Hub : Genes

Gls

Models

All models for this gene with cis-heritability P-value <0.01 were tested and are shown here. In each tissue, a gene can have zero, one, or multiple RNA phenotypes for each RNA modality. After the heritability statistics, subsequent columns show cross-validation performance (R2 and P-value) of each modeling method. The best-performing method for each models is used for TWAS.

# Tissue Modality RNA phenotype h2 h2 SE h2 P xQTL R2 BLUP R2 ENET R2 LASSO R2 xQTL P BLUP P ENET P LASSO P
1 Brain isoform ratio NM_012569.4 0.04 0.04 1.6e-03 0.02 0.02 0.03 0.01 7.5e-03 8.8e-03 1.7e-03 2.5e-02
2 PL alternative polyA NM_012569.4 0.03 0.03 9.5e-03 0.01 0.01 0.01 0.01 7.1e-03 8.5e-03 6.2e-02 1.5e-02
3 PL alternative polyA XM_039083006.1 0.03 0.02 2.4e-03 0.02 0.01 -0 0.01 4.7e-03 1.1e-02 3.9e-01 3.7e-02
4 Brain isoform ratio NM_001109968.3 0.03 0.03 3.5e-03 0.02 0.02 0.01 0.01 8.0e-03 1.2e-02 9.1e-02 4.0e-02
5 PL intron excision ratio chr9_49389405_49411050 0.03 0.03 9.1e-04 0.02 0.03 0.01 0.02 3.0e-03 7.6e-04 1.4e-02 3.8e-03
6 PL intron excision ratio chr9_49389405_49390302 0.03 0.03 9.4e-04 0.02 0.03 0.01 0.02 2.8e-03 7.7e-04 1.2e-02 2.6e-03
7 Brain isoform ratio XM_039083008.1 0.04 0.03 2.4e-04 0.02 0.04 0.02 0.03 3.1e-03 3.2e-04 2.6e-03 2.0e-03
8 Adipose mRNA stability Gls 0.05 0.04 1.0e-06 0.03 0.04 0.03 0.03 1.9e-04 9.0e-05 1.8e-04 3.5e-04
9 NAcc isoform ratio XM_039083009.1 0.06 0.09 2.0e-03 0.01 0.01 0.01 0.01 6.2e-02 7.6e-03 8.0e-03 1.2e-02
10 PL isoform ratio NM_012569.4 0.04 0.03 1.4e-04 0.03 0.04 0.03 0.03 2.4e-04 8.7e-05 1.5e-04 2.2e-04
11 NAcc isoform ratio NM_001109968.3 0.03 0.03 9.2e-04 0.02 0.02 0.02 0.02 1.6e-03 1.9e-03 4.8e-03 5.3e-03
12 Adipose gene expression Gls 0.28 0.13 4.1e-04 0.01 0.01 0 0.01 1.5e-02 3.0e-02 1.0e-01 2.1e-02
13 NAcc isoform ratio NM_012569.4 0.03 0.04 1.6e-03 0.01 0.02 0.01 0.01 8.0e-03 5.1e-03 3.7e-02 3.4e-02
14 Brain alternative TSS XM_039083009.1 0.03 0.03 3.8e-03 0.02 0.01 0 0.01 2.8e-03 2.6e-02 2.3e-01 1.9e-02
15 Adipose alternative polyA NM_012569.4 0.11 0.12 4.4e-04 0.01 0.01 0.02 0.01 3.2e-02 9.5e-03 4.1e-03 8.8e-03
16 Adipose alternative polyA NM_012569.4 0.28 0.13 1.2e-04 0.01 0.03 0.01 0.01 3.5e-02 5.5e-04 1.4e-02 5.7e-02
17 Adipose isoform ratio XM_039083009.1 0.05 0.07 2.4e-03 0 0 0.01 0 1.0e-01 1.0e-01 6.0e-02 1.5e-01
18 Adipose isoform ratio NM_012569.4 0.28 0.13 8.2e-04 0.01 0.01 0.01 0 6.5e-02 2.0e-02 4.3e-02 9.5e-02
19 Brain alternative polyA NM_012569.4 0.03 0.04 5.9e-03 0.01 0.01 0.02 0 2.5e-02 2.6e-02 7.2e-03 1.2e-01

Trait associations

The numbered columns correspond to the numbered models in the table above. They contain the TWAS Z-score for each trait-model pair. Colors indicate strength of Z-scores: cells with lower negative Z-scores are darker blue, cells with higher positive Z-scores are darker red. Significant associations have white and bolded text.

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Bone: apparent density2.54.27.8-1.5-2.02.02.12.1-2.0-1.9-1.9-2.31.91.81.81.72.0-2.22.62.82.7-0.9
Area under the delay curve0.00.00.10.1-0.00.0-0.2-0.10.10.10.10.2-0.1-0.2-0.2-0.1-0.20.3-0.2-0.1-0.2-0.3
BMI with tail5.919.022.14.44.7-4.7-4.6-4.64.64.64.64.6-4.6-4.5-4.5-4.6-4.54.2-4.1-3.9-3.52.7
BMI without tail1.53.04.91.91.8-1.8-2.1-1.81.81.91.81.8-1.8-1.7-1.7-1.9-2.21.7-1.3-1.3-1.11.0
Body weight0.10.31.7-0.40.2-0.2-0.2-0.40.30.20.20.6-0.3-0.3-0.3-0.10.00.5-1.1-1.3-1.3-0.5
Weight adjusted by age0.40.41.0-1.0-0.90.90.70.6-0.6-0.7-0.7-0.50.70.60.60.80.8-0.4-0.0-0.2-0.3-0.5
Bone surface0.71.31.9-0.8-1.21.21.11.2-1.2-1.1-1.1-1.21.11.01.01.01.1-0.91.31.41.3-0.9
Bone volume2.33.95.3-1.6-2.02.02.22.0-2.0-1.9-1.9-2.11.91.91.91.82.1-1.92.32.32.2-1.2
Breakpoint value in progressive ratio session0.60.61.5-0.9-0.90.90.90.8-0.9-0.9-0.9-0.70.90.80.81.00.9-0.30.30.1-0.1-1.2
Number of licking bursts0.20.20.40.30.5-0.5-0.7-0.40.50.50.50.3-0.5-0.5-0.5-0.6-0.1-0.20.00.30.4-0.2
Context. condit. distance diff. score1.11.34.41.01.3-1.3-0.9-1.21.21.21.21.1-1.2-1.0-1.0-1.2-0.60.7-0.8-0.8-0.42.1
Locomotion velocity, session 10.20.22.00.40.2-0.2-0.0-0.20.20.20.20.3-0.2-0.3-0.3-0.2-0.20.7-0.3-0.5-0.51.4
