC1.52.03.41.50.9-1.6-1.61.4-1.41.41.4-1.41.51.41.8-1.81.7-1.51.41.11.5-1.4-1.3-1.31.3-0.90.3
Median of all reaction times0.50.71.31.00.3-1.0-1.00.8-0.90.90.9-0.80.90.81.1-1.10.9-0.80.70.60.9-0.7-0.7-0.70.8-0.50.0
Reaction time omissions1.11.62.31.01.2-1.2-1.01.3-1.31.31.3-1.21.31.31.1-1.11.4-1.31.31.41.3-1.3-1.3-1.31.2-1.50.9
Reaction time false alarm rate1.62.32.91.21.5-1.5-1.51.7-1.71.71.7-1.41.31.41.6-1.61.1-1.21.21.51.5-1.6-1.6-1.61.6-1.61.7
Reaction time premature initiation rate0.20.20.60.50.8-0.4-0.40.4-0.50.50.5-0.50.50.50.3-0.30.4-0.50.50.60.5-0.6-0.6-0.50.5-0.40.6
Reaction time premature initiations0.00.10.2-0.10.10.20.2-0.20.2-0.2-0.20.2-0.2-0.1-0.50.5-0.30.1-0.1-0.1-0.20.10.20.2-0.30.3-0.3
Std. dev. reaction times1.92.63.91.61.3-1.8-1.81.8-1.61.61.6-1.71.71.72.0-2.01.9-1.71.61.51.7-1.6-1.5-1.51.4-1.20.4
Reaction time trials completed1.31.92.6-1.2-1.21.31.3-1.31.4-1.4-1.41.3-1.3-1.3-1.61.6-1.41.4-1.2-1.2-1.41.41.51.5-1.51.2-1.6
Reaction time trials AUC1.42.02.5-1.3-1.31.31.3-1.41.4-1.4-1.41.3-1.3-1.3-1.61.6-1.41.4-1.2-1.3-1.51.41.51.5-1.51.3-1.6
Run reversals in cocaine runway, females0.10.10.40.30.0-0.5-0.60.5-0.50.50.5-0.20.20.30.2-0.20.0-0.10.00.00.2-0.2-0.1-0.00.00.2-0.6
Run reversals in cocaine runway, males0.90.91.9-0.80.11.41.4-1.31.4-1.4-1.40.9-0.9-1.0-0.90.9-0.70.6-0.6-0.2-0.90.90.90.7-0.6-0.10.3
Latency to leave start box in cocaine runway5.45.88.4-2.3-2.82.42.4-2.82.7-2.7-2.72.3-2.2-2.3-1.81.8-1.82.0-2.1-2.6-2.32.52.52.4-2.32.9-2.8
Latency to leave start box in cocaine runway, F8.89.613.9-3.0-3.13.23.1-3.33.2-3.2-3.23.0-2.9-3.0-2.82.8-2.62.7-2.8-3.2-3.03.13.23.1-3.13.5-3.7
Latency to leave start box in cocaine runway, M0.10.10.40.2-0.60.0-0.0-0.40.4-0.4-0.4-0.00.1-0.00.5-0.50.4-0.20.2-0.10.10.1-0.0-0.00.20.20.4
Std. dev. time between licks in bursts0.70.91.4-1.1-0.70.91.1-0.90.9-0.9-0.91.0-1.0-0.9-1.21.2-1.01.0-0.9-0.8-1.00.91.01.0-1.00.6-0.6
Total sessions with >9 infusions0.70.81.30.81.1-0.8-0.80.8-1.11.11.1-0.90.91.00.9-0.90.9-0.90.91.00.8-0.9-0.7-0.70.6-1.00.5
Short access day 1 total inactive lever presses0.10.10.20.10.2-0.3-0.30.5-0.30.30.3-0.20.20.20.2-0.20.4-0.30.20.30.3-0.4-0.4-0.40.3-0.20.5
Short access day 10 total inactive lever presses0.30.30.5-0.6-0.40.60.6-0.60.7-0.7-0.70.6-0.6-0.7-0.60.6-0.40.5-0.7-0.5-0.50.60.50.4-0.30.3-0.3
Short access day 1 total infusions0.00.00.0-0.10.20.10.10.0-0.20.20.2-0.00.00.00.0-0.00.1-0.00.00.10.1-0.2-0.00.0-0.1-0.1-0.1
Short access day 10 total infusions0.20.20.70.30.4-0.3-0.30.3-0.30.30.3-0.50.50.60.6-0.60.6-0.60.80.30.3-0.2-0.1-0.10.2-0.0-0.8
Short access total infusions0.00.00.4-0.20.10.10.1-0.0-0.10.10.1-0.10.10.10.1-0.10.1-0.10.2-0.0-0.10.00.20.2-0.30.1-0.6
Short access day 1 locomotion0.00.00.0-0.20.10.20.2-0.1-0.20.20.20.0-0.00.0-0.10.10.0-0.10.10.1-0.10.00.10.1-0.2-0.1-0.1
Short access day 10 total locomotion1.11.21.61.11.3-1.1-1.11.1-1.21.21.2-1.21.21.21.1-1.11.2-1.21.21.21.1-1.0-1.0-1.01.0-1.10.3
Short access total locomotion0.20.20.60.30.8-0.3-0.30.4-0.70.70.7-0.50.50.60.3-0.30.4-0.50.60.50.3-0.3-0.2-0.20.2-0.4-0.4
One hour access (0.3 mA shock)1.01.22.11.01.0-1.0-1.01.1-0.90.90.9-1.11.11.11.2-1.21.2-1.11.21.11.0-0.9-1.0-1.01.1-1.31.5