Locomotion distance, session 10.30.43.50.60.5-0.5-0.2-0.50.40.40.40.5-0.4-0.2-0.2-0.4-0.00.7-0.4-0.8-0.51.9
Locomotion velocity, session 22.12.54.61.91.4-1.4-1.6-1.51.41.41.41.6-1.4-1.6-1.6-1.4-1.72.1-1.6-1.6-1.71.4
Locomotion distance, session 20.50.72.50.90.9-0.9-0.4-0.80.80.70.80.9-0.7-0.6-0.6-0.7-0.61.0-0.8-1.1-0.81.6
Locomotion velocity, session 30.20.22.10.40.5-0.50.2-0.40.40.30.40.3-0.3-0.1-0.1-0.30.10.1-0.3-0.4-0.11.4
Locomotion distance, session 30.40.53.80.70.8-0.8-0.1-0.60.60.70.70.5-0.7-0.5-0.5-0.7-0.30.1-0.3-0.10.12.0
Stereotopy head waving bouts, day 30.70.81.31.00.8-0.8-1.1-0.80.80.80.80.9-0.8-0.8-0.8-0.8-1.01.1-0.9-1.0-1.00.2
Stereotopy head waving duration, day 30.20.20.50.50.2-0.2-0.6-0.30.20.20.20.4-0.2-0.3-0.3-0.2-0.50.7-0.4-0.6-0.6-0.7
Locomotion velocity, session 70.30.32.60.40.2-0.2-0.0-0.20.20.10.20.4-0.1-0.1-0.1-0.0-0.10.9-0.7-0.8-0.91.6
Locomotion distance, session 70.40.52.00.30.3-0.3-0.3-0.50.40.30.30.6-0.3-0.4-0.4-0.2-0.51.2-1.2-1.2-1.40.5
Stereotopy head waving bouts, day 70.10.10.2-0.2-0.40.40.40.4-0.4-0.4-0.4-0.40.40.50.50.40.2-0.20.30.20.20.4
Stereotopy head waving duration, day 70.60.81.1-0.7-0.90.90.91.0-0.9-1.0-0.9-0.91.01.01.00.90.7-0.90.90.80.80.3
Locomotion velocity, session 80.60.76.50.90.7-0.7-0.5-0.60.60.70.70.5-0.7-0.5-0.5-0.7-0.50.4-0.2-0.10.12.6
Locomotion distance, session 81.31.911.71.31.6-1.6-0.8-1.31.41.31.41.3-1.4-1.0-1.0-1.4-0.60.8-0.9-1.0-0.43.4
Degree of sensitization distance0.40.43.0-0.6-0.60.60.10.4-0.4-0.5-0.5-0.10.50.40.40.70.00.5-0.4-0.7-0.9-1.7
Degree of sensitization stereotypy0.20.30.6-0.2-0.50.50.60.5-0.5-0.4-0.4-0.60.40.50.50.40.4-0.60.60.80.70.7
Conditioned locomotion0.20.20.9-1.0-0.10.10.50.2-0.2-0.3-0.2-0.10.20.40.40.30.8-0.5-0.2-0.5-0.2-0.9
Cocaine response after cond. corrected0.20.21.2-0.7-0.10.10.40.0-0.1-0.2-0.20.20.20.10.10.30.30.3-0.7-1.1-1.0-0.7
Cocaine response after cond. not corrected0.91.02.0-1.4-1.01.01.10.9-1.0-1.1-1.1-0.61.11.01.01.31.0-0.20.0-0.5-0.5-1.4
Cocaine response before conditioning0.81.01.3-0.7-1.21.20.91.1-1.1-1.1-1.1-1.11.21.11.11.10.5-0.61.00.80.7-0.6
Saline control response0.20.21.20.40.4-0.4-0.6-0.30.30.40.40.2-0.4-0.4-0.4-0.5-0.5-0.20.20.50.51.1
Bone: connectivity density0.30.51.8-0.3-0.60.60.70.6-0.6-0.5-0.5-0.80.50.30.30.40.7-0.71.11.31.30.5
Bone: cortical apparent density8.010.613.33.03.1-3.1-3.3-3.33.33.23.23.4-3.2-3.5-3.5-3.1-3.33.6-3.6-3.3-3.51.6
Bone: cortical area0.10.10.6-0.4-0.00.00.3-0.00.0-0.1-0.10.20.10.00.00.20.40.3-0.5-0.6-0.7-0.7
Bone: cortical porosity2.42.65.4-1.2-1.41.41.71.6-1.5-1.5-1.5-1.81.41.51.51.31.5-2.12.22.12.3-0.5
Bone: cortical porosity3.33.66.4-1.6-1.61.62.01.9-1.8-1.8-1.8-2.01.81.81.81.61.8-2.42.42.22.5-0.7
Bone: cortical thickness1.52.53.31.41.6-1.6-1.6-1.71.71.61.71.7-1.7-1.7-1.7-1.6-1.51.6-1.8-1.6-1.60.3
Bone: cortical thickness0.00.00.3-0.0-0.10.1-0.10.0-0.0-0.1-0.1-0.00.1-0.0-0.00.10.10.2-0.1-0.0-0.1-0.5
Bone: cortical tissue density7.910.413.13.03.1-3.1-3.3-3.33.33.23.23.4-3.2-3.4-3.4-3.1-3.23.6-3.6-3.2-3.41.6
Condit. Reinf. active minus inactive responses5.05.67.4-2.7-2.52.52.62.4-2.4-2.5-2.5-2.32.52.62.62.62.2-2.12.01.41.5-2.4
Condit. Reinf. active-inactive response ratio2.93.14.4-2.0-1.81.82.01.8-1.8-1.9-1.8-1.61.92.02.01.91.7-1.51.40.90.9-2.1
Condit. Reinf. active responses3.94.86.8-2.6-2.42.42.32.3-2.3-2.4-2.4-2.12.42.42.42.52.1-1.91.61.11.0-1.9
Condit. Reinf. inactive responses0.10.10.3-0.5-0.40.40.20.3-0.3-0.4-0.4-0.10.40.30.30.50.20.1-0.3-0.5-0.60.3
Incentive salience index mean3.64.45.1-2.2-2.22.22.12.1-2.1-2.1-2.2-2.12.12.22.22.11.8-2.02.01.71.7-2.3
Condit. Reinf. lever presses0.60.81.3-0.7-0.90.90.60.9-0.9-0.8-0.8-0.90.80.80.80.80.5-1.01.01.01.0-1.1
Condit. Reinf. active minus inactive responses3.94.89.0-2.5-2.32.32.32.2-2.3-2.3-2.3-2.22.32.12.12.32.0-2.01.71.61.3-3.0
Condit. Reinf. active-inactive response ratio3.23.34.9-1.9-1.91.91.81.9-1.9-1.8-1.8-1.91.81.71.71.81.7-1.91.61.81.5-2.2
Condit. Reinf. active responses1.11.55.2-1.5-1.31.31.31.2-1.2-1.3-1.3-1.11.31.21.21.31.0-0.90.60.50.3-2.3
Condit. Reinf. inactive responses0.00.00.30.10.0-0.00.1-0.00.0-0.0-0.00.10.00.10.10.1-0.00.5-0.3-0.5-0.5-0.2
Condit. Reinf. lever presses0.00.10.1-0.1-0.30.30.20.3-0.3-0.3-0.3-0.30.30.10.10.30.1-0.00.20.30.2-0.1
Condit. Reinf. lever reinforcers received0.91.34.7-1.4-1.21.21.21.1-1.1-1.2-1.2-1.01.21.11.11.30.9-0.70.50.30.1-2.2
Conditioned reinforcement - actives0.60.61.3-0.6-0.80.80.80.8-0.8-0.8-0.8-0.80.80.80.80.80.9-0.60.70.50.5-1.1
Conditioned reinforcement - inactives1.01.11.5-0.8-1.21.21.21.1-1.1-1.1-1.1-1.11.11.11.11.11.2-0.70.90.90.7-1.2
Conditioned locomotion1.72.02.71.41.2-1.2-1.5-1.51.51.41.41.5-1.4-1.5-1.5-1.4-1.51.6-1.6-1.4-1.60.4
Patch foraging indifference point 0 sec3.96.212.63.12.7-2.7-2.5-2.52.62.72.72.3-2.6-2.6-2.6-2.8-2.51.9-1.6-1.1-1.03.6
Patch foraging indifference point AUC0.30.41.01.00.5-0.5-0.8-0.60.60.60.60.4-0.6-0.7-0.7-0.7-0.90.4-0.20.10.00.6
Delay disc. indifference point, 0s delay0.10.10.30.3-0.10.1-0.10.1-0.00.00.0-0.2-0.0-0.1-0.1-0.1-0.2-0.10.40.60.5-0.4
Delay disc. indifference point, 16s delay0.30.40.8-0.6-0.80.80.60.6-0.6-0.6-0.6-0.60.60.60.60.60.6-0.30.40.40.2-0.9
Delay disc. indifference point, 2s delay0.00.00.10.1-0.00.0-0.3-0.10.10.10.10.0-0.1-0.2-0.2-0.2-0.2-0.00.20.30.30.1
Delay disc. indifference point, 24s delay0.10.10.20.10.2-0.2-0.3-0.40.30.30.30.4-0.3-0.3-0.3-0.3-0.30.3-0.4-0.3-0.40.1
Delay disc. indifference point, 4s delay0.50.50.80.50.6-0.6-0.9-0.80.80.80.80.7-0.8-0.9-0.9-0.7-0.80.5-0.7-0.5-0.60.9
Delay disc. indifference point, 8s delay0.30.31.2-0.6-0.70.70.50.5-0.5-0.5-0.5-0.40.50.50.50.60.5-0.10.20.1-0.0-1.1
Indifference point function ln k0.81.11.41.11.1-1.1-1.1-1.11.11.21.11.0-1.2-1.1-1.1-1.2-1.10.8-0.8-0.6-0.50.7
Indifference point function log k0.81.11.41.11.1-1.1-1.1-1.11.11.21.11.0-1.2-1.1-1.1-1.2-1.10.8-0.8-0.6-0.50.7
Patch foraging total patch changes 0 sec3.96.213.43.22.7-2.7-2.5-2.52.52.72.62.2-2.6-2.6-2.6-2.8-2.51.8-1.5-1.0-0.83.7
Patch foraging total patch changes 12 sec0.60.82.21.41.0-1.0-0.7-0.80.90.90.90.7-0.9-1.0-1.0-1.0-0.80.5-0.4-0.2-0.11.5
Patch foraging total patch changes 18 sec2.12.76.72.41.7-1.7-1.6-1.61.61.71.71.4-1.7-1.7-1.7-1.9-1.61.3-0.8-0.4-0.32.6
Patch foraging total patch changes 24 sec1.11.43.92.01.4-1.4-1.1-1.11.11.21.20.9-1.2-1.0-1.0-1.4-1.10.8-0.4-0.20.01.7
Patch foraging total patch changes 6 sec3.65.49.42.92.5-2.5-2.5-2.32.42.52.52.1-2.5-2.5-2.5-2.6-2.31.8-1.5-0.9-0.83.1
Patch foraging time to switch 0 sec1.11.64.1-1.5-1.31.31.61.3-1.3-1.3-1.3-1.21.31.31.31.42.0-1.00.90.70.7-1.1
Patch foraging water rate 0 sec0.81.42.31.41.2-1.2-1.4-1.21.21.21.21.2-1.2-1.1-1.1-1.2-1.51.1-1.0-1.0-0.91.0
Patch foraging water rate 12 sec0.30.40.80.90.8-0.8-0.8-0.70.70.70.70.6-0.7-0.5-0.5-0.8-0.80.5-0.3-0.3-0.10.5
Patch foraging water rate 18 sec0.00.00.3-0.10.2-0.2-0.1-0.20.20.10.20.1-0.2-0.1-0.1-0.20.1-0.3-0.0-0.10.10.6
Patch foraging water rate 24 sec0.10.10.4-0.4-0.20.20.00.1-0.1-0.2-0.20.10.20.30.30.30.2-0.0-0.2-0.6-0.50.3
Patch foraging water rate 6 sec1.01.42.11.31.4-1.4-1.3-1.31.31.31.31.2-1.3-1.1-1.1-1.4-1.20.7-0.7-0.7-0.41.4
Seeking ratio, delayed vs. immediate footshock2.52.93.2-1.8-1.81.81.51.8-1.8-1.8-1.8-1.81.81.81.71.81.6-1.61.61.51.4-1.6
Distance traveled before self-admin6.46.88.2-2.9-2.82.82.72.7-2.7-2.7-2.7-2.72.72.62.62.72.7-2.62.42.32.1-1.8
Distance traveled after self-admin1.71.93.2-1.8-1.31.31.51.5-1.5-1.5-1.5-1.31.51.41.41.61.6-1.31.00.70.7-0.8
Extensor digitorum longus weight4.316.829.63.54.0-4.0-3.5-4.14.13.83.94.5-3.8-3.7-3.7-3.5-3.34.8-5.2-5.4-5.32.5
Bone: elastic displacement0.20.21.10.1-0.00.0-0.30.1-0.00.00.0-0.3-0.0-0.0-0.0-0.2-0.2-0.70.71.01.0-0.8
Bone: elastic work1.62.14.1-1.4-1.51.51.01.5-1.5-1.4-1.4-1.51.41.31.31.41.2-1.41.61.41.4-2.0
Bone: endosteal estimation4.29.211.4-3.2-3.13.13.43.2-3.2-3.2-3.2-3.03.23.33.33.33.4-2.62.72.12.1-2.3
Bone: endosteal perimeter1.73.55.0-2.1-2.02.02.22.0-2.0-2.0-2.0-1.82.02.12.12.12.2-1.41.30.90.9-1.8
Epididymis fat weight0.30.61.6-1.3-0.90.90.60.8-0.8-0.9-0.9-0.60.90.80.81.10.7-0.40.1-0.3-0.3-0.5
Delta time in closed arm before/after self-admin0.90.91.21.01.0-1.0-0.8-1.01.01.01.01.0-1.0-1.0-1.0-1.0-0.91.1-1.0-0.9-0.90.2
Delta time in open arm before/after self-admin5.04.86.9-2.1-2.12.12.32.2-2.2-2.1-2.1-2.32.12.22.22.02.4-2.62.42.22.4-1.3
Diff in mean of infusions in LGA sessions1.31.51.9-1.2-1.41.41.21.3-1.3-1.3-1.3-1.31.31.11.11.31.2-1.01.01.10.8-1.3