Compulsive drug intake6.36.38.42.42.4-2.7-2.72.9-2.72.72.7-2.52.52.42.5-2.52.5-2.32.12.22.6-2.6-2.5-2.42.4-2.22.6
One hour access (shock baseline)0.70.81.7-0.7-0.81.11.1-1.21.3-1.3-1.30.8-0.8-0.9-0.80.8-0.80.7-0.5-0.5-0.91.00.90.7-0.60.4-0.4
Social response proportion2.02.13.01.61.1-1.7-1.61.5-1.51.51.5-1.41.41.61.5-1.51.3-1.31.51.41.5-1.5-1.5-1.51.4-1.31.3
Social responses0.10.11.2-0.1-0.3-0.00.10.00.0-0.0-0.00.2-0.2-0.1-0.20.2-0.30.3-0.1-0.0-0.0-0.1-0.3-0.20.2-0.41.1
Social time0.20.33.20.10.50.20.4-0.20.2-0.2-0.20.3-0.3-0.3-0.50.5-0.40.4-0.40.4-0.1-0.0-0.3-0.30.4-1.31.8
Soleus weight1.64.87.6-2.5-2.42.02.1-1.92.0-2.0-2.02.2-2.2-2.1-2.12.1-2.22.2-2.2-2.5-2.22.22.22.2-2.22.7-2.1
Bone: stiffness0.00.00.10.2-0.10.00.0-0.30.3-0.3-0.3-0.00.0-0.1-0.10.10.1-0.10.10.1-0.10.20.30.2-0.1-0.0-0.1
Tibialis anterior weight0.10.21.1-0.2-0.4-0.3-0.30.5-0.60.60.6-0.20.20.30.3-0.30.2-0.10.2-0.00.4-0.4-0.6-0.50.50.11.0
Time to tail flick, vehicle, before self-admin1.11.21.90.90.7-1.2-1.21.2-1.31.31.3-1.01.01.01.3-1.31.0-0.80.80.81.1-1.1-1.1-1.01.0-0.91.4
Time to tail flick, vehicle, after self-admin0.70.81.9-0.4-0.70.60.7-1.01.1-1.1-1.10.8-0.8-0.8-0.60.6-0.90.7-0.7-0.9-0.90.90.90.9-0.91.0-1.4
Time to tail flick, test, before self-admin1.01.02.0-0.9-1.30.80.6-0.60.7-0.7-0.71.0-1.0-0.9-0.20.2-1.21.2-1.1-1.3-1.01.01.11.2-1.21.4-1.2
Time to tail flick, test, after self-admin0.80.82.0-1.0-1.40.70.6-0.50.6-0.6-0.60.8-0.8-0.8-0.60.6-0.91.0-0.9-1.3-0.80.90.91.0-1.01.3-1.2
Delta time to tail flick, vehicle, before/after SA3.03.03.9-1.3-1.51.61.6-1.92.0-2.0-2.01.7-1.7-1.7-1.81.8-1.71.6-1.5-1.6-1.71.81.71.7-1.71.7-1.9
Delta time to tail flick, test, before/after SA0.40.30.50.40.3-0.5-0.50.7-0.70.70.7-0.50.50.60.2-0.20.6-0.50.50.50.6-0.7-0.7-0.60.6-0.60.7
Tibia length0.61.72.6-1.2-1.21.21.2-1.31.2-1.2-1.21.2-1.2-1.2-1.41.4-1.11.1-1.1-1.4-1.41.41.61.5-1.51.6-1.4
Ambulatory time before self-admin2.52.64.92.11.7-1.5-1.61.3-1.11.11.1-1.51.51.41.5-1.51.6-1.61.61.91.6-1.5-1.6-1.71.8-2.12.2
Ambulatory time after self-admin0.20.20.5-0.3-0.70.30.4-0.50.7-0.7-0.70.5-0.5-0.5-0.40.4-0.50.5-0.4-0.6-0.50.60.30.3-0.20.5-0.2
Bone: tissue strength0.90.91.4-0.9-0.51.01.0-1.01.0-1.0-1.00.8-0.8-0.9-1.01.0-0.80.8-0.8-0.8-1.01.11.21.1-1.10.6-1.1
Total heroin consumption0.30.41.20.10.4-0.8-0.60.9-0.80.80.8-0.50.50.60.5-0.50.5-0.40.30.20.6-0.7-0.8-0.70.6-0.31.1
Bone: trabecular number0.10.10.7-0.2-0.70.10.1-0.30.3-0.3-0.30.1-0.1-0.1-0.10.10.0-0.00.0-0.4-0.10.20.10.10.00.90.2
Bone: trabecular spacing0.10.10.9-0.20.20.30.3-0.10.2-0.2-0.20.3-0.3-0.3-0.50.5-0.40.3-0.30.2-0.10.0-0.1-0.10.1-0.60.9
Bone: trabecular thickness3.94.78.5-2.0-2.41.91.9-2.12.1-2.1-2.12.0-2.0-2.0-1.91.9-1.91.9-1.9-2.4-2.12.22.42.4-2.42.8-2.9
Bone: trabecular tissue density0.10.11.20.30.6-0.1-0.00.1-0.10.10.1-0.00.0-0.0-0.10.1-0.10.1-0.10.5-0.1-0.00.20.2-0.3-1.1-0.5
Water consumed over 24 hours0.00.10.20.20.4-0.1-0.10.1-0.20.20.2-0.30.30.30.1-0.10.3-0.30.40.30.2-0.2-0.2-0.20.2-0.2-0.1
Number of responses in last shaping day2.12.12.6-1.5-1.31.51.5-1.51.4-1.4-1.41.5-1.5-1.5-1.51.5-1.51.4-1.4-1.3-1.51.61.61.6-1.61.3-1.2