Delay discount exponential model param0.00.00.1-0.1-0.00.00.20.2-0.2-0.2-0.2-0.20.20.20.20.20.2-0.30.20.10.20.0
Extinction: sum of active levers before priming1.91.92.6-1.6-1.41.41.51.4-1.5-1.5-1.5-1.31.51.51.51.61.5-1.21.00.60.6-1.3
Active lever presses in extinction session 60.30.30.5-0.7-0.60.60.60.6-0.6-0.6-0.6-0.60.60.60.60.60.5-0.60.50.50.4-0.3
Bone: final force0.81.42.4-1.6-1.21.21.41.1-1.2-1.3-1.2-1.01.31.31.31.41.5-0.90.50.10.1-1.2
Bone: final moment0.40.71.3-1.1-0.80.81.00.8-0.8-0.9-0.9-0.60.91.01.01.01.1-0.60.3-0.1-0.0-0.9
Food consumed during 24 hour testing period0.60.81.3-1.0-0.80.80.90.9-0.9-0.9-0.9-0.90.91.01.00.91.1-0.90.70.60.60.3
Glucose0.50.82.80.71.1-1.1-0.4-0.90.90.91.00.8-1.0-0.8-0.8-1.0-0.30.3-0.7-0.5-0.31.7
Heart weight0.60.81.3-1.0-0.90.90.90.9-0.9-0.9-0.9-0.90.91.01.00.91.1-1.21.00.80.9-0.6
Delay discount hyperbolic model param0.10.10.2-0.2-0.20.20.40.3-0.3-0.3-0.3-0.30.30.40.40.30.4-0.40.30.20.3-0.1
Intermittent access intake day 1-15 change1.01.01.81.31.1-1.1-0.9-1.01.01.01.01.0-1.0-1.0-1.0-1.0-0.91.0-0.9-0.8-0.70.4
Intermittent access intake escalation0.40.40.90.90.7-0.7-0.5-0.70.70.60.60.7-0.6-0.6-0.6-0.6-0.60.8-0.7-0.8-0.7-0.1
Intermittent access intake escalation 20.10.10.30.50.3-0.3-0.1-0.30.30.30.30.3-0.2-0.2-0.2-0.3-0.10.4-0.2-0.3-0.2-0.2
Intermitt. access day 1 inactive lever presses0.10.10.40.40.3-0.3-0.1-0.20.20.30.20.1-0.3-0.3-0.3-0.3-0.00.00.00.20.20.6
Intermitt. access day 15 inactive lever presses1.01.11.2-1.1-1.11.11.11.1-1.1-1.1-1.1-1.11.11.11.11.11.1-1.11.00.90.9-0.8
Intermitt. access escalation Index1.11.02.20.51.0-1.0-0.9-1.00.90.90.91.1-0.9-0.9-0.9-0.8-0.80.8-1.2-1.4-1.21.5
Intermittent access day 1 total infusions0.30.41.0-0.6-0.80.80.40.6-0.6-0.5-0.5-0.70.50.30.30.50.4-0.60.71.00.7-0.9
Intermittent access day 15 total infusions0.20.20.40.60.3-0.3-0.5-0.40.50.50.50.4-0.5-0.6-0.6-0.5-0.50.5-0.3-0.0-0.2-0.4
Intermittent access terminal intake (last 3 days)0.50.50.80.90.6-0.6-0.8-0.80.80.80.80.7-0.8-0.9-0.9-0.9-0.80.7-0.5-0.1-0.3-0.0
Intermittent access total infusions0.10.10.5-0.1-0.30.3-0.10.1-0.00.0-0.0-0.2-0.0-0.2-0.2-0.1-0.1-0.20.30.70.4-0.4
Intermittent access day 1 locomotion0.00.00.4-0.1-0.30.3-0.00.1-0.1-0.0-0.0-0.10.0-0.1-0.10.00.0-0.00.00.30.1-0.7
Intermittent access day 15 total locomotion0.00.00.4-0.0-0.40.40.10.1-0.1-0.1-0.1-0.10.20.00.00.20.10.1-0.1-0.0-0.2-0.6
Intermittent access total locomotion0.10.20.40.40.2-0.2-0.5-0.40.40.40.40.4-0.4-0.6-0.6-0.4-0.40.4-0.4-0.1-0.4-0.1
Intermittent access standard deviation0.20.20.80.90.5-0.5-0.4-0.50.50.50.50.4-0.5-0.6-0.6-0.6-0.50.5-0.4-0.2-0.2-0.1
Left kidney weight0.00.10.3-0.5-0.30.30.30.2-0.3-0.3-0.3-0.10.30.20.20.40.5-0.1-0.3-0.5-0.50.3
Right kidney weight0.10.41.70.30.4-0.4-0.6-0.40.40.30.30.7-0.3-0.4-0.4-0.2-0.40.8-1.0-1.3-1.30.2
Cocaine induced anxiety4.35.08.41.82.1-2.1-2.2-2.22.22.12.12.4-2.1-2.2-2.2-1.9-2.22.6-2.8-2.8-2.90.8
Post-drug Anxiety2.12.34.81.01.4-1.4-1.4-1.51.51.41.41.7-1.4-1.4-1.4-1.2-1.41.7-2.0-2.2-2.10.6
Baseline Anxiety2.72.93.9-1.6-1.71.71.71.7-1.7-1.7-1.7-1.81.71.71.71.61.7-2.02.01.91.9-0.5
Tail length4.012.215.6-3.9-3.93.93.53.7-3.7-3.8-3.8-3.53.83.83.83.83.5-3.03.02.32.2-2.8
Length with tail4.014.621.1-4.6-4.34.34.04.0-4.1-4.2-4.2-3.74.24.14.04.34.1-3.22.72.11.8-3.0
Length without tail0.30.71.8-1.3-0.80.81.10.7-0.7-0.9-0.8-0.50.80.70.71.01.3-0.4-0.4-0.6-0.8-0.9
Times rat made contact with spout0.20.21.20.30.2-0.2-0.30.0-0.00.00.1-0.2-0.00.30.3-0.20.0-0.60.80.71.10.6
Lifetime Intake0.10.10.20.1-0.10.1-0.5-0.20.20.30.20.1-0.3-0.4-0.4-0.3-0.40.2-0.10.30.0-0.3
Liver weight, left0.00.00.1-0.3-0.30.3-0.10.3-0.3-0.3-0.3-0.20.30.20.20.30.1-0.10.10.0-0.0-0.1
Liver weight, right0.00.00.2-0.4-0.20.2-0.00.1-0.1-0.1-0.20.00.1-0.1-0.10.20.10.2-0.2-0.3-0.40.1
Locomotor activity0.00.10.20.20.3-0.3-0.4-0.20.20.20.20.2-0.3-0.2-0.2-0.3-0.40.0-0.1-0.1-0.10.4
Locomotor testing distance0.10.21.00.20.1-0.1-0.20.1-0.10.00.0-0.3-0.00.00.0-0.2-0.1-0.60.70.91.0-0.5
Locomotor testing rearing0.40.60.90.70.9-0.9-0.8-0.90.90.90.90.8-0.9-0.8-0.8-0.9-0.70.4-0.5-0.3-0.2-0.1
Locomotion in novel chamber1.11.42.80.91.0-1.0-1.0-1.21.21.11.11.3-1.1-1.1-1.1-1.0-0.91.5-1.6-1.7-1.70.7
Locomotion in novel chamber post-restriction0.60.71.50.50.7-0.7-0.8-0.80.80.70.70.9-0.8-0.8-0.8-0.7-0.80.9-1.1-1.2-1.20.7
Fecal boli incidents, locomotor time 10.10.10.40.60.3-0.3-0.5-0.30.30.40.30.2-0.3-0.4-0.4-0.4-0.50.5-0.10.10.00.1
Change in fecal boli incidents, locomotor task0.10.10.9-0.30.2-0.20.2-0.10.10.10.10.0-0.10.10.1-0.10.2-0.4-0.0-0.10.10.9
Time >=10cm from walls, locomotor time 10.10.10.5-0.3-0.00.00.1-0.10.10.00.00.3-0.00.00.00.10.10.3-0.4-0.7-0.60.2
Bouts of movement, locomotor time 11.41.62.21.11.2-1.2-1.5-1.31.31.31.31.2-1.3-1.5-1.5-1.3-1.41.2-1.2-0.9-1.11.0
Total resting periods, locomotor time 11.92.02.71.31.4-1.4-1.6-1.51.51.51.51.4-1.5-1.6-1.6-1.4-1.51.4-1.4-1.1-1.21.2
Rest time, locomotor task time 10.70.71.31.00.9-0.9-0.9-0.90.91.01.00.8-1.0-1.0-1.0-1.0-0.80.5-0.5-0.2-0.21.1
Distance moved, locomotor task time 10.20.20.5-0.7-0.50.50.60.4-0.4-0.5-0.5-0.20.50.60.60.60.6-0.20.0-0.5-0.3-0.3
Vertical activity count, locomotor time 10.10.10.2-0.4-0.10.10.40.2-0.2-0.3-0.2-0.10.30.50.50.30.4-0.20.0-0.4-0.10.1
Time >=10cm from walls, locomotor time 21.61.72.4-1.3-1.21.21.31.4-1.3-1.3-1.3-1.41.31.41.41.21.3-1.51.41.41.4-0.4
Bouts of movement, locomotor time 24.04.45.51.82.0-2.0-2.2-2.12.12.02.02.2-2.1-2.2-2.2-1.9-2.12.2-2.3-2.3-2.31.3
Total resting periods, locomotor time 24.24.45.22.02.1-2.1-2.3-2.22.12.12.12.2-2.1-2.3-2.3-2.1-2.22.2-2.2-2.0-2.11.2
Rest time, locomotor task time 21.31.52.31.51.3-1.3-1.3-1.31.31.41.41.0-1.4-1.5-1.5-1.5-1.40.6-0.7-0.1-0.21.5
Distance moved, locomotor task time 20.80.91.3-1.1-1.01.01.11.0-1.0-1.1-1.1-0.81.11.11.11.21.1-0.50.5-0.00.1-0.8
Vertical activity count, locomotor time 20.00.00.4-0.10.1-0.10.0-0.00.0-0.0-0.00.20.00.20.20.10.10.1-0.2-0.6-0.40.4
Light reinforcement 13.76.88.32.42.9-2.9-2.5-2.82.82.72.72.8-2.7-2.6-2.6-2.6-2.32.4-2.8-2.7-2.51.5
Light reinforcement 20.50.71.00.71.0-1.0-0.6-0.91.00.91.00.9-1.0-0.9-0.9-1.0-0.80.6-0.8-0.7-0.60.7
Bone: marrow area4.08.610.6-3.1-3.03.03.33.1-3.1-3.1-3.1-2.93.13.23.23.23.3-2.52.62.02.0-2.3
Bone: maximum diameter0.00.10.7-0.3-0.10.10.40.1-0.1-0.1-0.10.00.10.10.10.20.30.2-0.3-0.4-0.4-0.8
Bone: maximum force1.93.35.0-2.2-1.91.92.01.9-1.9-2.0-2.0-1.72.01.91.92.12.2-1.51.30.90.8-1.4
Bone: maximum moment1.22.13.3-1.8-1.51.51.61.5-1.5-1.6-1.6-1.41.61.51.51.61.8-1.31.00.70.7-1.1
Mean time between licks in bursts1.42.02.71.51.3-1.3-1.6-1.41.41.41.41.4-1.3-1.4-1.4-1.3-1.61.5-1.5-1.4-1.50.5
Mean num. licks in bursts0.10.10.70.1-0.10.10.20.2-0.2-0.2-0.2-0.20.20.40.40.2-0.0-0.00.30.00.20.8
Cd content in liver0.70.71.2-0.9-1.01.01.11.0-1.0-1.0-1.0-0.81.00.90.91.11.0-0.40.40.20.1-0.5
Co content in liver0.20.20.5-0.2-0.50.50.20.5-0.5-0.4-0.4-0.50.40.40.40.40.2-0.30.70.70.6-0.6
Cu content in liver1.41.77.0-1.0-1.61.60.81.4-1.4-1.3-1.4-1.31.31.00.91.30.6-0.71.21.30.9-2.6
Fe content in liver3.34.04.8-1.9-2.02.02.12.1-2.0-2.0-2.0-2.12.02.22.12.02.2-2.02.01.81.8-1.6
K content in liver0.80.81.71.31.1-1.1-0.9-0.91.01.01.00.8-1.0-0.9-1.0-1.1-0.90.7-0.4-0.3-0.11.1
Mg content in liver0.70.71.21.11.1-1.1-0.8-1.01.01.01.00.8-1.0-0.8-0.8-1.0-0.80.5-0.6-0.4-0.20.6
Mn content in liver0.40.41.10.90.8-0.8-0.4-0.60.70.70.70.4-0.7-0.6-0.7-0.9-0.5-0.00.10.50.61.0
Na content in liver0.20.20.50.60.4-0.4-0.6-0.40.40.50.50.3-0.5-0.7-0.7-0.6-0.50.4-0.10.30.10.6
Rb content in liver1.01.23.70.60.9-0.9-1.0-0.90.90.80.81.2-0.8-0.9-0.9-0.7-1.01.4-1.5-1.9-1.9-0.7
Se content in liver0.00.00.10.00.3-0.30.2-0.10.20.20.20.1-0.20.1-0.0-0.20.2-0.30.10.10.30.0
Sr content in liver0.30.30.60.60.4-0.4-0.5-0.50.50.50.50.5-0.5-0.6-0.6-0.5-0.60.8-0.6-0.5-0.60.1
Zn content in liver0.80.91.30.91.0-1.0-0.8-1.01.00.90.91.0-0.9-0.7-0.7-0.9-0.81.0-1.1-1.1-1.10.7
Bone: minimum diameter0.61.12.3-1.3-1.11.11.31.0-1.1-1.1-1.1-0.91.11.21.21.21.3-0.80.50.40.3-1.5
Time in familiar zone, hab. session 10.90.81.41.00.8-0.8-1.0-0.90.90.90.90.9-0.9-1.1-1.1-0.9-1.21.0-1.0-0.7-0.90.1
Time in novel zone, hab. session 14.44.35.4-2.1-2.02.02.02.1-2.1-2.0-2.0-2.22.02.12.12.02.1-2.32.22.12.1-1.4
Total zone transitions, hab. session 10.30.41.5-0.5-0.50.50.90.6-0.6-0.6-0.6-0.50.60.70.70.60.7-0.30.50.10.41.2
Total locomotion distance, hab. session 11.21.72.7-1.6-1.41.41.61.4-1.4-1.5-1.4-1.21.51.61.61.61.5-1.00.80.30.4-0.6
Locomotion velocity, hab. session 10.30.40.9-1.0-0.60.60.90.6-0.6-0.7-0.7-0.40.70.80.80.81.0-0.40.2-0.3-0.00.0
Time in familiar zone, hab. session 20.10.10.4-0.10.0-0.0-0.40.0-0.00.00.0-0.1-0.00.00.0-0.0-0.6-0.40.20.20.2-0.6
Time in novel zone, hab. session 20.00.00.3-0.00.1-0.10.3-0.00.00.00.00.0-0.1-0.0-0.0-0.00.50.0-0.0-0.00.10.2
Total zone transitions, hab. session 20.10.22.60.20.2-0.20.3-0.10.10.10.10.0-0.10.10.1-0.10.4-0.10.2-0.00.31.6
Total locomotion distance, hab. session 20.70.92.4-1.2-0.80.81.40.9-0.9-1.0-0.9-0.71.01.21.21.01.6-0.80.5-0.00.30.1
Locomotion velocity, hab. session 20.50.62.0-1.0-0.70.71.20.7-0.7-0.8-0.8-0.60.81.01.00.91.4-0.50.3-0.20.10.3
Novel to familiar place preference ratio1.81.92.3-1.3-1.31.31.31.4-1.3-1.3-1.3-1.41.31.31.31.21.5-1.51.51.51.5-1.4
Novelty place preference1.31.32.1-1.1-1.01.01.01.1-1.1-1.0-1.0-1.21.01.01.00.91.2-1.31.41.41.4-1.1
Time in novel zone, NPP test1.51.52.4-1.2-1.11.11.11.2-1.2-1.1-1.1-1.31.11.21.21.01.4-1.51.51.41.5-1.2
Total zone transitions, NPP test0.50.73.80.60.7-0.7-0.5-0.70.70.60.60.8-0.6-0.5-0.5-0.5-0.20.9-0.9-1.2-0.91.9
Total locomotion distance, NPP test0.30.41.2-0.7-0.50.50.70.6-0.6-0.6-0.6-0.50.60.70.70.61.1-0.70.60.20.50.6
Locomotion velocity, NPP test0.10.11.2-0.3-0.00.00.30.1-0.1-0.2-0.1-0.10.10.30.30.20.7-0.30.2-0.10.31.1
Intraocular pressure0.30.40.80.90.6-0.6-0.8-0.60.60.70.70.6-0.6-0.7-0.7-0.7-0.80.6-0.7-0.6-0.60.2
Delta distance traveled before/after self-admin0.80.92.00.71.0-1.0-0.9-0.90.90.80.81.0-0.8-0.8-0.8-0.7-0.81.0-1.2-1.4-1.20.5
Delta ambulatory time before/after self-admin1.11.22.50.91.2-1.2-1.0-1.11.01.01.01.2-1.0-0.9-0.9-0.9-1.01.2-1.3-1.6-1.40.6
Parametrial fat weight0.10.11.0-0.10.2-0.2-0.1-0.10.10.10.10.2-0.10.00.0-0.0-0.10.2-0.3-0.6-0.41.0
Pavlov. Cond. lever latency2.43.14.41.71.7-1.7-1.7-1.81.81.71.71.8-1.7-1.8-1.8-1.6-1.42.0-2.1-1.8-2.01.3
Pavlov. Cond. magazine entry latency2.83.64.5-2.0-1.91.92.02.0-2.0-2.0-2.0-2.02.02.12.12.01.5-2.01.91.61.6-1.1
Pavlov. Cond. change in total contacts2.02.13.0-1.6-1.41.41.71.5-1.5-1.5-1.5-1.41.51.71.71.51.4-1.51.41.01.2-0.9
Pavlov. Cond. index score2.32.94.5-1.6-1.61.61.61.7-1.7-1.7-1.6-1.81.71.81.81.61.1-2.12.01.92.0-1.4
Pavlov. Cond. latency score2.73.45.1-1.8-1.71.71.81.8-1.8-1.8-1.8-1.91.82.02.01.71.3-2.32.11.92.1-1.6
Pavlov. Cond. lever contacts1.21.43.0-1.0-0.90.91.11.1-1.0-1.0-1.0-1.21.01.11.10.90.8-1.61.61.51.7-0.9
Pavlov. Cond. magazine entry number4.45.47.02.42.3-2.3-2.3-2.42.42.42.42.4-2.4-2.6-2.6-2.4-1.92.6-2.4-2.1-2.21.6
Pavlov. Cond. intertrial magazine entries0.20.20.9-0.00.2-0.2-0.3-0.40.40.30.30.5-0.3-0.4-0.4-0.20.20.7-0.8-0.8-0.9-0.2
Pavlov. Cond. lever-magazine prob. diff.1.92.33.4-1.5-1.41.41.51.5-1.5-1.5-1.5-1.61.51.61.61.41.0-1.81.71.61.7-1.2
Pavlov. Cond. response bias1.92.43.6-1.5-1.51.51.51.5-1.5-1.5-1.5-1.61.51.61.61.41.2-1.91.81.71.8-0.7
Pavlov. Cond. lever latency0.20.30.70.20.7-0.7-0.5-0.60.60.60.60.7-0.6-0.4-0.4-0.6-0.30.3-0.7-0.8-0.6-0.2
Pavlov. Cond. magazine entry latency0.30.31.3-0.1-0.70.7-0.00.6-0.6-0.6-0.6-0.60.60.50.50.6-0.1-0.20.60.70.4-1.1
Pavlov. Cond. change in total contacts0.91.22.4-0.7-1.31.30.81.2-1.2-1.1-1.2-1.31.20.90.91.10.8-0.91.21.61.1-1.0
Pavlov. Cond. index score0.60.71.2-0.4-1.11.10.41.0-1.0-0.9-0.9-1.01.00.70.70.90.3-0.50.91.10.7-0.8
Pavlov. Cond. latency score0.60.71.1-0.5-1.01.00.51.0-1.0-0.9-1.0-1.01.00.70.70.90.4-0.50.91.00.7-0.7
Pavlov. Cond. lever contacts0.50.71.6-0.4-0.90.90.70.9-0.9-0.9-0.9-1.00.90.70.70.80.6-0.71.11.31.0-0.2
Pavlov. Cond. magazine entry number0.81.01.90.51.1-1.1-0.4-1.11.01.01.01.1-1.0-0.9-0.9-0.9-0.40.9-1.2-1.4-1.11.1
Pavlov. Cond. intertrial magazine entries0.91.21.60.71.2-1.2-0.7-1.21.21.11.11.2-1.2-1.1-1.1-1.1-0.71.0-1.3-1.3-1.10.6
Pavlov. Cond. lever-magazine prob. diff.0.30.40.7-0.1-0.80.80.10.7-0.7-0.6-0.7-0.70.70.40.40.60.1-0.20.70.90.5-0.7
Pavlov. Cond. response bias1.01.42.3-0.7-1.31.30.91.3-1.3-1.2-1.3-1.41.31.11.11.20.8-1.01.41.51.2-1.0
Time in closed arm before self-admin3.13.64.7-1.7-1.91.91.81.9-1.9-1.9-1.9-2.01.91.91.91.81.8-2.22.12.02.1-0.8
Time in closed arm after self-admin0.20.20.9-0.2-0.30.30.50.5-0.5-0.5-0.4-0.50.50.50.50.40.5-0.20.50.40.4-1.0
Time in open arm before self-admin3.94.27.51.61.8-1.8-2.0-2.02.01.91.92.2-1.9-2.1-2.1-1.7-2.12.5-2.6-2.5-2.71.1
Time in open arm after self-admin2.93.24.2-2.0-1.91.91.91.8-1.8-1.8-1.8-1.81.81.81.81.82.0-2.01.61.51.5-1.3
Bone: periosteal estimation2.24.46.5-2.4-2.22.22.42.2-2.2-2.2-2.2-2.02.22.32.32.32.6-1.71.61.21.2-2.2
Bone: periosteal perimeter1.01.62.6-1.5-1.31.31.51.2-1.3-1.3-1.3-1.11.31.31.31.41.6-0.90.80.50.5-1.6
Bone: post-yield work1.31.83.0-1.7-1.51.51.41.4-1.4-1.5-1.5-1.31.51.21.21.51.7-1.10.90.80.6-0.6
Progressive ratio test 1 active lever presses0.10.10.20.10.2-0.2-0.4-0.30.30.30.30.3-0.3-0.4-0.4-0.3-0.40.2-0.4-0.2-0.4-0.2
Progressive ratio test 1 breakpoint0.10.10.20.20.2-0.2-0.5-0.30.30.30.30.3-0.4-0.5-0.5-0.3-0.40.2-0.3-0.2-0.3-0.1
Progressive ratio test 1 inactive lever presses0.00.00.20.2-0.10.1-0.2-0.10.10.10.10.1-0.1-0.2-0.2-0.1-0.20.4-0.1-0.0-0.2-0.3
Progressive ratio test 2 active lever presses0.10.10.2-0.4-0.40.40.20.2-0.2-0.3-0.3-0.20.20.10.10.30.3-0.20.00.2-0.0-0.3
Progressive ratio test 2 breakpoint0.00.00.1-0.1-0.10.1-0.1-0.10.10.10.10.1-0.1-0.3-0.3-0.1-0.10.0-0.20.0-0.10.1
Progressive ratio test 2 inactive lever presses0.10.20.3-0.4-0.50.50.50.4-0.4-0.4-0.4-0.40.40.30.30.40.5-0.30.30.50.2-0.4
Incentive Sensitization - Responses0.30.30.8-0.9-0.70.70.70.5-0.6-0.6-0.6-0.50.60.60.60.60.7-0.60.20.20.2-0.0
Incentive Sensitization - Breakpoint0.20.20.6-0.8-0.50.50.60.4-0.4-0.5-0.5-0.40.50.40.40.50.6-0.50.10.10.10.1
Sum of active levers in priming session hrs 5-62.62.54.0-2.0-1.61.61.81.7-1.7-1.8-1.8-1.51.81.71.71.91.7-1.21.00.40.5-1.6
Progressive ratio0.40.42.10.20.3-0.3-0.4-0.30.30.20.20.6-0.2-0.2-0.2-0.0-0.51.1-1.0-1.4-1.5-0.8
Food seeking constrained by brief footshock0.10.10.9-0.50.1-0.10.10.0-0.1-0.1-0.10.20.10.10.10.30.10.2-0.5-0.9-0.80.1
Seeking ratio, punishment vs. effort0.20.20.7-0.4-0.20.20.40.3-0.3-0.3-0.3-0.40.20.30.30.20.5-0.80.50.60.70.8
Retroperitoneal fat weight0.10.51.8-0.30.4-0.4-0.4-0.40.40.30.30.7-0.3-0.4-0.4-0.1-0.20.5-1.1-1.3-1.31.2
Reaction time number correct1.42.12.51.11.5-1.5-1.6-1.51.51.51.51.6-1.5-1.5-1.5-1.4-1.51.3-1.4-1.6-1.41.0
Reaction time mean minus median3.34.35.9-2.4-2.12.12.32.1-2.1-2.1-2.1-2.22.01.91.92.02.4-2.41.92.21.9-1.4
Reaction time mean minus median AUC2.43.14.3-2.1-1.71.71.91.8-1.8-1.7-1.7-1.81.71.51.51.72.0-2.01.51.71.5-1.7
Reaction time num false alarms4.35.89.82.32.2-2.2-2.4-2.32.32.22.22.6-2.2-2.3-2.3-2.1-2.43.1-2.8-2.9-3.01.2
Reaction time num false alarms AUC4.25.99.42.42.2-2.2-2.4-2.42.32.32.32.6-2.2-2.3-2.3-2.1-2.43.1-2.7-2.8-2.91.5
Reaction time trials correct on left1.42.12.51.11.5-1.5-1.6-1.51.51.51.51.6-1.5-1.5-1.5-1.4-1.51.3-1.4-1.6-1.41.0
Reaction time trials on left1.31.92.41.01.5-1.5-1.5-1.41.41.41.41.5-1.4-1.4-1.4-1.4-1.41.2-1.4-1.5-1.31.0
Reaction time mean7.610.714.6-3.8-3.63.63.43.4-3.5-3.5-3.5-3.33.53.33.33.53.6-3.12.82.52.3-1.9
Reaction time mean AUC6.79.112.9-3.6-3.33.33.13.2-3.2-3.2-3.2-3.13.23.03.03.33.4-2.92.62.32.1-1.7
Median of all reaction times6.99.413.3-3.6-3.43.43.13.3-3.3-3.3-3.4-3.13.33.23.23.43.3-2.72.62.11.9-1.7
Reaction time omissions0.40.51.3-1.1-0.70.70.80.7-0.7-0.7-0.7-0.70.70.60.60.71.0-0.80.50.50.40.6
Reaction time false alarm rate1.72.34.61.71.3-1.3-1.5-1.41.41.41.41.6-1.3-1.4-1.4-1.3-1.52.2-1.8-1.8-2.00.9
Reaction time premature initiation rate0.00.00.1-0.00.0-0.0-0.1-0.10.10.10.10.0-0.1-0.2-0.2-0.1-0.1-0.2-0.2-0.0-0.1-0.1
Reaction time premature initiations0.40.60.90.50.8-0.8-0.8-0.80.80.80.80.8-0.8-0.9-0.9-0.8-0.80.5-0.9-0.8-0.80.5
Std. dev. reaction times7.310.212.1-3.5-3.33.33.33.3-3.3-3.3-3.3-3.43.33.13.13.33.4-3.33.13.12.8-2.1
Reaction time trials completed1.31.92.41.01.5-1.5-1.5-1.41.41.41.41.5-1.4-1.4-1.4-1.4-1.41.2-1.4-1.5-1.31.0
Reaction time trials AUC1.31.82.21.01.5-1.5-1.4-1.41.41.41.41.5-1.4-1.4-1.4-1.4-1.31.2-1.3-1.5-1.31.0
Run reversals in cocaine runway, females0.10.10.6-0.30.1-0.10.0-0.20.20.10.10.3-0.1-0.1-0.1-0.00.00.2-0.7-0.8-0.80.5
Run reversals in cocaine runway, males0.90.82.10.50.8-0.8-0.8-0.90.80.80.81.0-0.8-0.8-0.8-0.7-0.81.1-1.3-1.4-1.40.3
Latency to leave start box in cocaine runway6.46.910.23.22.8-2.8-2.8-2.72.72.72.72.7-2.7-2.7-2.7-2.7-2.92.8-2.3-2.1-2.01.7
Latency to leave start box in cocaine runway, F3.94.36.62.52.3-2.3-2.2-2.12.12.22.21.9-2.2-2.2-2.2-2.3-2.21.6-1.3-0.8-0.72.6
Latency to leave start box in cocaine runway, M2.92.87.01.71.3-1.3-1.5-1.41.41.31.31.7-1.3-1.3-1.4-1.2-1.62.7-2.0-2.3-2.4-1.3
Std. dev. time between licks in bursts6.17.38.42.72.8-2.8-2.6-2.92.92.82.92.8-2.9-2.9-2.9-2.8-2.52.6-2.8-2.4-2.41.5
Total sessions with >9 infusions0.70.81.90.60.6-0.6-0.9-0.80.80.80.81.0-0.8-0.8-0.8-0.7-0.91.1-1.2-1.3-1.4-0.3
Short access day 1 total inactive lever presses0.00.00.1-0.1-0.00.0-0.0-0.00.00.00.00.0-0.0-0.1-0.10.0-0.1-0.0-0.2-0.1-0.20.3
Short access day 10 total inactive lever presses0.70.71.1-0.8-0.90.91.00.9-0.9-0.9-0.9-0.91.00.90.91.01.0-0.60.60.50.4-1.0
Short access day 1 total infusions0.10.10.20.30.1-0.1-0.4-0.20.20.30.30.1-0.3-0.4-0.4-0.3-0.40.20.00.30.2-0.3
Short access day 10 total infusions0.10.10.30.2-0.10.1-0.6-0.30.30.30.30.2-0.3-0.5-0.5-0.3-0.50.1-0.10.40.0-0.0
Short access total infusions0.30.40.80.40.3-0.3-0.9-0.60.60.60.60.6-0.6-0.8-0.8-0.6-0.80.6-0.6-0.2-0.50.2
Short access day 1 locomotion0.10.10.40.50.1-0.1-0.5-0.30.30.30.30.3-0.3-0.4-0.4-0.3-0.50.6-0.4-0.1-0.4-0.4
Short access day 10 total locomotion0.10.10.4-0.4-0.50.50.40.4-0.4-0.4-0.4-0.30.40.30.30.50.4-0.1-0.1-0.1-0.3-0.6
Short access total locomotion0.30.31.10.30.2-0.2-0.6-0.40.40.40.40.5-0.4-0.5-0.5-0.3-0.60.8-0.9-0.7-1.1-0.3
One hour access (0.3 mA shock)0.10.10.2-0.2-0.30.30.30.3-0.3-0.3-0.3-0.30.30.30.30.30.3-0.30.40.40.4-0.4
Compulsive drug intake0.10.11.00.30.5-0.5-0.2-0.30.30.30.30.3-0.3-0.1-0.1-0.3-0.20.2-0.2-0.5-0.21.0
One hour access (shock baseline)0.20.20.7-0.5-0.60.60.30.4-0.4-0.4-0.4-0.50.40.30.30.40.3-0.50.50.70.5-0.9
Social response proportion1.31.43.1-1.6-1.11.11.41.1-1.1-1.2-1.1-1.01.11.31.31.21.8-1.10.80.50.7-1.4
Social responses0.10.10.5-0.7-0.10.10.40.1-0.1-0.1-0.10.00.10.20.20.20.7-0.1-0.3-0.4-0.3-0.6
Social time0.81.02.2-1.4-0.90.91.20.9-0.9-0.9-0.9-1.00.90.80.80.91.5-1.31.01.01.1-0.3
Soleus weight0.30.82.40.70.7-0.7-0.7-0.80.80.70.70.9-0.7-0.8-0.8-0.6-0.51.2-1.4-1.3-1.5-0.7
Bone: stiffness1.32.13.4-1.8-1.61.61.81.5-1.6-1.6-1.6-1.31.61.61.61.81.8-0.90.70.30.2-1.0
Tibialis anterior weight2.68.711.12.73.1-3.1-2.5-3.13.13.03.03.2-3.0-2.8-2.8-2.9-2.53.0-3.3-3.3-3.02.4
Time to tail flick, vehicle, before self-admin0.70.70.90.80.9-0.9-0.8-0.90.90.90.90.9-0.9-0.9-0.9-0.9-0.80.9-0.8-0.7-0.70.7
Time to tail flick, vehicle, after self-admin0.10.20.6-0.3-0.40.40.30.4-0.4-0.4-0.4-0.30.40.50.50.40.2-0.40.30.10.2-0.8
Time to tail flick, test, before self-admin1.41.33.10.81.0-1.0-1.1-1.11.01.00.91.2-1.0-1.1-1.1-0.8-1.01.4-1.5-1.7-1.70.8
Time to tail flick, test, after self-admin1.71.72.21.51.3-1.3-1.3-1.41.41.41.41.4-1.4-1.3-1.3-1.4-1.51.5-1.2-1.1-1.10.6
Delta time to tail flick, vehicle, before/after SA1.01.01.3-0.9-1.01.01.01.0-1.0-1.0-1.0-1.01.01.21.21.00.9-1.11.00.70.9-0.9
Delta time to tail flick, test, before/after SA0.20.21.40.50.3-0.3-0.1-0.20.20.30.3-0.1-0.3-0.1-0.1-0.5-0.2-0.40.71.01.20.1
Tibia length4.312.215.6-3.9-3.73.73.43.7-3.7-3.7-3.7-3.53.73.63.63.83.5-3.12.92.42.2-3.8
Ambulatory time before self-admin5.15.37.0-2.7-2.52.52.42.4-2.4-2.4-2.4-2.42.42.32.32.42.5-2.42.01.91.8-1.3
Ambulatory time after self-admin0.30.30.7-0.8-0.50.50.70.5-0.6-0.6-0.6-0.40.60.60.60.70.8-0.40.2-0.1-0.0-0.2
Bone: tissue strength0.00.00.1-0.0-0.00.0-0.2-0.00.00.10.00.0-0.0-0.1-0.1-0.0-0.3-0.1-0.20.0-0.2-0.2
Total heroin consumption0.91.11.9-0.6-0.80.81.01.0-1.0-0.9-0.9-1.10.91.01.00.81.0-1.11.41.31.4-1.3
Bone: trabecular number1.21.93.2-1.1-1.41.41.61.4-1.4-1.3-1.3-1.51.31.11.11.21.6-1.41.61.81.6-0.5
Bone: trabecular spacing0.30.32.30.20.4-0.4-0.4-0.40.30.20.30.6-0.20.20.2-0.1-0.20.6-0.9-1.5-1.2-0.4
Bone: trabecular thickness3.13.88.1-1.7-1.91.92.11.9-1.9-1.7-1.8-2.21.71.51.51.61.7-2.22.42.82.6-0.7
Bone: trabecular tissue density0.20.30.6-0.6-0.50.50.60.5-0.5-0.6-0.6-0.30.60.50.50.70.6-0.0-0.1-0.4-0.5-0.8
Water consumed over 24 hours0.50.61.10.81.0-1.0-0.9-0.90.90.90.90.8-0.9-0.7-0.7-0.9-0.70.5-0.4-0.6-0.20.7
Number of responses in last shaping day0.50.51.20.80.4-0.4-1.0-0.60.60.60.60.6-0.6-0.8-0.8-0.6-1.11.1-0.7-0.4-0.8-0.2